Cancer - BioSpace

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><picture> <source type="image/webp" width="1440" height="810" srcset="https://static.biospace.com/dims4/default/5787a01/2147483647/strip/true/crop/622x350+1+0/resize/568x320!/format/webp/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg 568w,https://static.biospace.com/dims4/default/56ac1cf/2147483647/strip/true/crop/622x350+1+0/resize/768x432!/format/webp/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg 768w,https://static.biospace.com/dims4/default/184755f/2147483647/strip/true/crop/622x350+1+0/resize/1024x576!/format/webp/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg 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568w,https://static.biospace.com/dims4/default/25d3dfd/2147483647/strip/true/crop/622x350+1+0/resize/768x432!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg 768w,https://static.biospace.com/dims4/default/06320aa/2147483647/strip/true/crop/622x350+1+0/resize/1024x576!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg 1024w,https://static.biospace.com/dims4/default/59ec57a/2147483647/strip/true/crop/622x350+1+0/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg 1440w" width="1440" height="810" src="https://static.biospace.com/dims4/default/59ec57a/2147483647/strip/true/crop/622x350+1+0/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F9D79FB12-1A9D-42D1-ACE3-4C6238FA2844.jpg" loading="lazy" > </picture> </a></div> <div class="PagePromo-content"> <div class="PagePromo-category"> <a class="Link" href="https://www.biospace.com/mergers-acquisitions">Mergers & acquisitions</a> </div> <div class="PagePromo-title"> <a class="Link" href="https://www.biospace.com/business/roche-buys-poseida-for-up-to-1-5b-leaning-into-off-the-shelf-car-t">Roche Buys Poseida for up to $1.5B, Leaning Into Off-the-Shelf CAR T</a> </div> <div class="PagePromo-description"> The acquisition announcement came alongside the reveal of a Phase III failure for Roche’s TIGIT asset tiragolumab, which when combined with Tecentriq did not significantly boost overall survival in non-small cell lung cancer. </div> <div class="PagePromo-byline"><div class="PagePromo-date">November 26, 2024</div><span class="dot"> · </span><div class="PagePromo-readTime">3 min read</div><span class="dot"> · </span><div class="PagePromo-author"><a class="Link" href="https://www.biospace.com/tristan-manalac">Tristan Manalac</a></div></div> </div> </div> </div> <div class="PageList-items-item"> <div class="PagePromo" data-image-align-horizontal="right" data-mobile-alt-layout="true"> <div class="PagePromo-media"><a class="Link" aria-label="AstraZeneca’s Truqap Redeems Itself with Phase III Prostate Cancer Win" href="https://www.biospace.com/drug-development/astrazenecas-truqap-redeems-itself-with-phase-iii-prostate-cancer-win" ><picture> <source type="image/webp" width="1440" height="810" 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src="https://static.biospace.com/dims4/default/783aba8/2147483647/strip/true/crop/622x350+1+0/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F635BDC0A-97E8-4490-9EDD-36C93DB5A566.jpg" loading="lazy" > </picture> </a></div> <div class="PagePromo-content"> <div class="PagePromo-category"> <a class="Link" href="https://www.biospace.com/prostate-cancer">Prostate cancer</a> </div> <div class="PagePromo-title"> <a class="Link" href="https://www.biospace.com/drug-development/astrazenecas-truqap-redeems-itself-with-phase-iii-prostate-cancer-win">AstraZeneca’s Truqap Redeems Itself with Phase III Prostate Cancer Win</a> </div> <div class="PagePromo-description"> Truqap’s positive clinical data comes after it failed a late-stage study in metastatic triple-negative breast cancer. 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src="https://static.biospace.com/dims4/default/5233035/2147483647/strip/true/crop/788x443+0+0/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Ff3%2F6d%2Feedaf1ae4145ac73296dde6f4a59%2Fadc.jpg" loading="lazy" > </picture> </a></div> <div class="PagePromo-content"> <div class="PagePromo-category"> <a class="Link" href="https://www.biospace.com/antibody-drug-conjugate-adc">Antibody-drug conjugate</a> </div> <div class="PagePromo-title"> <a class="Link" href="https://www.biospace.com/drug-development/next-gen-adcs-driving-renaissance-in-already-hot-oncology-drug-class">Next-Gen ADCs Driving ‘Renaissance’ in Already Hot Oncology Drug Class</a> </div> <div class="PagePromo-description"> ADC Therapeutics, Sutro Biopharma and Zai Lab are among those developing antibody-drug conjugates to address payload and toxicity challenges of current ADCs—and rapidly grow the multibillion-dollar market. </div> <div class="PagePromo-byline"><div 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Digital drawing." srcset="https://static.biospace.com/dims4/default/ed57bd6/2147483647/strip/true/crop/1296x729+0+41/resize/568x320!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2F81%2Fc6%2F593f71e549d3831303d4a03b90ab%2Fistock-1441922329.jpg 568w,https://static.biospace.com/dims4/default/8fe3d8d/2147483647/strip/true/crop/1296x729+0+41/resize/768x432!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2F81%2Fc6%2F593f71e549d3831303d4a03b90ab%2Fistock-1441922329.jpg 768w,https://static.biospace.com/dims4/default/995d468/2147483647/strip/true/crop/1296x729+0+41/resize/1024x576!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2F81%2Fc6%2F593f71e549d3831303d4a03b90ab%2Fistock-1441922329.jpg 1024w,https://static.biospace.com/dims4/default/d5104f1/2147483647/strip/true/crop/1296x729+0+41/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2F81%2Fc6%2F593f71e549d3831303d4a03b90ab%2Fistock-1441922329.jpg 1440w" width="1440" height="810" src="https://static.biospace.com/dims4/default/d5104f1/2147483647/strip/true/crop/1296x729+0+41/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2F81%2Fc6%2F593f71e549d3831303d4a03b90ab%2Fistock-1441922329.jpg" loading="lazy" > </picture> </a></div> <div class="PagePromo-content"> <div class="PagePromo-category"> <a class="Link" href="https://www.biospace.com/clinical-research">Clinical research</a> </div> <div class="PagePromo-title"> <a class="Link" href="https://www.biospace.com/drug-development/mercks-subcutaneous-keytruda-meets-expectations-in-phase-iii">Merck’s Subcutaneous Keytruda Meets Expectations in Phase III</a> </div> <div class="PagePromo-description"> Analysts are split on whether the positive trial results will help Merck stem future Keytruda losses as the mega-blockbuster goes off patent in 2028. </div> <div class="PagePromo-byline"><div class="PagePromo-date">November 19, 2024</div><span class="dot"> · </span><div class="PagePromo-readTime">2 min read</div><span class="dot"> · </span><div class="PagePromo-author"><a class="Link" href="https://www.biospace.com/annalee-armstrong">Annalee Armstrong</a></div></div> </div> </div> </div> <div class="PageList-items-item"> <div class="PagePromo" data-image-align-horizontal="right" data-mobile-alt-layout="true"> <div class="PagePromo-media"><a class="Link" aria-label="Novartis Drops Up to $745M to Move Deeper Into Competitive Radiopharma Space" href="https://www.biospace.com/deals/novartis-drops-up-to-745m-to-move-deeper-into-competitive-radiopharma-space" ><picture> <source type="image/webp" width="1440" height="810" 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src="https://static.biospace.com/dims4/default/0f96bb7/2147483647/strip/true/crop/1024x576+0+282/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Fa1%2Fce%2Fed28103247f9acba9a8a0a737ffb%2Fistock-1384818368.jpg" loading="lazy" > </picture> </a></div> <div class="PagePromo-content"> <div class="PagePromo-category"> <a class="Link" href="https://www.biospace.com/radiopharmaceuticals">Radiopharma</a> </div> <div class="PagePromo-title"> <a class="Link" href="https://www.biospace.com/deals/novartis-drops-up-to-745m-to-move-deeper-into-competitive-radiopharma-space">Novartis Drops Up to $745M to Move Deeper Into Competitive Radiopharma Space</a> </div> <div class="PagePromo-description"> The deal has secured Novartis the chance to work with Ratio Therapeutics on a novel drug candidate that could fortify the Big Pharma against competition from would-be radiopharmaceutical rivals such as BMS and Lilly. </div> <div class="PagePromo-byline"><div class="PagePromo-date">November 18, 2024</div><span class="dot"> · </span><div class="PagePromo-readTime">2 min read</div><span class="dot"> · </span><div class="PagePromo-author"><a class="Link" href="https://www.biospace.com/nick-paul-taylor">Nick Paul Taylor</a></div></div> </div> </div> </div> <div class="PageList-items-item"> <div class="PagePromo" data-image-align-horizontal="right" data-mobile-alt-layout="true"> <div class="PagePromo-media"><a class="Link" aria-label="Merck Hops Onto PD-1/VEGF Train, Committing up to $3B Plus in LaNova Deal" href="https://www.biospace.com/business/merck-hops-onto-pd-1-vegf-train-committing-up-to-3b-plus-in-lanova-deal" ><picture> <source type="image/webp" width="1440" height="810" srcset="https://static.biospace.com/dims4/default/ce26056/2147483647/strip/true/crop/622x350+1+0/resize/568x320!/format/webp/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F6024CEFE-D547-4D15-904F-01E9BE0CBF9D.jpg 568w,https://static.biospace.com/dims4/default/fbe74f8/2147483647/strip/true/crop/622x350+1+0/resize/768x432!/format/webp/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F6024CEFE-D547-4D15-904F-01E9BE0CBF9D.jpg 768w,https://static.biospace.com/dims4/default/c938d1b/2147483647/strip/true/crop/622x350+1+0/resize/1024x576!/format/webp/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F6024CEFE-D547-4D15-904F-01E9BE0CBF9D.jpg 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Inc. is an American multinational pharmaceutical company" srcset="https://static.biospace.com/dims4/default/218d7cf/2147483647/strip/true/crop/622x350+1+0/resize/568x320!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F6024CEFE-D547-4D15-904F-01E9BE0CBF9D.jpg 568w,https://static.biospace.com/dims4/default/bd8b456/2147483647/strip/true/crop/622x350+1+0/resize/768x432!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F6024CEFE-D547-4D15-904F-01E9BE0CBF9D.jpg 768w,https://static.biospace.com/dims4/default/39b610f/2147483647/strip/true/crop/622x350+1+0/resize/1024x576!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2Flegacy%2FBioSpace-Assets%2F6024CEFE-D547-4D15-904F-01E9BE0CBF9D.jpg 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</div> <div class="PagePromo-description"> Despite recent enthusiasm around the PD-1/VEGF space, BMO Capital Markets analyst Evan Seigerman noted that Merck’s pact with LaNova Medicines is more “conservativism” on the pharma’s part than confirmatory of recent data in the drug class. </div> <div class="PagePromo-byline"><div class="PagePromo-date">November 14, 2024</div><span class="dot"> · </span><div class="PagePromo-readTime">2 min read</div><span class="dot"> · </span><div class="PagePromo-author"><a class="Link" href="https://www.biospace.com/tristan-manalac">Tristan Manalac</a></div></div> </div> </div> </div> <div class="PageList-items-item"> <div class="PagePromo" data-image-align-horizontal="right" data-mobile-alt-layout="true"> <div class="PagePromo-media"><a class="Link" aria-label="GSK Builds Case for Blenrep with Multiple Myeloma OS Data That Bests J&J’s Darzalex" 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src="https://static.biospace.com/dims4/default/fefce94/2147483647/strip/true/crop/622x350+0+0/resize/1440x810!/quality/90/?url=https%3A%2F%2Fk1-prod-biospace.s3.us-east-2.amazonaws.com%2Fbrightspot%2F8d%2Ff5%2Faa58f180409db2b4d3dce5ccf6c9%2Fgsk.jpeg" loading="lazy" > </picture> </a></div> <div class="PagePromo-content"> <div class="PagePromo-category"> <a class="Link" href="https://www.biospace.com/cancer">Cancer</a> </div> <div class="PagePromo-title"> <a class="Link" href="https://www.biospace.com/drug-development/gsk-builds-case-for-blenrep-with-multiple-myeloma-os-data-that-bests-j-js-darzalex">GSK Builds Case for Blenrep with Multiple Myeloma OS Data That Bests J&J’s Darzalex</a> </div> <div class="PagePromo-description"> GSK is carving out a niche for Blenrep in the second-line multiple myeloma setting, for which it projects multi-blockbuster potential for the antibody-drug conjugate. </div> <div class="PagePromo-byline"><div class="PagePromo-date">November 14, 2024</div><span 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