CINXE.COM
Role of Radiotherapy in Treating Hepatocellular Carcinoma – Cancer Science
<!DOCTYPE html> <html lang="en-US"> <head> <meta charset="UTF-8"> <title>Role of Radiotherapy in Treating Hepatocellular Carcinoma – Cancer Science</title> <meta name='robots' content='max-image-preview:large' /> <style>img:is([sizes="auto" i], [sizes^="auto," i]) { contain-intrinsic-size: 3000px 1500px }</style> <meta name="viewport" content="width=device-width, initial-scale=1"><link href='https://fonts.gstatic.com' crossorigin rel='preconnect' /> <link href='https://fonts.googleapis.com' crossorigin rel='preconnect' /> <link rel="alternate" type="application/rss+xml" title="Cancer Science » Feed" href="https://cancerscience.net/archive/feed/" /> <script> window._wpemojiSettings = {"baseUrl":"https:\/\/s.w.org\/images\/core\/emoji\/15.0.3\/72x72\/","ext":".png","svgUrl":"https:\/\/s.w.org\/images\/core\/emoji\/15.0.3\/svg\/","svgExt":".svg","source":{"concatemoji":"https:\/\/cancerscience.net\/archive\/wp-includes\/js\/wp-emoji-release.min.js?ver=6.7.1"}}; /*! This file is auto-generated */ !function(i,n){var o,s,e;function c(e){try{var t={supportTests:e,timestamp:(new Date).valueOf()};sessionStorage.setItem(o,JSON.stringify(t))}catch(e){}}function p(e,t,n){e.clearRect(0,0,e.canvas.width,e.canvas.height),e.fillText(t,0,0);var t=new Uint32Array(e.getImageData(0,0,e.canvas.width,e.canvas.height).data),r=(e.clearRect(0,0,e.canvas.width,e.canvas.height),e.fillText(n,0,0),new Uint32Array(e.getImageData(0,0,e.canvas.width,e.canvas.height).data));return t.every(function(e,t){return e===r[t]})}function u(e,t,n){switch(t){case"flag":return n(e,"\ud83c\udff3\ufe0f\u200d\u26a7\ufe0f","\ud83c\udff3\ufe0f\u200b\u26a7\ufe0f")?!1:!n(e,"\ud83c\uddfa\ud83c\uddf3","\ud83c\uddfa\u200b\ud83c\uddf3")&&!n(e,"\ud83c\udff4\udb40\udc67\udb40\udc62\udb40\udc65\udb40\udc6e\udb40\udc67\udb40\udc7f","\ud83c\udff4\u200b\udb40\udc67\u200b\udb40\udc62\u200b\udb40\udc65\u200b\udb40\udc6e\u200b\udb40\udc67\u200b\udb40\udc7f");case"emoji":return!n(e,"\ud83d\udc26\u200d\u2b1b","\ud83d\udc26\u200b\u2b1b")}return!1}function f(e,t,n){var r="undefined"!=typeof WorkerGlobalScope&&self instanceof WorkerGlobalScope?new OffscreenCanvas(300,150):i.createElement("canvas"),a=r.getContext("2d",{willReadFrequently:!0}),o=(a.textBaseline="top",a.font="600 32px Arial",{});return e.forEach(function(e){o[e]=t(a,e,n)}),o}function t(e){var t=i.createElement("script");t.src=e,t.defer=!0,i.head.appendChild(t)}"undefined"!=typeof Promise&&(o="wpEmojiSettingsSupports",s=["flag","emoji"],n.supports={everything:!0,everythingExceptFlag:!0},e=new Promise(function(e){i.addEventListener("DOMContentLoaded",e,{once:!0})}),new Promise(function(t){var n=function(){try{var e=JSON.parse(sessionStorage.getItem(o));if("object"==typeof e&&"number"==typeof e.timestamp&&(new Date).valueOf()<e.timestamp+604800&&"object"==typeof e.supportTests)return e.supportTests}catch(e){}return null}();if(!n){if("undefined"!=typeof Worker&&"undefined"!=typeof OffscreenCanvas&&"undefined"!=typeof URL&&URL.createObjectURL&&"undefined"!=typeof Blob)try{var e="postMessage("+f.toString()+"("+[JSON.stringify(s),u.toString(),p.toString()].join(",")+"));",r=new Blob([e],{type:"text/javascript"}),a=new Worker(URL.createObjectURL(r),{name:"wpTestEmojiSupports"});return void(a.onmessage=function(e){c(n=e.data),a.terminate(),t(n)})}catch(e){}c(n=f(s,u,p))}t(n)}).then(function(e){for(var t in e)n.supports[t]=e[t],n.supports.everything=n.supports.everything&&n.supports[t],"flag"!==t&&(n.supports.everythingExceptFlag=n.supports.everythingExceptFlag&&n.supports[t]);n.supports.everythingExceptFlag=n.supports.everythingExceptFlag&&!n.supports.flag,n.DOMReady=!1,n.readyCallback=function(){n.DOMReady=!0}}).then(function(){return e}).then(function(){var e;n.supports.everything||(n.readyCallback(),(e=n.source||{}).concatemoji?t(e.concatemoji):e.wpemoji&&e.twemoji&&(t(e.twemoji),t(e.wpemoji)))}))}((window,document),window._wpemojiSettings); </script> <style id='wp-emoji-styles-inline-css'> img.wp-smiley, img.emoji { display: inline !important; border: none !important; box-shadow: none !important; height: 1em !important; width: 1em !important; margin: 0 0.07em !important; vertical-align: -0.1em !important; background: none !important; padding: 0 !important; } </style> <link rel='stylesheet' id='wp-block-library-css' href='https://cancerscience.net/archive/wp-includes/css/dist/block-library/style.min.css?ver=6.7.1' media='all' /> <style id='classic-theme-styles-inline-css'> /*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} </style> <style id='global-styles-inline-css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--color--contrast: var(--contrast);--wp--preset--color--contrast-2: var(--contrast-2);--wp--preset--color--contrast-3: var(--contrast-3);--wp--preset--color--base: var(--base);--wp--preset--color--base-2: var(--base-2);--wp--preset--color--base-3: var(--base-3);--wp--preset--color--accent: var(--accent);--wp--preset--color--accent-2: var(--accent-2);--wp--preset--color--accent-hover: var(--accent-hover);--wp--preset--color--highlight: var(--highlight);--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:where(.is-layout-flex){gap: 0.5em;}:where(.is-layout-grid){gap: 0.5em;}body .is-layout-flex{display: flex;}.is-layout-flex{flex-wrap: wrap;align-items: center;}.is-layout-flex > :is(*, div){margin: 0;}body .is-layout-grid{display: grid;}.is-layout-grid > :is(*, div){margin: 0;}:where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;}:where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} :where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;} :where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;} :root :where(.wp-block-pullquote){font-size: 1.5em;line-height: 1.6;} </style> <link rel='stylesheet' id='parent-style-css' href='https://cancerscience.net/archive/wp-content/themes/generatepress/style.css?ver=6.7.1' media='all' /> <link rel='stylesheet' id='generate-widget-areas-css' href='https://cancerscience.net/archive/wp-content/themes/generatepress/assets/css/components/widget-areas.min.css?ver=3.4.0' media='all' /> <link rel='stylesheet' id='generate-style-css' href='https://cancerscience.net/archive/wp-content/themes/generatepress/assets/css/main.min.css?ver=3.4.0' media='all' /> <style id='generate-style-inline-css'> body{background-color:var(--base);color:var(--contrast);}a{color:#1b78e2;}a:hover, a:focus, a:active{color:var(--accent-hover);}.wp-block-group__inner-container{max-width:1200px;margin-left:auto;margin-right:auto;}.site-header .header-image{width:200px;}:root{--contrast:#212121;--contrast-2:#2f4468;--contrast-3:#878787;--base:#fafafa;--base-2:#f7f8f9;--base-3:#ffffff;--accent:#242226;--accent-2:#1b78e2;--accent-hover:#35343a;--highlight:#83b0de;}:root .has-contrast-color{color:var(--contrast);}:root .has-contrast-background-color{background-color:var(--contrast);}:root .has-contrast-2-color{color:var(--contrast-2);}:root .has-contrast-2-background-color{background-color:var(--contrast-2);}:root .has-contrast-3-color{color:var(--contrast-3);}:root .has-contrast-3-background-color{background-color:var(--contrast-3);}:root .has-base-color{color:var(--base);}:root .has-base-background-color{background-color:var(--base);}:root .has-base-2-color{color:var(--base-2);}:root .has-base-2-background-color{background-color:var(--base-2);}:root .has-base-3-color{color:var(--base-3);}:root .has-base-3-background-color{background-color:var(--base-3);}:root .has-accent-color{color:var(--accent);}:root .has-accent-background-color{background-color:var(--accent);}:root .has-accent-2-color{color:var(--accent-2);}:root .has-accent-2-background-color{background-color:var(--accent-2);}:root .has-accent-hover-color{color:var(--accent-hover);}:root .has-accent-hover-background-color{background-color:var(--accent-hover);}:root .has-highlight-color{color:var(--highlight);}:root .has-highlight-background-color{background-color:var(--highlight);}.gp-modal:not(.gp-modal--open):not(.gp-modal--transition){display:none;}.gp-modal--transition:not(.gp-modal--open){pointer-events:none;}.gp-modal-overlay:not(.gp-modal-overlay--open):not(.gp-modal--transition){display:none;}.gp-modal__overlay{display:none;position:fixed;top:0;left:0;right:0;bottom:0;background:rgba(0,0,0,0.2);display:flex;justify-content:center;align-items:center;z-index:10000;backdrop-filter:blur(3px);transition:opacity 500ms ease;opacity:0;}.gp-modal--open:not(.gp-modal--transition) .gp-modal__overlay{opacity:1;}.gp-modal__container{max-width:100%;max-height:100vh;transform:scale(0.9);transition:transform 500ms ease;padding:0 10px;}.gp-modal--open:not(.gp-modal--transition) .gp-modal__container{transform:scale(1);}.search-modal-fields{display:flex;}.gp-search-modal .gp-modal__overlay{align-items:flex-start;padding-top:25vh;background:var(--gp-search-modal-overlay-bg-color);}.search-modal-form{width:500px;max-width:100%;background-color:var(--gp-search-modal-bg-color);color:var(--gp-search-modal-text-color);}.search-modal-form .search-field, .search-modal-form .search-field:focus{width:100%;height:60px;background-color:transparent;border:0;appearance:none;color:currentColor;}.search-modal-fields button, .search-modal-fields button:active, .search-modal-fields button:focus, .search-modal-fields button:hover{background-color:transparent;border:0;color:currentColor;width:60px;}body, button, input, select, textarea{font-family:Open Sans, sans-serif;font-size:17px;}.main-title{font-size:25px;}.widget-title{font-weight:600;}button:not(.menu-toggle),html input[type="button"],input[type="reset"],input[type="submit"],.button,.wp-block-button .wp-block-button__link{font-size:15px;}h1{font-weight:600;font-size:40px;}h2{font-weight:600;font-size:30px;}h3{font-size:20px;}.top-bar{background-color:#636363;color:#ffffff;}.top-bar a{color:#ffffff;}.top-bar a:hover{color:#303030;}.site-header{background-color:#ffffff;color:#3a3a3a;}.site-header a{color:#3a3a3a;}.main-title a,.main-title a:hover{color:#ffffff;}.site-description{color:#757575;}.main-navigation,.main-navigation ul ul{background-color:var(--base);}.main-navigation .main-nav ul li a, .main-navigation .menu-toggle, .main-navigation .menu-bar-items{color:var(--contrast);}.main-navigation .main-nav ul li:not([class*="current-menu-"]):hover > a, .main-navigation .main-nav ul li:not([class*="current-menu-"]):focus > a, .main-navigation .main-nav ul li.sfHover:not([class*="current-menu-"]) > a, .main-navigation .menu-bar-item:hover > a, .main-navigation .menu-bar-item.sfHover > a{color:var(--base-3);background-color:var(--contrast);}button.menu-toggle:hover,button.menu-toggle:focus{color:var(--contrast);}.main-navigation .main-nav ul li[class*="current-menu-"] > a{color:var(--base-3);background-color:var(--accent-hover);}.navigation-search input[type="search"],.navigation-search input[type="search"]:active, .navigation-search input[type="search"]:focus, .main-navigation .main-nav ul li.search-item.active > a, .main-navigation .menu-bar-items .search-item.active > a{color:var(--base-3);background-color:var(--contrast);}.separate-containers .inside-article, .separate-containers .comments-area, .separate-containers .page-header, .one-container .container, .separate-containers .paging-navigation, .inside-page-header{background-color:var(--base-3);}.inside-article a,.paging-navigation a,.comments-area a,.page-header a{color:var(--accent-2);}.inside-article a:hover,.paging-navigation a:hover,.comments-area a:hover,.page-header a:hover{color:var(--accent-hover);}.entry-title a{color:var(--contrast);}.entry-title a:hover{color:var(--accent-hover);}.entry-meta{color:var(--contrast-3);}.entry-meta a{color:var(--contrast);}.entry-meta a:hover{color:var(--accent-hover);}h1{color:var(--contrast);}h2{color:var(--contrast);}h3{color:var(--contrast);}.sidebar .widget{background-color:#ffffff;}.sidebar .widget a{color:var(--contrast);padding:0px;}.sidebar .widget a:hover{color:var(--accent-hover);}.sidebar .widget .widget-title{color:#000000;}.footer-widgets{color:var(--base-3);background-color:var(--contrast-2);}.footer-widgets a{color:var(--base-3);}.footer-widgets a:hover{color:var(--base-3);}.footer-widgets .widget-title{color:var(--base-2);}.site-info{color:var(--contrast-2);}.site-info a{color:var(--contrast-2);}.site-info a:hover{color:var(--accent-hover);}.footer-bar .widget_nav_menu .current-menu-item a{color:var(--accent-hover);}input[type="text"],input[type="email"],input[type="url"],input[type="password"],input[type="search"],input[type="tel"],input[type="number"],textarea,select{color:var(--contrast);background-color:#fafafa;border-color:var(--contrast);}input[type="text"]:focus,input[type="email"]:focus,input[type="url"]:focus,input[type="password"]:focus,input[type="search"]:focus,input[type="tel"]:focus,input[type="number"]:focus,textarea:focus,select:focus{color:var(--contrast-3);background-color:#ffffff;border-color:var(--contrast-3);}button,html input[type="button"],input[type="reset"],input[type="submit"],a.button,a.wp-block-button__link:not(.has-background){color:#ffffff;background-color:var(--accent);}button:hover,html input[type="button"]:hover,input[type="reset"]:hover,input[type="submit"]:hover,a.button:hover,button:focus,html input[type="button"]:focus,input[type="reset"]:focus,input[type="submit"]:focus,a.button:focus,a.wp-block-button__link:not(.has-background):active,a.wp-block-button__link:not(.has-background):focus,a.wp-block-button__link:not(.has-background):hover{color:#ffffff;background-color:var(--accent-hover);}a.generate-back-to-top{background-color:rgba( 0,0,0,0.4 );color:#ffffff;}a.generate-back-to-top:hover,a.generate-back-to-top:focus{background-color:rgba( 0,0,0,0.6 );color:#ffffff;}:root{--gp-search-modal-bg-color:var(--base-3);--gp-search-modal-text-color:var(--contrast);--gp-search-modal-overlay-bg-color:rgba(0,0,0,0.2);}@media (max-width: 768px){.main-navigation .menu-bar-item:hover > a, .main-navigation .menu-bar-item.sfHover > a{background:none;color:var(--contrast);}}.inside-top-bar{padding:10px;}.inside-header{padding:40px;}.nav-below-header .main-navigation .inside-navigation.grid-container, .nav-above-header .main-navigation .inside-navigation.grid-container{padding:0px 20px 0px 20px;}.separate-containers .inside-article, .separate-containers .comments-area, .separate-containers .page-header, .separate-containers .paging-navigation, .one-container .site-content, .inside-page-header{padding:50px;}.site-main .wp-block-group__inner-container{padding:50px;}.separate-containers .paging-navigation{padding-top:20px;padding-bottom:20px;}.entry-content .alignwide, body:not(.no-sidebar) .entry-content .alignfull{margin-left:-50px;width:calc(100% + 100px);max-width:calc(100% + 100px);}.one-container.right-sidebar .site-main,.one-container.both-right .site-main{margin-right:50px;}.one-container.left-sidebar .site-main,.one-container.both-left .site-main{margin-left:50px;}.one-container.both-sidebars .site-main{margin:0px 50px 0px 50px;}.one-container.archive .post:not(:last-child):not(.is-loop-template-item), .one-container.blog .post:not(:last-child):not(.is-loop-template-item){padding-bottom:50px;}.main-navigation .main-nav ul li a,.menu-toggle,.main-navigation .menu-bar-item > a{line-height:51px!important;}.navigation-search input[type="search"]{height:65px;}.rtl .menu-item-has-children .dropdown-menu-toggle{padding-left:20px;}.rtl .main-navigation .main-nav ul li.menu-item-has-children > a{padding-right:20px;}.widget-area .widget{padding:50px;}.inside-site-info{padding:20px;}@media (max-width:768px){.separate-containers .inside-article, .separate-containers .comments-area, .separate-containers .page-header, .separate-containers .paging-navigation, .one-container .site-content, .inside-page-header{padding:30px;}.site-main .wp-block-group__inner-container{padding:30px;}.inside-site-info{padding-right:10px;padding-left:10px;}.entry-content .alignwide, body:not(.no-sidebar) .entry-content .alignfull{margin-left:-30px;width:calc(100% + 60px);max-width:calc(100% + 60px);}.one-container .site-main .paging-navigation{margin-bottom:20px;}.main-navigation ul ul{background-color:var(--base)!important;}.main-navigation.toggled .main-nav > ul{background-color:var(--base)!important;}}/* End cached CSS */.is-right-sidebar{width:30%;}.is-left-sidebar{width:25%;}.site-content .content-area{width:70%;}@media (max-width: 768px){.main-navigation .menu-toggle,.sidebar-nav-mobile:not(#sticky-placeholder){display:block;}.main-navigation ul,.gen-sidebar-nav,.main-navigation:not(.slideout-navigation):not(.toggled) .main-nav > ul,.has-inline-mobile-toggle #site-navigation .inside-navigation > *:not(.navigation-search):not(.main-nav){display:none;}.nav-align-right .inside-navigation,.nav-align-center .inside-navigation{justify-content:space-between;}} .dynamic-author-image-rounded{border-radius:100%;}.dynamic-featured-image, .dynamic-author-image{vertical-align:middle;}.one-container.blog .dynamic-content-template:not(:last-child), .one-container.archive .dynamic-content-template:not(:last-child){padding-bottom:0px;}.dynamic-entry-excerpt > p:last-child{margin-bottom:0px;} .main-navigation .main-nav ul li a,.menu-toggle,.main-navigation .menu-bar-item > a{transition: line-height 300ms ease}.main-navigation.toggled .main-nav > ul{background-color: var(--accent)}.sticky-enabled .gen-sidebar-nav.is_stuck .main-navigation {margin-bottom: 0px;}.sticky-enabled .gen-sidebar-nav.is_stuck {z-index: 500;}.sticky-enabled .main-navigation.is_stuck {box-shadow: 0 2px 2px -2px rgba(0, 0, 0, .2);}.navigation-stick:not(.gen-sidebar-nav) {left: 0;right: 0;width: 100% !important;}.nav-float-right .navigation-stick {width: 100% !important;left: 0;}.nav-float-right .navigation-stick .navigation-branding {margin-right: auto;}.main-navigation.has-sticky-branding:not(.grid-container) .inside-navigation:not(.grid-container) .navigation-branding{margin-left: 10px;} </style> <link rel='stylesheet' id='generate-child-css' href='https://cancerscience.net/archive/wp-content/themes/generatepress-child/style.css?ver=1725343721' media='all' /> <link rel='stylesheet' id='generate-google-fonts-css' href='https://fonts.googleapis.com/css?family=Open+Sans%3A300%2Cregular%2Citalic%2C600%2C700&display=auto&ver=3.4.0' media='all' /> <link rel='stylesheet' id='generate-blog-images-css' href='https://cancerscience.net/archive/wp-content/plugins/gp-premium/blog/functions/css/featured-images.min.css?ver=2.4.1' media='all' /> <link rel='stylesheet' id='generate-navigation-branding-css' href='https://cancerscience.net/archive/wp-content/plugins/gp-premium/menu-plus/functions/css/navigation-branding-flex.min.css?ver=2.4.1' media='all' /> <style id='generate-navigation-branding-inline-css'> .main-navigation.has-branding .inside-navigation.grid-container, .main-navigation.has-branding.grid-container .inside-navigation:not(.grid-container){padding:0px 50px 0px 50px;}.main-navigation.has-branding:not(.grid-container) .inside-navigation:not(.grid-container) .navigation-branding{margin-left:10px;}.navigation-branding img, .site-logo.mobile-header-logo img{height:65px;width:auto;}.navigation-branding .main-title{line-height:65px;}@media (max-width: 768px){.main-navigation.has-branding.nav-align-center .menu-bar-items, .main-navigation.has-sticky-branding.navigation-stick.nav-align-center .menu-bar-items{margin-left:auto;}.navigation-branding{margin-right:auto;margin-left:10px;}.navigation-branding .main-title, .mobile-header-navigation .site-logo{margin-left:10px;}.main-navigation.has-branding .inside-navigation.grid-container{padding:0px;}} </style> <script src="https://cancerscience.net/archive/wp-includes/js/jquery/jquery.min.js?ver=3.7.1" id="jquery-core-js"></script> <link rel="https://api.w.org/" href="https://cancerscience.net/archive/wp-json/" /><link rel="alternate" title="JSON" type="application/json" href="https://cancerscience.net/archive/wp-json/wp/v2/posts/232" /><link rel="EditURI" type="application/rsd+xml" title="RSD" href="https://cancerscience.net/archive/xmlrpc.php?rsd" /> <meta name="generator" content="WordPress 6.7.1" /> <link rel="canonical" href="https://cancerscience.net/archive/hepatocellular-carcinoma/role-of-radiotherapy-in-treating-hepatocellular-carcinoma/" /> <link rel='shortlink' href='https://cancerscience.net/archive/?p=232' /> <link rel="alternate" title="oEmbed (JSON)" type="application/json+oembed" href="https://cancerscience.net/archive/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fcancerscience.net%2Farchive%2Fhepatocellular-carcinoma%2Frole-of-radiotherapy-in-treating-hepatocellular-carcinoma%2F" /> <link rel="alternate" title="oEmbed (XML)" type="text/xml+oembed" href="https://cancerscience.net/archive/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fcancerscience.net%2Farchive%2Fhepatocellular-carcinoma%2Frole-of-radiotherapy-in-treating-hepatocellular-carcinoma%2F&format=xml" /> <link rel="icon" href="https://cancerscience.net/archive/wp-content/uploads/2024/08/cropped-Favi-icon-32x32.png" sizes="32x32" /> <link rel="icon" href="https://cancerscience.net/archive/wp-content/uploads/2024/08/cropped-Favi-icon-192x192.png" sizes="192x192" /> <link rel="apple-touch-icon" href="https://cancerscience.net/archive/wp-content/uploads/2024/08/cropped-Favi-icon-180x180.png" /> <meta name="msapplication-TileImage" content="https://cancerscience.net/archive/wp-content/uploads/2024/08/cropped-Favi-icon-270x270.png" /> </head> <body class="post-template-default single single-post postid-232 single-format-standard wp-custom-logo wp-embed-responsive post-image-above-header post-image-aligned-center sticky-menu-no-transition sticky-enabled both-sticky-menu right-sidebar nav-below-header separate-containers header-aligned-left dropdown-hover featured-image-active" itemtype="https://schema.org/Blog" itemscope> <a class="screen-reader-text skip-link" href="#content" title="Skip to content">Skip to content</a> <nav class="auto-hide-sticky has-branding main-navigation nav-align-right has-menu-bar-items sub-menu-right" id="site-navigation" aria-label="Primary" itemtype="https://schema.org/SiteNavigationElement" itemscope> <div class="inside-navigation grid-container"> <div class="navigation-branding"><div class="site-logo"> <a href="https://cancerscience.net/archive/" title="Cancer Science" rel="home"> <img class="header-image is-logo-image" alt="Cancer Science" src="https://cancerscience.net/archive/wp-content/uploads/2024/08/cropped-logo.png" title="Cancer Science" width="720" height="443" /> </a> </div></div> <button class="menu-toggle" aria-controls="primary-menu" aria-expanded="false"> <span class="gp-icon icon-menu-bars"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M0 96c0-13.255 10.745-24 24-24h464c13.255 0 24 10.745 24 24s-10.745 24-24 24H24c-13.255 0-24-10.745-24-24zm0 160c0-13.255 10.745-24 24-24h464c13.255 0 24 10.745 24 24s-10.745 24-24 24H24c-13.255 0-24-10.745-24-24zm0 160c0-13.255 10.745-24 24-24h464c13.255 0 24 10.745 24 24s-10.745 24-24 24H24c-13.255 0-24-10.745-24-24z" /></svg><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M71.029 71.029c9.373-9.372 24.569-9.372 33.942 0L256 222.059l151.029-151.03c9.373-9.372 24.569-9.372 33.942 0 9.372 9.373 9.372 24.569 0 33.942L289.941 256l151.03 151.029c9.372 9.373 9.372 24.569 0 33.942-9.373 9.372-24.569 9.372-33.942 0L256 289.941l-151.029 151.03c-9.373 9.372-24.569 9.372-33.942 0-9.372-9.373-9.372-24.569 0-33.942L222.059 256 71.029 104.971c-9.372-9.373-9.372-24.569 0-33.942z" /></svg></span><span class="mobile-menu">Menu</span> </button> <div id="primary-menu" class="main-nav"><ul id="menu-primary-menu" class=" menu sf-menu"><li id="menu-item-164" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-164"><a href="https://cancerscience.net/">Home</a></li> <li id="menu-item-175" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-175"><a href="https://cancerscience.net/about/">About</a></li> <li id="menu-item-165" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-165"><a href="https://cancerscience.net/publication-trends/">Publication Trends</a></li> <li id="menu-item-166" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-166"><a href="https://cancerscience.net/recent-publications/">Recent Publications</a></li> <li id="menu-item-167" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-167"><a href="https://cancerscience.net/expert-search/">Expert Search</a></li> </ul></div><div class="menu-bar-items"> <span class="menu-bar-item"> <a href="#" role="button" aria-label="Open search" data-gpmodal-trigger="gp-search"><span class="gp-icon icon-search"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path fill-rule="evenodd" clip-rule="evenodd" d="M208 48c-88.366 0-160 71.634-160 160s71.634 160 160 160 160-71.634 160-160S296.366 48 208 48zM0 208C0 93.125 93.125 0 208 0s208 93.125 208 208c0 48.741-16.765 93.566-44.843 129.024l133.826 134.018c9.366 9.379 9.355 24.575-.025 33.941-9.379 9.366-24.575 9.355-33.941-.025L337.238 370.987C301.747 399.167 256.839 416 208 416 93.125 416 0 322.875 0 208z" /></svg><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M71.029 71.029c9.373-9.372 24.569-9.372 33.942 0L256 222.059l151.029-151.03c9.373-9.372 24.569-9.372 33.942 0 9.372 9.373 9.372 24.569 0 33.942L289.941 256l151.03 151.029c9.372 9.373 9.372 24.569 0 33.942-9.373 9.372-24.569 9.372-33.942 0L256 289.941l-151.029 151.03c-9.373 9.372-24.569 9.372-33.942 0-9.372-9.373-9.372-24.569 0-33.942L222.059 256 71.029 104.971c-9.372-9.373-9.372-24.569 0-33.942z" /></svg></span></a> </span> </div> </div> </nav> <div class="site grid-container container hfeed" id="page"> <div class="site-content" id="content"> <div class="content-area" id="primary"> <main class="site-main" id="main"> <article id="post-232" class="post-232 post type-post status-publish format-standard has-post-thumbnail hentry category-hepatocellular-carcinoma tag-hepatocellular-carcinoma tag-image-guided-radiotherapy tag-liver-cancer tag-neoadjuvant-radiotherapy tag-portal-vein-tumor-thrombus tag-radiotherapy tag-stereotactic-body-radiation-therapy tag-transarterial-chemoembolization" itemtype="https://schema.org/CreativeWork" itemscope> <div class="inside-article"> <div class="featured-image page-header-image-single "> <img width="800" height="419" src="https://cancerscience.net/archive/wp-content/uploads/2024/10/banner-01.jpg" class="attachment-full size-full" alt="" itemprop="image" decoding="async" fetchpriority="high" srcset="https://cancerscience.net/archive/wp-content/uploads/2024/10/banner-01.jpg 800w, https://cancerscience.net/archive/wp-content/uploads/2024/10/banner-01-300x157.jpg 300w, https://cancerscience.net/archive/wp-content/uploads/2024/10/banner-01-768x402.jpg 768w" sizes="(max-width: 800px) 100vw, 800px" /> </div> <header class="entry-header"> <h1 class="entry-title" itemprop="headline">Role of Radiotherapy in Treating Hepatocellular Carcinoma</h1> <div class="entry-meta"> <span class="posted-on"><time class="entry-date published" datetime="2024-10-08T16:50:31+05:30" itemprop="datePublished">October 8, 2024</time></span> <span class="byline">by <span class="author vcard" itemprop="author" itemtype="https://schema.org/Person" itemscope><a class="url fn n" href="https://cancerscience.net/archive/author/cancerscience/" title="View all posts by cancerscience" rel="author" itemprop="url"><span class="author-name" itemprop="name">cancerscience</span></a></span></span> </div> </header> <div class="entry-content" itemprop="text"> <p><span style="font-weight: 400;">Hepatocellular carcinoma, also HCC, represents the most frequent primary liver cancer and is often associated with a poor prognosis and few therapy options, especially in the late stages. HCC is a growing global health problem largely due to chronic hepatitis infections and other liver diseases, and therefore the need for appropriate treatment methods cannot be overemphasized. In all the treatment approaches, radiotherapy has come through as a powerful modality in the treatment of patients with HCC, especially those who cannot undergo surgical or other localized therapies. This article explores the role of radiotherapy in managing HCC, its advantages and shortcomings, and perspectives on its development.</span></p> <h3><b>Understanding Radiotherapy in HCC Treatment</b></h3> <p><span style="font-weight: 400;">Radiation therapy, formerly employed in some cancers such as those of the breast, lung, and prostate, has been increasingly used in liver cancers, inclusive of HCC. The liver is known though to have a low tolerance to radiation, and therefore the use of radiotherapy has in the past been restricted, but with recent developments in both technology and techniques, the role of radiotherapy has begun to increase. </span><span style="font-weight: 400;">Over the past few years, new approaches to radiotherapy have emerged in the form of stereotactic body radiation therapy (SBRT), intensity-modulated radiation therapy (IMRT), and other precision-based techniques of hepatic irradiation in an attempt to give high doses to tumors while sparing much of the normal surrounding liver tissue.</span></p> <h3><b>Stereotactic Body Radiation Therapy (SBRT)</b></h3> <p><span style="font-weight: 400;">SBRT is a very conformal radiotherapy technique where a high dose of radiation is given to the tumor in a small number of fractions. It is most helpful for small-sized HCC patients who will not benefit from surgery or other localized therapies. A total of 101 patients with small-sized HCC followed up after SBRT using an abdominal compression technique had a better prognosis with a median follow-up of more than 23 months. The 1-year, 3-year, and 5-year local control rates were high and proved that SBRT could control the tumor with a reasonable profile of complications. In particular, this paper found that the modified fractionation regimen with a total dose of 6-10 fractions was sufficient to achieve quite favorable results in terms of the control of the disease with relatively few side effects.</span></p> <p><span style="font-weight: 400;">These are helical intensity-modulated radiation therapy and image-guided radiation therapy, which boost the efficiency of SBRT. These technologies help minimize the radiation delivered to the surrounding area, thus minimizing damage to the liver and other close structures. They also require that much precision in the case of liver cancers, especially because preserving liver function is of importance to the wellbeing of the patient and his tolerance to the treatments.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Yearwise Publication Trend on <b>“<a href="https://cancerscience.net/publication-trends/index/hepatocellular carcinoma" target="_blank" title="hepatocellular carcinoma - yearwise publication trends">hepatocellular carcinoma</a>”</b></h2> </div> </div><div class="results-container"><div class="chart-block" style="padding:15px;"> <div class="left"> <div id="results" class="results"></div> </div> <div class="right"> <div class="chart-container"><canvas id="publicationChart"></canvas></div> </div> <div class="keywordsdiv"> <div style="text-align:center;"><b>Find publication trends on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-stats"></span> </div> </div></div></div><div class="inside-article"><style> table { margin: 0 0 1.5em; width: max-content; text-align: center; } @media only screen and (max-width: 993px) { .Adblock-main { width: 100% !important; margin:auto } } .Adblock-main { width: 100%; margin:auto; background-color:#fff; } .Adblock-head { background: #42c251; padding: 12px 10px; } .Adblock-head h1, .Adblock-head h2 { color: #fff; font-size: 20px; text-align: center; font-weight: 500; margin-bottom: 10px; margin-top: 8px; } .Adblock-head h1 a{ color: #000; text-decoration: none; font-size:22px; padding:0px; } .Adblock-head h1 a:hover{ color: #000; text-decoration: underline; } .Ad-title{ margin-bottom: 1px; margin-top: 5px; text-align: center; font-size: 15px; color: #000; } .Ad-title a { color: #000; text-decoration: underline; } .Ad-title a:hover{ color: #000; text-decoration: underline; } .Ad-title1 { margin-bottom: 0px; margin-top: 15px; text-align: center; font-size: 18px; color: #000; } .Ad-title1 a { color: #000; text-decoration: underline; } .Ad-title1 a:hover{ color: #000; text-decoration: underline; } .Ad-subtitle { margin-bottom: 8px; margin-top: 15px; text-align: center; } .Ad-subtitle1 { margin-bottom: 0px; margin-top: 10px; text-align: center; font-size: 16px; } .Ad-middle { border: solid 1px #ccc; padding-bottom: 20px; border-bottom: none; } .register-button { background-color: #283b39; color: #ffffff !important; padding: 10px 14px; border: none; border-radius: 5px; font-size: 14px; cursor: pointer; text-decoration: none; display: inline-block; margin-top: 15px; } .register-button span { color:#6dfe7e; } .register-button:hover { background-color: #161515; color:#fff; } .tablediv { width:100%; border: solid 1px #ccc; background:#fff; margin-bottom: 0px !important; } .tablediv th,.tablediv td{ font-size:13px!important; } .keywordsdiv { font-size: 14px; margin-bottom: 0px; background: #f1f1f1; padding: 10px 15px; margin-top: 15px; border-radius: 5px; } .keywordsdiv a{ color: #276cb5; padding: 0; } .keywordsdiv a:hover{ color:#000; text-decoration:underline; } .pub-scroll{ max-height: 260px; overflow-y: auto; overflow-x: hidden; } .chart-block { display: flex; flex-wrap: wrap; justify-content: space-between; background:#fff; border:1px solid #ccc; } .chart-block .left, .chart-block .right { background-color: #fff; padding: 20px; box-sizing: border-box; } .chart-block .left { flex: 1 1 5%; /* Takes up 45% of the width, flexible */ padding-right:0px !important } .chart-block .right { flex: 1 1 45%; /* Takes up 45% of the width, flexible */ } /* Responsive adjustments */ @media (max-width: 768px) { .chart-block .left, .chart-block .right { flex: 1 1 100%; /* Stack vertically on smaller screens */ margin: 0 0 10px 0; padding-right:20px !important } .chart-block .right{ width:50% !important; border:solid 1px #ccc; } .pub-scroll{ max-height:100% !important; overflow-y: inherit; overflow-x: hidden; } } </style> <script src='https://cdn.jsdelivr.net/npm/chart.js'></script> <script> var chart = null; function displayResults(statistics) { var resultsContainer = document.getElementById('results'); if (!statistics || Object.keys(statistics).length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var tableHTML = `<div class='pub-scroll'> <table class='tablediv' border='1' cellspacing='0' cellpadding='0'> <tr> <th>Year</th> <th>Publication Count</th> </tr>`; Object.entries(statistics).sort(([yearA], [yearB]) => yearB - yearA).forEach(([year, count]) => { const displayCount = count === 0 ? 'NA' : count; tableHTML += ` <tr> <td>${year}</td> <td>${displayCount}</td> </tr> `; }); tableHTML += '</table></div>'; resultsContainer.innerHTML = tableHTML; } function displayLineChart(statistics) { var years = Object.keys(statistics); var counts = Object.values(statistics); var ctx = document.getElementById('publicationChart').getContext('2d'); // Destroy existing chart instance if it exists if (chart !== null) { chart.destroy(); } // Create a new chart instance chart = new Chart(ctx, { type: 'line', data: { labels: years, datasets: [{ label: 'Publication Counts', data: counts, fill: false, borderColor: 'rgba(75, 192, 192, 1)', tension: 0.1 }] }, options: { scales: { y: { beginAtZero: true } }, plugins: { legend: { display: true, position: 'top' } } } }); } function displayKeywordStats(keywords) { var resultsContainer = document.getElementById('keyword-stats'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach((key, index) => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://cancerscience.net/publication-trends/index/${key_replace}" target="_blank" title="${key} - yearwise publication trends">${key}</a>`; if (index < keywords.length - 1) { keywordHTML += ', '; } }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var statistics = { "2014": 2588, "2015": 2596, "2016": 3158, "2017": 3309, "2018": 3246, "2019": 4226, "2020": 5503, "2021": 6684, "2022": 7716, "2023": 12388, "2024": 5412 }; var keywordsArray = ["Hepatocellular carcinoma","radiotherapy","stereotactic body radiation therapy","image-guided radiotherapy","neoadjuvant radiotherapy","liver cancer","portal vein tumor thrombus","transarterial chemoembolization"]; displayResults(statistics); displayLineChart(statistics); displayKeywordStats(keywordsArray); </script></p> <h3><b>Image-Guided Intensity-Modulated Radiotherapy (IG-IMRT)</b></h3> <p><span style="font-weight: 400;">IG-IMRT is yet again another addition to the list of improvements within the realm of radiotherapy for HCC. This technique entails the employment of innovative imaging equipment to direct the delivery of radiation and hence more accurately target tumors that are otherwise hard to address. In a phase 3 comparative analysis of IG-IMRT with non-IG-IMRT in HCC patients with lymph node metastasis, the evaluation of IG-IMRT exhibited better short-term survival and local tumor control. In turn, the mean biological effective dose achieved through IG-IMRT was significantly higher than in non-IG-IMRT, which promoted consequently improved rates of overall survival and the rate of one-year survival. Also, IG-IMRT resulted in less severe late hepatotoxic effects, which underscores the idea of the benefits of this method for patients with advanced disease.</span></p> <h3><b>Neoadjuvant Radiotherapy and Hepatectomy</b></h3> <p><span style="font-weight: 400;">In patients with resectable HCC combined with PVTT, external beam radiation therapy before the hepatectomy has been reported to improve the survival rate. A multicenter controlled trial has examined the results of neoadjuvant three-dimensional conformal RT followed by surgery with surgery only. The present work proved that neoadjuvant RT significantly decreased the probability of HCC-related mortality and failure regarding survival rates increasing due to the operation only.</span></p> <p><span style="font-weight: 400;">The use of neoadjuvant RT as part of the approach has certain benefits: Since neoadjuvant RT makes the tumor smaller and helps prevent the spreading of the cancer before surgery, it contributes to successful resection and lowers the chances of recurrence. Interleukin-6 (IL-6) was also identified as a biomarker that could be used to predict the response to RT according to the results of the study. The patients who completed the therapy and had low IL-6 levels got better results; thus, it can be stated that the individualization of the RT using biomarker evaluation could improve the outcomes.</span></p> <h3><b>Combination Therapies with Radiotherapy</b></h3> <p><span style="font-weight: 400;">It has therefore become common to use radiotherapy in combination with other forms of treatment, including TACE and immunotherapy. There is one more localized treatment of HCC called thermal ablation, and its effectiveness is lower if the tumor is bigger than 3 cm in size. Nevertheless, one can state that the use of ablation in conjunction with transarterial embolic therapy is more effective. This combination takes advantage of the fact that radiotherapy assists ablation therapy in the effective management of large cancers.</span></p> <p><span style="font-weight: 400;">Furthermore, approaches combining radiation with immunotherapy, especially immune checkpoint inhibitors such as patients with PD-1/PD-L1 blockade, are being investigated. This combination is planned to mobilize the body’s immune system to improve outcomes of radiotherapy in terms of its antitumor activity. Although this is one of the relatively young fields, some of the preliminary outcomes indicate that this cooperation could provide synergistic effects, especially in the treatment of advanced or inoperable HCC.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Recent Publications on <b>“<a href="https://cancerscience.net/recent-publications/index/hepatocellular carcinoma" target="_blank" rel="noopener" title="hepatocellular carcinoma - yearwise publication list">hepatocellular carcinoma</a>”</b></h2> </div> </div> <div class="pb-main"><div class="article-scroll"><div id="results_recent" class="results"></div></div><div class="keywordsdiv" style="margin: 0px 15px;margin-top:20px;"> <div style="text-align:center;"><b>Find publications on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-papers"></span> </div></div></div><div class="inside-article"> <style> .pb-main{ border: solid 1px #ccc; border-top: none; margin-bottom: 20px; padding-bottom: 25px; background:#fff; } .author-main { border: solid 1px #ccc; border-top: none; margin-bottom: 20px; padding-bottom: 25px; background:#fff; } .publication-block { padding: 10px; margin-bottom: 10px; background-color: #f9f9f9; text-align: left; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .publication-block h3 { margin: 0 0 10px; color: #000!important; } .publication-block a { font-size: 16px !important; line-height: 1em; font-weight: 600; text-transform: none; color: #000; padding: 0px; } .publication-block a:hover{ color: #227cdc; text-decoration:underline; } .article-scroll { max-height: 445px; overflow-y: auto; overflow-x: hidden; } ::-webkit-scrollbar-track { -webkit-box-shadow: inset 0 0 6px rgba(0,0,0,0.3); background-color: #efefef; border-radius:30px; } ::-webkit-scrollbar { width: 6px; background-color: #efefef; border-radius:30px; } ::-webkit-scrollbar-thumb { background-color: #ababab; border-radius:30px; } .publication-block p { margin-bottom: .5em; font-size: 15px; color: #000; } h3 { font-size: 18px !important; margin-bottom: 20px; line-height: 1.2em; font-weight: 600; text-transform: none; } a { padding: 5px; color: #a71c49; } #keyword-papers{ margin-top: 20px; text-align: center; } </style> <script> function displayResults_recent(papers) { var resultsContainer = document.getElementById('results_recent'); if (!papers || papers.length === 0) { resultsContainer.innerHTML = '<p>No recent publications found.</p>'; return; } papers.forEach(paper => { var publicationBlock = document.createElement('div'); publicationBlock.className = 'publication-block'; var publicationHTML = ` <div style="margin-bottom: 10px;line-height: 24px;"><a href="${paper.url}" target="_blank" title="${paper.title}">${paper.title}</a></div> <p><strong>Issue Release:</strong> ${paper.publishedDate}</p> `; publicationBlock.innerHTML = publicationHTML; resultsContainer.appendChild(publicationBlock); }); } function displayKeywordPapers(keywords) { var resultsContainer = document.getElementById('keyword-papers'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach((key, index) => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://cancerscience.net/recent-publications/index/${key_replace}" target="_blank" title="${key} - publication list">${key}</a>`; if (index < keywords.length - 1) { keywordHTML += ', '; } }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var recent_papers = [ { "title": "Improving hepatocellular carcinoma surveillance in the United\u00a0Kingdom: challenges and solutions.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946891", "publishedDate": "2024" }, { "title": "ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38944913", "publishedDate": "2024" }, { "title": "Frequency of and reasons behind non-listing in adult patients referred for liver transplantation: Results from a retrospective study.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947971", "publishedDate": "2024" }, { "title": "Perspective of the risk and molecular mechanisms of hepatocellular carcinoma after HCV eradication in the post-DAA era.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946463", "publishedDate": "2024" }, { "title": "LTR Retrotransposon-Derived LncRNA LINC01446 Promotes Hepatocellular Carcinoma Progression and Angiogenesis by Regulating the SRPK2\/SRSF1\/VEGF Axis.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38945203", "publishedDate": "2024" }, { "title": "Comparison of Clinical Manifestations and Related Factors of Hepatocellular Carcinoma with Chronic Hepatitis B.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947567", "publishedDate": "2024" }, { "title": "The significance of lipid metabolism reprogramming of tumor-associated macrophages in hepatocellular carcinoma.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38954021", "publishedDate": "2024" }, { "title": "Functional hydrogels for hepatocellular carcinoma: therapy, imaging, and in vitro model.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38951911", "publishedDate": "2024" }, { "title": "Cytokine release syndrome following durvalumab and tremelimumab in advanced hepatocellular carcinoma: A case report with cytokine and damage-associated molecular pattern analysis.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38943555", "publishedDate": "2024" }, { "title": "Expanding the liver donor pool worldwide with hepatitis C infected livers, is it the time?", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38947961", "publishedDate": "2024" }, { "title": "Ramucirumab for advanced hepatocellular carcinoma in the current real world: a Japanese single-arm study post-REACH-2 (The R-evolution study).", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38842657", "publishedDate": "2024" }, { "title": "EASL position paper on clinical follow-up after HCV cure.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38845253", "publishedDate": "2024" }, { "title": "Multi-omics analysis reveals mechanism of Schisandra chinensis lignans and acteoside on EMT in hepatoma cells via ERK1\/2 pathway.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38849609", "publishedDate": "2024" }, { "title": "CD151-enriched migrasomes mediate hepatocellular carcinoma invasion by conditioning cancer cells and promoting angiogenesis.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38840183", "publishedDate": "2024" }, { "title": "Radiomics model based on contrast-enhanced computed tomography imaging for early recurrence monitoring after radical resection of AFP-negative hepatocellular carcinoma.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38849749", "publishedDate": "2024" }, { "title": "The role and mechanism of SUMO modification in liver disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38878635", "publishedDate": "2024" }, { "title": "Characterizations of multi-kingdom gut microbiota in immune checkpoint inhibitor-treated hepatocellular carcinoma.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38844407", "publishedDate": "2024" }, { "title": "Immunotherapy for hepatocellular carcinoma: the next evolution in expanding access to liver transplantation.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38848767", "publishedDate": "2024" }, { "title": "Far-infrared irradiation increases the uptake of LDL cholesterol by downregulating PCSK9 through the activation of TRPV4 calcium channels in HepG2 cells.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38850809", "publishedDate": "2024" }, { "title": "Review of current and new drugs for the treatment of metabolic-associated fatty liver disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38850496", "publishedDate": "2024" } ]; var keywordsArray = ["Hepatocellular carcinoma","radiotherapy","stereotactic body radiation therapy","image-guided radiotherapy","neoadjuvant radiotherapy","liver cancer","portal vein tumor thrombus","transarterial chemoembolization"]; displayResults_recent(recent_papers); displayKeywordPapers(keywordsArray); </script></p> <h3><b>Challenges and Considerations</b></h3> <p><span style="font-weight: 400;">However, the radiation-induced plication of radiotherapy in the treatment of HCC has its shortcomings. Nevertheless. Hepatic radiation tolerance is still a critical issue, especially for patients with other liver pathologies or poor liver reserve. There is always the possibility of developing Radiation-Induced Liver Disease, or RILD, that requires strict planning and accurate dosing to avoid much damage. Besides, HCC treatment is challenging because of the tumor heterogeneity, where the patients may develop multiple tumor nodules, and the degree of liver involvement may differ.</span></p> <p><span style="font-weight: 400;">I was able to identify that another problem is related to the application of radiotherapy to previously established regimens. In patients with HCC, curative-intent treatments involve surgery, systemic therapy, and locoregional therapy. There is still much debate about when radiotherapy should commence and what other therapies it should be combined with, all of which is a difficult decision to make and involves the integration of multidisciplinary teams including oncologists, radiologists, and surgeons.</span></p> <h3><b>Future Directions in Radiotherapy for HCC</b></h3> <p><span style="font-weight: 400;">The need for technology enhancement and the application of individualized approaches are all that could define the further therapy of HCC by radiotherapy. A broad discussion of the main ideas of radiomics and its application in imaging analysis and facilitation of the development of artificial intelligence in the identification of patterns that inform treatment outcomes. Some of them might point to biomarkers that correlate with a better response to radiotherapy, allowing personalized treatment plans that would combine the best of this therapy with minimal side effects.</span></p> <p><span style="font-weight: 400;">Furthermore, the discovery of new technologies in radiotherapy, for instance, proton beam therapy (PTB) and carbon ion therapy (CIT), will provide better precision and outcome in comparison to conventional treatments. These therapies give radiation in a manner that affects healthy tissues still more gently than current modalities and hence are well suited to tackle HCC patients with tough or bulky tumors.</span></p> <p><span style="font-weight: 400;">It is also necessary to carry on further studies of combined therapy. A combination of radiotherapy with other new stellar therapies, like, for example, targeted therapy and novel immunotherapies may open up new therapeutic possibilities for HCC patients. Only clinical trials aiming at investigating the safety, efficacy, and way of using these above-mentioned combinations will prove it.</span></p> <h3><b>Conclusion</b></h3> <p><span style="font-weight: 400;">Radiotherapy has undoubtedly been proven to be an essential instrument for the treatment of HCC. The development of technology in radiation oncology allows the use of radiotherapy as a feasible and reasonable treatment strategy for HCC, irrespective of the stage of the disease in the patient. Of course, there are obstacles in the management of HCC, but if radiotherapy works to increase survival rates and make the quality of these patients’ lives significantly better, it would be a great thing. As researchers continue to drive the limits of the modality, radiotherapy is expected to occupy a more pivotal position in the comprehensive management of hepatocellular carcinoma.</span></p> <p></p> <h3><b>References</b></h3> <ol> <li>Chen, Y.X., Zhuang, Y., Yang, P., Fan, J., Zhou, J., Hu, Y., Zhu, W.C., Sun, J. and Zeng, Z.C., 2020. <a href="https://journals.sagepub.com/doi/full/10.1177/1533033820937002">Helical IMRT-based stereotactic body radiation therapy using an abdominal compression technique and modified fractionation regimen for small hepatocellular carcinoma.</a> <i>Technology in Cancer Research & Treatment</i>, <i>19</i>, p.1533033820937002.</li> <li>Jang, W.I., Bae, S.H., Kim, M.S., Han, C.J., Park, S.C., Kim, S.B., Cho, E.H., Choi, C.W., Kim, K.S., Hwang, S. and Kim, J.H., 2020. <a href="https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.32502">A phase 2 multicenter study of stereotactic body radiotherapy for hepatocellular carcinoma: Safety and efficacy.</a> <i>Cancer</i>, <i>126</i>(2), pp.363-372.</li> <li>Zhang, H., Chen, Y., Hu, Y., Yang, P., Wang, B., Zhang, J., Sun, J. and Zeng, Z., 2019. <a href="https://apm.amegroups.org/article/view/32182">Image-guided intensity-modulated radiotherapy improves short-term survival for abdominal lymph node metastases from hepatocellular carcinoma.</a> <i>Annals of Palliative Medicine</i>, <i>8</i>(5), pp.71727-71727.</li> <li>Wei, X., Jiang, Y., Zhang, X., Feng, S., Zhou, B., Ye, X., Xing, H., Xu, Y., Shi, J., Guo, W. and Zhou, D., 2019. <a href="https://ascopubs.org/doi/full/10.1200/JCO.18.02184">Neoadjuvant three-dimensional conformal radiotherapy for resectable hepatocellular carcinoma with portal vein tumor thrombus: a randomized, open-label, multicenter controlled study.</a> <i>Journal of Clinical Oncology</i>, <i>37</i>(24), pp.2141-2151.</li> <li>Stein, J.E., Lipson, E.J., Cottrell, T.R., Forde, P.M., Anders, R.A., Cimino-Mathews, A., Thompson, E.D., Allaf, M.E., Yarchoan, M., Feliciano, J. and Wang, H., 2020. <a href="https://aacrjournals.org/clincancerres/article/26/3/545/83188/Pan-Tumor-Pathologic-Scoring-of-Response-to-PD-L-1">Pan-tumor pathologic scoring of response to PD-(L) 1 blockade.</a> <i>Clinical Cancer Research</i>, <i>26</i>(3), pp.545-551.</li> <li>Lewis, A.R., Padula, C.A., McKinney, J.M. and Toskich, B.B., 2019, October. <a href="https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0039-1697641">Ablation plus transarterial embolic therapy for hepatocellular carcinoma larger than 3 cm: science, evidence, and future directions.</a> In <i>Seminars in Interventional Radiology</i> (Vol. 36, No. 04, pp. 303-309). Thieme Medical Publishers.</li> </ol> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Top Experts on “<b style="color:#000;font-size:22px;">hepatocellular carcinoma</b>“</h2> </div> </div><div class="author-main"><div id="results_author"></div><div style="text-align: center;"><a class="register-button" href="https://cancerscience.net/expert-search" target="_blank" rel="noopener">Find experts on any field</a></div></div><div class="inside-article" style="background: none;border: none;box-shadow: none;margin-top: -70px;"> <style> .author-block { padding: 15px; margin-bottom: 10px; text-align: left; font-size: 15px; line-height: 1.2; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .author-block h3 { margin: 0 0 10px; color: #227cdc; } .author-block p { margin: 5px 0; } .author-b { display: flex; justify-content: space-between; flex-wrap: wrap; margin-bottom:10px; } .author-b .ainfo { flex: 1 1 30%; box-sizing: border-box; text-align: left; background: #dcdcdc; padding: 7px 14px; border-radius: 5px; margin-top: 3px; margin-right: 10px; } @media (max-width: 768px) { .author-b .ainfo { flex: 1 1 100%; margin: 10px 0; } } </style> <script> function displayResults_author(authors) { var resultsContainer = document.getElementById('results_author'); resultsContainer.innerHTML = ''; if (!authors || Object.keys(authors).length === 0) { resultsContainer.innerHTML = '<p>No authors found.</p>'; return; } Object.values(authors).slice(0, 10).forEach(author => { var authorBlock = document.createElement('div'); authorBlock.className = 'author-block'; var author_name=author.name; let key_replace = author_name.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); var authorHTML = ` <h3><a href="https://cancerscience.net/author/index/${key_replace}\/${author.aid}" target="_blank" title="${author.name}">${author.name}</a></h3> <div class="author-b"> <div class="ainfo"><strong>H-Index:</strong> ${author.hindex}</div> <div class="ainfo"><strong>Publication Count:</strong> ${author.paper_count}</div> <div class="ainfo"><strong>Citation Count:</strong> ${author.citation_count}</div> </div> <p><strong>Affiliation:</strong> ${author.affiliation}</p> `; authorBlock.innerHTML = authorHTML; resultsContainer.appendChild(authorBlock); }); } function displayKeywordAuthors(keywords) { var resultsContainer = document.getElementById('keyword-authors'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach(key => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://cancerscience.net/expert-search/index/${key_replace}" target="_blank" title="${key}">${key}</a>`; }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var authors_data = { "6sf2KowBWBy50K-rn5AK": { "aid": "6sf2KowBWBy50K-rn5AK", "name": "R. Jain", "citation_count": 162773, "hindex": 190, "paper_count": 980, "affiliation": "Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. ", "email": "jain@steele.mgh.harvard.edu", "slug_tail": "r-jain" }, "sTfcKowBWBy50K-r0FW6": { "aid": "sTfcKowBWBy50K-r0FW6", "name": "G. Gores", "citation_count": 80488, "hindex": 157, "paper_count": 949, "affiliation": "Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. ", "email": "gores.gregory@mayo.edu", "slug_tail": "g-gores" }, "7yQHK4wBWBy50K-rqzbr": { "aid": "7yQHK4wBWBy50K-rqzbr", "name": "Shuhong Yu", "citation_count": 80373, "hindex": 155, "paper_count": 808, "affiliation": "Division of Nanomaterials and Chemistry, Hefei National Laboratory for Physical Sciences at Microscale, Collaborative Innovation Center of Suzhou, Nano Science and Technology, Department of Chemistry, University of Science and Technology of China, Hefei 230026 (P.R. China). ", "email": "shyu@ustc.edu.cn", "slug_tail": "shuhong-yu" }, "6-ovK4wBWBy50K-ry_To": { "aid": "6-ovK4wBWBy50K-ry_To", "name": "Zhenan Bao", "citation_count": 86828, "hindex": 148, "paper_count": 708, "affiliation": "Department of Chemical Engineering, Stanford University, 443 Via Ortega, Room 307, Stanford, CA, 94305, USA. ", "email": "zbao@stanford.edu", "slug_tail": "zhenan-bao" }, "76-WK4wBWBy50K-rtjIG": { "aid": "76-WK4wBWBy50K-rtjIG", "name": "Xiaoyuan Chen", "citation_count": 73154, "hindex": 143, "paper_count": 827, "affiliation": "Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland; and ", "email": "shawn.chen@nih.gov", "slug_tail": "xiaoyuan-chen" }, "-GvlKowBWBy50K-rkBRH": { "aid": "-GvlKowBWBy50K-rkBRH", "name": "S. Lowe", "citation_count": 95260, "hindex": 140, "paper_count": 542, "affiliation": "Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York. ", "email": "lowes@mskcc.org", "slug_tail": "s-lowe" }, "aUm_K4wBWBy50K-r3EQe": { "aid": "aUm_K4wBWBy50K-r3EQe", "name": "J. Llovet", "citation_count": 100592, "hindex": 137, "paper_count": 577, "affiliation": "Liver Cancer Translational Research Laboratory, Barcelona-Cl\u00ednic Liver Cancer Group, Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Hospital Cl\u00ednic de Barcelona, Universitat de Barcelona (UB), Barcelona, Catalonia, Spain; Mount Sinai Liver Cancer Program, Division of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, Madison avenue 1425, 11F-70, Box 1123, 10029 New York, USA; Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats, Barcelona, Catalonia, Spain. ", "email": "Josep.Llovet@mssm.edu", "slug_tail": "j-llovet" }, "ub_ZK4wBWBy50K-rq7Uh": { "aid": "ub_ZK4wBWBy50K-rq7Uh", "name": "J. Allison", "citation_count": 87370, "hindex": 137, "paper_count": 570, "affiliation": "Program in Immunology, Howard Hughes Medical Institute, and Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ", "email": "JAllison@mdanderson.org", "slug_tail": "j-allison" }, "nvdpK4wBWBy50K-rDGPE": { "aid": "nvdpK4wBWBy50K-rDGPE", "name": "S. Zeuzem", "citation_count": 94125, "hindex": 136, "paper_count": 1757, "affiliation": "Department of Medicine 1, Goethe University Hospital, Theodor-Stern-Kai 7, Frankfurt 60590, Germany. ", "email": "zeuzem@em.uni-frankfurt.de", "slug_tail": "s-zeuzem" }, "1PWrK4wBWBy50K-rFxH2": { "aid": "1PWrK4wBWBy50K-rFxH2", "name": "X. Chen", "citation_count": 91405, "hindex": 135, "paper_count": 2966, "affiliation": "Department of Chemistry, University of California, Davis, CA 95616, USA. ", "email": "chen@chem.ucdavis.edu", "slug_tail": "x-chen" }, "_Q9tK4wBWBy50K-rdkPV": { "aid": "_Q9tK4wBWBy50K-rdkPV", "name": "H. El\u2010Serag", "citation_count": 74821, "hindex": 132, "paper_count": 999, "affiliation": "Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. ", "email": "hasheme@bcm.edu", "slug_tail": "h-el-serag" }, "BBzvK4wBWBy50K-rBznJ": { "aid": "BBzvK4wBWBy50K-rBznJ", "name": "P. Marcellin", "citation_count": 69735, "hindex": 129, "paper_count": 978, "affiliation": "H\u00f4pital Beaujon, University Paris-Diderot, Clichy, France. ", "email": "patrick.marcellin@bjn.aphp.fr", "slug_tail": "p-marcellin" }, "Ap8hK4wBWBy50K-r0VND": { "aid": "Ap8hK4wBWBy50K-r0VND", "name": "H. Friess", "citation_count": 72031, "hindex": 129, "paper_count": 1487, "affiliation": "Department of Surgery, TUM School of Medicine, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany, ", "email": "helmut.friess@tum.de", "slug_tail": "h-friess" }, "7JrtKowBWBy50K-r6DCt": { "aid": "7JrtKowBWBy50K-r6DCt", "name": "D. Brenner", "citation_count": 50157, "hindex": 129, "paper_count": 591, "affiliation": "School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, 92093 California, United States. ", "email": "dbrenner@ucsd.edu", "slug_tail": "d-brenner" }, "5QGuK4wBWBy50K-rqczx": { "aid": "5QGuK4wBWBy50K-rqczx", "name": "R. Kaufman", "citation_count": 70430, "hindex": 127, "paper_count": 429, "affiliation": "Degenerative Diseases Program, Sanford_Burnham_Prebys Medical Discovery Institute, 92037, La Jolla, CA, USA. ", "email": "rkaufman@sbpdiscovery.org", "slug_tail": "r-kaufman" }, "f1xFK4wBWBy50K-rcEMj": { "aid": "f1xFK4wBWBy50K-rcEMj", "name": "S. Friedman", "citation_count": 65238, "hindex": 124, "paper_count": 560, "affiliation": "Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ", "email": "scott.friedman@mssm.edu", "slug_tail": "s-friedman" }, "i_BnK4wBWBy50K-rFkWF": { "aid": "i_BnK4wBWBy50K-rFkWF", "name": "T. Pawlik", "citation_count": 66233, "hindex": 123, "paper_count": 2209, "affiliation": "Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD. ", "email": "tpawlik1@jhmi.edu", "slug_tail": "t-pawlik" }, "p14SK4wBWBy50K-rW9v_": { "aid": "p14SK4wBWBy50K-rW9v_", "name": "J. Bruix", "citation_count": 92749, "hindex": 123, "paper_count": 579, "affiliation": "Barcelona Clinic Liver Cancer Group, Liver Unit, Hospital Clinic, IDIBAPS, University of Barcelona, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBEREHD), Barcelona, Spain. ", "email": "jbruix@clinic.ub.es", "slug_tail": "j-bruix" }, "5cGbK4wBWBy50K-ryKmm": { "aid": "5cGbK4wBWBy50K-ryKmm", "name": "J. Vauthey", "citation_count": 69796, "hindex": 123, "paper_count": 950, "affiliation": "Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. ", "email": "jvauthey@mdanderson.org", "slug_tail": "j-vauthey" }, "tFF_K4wBWBy50K-rMvav": { "aid": "tFF_K4wBWBy50K-rMvav", "name": "C. Harris", "citation_count": 72643, "hindex": 122, "paper_count": 753, "affiliation": "Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. ", "email": "harrisc@mail.nih.gov", "slug_tail": "c-harris" }, "DBHtK4wBWBy50K-rAWk_": { "aid": "DBHtK4wBWBy50K-rAWk_", "name": "Lieping Chen", "citation_count": 78305, "hindex": 122, "paper_count": 513, "affiliation": "Laboratory of Immunotherapy, Sun Yet-Sen University, Guangzhou, Guangdong, People's Republic of China. ", "email": "lieping.chen@yale.edu", "slug_tail": "lieping-chen" }, "gjndKowBWBy50K-rMtQ-": { "aid": "gjndKowBWBy50K-rMtQ-", "name": "M. Merad", "citation_count": 64387, "hindex": 119, "paper_count": 507, "affiliation": "Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. ", "email": "miriam.merad@mssm.edu", "slug_tail": "m-merad" }, "bVwSK4wBWBy50K-rBd2j": { "aid": "bVwSK4wBWBy50K-rBd2j", "name": "P. Worley", "citation_count": 50904, "hindex": 119, "paper_count": 352, "affiliation": "Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA. ", "email": "pworley@jhmi.edu", "slug_tail": "p-worley" }, "Gu6qK4wBWBy50K-rA-p2": { "aid": "Gu6qK4wBWBy50K-rA-p2", "name": "W. Jarnagin", "citation_count": 53038, "hindex": 119, "paper_count": 823, "affiliation": "Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. ", "email": "jarnagiw@mskcc.org", "slug_tail": "w-jarnagin" }, "-HhMK4wBWBy50K-r0GMH": { "aid": "-HhMK4wBWBy50K-r0GMH", "name": "R. Busuttil", "citation_count": 50427, "hindex": 116, "paper_count": 1081, "affiliation": "Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine, University of California at Los Angeles, The Dumont-UCLA Transplant Center, 757 Westwood Blvd, Suite 8236, Los Angeles, CA 90095, USA. ", "email": "rbusuttil@mednet.ucla.edu", "slug_tail": "r-busuttil" }, "mH6JK4wBWBy50K-rolrC": { "aid": "mH6JK4wBWBy50K-rolrC", "name": "T. Therneau", "citation_count": 54369, "hindex": 115, "paper_count": 523, "affiliation": "Department of Quantitative Health Sciences, Mayo Clinic 200 1st St. SW, Rochester, MN 55905. ", "email": "therneau@mayo.edu", "slug_tail": "t-therneau" }, "zLjYK4wBWBy50K-rRnPx": { "aid": "zLjYK4wBWBy50K-rRnPx", "name": "M. Kudo", "citation_count": 71681, "hindex": 115, "paper_count": 1811, "affiliation": "Department of Gastroenterology and Hepatology, Kinki University School of Medicine, 377-2, Ohno-Higashi, Osaka-Sayama, 589-8511, Osaka, Japan. ", "email": "m-kudo@med.kindai.ac.jp", "slug_tail": "m-kudo" }, "LwQBK4wBWBy50K-r6TBp": { "aid": "LwQBK4wBWBy50K-r6TBp", "name": "M. Gershwin", "citation_count": 45566, "hindex": 114, "paper_count": 940, "affiliation": "Division of Rheumatology, Allergy, and Clinical Immunology, University of California at Davis School of Medicine, Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Suite 6510, Davis, CA, 95616, USA. ", "email": "megershwin@ucdavis.edu", "slug_tail": "m-gershwin" }, "FncXK4wBWBy50K-rhM2D": { "aid": "FncXK4wBWBy50K-rhM2D", "name": "K. Chayama", "citation_count": 61474, "hindex": 113, "paper_count": 1909, "affiliation": "Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan Liver Research Project Center, Hiroshima University, Hiroshima, Japan Laboratory for Digestive Diseases, Center for Genomic Medicine, The Institute of Physical and Chemical Research (RIKEN), Hiroshima, Japan ", "email": "chayama@hiroshima-u.ac.jp", "slug_tail": "k-chayama" }, "h1ZEK4wBWBy50K-rAIlZ": { "aid": "h1ZEK4wBWBy50K-rAIlZ", "name": "A. Heck", "citation_count": 53028, "hindex": 113, "paper_count": 985, "affiliation": "Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands. ", "email": "a.j.r.heck@uu.nl", "slug_tail": "a-heck" }, "o4TMK4wBWBy50K-rVrwr": { "aid": "o4TMK4wBWBy50K-rVrwr", "name": "C. Sirlin", "citation_count": 43391, "hindex": 112, "paper_count": 625, "affiliation": "Liver Imaging Group, Department of Radiology, University of California, San Diego, 9500 Gilman Drive, San Diego, CA, 92093-0888, USA. ", "email": "csirlin@ucsd.edu", "slug_tail": "c-sirlin" }, "KdH4KowBWBy50K-rUet0": { "aid": "KdH4KowBWBy50K-rUet0", "name": "F. Ginhoux", "citation_count": 57584, "hindex": 112, "paper_count": 467, "affiliation": "Singapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Immunos Building, Level 4, Singapore 138648, Singapore. ", "email": "florent_ginhoux@immunol.a-star.edu.sg", "slug_tail": "f-ginhoux" }, "SA2wK4wBWBy50K-rlXgK": { "aid": "SA2wK4wBWBy50K-rlXgK", "name": "V. Miller", "citation_count": 75332, "hindex": 112, "paper_count": 956, "affiliation": "Foundation Medicine, Inc., 150 Second Street, Cambridge, MA, USA. ", "email": "vmiller@foundationmedicine.com", "slug_tail": "v-miller" }, "PBPtK4wBWBy50K-rRAsQ": { "aid": "PBPtK4wBWBy50K-rRAsQ", "name": "L. Birnbaumer", "citation_count": 44912, "hindex": 110, "paper_count": 712, "affiliation": "Neurobiology Laboratory, National Institute of Environmental Research, Research Triangle Park, NC, 27009, USA. ", "email": "Birnbau1@gmail.com", "slug_tail": "l-birnbaumer" }, "YajUK4wBWBy50K-rewD8": { "aid": "YajUK4wBWBy50K-rewD8", "name": "M. Febbraio", "citation_count": 38823, "hindex": 110, "paper_count": 441, "affiliation": "Cellular and Molecular Metabolism Laboratory, Baker IDI Heart & Diabetes Institute, Melbourne, VIC, Australia; Diabetes & Metabolism Division, Garvan Institute of Medical Research, NSW, Australia. ", "email": "m.febbraio@garvan.org.au", "slug_tail": "m-febbraio" }, "06jwKowBWBy50K-rpl28": { "aid": "06jwKowBWBy50K-rpl28", "name": "Chien-Jen Chen", "citation_count": 54083, "hindex": 109, "paper_count": 636, "affiliation": "Genomics Research Center, Academia Sinica, Taipei, Taiwan. ", "email": "chencj@gate.sinica.edu.tw", "slug_tail": "chien-jen-chen" }, "FqyWK4wBWBy50K-rCyjh": { "aid": "FqyWK4wBWBy50K-rCyjh", "name": "C. Deng", "citation_count": 47340, "hindex": 109, "paper_count": 346, "affiliation": "From the Cancer Center, Faculty of Health Sciences and ", "email": "cxdeng@umac.mo", "slug_tail": "c-deng" }, "T9UrK4wBWBy50K-r6KG8": { "aid": "T9UrK4wBWBy50K-r6KG8", "name": "M. Uhl\u00e9n", "citation_count": 69734, "hindex": 109, "paper_count": 909, "affiliation": "Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden ", "email": "mathias.uhlen@scilifelab.se", "slug_tail": "m-uhlen" }, "dTB1K4wBWBy50K-rsBNs": { "aid": "dTB1K4wBWBy50K-rsBNs", "name": "J. Goedert", "citation_count": 53467, "hindex": 108, "paper_count": 600, "affiliation": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. ", "email": "JamesJGoedert@gmail.com", "slug_tail": "j-goedert" }, "q2HEK4wBWBy50K-r32s7": { "aid": "q2HEK4wBWBy50K-r32s7", "name": "Leaf Huang", "citation_count": 39937, "hindex": 108, "paper_count": 491, "affiliation": "Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. ", "email": "Leafh@email.unc.edu", "slug_tail": "leaf-huang" }, "MlRDK4wBWBy50K-rut9y": { "aid": "MlRDK4wBWBy50K-rut9y", "name": "P. Sham", "citation_count": 84190, "hindex": 106, "paper_count": 881, "affiliation": "Department of Psychiatry, University of Hong Kong, Hong Kong, P.R. China; Centre for Genomic Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, P.R. China. ", "email": "pcsham@hku.hk", "slug_tail": "p-sham" }, "QbZZK4wBWBy50K-reyOh": { "aid": "QbZZK4wBWBy50K-reyOh", "name": "D. Nagorney", "citation_count": 41991, "hindex": 105, "paper_count": 543, "affiliation": "Department of Subspecialty General Surgery, Mayo Clinic, Rochester, MN, 55905, USA. ", "email": "Nagorney.david@mayo.edu", "slug_tail": "d-nagorney" }, "TIQbK4wBWBy50K-r0L5t": { "aid": "TIQbK4wBWBy50K-r0L5t", "name": "A. Gasbarrini", "citation_count": 53096, "hindex": 105, "paper_count": 2257, "affiliation": "Division of Internal Medicine and Gastroenterology, Gemelli University Hospital, Catholic University of Sacred Heart, Italy. ", "email": "agasbarrini@rm.unicatt.it", "slug_tail": "a-gasbarrini" }, "Gf0AK4wBWBy50K-rt6hL": { "aid": "Gf0AK4wBWBy50K-rt6hL", "name": "H. Pitt", "citation_count": 38708, "hindex": 105, "paper_count": 621, "affiliation": "Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA; Temple University Health System, Philadelphia, PA. ", "email": "Henry.Pitt@tuhs.temple.edu", "slug_tail": "h-pitt" }, "KOIuK4wBWBy50K-rbQ6o": { "aid": "KOIuK4wBWBy50K-rbQ6o", "name": "W. Stetler-Stevenson", "citation_count": 40082, "hindex": 104, "paper_count": 327, "affiliation": "Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892. ", "email": "sstevenw@mail.nih.gov", "slug_tail": "w-stetler-stevenson" }, "I7cmK4wBWBy50K-rjSe6": { "aid": "I7cmK4wBWBy50K-rjSe6", "name": "Y. Liaw", "citation_count": 40768, "hindex": 104, "paper_count": 617, "affiliation": "Liver Research Unit, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan. ", "email": "liveryfl@gmail.com", "slug_tail": "y-liaw" }, "TXzKK4wBWBy50K-rQlC7": { "aid": "TXzKK4wBWBy50K-rQlC7", "name": "E. Vicaut", "citation_count": 43544, "hindex": 104, "paper_count": 810, "affiliation": "Clinical research unit, h\u00f4pital Fernand-Widal, AP-HP, 200, rue du Faubourg-Saint-Denis, 75475 Paris, France. ", "email": "eric.vicaut@aphp.fr", "slug_tail": "e-vicaut" }, "7s-gK4wBWBy50K-rtvvy": { "aid": "7s-gK4wBWBy50K-rtvvy", "name": "F. Zoulim", "citation_count": 41708, "hindex": 103, "paper_count": 827, "affiliation": "INSERM U1052-Cancer Research Center of Lyon (CRCL), 69008 Lyon, France; University of Lyon, UMR_S1052, CRCL, 69008 Lyon, France; Department of Hepatology, Croix Rousse Hospital, Hospices Civils de Lyon, France. ", "email": "fabien.zoulim@inserm.fr", "slug_tail": "f-zoulim" }, "7MddK4wBWBy50K-rUDUl": { "aid": "7MddK4wBWBy50K-rUDUl", "name": "Xuetao Cao", "citation_count": 38621, "hindex": 103, "paper_count": 605, "affiliation": "National Key Laboratory of Medical Molecular Biology, Department of Immunology, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China; and National Key Laboratory of Medical Immunology and Institute of Immunology, Second Military Medical University, Shanghai 200433, China ", "email": "caoxt@immunol.org", "slug_tail": "xuetao-cao" }, "ZlJDK4wBWBy50K-rMDqV": { "aid": "ZlJDK4wBWBy50K-rMDqV", "name": "J. Pawlotsky", "citation_count": 41206, "hindex": 102, "paper_count": 742, "affiliation": "INSERM U955, Team Viruses, Hepatology, Cancer, Cr\u00e9teil, France; National Reference Center for Viral Hepatitis B, C and Delta, Department of Virology, H\u00f4pital Henri Mondor, Universit\u00e9 Paris-Est, Cr\u00e9teil, France. ", "email": "jean-michel.pawlotsky@aphp.fr", "slug_tail": "j-pawlotsky" } }; //console.log(authors_data); displayResults_author(authors_data); var keywordsArray = ["Hepatocellular carcinoma","radiotherapy","stereotactic body radiation therapy","image-guided radiotherapy","neoadjuvant radiotherapy","liver cancer","portal vein tumor thrombus","transarterial chemoembolization"]; displayKeywordAuthors(keywordsArray); </script></p> </div> <footer class="entry-meta" aria-label="Entry meta"> <span class="cat-links"><span class="gp-icon icon-categories"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M0 112c0-26.51 21.49-48 48-48h110.014a48 48 0 0143.592 27.907l12.349 26.791A16 16 0 00228.486 128H464c26.51 0 48 21.49 48 48v224c0 26.51-21.49 48-48 48H48c-26.51 0-48-21.49-48-48V112z" /></svg></span><span class="screen-reader-text">Categories </span><a href="https://cancerscience.net/archive/category/hepatocellular-carcinoma/" rel="category tag">hepatocellular carcinoma</a></span> <span class="tags-links"><span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"/><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z" /></svg></span><span class="screen-reader-text">Tags </span><a href="https://cancerscience.net/archive/tag/hepatocellular-carcinoma/" rel="tag">Hepatocellular carcinoma</a>, <a href="https://cancerscience.net/archive/tag/image-guided-radiotherapy/" rel="tag">image-guided radiotherapy</a>, <a href="https://cancerscience.net/archive/tag/liver-cancer/" rel="tag">liver cancer</a>, <a href="https://cancerscience.net/archive/tag/neoadjuvant-radiotherapy/" rel="tag">neoadjuvant radiotherapy</a>, <a href="https://cancerscience.net/archive/tag/portal-vein-tumor-thrombus/" rel="tag">portal vein tumor thrombus</a>, <a href="https://cancerscience.net/archive/tag/radiotherapy/" rel="tag">radiotherapy</a>, <a href="https://cancerscience.net/archive/tag/stereotactic-body-radiation-therapy/" rel="tag">stereotactic body radiation therapy</a>, <a href="https://cancerscience.net/archive/tag/transarterial-chemoembolization/" rel="tag">transarterial chemoembolization</a></span> <nav id="nav-below" class="post-navigation" aria-label="Posts"> <div class="nav-previous"><span class="gp-icon icon-arrow-left"><svg viewBox="0 0 192 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em" fill-rule="evenodd" clip-rule="evenodd" stroke-linejoin="round" stroke-miterlimit="1.414"><path d="M178.425 138.212c0 2.265-1.133 4.813-2.832 6.512L64.276 256.001l111.317 111.277c1.7 1.7 2.832 4.247 2.832 6.513 0 2.265-1.133 4.813-2.832 6.512L161.43 394.46c-1.7 1.7-4.249 2.832-6.514 2.832-2.266 0-4.816-1.133-6.515-2.832L16.407 262.514c-1.699-1.7-2.832-4.248-2.832-6.513 0-2.265 1.133-4.813 2.832-6.512l131.994-131.947c1.7-1.699 4.249-2.831 6.515-2.831 2.265 0 4.815 1.132 6.514 2.831l14.163 14.157c1.7 1.7 2.832 3.965 2.832 6.513z" fill-rule="nonzero" /></svg></span><span class="prev"><a href="https://cancerscience.net/archive/cancer/integrins-in-cancer-from-cell-adhesion-to-metastasis/" rel="prev">Integrins in Cancer: From Cell Adhesion to Metastasis</a></span></div><div class="nav-next"><span class="gp-icon icon-arrow-right"><svg viewBox="0 0 192 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em" fill-rule="evenodd" clip-rule="evenodd" stroke-linejoin="round" stroke-miterlimit="1.414"><path d="M178.425 256.001c0 2.266-1.133 4.815-2.832 6.515L43.599 394.509c-1.7 1.7-4.248 2.833-6.514 2.833s-4.816-1.133-6.515-2.833l-14.163-14.162c-1.699-1.7-2.832-3.966-2.832-6.515 0-2.266 1.133-4.815 2.832-6.515l111.317-111.316L16.407 144.685c-1.699-1.7-2.832-4.249-2.832-6.515s1.133-4.815 2.832-6.515l14.163-14.162c1.7-1.7 4.249-2.833 6.515-2.833s4.815 1.133 6.514 2.833l131.994 131.993c1.7 1.7 2.832 4.249 2.832 6.515z" fill-rule="nonzero" /></svg></span><span class="next"><a href="https://cancerscience.net/archive/non-hodgkins-lymphoma/advancements-in-immunotherapy-for-lymphoma-a-focus-on-non-hodgkins-lymphoma/" rel="next">Advancements in Immunotherapy for Lymphoma: A Focus on Non-Hodgkin’s Lymphoma</a></span></div> </nav> </footer> </div> </article> </main> </div> <div class="widget-area sidebar is-right-sidebar" id="right-sidebar"> <div class="inside-right-sidebar"> <aside id="block-2" class="widget inner-padding widget_block widget_search"><form role="search" method="get" action="https://cancerscience.net/archive/" class="wp-block-search__button-outside wp-block-search__text-button wp-block-search" ><label class="wp-block-search__label" for="wp-block-search__input-1" >Search</label><div class="wp-block-search__inside-wrapper " ><input class="wp-block-search__input" id="wp-block-search__input-1" placeholder="" value="" type="search" name="s" required /><button aria-label="Search" class="wp-block-search__button wp-element-button" type="submit" >Search</button></div></form></aside><aside id="block-3" class="widget inner-padding widget_block"><div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"><h2 class="wp-block-heading">Recent Posts</h2><ul class="wp-block-latest-posts__list wp-block-latest-posts"><li><a class="wp-block-latest-posts__post-title" href="https://cancerscience.net/archive/radiation-induced-malignancies/understanding-radiation-induced-malignancies-a-two-edged-sword/">Understanding Radiation-Induced Malignancies: A Two-Edged Sword?</a></li> <li><a class="wp-block-latest-posts__post-title" href="https://cancerscience.net/archive/lung-cancer/tuberculosis-and-lung-cancer-a-dangerous-synergy/">Tuberculosis and Lung Cancer: A Dangerous Synergy</a></li> <li><a class="wp-block-latest-posts__post-title" href="https://cancerscience.net/archive/cancer/integrins-in-cancer-from-cell-adhesion-to-metastasis-2/">Integrins in Cancer: From Cell Adhesion to Metastasis</a></li> <li><a class="wp-block-latest-posts__post-title" href="https://cancerscience.net/archive/non-hodgkins-lymphoma/advancements-in-immunotherapy-for-lymphoma-a-focus-on-non-hodgkins-lymphoma/">Advancements in Immunotherapy for Lymphoma: A Focus on Non-Hodgkin’s Lymphoma</a></li> <li><a class="wp-block-latest-posts__post-title" href="https://cancerscience.net/archive/hepatocellular-carcinoma/role-of-radiotherapy-in-treating-hepatocellular-carcinoma/">Role of Radiotherapy in Treating Hepatocellular Carcinoma</a></li> </ul></div></div></aside><aside id="block-4" class="widget inner-padding widget_block"><div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"><h2 class="wp-block-heading">Recent Comments</h2><div class="no-comments wp-block-latest-comments">No comments to show.</div></div></div></aside> </div> </div> </div> </div> <div class="site-footer footer-bar-active footer-bar-align-right"> <footer class="site-info" aria-label="Site" itemtype="https://schema.org/WPFooter" itemscope> <div class="inside-site-info grid-container"> <div class="footer-bar"> <aside id="nav_menu-3" class="widget inner-padding widget_nav_menu"><div class="menu-footer-menu-container"><ul id="menu-footer-menu" class="menu"><li id="menu-item-92" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-92"><a href="https://cancerscience.net/archive/privacy-policy/">Privacy Policy</a></li> <li id="menu-item-89" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-89"><a href="https://cancerscience.net/archive/disclaimer/">Disclaimer</a></li> <li id="menu-item-90" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-90"><a href="https://cancerscience.net/archive/terms-and-conditions/">Terms and Conditions</a></li> <li id="menu-item-103" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-103"><a href="https://cancerscience.net/archive/contact-us/">Contact us</a></li> <li id="menu-item-116" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-116"><a href="https://cancerscience.net/archive/about-us/">About us</a></li> </ul></div></aside> </div> <div class="copyright-bar"> © 2024 Cancer Science </div> </div> </footer> </div> <script id="generate-a11y">!function(){"use strict";if("querySelector"in document&&"addEventListener"in window){var e=document.body;e.addEventListener("mousedown",function(){e.classList.add("using-mouse")}),e.addEventListener("keydown",function(){e.classList.remove("using-mouse")})}}();</script> <div class="gp-modal gp-search-modal" id="gp-search"> <div class="gp-modal__overlay" tabindex="-1" data-gpmodal-close> <div class="gp-modal__container"> <form role="search" method="get" class="search-modal-form" action="https://cancerscience.net/archive/"> <label for="search-modal-input" class="screen-reader-text">Search for:</label> <div class="search-modal-fields"> <input id="search-modal-input" type="search" class="search-field" placeholder="Search …" value="" name="s" /> <button aria-label="Search"><span class="gp-icon icon-search"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path fill-rule="evenodd" clip-rule="evenodd" d="M208 48c-88.366 0-160 71.634-160 160s71.634 160 160 160 160-71.634 160-160S296.366 48 208 48zM0 208C0 93.125 93.125 0 208 0s208 93.125 208 208c0 48.741-16.765 93.566-44.843 129.024l133.826 134.018c9.366 9.379 9.355 24.575-.025 33.941-9.379 9.366-24.575 9.355-33.941-.025L337.238 370.987C301.747 399.167 256.839 416 208 416 93.125 416 0 322.875 0 208z" /></svg></span></button> </div> </form> </div> </div> </div> <script src="https://cancerscience.net/archive/wp-content/plugins/gp-premium/menu-plus/functions/js/sticky.min.js?ver=2.4.1" id="generate-sticky-js"></script> <!--[if lte IE 11]> <script src="https://cancerscience.net/archive/wp-content/themes/generatepress/assets/js/classList.min.js?ver=3.4.0" id="generate-classlist-js"></script> <![endif]--> <script id="generate-menu-js-extra"> var generatepressMenu = {"toggleOpenedSubMenus":"1","openSubMenuLabel":"Open Sub-Menu","closeSubMenuLabel":"Close Sub-Menu"}; </script> <script src="https://cancerscience.net/archive/wp-content/themes/generatepress/assets/js/menu.min.js?ver=3.4.0" id="generate-menu-js"></script> <script src="https://cancerscience.net/archive/wp-content/themes/generatepress/assets/dist/modal.js?ver=3.4.0" id="generate-modal-js"></script> </body> </html>