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Validation of Palliative Prognostic Index for Terminal Cancer Patients in Hospice Consultation Setting in Taiwan
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} </script> <script src="//translate.google.com/translate_a/element.js?cb=googleTranslateElementInit"></script> </ul> </div> </nav> <div class="container-fluid bg-grey"> <div class="container pt-3 pb-4"> <div class="white-container mt-4"> <h2 class="bg-hdr">Validation of Palliative Prognostic Index for Terminal Cancer Patients in Hospice Consultation Setting in Taiwan</h2> <p style="line-height: 200%; margin-top: 0cm; margin-right: 0cm; margin-bottom: 0pt; margin-left: 0cm; text-align: center;"><span lang="EN-US"><span style="font-family: Times New Roman; font-size: 20px;">Validation of Palliative Prognostic Index for Terminal Cancer Patients in Hospice Consultation Setting in Taiwan.</span></span></p> <p style="line-height: 200%; margin: 0cm 0cm 0pt;"> </p> <p style="line-height: 200%; margin: 0cm 0cm 0pt;"><span style="font-size: small;">Wei-Hong Cheng, M.D., Chen-Yi Kao, M.D., Po-Jung Su, M.D., Chia-Hsun Hsieh, M.D., Jen-Shi Chen, M.D., Hung-Ming Wang, M.D., Wen-Chi Chou, M.D.</span></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span lang="EN-US"><span style="font-size: small;"> </span></span></p> <p style="text-justify: inter-ideograph; text-align: justify; line-height: 200%; text-indent: -6pt; margin: 0cm 0cm 0pt 6pt; mso-char-indent-count: -.5;"><span lang="EN-US"><span style="font-size: small;">Division of Hematology-Oncology, Chang Gung Memorial Hospital,</span></span></p> <p style="text-justify: inter-ideograph; text-align: justify; line-height: 200%; text-indent: -6pt; margin: 0cm 0cm 0pt 6pt; mso-char-indent-count: -.5;"><span lang="EN-US"><span style="font-size: small;">Taoyuan, Taiwan.</span></span></p> <p style="line-height: 200%; margin: 0cm 0cm 0pt;"><strong style="mso-bidi-font-weight: normal;"><span lang="EN-US"><span style="font-size: small;"> </span></span></strong></p> <p style="line-height: 200%; margin: 0cm 0cm 0pt;"><strong style="mso-bidi-font-weight: normal;"><span lang="EN-US"><span style="font-size: small;">Purpose</span></span></strong></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span lang="EN-US"><span style="font-family: Calibri; font-size: small;">Prognostication of life expectancy in terminal cancer is an important issue. The aim of our study was to assess the practical utility of PPI as a prognostic tool by nurse specialist in routine clinical practice in hospice consultation setting to assist with clinical decision making in Taiwan</span></span></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span lang="EN-US"><span style="font-family: Calibri; font-size: small;"> </span></span></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><strong style="mso-bidi-font-weight: normal;"><span lang="EN-US"><span style="font-family: Calibri;"><span style="font-size: small;">Method</span></span></span></strong></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span style="font-family: Calibri;"><span style="font-size: small;"><span lang="EN-US">Total 623 terminal cancer patients under hospice consultation care were enrolled from one medical center in northern Taiwan between</span><span style="mso-hansi-font-family: 鏂扮窗鏄庨珨;" lang="EN-US"> January 1, 2011 and June 30, 2011.</span><strong style="mso-bidi-font-weight: normal;"><span lang="EN-US"> </span></strong><span lang="EN-US">PPI was assessed by nurse specialist at first hospice consultation and categorized into three groups. Patients’ survival were analyzed retrospectively to determine significant between-group differences.<span style="mso-spacerun: yes;"> </span></span></span></span></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span lang="EN-US"><span style="font-family: Calibri; font-size: small;"> </span></span></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><strong style="mso-bidi-font-weight: normal;"><span lang="EN-US"><span style="font-family: Calibri;"><span style="font-size: small;">Result</span></span></span></strong></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span lang="EN-US"><span style="font-size: small;">The PPI sum score assigned 37.2% of all patients to good prognosis group, 18% to intermediate prognosis group and 44.8% to poor prognosis group. The death rate was 56%, 81.2% and 89.6% and median survival was 76, 18 and 7 days in each group respectively. The hazard ratio was 0.19 (95% IC 0.10-0.24, p<0.001) as compared poor prognosis with good prognosis group and 0.54 (95% CI 0.43-0.69, p<0.001) as compared poor prognosis with intermediate prognosis group. The sensitivity and specificity in poor prognosis group was 66% and 71% ; and the positive predictive value and negative predictive value was 81% and 52% for predict patients who died within 21 days (AUC of ROC was 0.68).</span></span></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"> </p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><strong style="mso-bidi-font-weight: normal;"><span lang="EN-US"><span style="font-family: Calibri; font-size: small;">Conclusion</span></span></strong></p> <p style="margin: 0cm 0cm 0pt; tab-stops: 85.5pt;"><span lang="EN-US"><span style="font-family: Calibri; font-size: small;">Survival of terminal cancer patients receiving hospice consultation care can be predicted by different PPI categories. PPI is easy and objective tool and would therefore used by any members of hospice consultation team.</span></span></p> <div class="border-top py-2"><b>Posted by: </b>Wei-Hong Cheng, Fellowship in department of oncology, Chang-Gung Memorial hospital, Taiwan (<span class="f-sm">27-Feb-2012</span>)</div> </div> </div> </div> <div class="container_fluid"> <div class="bg-footer"> <div class="container py-4"> <div class="d-flex justify-content-center pt-4"> <div class="text-center f-sm"> <a href="/" title="Home page" class="text-grey me-2">Home</a><span class="me-1">|</span> <a href="/international-conferences/" title="Conferences" class="text-grey me-1">Conferences</a><span class="me-1">|</span> <a href="/international-exhibitions/" title="International Exhibition" class="text-grey me-2">Exhibitions</a><span class="me-1">|</span> <a href="/event-organizers/" title="Event Organizers" class="text-grey me-2">Organizers</a><span class="me-1">|</span> <a href="/international-venues/" 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