Nature Chemistry

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class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01659-x/MediaObjects/41557_2024_1659_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01659-x/MediaObjects/41557_2024_1659_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01659-x/MediaObjects/41557_2024_1659_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01659-x" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">The original caretakers of salvinorin A and recognizing Indigenous contributions to science</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Much natural-product-based drug discovery has depended on the practices of Indigenous Peoples, who have sometimes invested centuries of care into the cultivation and use of plant or fungal matter. However, the contributions of the original discoverers can be lost as the natural products are developed into pharmaceutical products.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Khalyd J. Clay</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Ryan A. Shenvi</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Comment</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-22" itemprop="datePublished">22 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01657-z/MediaObjects/41557_2024_1657_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01657-z/MediaObjects/41557_2024_1657_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01657-z/MediaObjects/41557_2024_1657_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01657-z" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">The chemical sciences need introverts too</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>About two thirds of western society are extroverts, but the contemplative nature of science means that this is not true of the academic population. Bruce Gibb discusses extraversion and introversion in science and asks whether the movement towards larger projects involving teams of scientists is making it harder for introverts and for disruptive discoveries.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Bruce C. 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This Review discusses hybrid glasses through the lens of crystalline metal–organic frameworks and glass chemistry, physics and engineering, providing a vision for the future of this class of materials.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Thomas D. Bennett</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Satoshi Horike</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Lothar Wondraczek</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Review Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-11" itemprop="datePublished">11 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01660-4/MediaObjects/41557_2024_1660_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01660-4/MediaObjects/41557_2024_1660_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01660-4/MediaObjects/41557_2024_1660_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01660-4" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Ubiquitin is a chemist’s playground</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Jakob Farnung and Brenda Schulman detail chemical diversification that endows the protein ubiquitin with many important cellular functions.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jakob Farnung</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Brenda A. 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Clay</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Ryan A. 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Houk</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xuefeng Guo</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Matters Arising</span></span><time class="c-meta__item" datetime="2024-09-23" itemprop="datePublished">23 Sept 2024</time> </div> </article> </div></li> </ul> </div> <div class="app-latest-issue-row__side"> <div class="app-latest-issue-row__image"> <picture> <source type="image/webp" srcset="https://media.springernature.com/w440/springer-static/cover-hires/journal/41557/16/11?as=webp&q=95"> <img src="https://media.springernature.com/w440/springer-static/cover-hires/journal/41557/16/11?q=95" alt="Volume 16 Issue 11" itemprop="image"> </picture> </div> <div class="app-latest-issue-row__buttons app-latest-issue-row--by-3"> <div class="app-latest-issue-row__button"> <a href="/nchem/current-issue" class="u-button u-button--full-width" data-track="click" data-track-action="view current issue" data-track-label="button">Contents</a> </div> <div class="app-latest-issue-row__button"> <a href="/nchem/volumes/16" class="u-button u-button--full-width" data-track="click" data-track-action="click view all issues">View all issues</a> </div> <div class="app-latest-issue-row__button"><a href="/nchem/subscribe" class="u-button u-button--primary u-button--full-width" data-track="click" data-track-action="subscribe" data-track-label="button">Subscribe</a></div> </div> </div> </div> </div> </section> <section id="announcement-content" class="u-mb-48 u-mt-24" data-track-component="announcement content grid"> <div class="u-container"> <div class="c-section-heading" data-test="title"> <h2 class="u-ma-0"> Announcements </h2> </div> <ul class="app-announcement-list-row"> <li class="app-announcement-list-row__item"> <article class="c-card c-card--flush u-pl-0 u-justify-content-space-between"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-d292e66397695661ed0bf9dd6dbff593.jpg?as=webp 160w, https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-d292e66397695661ed0bf9dd6dbff593.jpg?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img data-test="image-0" src="https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-d292e66397695661ed0bf9dd6dbff593.jpg" alt="A Nobel medal in the foreground with some beakers and flasks in the background." itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline" data-test="announcement-title-0"> <a href="https://www.nature.com/collections/edjcfdihdi" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="click on homepage featured announcement" data-track-label="announcement 0"> 2024 Nobel Prize in Chemistry </a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description" data-test="description-0"> <p>The 2024 Nobel Prize in Chemistry has been awarded to David Baker “for computational protein design” and to Demis Hassabis and John M. Jumper “for protein structure prediction”. Proteins are life's essential building blocks, nature's most ingenious molecular machines and the basis of all living organisms.</p> </div> </div> </div> </article> </li> <li class="app-announcement-list-row__item"> <article class="c-card c-card--flush u-pl-0 u-justify-content-space-between"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-0d9d2e21e504a399e090afb4f023aad2.jpg?as=webp 160w, https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-0d9d2e21e504a399e090afb4f023aad2.jpg?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img data-test="image-1" src="https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-0d9d2e21e504a399e090afb4f023aad2.jpg" alt="artistic impression of" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline" data-test="announcement-title-1"> <a href="https://www.nature.com/collections/ejdedgbggi" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="click on homepage featured announcement" data-track-label="announcement 1"> Focus on phase separation </a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description" data-test="description-1"> <p>A collection of Articles with associated content and a Q&A describes a selection of factors that influence biomolecular phase separation. They explore advances in methodologies for studying this phenomenon in cells and insight into what the key next steps are for the field.</p> </div> </div> </div> </article> </li> <li class="app-announcement-list-row__item"> <article class="c-card c-card--flush u-pl-0 u-justify-content-space-between"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-39288d7e1a0e98777bef71f5b8db9418.png?as=webp 160w, https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-39288d7e1a0e98777bef71f5b8db9418.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img data-test="image-2" src="https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/5937/announcement-image-39288d7e1a0e98777bef71f5b8db9418.png" alt="A petrochemical refinery located at the edge of a body of water illuminates the surroundings with its many bright lights at night" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline" data-test="announcement-title-2"> <a href="https://www.nature.com/natchemeng/" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="click on homepage featured announcement" data-track-label="announcement 2"> <i>Nature Chemical Engineering</i> open for submissions </a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description" data-test="description-2"> <p><i>Nature Chemical Engineering</i> is open for submissions. 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Now, a bulky hydrindacene ligand has been used to stabilize a triplet arylnitrene synthesized through photolysis of an azide precursor under mild conditions. The triplet nitrene has been fully characterized by various techniques including single-crystal X-ray diffraction, electron paramagnetic resonance spectroscopy and theoretical calculations.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Dongmin Wang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wang Chen</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Gengwen Tan</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-19" itemprop="datePublished">19 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01673-z/MediaObjects/41557_2024_1673_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01673-z/MediaObjects/41557_2024_1673_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01673-z/MediaObjects/41557_2024_1673_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01673-z" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Dynamic amine sorting enables multiselective construction of unsymmetrical chiral diamines</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Efficient strategies to differentiate and sort congeneric compounds are lacking. Now a metal-mediated dynamic amine-sorting strategy has been developed to precisely differentiate and assemble different amine congeners in an orderly manner, facilitating highly chemo-, regio- and enantioselective aminomethylamination of dienes for the construction of unsymmetrical chiral diamines.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Shoule Cai</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zeyu Zhao</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hanmin Huang</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-18" itemprop="datePublished">18 Nov 2024</time> </div> </article> </div> </li> </ul> </div> </section> <section id="latest-reviews" class="u-mb-48" data-track-component="latest reviews grid"> <div class="u-container"> <div class="c-section-heading"> <h2 class="u-ma-0"> <a href="/nchem/reviews-and-analysis" class="c-section-heading__link" data-track="click" data-track-action="view all" data-track-label="button"> Latest Reviews & Analysis <svg class="c-section-heading__icon" aria-hidden="true" focusable="false" height="16" width="16"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-chevron-right"></use></svg> </a> </h2> </div> <ul class="u-list-reset app-reviews-row"> <li class="app-reviews-row__main"> <ul class="app-reviews-row__grid"> <li class="app-reviews-row__item app-reviews-row__item--major"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush c-card--major" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01677-9/MediaObjects/41557_2024_1677_Fig1_HTML.png?as=webp 290w, https://media.springernature.com/w485h264/springer-static/image/art%3A10.1038%2Fs41557-024-01677-9/MediaObjects/41557_2024_1677_Fig1_HTML.png?as=webp 485w" sizes=" (max-width: 768px) 290px, (max-width: 1200px) 485px, 485px"> <img src="https://media.springernature.com/w485h264/springer-static/image/art%3A10.1038%2Fs41557-024-01677-9/MediaObjects/41557_2024_1677_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01677-9" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Mimicking fluorophores from nature to generate artificial fluorescent proteins and biosensors</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16" itemprop="description"> <p>The miniaturization and redesigning of proteins to bear fluorescence signals can broaden their scope for potential applications. Now, one can construct a range of compact artificial fluorescent proteins and develop protein biosensors by genetically encoding a natural fluorescent protein chromophore analogue.</p> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Chia-Heng Hsiung</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xin Zhang</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item" datetime="2024-11-28" itemprop="datePublished">28 Nov 2024</time> </div> </div> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01674-y/MediaObjects/41557_2024_1674_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01674-y/MediaObjects/41557_2024_1674_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01674-y/MediaObjects/41557_2024_1674_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01674-y" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Cyclic amine ring expansion</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Aza-heterocycles with rings of more than 6 members are underrepresented in medicinal chemistry owing to challenges with their synthesis. Now, the conversion of 5- and 6-membered saturated cyclic amines into 7- and 8-membered aza-heterocycles can be achieved via a ring expansion cascade reaction.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jack M. Wootton</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">William P. Unsworth</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item" datetime="2024-11-21" itemprop="datePublished">21 Nov 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01676-w/MediaObjects/41557_2024_1676_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01676-w/MediaObjects/41557_2024_1676_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01676-w/MediaObjects/41557_2024_1676_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01676-w" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Catalysis-enabled amine sorting</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Multicomponent couplings offer powerful approaches for rapidly increasing molecular complexity, but typically require functionally distinct reagents. Now, through dynamic combinatorial chemistry, structurally similar amino groups can be efficiently differentiated, enabling the enantioselective aminomethylamination of dienes to prepare 1,3-diamines.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Steven J. Malcolmson</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item" datetime="2024-11-18" itemprop="datePublished">18 Nov 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01661-3/MediaObjects/41557_2024_1661_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01661-3/MediaObjects/41557_2024_1661_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01661-3/MediaObjects/41557_2024_1661_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01661-3" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Supramolecular crystals for hydrogen storage</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Adsorbents for efficient hydrogen storage require both a high gravimetric and volumetric storage capacity. A catenation strategy guided by hydrogen bonding is now demonstrated for the construction of supramolecular crystals with both high volumetric and large gravimetric surface areas, robustness and ideal pore diameters, which contribute to their good performance for hydrogen storage.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Research Briefing</span></span><time class="c-meta__item" datetime="2024-10-23" itemprop="datePublished">23 Oct 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01655-1/MediaObjects/41557_2024_1655_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01655-1/MediaObjects/41557_2024_1655_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01655-1/MediaObjects/41557_2024_1655_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01655-1" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Properties governing small-molecule partitioning into biomolecular condensates</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Membraneless cellular assemblies termed biomolecular condensates — into which diverse biopolymers partition — mediate myriad biological processes. A study now reveals that physicochemical features, not specific stereochemistry, influence whether small molecules are enriched within or excluded from a diverse panel of condensates.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Bappaditya Chandra</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Swarnendu Tripathi</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Richard Kriwacki</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item" datetime="2024-10-22" itemprop="datePublished">22 Oct 2024</time> </div> </article> </div> </li> </ul> </li> <li> <ul class="app-reviews-row__side"> <li class="app-reviews-row__side-item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01641-7" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Fullerenes promote transition-metal-catalysed ammonia synthesis</a> </h3> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">A. 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Integrating energy justice into the curricula and research of those who aim to fix this crisis is essential to equip students with the expertise needed to create and implement equitable energy solutions.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Casey M. Davis</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Lacey S. Roberts</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Michael F. 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Schulman</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">In Your Element</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-31" itemprop="datePublished">31 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01657-z/MediaObjects/41557_2024_1657_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01657-z/MediaObjects/41557_2024_1657_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01657-z/MediaObjects/41557_2024_1657_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01657-z" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">The chemical sciences need introverts too</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>About two thirds of western society are extroverts, but the contemplative nature of science means that this is not true of the academic population. Bruce Gibb discusses extraversion and introversion in science and asks whether the movement towards larger projects involving teams of scientists is making it harder for introverts and for disruptive discoveries.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Bruce C. Gibb</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Thesis</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-23" itemprop="datePublished">23 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41557-024-01659-x/MediaObjects/41557_2024_1659_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01659-x/MediaObjects/41557_2024_1659_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41557-024-01659-x/MediaObjects/41557_2024_1659_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41557-024-01659-x" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">The original caretakers of salvinorin A and recognizing Indigenous contributions to science</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Much natural-product-based drug discovery has depended on the practices of Indigenous Peoples, who have sometimes invested centuries of care into the cultivation and use of plant or fungal matter. However, the contributions of the original discoverers can be lost as the natural products are developed into pharmaceutical products.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Khalyd J. Clay</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Ryan A. 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Radiology has opened a broad area search in translational medical imaging. This position is full time at t...</p> <p class="u-ma-0 u-mt-8">Palo Alto, California</p> <p class="u-ma-0 u-mt-8">Stanford Medicine Radiology</p> </div> </div> <div class="u-hide u-show-at-sm" style="max-width: 150px;"> <img src="https://www.nature.com/naturecareers/getasset/af4f99ed-b574-46da-984f-0745999aab2b/" alt="" class="u-ml-8" loading="lazy"> </div> </li> <li class="c-list-group__item u-display-flex"> <div class="u-display-flex u-flex-direction-column"> <h4 class="u-mb-8 u-mt-0"><a href="https://www.nature.com/naturecareers/job/12832526/postdoctoral-researcher/?TrackID=3453&utm_source=widget&utm_medium=referral&utm_campaign=3453" class="u-link-inherit" data-track="click" data-track-action="Rank:(3)" data-track-category="job-list" data-track-label="12832526">Postdoctoral Researcher</a></h4> <div class="u-mt-auto c-meta"> <p class="u-ma-0">Postdoctoral researcher will develop electrochemical energy storage and conversion system based on material development and advanced 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