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Disponible en 24 idiomas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-24" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">24 idiomas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AB%D9%86%D8%A7%D8%A6%D9%8A_%D9%87%D9%8A%D8%AF%D8%B1%D9%88%D9%83%D9%88%D8%AF%D8%A7%D9%8A%D9%8A%D9%86" title="ثنائي هيدروكودايين – árabe" lang="ar" hreflang="ar" data-title="ثنائي هيدروكودايين" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%AF%DB%8C_%D9%87%DB%8C%D8%AF%D8%B1%D9%88%DA%A9%D9%88%D8%AF%DB%8C%D9%86" title="دی هیدروکودین – South Azerbaijani" lang="azb" hreflang="azb" data-title="دی هیدروکودین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Dihydrokodein" title="Dihydrokodein – checo" lang="cs" hreflang="cs" data-title="Dihydrokodein" data-language-autonym="Čeština" data-language-local-name="checo" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Deuhydrocodein" title="Deuhydrocodein – galés" lang="cy" hreflang="cy" data-title="Deuhydrocodein" data-language-autonym="Cymraeg" data-language-local-name="galés" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Dihydrocodein" title="Dihydrocodein – alemán" lang="de" hreflang="de" data-title="Dihydrocodein" data-language-autonym="Deutsch" data-language-local-name="alemán" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Dihydrocodeine" title="Dihydrocodeine – inglés" lang="en" hreflang="en" data-title="Dihydrocodeine" data-language-autonym="English" data-language-local-name="inglés" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AF%DB%8C%E2%80%8C%D9%87%DB%8C%D8%AF%D8%B1%D9%88%DA%A9%D8%AF%D8%A6%DB%8C%D9%86" title="دی‌هیدروکدئین – persa" lang="fa" hreflang="fa" data-title="دی‌هیدروکدئین" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Dihydrokodeiini" title="Dihydrokodeiini – finés" lang="fi" hreflang="fi" data-title="Dihydrokodeiini" data-language-autonym="Suomi" data-language-local-name="finés" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Dihydrocod%C3%A9ine" title="Dihydrocodéine – francés" lang="fr" hreflang="fr" data-title="Dihydrocodéine" data-language-autonym="Français" data-language-local-name="francés" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Dihidrokodein" title="Dihidrokodein – croata" lang="hr" hreflang="hr" data-title="Dihidrokodein" data-language-autonym="Hrvatski" data-language-local-name="croata" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Dihidrokodein" title="Dihidrokodein – húngaro" lang="hu" hreflang="hu" data-title="Dihidrokodein" data-language-autonym="Magyar" data-language-local-name="húngaro" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Diidrocodeina" title="Diidrocodeina – italiano" lang="it" hreflang="it" data-title="Diidrocodeina" data-language-autonym="Italiano" data-language-local-name="italiano" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%B8%E3%83%92%E3%83%89%E3%83%AD%E3%82%B3%E3%83%87%E3%82%A4%E3%83%B3" title="ジヒドロコデイン – japonés" lang="ja" hreflang="ja" data-title="ジヒドロコデイン" data-language-autonym="日本語" data-language-local-name="japonés" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EB%8B%A4%EC%9D%B4%ED%95%98%EC%9D%B4%EB%93%9C%EB%A1%9C%EC%BD%94%EB%8D%B0%EC%9D%B8" title="다이하이드로코데인 – coreano" lang="ko" hreflang="ko" data-title="다이하이드로코데인" data-language-autonym="한국어" data-language-local-name="coreano" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Dihydrocode%C3%AFne" title="Dihydrocodeïne – neerlandés" lang="nl" hreflang="nl" data-title="Dihydrocodeïne" data-language-autonym="Nederlands" data-language-local-name="neerlandés" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Dihydrokodeina" title="Dihydrokodeina – polaco" lang="pl" hreflang="pl" data-title="Dihydrokodeina" data-language-autonym="Polski" data-language-local-name="polaco" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Di-hidrocode%C3%ADna" title="Di-hidrocodeína – portugués" lang="pt" hreflang="pt" data-title="Di-hidrocodeína" data-language-autonym="Português" data-language-local-name="portugués" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Dihidrocodein%C4%83" title="Dihidrocodeină – rumano" lang="ro" hreflang="ro" data-title="Dihidrocodeină" data-language-autonym="Română" data-language-local-name="rumano" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%94%D0%B8%D0%B3%D0%B8%D0%B4%D1%80%D0%BE%D0%BA%D0%BE%D0%B4%D0%B5%D0%B8%D0%BD" title="Дигидрокодеин – ruso" lang="ru" hreflang="ru" data-title="Дигидрокодеин" data-language-autonym="Русский" data-language-local-name="ruso" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Dihidrokodein" title="Dihidrokodein – serbocroata" lang="sh" hreflang="sh" data-title="Dihidrokodein" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbocroata" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Dihidrokodein" title="Dihidrokodein – serbio" lang="sr" hreflang="sr" data-title="Dihidrokodein" data-language-autonym="Српски / srpski" data-language-local-name="serbio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Dihydrokodein" title="Dihydrokodein – sueco" lang="sv" hreflang="sv" data-title="Dihydrokodein" data-language-autonym="Svenska" data-language-local-name="sueco" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B9%84%E0%B8%94%E0%B9%84%E0%B8%AE%E0%B9%82%E0%B8%94%E0%B8%A3%E0%B9%82%E0%B8%84%E0%B8%94%E0%B8%B5%E0%B8%AD%E0%B8%B5%E0%B8%99" title="ไดไฮโดรโคดีอีน – tailandés" lang="th" hreflang="th" data-title="ไดไฮโดรโคดีอีน" data-language-autonym="ไทย" data-language-local-name="tailandés" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a 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img{max-width:100%;height:auto}.mw-parser-output .infobox .mw-kartographer-container .thumbinner,.mw-parser-output .infobox .mw-kartographer-map{box-sizing:border-box;width:100%!important}body.skin-timeless .mw-parser-output .infobox .imagen a.image>img{max-width:100%!important;height:auto!important}</style><table class="infobox" style="width:22.7em; line-height: 1.4em; text-align:left; padding:.23em;"><tbody><tr><th colspan="3" class="cabecera medicina" style="text-align:center;background-color:transparent;color:inherit;">Dihidrocodeína</th></tr><tr><td colspan="3" class="imagen" style="text-align:center;background:#eee;;"> <span typeof="mw:File"><a href="/wiki/Archivo:Dihydrocodeine_skeletal.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/9/97/Dihydrocodeine_skeletal.svg/220px-Dihydrocodeine_skeletal.svg.png" decoding="async" width="220" height="201" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/97/Dihydrocodeine_skeletal.svg/330px-Dihydrocodeine_skeletal.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/97/Dihydrocodeine_skeletal.svg/440px-Dihydrocodeine_skeletal.svg.png 2x" data-file-width="460" data-file-height="420" /></a></span></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Nombre (<a href="/wiki/Uni%C3%B3n_Internacional_de_Qu%C3%ADmica_Pura_y_Aplicada" title="Unión Internacional de Química Pura y Aplicada">IUPAC</a>) sistemático</th></tr><tr><td colspan="3" style="text-align:center;style="> <small>4,5-alfa-epoxi-3-metoxi-17-metil-morfinan-6-ol</small></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Identificadores</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/N%C3%BAmero_de_registro_CAS" title="Número de registro CAS">Número CAS</a></th><td colspan="2" style="background:#eee;;"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://webbook.nist.gov/cgi/cbook.cgi?ID=125-28-0&Units=SI">125-28-0</a></span></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/C%C3%B3digo_ATC" title="Código ATC">Código ATC</a></th><td colspan="2" style="background:#eee;;"> <a href="/wiki/Anexo:C%C3%B3digo_ATC_N02" title="Anexo:Código ATC N02">N02</a><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.whocc.no/atc_ddd_index/?code=N02AA08">AA08</a></span> <a href="/wiki/Anexo:C%C3%B3digo_ATC_N02" title="Anexo:Código ATC N02">N02</a><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.whocc.no/atc_ddd_index/?code=N02AA58">AA58</a></span></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/PubChem" title="PubChem">PubChem</a></th><td colspan="2" style="background:#eee;;"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6426647">6426647</a></span></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Datos químicos</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/F%C3%B3rmula_molecular" title="Fórmula molecular">Fórmula</a></th><td colspan="2" style="background:#eee;;"> <a href="/wiki/Carbono" title="Carbono"><span style="color: rgb(000,000,000); font-weight: bold;">C</span></a><sub>18</sub><a href="/wiki/Hidr%C3%B3geno" title="Hidrógeno"><span style="color: rgb(154,154,154); font-weight: bold;">H</span></a><sub>23</sub><a href="/wiki/Nitr%C3%B3geno" title="Nitrógeno"><span style="color: rgb(000,000,255); font-weight: bold;">N</span></a><a href="/wiki/Ox%C3%ADgeno" title="Oxígeno"><span style="color: rgb(232,070,070); font-weight: bold;">O</span></a><sub>3</sub><sup> </sup></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Masa_molar" title="Masa molar">Peso mol.</a></th><td colspan="2" style="background:#eee;;"> 301.38 <a href="/wiki/Gramo" title="Gramo">g</a>/<a href="/wiki/Mol_(unidad)" class="mw-redirect" title="Mol (unidad)">mol</a></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Farmacocinética</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Biodisponibilidad" title="Biodisponibilidad">Biodisponibilidad</a></th><td colspan="2" style="background:#eee;;"> 20% (oral)<sup id="cite_ref-EurJClinPharmacol1983-Rowell_1-0" class="reference separada"><a href="#cite_note-EurJClinPharmacol1983-Rowell-1"><span class="corchete-llamada">[</span>1<span class="corchete-llamada">]</span></a></sup></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Metabolismo_de_f%C3%A1rmacos" title="Metabolismo de fármacos">Metabolismo</a></th><td colspan="2" style="background:#eee;;"> <a href="/wiki/H%C3%ADgado" title="Hígado">Hígado</a> (<a href="/wiki/CYP3A4" title="CYP3A4">CYP3A4</a> y <a href="/wiki/CYP2D6" title="CYP2D6">CYP2D6</a>)</td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Semivida_de_eliminaci%C3%B3n" title="Semivida de eliminación">Vida media</a></th><td colspan="2" style="background:#eee;;"> 4 horas<sup id="cite_ref-EurJClinPharmacol1983-Rowell_1-1" class="reference separada"><a href="#cite_note-EurJClinPharmacol1983-Rowell-1"><span class="corchete-llamada">[</span>1<span class="corchete-llamada">]</span></a></sup></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Datos clínicos</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Categor%C3%ADas_farmacol%C3%B3gicas_en_el_embarazo" title="Categorías farmacológicas en el embarazo">Cat. embarazo</a></th><td colspan="2" style="background:#eee;;"> C</td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;">Estado legal</th><td colspan="2" style="background:#eee;;"> solo Rx <small>(<a href="/wiki/Estados_Unidos" title="Estados Unidos">U.S.</a>)</small></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/V%C3%ADas_de_administraci%C3%B3n_de_f%C3%A1rmacos" title="Vías de administración de fármacos">Vías de adm.</a></th><td colspan="2" style="background:#eee;;"> oral, subcutánea, IM, rectal</td></tr><tr><td class="noprint" colspan="3" style="text-align:left;"><div class="plainlinks wikidata-link" style="font-size: 0.85em">[<a href="https://www.wikidata.org/wiki/Q377270" class="extiw" title="d:Q377270">editar datos en Wikidata</a>]</div></td></tr></tbody></table> <p><b>Dihidrocodeína</b> es el <a href="/wiki/Medicamento_gen%C3%A9rico" title="Medicamento genérico">nombre genérico</a> de un <a href="/wiki/Medicamento" title="Medicamento">medicamento</a> que actúa como <a href="/wiki/Analg%C3%A9sico" title="Analgésico">analgésico</a> para el rápido alivio del <a href="/wiki/Dolor" title="Dolor">dolor</a> moderado a grave<sup id="cite_ref-2" class="reference separada"><a href="#cite_note-2"><span class="corchete-llamada">[</span>2<span class="corchete-llamada">]</span></a></sup> y <a href="/wiki/Antitus%C3%ADgeno" title="Antitusígeno">antitusígeno</a>.<sup id="cite_ref-3" class="reference separada"><a href="#cite_note-3"><span class="corchete-llamada">[</span>3<span class="corchete-llamada">]</span></a></sup> La dihidrocodeína es un <a href="/wiki/Narc%C3%B3tico" title="Narcótico">narcótico</a> que pertenece al grupo de los <a href="/wiki/Opioide" title="Opioide">opioides</a>, por lo que provoca dependencia en los usuarios de larga data. </p><p>La dihidrocodeína tiene los mismos efectos que dos tabletas de otro narcótico llamado <a href="/wiki/Hidrocodona" title="Hidrocodona">hidrocodona</a> (<i>hydrocodone</i>, en inglés). El <b>dicodin</b> es un narcótico superior, comparado con el <b>vicodin</b>. </p><p>La dihidrocodeína también puede ser usada para otros propósitos diferentes a los especificados, incluso se estudia entre las drogas de abuso para evaluación de las unidades de conductas adictivas en un área sanitaria.<sup id="cite_ref-4" class="reference separada"><a href="#cite_note-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup> </p><p>Se ha afirmado que la actividad analgésica de la dihidrocodeína, se atribuye a su metabolito <a href="/wiki/Dihidromorfina" title="Dihidromorfina">dihidromorfina</a>. Esta afirmación se basa en que la dihidromorfina tiene una afinidad de unión a los receptores μ similares a la de la morfina y que posee aproximadamente 100 veces la actividad de la dihidrocodeína. Menos del 10% de DHC es metabolizado por O -desmetilación a dihidromorfina en el hombre. Los resultados de los estudios sugieren que el efecto analgésico después de la ingestión de dihidrocodeína se atribuye principalmente a la droga madre y no a su metabolito dihidromorfina. Por lo tanto, se puede deducir que las diferencias polimórficas en el metabolismo de dihidrocodeína a dihidromorfina tienen poco o ningún impacto sobre el efecto analgésico.<sup id="cite_ref-:_5-0" class="reference separada"><a href="#cite_note-:-5"><span class="corchete-llamada">[</span>5<span class="corchete-llamada">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Véase_también"><span id="V.C3.A9ase_tambi.C3.A9n"></span>Véase también</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dihidrocode%C3%ADna&action=edit&section=1" title="Editar sección: Véase también"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Opio" title="Opio">Opio</a></li> <li><a href="/wiki/C%C3%B3digo_ATC_N02" class="mw-redirect" title="Código ATC N02">Código ATC N02</a> (Fármacos activos sobre el sistema nervioso con propiedades analgésicas)</li> <li><a href="/wiki/Escalera_analg%C3%A9sica_de_la_OMS" title="Escalera analgésica de la OMS">Escalera analgésica de la OMS</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Referencias">Referencias</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dihidrocode%C3%ADna&action=edit&section=2" title="Editar sección: Referencias"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="listaref" style="list-style-type: decimal;"><ol class="references"> <li id="cite_note-EurJClinPharmacol1983-Rowell-1"><span class="mw-cite-backlink">↑ <a href="#cite_ref-EurJClinPharmacol1983-Rowell_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-EurJClinPharmacol1983-Rowell_1-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><span id="CITAREFRowell_F,_Seymour_R,_Rawlins_M1983" class="citation publicación">Rowell F, Seymour R, Rawlins M (1983). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_european-journal-of-clinical-pharmacology_1983-09_25_3/page/419">«Pharmacokinetics of intravenous and oral dihydrocodeine and its acid metabolites»</a>. <i>Eur J Clin Pharmacol</i> <b>25</b> (3): 419-24. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/6628531">6628531</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007%2FBF01037958">10.1007/BF01037958</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ADihidrocode%C3%ADna&rft.atitle=Pharmacokinetics+of+intravenous+and+oral+dihydrocodeine+and+its+acid+metabolites&rft.au=Rowell+F%2C+Seymour+R%2C+Rawlins+M&rft.aulast=Rowell+F%2C+Seymour+R%2C+Rawlins+M&rft.date=1983&rft.genre=article&rft.issue=3&rft.jtitle=Eur+J+Clin+Pharmacol&rft.pages=419-24&rft.volume=25&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_european-journal-of-clinical-pharmacology_1983-09_25_3%2Fpage%2F419&rft_id=info%3Adoi%2F10.1007%2FBF01037958&rft_id=info%3Apmid%2F6628531&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text">López-Correa, T. et al. <a rel="nofollow" class="external text" href="http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1134-80462006000600006&lng=es&nrm=iso">Lamotrigina en el dolor neuropático: revisión bibliográfica</a> (en español). <i>Rev. Soc. Esp. Dolor</i> [online]. 2006, vol. 13, n. 6 [citado 2010-01-19], pp. 410-420. ISSN 1134-8046.</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text">Martínez, E. et al. <a rel="nofollow" class="external text" href="http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1137-66272004000600009&lng=es&nrm=iso">Urgencias respiratorias</a> (en español). <i>Anales Sis San Navarra</i> [online]. 2004, vol. 27, suppl. 3 [citado 2010-01-22], pp. 87-97. ISSN 1137-6627.</span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text">Andrés, J. M. et al. <a rel="nofollow" class="external text" href="http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0034-79732002000200005&lng=es&nrm=iso">Drogas de abuso: evaluación de las unidades de conductas adictivas en un área sanitaria</a> (en español). <i>Rev Diagn Biol</i> [online]. 2002, vol. 51, n. 2 [citado 2010-01-22], pp. 63-68. ISSN 0034-7973.</span> </li> <li id="cite_note-:-5"><span class="mw-cite-backlink"><a href="#cite_ref-:_5-0">↑</a></span> <span class="reference-text"><span id="CITAREFWebb2001" class="citation publicación">Webb, James A; Amin Rostami-Hodjegan, Roslina Abdul-Manap, Ute Hofmann, Gerd Mikus, Farhad Kamali (2001). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_british-journal-of-clinical-pharmacology_2001-07_52_1/page/35">«Contribution of dihydrocodeine and dihydromorphine to analgesia following dihydrocodeine administration in man: a PK–PD modelling analysis»</a>. <i>Br J Clin Pharmacol.</i> <b>52</b> (1): 35. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1046%2Fj.0306-5251.2001.01414.x">10.1046/j.0306-5251.2001.01414.x</a></small><span class="reference-accessdate">. Consultado el 3 de diciembre de 2012</span>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ADihidrocode%C3%ADna&rft.atitle=Contribution+of+dihydrocodeine+and+dihydromorphine+to+analgesia+following+dihydrocodeine+administration+in+man%3A+a+PK%E2%80%93PD+modelling+analysis&rft.au=Webb%2C+James+A&rft.aufirst=James+A&rft.aulast=Webb&rft.date=2001&rft.genre=article&rft.issue=1&rft.jtitle=Br+J+Clin+Pharmacol.&rft.pages=35&rft.volume=52&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_british-journal-of-clinical-pharmacology_2001-07_52_1%2Fpage%2F35&rft_id=info%3Adoi%2F10.1046%2Fj.0306-5251.2001.01414.x&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span> <span style="display:none;font-size:100%" class="error citation-comment">La referencia utiliza el parámetro obsoleto <code>|coautores=</code> (<a href="/wiki/Ayuda:Errores_en_las_referencias#deprecated_params" title="Ayuda:Errores en las 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autoridades</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><b>Proyectos Wikimedia</b></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikidata" title="Wikidata"><img alt="Wd" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/20px-Wikidata-logo.svg.png" decoding="async" width="20" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/30px-Wikidata-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/40px-Wikidata-logo.svg.png 2x" data-file-width="1050" data-file-height="590" /></a></span> Datos:</span> <span class="uid"><a href="https://www.wikidata.org/wiki/Q377270" class="extiw" title="wikidata:Q377270">Q377270</a></span></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikimedia_Commons" title="Commonscat"><img alt="Commonscat" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> Multimedia:</span> <span class="uid"><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Dihydrocodeine">Dihydrocodeine</a></span> / <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Special:MediaSearch?type=image&search=%22Q377270%22">Q377270</a></span></span></li></ul> <hr /> <ul><li><b>Identificadores médicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=C014481">C014481</a></span></li> <li><span style="white-space:nowrap;">UMLS:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://web.archive.org/web/https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0058056">C0058056</a></span></li> <li><b>Identificadores químicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/N%C3%BAmero_CAS" class="mw-redirect" title="Número CAS">Número CAS</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=125-28-0">125-28-0</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/EINECS" class="mw-redirect" title="EINECS">Números EINECS</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://echa.europa.eu/information-on-chemicals/ec-inventory/-/dislist/details/204-732-3">204-732-3</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/C%C3%B3digo_ATC" title="Código ATC">Código ATC</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=N02AA08">N02AA08</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135276">135276</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1595/">CHEMBL1595</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.4447600.html">4447600</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://go.drugbank.com/drugs/DB01551">DB01551</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/PubChem" title="PubChem">PubChem</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/5284543">5284543</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Unique_Ingredient_Identifier" class="mw-redirect" title="Unique Ingredient Identifier">UNII</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://gsrs.ncats.nih.gov/ginas/app/beta/substances/N9I9HDB855">N9I9HDB855</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/KEGG" title="KEGG">KEGG</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D01481">D01481</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/SMILES" title="SMILES">SMILES</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.simolecule.com/cdkdepict/depict/bow/svg?smi=CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(CC4)O&zoom=2.0&annotate=cip">ID</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=1S/C18H23NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-13,17,20H,4-5,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1">ID</a></span></li> <li><span style="white-space:nowrap;">InChI key:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22RBOXVHNMENFORY-DNJOTXNNSA-N%22%5BInChIKey%5D">ID</a></span></li> <li><b>Identificadores biológicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=125-28-0">125-28-0</a></span></li></ul> </div></td></tr></tbody></table></div><div class="mw-mf-linked-projects hlist"> <ul><li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikidata" title="Wikidata"><img alt="Wd" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/20px-Wikidata-logo.svg.png" decoding="async" width="20" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/30px-Wikidata-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/40px-Wikidata-logo.svg.png 2x" data-file-width="1050" data-file-height="590" /></a></span> Datos:</span> <span class="uid"><a href="https://www.wikidata.org/wiki/Q377270" class="extiw" title="wikidata:Q377270">Q377270</a></span></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikimedia_Commons" title="Commonscat"><img alt="Commonscat" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> Multimedia:</span> <span class="uid"><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Dihydrocodeine">Dihydrocodeine</a></span> / <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Special:MediaSearch?type=image&search=%22Q377270%22">Q377270</a></span></span></li></ul> </div></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Obtenido de «<a dir="ltr" href="https://es.wikipedia.org/w/index.php?title=Dihidrocodeína&oldid=164047892">https://es.wikipedia.org/w/index.php?title=Dihidrocodeína&oldid=164047892</a>»</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Especial:Categor%C3%ADas" title="Especial:Categorías">Categorías</a>: <ul><li><a href="/wiki/Categor%C3%ADa:C%C3%B3digo_ATC_N" 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