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Unmet clinical needs drive patient interest in clinical trial participation in Major Depressive Disorder - IQVIA

<!DOCTYPE html> <!--[if IE 9]><html lang="en" class="ie9 no-js"><![endif]--> <!--[if !IE]><!--> <html lang="en"> <!--<![endif]--> <head> <meta charset="utf-8" /> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta http-equiv="Content-type" content="text/html; charset=utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1, maximum-scale=1, user-scalable=no"> <meta name="msapplication-TileImage" content="/Content/Shotgun/img/favicon/ms-icon-144x144.png?v=4" /> <link rel="apple-touch-icon-precomposed" href="/Content/Shotgun/img/favicon/apple-icon-precomposed.png?v=4" /> <link rel="icon" href="/Content/Shotgun/img/favicon/favicon.ico?v=4" /><style> .coveo-card-layout a::after { display: none !important; } </style><!-- Google Tag Manager --> <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-P97VBCW');</script> <!-- End Google Tag Manager --><meta name="google-site-verification" content="EyIQB7GdOQ83t4xrzV8zE-Gs_mjfgD-VO1TZkSkbKSc" /><!-- No Custom Fonts --> <!-- BEGIN NOINDEX --> <title>Unmet clinical needs drive patient interest in clinical trial participation in Major Depressive Disorder - IQVIA</title> <!-- END NOINDEX --> <link rel="canonical" href="https://www.iqvia.com/blogs/2024/10/unmet-clinical-needs-drive-patient-interest" /> <meta name="keywords" content="Major Depressive Disorder, MDD, MQ Mental Health Research, Unmet clinical needs, Patient interest, Clinical trial participation, Mental health, Depression, Anxiety, antidepressants, COVID-19 pandemic, Pharmaceutical treatment, Psychotherapy, Supportive complementary treatments, Patient support programs, living with MDD, Mental health diagnosis, MMD treatment, Clinical studies, Real world evidence (RWE) studies, Patient compliance and adherence, patient support systems, patient organizations" /> <meta name="description" content="Major Depressive Disorder (MDD) patients face significant unmet clinical needs, driving interest in clinical trials. Challenges include finding effective pharmaceutical treatments, accessing psychotherapy, and managing side effects. Support programs focusing on self-efficacy and reducing self-stigma are essential for improving patient outcomes." /> <meta name="iq:related_solutions" content="Real World Evidence, Patient Engagement and Support" /> <meta name="iq:market_segment" content="Patient advocacy group,Traditional or branded Pharma,Emerging Biopharma (EBP),Generics,Payers,Government" /> <meta name="iq:region" content="Global" /> <meta name="iq:market_product" content="IQVIA" /> <meta name="iq:business_area" content="Real World,Analytics Solutions,Consulting,Contract Sales &amp; Medical Solutions" /> <meta name="iq:regional_business_unit" content="Global" /> <meta name="iq:persona" content="Richard- Brand Leader,Kelly- Brand Director,Paul- Market Access,Nick- Therapeutic Franchise Owner,Gilbert and Rachel- Clinical Operations,Rachel- Clinical Operations - Small/Mid,Diana- Medical Affairs,Edward- HEOR" /> <meta name="iq:thought_leadership" content="" /> <meta property="og:title" content="Unmet clinical needs drive patient interest in clinical trial participation in Major Depressive Disorder" /> <meta property="twitter:title" content="Unmet clinical needs drive patient interest in clinical trial participation in Major Depressive Disorder" /> <meta property="og:image" content="https://www.iqvia.com/-/media/iqvia/images/modules/brandworld/2698_patient-talking-to-doctor-in-medical-clinic.jpg" /> <meta property="twitter:image" content="https://www.iqvia.com/-/media/iqvia/images/modules/brandworld/2698_patient-talking-to-doctor-in-medical-clinic.jpg" /> <meta property="og:description" content="&lt;h5&gt;&lt;span&gt;&lt;strong&gt;Rising burden of disease&lt;/strong&gt;&lt;/span&gt;&lt;/h5&gt; &lt;p&gt;&lt;span&gt;Depressive disorders are among the most prevalent conditions globally and the associated burden of disease is growing. For many people these are life-altering, chronic conditions which not only affect every aspect of their daily lives but can also have considerable impact on their loved ones.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;The WHO estimates the global impact of depressive disorders at 57m Disability-adjusted life years (DALYs) in 2021, putting them in 13&lt;sup style=&quot;line-height:10px;font-size:12px;&quot;&gt;th&lt;/sup&gt; place, up from 37m DALYs and rank 19 in 2000.&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;1&lt;/sup&gt; In part at least this increase is associated with the COVID-19 pandemic - according to the WHO, the number of people suffering from depression and anxiety went up by 25% in the first year of the pandemic alone&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;2&lt;/sup&gt;.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;Global spending on mental health medication is also expected to increase in the next years. The figure currently stands at 81bn USD, with a projected 9-12% CAGR until 2028, exceeding the projected total market growth of 5-8%&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;3&lt;/sup&gt;. There is also considerable potential for future innovative therapies: although trial starts in 2023 were below the pre-pandemic level, there are currently nearly 250 ongoing trials covering a wide range of MoAs&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;4&lt;/sup&gt;.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;However, pharmaceutical treatment is only part of the picture in managing Major Depressive Disorder (MDD). People affected by MDD also benefit from psychotherapy and supportive complementary treatments like meditation or sports to improve overall well-being. Support programmes for patients with a focus on self-efficacy and reducing self-stigma can also be helpful. Overall, though, there is still considerable unmet need.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;IQVIA partnered with patient organisation MQ Mental Health Research to conduct a survey of people living with MDD to discover which difficulties they encounter in the course of diagnosis, treatment, and adjusting to living with the disease and where they could benefit from additional support. The survey consisted of in-depth interviews with six participants with moderately severe to severe MDD based in the UK, the US, and Spain.&lt;/span&gt;&lt;/p&gt; &lt;br /&gt; &lt;p&gt;&lt;span&gt;The information provided in these interviews reflects both the pervasive impact of MDD and the considerable unmet needs in treating and managing it.&lt;/span&gt;&lt;/p&gt; &lt;br /&gt; &lt;h5&gt;&lt;span&gt;&lt;strong&gt;Unmet clinical need drives motivation to participate in clinical trials&lt;/strong&gt;&lt;/span&gt;&lt;/h5&gt; &lt;p&gt;&lt;span&gt;With regard to pharmaceutical treatment, patients report that finding a helpful pharmaceutical regime is challenging since it often involves a combination of drugs, for instance anti-depressants combined with anti-anxiety medication. They are also often unhappy with the side effects of antidepressants which they describe as &amp;ldquo;numbing&amp;rdquo; or making them feel &amp;ldquo;like a zombie&amp;rdquo; but do not restore the lost feeling of well-being or the ability to function in day-to-day life. In addition, the medication is not effective immediately but takes some time to build up which can make it difficult to disentangle which changes in a patient&amp;rsquo;s condition are the result of medication or of other interventions.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;Psychotherapy is perceived as helpful, but people often experience barriers to access &amp;ndash; sometimes other doctors do not want to refer the patient, there may be no therapists available in a reasonable timeframe, or psychotherapy is not covered by the patient&amp;rsquo;s insurance. It can also take time to build up trust and sometimes several tries to find a therapist with whom the patient feels comfortable.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;The lack of efficacious pharmaceuticals experienced by the patients IQVIA spoke to drives a willingness to participate in clinical studies provided certain conditions are met. For these patients, the prospect of getting early access to new therapies which might improve their overall condition is a key reason to consider clinical trials. It is however imperative that potential participants feel well informed and well taken care of. Information needs to centre around understanding the medication being tested, what possible side effects there are and the potential outcomes. Information about the logistics of the trial and what is being expected of the participants is also essential. It is important that this information is delivered by the participants&amp;rsquo; own HCP or by clinical trial staff in a sensitive, empathic manner, with enough time taken to answer questions. Booklets for follow-up are also valuable.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;In designing clinical trials, the severe impact of MDD on people&amp;rsquo;s executive function must be taken into account. Issues such as fatigue, brain fog, lack of motivation and organisation, social anxiety and similar topics are very commonly reported. In order to ensure participants&amp;rsquo; adherence and compliance, practical and motivational support must be ensured to overcome these barriers.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;The motivation for participating in real world studies and for sharing data is somewhat lower than for participating in clinical trials. This is largely due to a lack of understanding of the purpose and value of RWE studies and a reluctance to share confidential and often very personal insights into their emotional and mental state with people they do not know and have no opportunity to establish a trust-based relationship with. The potential benefit of gaining early access to new therapies is also lacking. This reluctance could potentially be overcome by building awareness about the benefit of RWE studies and cultivating relationships with patient communities.&lt;/span&gt;&lt;/p&gt; &lt;br /&gt; &lt;h5&gt;&lt;span&gt;&lt;strong&gt;An opening for pharma&lt;/strong&gt;&lt;/span&gt;&lt;/h5&gt; &lt;p&gt;&lt;span&gt;There is also an opportunity for pharma to step into the gap where patient support is concerned &amp;ndash; interview partners report that they rely primarily on their families and people close to them for practical and psychological support. Further sources are social media and patient support groups where experiences and information can be shared. Pharma, on the other hand, is not perceived as being in the business of supporting patients &amp;ndash; &amp;ldquo;that&amp;rsquo;s not what they do, is it?&amp;rdquo;&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;Given the unmet need reported in terms of information and guidance on managing life with MDD and also the challenges outlined above in informing and motivating patients to participate in clinical trials and share data for RWE studies, there is some potential here for pharma to tap provided they step carefully and focus on building relationships with the patient community based on respect and trust. Building and nurturing such support systems could benefit patients by helping them better understand and manage their condition, and pharma by improving patient compliance and adherence through better expectation management as well as participation in clinical trials and RWE studies.&lt;/span&gt;&lt;/p&gt; &lt;div&gt;&lt;br clear=&quot;all&quot; /&gt; &lt;hr align=&quot;left&quot; size=&quot;1&quot; width=&quot;33%&quot; /&gt; &lt;div id=&quot;edn1&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;span&gt; &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys&quot; target=&quot;_blank&quot;&gt;https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys&lt;/a&gt; , accessed Sep 18, 2024&lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div id=&quot;edn2&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;span&gt; &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.who.int/publications/i/item/9789240050860&quot; target=&quot;_blank&quot;&gt;World mental health report: Transforming mental health for all - executive summary (who.int)&lt;/a&gt;&lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div id=&quot;edn3&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;span&gt; Source: IQVIA Institute for Human Data Science. Global Use of Medicines: Outlook to 2028, January 2024. &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/the-global-use-of-medicines-2024-outlook-to-2028&quot; target=&quot;_blank&quot;&gt;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/the-global-use-of-medicines-2024-outlook-to-2028&lt;/a&gt; &lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div id=&quot;edn4&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;span&gt; Source: IQVIA Institute for Human Data Science. Global Trends in R&amp;amp;D 2024: Activity, Productivity, and Enablers. February 2024. &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2024-activity-productivity-and-enablers&quot; target=&quot;_blank&quot;&gt;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2024-activity-productivity-and-enablers&lt;/a&gt; &lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;/div&gt;" /> <meta property="twitter:description" content="&lt;h5&gt;&lt;span&gt;&lt;strong&gt;Rising burden of disease&lt;/strong&gt;&lt;/span&gt;&lt;/h5&gt; &lt;p&gt;&lt;span&gt;Depressive disorders are among the most prevalent conditions globally and the associated burden of disease is growing. For many people these are life-altering, chronic conditions which not only affect every aspect of their daily lives but can also have considerable impact on their loved ones.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;The WHO estimates the global impact of depressive disorders at 57m Disability-adjusted life years (DALYs) in 2021, putting them in 13&lt;sup style=&quot;line-height:10px;font-size:12px;&quot;&gt;th&lt;/sup&gt; place, up from 37m DALYs and rank 19 in 2000.&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;1&lt;/sup&gt; In part at least this increase is associated with the COVID-19 pandemic - according to the WHO, the number of people suffering from depression and anxiety went up by 25% in the first year of the pandemic alone&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;2&lt;/sup&gt;.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;Global spending on mental health medication is also expected to increase in the next years. The figure currently stands at 81bn USD, with a projected 9-12% CAGR until 2028, exceeding the projected total market growth of 5-8%&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;3&lt;/sup&gt;. There is also considerable potential for future innovative therapies: although trial starts in 2023 were below the pre-pandemic level, there are currently nearly 250 ongoing trials covering a wide range of MoAs&lt;sup style=&quot;font-size:12px;line-height:10px;&quot;&gt;4&lt;/sup&gt;.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;However, pharmaceutical treatment is only part of the picture in managing Major Depressive Disorder (MDD). People affected by MDD also benefit from psychotherapy and supportive complementary treatments like meditation or sports to improve overall well-being. Support programmes for patients with a focus on self-efficacy and reducing self-stigma can also be helpful. Overall, though, there is still considerable unmet need.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;IQVIA partnered with patient organisation MQ Mental Health Research to conduct a survey of people living with MDD to discover which difficulties they encounter in the course of diagnosis, treatment, and adjusting to living with the disease and where they could benefit from additional support. The survey consisted of in-depth interviews with six participants with moderately severe to severe MDD based in the UK, the US, and Spain.&lt;/span&gt;&lt;/p&gt; &lt;br /&gt; &lt;p&gt;&lt;span&gt;The information provided in these interviews reflects both the pervasive impact of MDD and the considerable unmet needs in treating and managing it.&lt;/span&gt;&lt;/p&gt; &lt;br /&gt; &lt;h5&gt;&lt;span&gt;&lt;strong&gt;Unmet clinical need drives motivation to participate in clinical trials&lt;/strong&gt;&lt;/span&gt;&lt;/h5&gt; &lt;p&gt;&lt;span&gt;With regard to pharmaceutical treatment, patients report that finding a helpful pharmaceutical regime is challenging since it often involves a combination of drugs, for instance anti-depressants combined with anti-anxiety medication. They are also often unhappy with the side effects of antidepressants which they describe as &amp;ldquo;numbing&amp;rdquo; or making them feel &amp;ldquo;like a zombie&amp;rdquo; but do not restore the lost feeling of well-being or the ability to function in day-to-day life. In addition, the medication is not effective immediately but takes some time to build up which can make it difficult to disentangle which changes in a patient&amp;rsquo;s condition are the result of medication or of other interventions.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;Psychotherapy is perceived as helpful, but people often experience barriers to access &amp;ndash; sometimes other doctors do not want to refer the patient, there may be no therapists available in a reasonable timeframe, or psychotherapy is not covered by the patient&amp;rsquo;s insurance. It can also take time to build up trust and sometimes several tries to find a therapist with whom the patient feels comfortable.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;The lack of efficacious pharmaceuticals experienced by the patients IQVIA spoke to drives a willingness to participate in clinical studies provided certain conditions are met. For these patients, the prospect of getting early access to new therapies which might improve their overall condition is a key reason to consider clinical trials. It is however imperative that potential participants feel well informed and well taken care of. Information needs to centre around understanding the medication being tested, what possible side effects there are and the potential outcomes. Information about the logistics of the trial and what is being expected of the participants is also essential. It is important that this information is delivered by the participants&amp;rsquo; own HCP or by clinical trial staff in a sensitive, empathic manner, with enough time taken to answer questions. Booklets for follow-up are also valuable.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;In designing clinical trials, the severe impact of MDD on people&amp;rsquo;s executive function must be taken into account. Issues such as fatigue, brain fog, lack of motivation and organisation, social anxiety and similar topics are very commonly reported. In order to ensure participants&amp;rsquo; adherence and compliance, practical and motivational support must be ensured to overcome these barriers.&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;The motivation for participating in real world studies and for sharing data is somewhat lower than for participating in clinical trials. This is largely due to a lack of understanding of the purpose and value of RWE studies and a reluctance to share confidential and often very personal insights into their emotional and mental state with people they do not know and have no opportunity to establish a trust-based relationship with. The potential benefit of gaining early access to new therapies is also lacking. This reluctance could potentially be overcome by building awareness about the benefit of RWE studies and cultivating relationships with patient communities.&lt;/span&gt;&lt;/p&gt; &lt;br /&gt; &lt;h5&gt;&lt;span&gt;&lt;strong&gt;An opening for pharma&lt;/strong&gt;&lt;/span&gt;&lt;/h5&gt; &lt;p&gt;&lt;span&gt;There is also an opportunity for pharma to step into the gap where patient support is concerned &amp;ndash; interview partners report that they rely primarily on their families and people close to them for practical and psychological support. Further sources are social media and patient support groups where experiences and information can be shared. Pharma, on the other hand, is not perceived as being in the business of supporting patients &amp;ndash; &amp;ldquo;that&amp;rsquo;s not what they do, is it?&amp;rdquo;&lt;/span&gt;&lt;/p&gt; &lt;p&gt;&lt;span&gt;Given the unmet need reported in terms of information and guidance on managing life with MDD and also the challenges outlined above in informing and motivating patients to participate in clinical trials and share data for RWE studies, there is some potential here for pharma to tap provided they step carefully and focus on building relationships with the patient community based on respect and trust. Building and nurturing such support systems could benefit patients by helping them better understand and manage their condition, and pharma by improving patient compliance and adherence through better expectation management as well as participation in clinical trials and RWE studies.&lt;/span&gt;&lt;/p&gt; &lt;div&gt;&lt;br clear=&quot;all&quot; /&gt; &lt;hr align=&quot;left&quot; size=&quot;1&quot; width=&quot;33%&quot; /&gt; &lt;div id=&quot;edn1&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;span&gt; &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys&quot; target=&quot;_blank&quot;&gt;https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys&lt;/a&gt; , accessed Sep 18, 2024&lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div id=&quot;edn2&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;span&gt; &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.who.int/publications/i/item/9789240050860&quot; target=&quot;_blank&quot;&gt;World mental health report: Transforming mental health for all - executive summary (who.int)&lt;/a&gt;&lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div id=&quot;edn3&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;span&gt; Source: IQVIA Institute for Human Data Science. Global Use of Medicines: Outlook to 2028, January 2024. &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/the-global-use-of-medicines-2024-outlook-to-2028&quot; target=&quot;_blank&quot;&gt;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/the-global-use-of-medicines-2024-outlook-to-2028&lt;/a&gt; &lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div id=&quot;edn4&quot;&gt; &lt;p style=&quot;font-size:12px;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;span&gt; Source: IQVIA Institute for Human Data Science. Global Trends in R&amp;amp;D 2024: Activity, Productivity, and Enablers. February 2024. &lt;a rel=&quot;noopener noreferrer&quot; href=&quot;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2024-activity-productivity-and-enablers&quot; target=&quot;_blank&quot;&gt;https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2024-activity-productivity-and-enablers&lt;/a&gt; &lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;/div&gt;" /> <meta property="og:url" content="https://www.iqvia.com/blogs/2024/10/unmet-clinical-needs-drive-patient-interest" /> <meta property="twitter:site" content="https://www.iqvia.com/blogs/2024/10/unmet-clinical-needs-drive-patient-interest" /> <link href="/Content/Shotgun/css/coveo?v=5f2TXK9t8FlC_0aw4cAoVYcmCiwv63sB9xo1gz4KnGg1" rel="stylesheet"/> <link href="/Content/Shotgun/css/main?v=R2OdW1uvbPjT4Hyp9vUX2IxrR3HCzyWr38h5Y4R6OTE1" rel="stylesheet"/> <link rel="stylesheet" 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<li><a href="https://www.iqvia.com/nl-nl/locations/netherlands">Nederland</a></li> <li><a href="https://www.iqvia.com/locations/nordics">Nordics</a></li> <li><a href="https://www.iqvia.com/pl-pl/locations/poland">Poland</a></li> <li><a href="https://www.iqvia.com/pt-pt/locations/portugal">Portugal</a></li> <li><a href="https://www.iqvia.com/locations/romania">Romania</a></li> <li><a href="https://www.iqvia.com/locations/russia">Russia</a></li> <li><a href="https://www.iqvia.com/locations/slovakia">Slovakia</a></li> <li><a href="https://www.iqvia.com/locations/switzerland">Switzerland</a></li> <li><a href="https://www.iqvia.com/locations/turkey">Turkey</a></li> <li><a href="https://www.iqvia.com/locations/ukraine">Ukraine</a></li> <li><a href="https://www.iqvia.com/locations/united-kingdom">United Kingdom</a></li> </ul> </div> <div class="regional-promoted mobile"> <div class="w-65"> <div class="w-33"> <div class="card-wrapper"> <div class="card"> <img 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</div> </div> </li> <li> <img src="/-/media/iqvia/mea.svg"> <div class="d-block"> <h3>Middle East &amp; Africa</h3> </div> <div class="sub-content"> <h6>Middle East &amp; Africa</h6> <ul class="sub-list" style="float:left"> <li><a href="https://www.iqvia.com/locations/middle-east-and-africa">Middle East and Africa</a></li> </ul> <ul class="sub-list" style="float:left"> </ul> </div> <div class="regional-promoted mobile"> <div class="w-65"> <div class="w-33"> <div class="card-wrapper"> <div class="card"> <img src="/-/media/iqvia/images/modules/brandworld/2093_analyzing-data-using-big-screen-display-and-laptop.png?h=576&amp;w=1024&amp;hash=DD78C1BEF3450AEE5A9B46042BB116EB"> <h5 class="title">EMEA Thought Leadership</h5> <p class="description">Developing IQVIA’s positions on key trends in the pharma and life sciences industries, with a focus on EMEA.</p> <a class="hover-color-blue-with-anim" href="https://www.iqvia.com/locations/emea/emea-thought-leadership"> Learn more <div class="icon"> 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href="https://www.iqvia.com/solutions/safety-regulatory-compliance">Safety &amp; Regulatory Compliance</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li class="tab-title cursor-pointer d-flex align-center"> <a class="list-item-style text-decoration-none after-none" href="https://www.iqvia.com/solutions/technologies">Technologies</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> </ol> </div> <div class="w-80 tab-content remove-last solutions"> <div class="item h-100 default-content mt-0"> <div class="w-22 "> <h5 class="">LIFE SCIENCE SEGMENTS</h5> <ol> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/consumer-health">Consumer Health</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/emerging-biopharma">Emerging Biopharma</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/generics">Generics</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/medtech">MedTech</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/pharmaceutical-manufacturers">Pharmaceutical Manufacturers</a></li> </ol> </div> <div class="w-22 "> <h5 class="">HEALTHCARE SEGMENTS</h5> <ol> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/information-partner-services">Information Partner Services</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/financial-institutions">Financial Institutions</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/commitment-to-public-health">Global Public Health</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/public-health-and-government">Government</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/patient-associations">Patient Associations</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/payers">Payers</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/industry-segments/providers">Providers</a></li> </ol> </div> <div class="w-22 "> <h5 class="">THERAPEUTIC AREAS</h5> <ol> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/cardiovascular">Cardiovascular</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/cell-and-gene-therapy">Cell and Gene Therapy</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/central-nervous-system">Central Nervous System</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/gi-and-hepatology">GI &amp; Hepatology</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/infectious-diseases-and-vaccines">Infectious Diseases and Vaccines</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/oncology">Oncology</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/pediatrics">Pediatrics</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics/rare-diseases">Rare Diseases</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/solutions/therapeutics#viewall">View All</a></li> </ol> </div> <div class="w-34 full-bg"> <div class="card-wrapper "> <div class="card"> <img src="/-/media/iqvia/images/our-impact/our-impact.jpeg?h=720&amp;w=1280&amp;hash=83684E8436D9E61011F7A8186B9E33E3"> <h5 class="title">Impacting People&#39;s Lives</h5> <p class="description">We strive to help improve outcomes and create a healthier, more sustainable world for people everywhere.</p> <a class="hover-color-blue-with-anim" href="https://www.iqvia.com/about-us/our-impact"> LEARN MORE <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 "> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/rdssolutionartwhite_outlines.png?h=600&amp;w=600&amp;hash=2951AF0F5AF13EB584FD90B004210E65"> </div> <div class="w-33"> <h3>Harness the power to transform clinical development</h3> <p>Reimagine clinical development by intelligently connecting data, technology, and analytics to optimize your trials. The result? Faster decision making and reduced risk so you can deliver life-changing therapies faster.</p> <a class="btn" href="https://www.iqvia.com/solutions/research-and-development" style="max-width: 303px;">Research &amp; Development Overview</a> </div> <div class="w-33"> <h6 class="pt-0 border-left pb-11 mt-0">Research &amp; Development Quick Links</h6> <ol class="border-left"> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/research-and-development/clinical-trials">Clinical Trials</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/research-and-development/functional-services">Functional Services</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/research-and-development/decentralized-trials">Decentralized Trials</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/research-and-development/consulting">Consulting</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/therapeutics">Therapeutic Expertise</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/research-and-development/site-and-investigators">Site and Investigators</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/research-and-development/global-laboratories">Global Laboratories</a></li> </ol> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 "> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/rwesolutionartwhite_outlines.png?h=600&amp;w=600&amp;hash=F6C2B1387FB0C98A6EA794984CB85B6B"> </div> <div class="w-33"> <h3>Real World Evidence. Real Confidence. Real Results.</h3> <p>Generate and disseminate evidence that answers crucial clinical, regulatory and commercial questions, enabling you to drive smarter decisions and meet your stakeholder needs with confidence.</p> <a class="btn" href="https://www.iqvia.com/solutions/real-world-evidence" style="max-width: 303px;">REAL WORLD EVIDENCE OVERVIEW</a> </div> <div class="w-33"> <h6 class="pt-0 border-left pb-11 mt-0">Real World Evidence Quick Links</h6> <ol class="border-left"> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/real-world-data-and-insights">Real World &amp; Health Data Sets</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/medical-affairs">Medical Affairs</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai">Health Data Apps &amp; AI</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-transformation">Health Data Transformation</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/study-design">Study Design</a></li> </ol> <ol class="border-left"> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/evidence-networks">Evidence Networks</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-economics-and-value">Health Economics &amp; Value</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/regulatory-and-safety">Regulatory and Safety</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/iqvia-nlp-platform">Natural Language Processing</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/insights">Real World Evidence Library</a></li> </ol> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 "> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/commercializationsolutionartwhite_outlines.png?h=600&amp;w=601&amp;hash=87F88AAD474D46B8E87146822C57D5E3"> </div> <div class="w-33"> <h3>See markets more clearly. Opportunities more often.</h3> <p>Elevate commercial models with precision and speed using AI-driven analytics and technology that illuminate hidden insights in data.</p> <a class="btn" href="https://www.iqvia.com/solutions/commercialization" style="max-width: 303px;">COMMERCIALIZATION OVERVIEW</a> </div> <div class="w-33"> <h6 class="pt-0 border-left pb-11 mt-0">Commercialization Quick Links</h6> <ol class="border-left"> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/covid-19-and-commercialization">COVID-19 &amp; Commercialization</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/launch-strategy-and-management">Launch Strategy &amp; Management</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/brand-strategy-and-management">Brand Strategy &amp; Management</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/pricing-and-market-access">Pricing &amp; Market Access</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/healthcare-professional-engagement">Healthcare Professional Engagement</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/patient-engagement-and-support">Patient Engagement and Support</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/promotional-strategy">Promotional Strategy</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/established-brands-optimization">Established Brands Optimization</a></li> </ol> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 "> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/compliancesolutionartwhite_outlines.png?h=600&amp;w=600&amp;hash=B1920C3D73F8BBBB31B381CAE5BBE75F"> </div> <div class="w-33"> <h3>Service driven. Tech-enabled. Integrated compliance.</h3> <p>Orchestrate your success across the complete compliance lifecycle with best-in-class services and solutions for safety, regulatory, quality and medical information.</p> <a class="btn" href="https://www.iqvia.com/solutions/safety-regulatory-compliance" style="max-width: 303px;">COMPLIANCE OVERVIEW</a> </div> <div class="w-33"> <h6 class="pt-0 border-left pb-11 mt-0">Safety &amp; Regulatory Compliance Quick Links</h6> <ol class="border-left"> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/safety-and-pharmacovigilance">Safety Pharmacovigilance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/regulatory-compliance">Regulatory Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/quality-compliance">Quality Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/medical-information">Medical Information</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/commercial-compliance">Commercial Compliance</a></li> </ol> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 "> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/techsolutionartwhite_outlines.png?h=600&amp;w=600&amp;hash=3F741080B4AA6100EAE1111FB0649C08"> </div> <div class="w-33"> <h3>Intelligence that transforms life sciences end-to-end.</h3> <p>When your destination is a healthier world, making intelligent connections between data, technology, and services is your roadmap.</p> <a class="btn" href="https://www.iqvia.com/solutions/technologies" style="max-width: 303px;">TECHNOLOGIES OVERVIEW</a> </div> <div class="w-33"> <h6 class="pt-0 border-left pb-11 mt-0">Technology Quick Links</h6> <ol class="border-left"> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials">Orchestrated Clinical Trials</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/information-management">Enterprise Information Management</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/performance-management-and-insights">Performance Management &amp; Insights</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/healthcare-professional-engagement/onekey/onekey-hcp-reference-data">Provider Reference Data Network</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/customer-engagement">Customer Engagement</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/commercial-compliance">Commercial Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/safety-regulatory-and-quality">Safety, Regulatory, Quality Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/developer">Developer</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/partner-programs">Partner Programs</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/insights">Technology Insights</a></li> </ol> </div> </div> </div> </div> </div> </div> </div> </div> </div> </li> <li> <a class="color-white" href="#">Products</a> <div class="primary-nav-wrapper"> <div class="content product-selector"> <div class="shadow"></div> <div class="d-flex remove-last"> <div class="w-22 pt-35 pb-35"> <h5 class="">CLINICAL PRODUCTS</h5> <ol> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/planning-suite">Planning Suite</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/planning-suite/grantplan">Grant Plan</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/digital-site-suite">Site Suite</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/digital-site-suite/clinical-trial-payments">Clinical Trial Payments</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/digital-site-suite/investigator-site-portal">Investigator Site Portal</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/digital-site-suite/one-home-for-sites">One Home for Sites</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/patient-engagement-suite">Patient Engagement Suite</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/patient-engagement-suite/ecoa">Electronic Clinical Outcome Assessment (eCOA)</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/patient-engagement-suite/interactive-response-technology">Interactive Response Technology (IRT)</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/orchestrated-clinical-trials/clinical-data-analytics-solutions">Clinical Data Analytics Solutions</a></li> </ol> </div> <div class="w-22 pt-35 pb-35"> <h5 class="">COMMERCIAL PRODUCTS</h5> <ol> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/information-management">Information Management</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/launch-strategy-and-management">Launch Strategy &amp; Management</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/pricing-and-market-access">Pricing &amp; Market Access</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/brand-strategy-and-management">Brand Strategy &amp; Management</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/promotional-strategy">Promotional Engagement</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/performance-management-and-insights">Performance Management &amp; Insights</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/performance-management-and-insights/orchestrated-analytics">Orchestrated Analytics</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/performance-management-and-insights/orchestrated-analytics/next-best">Next Best Action</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/technologies/customer-engagement">Customer Engagement (OCE)</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/commercialization/patient-engagement-and-support">Patient Engagement and Support</a></li> </ol> </div> <div class="w-22 pt-35 pb-35"> <h5 class="">COMPLIANCE, SAFETY, REG PRODUCTS</h5> <ol> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/safety-and-pharmacovigilance/iqvia-vigilance-platform">IQVIA Vigilance Platform</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/commercial-compliance">Commercial Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/regulatory-compliance">Regulatory Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/regulatory-compliance/iqvia-rim-smart">RIM Smart</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/quality-compliance">Quality Compliance</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/quality-compliance/smartsolve-eqms">SmartSolve eQMS</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/safety-regulatory-compliance/safety-and-pharmacovigilance">Safety &amp; Pharmacovigilance</a></li> </ol> </div> <div class="w-22 pt-35 pb-35"> <h5 class="">REAL WORLD PRODUCTS</h5> <ol> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai">Health Data Apps &amp; AI</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai/analytics-research-accelerator">Analytics Research Accelerator​</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai/expert-ecosystem">Expert Ecosystem​</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai/ai-driven-hcp-and-patient-profiling-commercial">AI Patient &amp; HCP Profiling- Commercial</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai/ai-driven-patient-and-provider-profiling">AI Patient &amp; Provider Profiling- Med Affairs​</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai/ai-driven-hcp-and-patient-profiling">AI Patient &amp; HCP Profiling- Healthcare​</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/iqvia-nlp-platform">Natural Language Processing</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/health-economics-and-value/market-access-insights">Market Access Insights</a></li> <li class="hover-color-blue"><a href="https://www.iqvia.com/solutions/real-world-evidence/study-design/health-research-space">Direct-to-Patient Research</a></li> </ol> </div> <div class="w-28 "> <div class="card-wrapper h-100"> <div class="card"> <img src="/-/media/iqvia/images/modules/brandworld/2121_business-woman-using-dashboard-on-screen.png?h=683&amp;w=1024&amp;hash=598F2F336961970EA76EED465B050DDE"> <h5 class="title">CASE STUDY</h5> <p class="description">Data in a Day</p> <a class="hover-color-blue-with-anim" href="https://www.iqvia.com/library/case-studies/data-in-a-day"> LEARN MORE <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" 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">FEATURED INNOVATIONS</h5> <ol class="solution-tabs "> <li class="tab-title cursor-pointer d-flex align-center"> <a class="list-item-style text-decoration-none after-none" href="https://www.iqvia.com/about-us/iqvia-connected-intelligence">IQVIA Connected Intelligence™</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li class="tab-title cursor-pointer d-flex align-center"> <a class="list-item-style text-decoration-none after-none" href="https://www.iqvia.com/solutions/innovative-models/artificial-intelligence-and-machine-learning">IQVIA Healthcare-grade AI™</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li class="tab-title cursor-pointer d-flex align-center"> <a class="list-item-style text-decoration-none after-none" href="https://www.iqvia.com/solutions/innovative-models/artificial-intelligence-and-machine-learning/iqvia-ai-assistant">IQVIA AI Assistant</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" 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href="https://www.iqvia.com/solutions/research-and-development/decentralized-trials">Decentralized Trials</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li class="tab-title cursor-pointer d-flex align-center"> <a class="list-item-style text-decoration-none after-none" href="https://www.iqvia.com/about-us/iqvia-patient-experience-solutions-with-apple-devices">Patient Experience Solutions with Apple devices</a> <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> </ol> </div> <div class="w-80 tab-content about"> <div class="item h-100 default-content mt-0"> <div class="w-33 pb-35 "> <h5 class="">WHO WE ARE</h5> <ol> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us">Our Story</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/our-impact">Our Impact</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/commitment-to-public-health">Commitment to Public Health</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/code-of-conduct">Code of Conduct</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/esg">Environmental Social Governance</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/privacy">Privacy</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/leadership">Executive Team</a></li> </ol> </div> <div class="w-33 pb-35 "> <h5 class="">NEWS &amp; RESOURCES</h5> <ol> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/newsroom">News</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/events">Events &amp; Webinars</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/analyst-reports">Industry Analyst Reports</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/about-us/commitment-to-public-health/covid-19-resources">COVID-19 Resources</a></li> <li class="hover-color-blue"><a class=white-space-no-wrap text-decoration-none href="https://www.iqvia.com/locations">Our Locations</a></li> </ol> </div> <div class="w-33 "> <div class="card-wrapper "> <div class="card"> <img src="/-/media/iqvia/images/navigation/354_professional-man-leading-meeting-in-office-cubicle.jpg?h=683&amp;w=1024&amp;hash=1A73E77D3E5A169DFFAB2A49CB369CB3"> <h5 class="title">INVESTOR RELATIONS</h5> <p class="description">Visit our investor relations site for more information.</p> <a class="hover-color-blue-with-anim" href="https://ir.iqvia.com/overview/default.aspx"> LEARN MORE <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/homepagehero_ci.png?h=1058&amp;w=1200&amp;hash=E6F7621F8CB48BC6EA4D48B02F63F8E1"> </div> <div class="w-33"> <h3>Unlock your potential to drive healthcare forward</h3> <p>By making intelligent connections between your needs, our capabilities, and the healthcare ecosystem, we can help you be more agile, accelerate results, and improve patient outcomes.</p> <a class="btn" href="https://www.iqvia.com/about-us/iqvia-connected-intelligence" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/modules/brandworld/2767_portrait-of-two-engineers-using-laptop-casually-chatting-in-high-tech-research.png?h=540&amp;w=1024&amp;hash=6EE14B9365C7977C3B07A43B65C71B45"> </div> <div class="w-33"> <h3>IQVIA AI is Healthcare-grade AI</h3> <p>Building on a rich history of developing AI for healthcare, IQVIA AI connects the right data, technology, and expertise to address the unique needs of healthcare. It&#39;s what we call Healthcare-grade AI.</p> <a class="btn" href="https://www.iqvia.com/solutions/innovative-models/artificial-intelligence-and-machine-learning" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/body/innovative-models/ai-and-ml/aiassistant5050-navigation.png?h=561&amp;w=1024&amp;hash=A5A0A22E730320705E76550143802F4C"> </div> <div class="w-33"> <h3>Meet the IQVIA AI Assistant </h3> <p>Your new expert analyst is here. Be at the forefront of data-driven decision-making with a new generative AI tool that enables you to interact with our products and solutions like never before. Get results you can trust, faster.</p> <a class="btn" href="https://www.iqvia.com/solutions/innovative-models/artificial-intelligence-and-machine-learning/iqvia-ai-assistant" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/blogs/2116_abstract-background-with-luminous-particles.jpg?h=675&amp;w=1200&amp;hash=6102399574165D0ABCB89791A890BF2D"> </div> <div class="w-33"> <h3>Your healthcare data deserves more than just a cloud.</h3> <p>The IQVIA Human Data Science Cloud is our unique capability designed to enable healthcare-grade analytics, tools, and data management solutions to deliver fit-for-purpose global data at scale.</p> <a class="btn" href="https://www.iqvia.com/solutions/human-data-science-cloud" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/innovationhubheroimage.png?h=3175&amp;w=3375&amp;hash=03A3A2DB1F3EFF368CD63BA86426159D"> </div> <div class="w-33"> <h3>Innovations make an impact when bold ideas meet powerful partnerships</h3> <p>The IQVIA Innovation Hub connects start-ups with the extensive IQVIA network of assets, resources, clients, and partners. Together, we can help lead the future of healthcare with the extensive IQVIA network of assets, resources, clients, and partners.</p> <a class="btn" href="https://www.iqvia.com/about-us/innovation-hub" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/navigation/208_woman-using-tablet-on-sofa-cropped_600.jpg?h=683&amp;w=1024&amp;hash=113B49B766D4F49F5E147F481F8316EA"> </div> <div class="w-33"> <h3>Proven, faster DCT solutions</h3> <p>IQVIA Decentralized Trials deliver purpose-built clinical services and technologies that engage the right patients wherever they are. Our hybrid and fully virtual solutions have been used more than any others.</p> <a class="btn" href="https://www.iqvia.com/solutions/research-and-development/decentralized-trials" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> <div class="item bg h-100 align-center"> <div class="d-flex align-center w-100 no-links"> <div class="w-33"> <img src="/-/media/iqvia/images/apple/applewatchpatient.png?h=683&amp;w=1024&amp;hash=E32CDCB8BE1C8513D26ACAADA5B282A9"> </div> <div class="w-33"> <h3>IQVIA Patient Experience Solutions with Apple devices</h3> <p>Empowering patients to personalize their healthcare and connecting them to caregivers has the potential to change the care delivery paradigm.</p> <a class="btn" href="https://www.iqvia.com/about-us/iqvia-patient-experience-solutions-with-apple-devices" style="max-width: 303px;">LEARN MORE</a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </li> <li> <a class="color-white" href="#">Careers</a> <div class="primary-nav-wrapper"> <div class="content careers"> <div class="shadow"></div> <div class="d-flex "> <div class="w-50"> <div class="d-flex pt-75"> <div class="w-50"> <h5>WORKING AT IQVIA</h5> <p>Our mission is to accelerate innovation for a healthier world. Together, we can solve customer challenges and improve patient lives.</p> <a class="hover-color-blue-with-anim" href="https://jobs.iqvia.com/"> LEARN MORE <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> <div class="w-50"> <h5>LIFE AT IQVIA</h5> <p>Careers, culture and everything in between. Find out what’s going on right here, right now.</p> <a class="hover-color-blue-with-anim" href="https://jobs.iqvia.com/blog"> LEARN MORE <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> </div> </div> <div class="w-50 pr-10 "> <div class="card-wrapper"> <div class="card d-flex"> <div class="d-flex flex-column min-with-description"> <h5 class="title">WE’RE HIRING</h5> <p class="description">Improving human health requires brave thinkers who are willing to explore new ideas and build on successes. Unleash your potential with us.</p> <a class="hover-color-blue-with-anim" href="https://jobs.iqvia.com/search-jobs"> SEARCH JOBS <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> <img src="/-/media/iqvia/images/navigation/website-featured_jpg-2213_cheerful-young-colleagues-using-laptop.jpg?h=683&amp;w=1024&amp;hash=D776A849F30494AB90F889BBB8F30041"> </div> </div> </div> </div> </div> </div> </li> </ol> <div class="overlay"></div> <div class="btn-style btn-primary-nav"> <a class="cta-btn-redesign" href="#rfp"> <span class="tile">Contact Us</span> <div class="arrow-wrapper"> <span class="line"></span> <span class="line"></span> </div> </a> </div> </nav> </div> </div> <div class="mobile-overlay mobile-navigation-overlay"> <div class="overlay-content"> <div class="top-nav"> <nav role="Secondary"> <button role="button" data-type="regions">REGIONS<img src="https://www.iqvia.com/Content/Shotgun/img/globe.svg"></button> <button role="button" data-type="search">Search<img src="https://www.iqvia.com/Content/Shotgun/img/search.svg"></button> </nav> </div> <div class="main-nav"> <ol role="Primary"> <li data-item="solutions"><a>Solutions</a></li> <li data-item="products"><a>Products</a></li> <li data-item="insights"><a>Insights</a></li> <li data-item="about"><a>About</a></li> <li data-item="careers"><a>Careers</a></li> <li class="external-style"><a class="nav-mobile-contact-us" href="#rfp">Contact Us</a></li> </ol> </div> <div class="mobile-content"> <div class="item-wrapper-mobile search-mobile" data-attribute="search"> <div class="breadcrumbs go-to-main"><span class="go-main">MAIN</span>/<span>search</span></div> <div class="field-group"> <img width="20" src="https://www.iqvia.com/Content/Shotgun/img/search.svg"> <input placeholder="How can we help?"> </div> <div class="btn-search"> <button>search</button> </div> </div> <div class="item-wrapper-mobile list solutions" data-attribute="solutions"> <div class="breadcrumbs"><span class="go-home">MAIN</span>/<span>Solutions</span></div> <div class="breadcrumbs d-none" style="padding-bottom:30px;"><span class="go-main">Solutions</span>/<span></span></div> <div class="content action-list"> <h6 class="mt-0">SOLUTIONS</h6> <ul class="click-action"> <li> Research &amp; Development <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li> Real World Evidence <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li> Commercialization <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li> Safety &amp; Regulatory Compliance <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li> Technologies <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> </ul> <h6 class="mt-0">LIFE SCIENCE SEGMENTS</h6> <ul> <li><a href="https://www.iqvia.com/solutions/industry-segments/consumer-health">Consumer Health</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/emerging-biopharma">Emerging Biopharma</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/generics">Generics</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/medtech">MedTech</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/pharmaceutical-manufacturers">Pharmaceutical Manufacturers</a></li> </ul> <h6 class="mt-0">HEALTHCARE SEGMENTS</h6> <ul> <li><a href="https://www.iqvia.com/solutions/industry-segments/information-partner-services">Information Partner Services</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/financial-institutions">Financial Institutions</a></li> <li><a href="https://www.iqvia.com/about-us/commitment-to-public-health">Global Public Health</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/public-health-and-government">Government</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/patient-associations">Patient Associations</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/payers">Payers</a></li> <li><a href="https://www.iqvia.com/solutions/industry-segments/providers">Providers</a></li> </ul> <h6 class="mt-0">THERAPEUTIC AREAS</h6> <ul> <li><a href="https://www.iqvia.com/solutions/therapeutics/cardiovascular">Cardiovascular</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/cell-and-gene-therapy">Cell and Gene Therapy</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/central-nervous-system">Central Nervous System</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/gi-and-hepatology">GI &amp; Hepatology</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/infectious-diseases-and-vaccines">Infectious Diseases and Vaccines</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/oncology">Oncology</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/pediatrics">Pediatrics</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics/rare-diseases">Rare Diseases</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics#viewall">View All</a></li> </ul> <div class="card-wrapper"> <div class="card"> <img src="/-/media/iqvia/images/our-impact/our-impact.jpeg?h=720&amp;w=1280&amp;hash=83684E8436D9E61011F7A8186B9E33E3"> <h4 class="mt-30">Impacting People&#39;s Lives</h4> <p>"We strive to help improve outcomes and create a healthier, more sustainable world for people everywhere.</p> <a class="btn-redirect" href="https://www.iqvia.com/about-us/our-impact" target="_blank"> LEARN MORE <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> </div> </div> <div class="tabs"> <div class="tab-item"> <img src="/-/media/iqvia/images/navigation/rdssolutionartwhite_outlines.png?h=600&amp;w=600&amp;hash=2951AF0F5AF13EB584FD90B004210E65"> <h5>Harness the power to transform clinical development</h5> <p>Reimagine clinical development by intelligently connecting data, technology, and analytics to optimize your trials. The result? Faster decision making and reduced risk so you can deliver life-changing therapies faster.</p> <a class="btn" href="https://www.iqvia.com/solutions/research-and-development">Research &amp; Development Overview</a> <div class="hr"></div> <h6>Research &amp; Development Quick Links</h6> <ul> <li><a href="https://www.iqvia.com/solutions/research-and-development/clinical-trials">Clinical Trials</a></li> <li><a href="https://www.iqvia.com/solutions/research-and-development/functional-services">Functional Services</a></li> <li><a href="https://www.iqvia.com/solutions/research-and-development/decentralized-trials">Decentralized Trials</a></li> <li><a href="https://www.iqvia.com/solutions/research-and-development/consulting">Consulting</a></li> <li><a href="https://www.iqvia.com/solutions/therapeutics">Therapeutic Expertise</a></li> <li><a href="https://www.iqvia.com/solutions/research-and-development/site-and-investigators">Site and Investigators</a></li> <li><a href="https://www.iqvia.com/solutions/research-and-development/global-laboratories">Global Laboratories</a></li> </ul> </div> <div class="tab-item"> <img src="/-/media/iqvia/images/navigation/rwesolutionartwhite_outlines.png?h=600&amp;w=600&amp;hash=F6C2B1387FB0C98A6EA794984CB85B6B"> <h5>Real World Evidence. Real Confidence. Real Results.</h5> <p>Generate and disseminate evidence that answers crucial clinical, regulatory and commercial questions, enabling you to drive smarter decisions and meet your stakeholder needs with confidence.</p> <a class="btn" href="https://www.iqvia.com/solutions/real-world-evidence">REAL WORLD EVIDENCE OVERVIEW</a> <div class="hr"></div> <h6>Real World Evidence Quick Links</h6> <ul> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/real-world-data-and-insights">Real World &amp; Health Data Sets</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/medical-affairs">Medical Affairs</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-apps-and-ai">Health Data Apps &amp; AI</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/health-data-transformation">Health Data Transformation</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/study-design">Study Design</a></li> </ul> <ul> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/evidence-networks">Evidence Networks</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/health-economics-and-value">Health Economics &amp; Value</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/regulatory-and-safety">Regulatory and Safety</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/iqvia-nlp-platform">Natural Language Processing</a></li> <li><a href="https://www.iqvia.com/solutions/real-world-evidence/insights">Real World Evidence Library</a></li> </ul> </div> <div class="tab-item"> <img src="/-/media/iqvia/images/navigation/commercializationsolutionartwhite_outlines.png?h=600&amp;w=601&amp;hash=87F88AAD474D46B8E87146822C57D5E3"> <h5>See markets more clearly. 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list about" data-attribute="about"> <div class="breadcrumbs"><span class="go-home">MAIN</span>/<span>About</span></div> <div class="breadcrumbs d-none" style="padding-bottom:30px;"><span class="go-main">About</span>/<span></span></div> <div class="content action-list"> <h6 class="mt-15">FEATURED INNOVATIONS</h6> <ul class="click-action"> <li> IQVIA Connected Intelligence™ <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </li> <li> IQVIA Healthcare-grade AI™ <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" 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Unleash your potential with us.</p> <a class="btn-redirect" href="https://jobs.iqvia.com/search-jobs" target="_blank"> SEARCH JOBS <div class="icon"> <svg xmlns="http://www.w3.org/2000/svg" width="7.029" height="12" viewBox="0 0 7.029 12"> <g id="Chevron" transform="translate(-135.26 -19.823)"> <rect id="Rectangle_125" data-name="Rectangle 125" width="8.521" height="1.42" rx="0.71" transform="translate(136.264 19.823) rotate(45)" fill="#959ca0"></rect> <rect id="Rectangle_126" data-name="Rectangle 126" width="8.521" height="1.42" rx="0.71" transform="translate(135.26 30.819) rotate(-45)" fill="#959ca0"></rect> </g> </svg> </div> </a> </div> </div> </div> <div class="item-wrapper-mobile list " data-attribute="contactus"> <div class="breadcrumbs"><span class="go-home">MAIN</span>/<span>Contact Us</span></div> <div class="breadcrumbs d-none" style="padding-bottom:30px;"><span class="go-main">Contact Us</span>/<span></span></div> <div class="lists"> </div> </div> </div> </div> </div> </div> </header> <!-- END NOINDEX --> <section class="insights-detail-hero-redesign charcoal__bg"> <div class="insights-detail-hero-outer"> <div class="insights-detail-hero-outer-top"> <div class="insights-detail-hero-outer-content"> <div class="top-part">Blog</div> <div class="title">Unmet clinical needs drive patient interest in clinical trial participation in Major Depressive Disorder</div> <div class="date"> <div class="author"> <div>Meike Madelung, Engagement Manager EMEA Thought Leadership</div> <div>Brigida Chaves, Associate Director Patient Advocacy CoE, EMEA</div> </div> <div class="time">Oct 03, 2024</div> </div> </div> </div> <div class="hero-breadcrumbs padding z_index breadcrumbs-hero_outer"> <div class="breadcrumbs breadcrumbs-hero_inner"> <ul class="breadcrumbs__list"> <li class="breadcrumbs__item"> <a href="https://www.iqvia.com/"><span class="iqvia-icon-home"></span></a> </li> <li class="breadcrumbs__item"> <a href="https://www.iqvia.com/blogs">Blogs</a> </li> <li class="breadcrumbs__item"> <span>Unmet clinical needs drive patient interest in clinical trial participation in Major Depressive Disorder</span> </li> </ul> </div> </div> </div> </section> <section class="share-bar-redesign"> <div class="share-bar-wrapper"> <button class="share-bar-container"> <p> Share PAGE <img alt="Share PAGE" src="/Content/Shotgun/img/icons/social_icons/new/Share.svg" /> </p> <ul class="dropdown"> <li title="Copy link to clipboard" data-event="copy"> <span>Copy Link</span> <img src="/Content/Shotgun/img/icons/social_icons/new/Copy.svg" /> </li> </ul> </button> </div> </section> <section class="insights-detail-body-redesign "> <div class="insights-detail-body-redesign__outer"> <div class="insights-detail-body-redesign__inner"> <h5><span><strong>Rising burden of disease</strong></span></h5> <p><span>Depressive disorders are among the most prevalent conditions globally and the associated burden of disease is growing. For many people these are life-altering, chronic conditions which not only affect every aspect of their daily lives but can also have considerable impact on their loved ones.</span></p> <p><span>The WHO estimates the global impact of depressive disorders at 57m Disability-adjusted life years (DALYs) in 2021, putting them in 13<sup style="line-height:10px;font-size:12px;">th</sup> place, up from 37m DALYs and rank 19 in 2000.<sup style="font-size:12px;line-height:10px;">1</sup> In part at least this increase is associated with the COVID-19 pandemic - according to the WHO, the number of people suffering from depression and anxiety went up by 25% in the first year of the pandemic alone<sup style="font-size:12px;line-height:10px;">2</sup>.</span></p> <p><span>Global spending on mental health medication is also expected to increase in the next years. The figure currently stands at 81bn USD, with a projected 9-12% CAGR until 2028, exceeding the projected total market growth of 5-8%<sup style="font-size:12px;line-height:10px;">3</sup>. There is also considerable potential for future innovative therapies: although trial starts in 2023 were below the pre-pandemic level, there are currently nearly 250 ongoing trials covering a wide range of MoAs<sup style="font-size:12px;line-height:10px;">4</sup>.</span></p> <p><span>However, pharmaceutical treatment is only part of the picture in managing Major Depressive Disorder (MDD). People affected by MDD also benefit from psychotherapy and supportive complementary treatments like meditation or sports to improve overall well-being. Support programmes for patients with a focus on self-efficacy and reducing self-stigma can also be helpful. Overall, though, there is still considerable unmet need.</span></p> <p><span>IQVIA partnered with patient organisation MQ Mental Health Research to conduct a survey of people living with MDD to discover which difficulties they encounter in the course of diagnosis, treatment, and adjusting to living with the disease and where they could benefit from additional support. The survey consisted of in-depth interviews with six participants with moderately severe to severe MDD based in the UK, the US, and Spain.</span></p> <br /> <p><span>The information provided in these interviews reflects both the pervasive impact of MDD and the considerable unmet needs in treating and managing it.</span></p> <br /> <h5><span><strong>Unmet clinical need drives motivation to participate in clinical trials</strong></span></h5> <p><span>With regard to pharmaceutical treatment, patients report that finding a helpful pharmaceutical regime is challenging since it often involves a combination of drugs, for instance anti-depressants combined with anti-anxiety medication. They are also often unhappy with the side effects of antidepressants which they describe as &ldquo;numbing&rdquo; or making them feel &ldquo;like a zombie&rdquo; but do not restore the lost feeling of well-being or the ability to function in day-to-day life. In addition, the medication is not effective immediately but takes some time to build up which can make it difficult to disentangle which changes in a patient&rsquo;s condition are the result of medication or of other interventions.</span></p> <p><span>Psychotherapy is perceived as helpful, but people often experience barriers to access &ndash; sometimes other doctors do not want to refer the patient, there may be no therapists available in a reasonable timeframe, or psychotherapy is not covered by the patient&rsquo;s insurance. It can also take time to build up trust and sometimes several tries to find a therapist with whom the patient feels comfortable.</span></p> <p><span>The lack of efficacious pharmaceuticals experienced by the patients IQVIA spoke to drives a willingness to participate in clinical studies provided certain conditions are met. For these patients, the prospect of getting early access to new therapies which might improve their overall condition is a key reason to consider clinical trials. It is however imperative that potential participants feel well informed and well taken care of. Information needs to centre around understanding the medication being tested, what possible side effects there are and the potential outcomes. Information about the logistics of the trial and what is being expected of the participants is also essential. It is important that this information is delivered by the participants&rsquo; own HCP or by clinical trial staff in a sensitive, empathic manner, with enough time taken to answer questions. Booklets for follow-up are also valuable.</span></p> <p><span>In designing clinical trials, the severe impact of MDD on people&rsquo;s executive function must be taken into account. Issues such as fatigue, brain fog, lack of motivation and organisation, social anxiety and similar topics are very commonly reported. In order to ensure participants&rsquo; adherence and compliance, practical and motivational support must be ensured to overcome these barriers.</span></p> <p><span>The motivation for participating in real world studies and for sharing data is somewhat lower than for participating in clinical trials. This is largely due to a lack of understanding of the purpose and value of RWE studies and a reluctance to share confidential and often very personal insights into their emotional and mental state with people they do not know and have no opportunity to establish a trust-based relationship with. The potential benefit of gaining early access to new therapies is also lacking. This reluctance could potentially be overcome by building awareness about the benefit of RWE studies and cultivating relationships with patient communities.</span></p> <br /> <h5><span><strong>An opening for pharma</strong></span></h5> <p><span>There is also an opportunity for pharma to step into the gap where patient support is concerned &ndash; interview partners report that they rely primarily on their families and people close to them for practical and psychological support. Further sources are social media and patient support groups where experiences and information can be shared. Pharma, on the other hand, is not perceived as being in the business of supporting patients &ndash; &ldquo;that&rsquo;s not what they do, is it?&rdquo;</span></p> <p><span>Given the unmet need reported in terms of information and guidance on managing life with MDD and also the challenges outlined above in informing and motivating patients to participate in clinical trials and share data for RWE studies, there is some potential here for pharma to tap provided they step carefully and focus on building relationships with the patient community based on respect and trust. Building and nurturing such support systems could benefit patients by helping them better understand and manage their condition, and pharma by improving patient compliance and adherence through better expectation management as well as participation in clinical trials and RWE studies.</span></p> <div><br clear="all" /> <hr align="left" size="1" width="33%" /> <div id="edn1"> <p style="font-size:12px;"><sup>1</sup><span> <a rel="noopener noreferrer" href="https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys" target="_blank">https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/global-health-estimates-leading-causes-of-dalys</a> , accessed Sep 18, 2024</span></p> </div> <div id="edn2"> <p style="font-size:12px;"><sup>2</sup><span> <a rel="noopener noreferrer" href="https://www.who.int/publications/i/item/9789240050860" target="_blank">World mental health report: Transforming mental health for all - executive summary (who.int)</a></span></p> </div> <div id="edn3"> <p style="font-size:12px;"><sup>3</sup><span> Source: IQVIA Institute for Human Data Science. Global Use of Medicines: Outlook to 2028, January 2024. <a rel="noopener noreferrer" href="https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/the-global-use-of-medicines-2024-outlook-to-2028" target="_blank">https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/the-global-use-of-medicines-2024-outlook-to-2028</a> </span></p> </div> <div id="edn4"> <p style="font-size:12px;"><sup>4</sup><span> Source: IQVIA Institute for Human Data Science. Global Trends in R&amp;D 2024: Activity, Productivity, and Enablers. February 2024. <a rel="noopener noreferrer" href="https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2024-activity-productivity-and-enablers" target="_blank">https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2024-activity-productivity-and-enablers</a> </span></p> </div> </div> </div> </div> </section> <section id="RelatedSolutions"></section> <section class="multi-card__carousel-redesign init-js-related"> <div class="multi-card__outer"> <div class="multi-card__wrapper"> <div class="multi-card__inner"> <h2 class="eyebrow"> You may also be interested in </h2> <div class="swiper swiper-container"> <div class="swiper-wrapper"> <div class="swiper-slide"> <div class="card-item card-link"> <a href="https://www.iqvia.com/locations/emea/blogs/2024/11/in-depth-patient-insights-in-obesity-highlight" target="_self"> <div class="img" style="background-image: 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