低分子医薬品の開発・製造サービス - パセオンファーマサービス（ Patheon pharma services）

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class="h1 d-inline-block " style="color:;"> 低分子医薬品の開発・製造サービス </h1> <h2 class="h2 d-block" style="color:;"> スピードと敏捷性で、お客様の低分子医薬品の開発を前進させます </h2> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> </div> </div> </div> <style type="text/css"> .cmp-hero #hero h1 span::before { background-color: ; } #hero { min-height: 300px; } </style> <style type="text/css"> #hero { background-image: url('/content/dam/patheon/global/hero-images/molecule_small.png'); background-position: center center; } </style> </div> <div class="cmp-well aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--newline aem-GridColumn aem-GridColumn--default--12"> <div class="well " style="background-position-x: center;background-position-y: top;background-image: url('/content/dam/patheon/global/site-images/small-molecule/Small Molecule.png');" id="Small-Molecule-Well-1"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 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<p>低分子医薬品プロジェクトは、溶解性や生物学的利用能の改善、厳しい規制環境への適応、高品質な原料の安定供給など、多くの要件を満たす必要があります。プロジェクトの規模に関わらず、成功には柔軟な原薬、製剤、治験サプライチェーンソリューションを提供できるパートナーが不可欠です。スケジュールと予算を守りながらマイルストーンを達成し、サプライチェーンの継続性を保証する能力が求められます。信頼性の高いCDMOに低分子医薬品の開発と製造を委ねることで、一連のサービスを統合し、プロジェクトの引き継ぎを簡素化し、ミスを減らし、コストのかかる遅れを避け、開発期間を短縮し、新薬を迅速に市場に投入することができます。パセオンは、23カ国に60以上の拠点を持つ統合グローバルネットワークと、確かな専門知識を持つエキスパートチームを通じて、新薬の上市を強力に支援いたします。また、Patheon Quadrant 2™予測モデリングプラットフォームを使用して、溶解性と生物学的利用能の課題を解決します。</p> </div> </div> <div class="custom-html-cmp aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--default--12"> <style type="text/css"> @media (max-width: 767px) { #Small-Molecule-Well-1 { background-image:none !important; } } </style> </div> </div> </div> </div> <style type="text/css"> #Small-Molecule-Well-1 { border-radius: 0px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " id="well-515620411"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 "> <div class="text aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--12"> <div id="text-d96b9b4cf2" class="cmp-text list-style-bullets"> <h2>臨床入りから上市までサポートする共同作業</h2> <h3><span class="font-weight-normal">スピード、品質、効率性を最大限に高めます</span></h3> <p>低分子医薬品の開発には、合成方法、試験用原薬や製剤の開発、最適な処方、スケールアップ手法、サプライチェーンへの影響、迅速なIND申請のためのデータ、問題発生時の対応など、多くの考慮事項があります。パセオンは、エンドツーエンドのソリューション、深い専門知識、業界をリードする技術を活用して、最初から正しい製品設計を実現するRight-The-First-Timeサービスを通じて、低分子開発を強力に支援いたします。</p> </div> </div> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-918a1d2079" class="cmp-text list-style-bullets"> <h2>幅広いプランニング・実行力により、当て推量を排除</h2> </div> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner p-2 " id="container-1807928211"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-944c2741d4" class="cmp-text list-style-check"> <ul> <li style="color: rgb(38,34,98);"><b>アイデアや分子に潜む問題点を評価 </b></li><li style="color: rgb(38,34,98);"><b>効率性の高い開発計画の構築</b></li><li style="color: rgb(38,34,98);"><b>最適な処方開発</b></li><li style="color: rgb(38,34,98);"><b>臨床試験用原薬の製造・供給 </b></li><li style="color: rgb(38,34,98);"><b>包装・流通手法の開発 </b></li><li style="color: rgb(38,34,98);"><b>臨床研究の実施</b></li><li style="color: rgb(38,34,98);"><b>規制当局への申請・承認取得サポート</b></li><li style="color: rgb(38,34,98);"><b>製剤の製造・供給 </b></li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-1807928211{ background-image: url(''); background-color: #F7F7F7; background-size: cover; background-position: center; min-height: px; } #container-1807928211 { border-radius: px; } </style> </div> </div> </div> </div> <style type="text/css"> #well-515620411 { border-radius: 0px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " style="background-position-x: center;background-position-y: center;background-image: url('/content/dam/patheon/global/site-images/softgels/Made In Background Blue.png');" id="well-302321631"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-50f3b97385" class="cmp-text list-style-bullets"> <h2><span style="color: rgb(255,255,255);">なぜ低分子医薬品は、バイオ医薬品よりも製造が難しいのでしょうか？</span></h2> <p><span style="color: rgb(255,255,255);">バイオ医薬品は通常、注射によって患者の体内に直接投与され、迅速に作用します。一方で、低分子医薬品は、消化器系や肝臓といった体の防御システムを通過する必要があり、これらの器官は有害な合成化合物から体を守る役割を果たしています。低分子医薬品は溶解してから体内に吸収されるため、その溶解性や吸収速度を適切に調整することが重要です。また、安全で一貫した投与量を患者に提供するためには、低分子の固体特性を考慮した製造プロセスが必要です。</span></p> </div> </div> </div> </div> </div> <style type="text/css"> #well-302321631 { border-radius: 0px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " id="well-1913006111"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--large--12 "> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--large--6 aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"> <div class="cmp-container-inner me-xl-3 me-lg-3 me-md-3 equalizeHeights h-100" id="container-1007128913"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--12 aem-Grid--default--4 aem-Grid--xsmall--4 aem-Grid--large--6 "> <div class="cmp-image-card flex-cmp mb-3 aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 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class="cmp-text list-style-bullets"> <h3>原薬（API）</h3> <p>原薬と製剤のシームレスな開発・製造により、さまざまなメリットを提供いたします。</p> <ul> <li><p>初期開発ソリューション</p> </li> <li><p>プロセス開発、バリデーション、スケールアップ、技術移管</p> </li> <li><p>第二世代プロセス開発</p> </li> <li><p>分析サービス</p> </li> <li><p>溶解性改善ソリューション </p> </li> </ul> </div> </div> <div class="cmp-button aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--large--6 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--4"> <div id="button-1559083417" class="btn-wrapper"> <a class=" btn btn-style-imageCardButton icon-placement-right full-width " data-icon="" href="https://www.patheon.jp/our-capabilities/small-molecule/api-development" role="button" target="_self"> メリットを見る </a> </div> <style> #button-1559083417 .btn-style-quickLink { 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aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--large--6 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--4"><div id="image_card-1896186739" class="card h-100 innerPadding"> <div class="card-image" style="background:url('/content/dam/patheon/global/site-images/small-molecule/Oral Solid Dose OSD.png'); background-color:#ffffff;"> </div> <div class="card-body d-flex" style="background-color:#ffffff;"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--12 aem-Grid--default--4 aem-Grid--xsmall--12 aem-Grid--large--6 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--large--6 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--4"> <div id="text-12e2dfc84a" class="cmp-text list-style-bullets"> <h3>経口固形製剤（OSD）</h3> <p>柔軟性の高い経口固形製剤（OSD）商用生産ソリューションにより事業とサプライチェーンの継続性を確保いたします。</p> <ul> <li><p>処方開発</p> </li> <li><p>プロセスの開発・最適化</p> </li> <li><p>さまざまな剤形</p> </li> <li><p>技術移管 </p> </li> </ul> </div> </div> <div class="cmp-button aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--large--6 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--4"> <div id="button-1067399209" class="btn-wrapper"> <a class=" btn btn-style-imageCardButton icon-placement-right full-width " data-icon="" href="https://www.patheon.jp/our-capabilities/small-molecule/oral-solid-dose" role="button" target="_self"> 方法を見る </a> </div> <style> #button-1067399209 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aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"><div id="image_card-1311177265" class="card h-100 innerPadding"> <div class="card-image" style="background:url('/content/dam/patheon/global/site-images/steriles/Vials.png'); background-color:#ffffff;"> </div> <div class="card-body d-flex" style="background-color:#ffffff;"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--12 aem-Grid--default--4 aem-Grid--xsmall--12 aem-Grid--large--6 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--4"> <div id="text-13ac109179" class="cmp-text list-style-bullets"> <h3>無菌製剤</h3> <p>製品ライフサイクル全体のさまざまな複雑な課題を解決いたします。 </p> <ul> <li>処方開発</li> <li>プロセス開発、バリデーション、スケールアップ </li> <li>薬物送達・無菌充填（Fill Finish）サービス</li> <li>コールドチェーン（低温物流）サービス</li> </ul> </div> </div> <div class="cmp-button aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"> <div id="button-207881259" class="btn-wrapper"> <a class=" btn btn-style-imageCardButton icon-placement-right full-width " data-icon="" href="https://www.patheon.jp/our-capabilities/small-molecule/softgels" role="button" target="_self"> 続きを読む </a> </div> <style> #button-207881259 .btn-style-quickLink { border-left: 6px solid #1E8AE7; } #button-207881259 { padding-right:0px; padding-left:0px; } </style> </div> </div> </div> </div></div> </div> </div> <style type="text/css"> #container-132500415{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-132500415 { border-radius: px; } </style> </div> <div class="cmp-image-card flex-cmp mb-3 aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"><div id="image_card-1559242095" class="card h-100 innerPadding"> <div class="card-image" style="background:url('/content/dam/patheon/global/site-images/small-molecule/Softgels.png'); background-color:#ffffff;"> </div> <div class="card-body d-flex" style="background-color:#ffffff;"> <div class="aem-Grid aem-Grid--4 aem-Grid--small--12 aem-Grid--default--4 aem-Grid--xsmall--12 aem-Grid--large--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--4"> <div id="text-1b5ab9e0d0" class="cmp-text list-style-bullets"> <h3>ソフトカプセル</h3> <p>初期開発から商用生産まで、医療用医薬品・OTC医薬品のソフトカプセル処方はお任せください。</p> <ul> <li>バイオアベイラビリティ向上</li> <li>麻薬取締局（DEA）規制薬物</li> <li>乱用防止製剤 </li> </ul> </div> </div> <div class="cmp-button aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--offset--large--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--large--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"> <div id="button-840097845" class="btn-wrapper"> <a class=" btn btn-style-imageCardButton 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