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.ubermenu-target{ padding-left:25px; } .ubermenu-vertical.ubermenu-invert .ubermenu-item > .ubermenu-target > .ubermenu-sub-indicator { right:auto; left:10px; transform:rotate(90deg); } .ubermenu-vertical.ubermenu-invert .ubermenu-item > .ubermenu-submenu-drop.ubermenu-submenu-type-flyout, .ubermenu-vertical.ubermenu-invert .ubermenu-submenu-type-flyout > .ubermenu-item > .ubermenu-submenu-drop { right: 100%; left: auto; } .ubermenu-responsive-toggle{ display:none; } } @media screen and (max-width: 1180px){ .ubermenu-responsive-toggle, .ubermenu-sticky-toggle-wrapper { display: block; } .ubermenu-responsive{ width:100%; max-height:600px; visibility:visible; overflow:visible; -webkit-transition:max-height 1s ease-in; transition:max-height .3s ease-in; } .ubermenu-responsive.ubermenu-mobile-accordion:not(.ubermenu-mobile-modal):not(.ubermenu-in-transition):not(.ubermenu-responsive-collapse){ max-height:none; } .ubermenu-responsive.ubermenu-items-align-center{ text-align:left; } .ubermenu-responsive.ubermenu{ margin:0; } .ubermenu-responsive.ubermenu .ubermenu-nav{ display:block; } .ubermenu-responsive.ubermenu-responsive-nocollapse, .ubermenu-repsonsive.ubermenu-no-transitions{ display:block; max-height:none; } .ubermenu-responsive.ubermenu-responsive-collapse{ max-height:none; visibility:visible; overflow:visible; } .ubermenu-responsive.ubermenu-responsive-collapse{ max-height:0; overflow:hidden !important; visibility:hidden; } .ubermenu-responsive.ubermenu-in-transition, .ubermenu-responsive.ubermenu-in-transition .ubermenu-nav{ overflow:hidden !important; visibility:visible; } .ubermenu-responsive.ubermenu-responsive-collapse:not(.ubermenu-in-transition){ border-top-width:0; border-bottom-width:0; } .ubermenu-responsive.ubermenu-responsive-collapse .ubermenu-item .ubermenu-submenu{ display:none; } .ubermenu-responsive .ubermenu-item-level-0{ width:50%; } .ubermenu-responsive.ubermenu-responsive-single-column .ubermenu-item-level-0{ float:none; clear:both; width:100%; } .ubermenu-responsive .ubermenu-item.ubermenu-item-level-0 > .ubermenu-target{ border:none; box-shadow:none; } .ubermenu-responsive .ubermenu-item.ubermenu-has-submenu-flyout{ position:static; } .ubermenu-responsive.ubermenu-sub-indicators .ubermenu-submenu-type-flyout .ubermenu-has-submenu-drop > .ubermenu-target > .ubermenu-sub-indicator{ transform:rotate(0); right:10px; left:auto; } .ubermenu-responsive .ubermenu-nav .ubermenu-item .ubermenu-submenu.ubermenu-submenu-drop{ width:100%; min-width:100%; max-width:100%; top:auto; left:0 !important; } .ubermenu-responsive.ubermenu-has-border .ubermenu-nav .ubermenu-item .ubermenu-submenu.ubermenu-submenu-drop{ left: -1px !important; /* For borders */ } .ubermenu-responsive .ubermenu-submenu.ubermenu-submenu-type-mega > .ubermenu-item.ubermenu-column{ min-height:0; border-left:none; float:left; /* override left/center/right content alignment */ display:block; } .ubermenu-responsive .ubermenu-item.ubermenu-active > .ubermenu-submenu.ubermenu-submenu-type-mega{ max-height:none; height:auto;/*prevent overflow scrolling since android is still finicky*/ overflow:visible; } .ubermenu-responsive.ubermenu-transition-slide .ubermenu-item.ubermenu-in-transition > .ubermenu-submenu-drop{ max-height:1000px; /* because of slide transition */ } .ubermenu .ubermenu-submenu-type-flyout .ubermenu-submenu-type-mega{ min-height:0; } .ubermenu.ubermenu-responsive .ubermenu-column, .ubermenu.ubermenu-responsive .ubermenu-column-auto{ min-width:50%; } .ubermenu.ubermenu-responsive .ubermenu-autoclear > .ubermenu-column{ clear:none; } .ubermenu.ubermenu-responsive .ubermenu-column:nth-of-type(2n+1){ clear:both; } .ubermenu.ubermenu-responsive .ubermenu-submenu-retractor-top:not(.ubermenu-submenu-retractor-top-2) .ubermenu-column:nth-of-type(2n+1){ clear:none; } .ubermenu.ubermenu-responsive .ubermenu-submenu-retractor-top:not(.ubermenu-submenu-retractor-top-2) .ubermenu-column:nth-of-type(2n+2){ clear:both; } .ubermenu-responsive-single-column-subs .ubermenu-submenu .ubermenu-item { float: none; clear: both; width: 100%; min-width: 100%; } .ubermenu.ubermenu-responsive .ubermenu-tabs, .ubermenu.ubermenu-responsive .ubermenu-tabs-group, .ubermenu.ubermenu-responsive .ubermenu-tab, .ubermenu.ubermenu-responsive .ubermenu-tab-content-panel{ /** TABS SHOULD BE 100% ACCORDION */ width:100%; min-width:100%; max-width:100%; left:0; } .ubermenu.ubermenu-responsive .ubermenu-tabs, .ubermenu.ubermenu-responsive .ubermenu-tab-content-panel{ min-height:0 !important;/* Override Inline Style from JS */ } .ubermenu.ubermenu-responsive .ubermenu-tabs{ z-index:15; } .ubermenu.ubermenu-responsive .ubermenu-tab-content-panel{ z-index:20; } /* Tab Layering */ .ubermenu-responsive .ubermenu-tab{ position:relative; } .ubermenu-responsive .ubermenu-tab.ubermenu-active{ position:relative; z-index:20; } .ubermenu-responsive .ubermenu-tab > .ubermenu-target{ border-width:0 0 1px 0; } .ubermenu-responsive.ubermenu-sub-indicators .ubermenu-tabs > .ubermenu-tabs-group > .ubermenu-tab.ubermenu-has-submenu-drop > .ubermenu-target > .ubermenu-sub-indicator{ transform:rotate(0); right:10px; left:auto; } .ubermenu-responsive .ubermenu-tabs > .ubermenu-tabs-group > .ubermenu-tab > .ubermenu-tab-content-panel{ top:auto; border-width:1px; } .ubermenu-responsive .ubermenu-tab-layout-bottom > .ubermenu-tabs-group{ /*position:relative;*/ } .ubermenu-reponsive .ubermenu-item-level-0 > .ubermenu-submenu-type-stack{ /* Top Level Stack Columns */ position:relative; } .ubermenu-responsive .ubermenu-submenu-type-stack .ubermenu-column, .ubermenu-responsive .ubermenu-submenu-type-stack .ubermenu-column-auto{ /* Stack Columns */ width:100%; max-width:100%; } .ubermenu-responsive .ubermenu-item-mini{ /* Mini items */ min-width:0; width:auto; float:left; clear:none !important; } .ubermenu-responsive .ubermenu-item.ubermenu-item-mini > a.ubermenu-target{ padding-left:20px; padding-right:20px; } .ubermenu-responsive .ubermenu-item.ubermenu-hide-mobile{ /* Hiding items */ display:none !important; } .ubermenu-responsive.ubermenu-hide-bkgs .ubermenu-submenu.ubermenu-submenu-bkg-img{ /** Hide Background Images in Submenu */ background-image:none; } .ubermenu.ubermenu-responsive .ubermenu-item-level-0.ubermenu-item-mini{ min-width:0; width:auto; } .ubermenu-vertical .ubermenu-item.ubermenu-item-level-0{ width:100%; } .ubermenu-vertical.ubermenu-sub-indicators .ubermenu-item-level-0.ubermenu-item-has-children > .ubermenu-target > .ubermenu-sub-indicator{ right:10px; left:auto; transform:rotate(0); } .ubermenu-vertical .ubermenu-item.ubermenu-item-level-0.ubermenu-relative.ubermenu-active > .ubermenu-submenu-drop.ubermenu-submenu-align-vertical_parent_item{ top:auto; } .ubermenu.ubermenu-responsive .ubermenu-tabs{ position:static; } /* Tabs on Mobile with mouse (but not click) - leave space to hover off */ .ubermenu:not(.ubermenu-is-mobile):not(.ubermenu-submenu-indicator-closes) .ubermenu-submenu .ubermenu-tab[data-ubermenu-trigger="mouseover"] .ubermenu-tab-content-panel, .ubermenu:not(.ubermenu-is-mobile):not(.ubermenu-submenu-indicator-closes) .ubermenu-submenu .ubermenu-tab[data-ubermenu-trigger="hover_intent"] .ubermenu-tab-content-panel{ margin-left:6%; width:94%; min-width:94%; } /* Sub indicator close visibility */ .ubermenu.ubermenu-submenu-indicator-closes .ubermenu-active > .ubermenu-target > .ubermenu-sub-indicator-close{ display:block; display: flex; align-items: center; justify-content: center; } .ubermenu.ubermenu-submenu-indicator-closes .ubermenu-active > .ubermenu-target > .ubermenu-sub-indicator{ display:none; } .ubermenu .ubermenu-tabs .ubermenu-tab-content-panel{ box-shadow: 0 5px 10px rgba(0,0,0,.075); } /* When submenus and items go full width, move items back to appropriate positioning */ .ubermenu .ubermenu-submenu-rtl { direction: ltr; } /* Fixed position mobile menu */ .ubermenu.ubermenu-mobile-modal{ position:fixed; z-index:9999999; opacity:1; top:0; left:0; width:100%; width:100vw; max-width:100%; max-width:100vw; height:100%; height:calc(100vh - calc(100vh - 100%)); height:-webkit-fill-available; max-height:calc(100vh - calc(100vh - 100%)); max-height:-webkit-fill-available; border:none; box-sizing:border-box; display:flex; flex-direction:column; justify-content:flex-start; overflow-y:auto !important; /* for non-accordion mode */ overflow-x:hidden !important; overscroll-behavior: contain; transform:scale(1); transition-duration:.1s; transition-property: all; } .ubermenu.ubermenu-mobile-modal.ubermenu-mobile-accordion.ubermenu-interaction-press{ overflow-y:hidden !important; } .ubermenu.ubermenu-mobile-modal.ubermenu-responsive-collapse{ overflow:hidden !important; opacity:0; transform:scale(.9); visibility:hidden; } .ubermenu.ubermenu-mobile-modal .ubermenu-nav{ flex:1; overflow-y:auto !important; overscroll-behavior: contain; } .ubermenu.ubermenu-mobile-modal .ubermenu-item-level-0{ margin:0; } .ubermenu.ubermenu-mobile-modal .ubermenu-mobile-close-button{ border:none; background:none; border-radius:0; padding:1em; color:inherit; display:inline-block; text-align:center; font-size:14px; } .ubermenu.ubermenu-mobile-modal .ubermenu-mobile-footer .ubermenu-mobile-close-button{ width: 100%; display: flex; align-items: center; justify-content: center; } .ubermenu.ubermenu-mobile-modal .ubermenu-mobile-footer .ubermenu-mobile-close-button .ubermenu-icon-essential, .ubermenu.ubermenu-mobile-modal .ubermenu-mobile-footer .ubermenu-mobile-close-button .fas.fa-times{ margin-right:.2em; } /* Header/Footer Mobile content */ .ubermenu .ubermenu-mobile-header, .ubermenu .ubermenu-mobile-footer{ display:block; text-align:center; color:inherit; } /* Accordion submenus mobile (single column tablet) */ .ubermenu.ubermenu-responsive-single-column.ubermenu-mobile-accordion.ubermenu-interaction-press .ubermenu-item > .ubermenu-submenu-drop, .ubermenu.ubermenu-responsive-single-column.ubermenu-mobile-accordion.ubermenu-interaction-press .ubermenu-tab > .ubermenu-tab-content-panel{ box-sizing:border-box; border-left:none; border-right:none; box-shadow:none; } .ubermenu.ubermenu-responsive-single-column.ubermenu-mobile-accordion.ubermenu-interaction-press .ubermenu-item.ubermenu-active > .ubermenu-submenu-drop, .ubermenu.ubermenu-responsive-single-column.ubermenu-mobile-accordion.ubermenu-interaction-press .ubermenu-tab.ubermenu-active > .ubermenu-tab-content-panel{ position:static; } /* Accordion indented - remove borders and extra spacing from headers */ .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu.ubermenu-submenu-drop, .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu .ubermenu-item-header.ubermenu-has-submenu-stack > .ubermenu-target{ border:none; } .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu .ubermenu-item-header.ubermenu-has-submenu-stack > .ubermenu-submenu-type-stack{ padding-top:0; } /* Accordion dropdown indentation padding */ .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-item > .ubermenu-target, .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-tab-content-panel .ubermenu-item > .ubermenu-target{ padding-left:calc( var(--ubermenu-accordion-indent) * 2 ); } .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-item > .ubermenu-target, .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-tab-content-panel .ubermenu-tab-content-panel .ubermenu-item > .ubermenu-target{ padding-left:calc( var(--ubermenu-accordion-indent) * 3 ); } .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-item > .ubermenu-target, .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-tab-content-panel .ubermenu-tab-content-panel .ubermenu-tab-content-panel .ubermenu-item > .ubermenu-target{ padding-left:calc( var(--ubermenu-accordion-indent) * 4 ); } /* Reverse Accordion dropdown indentation padding */ .rtl .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-item > .ubermenu-target, .rtl .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-tab-content-panel .ubermenu-item > .ubermenu-target{ padding-left:0; padding-right:calc( var(--ubermenu-accordion-indent) * 2 ); } .rtl .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-item > .ubermenu-target, .rtl .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-tab-content-panel .ubermenu-tab-content-panel .ubermenu-item > .ubermenu-target{ padding-left:0; padding-right:calc( var(--ubermenu-accordion-indent) * 3 ); } .rtl .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-submenu-drop .ubermenu-item > .ubermenu-target, .rtl .ubermenu.ubermenu-mobile-accordion-indent .ubermenu-submenu-drop .ubermenu-tab-content-panel .ubermenu-tab-content-panel .ubermenu-tab-content-panel .ubermenu-item > .ubermenu-target{ padding-left:0; padding-right:calc( var(--ubermenu-accordion-indent) * 4 ); } .ubermenu-responsive-toggle{ display:block; } } @media screen and (max-width: 480px){ .ubermenu.ubermenu-responsive .ubermenu-item-level-0{ width:100%; } .ubermenu.ubermenu-responsive .ubermenu-column, .ubermenu.ubermenu-responsive .ubermenu-column-auto{ min-width:100%; } .ubermenu .ubermenu-autocolumn:not(:first-child), .ubermenu .ubermenu-autocolumn:not(:first-child) .ubermenu-submenu-type-stack{ padding-top:0; } .ubermenu .ubermenu-autocolumn:not(:last-child), .ubermenu .ubermenu-autocolumn:not(:last-child) .ubermenu-submenu-type-stack{ 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data-srcset="https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-200x134.jpg 200w" data-sizes="(max-width: 750px) 100vw, 750px" /><noscript><img width="750" height="500" src="https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="3D artist image of stem cells" decoding="async" fetchpriority="high" srcset="https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-200x134.jpg 200w" sizes="(max-width: 750px) 100vw, 750px" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/news/153814/mechanism-that-controls-reactivation-of-neural-stem-cells-discovered/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="379" data-src="https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-scaled-e1580133365677.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="3D artist image of stem cells" decoding="async" /><noscript><img width="750" height="379" src="https://www.drugtargetreview.com/wp-content/uploads/stem-cells-feature-image-1-scaled-e1580133365677.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="3D artist image of stem cells" decoding="async" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/news/">news</a></span> <h3><a href="https://www.drugtargetreview.com/news/153814/mechanism-that-controls-reactivation-of-neural-stem-cells-discovered/">Mechanism that controls reactivation of neural stem cells discovered</a></h3> <p class="meta">18 October 2024 | By <a href="https://www.drugtargetreview.com/content_author/drug-target-review/" rel="tag">Drug Target Review</a></p> <p class="listOnly">New insights into the role of SUMOylation in the brain could lead to new targeted therapies for neurodegenerative conditions.</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/article/153651/the-hidden-risks-of-over-reliance-on-healthy-donor-material/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="500" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="cell therapy" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-200x134.jpg 200w" data-sizes="(max-width: 750px) 100vw, 750px" /><noscript><img width="750" height="500" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="cell therapy" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-200x134.jpg 200w" sizes="(max-width: 750px) 100vw, 750px" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/article/153651/the-hidden-risks-of-over-reliance-on-healthy-donor-material/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="2560" height="1350" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-scaled.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="cell therapy" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-375x198.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-750x396.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-768x405.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-1536x810.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-2048x1080.jpg 2048w" data-sizes="(max-width: 2560px) 100vw, 2560px" /><noscript><img width="2560" height="1350" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-scaled.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="cell therapy" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-375x198.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-750x396.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-768x405.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-1536x810.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1552585634-2048x1080.jpg 2048w" sizes="(max-width: 2560px) 100vw, 2560px" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/article/">article</a></span> <h3><a href="https://www.drugtargetreview.com/article/153651/the-hidden-risks-of-over-reliance-on-healthy-donor-material/">The hidden risks of over-reliance on healthy donor material</a></h3> <p class="meta">10 October 2024 | By <a href="https://www.drugtargetreview.com/content_author/priya-baraniak-organabio/" rel="tag">Priya Baraniak (OrganaBio)</a></p> <p class="listOnly">Developing cell therapies solely with healthy donor material can jeopardise clinical outcomes, introducing risks ranging from faulty preclinical data to manufacturing failures. We spoke to Priya Baraniak, CBO at OrganaBio, who advocates for early integration of diseased donor material, improved biobanking infrastructure, and cross-industry collaboration to develop more effective, patient-relevant…</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/news/153590/new-link-found-between-immune-system-and-neurological-disease/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="500" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="lewy bodies" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-200x134.jpg 200w" data-sizes="(max-width: 750px) 100vw, 750px" /><noscript><img width="750" height="500" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="lewy bodies" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-200x134.jpg 200w" sizes="(max-width: 750px) 100vw, 750px" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/news/153590/new-link-found-between-immune-system-and-neurological-disease/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="1000" height="563" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="lewy bodies" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937.jpg 1000w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-375x211.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-750x422.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-768x432.jpg 768w" data-sizes="(max-width: 1000px) 100vw, 1000px" /><noscript><img width="1000" height="563" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="lewy bodies" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937.jpg 1000w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-375x211.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-750x422.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_1176504937-768x432.jpg 768w" sizes="(max-width: 1000px) 100vw, 1000px" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/news/">news</a></span> <h3><a href="https://www.drugtargetreview.com/news/153590/new-link-found-between-immune-system-and-neurological-disease/">New link found between immune system and neurological disease</a></h3> <p class="meta">10 October 2024 | By <a href="https://www.drugtargetreview.com/content_author/drug-target-review/" rel="tag">Drug Target Review</a></p> <p class="listOnly">Findings show that alpha-synuclein and an immune response are required for Lewy body formation, in an effect specific to dopaminergic neurons.</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/news/153450/crohns-disease-discovery-of-two-distinct-molecular-subtypes/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="500" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="Crohn's disease" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-200x134.jpg 200w" data-sizes="(max-width: 750px) 100vw, 750px" /><noscript><img width="750" height="500" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="Crohn's disease" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-200x134.jpg 200w" sizes="(max-width: 750px) 100vw, 750px" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/news/153450/crohns-disease-discovery-of-two-distinct-molecular-subtypes/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="2560" height="1440" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-scaled.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="Crohn's disease" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-375x211.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-750x422.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-768x432.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-1536x864.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-2048x1152.jpg 2048w" data-sizes="(max-width: 2560px) 100vw, 2560px" /><noscript><img width="2560" height="1440" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-scaled.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="Crohn's disease" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-375x211.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-750x422.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-768x432.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-1536x864.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2238871645-2048x1152.jpg 2048w" sizes="(max-width: 2560px) 100vw, 2560px" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/news/">news</a></span> <h3><a href="https://www.drugtargetreview.com/news/153450/crohns-disease-discovery-of-two-distinct-molecular-subtypes/">Crohn’s disease: discovery of two distinct molecular subtypes</a></h3> <p class="meta">30 September 2024 | By <a href="https://www.drugtargetreview.com/content_author/drug-target-review/" rel="tag">Drug Target Review</a></p> <p class="listOnly">By studying organoids derived from adult stem cells, researchers made a discovery that could improve the development of personalised therapeutics.</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/news/153176/damaged-small-intestine-repaired-with-hpsc-derived-organoids/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="500" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="intestine" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-200x134.jpg 200w" data-sizes="(max-width: 750px) 100vw, 750px" /><noscript><img width="750" height="500" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="intestine" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-200x134.jpg 200w" sizes="(max-width: 750px) 100vw, 750px" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/news/153176/damaged-small-intestine-repaired-with-hpsc-derived-organoids/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="2560" height="1145" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-scaled.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="intestine" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-375x168.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-750x336.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-768x344.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-1536x687.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-2048x916.jpg 2048w" data-sizes="(max-width: 2560px) 100vw, 2560px" /><noscript><img width="2560" height="1145" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-scaled.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="intestine" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-375x168.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-750x336.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-768x344.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-1536x687.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2477011431-2048x916.jpg 2048w" sizes="(max-width: 2560px) 100vw, 2560px" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/news/">news</a></span> <h3><a href="https://www.drugtargetreview.com/news/153176/damaged-small-intestine-repaired-with-hpsc-derived-organoids/">Damaged small intestine repaired with hPSC-derived organoids</a></h3> <p class="meta">17 September 2024 | By <a href="https://www.drugtargetreview.com/content_author/drug-target-review/" rel="tag">Drug Target Review</a></p> <p class="listOnly">Cincinnati Children’s have repaired damaged intestines in a rodent model, moving research efforts closer to clinical trials.</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/news/152284/new-pathway-to-transition-neural-stem-cells-into-a-proliferative-state/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="500" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="astrocyte" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-200x134.jpg 200w" data-sizes="(max-width: 750px) 100vw, 750px" /><noscript><img width="750" height="500" src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="astrocyte" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-200x134.jpg 200w" sizes="(max-width: 750px) 100vw, 750px" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/news/152284/new-pathway-to-transition-neural-stem-cells-into-a-proliferative-state/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" 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class="attachment-article-standard size-article-standard wp-post-image" alt="astrocyte" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-scaled.jpg 2560w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-375x205.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-750x409.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-768x419.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-1536x838.jpg 1536w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_2185677641-2048x1117.jpg 2048w" sizes="(max-width: 2560px) 100vw, 2560px" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/news/">news</a></span> <h3><a href="https://www.drugtargetreview.com/news/152284/new-pathway-to-transition-neural-stem-cells-into-a-proliferative-state/">New pathway to 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src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="720" height="801" data-src="https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="iPSC-derived cardiomyocytes" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes.jpg 720w, https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes-225x250.jpg 225w, https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes-449x500.jpg 449w" data-sizes="(max-width: 720px) 100vw, 720px" /><noscript><img width="720" height="801" src="https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes.jpg" class="attachment-article-standard size-article-standard wp-post-image" alt="iPSC-derived cardiomyocytes" decoding="async" srcset="https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes.jpg 720w, https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes-225x250.jpg 225w, https://www.drugtargetreview.com/wp-content/uploads/iPS-derived-Cardiomyocytes-449x500.jpg 449w" sizes="(max-width: 720px) 100vw, 720px" /></noscript></a></div> <div class="articleExcerpt">  <span> <a href="https://www.drugtargetreview.com/news/">news</a></span> <h3><a href="https://www.drugtargetreview.com/news/151799/new-agreement-to-progress-cardiovascular-disease-research/">New agreement to progress cardiovascular disease research</a></h3> <p class="meta">26 July 2024 | By <a href="https://www.drugtargetreview.com/content_author/drug-target-review/" rel="tag">Drug Target Review</a></p> <p class="listOnly">The agreement between Cartherics, The University of Sydney and The University of Queensland will further stem cell-derived heart muscle therapy for heart failure.</p> </div></article> 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the TGF-β signalling pathway produced effective antitumour activity against hepatocellular carcinoma.</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/news/151242/elucidating-the-loss-of-mobility-caused-by-lgmd2b/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="750" height="500" data-src="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_507914809-750x500.jpg" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="skeletal muscle" decoding="async" data-srcset="https://www.drugtargetreview.com/wp-content/uploads/shutterstock_507914809-750x500.jpg 750w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_507914809-375x250.jpg 375w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_507914809-768x512.jpg 768w, https://www.drugtargetreview.com/wp-content/uploads/shutterstock_507914809-1536x1024.jpg 1536w, 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mobility.</p> </div></article> <article> <div class="articleImage listOnly"> <a href="https://www.drugtargetreview.com/podcasts/small-molecules-for-regenerative-medicine/"> <img data-lazyloaded="1" src="data:image/gif;base64,R0lGODdhAQABAPAAAMPDwwAAACwAAAAAAQABAAACAkQBADs=" width="300" height="250" data-src="https://www.drugtargetreview.com/wp-content/uploads/DTR-podcast-graphic.webp" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="Drug Target Review podcast" decoding="async" /><noscript><img width="300" height="250" src="https://www.drugtargetreview.com/wp-content/uploads/DTR-podcast-graphic.webp" class="attachment-large-rectangle size-large-rectangle wp-post-image" alt="Drug Target Review podcast" decoding="async" /></noscript></a></div> <div class="articleImage gridOnly"> <a href="https://www.drugtargetreview.com/podcasts/small-molecules-for-regenerative-medicine/"> <img data-lazyloaded="1" 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