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var(--bs-nav-link-padding-x);font-size:var(--bs-nav-link-font-size);font-weight:var(--bs-nav-link-font-weight);color:var(--bs-nav-link-color)}.nav-fill .nav-item{flex:1 1 auto;text-align:center}.nav-fill .nav-item .nav-link{width:100%}.navbar{--bs-navbar-padding-x:0;--bs-navbar-padding-y:0.5rem;--bs-navbar-color:rgba(0, 0, 0, 0.55);--bs-navbar-hover-color:rgba(0, 0, 0, 0.7);--bs-navbar-disabled-color:rgba(0, 0, 0, 0.3);--bs-navbar-active-color:rgba(0, 0, 0, 0.9);--bs-navbar-brand-padding-y:0.25rem;--bs-navbar-brand-margin-end:1rem;--bs-navbar-brand-font-size:1.25rem;--bs-navbar-brand-color:rgba(0, 0, 0, 0.9);--bs-navbar-brand-hover-color:rgba(0, 0, 0, 0.9);--bs-navbar-nav-link-padding-x:0.5rem;--bs-navbar-toggler-padding-y:0.25rem;--bs-navbar-toggler-padding-x:0.75rem;--bs-navbar-toggler-font-size:1.25rem;--bs-navbar-toggler-icon-bg:url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='rgba%280, 0, 0, 0.55%29' stroke-linecap='round' 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var(--bs-navbar-padding-x);background-image:var(--bs-gradient)}.navbar>.container,.navbar>.container-fluid{display:flex;flex-wrap:inherit;align-items:center;justify-content:space-between}.navbar-brand{padding-top:var(--bs-navbar-brand-padding-y);padding-bottom:var(--bs-navbar-brand-padding-y);margin-right:var(--bs-navbar-brand-margin-end);font-size:var(--bs-navbar-brand-font-size);color:var(--bs-navbar-brand-color);white-space:nowrap}.navbar-nav{--bs-nav-link-padding-x:0;--bs-nav-link-padding-y:0.7rem;--bs-nav-link-color:var(--bs-navbar-color);--bs-nav-link-hover-color:var(--bs-navbar-hover-color);--bs-nav-link-disabled-color:var(--bs-navbar-disabled-color);display:flex;flex-direction:column;padding-left:0;margin-bottom:0;list-style:none}.navbar-collapse{flex-basis:100%;flex-grow:1;align-items:center}.navbar-toggler{padding:var(--bs-navbar-toggler-padding-y) var(--bs-navbar-toggler-padding-x);font-size:var(--bs-navbar-toggler-font-size);line-height:1;color:var(--bs-navbar-color);background-color:transparent;border:var(--bs-border-width) solid var(--bs-navbar-toggler-border-color);border-radius:var(--bs-navbar-toggler-border-radius)}@media (min-width:576px){.navbar-expand-sm{flex-wrap:nowrap;justify-content:flex-start}.navbar-expand-sm .navbar-nav{flex-direction:row}.navbar-expand-sm .navbar-nav .nav-link{padding-right:var(--bs-navbar-nav-link-padding-x);padding-left:var(--bs-navbar-nav-link-padding-x)}.navbar-expand-sm .navbar-collapse{display:flex!important;flex-basis:auto}.navbar-expand-sm .navbar-toggler{display:none}}body:before{display:none}.navbar-dark{--bs-navbar-color:#324a98;--bs-navbar-hover-color:#4d4d4f;--bs-navbar-disabled-color:rgba(255, 255, 255, 0.25);--bs-navbar-active-color:#324a98;--bs-navbar-brand-color:#324a98;--bs-navbar-brand-hover-color:#324a98;--bs-navbar-toggler-border-color:transparent;--bs-navbar-toggler-icon-bg:none}.card{--bs-card-spacer-y:1rem;--bs-card-spacer-x:1rem;--bs-card-title-spacer-y:0.5rem;--bs-card-border-width:1px;--bs-card-border-color:var(--bs-border-color-translucent);--bs-card-border-radius:0.375rem;--bs-card-inner-border-radius:calc(0.375rem - 1px);--bs-card-cap-padding-y:0.5rem;--bs-card-cap-padding-x:1rem;--bs-card-cap-bg:rgba(0, 0, 0, 0.03);--bs-card-bg:#f8f9fa;--bs-card-img-overlay-padding:1rem;--bs-card-group-margin:0.75rem;position:relative;display:flex;flex-direction:column;min-width:0;height:var(--bs-card-height);word-wrap:break-word;background-color:var(--bs-card-bg);background-clip:border-box;border:var(--bs-card-border-width) solid var(--bs-card-border-color);border-radius:var(--bs-card-border-radius);box-shadow:var(--bs-card-box-shadow)}.card-body{flex:1 1 auto;padding:var(--bs-card-spacer-y) var(--bs-card-spacer-x);color:var(--bs-card-color)}.breadcrumb{display:flex;list-style:none;--bs-breadcrumb-padding-x:0;--bs-breadcrumb-padding-y:0.5rem;--bs-breadcrumb-margin-bottom:0;--bs-breadcrumb-font-size:0.75rem;--bs-breadcrumb-bg:transparent;--bs-breadcrumb-divider-color:#6c757d;--bs-breadcrumb-item-padding-x:0.5rem;--bs-breadcrumb-item-active-color:#6c757d;flex-wrap:wrap;padding:var(--bs-breadcrumb-padding-y) var(--bs-breadcrumb-padding-x);margin-bottom:var(--bs-breadcrumb-margin-bottom);font-size:var(--bs-breadcrumb-font-size);background-color:var(--bs-breadcrumb-bg);border-radius:var(--bs-breadcrumb-border-radius)}.breadcrumb-item+.breadcrumb-item{padding-left:var(--bs-breadcrumb-item-padding-x)}.breadcrumb-item+.breadcrumb-item::before{float:left;padding-right:var(--bs-breadcrumb-item-padding-x);color:var(--bs-breadcrumb-divider-color);content:var(--bs-breadcrumb-divider, "|")}.breadcrumb-item.active{color:var(--bs-breadcrumb-item-active-color)}.alert{--bs-alert-bg:transparent;--bs-alert-padding-x:1rem;--bs-alert-padding-y:1rem;--bs-alert-margin-bottom:1rem;--bs-alert-color:inherit;--bs-alert-border-color:transparent;--bs-alert-border:1px solid var(--bs-alert-border-color);--bs-alert-border-radius:0.375rem;position:relative;padding:var(--bs-alert-padding-y) var(--bs-alert-padding-x);margin-bottom:var(--bs-alert-margin-bottom);color:var(--bs-alert-color);background-color:var(--bs-alert-bg);border:var(--bs-alert-border);border-radius:var(--bs-alert-border-radius)}.alert-heading{color:inherit}.alert-link{font-weight:700}.alert-dismissible{padding-right:3rem}.alert-dismissible .btn-close{position:absolute;top:0;right:0;z-index:2;padding:1.25rem 1rem}.alert-primary,.alert-secondary{background-image:var(--bs-gradient)}.alert-primary{--bs-alert-color:rgb(30, 44.4, 91.2);--bs-alert-bg:rgb(214, 218.8, 234.4);--bs-alert-border-color:rgb(193.5, 200.7, 224.1)}.alert-primary .alert-link{color:#182449}.alert-secondary{--bs-alert-color:rgb(64.8, 70.2, 75);--bs-alert-bg:rgb(225.6, 227.4, 229);--bs-alert-border-color:rgb(210.9, 213.6, 216)}.alert-secondary .alert-link{color:#34383c}.alert-native,.alert-success,.alert-validation{--bs-alert-color:rgb(15, 81, 50.4);--bs-alert-bg:rgb(209, 231, 220.8);--bs-alert-border-color:rgb(186, 219, 203.7);background-image:var(--bs-gradient)}.alert-native .alert-link,.alert-success .alert-link,.alert-validation .alert-link{color:#0c4128}.alert-info,.alert-warning{background-image:var(--bs-gradient)}.alert-info{--bs-alert-color:rgb(5.2, 80.8, 96);--bs-alert-bg:rgb(206.6, 244.4, 252);--bs-alert-border-color:rgb(182.4, 239.1, 250.5)}.alert-info .alert-link{color:#04414d}.alert-warning{--bs-alert-color:rgb(102, 77.2, 2.8);--bs-alert-bg:rgb(255, 242.6, 205.4);--bs-alert-border-color:rgb(255, 236.4, 180.6)}.alert-warning .alert-link{color:#523e02}.alert-danger,.alert-error{--bs-alert-color:#8a0000;--bs-alert-bg:#facccc;--bs-alert-border-color:rgb(247.5, 178.5, 178.5);background-image:var(--bs-gradient)}.alert-danger .alert-link,.alert-error .alert-link{color:#6e0000}.alert-light{--bs-alert-color:rgb(99.2, 99.6, 100);--bs-alert-bg:rgb(253.6, 253.8, 254);--bs-alert-border-color:rgb(252.9, 253.2, 253.5);background-image:var(--bs-gradient)}.alert-light .alert-link{color:#4f5050}.alert-cleanup,.alert-dark{--bs-alert-color:rgb(19.8, 22.2, 24.6);--bs-alert-bg:rgb(210.6, 211.4, 212.2);--bs-alert-border-color:rgb(188.4, 189.6, 190.8);background-image:var(--bs-gradient)}.alert-cleanup .alert-link,.alert-dark .alert-link{color:#101214}.alert-inverse{--bs-alert-color:#666666;--bs-alert-bg:white;--bs-alert-border-color:white}.alert-inverse .alert-link{color:#525252}.alert-inverse,.alert-navbar,.alert-navitem{background-image:var(--bs-gradient)}.alert-navbar{--bs-alert-color:rgb(87.2, 88, 88.8);--bs-alert-bg:rgb(247.6, 248, 248.4);--bs-alert-border-color:rgb(243.9, 244.5, 245.1)}.alert-navbar .alert-link{color:#464647}.alert-navitem{--bs-alert-color:#666666;--bs-alert-bg:white;--bs-alert-border-color:white}.alert-navitem .alert-link{color:#525252}.alert-lightgray{--bs-alert-color:rgb(93.2, 94.4, 95.6);--bs-alert-bg:rgb(250.6, 251.2, 251.8);--bs-alert-border-color:rgb(248.4, 249.3, 250.2)}.alert-lightgray .alert-link{color:#4b4c4c}.alert-color-indigo,.alert-lightgray{background-image:var(--bs-gradient)}.alert-advertising,.alert-color-indigo{--bs-alert-color:rgb(61.2, 9.6, 145.2);--bs-alert-bg:rgb(224.4, 207.2, 252.4);--bs-alert-border-color:rgb(209.1, 183.3, 251.1)}.alert-color-indigo .alert-link{color:#310874}.alert-color-cyan{--bs-alert-color:rgb(5.2, 80.8, 96);--bs-alert-bg:rgb(206.6, 244.4, 252);--bs-alert-border-color:rgb(182.4, 239.1, 250.5);background-image:var(--bs-gradient)}.alert-color-cyan .alert-link{color:#04414d}.alert-color-blue,.alert-criticalcss{--bs-alert-color:rgb(7.8, 66, 151.8);--bs-alert-bg:rgb(206.6, 226, 254.6);--bs-alert-border-color:rgb(182.4, 211.5, 254.4);background-image:var(--bs-gradient)}.alert-color-blue .alert-link,.alert-criticalcss .alert-link{color:#063579}.alert-color-orange{background-image:var(--bs-gradient)}.alert-cache,.alert-color-orange{--bs-alert-color:rgb(151.8, 75.6, 12);--bs-alert-bg:rgb(254.6, 229.2, 208);--bs-alert-border-color:rgb(254.4, 216.3, 184.5)}.alert-color-orange .alert-link{color:#793c0a}.alert-color-red{--bs-alert-color:rgb(132, 31.8, 41.4);--bs-alert-bg:rgb(248, 214.6, 217.8);--bs-alert-border-color:rgb(244.5, 194.4, 199.2);background-image:var(--bs-gradient)}.alert-color-red .alert-link{color:#6a1921}.alert-cdnjs,.alert-color-yellow{--bs-alert-color:rgb(102, 77.2, 2.8);--bs-alert-bg:rgb(255, 242.6, 205.4);--bs-alert-border-color:rgb(255, 236.4, 180.6)}.alert-cdnjs .alert-link,.alert-color-yellow .alert-link{color:#523e02}.alert-cdnjs,.alert-color-teal,.alert-color-yellow{background-image:var(--bs-gradient)}.alert-color-teal,.alert-topic{--bs-alert-color:rgb(19.2, 120.6, 90.6);--bs-alert-bg:rgb(210.4, 244.2, 234.2);--bs-alert-border-color:rgb(188.1, 238.8, 223.8)}.alert-color-teal .alert-link{color:#0f6048}.alert-color-green{--bs-alert-color:rgb(15, 81, 50.4);--bs-alert-bg:rgb(209, 231, 220.8);--bs-alert-border-color:rgb(186, 219, 203.7);background-image:var(--bs-gradient)}.alert-color-green .alert-link{color:#0c4128}.alert-cloudinary,.alert-color-pink{--bs-alert-color:rgb(128.4, 30.6, 79.2);--bs-alert-bg:rgb(246.8, 214.2, 230.4);--bs-alert-border-color:rgb(242.7, 193.8, 218.1);background-image:var(--bs-gradient)}.alert-cloudinary .alert-link,.alert-color-pink .alert-link{color:#67183f}.alert-color-black{--bs-alert-color:black;--bs-alert-bg:#cccccc;--bs-alert-border-color:rgb(178.5, 178.5, 178.5);background-image:var(--bs-gradient)}.alert-color-black .alert-link{color:#000}.alert-color-white{--bs-alert-color:#666666;--bs-alert-bg:white;--bs-alert-border-color:white;background-image:var(--bs-gradient)}.alert-color-white .alert-link{color:#525252}.alert-color-gray{--bs-alert-color:rgb(64.8, 70.2, 75);--bs-alert-bg:rgb(225.6, 227.4, 229);--bs-alert-border-color:rgb(210.9, 213.6, 216);background-image:var(--bs-gradient)}.alert-color-gray .alert-link{color:#34383c}.alert-color-gray-dark{--bs-alert-color:rgb(31.2, 34.8, 38.4);--bs-alert-bg:rgb(214.4, 215.6, 216.8);--bs-alert-border-color:rgb(194.1, 195.9, 197.7);background-image:var(--bs-gradient)}.alert-color-gray-dark .alert-link{color:#191c1f}.alert-cache{--bs-alert-color:rgb(61.2, 9.6, 145.2);--bs-alert-bg:rgb(224.4, 207.2, 252.4);--bs-alert-border-color:rgb(209.1, 183.3, 251.1);background-image:var(--bs-gradient)}.alert-cache .alert-link{color:#310874}.alert-notice{--bs-alert-color:rgb(5.2, 80.8, 96);--bs-alert-bg:rgb(206.6, 244.4, 252);--bs-alert-border-color:rgb(182.4, 239.1, 250.5)}.alert-notice .alert-link{color:#04414d}.alert-advertising,.alert-notice,.alert-topic{background-image:var(--bs-gradient)}.alert-topic{--bs-alert-color:rgb(113.4, 34.2, 10.2);--bs-alert-bg:rgb(241.8, 215.4, 207.4);--bs-alert-border-color:rgb(235.2, 195.6, 183.6)}.alert-topic .alert-link{color:#5b1b08}.alert-advertising{--bs-alert-color:rgb(102, 77.2, 2.8);--bs-alert-bg:rgb(255, 242.6, 205.4);--bs-alert-border-color:rgb(255, 236.4, 180.6)}.alert-advertising .alert-link{color:#523e02}.list-group{--bs-list-group-color:#212529;--bs-list-group-bg:#fff;--bs-list-group-border-color:rgba(0, 0, 0, 0.125);--bs-list-group-border-width:1px;--bs-list-group-border-radius:0.375rem;--bs-list-group-item-padding-x:1rem;--bs-list-group-item-padding-y:0.5rem;--bs-list-group-action-color:#495057;--bs-list-group-action-hover-color:#495057;--bs-list-group-action-hover-bg:#f8f9fa;--bs-list-group-action-active-color:#212529;--bs-list-group-action-active-bg:#e9ecef;--bs-list-group-disabled-color:#6c757d;--bs-list-group-disabled-bg:#fff;--bs-list-group-active-color:#fff;--bs-list-group-active-bg:#bd3911;--bs-list-group-active-border-color:#bd3911;display:flex;flex-direction:column;padding-left:0;margin-bottom:0;border-radius:var(--bs-list-group-border-radius)}.list-group-item{position:relative;display:block;padding:var(--bs-list-group-item-padding-y) var(--bs-list-group-item-padding-x);color:var(--bs-list-group-color);background-color:var(--bs-list-group-bg);border:var(--bs-list-group-border-width) solid var(--bs-list-group-border-color)}.list-group-item:first-child{border-top-left-radius:inherit;border-top-right-radius:inherit}.list-group-item:last-child{border-bottom-right-radius:inherit;border-bottom-left-radius:inherit}.list-group-item+.list-group-item{border-top-width:0}.btn-close{box-sizing:content-box;width:1em;height:1em;padding:.25em;color:#000;background:url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23000'%3e%3cpath d='M.293.293a1 1 0 0 1 1.414 0L8 6.586 14.293.293a1 1 0 1 1 1.414 1.414L9.414 8l6.293 6.293a1 1 0 0 1-1.414 1.414L8 9.414l-6.293 6.293a1 1 0 0 1-1.414-1.414L6.586 8 .293 1.707a1 1 0 0 1 0-1.414z'/%3e%3c/svg%3e") center/1em auto no-repeat;border:0;border-radius:.375rem;opacity:.5}.modal{--bs-modal-zindex:1055;--bs-modal-width:500px;--bs-modal-padding:1rem;--bs-modal-margin:0.5rem;--bs-modal-bg:#fff;--bs-modal-border-color:var(--bs-border-color-translucent);--bs-modal-border-width:1px;--bs-modal-border-radius:0.5rem;--bs-modal-box-shadow:0 0.125rem 0.25rem rgba(0, 0, 0, 0.075);--bs-modal-inner-border-radius:calc(0.5rem - 1px);--bs-modal-header-padding-x:1rem;--bs-modal-header-padding-y:1rem;--bs-modal-header-padding:1rem 1rem;--bs-modal-header-border-color:var(--bs-border-color);--bs-modal-header-border-width:1px;--bs-modal-title-line-height:1.5;--bs-modal-footer-gap:0.5rem;--bs-modal-footer-border-color:var(--bs-border-color);--bs-modal-footer-border-width:1px;position:fixed;top:0;left:0;z-index:var(--bs-modal-zindex);display:none;width:100%;height:100%;overflow-x:hidden;overflow-y:auto;outline:0}.modal-dialog{position:relative;width:auto;margin:var(--bs-modal-margin)}.modal.fade .modal-dialog{transform:translate(0,-50px)}.modal-content{position:relative;display:flex;flex-direction:column;width:100%;color:var(--bs-modal-color);background-color:var(--bs-modal-bg);background-clip:padding-box;border:var(--bs-modal-border-width) solid var(--bs-modal-border-color);border-radius:var(--bs-modal-border-radius);box-shadow:var(--bs-modal-box-shadow);outline:0}.modal-header{display:flex;flex-shrink:0;align-items:center;justify-content:space-between;padding:var(--bs-modal-header-padding);border-bottom:var(--bs-modal-header-border-width) solid var(--bs-modal-header-border-color);border-top-left-radius:var(--bs-modal-inner-border-radius);border-top-right-radius:var(--bs-modal-inner-border-radius)}.modal-title{margin-bottom:0;line-height:var(--bs-modal-title-line-height)}.modal-body{position:relative;flex:1 1 auto;padding:var(--bs-modal-padding)}@media (min-width:576px){.modal{--bs-modal-margin:1.75rem;--bs-modal-box-shadow:0 0.5rem 1rem rgba(0, 0, 0, 0.15)}.modal-dialog{max-width:var(--bs-modal-width);margin-right:auto;margin-left:auto}.modal-sm{--bs-modal-width:300px}}.offcanvas{--bs-offcanvas-zindex:1045;--bs-offcanvas-width:400px;--bs-offcanvas-height:30vh;--bs-offcanvas-padding-x:1rem;--bs-offcanvas-padding-y:1rem;--bs-offcanvas-bg:#fff;--bs-offcanvas-border-width:1px;--bs-offcanvas-border-color:var(--bs-border-color-translucent);--bs-offcanvas-box-shadow:0 0.125rem 0.25rem rgba(0, 0, 0, 0.075);position:fixed;bottom:0;z-index:var(--bs-offcanvas-zindex);display:flex;flex-direction:column;max-width:100%;color:var(--bs-offcanvas-color);visibility:hidden;background-color:var(--bs-offcanvas-bg);background-clip:padding-box;outline:0;box-shadow:var(--bs-offcanvas-box-shadow)}.offcanvas.offcanvas-start{top:0;left:0;width:var(--bs-offcanvas-width);border-right:var(--bs-offcanvas-border-width) solid 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itemprop="author" itemscope itemtype="https://schema.org/Person"> <meta itemprop="name" content="Tech Briefs"> </span><a id="startOfPage"></a> <h4>Drug-Loaded 3D Printed Films</h4> <figure title=""><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1723390717/sites/mdb/articles/2024/features/MDB-0824-p4-fig1.png' class=' w-100 cld-responsive' alt='' /></figure> <p>Drug-loaded 3D-printed films could change cancer treatments forever as world first research from the University of South Australia shows the new films kill liver cancer cells by more than 80 percent, with less systematic toxicities of chemotherapy. Created from gels, the biodegradable 3D printed films are loaded with tailored doses of anti-cancer drugs 5-fluorouracil (5FU) and cisplatin (Cis) and placed at the exact surgical site where a cancer has been removed, localizing drugs to the affected area while limiting the undesirable side effects of traditional chemotherapy.</p> <p><strong>Visit <a href="/component/content/article/51071" target="_blank" rel="noopener">Here</a></strong></p> <hr /> <h4>Discovery Boosts Potential of New Cancer-Fighting Drugs</h4> <figure title=""><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1723390717/sites/mdb/articles/2024/features/MDB-0824-p4-fig2.png' class=' w-100 cld-responsive' alt='' /></figure> <p>Scientists at Scripps Research have uncovered a critical feature that a promising new class of cancer drugs, known as CELMoDs, needs to be effective. CELMoDs are designed to attack cancer in a novel way, by binding to a regulatory protein called cereblon, which then triggers the degradation of key cancer-driving proteins.</p> <p><strong>Visit <a href="/component/content/article/51072" target="_blank" rel="noopener">Here</a></strong></p> <hr /> <h4>The Bridge Recombination Mechanism — Next Generation Genome Design</h4> <figure title=""><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1723390718/sites/mdb/articles/2024/features/MDB-0824-p4-fig3.png' class=' w-100 cld-responsive' alt='' /></figure><div class="ad-position g-0 row mb-3 "> <div class="col-12 align-content-center mx-auto"> <script tb-donotmove>window.ntb_google_ad_manager_items=window.ntb_google_ad_manager_items||[];ntb_google_ad_manager_items.push({display_sizes:['xs','sm'],slot_ad_unit:'medicaldesignbriefs.com_450x450_300x300',slot_code:'21835072403',slot:'/21835072403/medicaldesignbriefs.com_450x450_300x300',slot_ad_sizes:['fluid',[450,450],[300,300]],div_id:'GAM_pos_22_modid_421',target_pos:'22',size_mapping:[],slot_ad_empty:'default'});</script> <div id='GAM_pos_22_modid_421' class=""></div></div></div><p>Researchers have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way. Going far beyond programmable genetic scissors like CRISPR, the bridge recombinase mechanism enables scientists to specify not only the target DNA to be modified, but also the donor material to be recognized, so they can insert new, functional genetic material, cut out faulty DNA, or invert any two sequences of interest.</p> <p><strong>Visit <a href="/component/content/article/51073" target="_blank" rel="noopener">Here</a></strong></p> <hr /> <h4>Immunotherapy: Drug Harnesses Immune System Against Cancer</h4> <figure title=""><img src='data:image/svg+xml;base64,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' data-src='https://res.cloudinary.com/tbmg/c_scale,w_auto,f_auto,q_auto/v1723390718/sites/mdb/articles/2024/features/MDB-0824-p4-fig4.png' class=' w-100 cld-responsive' alt='' /></figure> <p>Certain types of immune cells called regulatory T-cells, while vital for a balanced immune system, can hinder the cancer-killing process. Targeting these cells without affecting other immune cells in the past has been difficult. A new drug can stop regulatory T-cells from working while leaving other immune cells intact to fight the cancer cells. Watch this drug in action in this short animation.</p> <p><strong>Visit <a href="/component/content/article/51074" target="_blank" rel="noopener">Here</a></strong></p> <hr> <div class="ntb_tagsbot"> <div class="taglist"> <strong class="sans-serif text-small">Topics:</strong><br> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/medical/diagnostics/mdb/*?start=0"> <i class="fa-duotone fa-book-medical"></i> Diagnostics</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/markets/drug_delivery/mdb/*?start=0"> <i class="fa-duotone fa-people-group"></i> Drug Delivery</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" href="/component/ntb_tags/topic/medical/drug_delivery/mdb/*?start=0"> <i class="fa-duotone fa-book-medical"></i> Drug Delivery</a> <a class="badge bg-primary link-white fw-light sans-serif text-small fst-normal" 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