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response</title> <meta name="description" content="Search results for: in-plane response"> <meta name="keywords" content="in-plane response"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="in-plane response"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 5270</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: in-plane response</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5030</span> Dynamic Analysis of Turbo Machinery Foundation for Different Rotating Speed</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sungyani%20Tripathy">Sungyani Tripathy</a>, <a href="https://publications.waset.org/abstracts/search?q=Atul%20Desai"> Atul Desai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Turbo machinery Frame Foundation is very important for power generation, gas, steam, hydro, geothermal and nuclear power plants. The Turbo machinery Foundation system was simulated in SAP: 2000 software and dynamic response of foundation was analysed. In this paper, the detailed study of turbo machinery foundation with different running speed has considered. The different revolution per minute considered in this study is 4000 rpm, 6000 rpm, 8000 rpm, 1000 rpm and 12000 rpm. The above analysis has been carried out considering Winkler spring soil model, solid finite element modelling and dynamic analysis of Turbo machinery foundations. The comparison of frequency and time periods at various mode shapes are addressed in this study. Current work investigates the effect of damping on the response spectra curve at the foundation top deck, considering the dynamic machine load. It has been found that turbo generator foundation with haunches remains more elastic during seismic action for different running speeds. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=turbo%20machinery" title="turbo machinery">turbo machinery</a>, <a href="https://publications.waset.org/abstracts/search?q=SAP%3A%202000" title=" SAP: 2000"> SAP: 2000</a>, <a href="https://publications.waset.org/abstracts/search?q=response%20spectra" title=" response spectra"> response spectra</a>, <a href="https://publications.waset.org/abstracts/search?q=running%20speeds" title=" running speeds"> running speeds</a> </p> <a href="https://publications.waset.org/abstracts/59715/dynamic-analysis-of-turbo-machinery-foundation-for-different-rotating-speed" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59715.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">255</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5029</span> A Sufficient Fuzzy Controller for Improving the Transient Response in Electric Motors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aliasghar%20Baziar">Aliasghar Baziar</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassan%20Masoumi"> Hassan Masoumi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alireza%20Ale%20Saadi"> Alireza Ale Saadi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The control of the response of electric motors plays a significant role in the damping of transient responses. In this regard, this paper presents a static VAR compensator (SVC) based on a fuzzy logic which is applied to an industrial power network consisting of three phase synchronous, asynchronous and DC motor loads. The speed and acceleration variations of a specific machine are the inputs of the proposed fuzzy logic controller (FLC). In order to verify the effectiveness and proficiency of the proposed Fuzzy Logic based SVC (FLSVC), several non-linear time-domain digital simulation tests are performed. The proposed fuzzy model can properly control the response of electric motors. The results show that the FLSVC is successful to improve the voltage profile significantly over a wide range of operating conditions and disturbances thus improving the overall dynamic performance of the network. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fuzzy%20logic%20controller" title="fuzzy logic controller">fuzzy logic controller</a>, <a href="https://publications.waset.org/abstracts/search?q=VAR%20compensator" title=" VAR compensator"> VAR compensator</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20cage%20asynchronous%20motor" title=" single cage asynchronous motor"> single cage asynchronous motor</a>, <a href="https://publications.waset.org/abstracts/search?q=DC%20motor" title=" DC motor"> DC motor</a> </p> <a href="https://publications.waset.org/abstracts/53163/a-sufficient-fuzzy-controller-for-improving-the-transient-response-in-electric-motors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/53163.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">628</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5028</span> Optimization of Spatial Light Modulator to Generate Aberration Free Optical Traps</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Deepak%20K.%20Gupta">Deepak K. Gupta</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20R.%20Ravindran"> T. R. Ravindran</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Holographic Optical Tweezers (HOTs) in general use iterative algorithms such as weighted Gerchberg-Saxton (WGS) to generate multiple traps, which produce traps with 99% uniformity theoretically. But in experiments, it is the phase response of the spatial light modulator (SLM) which ultimately determines the efficiency, uniformity, and quality of the trap spots. In general, SLMs show a nonlinear phase response behavior, and they may even have asymmetric phase modulation depth before and after π. This affects the resolution with which the gray levels are addressed before and after π, leading to a degraded trap performance. We present a method to optimize the SLM for a linear phase response behavior along with a symmetric phase modulation depth around π. Further, we optimize the SLM for its varying phase response over different spatial regions by optimizing the brightness/contrast and gamma of the hologram in different subsections. We show the effect of the optimization on an array of trap spots resulting in improved efficiency and uniformity. We also calculate the spot sharpness metric and trap performance metric and show a tightly focused spot with reduced aberration. The trap performance is compared by calculating the trap stiffness of a trapped particle in a given trap spot before and after aberration correction. The trap stiffness is found to improve by 200% after the optimization. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=spatial%20light%20modulator" title="spatial light modulator">spatial light modulator</a>, <a href="https://publications.waset.org/abstracts/search?q=optical%20trapping" title=" optical trapping"> optical trapping</a>, <a href="https://publications.waset.org/abstracts/search?q=aberration" title=" aberration"> aberration</a>, <a href="https://publications.waset.org/abstracts/search?q=phase%20modulation" title=" phase modulation"> phase modulation</a> </p> <a href="https://publications.waset.org/abstracts/106122/optimization-of-spatial-light-modulator-to-generate-aberration-free-optical-traps" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/106122.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">187</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5027</span> ESS Control Strategy for Primary Frequency Response in Microgrid Considering Ramp Rate </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ho-Jun%20Jo">Ho-Jun Jo</a>, <a href="https://publications.waset.org/abstracts/search?q=Wook-Won%20Kim"> Wook-Won Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Yong-Sung%20Kim"> Yong-Sung Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Jin-O%20Kim"> Jin-O Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The application of ESS (Energy Storage Systems) in the future grids has been the solution of the microgrid. However, high investment costs necessitate accurate modeling and control strategy of ESS to justify its economic viability and further underutilization. Therefore, the reasonable control strategy for ESS which is subjected to generator and usage helps to curtail the cost of investment and operation costs. The rated frequency in power system is decreased when the load is increasing unexpectedly; hence the thermal power is operated at the capacity of only its 95% for the Governor Free (GF) to adjust the frequency as reserve (5%) in practice. The ESS can be utilized with governor at the same time for the frequency response due to characteristic of its fast response speed and moreover, the cost of ESS is declined rapidly to the reasonable price. This paper presents the ESS control strategy to extend usage of the ESS taken account into governor’s ramp rate and reduce the governor’s intervention as well. All results in this paper are simulated by MATLAB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=micro%20grid" title="micro grid">micro grid</a>, <a href="https://publications.waset.org/abstracts/search?q=energy%20storage%20systems" title=" energy storage systems"> energy storage systems</a>, <a href="https://publications.waset.org/abstracts/search?q=ramp%20rate" title=" ramp rate"> ramp rate</a>, <a href="https://publications.waset.org/abstracts/search?q=control%20strategy" title=" control strategy"> control strategy</a> </p> <a href="https://publications.waset.org/abstracts/39143/ess-control-strategy-for-primary-frequency-response-in-microgrid-considering-ramp-rate" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39143.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">392</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5026</span> H∞robust Control Law for a Speed Dc Motor in Both Directions of Rotation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ben%20Abdallah%20Aicha">Ben Abdallah Aicha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this work we show a H∞ synthesis method which enables us to calculate a feedback controller according to considerations of stability robustness and disturbance rejection translated on to the open loop response. However, it may happen that we have an additional specification on the closed loop response relating to tracking of the reference trajectory. The H∞ synthesis has the advantage of offering increased specifications in robustness stability. Implemented for a DC motor, it offers invaluable performance in speed control in both directions of rotation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=H%E2%88%9E%20synthesis" title="H∞ synthesis">H∞ synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=DC%20motor" title=" DC motor"> DC motor</a>, <a href="https://publications.waset.org/abstracts/search?q=robustness%20stability" title=" robustness stability"> robustness stability</a>, <a href="https://publications.waset.org/abstracts/search?q=performance%20conditions" title=" performance conditions"> performance conditions</a> </p> <a href="https://publications.waset.org/abstracts/172911/hrobust-control-law-for-a-speed-dc-motor-in-both-directions-of-rotation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172911.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">84</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5025</span> Behavior of Laminated Plates under Mechanical Loading</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mahmoudi%20Noureddine">Mahmoudi Noureddine</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study the use of two variable refined plate theories of laminated composite plates to static response of laminated plates. The plate theory accounts for parabolic distribution of the transverse shear strains, and satisfies the zero traction boundary conditions on the surfaces of the plate without using shear correction factor. The validity of the present theory is demonstrated by comparison with solutions available in the literature and finite element method. The result is presented for the static response of simply supported rectangular plates under uniform sinusoidal mechanical loadings. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bending" title="bending">bending</a>, <a href="https://publications.waset.org/abstracts/search?q=composite" title=" composite"> composite</a>, <a href="https://publications.waset.org/abstracts/search?q=laminate" title=" laminate"> laminate</a>, <a href="https://publications.waset.org/abstracts/search?q=plates" title=" plates"> plates</a>, <a href="https://publications.waset.org/abstracts/search?q=fem" title=" fem"> fem</a> </p> <a href="https://publications.waset.org/abstracts/30849/behavior-of-laminated-plates-under-mechanical-loading" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30849.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">406</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5024</span> Bayesian Network and Feature Selection for Rank Deficient Inverse Problem</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kyugneun%20Lee">Kyugneun Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Ikjin%20Lee"> Ikjin Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Parameter estimation with inverse problem often suffers from unfavorable conditions in the real world. Useless data and many input parameters make the problem complicated or insoluble. Data refinement and reformulation of the problem can solve that kind of difficulties. In this research, a method to solve the rank deficient inverse problem is suggested. A multi-physics system which has rank deficiency caused by response correlation is treated. Impeditive information is removed and the problem is reformulated to sequential estimations using Bayesian network (BN) and subset groups. At first, subset grouping of the responses is performed. Feature selection with singular value decomposition (SVD) is used for the grouping. Next, BN inference is used for sequential conditional estimation according to the group hierarchy. Directed acyclic graph (DAG) structure is organized to maximize the estimation ability. Variance ratio of response to noise is used to pairing the estimable parameters by each response. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bayesian%20network" title="Bayesian network">Bayesian network</a>, <a href="https://publications.waset.org/abstracts/search?q=feature%20selection" title=" feature selection"> feature selection</a>, <a href="https://publications.waset.org/abstracts/search?q=rank%20deficiency" title=" rank deficiency"> rank deficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=statistical%20inverse%20analysis" title=" statistical inverse analysis"> statistical inverse analysis</a> </p> <a href="https://publications.waset.org/abstracts/75870/bayesian-network-and-feature-selection-for-rank-deficient-inverse-problem" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/75870.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">314</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5023</span> Monitoring of Belt-Drive Defects Using the Vibration Signals and Simulation Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Nabhan">A. Nabhan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20R.%20El-Sharkawy"> Mohamed R. El-Sharkawy</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Rashed"> A. Rashed </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The main aim of this paper is to dedicate the belt drive system faults like cogs missing, misalignment and belt worm using vibration analysis technique. Experimentally, the belt drive test-rig is equipped to measure vibrations signals under different operating conditions. Finite element 3D model of belt drive system is created and vibration response analyzed using commercial finite element software ABAQUS/CAE.  Root mean square (RMS) and Crest Factor will serve as indicators of average amplitude of envelope analysis signals. The vibration signals pattern obtained from the simulation model and experimental data have the same characteristics. It can be concluded that each case of the RMS is more effective in detecting the defect for acceleration response. While Crest Factor parameter has a response with the displacement and velocity of vibration signals. Also it can be noticed that the model has difficulty in completing the solution when the misalignment angle is higher than 1 degree. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=simulation%20model" title="simulation model">simulation model</a>, <a href="https://publications.waset.org/abstracts/search?q=misalignment" title=" misalignment"> misalignment</a>, <a href="https://publications.waset.org/abstracts/search?q=cogs%20missing" title=" cogs missing"> cogs missing</a>, <a href="https://publications.waset.org/abstracts/search?q=vibration%20analysis" title=" vibration analysis"> vibration analysis</a> </p> <a href="https://publications.waset.org/abstracts/98593/monitoring-of-belt-drive-defects-using-the-vibration-signals-and-simulation-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98593.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">284</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5022</span> Non-Linear Load-Deflection Response of Shape Memory Alloys-Reinforced Composite Cylindrical Shells under Uniform Radial Load</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Behrang%20Tavousi%20Tehrani">Behrang Tavousi Tehrani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad-Zaman%20Kabir"> Mohammad-Zaman Kabir</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Shape memory alloys (SMA) are often implemented in smart structures as the active components. Their ability to recover large displacements has been used in many applications, including structural stability/response enhancement and active structural acoustic control. SMA wires or fibers can be embedded with composite cylinders to increase their critical buckling load, improve their load-deflection behavior, and reduce the radial deflections under various thermo-mechanical loadings. This paper presents a semi-analytical investigation on the non-linear load-deflection response of SMA-reinforced composite circular cylindrical shells. The cylinder shells are under uniform external pressure load. Based on first-order shear deformation<em> shell theory (FSDT),</em> the equilibrium equations of the structure are derived. One-dimensional simplified Brinson’s model is used for determining the SMA recovery force due to its simplicity and accuracy. Airy stress function and Galerkin technique are used to obtain non-linear load-deflection curves. The results are verified by comparing them with those in the literature. Several parametric studies are conducted in order to investigate the effect of SMA volume fraction, SMA pre-strain value, and SMA activation temperature on the response of the structure. It is shown that suitable usage of SMA wires results in a considerable enhancement in the load-deflection response of the shell due to the generation of the SMA tensile recovery force. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=airy%20stress%20function" title="airy stress function">airy stress function</a>, <a href="https://publications.waset.org/abstracts/search?q=cylindrical%20shell" title=" cylindrical shell"> cylindrical shell</a>, <a href="https://publications.waset.org/abstracts/search?q=Galerkin%20technique" title=" Galerkin technique"> Galerkin technique</a>, <a href="https://publications.waset.org/abstracts/search?q=load-deflection%20curve" title=" load-deflection curve"> load-deflection curve</a>, <a href="https://publications.waset.org/abstracts/search?q=recovery%20stress" title=" recovery stress"> recovery stress</a>, <a href="https://publications.waset.org/abstracts/search?q=shape%20memory%20alloy" title=" shape memory alloy"> shape memory alloy</a> </p> <a href="https://publications.waset.org/abstracts/96718/non-linear-load-deflection-response-of-shape-memory-alloys-reinforced-composite-cylindrical-shells-under-uniform-radial-load" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96718.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">188</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5021</span> Reduced Glycaemic Impact by Kiwifruit-Based Carbohydrate Exchanges Depends on Both Available Carbohydrate and Non-Digestible Fruit Residue</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Mishra">S. Mishra</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Monro"> J. Monro</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Edwards"> H. Edwards</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Podd"> J. Podd </a> </p> <p class="card-text"><strong>Abstract:</strong></p> When a fruit such as kiwifruit is consumed its tissues are released from the physical /anatomical constraints existing in the fruit. During digestion they may expand several-fold to achieve a hydrated solids volume far greater than the original fruit, and occupy the available space in the gut, where they surround and interact with other food components. Within the cell wall dispersion, in vitro digestion of co-consumed carbohydrate, diffusion of digestion products, and mixing responsible for mass transfer of nutrients to the gut wall for absorption, were all retarded. All of the foregoing processes may be involved in the glycaemic response to carbohydrate foods consumed with kiwifruit, such as breakfast cereal. To examine their combined role in reducing the glycaemic response to wheat cereal consumed with kiwifruit we formulated diets containing equal amounts of breakfast cereal, with the addition of either kiwifruit, or sugars of the same composition and quantity as in kiwifruit. Therefore, the only difference between the diets was the presence of non-digestible fruit residues. The diet containing the entire disperse kiwifruit significantly reduced the glycaemic response amplitude and the area under the 0-120 min incremental blood glucose response curve (IAUC), compared with the equicarbohydrate diet containing the added kiwifruit sugars. It also slightly but significantly increased the 120-180 min IAUC by preventing a postprandial overcompensation, indicating improved homeostatic blood glucose control. In a subsequent study in which we used kiwifruit in a carbohydrate exchange format, in which the kiwifruit carbohydrate partially replaced breakfast cereal in equal carbohydrate meals, the blood glucose was further reduced without a loss of satiety, and with a reduction in insulin demand. The results show that kiwifruit may be a valuable component in low glycaemic impact diets. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbohydrate" title="carbohydrate">carbohydrate</a>, <a href="https://publications.waset.org/abstracts/search?q=digestion" title=" digestion"> digestion</a>, <a href="https://publications.waset.org/abstracts/search?q=glycaemic%20response" title=" glycaemic response"> glycaemic response</a>, <a href="https://publications.waset.org/abstracts/search?q=kiwifruit" title=" kiwifruit"> kiwifruit</a> </p> <a href="https://publications.waset.org/abstracts/30851/reduced-glycaemic-impact-by-kiwifruit-based-carbohydrate-exchanges-depends-on-both-available-carbohydrate-and-non-digestible-fruit-residue" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30851.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">495</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5020</span> Simulation of a Cost Model Response Requests for Replication in Data Grid Environment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kaddi%20Mohammed">Kaddi Mohammed</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Benatiallah"> A. Benatiallah</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Benatiallah"> D. Benatiallah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Data grid is a technology that has full emergence of new challenges, such as the heterogeneity and availability of various resources and geographically distributed, fast data access, minimizing latency and fault tolerance. Researchers interested in this technology address the problems of the various systems related to the industry such as task scheduling, load balancing and replication. The latter is an effective solution to achieve good performance in terms of data access and grid resources and better availability of data cost. In a system with duplication, a coherence protocol is used to impose some degree of synchronization between the various copies and impose some order on updates. In this project, we present an approach for placing replicas to minimize the cost of response of requests to read or write, and we implement our model in a simulation environment. The placement techniques are based on a cost model which depends on several factors, such as bandwidth, data size and storage nodes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=response%20time" title="response time">response time</a>, <a href="https://publications.waset.org/abstracts/search?q=query" title=" query"> query</a>, <a href="https://publications.waset.org/abstracts/search?q=consistency" title=" consistency"> consistency</a>, <a href="https://publications.waset.org/abstracts/search?q=bandwidth" title=" bandwidth"> bandwidth</a>, <a href="https://publications.waset.org/abstracts/search?q=storage%20capacity" title=" storage capacity"> storage capacity</a>, <a href="https://publications.waset.org/abstracts/search?q=CERN" title=" CERN"> CERN</a> </p> <a href="https://publications.waset.org/abstracts/47895/simulation-of-a-cost-model-response-requests-for-replication-in-data-grid-environment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47895.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">271</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5019</span> Transcriptomic Response of Calmodulin Encoding Gene (CaM) in Pesticide Utilizing Talaromyces Fungal Strains </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20D.%20Asemoloye">M. D. Asemoloye</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20G.%20Jonathan"> S. G. Jonathan</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Rafiq"> A. Rafiq</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20J.%20Olawuyi"> O. J. Olawuyi</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20O.%20Adejoye"> D. O. Adejoye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Calmodulin is one of the intracellular calcium proteins that regulates large spectrum of enzymes and cellular functions including metabolism of cyclic nucleotides and glycogen. The potentials of calmodulin gene in fungi necessitates their genetic response and their strong cassette of enzyme secretions for pesticide degradation. Therefore, this study was carried out to investigate the ‘Transcriptomic’ response of calmodulin encoding genes in Talaromyces fungi in response to 2, 2-dichlorovinyl dimethyl phosphate (DDVP or Dichlorvos) an organophosphate pesticide and γ-Hexachlorocyclohexane (Lindane) an organochlorine pesticide. Fungi strains isolated from rhizosphere from grasses rhizosphere in pesticide polluted sites were subjected to percentage incidence test. Two most frequent fungi were further characterized using ITS gene amplification (ITS1 and ITS4 combinations), they were thereafter subjected to In-vitro DDVP and lindane tolerance tests at different concentrations. They were also screened for presence and expression of calmodulin gene (caM) using RT-PCR technique. The two Talaromyces strains had the highest incidence of 50-72% in pesticide polluted site, they were both identified as Talaromyces astroroseus asemoG and Talaromyces purpurogenum asemoN submitted in NCBI gene-bank with accession numbers KY488464 and KY488468 respectively. T. astroroseus KY488464 tolerated DDVP (1.23±0.023 cm) and lindane (1.11±0.018 cm) at 25 % concentration while T. purpurogenum KY488468 tolerated DDVP (1.33±0.061 cm) and lindane (1.54±0.077 cm) at this concentration. Calmodulin gene was detected in both strains, but RT-PCR expression of caM gene revealed at 900-1000 bp showed an under-expression of caM in T. astrorosues KY488464 but overexpressed in T. purpurogenum KY488464. Thus, the calmodulin gene response of these fungal strains to both pesticides could be considered in monitoring the potentials of fungal strains to pesticide tolerance and bioremediation of pesticide in polluted soil. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Calmodulin%20gene" title="Calmodulin gene">Calmodulin gene</a>, <a href="https://publications.waset.org/abstracts/search?q=pesticide" title=" pesticide"> pesticide</a>, <a href="https://publications.waset.org/abstracts/search?q=RT-PCR" title=" RT-PCR"> RT-PCR</a>, <a href="https://publications.waset.org/abstracts/search?q=talaromyces" title=" talaromyces"> talaromyces</a>, <a href="https://publications.waset.org/abstracts/search?q=tolerance" title=" tolerance"> tolerance</a> </p> <a href="https://publications.waset.org/abstracts/77765/transcriptomic-response-of-calmodulin-encoding-gene-cam-in-pesticide-utilizing-talaromyces-fungal-strains" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77765.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">225</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5018</span> Analytical Response Characterization of High Mobility Transistor Channels</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F.%20Z.%20Mahi">F. Z. Mahi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Marinchio"> H. Marinchio</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Palermo"> C. Palermo</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Varani"> L. Varani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We propose an analytical approach for the admittance response calculation of the high mobility InGaAs channel transistors. The development of the small-signal admittance takes into account the longitudinal and transverse electric fields through a pseudo two-dimensional approximation of the Poisson equation. The total currents and the potentials matrix relation between the gate and the drain terminals determine the frequency-dependent small-signal admittance response. The analytical results show that the admittance spectrum exhibits a series of resonant peaks corresponding to the excitation of plasma waves. The appearance of the resonance is discussed and analyzed as functions of the channel length and the temperature. The model can be used, on one hand, to control the appearance of plasma resonances, and on the other hand, can give significant information about the admittance phase frequency dependence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=small-signal%20admittance" title="small-signal admittance">small-signal admittance</a>, <a href="https://publications.waset.org/abstracts/search?q=Poisson%20equation" title=" Poisson equation"> Poisson equation</a>, <a href="https://publications.waset.org/abstracts/search?q=currents%20and%20potentials%20matrix" title=" currents and potentials matrix"> currents and potentials matrix</a>, <a href="https://publications.waset.org/abstracts/search?q=the%20drain%20and%20the%20gate%20terminals" title=" the drain and the gate terminals"> the drain and the gate terminals</a>, <a href="https://publications.waset.org/abstracts/search?q=analytical%20model" title=" analytical model"> analytical model</a> </p> <a href="https://publications.waset.org/abstracts/35861/analytical-response-characterization-of-high-mobility-transistor-channels" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35861.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">540</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5017</span> Screening Active Components in YPFS for Regulating Initiative Key Factors in Allergic Inflammation </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dandan%20Shen">Dandan Shen</a>, <a href="https://publications.waset.org/abstracts/search?q=Hui-zhu%20Wang"> Hui-zhu Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Xi%20Yu"> Xi Yu</a>, <a href="https://publications.waset.org/abstracts/search?q=LiLi%20Gui"> LiLi Gui</a>, <a href="https://publications.waset.org/abstracts/search?q=Xiao%20Wei"> Xiao Wei</a>, <a href="https://publications.waset.org/abstracts/search?q=Xiao-yan%20Jiang"> Xiao-yan Jiang</a>, <a href="https://publications.waset.org/abstracts/search?q=Da-wei%20Wang"> Da-wei Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Min%20Hong"> Min Hong </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Yu-ping-feng-san (YPFS) is a clinical medicine for asthma and other allergic diseases, but the mechanism of YPFS on relapse of allergy is unclear. Currently, people come to realize the epithelial cells(EC) play a key role in stimulating and regulating local immune response. The study of thymic stromal lymphopoietin（TSLP derived from EC provides an important evidence that the EC can regulate immune response to stimulate allergic response. In this study, we observed the effect of YPFS on TSLP in vivo and in vitro. We established a method by using bronchial epithelial cells (16HBE) for screening potential bioactive components by HPLC-MS in YPFS and then analyzed the components in serum containing YPFS by UPLC-MS. The results showed that YPFS could decrease TSLP protein level in OVA-sensitized mice and 16HBE cells. Five components combing with the 16HBE cells were both detected in the serum. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=TSLP" title="TSLP">TSLP</a>, <a href="https://publications.waset.org/abstracts/search?q=bronchial%20epithelial%20cells" title=" bronchial epithelial cells"> bronchial epithelial cells</a>, <a href="https://publications.waset.org/abstracts/search?q=cell-binding" title=" cell-binding"> cell-binding</a>, <a href="https://publications.waset.org/abstracts/search?q=drug-containing%20serum" title=" drug-containing serum"> drug-containing serum</a> </p> <a href="https://publications.waset.org/abstracts/2924/screening-active-components-in-ypfs-for-regulating-initiative-key-factors-in-allergic-inflammation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2924.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">512</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5016</span> Vertical and Lateral Vibration Response for Corrugated Track Curves Supported on High-Density Polyethylene and Hytrel Rail Pads</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=B.M.%20Balekwa">B.M. Balekwa</a>, <a href="https://publications.waset.org/abstracts/search?q=D.V.V.%20Kallon"> D.V.V. Kallon</a>, <a href="https://publications.waset.org/abstracts/search?q=D.J.%20Fourie"> D.J. Fourie</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Modal analysis is applied to establish the dynamic difference between vibration response of the rails supported on High Density Polyethylene (HDPE) and Hytrel/6358 rail pads. The experiment was conducted to obtain the results in the form of Frequency Response Functions (FRFs) in the vertical and lateral directions. Three antiresonance modes are seen in the vertical direction; one occurs at about 150 Hz when the rail resting on the Hytrel/6358 pad experiences a force mid-span. For the rail resting on this type of rail pad, no antiresonance occurs when the force is applied on the point of the rail that is resting on the pad and directly on top of a sleeper. The two antiresonance modes occur in a frequency range of 250 – 300 Hz in the vertical direction for the rail resting on HDPE pads. At resonance, the rail vibrates with a higher amplitude, but at antiresonance, the rail transmits vibration downwards to the sleepers. When the rail is at antiresonance, the stiffness of the rail pads play a vital role in terms of damping the vertical vibration to protect the sleepers. From the FRFs it is understood that the Hytrel/6358 rail pads perform better than the HDPE in terms of vertical response, given that at a lower frequency range of 0 – 300 Hz only one antiresonance mode was identified for vertical vibration of the rail supported on Hytrel/6358. This means the rail is at antiresonance only once within this frequency range and this is the only time when vibration is transmitted downwards. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=accelerance" title="accelerance">accelerance</a>, <a href="https://publications.waset.org/abstracts/search?q=FRF" title=" FRF"> FRF</a>, <a href="https://publications.waset.org/abstracts/search?q=rail%20corrugation" title=" rail corrugation"> rail corrugation</a>, <a href="https://publications.waset.org/abstracts/search?q=rail%20pad" title=" rail pad"> rail pad</a> </p> <a href="https://publications.waset.org/abstracts/125399/vertical-and-lateral-vibration-response-for-corrugated-track-curves-supported-on-high-density-polyethylene-and-hytrel-rail-pads" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/125399.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">177</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5015</span> Peak Floor Response for Buildings with Flexible Base</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Luciano%20Roberto%20Fernandez-Sola">Luciano Roberto Fernandez-Sola</a>, <a href="https://publications.waset.org/abstracts/search?q=Cesar%20Augusto%20Arredondo-Velez"> Cesar Augusto Arredondo-Velez</a>, <a href="https://publications.waset.org/abstracts/search?q=Miguel%20Angel%20Jaimes-Tellez"> Miguel Angel Jaimes-Tellez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper explores the modifications on peak acceleration, velocity and displacement profiles over the structure due to dynamic soil-structure interaction (DSSI). A shear beam model is used for the structure. Soil-foundation flexibility (inertial interaction) is considered by a set of springs and dashpots at the structure base. Kinematic interaction is considered using transfer functions. Impedance functions are computed using simplified expressions for rigid foundations. The research studies the influence of the slenderness ratio on the value of the peak floor response. It is shown that the modifications of peak floor responses are not the same for acceleration, velocity and displacement. This is opposite to the hypothesis used by methods included in several building codes. Results show that modifications produced by DSSI on different response quantities are not equal. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=peak%20floor%20intensities" title="peak floor intensities">peak floor intensities</a>, <a href="https://publications.waset.org/abstracts/search?q=dynamic%20soil-structure%20interaction" title=" dynamic soil-structure interaction"> dynamic soil-structure interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=buildings%20with%20flexible%20base" title=" buildings with flexible base"> buildings with flexible base</a>, <a href="https://publications.waset.org/abstracts/search?q=kinematic%20and%20inertial%20interaction" title=" kinematic and inertial interaction"> kinematic and inertial interaction</a> </p> <a href="https://publications.waset.org/abstracts/65705/peak-floor-response-for-buildings-with-flexible-base" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65705.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">450</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5014</span> Seismic Response Analysis of Frame Structures Based on Super Joint Element Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Li%20Xu">Li Xu</a>, <a href="https://publications.waset.org/abstracts/search?q=Yang%20Hong"> Yang Hong</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20Zhao%20Wen"> T. Zhao Wen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Experimental results of many RC beam-column subassemblage indicate that slippage of longitudinal beam rebar within the joint and the shear deformation of joint core have significant influence on seismic behavior of the subassemblage. However, rigid joint assumption has been generally used in the seismic response analysis of RC frames, in which two kinds of inelastic deformation of joint have been ignored. Based on OpenSees platform, ‘Super Joint Element Model’ with more detailed inelastic mechanism is used to simulate the inelastic response of joints. Two finite element models of typical RC plane frame, namely considering or ignoring the inelastic deformation of joint respectively, were established and analyzed under seven strong earthquake waves. The simulated global and local inelastic deformations of the RC plane frame is shown and discussed. The analyses also confirm the security of the earthquake-resistant frame designed according to Chinese codes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=frame%20structure" title="frame structure">frame structure</a>, <a href="https://publications.waset.org/abstracts/search?q=beam-column%20joint" title=" beam-column joint"> beam-column joint</a>, <a href="https://publications.waset.org/abstracts/search?q=longitudinal%20bar%20slippage" title=" longitudinal bar slippage"> longitudinal bar slippage</a>, <a href="https://publications.waset.org/abstracts/search?q=shear%20deformation" title=" shear deformation"> shear deformation</a>, <a href="https://publications.waset.org/abstracts/search?q=nonlinear%20analysis" title=" nonlinear analysis"> nonlinear analysis</a> </p> <a href="https://publications.waset.org/abstracts/70780/seismic-response-analysis-of-frame-structures-based-on-super-joint-element-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70780.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">409</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5013</span> Studying the Dynamical Response of Nano-Microelectromechanical Devices for Nanomechanical Testing of Nanostructures</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Reza%20Zamani%20Kouhpanji">Mohammad Reza Zamani Kouhpanji</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Characterizing the fatigue and fracture properties of nanostructures is one of the most challenging tasks in nanoscience and nanotechnology due to lack of a MEMS/NEMS device for generating uniform cyclic loadings at high frequencies. Here, the dynamic response of a recently proposed MEMS/NEMS device under different inputs signals is completely investigated. This MEMS/NEMS device is designed and modeled based on the electromagnetic force induced between paired parallel wires carrying electrical currents, known as Ampere’s Force Law (AFL). Since this MEMS/NEMS device only uses two paired wires for actuation part and sensing part, it represents highly sensitive and linear response for nanostructures with any stiffness and shapes (single or arrays of nanowires, nanotubes, nanosheets or nanowalls). In addition to studying the maximum gains at different resonance frequencies of the MEMS/NEMS device, its dynamical responses are investigated for different inputs and nanostructure properties to demonstrate the capability, usability, and reliability of the device for wide range of nanostructures. This MEMS/NEMS device can be readily integrated into SEM/TEM instruments to provide real time study of the fatigue and fracture properties of nanostructures as well as their softening or hardening behaviors, and initiation and/or propagation of nanocracks in them. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MEMS%2FNEMS%20devices" title="MEMS/NEMS devices">MEMS/NEMS devices</a>, <a href="https://publications.waset.org/abstracts/search?q=paired%20wire%20actuators%20and%20sensors" title=" paired wire actuators and sensors"> paired wire actuators and sensors</a>, <a href="https://publications.waset.org/abstracts/search?q=dynamical%20response" title=" dynamical response"> dynamical response</a>, <a href="https://publications.waset.org/abstracts/search?q=fatigue%20and%20fracture%20characterization" title=" fatigue and fracture characterization"> fatigue and fracture characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=Ampere%E2%80%99s%20force%20law" title=" Ampere’s force law"> Ampere’s force law</a> </p> <a href="https://publications.waset.org/abstracts/82093/studying-the-dynamical-response-of-nano-microelectromechanical-devices-for-nanomechanical-testing-of-nanostructures" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82093.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">399</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5012</span> Examining Effects of Electronic Market Functions on Decrease in Product Unit Cost and Response Time to Customer </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maziyar%20Nouraee">Maziyar Nouraee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Electronic markets in recent decades contribute remarkably in business transactions. Many organizations consider traditional ways of trade non-economical and therefore they do trade only through electronic markets. There are different categorizations of electronic markets functions. In one classification, functions of electronic markets are categorized into classes as information, transactions, and value added. In the present paper, effects of the three classes on the two major elements of the supply chain management are measured. The two elements are decrease in the product unit cost and reduction in response time to the customer. The results of the current research show that among nine minor elements related to the three classes of electronic markets functions, six factors and three factors influence on reduction of the product unit cost and reduction of response time to the customer, respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electronic%20commerce" title="electronic commerce">electronic commerce</a>, <a href="https://publications.waset.org/abstracts/search?q=electronic%20market" title=" electronic market"> electronic market</a>, <a href="https://publications.waset.org/abstracts/search?q=B2B%20trade" title=" B2B trade"> B2B trade</a>, <a href="https://publications.waset.org/abstracts/search?q=supply%20chain%20management" title=" supply chain management"> supply chain management</a> </p> <a href="https://publications.waset.org/abstracts/3231/examining-effects-of-electronic-market-functions-on-decrease-in-product-unit-cost-and-response-time-to-customer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3231.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">392</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5011</span> Melanoma Antigen Proteins Are Involved in DNA Damage Response</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Olivier%20de%20Backer">Olivier de Backer</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexis%20Khelfi"> Alexis Khelfi</a>, <a href="https://publications.waset.org/abstracts/search?q=Olivier%20Svensek"> Olivier Svensek</a>, <a href="https://publications.waset.org/abstracts/search?q=Axelle%20Nolmans"> Axelle Nolmans</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominique%20Desnoeck"> Dominique Desnoeck</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The SMC5-SMC6 complex helps replication and repair of DNA double-strand breaks. Nse1, Nse3 and Nse4 are non-SMC components of the complex in which Nse3 stimulates the E3 ubiquitin ligase activity of Nse1 and is required for recruiting the complex on DNA. In most eukaryotes, Nse3 is a single protein, but in eutherians (placental mammals), it belongs to a large family of proteins called MAGE (Melanoma antigen) that share a conserved domain of about 200 aa known as MHD (Mage homology domain). MAGE assembles specific RING and HECT ubiquitin ligases and determines new substrates for ubiquitination. The MHD is required for the interaction with the cognate E3 ligase. Some MAGEs (referred to as Type I) are exclusively expressed in germ cells of the testis but are often expressed ectopically in cancer cells as the result of epigenetic modifications. The 12 MAGE-A genes belong to this category. Serval MAGE-A proteins could promote tumorigenesis by targeting tumor suppressor proteins (including p53) for ubiquitination and degradation. We showed that depletion of MAGE-A proteins in melanoma cells results in impaired DNA damage response and increased double-strand breaks after exposure to camptothecin. Moreover, it was shown that other actors of the DNA Damage Response were impacted when cells were depleted of MAGEA proteins. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DNA%20damage%20response" title="DNA damage response">DNA damage response</a>, <a href="https://publications.waset.org/abstracts/search?q=melanoma" title=" melanoma"> melanoma</a>, <a href="https://publications.waset.org/abstracts/search?q=camptothecin" title=" camptothecin"> camptothecin</a>, <a href="https://publications.waset.org/abstracts/search?q=new%20role" title=" new role"> new role</a>, <a href="https://publications.waset.org/abstracts/search?q=MAGEA" title=" MAGEA"> MAGEA</a> </p> <a href="https://publications.waset.org/abstracts/169692/melanoma-antigen-proteins-are-involved-in-dna-damage-response" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169692.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">101</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5010</span> Rescue Emergency Drone for Fast Response to Medical Emergencies Due to Traffic Accidents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anders%20S.%20Kristensen">Anders S. Kristensen</a>, <a href="https://publications.waset.org/abstracts/search?q=Dewan%20Ahsan"> Dewan Ahsan</a>, <a href="https://publications.waset.org/abstracts/search?q=Saqib%20Mehmood"> Saqib Mehmood</a>, <a href="https://publications.waset.org/abstracts/search?q=Shakeel%20Ahmed"> Shakeel Ahmed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Traffic accidents are a result of the convergence of hazards, malfunctioning of vehicles and human negligence that have adverse economic and health impacts and effects. Unfortunately, avoiding them completely is very difficult, but with quick response to rescue and first aid, the mortality rate of inflicted persons can be reduced significantly. Smart and innovative technologies can play a pivotal role to respond faster to traffic crash emergencies comparing conventional means of transportation. For instance, Rescue Emergency Drone (RED) can provide faster and real-time crash site risk assessment to emergency medical services, thereby helping them to quickly and accurately assess a situation, dispatch the right equipment and assist bystanders to treat inflicted person properly. To conduct a research in this regard, the case of a traffic roundabout that is prone to frequent traffic accidents on the outskirts of Esbjerg, a town located on western coast of Denmark is hypothetically considered. Along with manual calculations, Emergency Disaster Management Simulation (EDMSIM) has been used to verify the response time of RED from a fire station of the town to the presumed crash site. The results of the study demonstrate the robustness of RED into emergency services to help save lives. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=automated%20external%20defibrillator" title="automated external defibrillator">automated external defibrillator</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20emergency" title=" medical emergency"> medical emergency</a>, <a href="https://publications.waset.org/abstracts/search?q=response%20time" title=" response time"> response time</a>, <a href="https://publications.waset.org/abstracts/search?q=unmanned%20aerial%20system" title=" unmanned aerial system"> unmanned aerial system</a> </p> <a href="https://publications.waset.org/abstracts/81258/rescue-emergency-drone-for-fast-response-to-medical-emergencies-due-to-traffic-accidents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/81258.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">228</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5009</span> Soil-Structure Interaction in Stiffness and Strength Degrading Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Enrique%20Bazan-Zurita">Enrique Bazan-Zurita</a>, <a href="https://publications.waset.org/abstracts/search?q=Sittipong%20Jarernprasert"> Sittipong Jarernprasert</a>, <a href="https://publications.waset.org/abstracts/search?q=Jacobo%20Bielak"> Jacobo Bielak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We study the effects of soil-structure interaction (SSI) on the inelastic seismic response of a single-degree-of-freedom system whose hysteretic behaviour exhibits stiffness and/or strength degrading characteristics. Two sets of accelerograms are used as seismic input: the first comprising 87 record from stiff to medium stiff sites in California, and the second comprising 66 records from the soft lakebed of Mexico City. This study focuses in three seismic response parameters: ductility demand, inter-story drift, and total lateral displacement. The results allow quantitative estimates of changes in such parameters in an SSI system in comparison with those corresponding to the associated fixed-base system. We found that degrading features affect significantly both the response of fixed-base structures and the impact of soil-structure interaction. We propose a procedure to incorporate the results of this and similar studies in seismic design regulations for SSI system with anticipated nonlinear degrading behaviour. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=inelastic" title="inelastic">inelastic</a>, <a href="https://publications.waset.org/abstracts/search?q=seismic" title=" seismic"> seismic</a>, <a href="https://publications.waset.org/abstracts/search?q=building" title=" building"> building</a>, <a href="https://publications.waset.org/abstracts/search?q=foundation" title=" foundation"> foundation</a>, <a href="https://publications.waset.org/abstracts/search?q=interaction" title=" interaction"> interaction</a> </p> <a href="https://publications.waset.org/abstracts/7045/soil-structure-interaction-in-stiffness-and-strength-degrading-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7045.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">286</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5008</span> Seismic Response and Sensitivity Analysis of Circular Shallow Tunnels</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Siti%20Khadijah%20Che%20Osmi">Siti Khadijah Che Osmi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Ahmad%20Syed"> Mohammed Ahmad Syed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Underground tunnels are one of the most popular public facilities for various applications such as transportation, water transfer, network utilities and etc. Experience from the past earthquake reveals that the underground tunnels also become vulnerable components and may damage at certain percentage depending on the level of ground shaking and induced phenomena. In this paper a numerical analysis is conducted in evaluating the sensitivity of two types of circular shallow tunnel lining models to wide ranging changes in the geotechnical design parameter. Critical analysis has been presented about the current methods of analysis, structural typology, ground motion characteristics, effect of soil conditions and associated uncertainties on the tunnel integrity. The response of the tunnel is evaluated through 2D non-linear finite element analysis, which critically assesses the impact of increasing levels of seismic loads. The finding from this study offer significant information on improving methods to assess the vulnerability of underground structures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=geotechnical%20design%20parameter" title="geotechnical design parameter">geotechnical design parameter</a>, <a href="https://publications.waset.org/abstracts/search?q=seismic%20response" title=" seismic response"> seismic response</a>, <a href="https://publications.waset.org/abstracts/search?q=sensitivity%20analysis" title=" sensitivity analysis"> sensitivity analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=shallow%20tunnel" title=" shallow tunnel"> shallow tunnel</a> </p> <a href="https://publications.waset.org/abstracts/27943/seismic-response-and-sensitivity-analysis-of-circular-shallow-tunnels" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27943.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">441</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5007</span> An Investigation on Material Removal Rate of EDM Process: A Response Surface Methodology Approach</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Azhar%20Equbal">Azhar Equbal</a>, <a href="https://publications.waset.org/abstracts/search?q=Anoop%20Kumar%20Sood"> Anoop Kumar Sood</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Asif%20Equbal"> M. Asif Equbal</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Israr%20Equbal"> M. Israr Equbal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the present work response surface methodology (RSM) based central composite design (CCD) is used for analyzing the electrical discharge machining (EDM) process. For experimentation, mild steel is selected as work piece and copper is used as electrode. Three machining parameters namely current (I), spark on time (T<sub>on</sub>) and spark off time (T<sub>off</sub>) are selected as the input variables. The output or response chosen is material removal rate (MRR) which is to be maximized. To reduce the number of runs face centered central composite design (FCCCD) was used. ANOVA was used to determine the significance of parameter and interactions. The suitability of model is tested using Anderson darling (AD) plot. The results conclude that different parameters considered i.e. current, pulse on and pulse off time; all have dominant effect on the MRR. At last, the optimized parameter setting for maximizing MRR is found through main effect plot analysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=EDM" title="EDM">EDM</a>, <a href="https://publications.waset.org/abstracts/search?q=electrode" title=" electrode"> electrode</a>, <a href="https://publications.waset.org/abstracts/search?q=MRR" title=" MRR"> MRR</a>, <a href="https://publications.waset.org/abstracts/search?q=RSM" title=" RSM"> RSM</a>, <a href="https://publications.waset.org/abstracts/search?q=ANOVA" title=" ANOVA"> ANOVA</a> </p> <a href="https://publications.waset.org/abstracts/64576/an-investigation-on-material-removal-rate-of-edm-process-a-response-surface-methodology-approach" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64576.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5006</span> Comparison of Equivalent Linear and Non-Linear Site Response Model Performance in Kathmandu Valley</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sajana%20Suwal">Sajana Suwal</a>, <a href="https://publications.waset.org/abstracts/search?q=Ganesh%20R.%20Nhemafuki"> Ganesh R. Nhemafuki</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Evaluation of ground response under earthquake shaking is crucial in geotechnical earthquake engineering. Damage due to seismic excitation is mainly correlated to local geological and geotechnical conditions. It is evident from the past earthquakes (e.g. 1906 San Francisco, USA, 1923 Kanto, Japan) that the local geology has strong influence on amplitude and duration of ground motions. Since then significant studies has been conducted on ground motion amplification revealing the importance of influence of local geology on ground. Observations from the damaging earthquakes (e.g. Nigata and San Francisco, 1964; Irpinia, 1980; Mexico, 1985; Kobe, 1995; L’Aquila, 2009) divulged that non-uniform damage pattern, particularly in soft fluvio-lacustrine deposit is due to the local amplification of seismic ground motion. Non-uniform damage patterns are also observed in Kathmandu Valley during 1934 Bihar Nepal earthquake and recent 2015 Gorkha earthquake seemingly due to the modification of earthquake ground motion parameters. In this study, site effects resulting from amplification of soft soil in Kathmandu are presented. A large amount of subsoil data was collected and used for defining the appropriate subsoil model for the Kathamandu valley. A comparative study of one-dimensional total-stress equivalent linear and non-linear site response is performed using four strong ground motions for six sites of Kathmandu valley. In general, one-dimensional (1D) site-response analysis involves the excitation of a soil profile using the horizontal component and calculating the response at individual soil layers. In the present study, both equivalent linear and non-linear site response analyses were conducted using the computer program DEEPSOIL. The results show that there is no significant deviation between equivalent linear and non-linear site response models until the maximum strain reaches to 0.06-0.1%. Overall, it is clearly observed from the results that non-linear site response model perform better as compared to equivalent linear model. However, the significant deviation between two models is resulted from other influencing factors such as assumptions made in 1D site response, lack of accurate values of shear wave velocity and nonlinear properties of the soil deposit. The results are also presented in terms of amplification factors which are predicted to be around four times more in case of non-linear analysis as compared to equivalent linear analysis. Hence, the nonlinear behavior of soil prevails the urgent need of study of dynamic characteristics of the soft soil deposit that can specifically represent the site-specific design spectra for the Kathmandu valley for building resilient structures from future damaging earthquakes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=deep%20soil" title="deep soil">deep soil</a>, <a href="https://publications.waset.org/abstracts/search?q=equivalent%20linear%20analysis" title=" equivalent linear analysis"> equivalent linear analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=non-linear%20analysis" title=" non-linear analysis"> non-linear analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=site%20response" title=" site response"> site response</a> </p> <a href="https://publications.waset.org/abstracts/71531/comparison-of-equivalent-linear-and-non-linear-site-response-model-performance-in-kathmandu-valley" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/71531.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">291</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5005</span> Photo Electrical Response in Graphene Based Resistive Sensor</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20C.%20Woo">H. C. Woo</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Bouanis"> F. Bouanis</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20S.%20Cojocaur"> C. S. Cojocaur</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Graphene, which consists of a single layer of carbon atoms in a honeycomb lattice, is an interesting potential optoelectronic material because of graphene’s high carrier mobility, zero bandgap, and electron–hole symmetry. Graphene can absorb light and convert it into a photocurrent over a wide range of the electromagnetic spectrum, from the ultraviolet to visible and infrared regimes. Over the last several years, a variety of graphene-based photodetectors have been reported, such as graphene transistors, graphene-semiconductor heterojunction photodetectors, graphene based bolometers. It is also reported that there are several physical mechanisms enabling photodetection: photovoltaic effect, photo-thermoelectric effect, bolometric effect, photogating effect, and so on. In this work, we report a simple approach for the realization of graphene based resistive photo-detection devices and the measurements of their photoelectrical response. The graphene were synthesized directly on the glass substrate by novel growth method patented in our lab. Then, the metal electrodes were deposited by thermal evaporation on it, with an electrode length and width of 1.5 mm and 300 μm respectively, using Co to fabricate simple graphene based resistive photosensor. The measurements show that the graphene resistive devices exhibit a photoresponse to the illumination of visible light. The observed re-sistance response was reproducible and similar after many cycles of on and off operations. This photoelectrical response may be attributed not only to the direct photocurrent process but also to the desorption of oxygen. Our work shows that the simple graphene resistive devices have potential in photodetection applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=graphene" title="graphene">graphene</a>, <a href="https://publications.waset.org/abstracts/search?q=resistive%20sensor" title=" resistive sensor"> resistive sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=optoelectronics" title=" optoelectronics"> optoelectronics</a>, <a href="https://publications.waset.org/abstracts/search?q=photoresponse" title=" photoresponse"> photoresponse</a> </p> <a href="https://publications.waset.org/abstracts/25297/photo-electrical-response-in-graphene-based-resistive-sensor" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25297.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">286</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5004</span> Effector and Memory Immune Responses Induced by Total Extracts of Naegleria fowleri Co-Administered with Cholera Toxin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Q.%20B.%20Maria%20de%20la%20Luz%20Ortega%20Ju%C3%A1rez">Q. B. Maria de la Luz Ortega Juárez</a>, <a href="https://publications.waset.org/abstracts/search?q=Sa%C3%BAl%20Rojas%20Hern%C3%A1ndez"> Saúl Rojas Hernández</a>, <a href="https://publications.waset.org/abstracts/search?q=Itzel%20Berenice%20Rodr%C3%ADguez%20Mera"> Itzel Berenice Rodríguez Mera</a>, <a href="https://publications.waset.org/abstracts/search?q=Mar%C3%ADa%20Maricela%20Carrasco%20Y%C3%A9pez"> María Maricela Carrasco Yépez</a>, <a href="https://publications.waset.org/abstracts/search?q=Mara%20Gutierrez%20S%C3%A1nchez"> Mara Gutierrez Sánchez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Naegleria fowleri is a free-living amoeba found mainly in temperate freshwater and is the etiologic agent of primary amebic meningoencephalitis (PAM), a fatal acute disease with a mortality rate greater than 95%. At present, there are no treatments available for MAP, and the development of effective vaccines that generate long-term immunological memory allowing protection against MAP would be of great importance. The objective of this work was to analyze the effector and memory immune response in BALB/c mice immunized with total extract of N. fowleri co-administered with cholera toxin. In this study, BALB/c mice were immunized four times intranasally with ET of N. fowleri adjuvanted with CT with or without booster at three months and were challenged or not with the lethal dose of N. fowleri, determining survival, the humoral, effector and memory response, by ELISA and flow cytometry techniques. The results obtained showed that the survival of mice immunized with booster had 60% protection compared to the group without booster, which obtained 20% protection. Evaluating the humoral response, it was found that both IgG and IgA levels were higher in sera than in nasal washes in both treatments. In the cellular response, the increase in the percentage of positive cells was found for effector T and B lymphocytes in the nasal passages (NP) in the group with boost and nasopharynx-associated lymphoid tissue (NALT) in the group without boost and lymphocytes only. B in both treatments, as well as in memory cells treatment with boost T lymphocytes in PN and NALT and without boost in cervical lymph nodes (CG) with respect to B lymphocytes, in PN, GC and NALT in treatment with boost and NALT in treatment without booster. Therefore, the involvement of the effector immune response and memory play a fundamental role for protection against N. fowleri and for the development of vaccine candidates. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=immune%20response" title="immune response">immune response</a>, <a href="https://publications.waset.org/abstracts/search?q=immunological%20memory" title=" immunological memory"> immunological memory</a>, <a href="https://publications.waset.org/abstracts/search?q=naegleria%20fowleri" title=" naegleria fowleri"> naegleria fowleri</a>, <a href="https://publications.waset.org/abstracts/search?q=primary%20amebic%20meningoencephalitis" title=" primary amebic meningoencephalitis"> primary amebic meningoencephalitis</a> </p> <a href="https://publications.waset.org/abstracts/166460/effector-and-memory-immune-responses-induced-by-total-extracts-of-naegleria-fowleri-co-administered-with-cholera-toxin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166460.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5003</span> Towards a Biologically Relevant Tumor-on-a-Chip: Multiplex Microfluidic Platform to Study Breast Cancer Drug Response </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Soroosh%20Torabi">Soroosh Torabi</a>, <a href="https://publications.waset.org/abstracts/search?q=Brad%20Berron"> Brad Berron</a>, <a href="https://publications.waset.org/abstracts/search?q=Ren%20Xu"> Ren Xu</a>, <a href="https://publications.waset.org/abstracts/search?q=Christine%20Trinkle"> Christine Trinkle</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Microfluidics integrated with 3D cell culture is a powerful technology to mimic cellular environment, and can be used to study cell activities such as proliferation, migration and response to drugs. This technology has gained more attention in cancer studies over the past years, and many organ-on-a-chip systems have been developed to study cancer cell behaviors in an ex-vivo tumor microenvironment. However, there are still some barriers to adoption which include low throughput, complexity in 3D cell culture integration and limitations on non-optical analysis of cells. In this study, a user-friendly microfluidic multi-well plate was developed to mimic the in vivo tumor microenvironment. The microfluidic platform feeds multiple 3D cell culture sites at the same time which enhances the throughput of the system. The platform uses hydrophobic Cassie-Baxter surfaces created by microchannels to enable convenient loading of hydrogel/cell suspensions into the device, while providing barrier free placement of the hydrogel and cells adjacent to the fluidic path. The microchannels support convective flow and diffusion of nutrients to the cells and a removable lid is used to enable further chemical and physiological analysis on the cells. Different breast cancer cell lines were cultured in the device and then monitored to characterize nutrient delivery to the cells as well as cell invasion and proliferation. In addition, the drug response of breast cancer cell lines cultured in the device was compared to the response in xenograft models to the same drugs to analyze relevance of this platform for use in future drug-response studies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=microfluidics" title="microfluidics">microfluidics</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-well%203d%20cell%20culture" title=" multi-well 3d cell culture"> multi-well 3d cell culture</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20microenvironment" title=" tumor microenvironment"> tumor microenvironment</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor-on-a-chip" title=" tumor-on-a-chip"> tumor-on-a-chip</a> </p> <a href="https://publications.waset.org/abstracts/91076/towards-a-biologically-relevant-tumor-on-a-chip-multiplex-microfluidic-platform-to-study-breast-cancer-drug-response" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91076.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">264</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5002</span> Investigation of the Space in Response to the Conditions Caused by the Pandemics and Presenting Five-Scale Design Guidelines to Adapt and Prepare to Face the Pandemics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sara%20Ramezanzadeh">Sara Ramezanzadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Nashid%20Nabian"> Nashid Nabian</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Historically, pandemics in different periods have caused compulsory changes in human life. In the case of Covid-19, according to the limitations and established care instructions, spatial alignment with the conditions is important. Following the outbreak of Covid-19, the question raised in this study is how to do spatial design in five scales, namely object, space, architecture, city, and infrastructure, in response to the consequences created in the realms under study. From the beginning of the pandemic until now, some changes in the spatial realm have been created spontaneously or by space users. These transformations have been mostly applied in modifiable parts such as furniture arrangement, especially in work-related spaces. To implement other comprehensive requirements, flexibility and adaptation of space design to the conditions resulting from the pandemics are needed during and after the outbreak. Studying the effects of pandemics from the past to the present, this research covers eight major realms, including three categories of ramifications, solutions, and paradigm shifts, and analytical conclusions about the solutions that have been created in response to them. Finally, by the consideration of epidemiology as a modern discipline influencing the design, spatial solutions in the five scales mentioned (in response to the effects of the eight realms for spatial adaptation in the face of pandemics and their following conditions) are presented as a series of guidelines. Due to the unpredictability of possible pandemics in the future, the possibility of changing and updating the provided guidelines is considered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pandemics" title="pandemics">pandemics</a>, <a href="https://publications.waset.org/abstracts/search?q=Covid%2019" title=" Covid 19"> Covid 19</a>, <a href="https://publications.waset.org/abstracts/search?q=spatial%20design" title=" spatial design"> spatial design</a>, <a href="https://publications.waset.org/abstracts/search?q=ramifications" title=" ramifications"> ramifications</a>, <a href="https://publications.waset.org/abstracts/search?q=solutions" title=" solutions"> solutions</a>, <a href="https://publications.waset.org/abstracts/search?q=paradigm%20shifts" title=" paradigm shifts"> paradigm shifts</a>, <a href="https://publications.waset.org/abstracts/search?q=guidelines" title=" guidelines"> guidelines</a> </p> <a href="https://publications.waset.org/abstracts/159979/investigation-of-the-space-in-response-to-the-conditions-caused-by-the-pandemics-and-presenting-five-scale-design-guidelines-to-adapt-and-prepare-to-face-the-pandemics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159979.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">82</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5001</span> A Micro-Scale of Electromechanical System Micro-Sensor Resonator Based on UNO-Microcontroller for Low Magnetic Field Detection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Waddah%20Abdelbagi%20Talha">Waddah Abdelbagi Talha</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Abdullah%20Elmaleeh"> Mohammed Abdullah Elmaleeh</a>, <a href="https://publications.waset.org/abstracts/search?q=John%20Ojur%20Dennis"> John Ojur Dennis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper focuses on the simulation and implementation of a resonator micro-sensor for low magnetic field sensing based on a U-shaped cantilever and piezoresistive configuration, which works based on Lorentz force physical phenomena. The resonance frequency is an important parameter that depends upon the highest response and sensitivity through the frequency domain (frequency response) of any vibrated micro-scale of an electromechanical system (MEMS) device. And it is important to determine the direction of the detected magnetic field. The deflection of the cantilever is considered for vibrated mode with different frequencies in the range of (0 Hz to 7000 Hz); for the purpose of observing the frequency response. A simple electronic circuit-based polysilicon piezoresistors in Wheatstone's bridge configuration are used to transduce the response of the cantilever to electrical measurements at various voltages. Microcontroller-based Arduino program and PROTEUS electronic software are used to analyze the output signals from the sensor. The highest output voltage amplitude of about 4.7 mV is spotted at about 3 kHz of the frequency domain, indicating the highest sensitivity, which can be called resonant sensitivity. Based on the resonant frequency value, the mode of vibration is determined (up-down vibration), and based on that, the vector of the magnetic field is also determined. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=resonant%20frequency" title="resonant frequency">resonant frequency</a>, <a href="https://publications.waset.org/abstracts/search?q=sensitivity" title=" sensitivity"> sensitivity</a>, <a href="https://publications.waset.org/abstracts/search?q=Wheatstone%20bridge" title=" Wheatstone bridge"> Wheatstone bridge</a>, <a href="https://publications.waset.org/abstracts/search?q=UNO-microcontroller" title=" UNO-microcontroller"> UNO-microcontroller</a> </p> <a href="https://publications.waset.org/abstracts/152891/a-micro-scale-of-electromechanical-system-micro-sensor-resonator-based-on-uno-microcontroller-for-low-magnetic-field-detection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152891.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <ul class="pagination"> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=in-plane%20response&page=8" rel="prev">&lsaquo;</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=in-plane%20response&page=1">1</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=in-plane%20response&page=2">2</a></li> <li class="page-item disabled"><span class="page-link">...</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=in-plane%20response&page=6">6</a></li> <li class="page-item"><a class="page-link" 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