Assay Genie on LinkedIn: Interested in cancer metabolism and the Warburg Effect? Check out this…

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Check out this great post from Miren!"> <meta name="twitter:description" content="Interested in cancer metabolism and the Warburg Effect? Check out this great post from Miren!"> <meta property="og:description" content="Interested in cancer metabolism and the Warburg Effect? Check out this great post from Miren!"> <meta property="og:title" content="Assay Genie on LinkedIn: Interested in cancer metabolism and the Warburg Effect? Check out this…"> <meta name="twitter:title" content="Assay Genie on LinkedIn: Interested in cancer metabolism and the Warburg Effect? Check out this…"> <title>Assay Genie on LinkedIn: Interested in cancer metabolism and the Warburg Effect? Check out this…</title> <meta name="twitter:card" content="summary_large_image"> <meta name="robots" content="noarchive, max-image-preview:large"> <meta property="lnkd:url" content="https://www.linkedin.com/feed/update/urn:li:activity:7168134240222576640"> <meta property="og:type" content="article"> <meta property="og:url" content="https://www.linkedin.com/posts/assaygenie-company_interested-in-cancer-metabolism-and-the-warburg-activity-7168134240222576640-Oa0D"> <meta property="og:image" content="https://media.licdn.com/dms/image/v2/D4E22AQEVDx-ZXjWIzg/feedshare-shrink_2048_1536/feedshare-shrink_2048_1536/0/1708958651374?e=2147483647&v=beta&t=w3XF98GrRACxGdxmsetmTzXysTvgMTbhPwp9v5u7pUQ"> <meta name="twitter:image" content="https://media.licdn.com/dms/image/v2/D4E22AQEVDx-ZXjWIzg/feedshare-shrink_2048_1536/feedshare-shrink_2048_1536/0/1708958651374?e=2147483647&v=beta&t=w3XF98GrRACxGdxmsetmTzXysTvgMTbhPwp9v5u7pUQ"> <meta name="twitter:site" content="@linkedin"> <meta property="twitter:url" content="https://www.linkedin.com/posts/assaygenie-company_interested-in-cancer-metabolism-and-the-warburg-activity-7168134240222576640-Oa0D"> <meta name="clientSideIngraphs" content="1" data-gauge-metric-endpoint="/feedcontent-guest/api/ingraphs/gauge" data-counter-metric-endpoint="/feedcontent-guest/api/ingraphs/counter"> <link rel="stylesheet" href="https://static.licdn.com/aero-v1/sc/h/1j1vfapm9bmq1yb12tic339v9"> <script type="application/ld+json"> {"@context":"http://schema.org","@type":"SocialMediaPosting","@id":"https://www.linkedin.com/posts/assaygenie-company_interested-in-cancer-metabolism-and-the-warburg-activity-7168134240222576640-Oa0D","datePublished":"2024-02-27T06:46:20.331Z","image":{"url":"https://media.licdn.com/dms/image/v2/D4E22AQEVDx-ZXjWIzg/feedshare-shrink_2048_1536/feedshare-shrink_2048_1536/0/1708958651374?e=2147483647&v=beta&t=w3XF98GrRACxGdxmsetmTzXysTvgMTbhPwp9v5u7pUQ","@type":"ImageObject"},"articleBody":"🔬 Hi Community! 🔬\n\nEmbark on a journey through the intricate world of cancer metabolism with one of our blog posts!\n\nWe're excited to share insights into tumorigenesis, metabolic therapy, and exploring innovative therapeutic strategies.\n\nKey takeaways:\n\n🔍 Tumorigenesis & Cancer Metabolism: Unraveling the metabolic intricacies underlying cancer initiation and progression, from dysregulated glycolysis to altered mitochondrial function.\n\n🔬 The Warburg Effect: Understanding how cancer cells prioritize glycolysis for energy production, even in oxygen-rich environments.\n\n🎯 Metabolic Therapy: Harnessing the vulnerabilities of cancer metabolism for targeted interventions, with a focus on disrupting glycolysis and other key pathways.\n\n🌱 Metabolic Adaptations in the Tumor Microenvironment: Learning how the dynamic interplay between cancer cells and their surroundings shapes metabolic landscapes and influences treatment response.\n\nStay informed, stay inspired!\n\nRead more: [https://lnkd.in/ebz34pqy]\n\n#CancerResearch #MetabolicTherapy #WarburgEffect #Tumorigenesis #PersonalizedMedicine #AssayGenie","sharedContent":{"@type":"WebPage"},"author":{"name":"Assay Genie","image":{"url":"https://media.licdn.com/dms/image/v2/C4E0BAQG3gToPkUnjog/company-logo_100_100/company-logo_100_100/0/1630625153692/reagent_genie_logo?e=2147483647&v=beta&t=RbU5xVkGk175NH79dXcgnYLqkEtmTReqkv-tsKpgUjQ","@type":"ImageObject"},"url":"https://ie.linkedin.com/company/assaygenie-company","@type":"Organization","interactionStatistic":{"@type":"InteractionCounter","interactionType":"http://schema.org/FollowAction","userInteractionCount":0}},"hasPart":{"@type":"WebPageElement","isAccessibleForFree":false,"cssSelector":".details"}} </script>  </head> <body dir="ltr">  <form class="google-auth" action="https://www.linkedin.com/uas/login-submit" method="post"> <input name="loginCsrfParam" value="afa4ba86-da47-4258-8565-a47353f5c041" type="hidden">  <input name="trk" 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class="flex-none"> 8mo  </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/671xosfpvk4c0kqtyl87hashi"></icon> </button> <ul class="collapsible-dropdown__list hidden container-raised absolute w-auto overflow-y-auto flex-col items-stretch z-1 bottom-auto top-[100%]" role="menu" tabindex="-1"> <li class="ellipsis-menu__item border-t-1 border-solid border-color-border-low-emphasis first-of-type:border-none flex"> <a 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Check out this great post from Miren!</p>  </div> <article aria-label="Reshared post" class="relative pt-1.5 px-2 pb-1 mb-1 babybear:pt-0.5 babybear:pb-0 babybear:mb-0 container-lined bg-color-background-container feed-reshare-content" data-test-id="feed-reshare-content" data-attributed-urn="urn:li:share:7167892113123184640" data-activity-urn="urn:li:activity:7167892113844613120" tabindex="0"> <div class="flex items-center font-sans" data-test-id="feed-reshare-content__entity-lockup"> <a href="https://ie.linkedin.com/in/mirenrde?trk=public_post_reshare_feed-actor-image" target="_self" class="relative" data-tracking-control-name="public_post_reshare_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/D4E03AQFfaeF02hsAHQ/profile-displayphoto-shrink_400_400/profile-displayphoto-shrink_400_400/0/1720435350900?e=2147483647&v=beta&t=LBywyc7pi-1mw1RaXOqdH3VIzCKQMmCQN_-p_0il63c" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="View profile for Miren Ruiz de Eguilaz, PhD., graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://ie.linkedin.com/in/mirenrde?trk=public_post_reshare_feed-actor-name" target="_self" data-tracking-control-name="public_post_reshare_feed-actor-name" aria-label="View profile for Miren Ruiz de Eguilaz, PhD." data-tracking-will-navigate> Miren Ruiz de Eguilaz, PhD. </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  Scientific Sales Specialist & Account Manager </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 9mo  </time>  </span> </div>  </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="feed-reshare-content__commentary">🔬 Hi Community! 🔬 Embark on a journey through the intricate world of cancer metabolism with one of our blog posts! We're excited to share insights into tumorigenesis, metabolic therapy, and exploring innovative therapeutic strategies. Key takeaways: 🔍 Tumorigenesis & Cancer Metabolism: Unraveling the metabolic intricacies underlying cancer initiation and progression, from dysregulated glycolysis to altered mitochondrial function. 🔬 The Warburg Effect: Understanding how cancer cells prioritize glycolysis for energy production, even in oxygen-rich environments. 🎯 Metabolic Therapy: Harnessing the vulnerabilities of cancer metabolism for targeted interventions, with a focus on disrupting glycolysis and other key pathways. 🌱 Metabolic Adaptations in the Tumor Microenvironment: Learning how the dynamic interplay between cancer cells and their surroundings shapes metabolic landscapes and influences treatment response. Stay informed, stay inspired! Read more: [<a class="link" href="https://lnkd.in/ebz34pqy?trk=public_post_reshare-text" target="_self" rel="nofollow" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>https://lnkd.in/ebz34pqy</a>] <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerresearch&trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#CancerResearch</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmetabolictherapy&trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#MetabolicTherapy</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fwarburgeffect&trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#WarburgEffect</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ftumorigenesis&trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#Tumorigenesis</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fpersonalizedmedicine&trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#PersonalizedMedicine</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fassaygenie&trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#AssayGenie</a></p> 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aria-label="Post by Miren Ruiz de Eguilaz, PhD." class="absolute left-0 top-0 h-full w-full z-1 !border-0" data-tracking-control-name="link-overlay-public_post" href="https://www.linkedin.com/posts/mirenrde_cancerresearch-metabolictherapy-warburgeffect-activity-7167892113844613120-8Fhl" target="_self"></a> <article class="relative pt-1.5 px-2 pb-0 bg-color-background-container container-lined main-feed-activity-card related-posts__crosslink" data-activity-urn="urn:li:activity:7167892113844613120" data-featured-activity-urn="urn:li:activity:7167892113844613120" data-attributed-urn="urn:li:share:7167892113123184640">   <div class="flex items-center font-sans mb-1" data-test-id="main-feed-activity-card__entity-lockup"> <a href="https://ie.linkedin.com/in/mirenrde?trk=public_post_feed-actor-image" class="relative" data-tracking-control-name="public_post_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/D4E03AQFfaeF02hsAHQ/profile-displayphoto-shrink_400_400/profile-displayphoto-shrink_400_400/0/1720435350900?e=2147483647&v=beta&t=LBywyc7pi-1mw1RaXOqdH3VIzCKQMmCQN_-p_0il63c" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="View profile for Miren Ruiz de Eguilaz, PhD., graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://ie.linkedin.com/in/mirenrde?trk=public_post_feed-actor-name" data-tracking-control-name="public_post_feed-actor-name" aria-label="View profile for Miren Ruiz de Eguilaz, PhD." data-tracking-will-navigate> Miren Ruiz de Eguilaz, PhD. </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  Scientific Sales Specialist & Account Manager </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 9mo  </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/671xosfpvk4c0kqtyl87hashi"></icon> </button> <ul class="collapsible-dropdown__list hidden container-raised absolute w-auto overflow-y-auto flex-col items-stretch z-1 bottom-auto top-[100%]" role="menu" tabindex="-1"> <li class="ellipsis-menu__item border-t-1 border-solid 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We're excited to share insights into tumorigenesis, metabolic therapy, and exploring innovative therapeutic strategies. Key takeaways: 🔍 Tumorigenesis & Cancer Metabolism: Unraveling the metabolic intricacies underlying cancer initiation and progression, from dysregulated glycolysis to altered mitochondrial function. 🔬 The Warburg Effect: Understanding how cancer cells prioritize glycolysis for energy production, even in oxygen-rich environments. 🎯 Metabolic Therapy: Harnessing the vulnerabilities of cancer metabolism for targeted interventions, with a focus on disrupting glycolysis and other key pathways. 🌱 Metabolic Adaptations in the Tumor Microenvironment: Learning how the dynamic interplay between cancer cells and their surroundings shapes metabolic landscapes and influences treatment response. Stay informed, stay inspired! Read more: [<a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2Febz34pqy&urlhash=Renf&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/ebz34pqy</a>] <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerresearch&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CancerResearch</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmetabolictherapy&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#MetabolicTherapy</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fwarburgeffect&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#WarburgEffect</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Ftumorigenesis&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#Tumorigenesis</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fpersonalizedmedicine&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#PersonalizedMedicine</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fassaygenie&trk=public_post-text" 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data-test-id="main-feed-activity-card__commentary">I'm not sure how I got this far before highlighting CD8, but here we are. 🌰 CD8 in a nutshell: -Arguably, one of the most important biomarkers in the research, clinical, and translational medicine spaces. -CD8 defines cytotoxic effector cells, subsets of natural killer and regulatory cells, and is a co-receptor for MHC-I molecules. -Cytotoxic T cells expressing this marker are the [most powerful] effectors in the anticancer immune response and are integral to the success of cancer immunotherapies. -Acts as a prognostic marker for numerous diseases/cancers including, but not limited to, sepsis, TNBC, renal cancer, and lung SCC. 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" dir="ltr" data-test-id="main-feed-activity-card__commentary">Is <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdurvalumab&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#Durvalumab</a> a breakthrough treatment for gallbladder cancer? Gallbladder cancer (GBC) is one of the most prevalent among biliary tract duct cancers globally. It develops within the lining of the gallbladder. The majority of the patients are diagnosed at an advanced stage of the illness, leaving themselves with fewer therapeutic options and a grim prognosis. Thus, early detection of this cancer and cutting-edge treatment options are required to boost survival prospects. The results of ongoing clinical trials evaluating durvalumab and other immunotherapies are eagerly awaited to assess if checkpoint inhibitors can improve clinical outcomes for patients with advanced gallbladder cancer. In the future, precise predictive biomarkers will be necessary to help clinicians decide whether a patient will respond to checkpoint inhibitors. 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data-test-id="main-feed-activity-card__commentary">On World Lung Cancer Day, let’s acknowledge one of the most significant advancements in the battle against lung cancer - the identification and development of therapies targeting specific driver mutations. A recent paper from Lancet provides a concise overview of current and emerging biomarkers, emphasizing the growing importance of next-generation sequencing in optimizing treatment strategies. (Source: Lancet Regional Health - Europe 2024;38: 100839) <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fworldlungcancerday&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#worldlungcancerday</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Flungcancer&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#lungcancer</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fbiomarkers&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#biomarkers</a> <a class="link" 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href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerimmunotherapy&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#cancerimmunotherapy</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fimmunology&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#immunology</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fimmunostaining&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#immunostaining</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmultiplex&trk=public_post-text" target="_self" 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data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="View profile for Danielle Fails, MSc, graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://www.linkedin.com/in/danielle-fails?trk=public_post_reshare_feed-actor-name" target="_self" data-tracking-control-name="public_post_reshare_feed-actor-name" aria-label="View profile for Danielle Fails, MSc" data-tracking-will-navigate> Danielle Fails, MSc </a>  </div>  <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 8mo  </time>  </span> </div>  </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="feed-reshare-content__commentary">I'm not sure how I got this far before highlighting CD8, but here we are. 🌰 CD8 in a nutshell: -Arguably, one of the most important biomarkers in the research, clinical, and translational medicine spaces. -CD8 defines cytotoxic effector cells, subsets of natural killer and regulatory cells, and is a co-receptor for MHC-I molecules. -Cytotoxic T cells expressing this marker are the [most powerful] effectors in the anticancer immune response and are integral to the success of cancer immunotherapies. -Acts as a prognostic marker for numerous diseases/cancers including, but not limited to, sepsis, TNBC, renal cancer, and lung SCC. 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href="https://www.linkedin.com/posts/stefanledinger_science-metabolism-immunotherapy-activity-7156231981733720064-olei" target="_self"></a> <article class="relative pt-1.5 px-2 pb-0 bg-color-background-container container-lined main-feed-activity-card related-posts__crosslink" data-activity-urn="urn:li:activity:7156231981733720064" data-featured-activity-urn="urn:li:activity:7156231981733720064" data-attributed-urn="urn:li:share:7156231980563456000">   <div class="flex items-center font-sans mb-1" data-test-id="main-feed-activity-card__entity-lockup"> <a href="https://at.linkedin.com/in/stefanledinger?trk=public_post_feed-actor-image" class="relative" data-tracking-control-name="public_post_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative rounded-[50%] w-6 h-6 bg-color-entity-ghost-background" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="View profile for Stefan Ledinger, graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://at.linkedin.com/in/stefanledinger?trk=public_post_feed-actor-name" data-tracking-control-name="public_post_feed-actor-name" aria-label="View profile for Stefan Ledinger" data-tracking-will-navigate> Stefan Ledinger </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  Creating Scientific Success Stories with Metabolomics and Multiomics </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 10mo  </time>  </span> </div>  </div> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative 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This novel review must be the ideal addition to yesterday's post. It is broader in terms of the metabolic pathways that it looks at, while it is narrower in terms of the cell types discussed, focussing on the role of macrophages. <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2Fdbv9EnWg&urlhash=W8xp&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/dbv9EnWg</a>. Interestingly, besides having a very balanced discussion about opportunities and challenges, the authors discuss the prerequisites for metabolic target discovery and the eventual possibility of metabolic phenotyping as a tool for precision medicine in this setting. An interesting read penned by <a class="link" href="https://www.linkedin.com/in/corey-dussold-b72a5b296?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Corey Dussold</a>, <a class="link" href="https://www.linkedin.com/in/kaylee-zilinger-1757301b4?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Kaylee Zilinger</a>, <a class="link" href="https://www.linkedin.com/in/jillyn-turunen-7bb0a9177?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Jillyn Turunen</a>, <a class="link" href="https://www.linkedin.com/in/amy-heimberger-830b3a213?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Amy Heimberger</a>, and <a class="link" href="https://www.linkedin.com/in/jason-miska-02b15396?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Jason Miska</a> from <a class="link" href="https://www.linkedin.com/school/northwestern-university-feinberg-school-of-medicine/?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Northwestern University - The Feinberg School of Medicine</a>. Full publication: Modulation of macrophage metabolism as an emerging immunotherapy strategy for cancer. J Clin Invest. 2024;134(2):e175445. <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FdiXbDnFW&urlhash=0tsb&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/diXbDnFW</a>. Paper and picture (Figure 1) freely available under a Creative Commons license: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FdQ3ekaXg&urlhash=7qhn&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/dQ3ekaXg</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fscience&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#science</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmetabolism&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#metabolism</a> <a class="link" 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This research reveals the impact of evolutionary differences on therapeutic efficacy. 🌟 <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FfBPw9Ug&urlhash=hKIl&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/fBPw9Ug</a> 🚀HLAtyping Panel v2.0 represents the latest database (Version 3.50), targeting 11 HLA genes. The probe encompasses the entire genome sequence (UTR, Exon, Intron) of all alleles, ensuring comprehensive coverage for all types.🚀 🎯 Our state-of-the-art typing technology achieves precise classification down to the fourth field level, encompassing HLA-A, B, C (class I), and HLA-DPA1, DPB1, DQA1, DQB1, DRB1/3/4/5 (class II). This innovation paves the way for tailored treatments and improved patient outcomes. 🎯 Dive into the product: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FgGZdd2sy&urlhash=uN_U&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/gGZdd2sy</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerresearch&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CancerResearch</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fimmunotherapy&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#Immunotherapy</a> <a class="link" 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highlight the Berriel Diaz Lab at <a class="link" href="https://de.linkedin.com/company/helmholtzmunich?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Helmholtz Munich</a>, Germany. Led by Dr. <a class="link" href="https://de.linkedin.com/in/mauricio-berriel-diaz-4b41229?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Mauricio Berriel Diaz</a>, this lab delves into the complexities of metabolism and cancer. 🌟 🔍 Key highlights: Metabolic Dysfunction and Cancer: Investigating how obesity, insulin resistance, and type 2 diabetes increase cancer risk in the gastrointestinal tract, liver, kidney, and breast. 🧬🔍 Cancer Cachexia: Studying how lung, colorectal, and pancreatic cancers cause severe muscle and fat loss, impacting treatment. 🧠🔬 In-Vivo and In-Vitro Models: Using these models to explore metabolic dysfunction and cancer interactions. 🔬💡 Molecular Mechanisms: Uncovering mechanisms behind these interactions to develop better treatments. 🧪📊 For more insights into their pioneering work visit: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FgNMTsdhe&urlhash=n1Tg&trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/gNMTsdhe</a> Credits: Poster - <a class="link" href="https://in.linkedin.com/in/smrutimayeeprusty?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Smrutimayee Prusty</a> Content - <a class="link" href="https://in.linkedin.com/in/abhilasha-sonawane-30ab12235?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Abhilasha Sonawane</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Flabshowcase&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#LabShowcase</a> <a class="link" 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Assay Genie on LinkedIn: Interested in cancer metabolism and the Warburg Effect? Check out this…