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<!doctype html><html><head><title>View article</title><meta http-equiv="Content-Type" content="text/html;charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="referrer" content="always"><meta name="viewport" content="width=device-width,initial-scale=1,minimum-scale=1,maximum-scale=2"><meta name="format-detection" content="telephone=no"><link rel="shortcut icon" href="/favicon.ico"><meta name="description" content="‪CJL Murray, T Vos, R Lozano, M Naghavi, AD Flaxman, C Michaud, M Ezzati, K Shibuya, JA Salomon, S Abdalla…‬, ‪The lancet, 2012‬ - ‪Cited by 11,589‬"><meta property="og:description" content="‪CJL Murray, T Vos, R Lozano, M Naghavi, AD Flaxman, C Michaud, M Ezzati, K Shibuya, JA Salomon, S Abdalla…‬, ‪The lancet, 2012‬ - ‪Cited by 11,589‬"><meta property="og:title" content="‪Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010‬"><meta 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data-edit-link="/citations?view_op=edit_citation&hl=en&user=TGLiv1UAAAAJ&citation_for_view=TGLiv1UAAAAJ:w0odbtu79TwC&citation_for_view=TGLiv1UAAAAJ:w0odbtu79TwC&back_view_op=view_citation"><form method="post" id="gsc_vcpb_btns" action="/citations?view_op=view_citation&hl=en"><input type="hidden" name="xsrf" value="ADIE8skAAAAAZ0OOaU_bDp8E5yLfxYG-XcEl1Uo"><input type="hidden" name="s" value="TGLiv1UAAAAJ:w0odbtu79TwC"><input type="hidden" name="continue" value="/citations?view_op=list_works&hl=en&hl=en&user=TGLiv1UAAAAJ"></form><div id="gsc_oci_title_wrapper"><div id="gsc_oci_title_gg"><div class="gsc_oci_title_ggi"><a href="https://academiccommons.columbia.edu/doi/10.7916/883a-b398/download" data-clk="hl=en&sa=T&ei=6TxCZ6XLG_O_y9YPm4_bqAY"><span class='gsc_vcd_title_ggt'>[PDF]</span> from columbia.edu</a></div></div><div id="gsc_oci_title"><a class="gsc_oci_title_link" href="https://www.thelancet.com/article/S0140-6736(12)61689-4/abstract" data-clk="hl=en&sa=T&ei=6TxCZ6XLG_O_y9YPm4_bqAY">Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010</a></div></div><div id="gsc_oci_table"><div class="gs_scl"><div class="gsc_oci_field">Authors</div><div class="gsc_oci_value">Christopher JL Murray, Theo Vos, Rafael Lozano, Mohsen Naghavi, Abraham D Flaxman, Catherine Michaud, Majid Ezzati, Kenji Shibuya, Joshua A Salomon, Safa Abdalla, Victor Aboyans, Jerry Abraham, Ilana Ackerman, Rakesh Aggarwal, Stephanie Y Ahn, Mohammed K Ali, Mohammad A AlMazroa, Miriam Alvarado, H Ross Anderson, Laurie M Anderson, Kathryn G Andrews, Charles Atkinson, Larry M Baddour, Adil N Bahalim, Suzanne Barker-Collo, Lope H Barrero, David H Bartels, Maria-Gloria Basáñez, Amanda Baxter, Michelle L Bell, Emelia J Benjamin, Derrick Bennett, Eduardo Bernabé, Kavi Bhalla, Bishal Bhandari, Boris Bikbov, Aref Bin Abdulhak, Gretchen Birbeck, James A Black, Hannah Blencowe, Jed D Blore, Fiona Blyth, Ian Bolliger, Audrey Bonaventure, Soufiane Boufous, Rupert Bourne, Michel Boussinesq, Tasanee Braithwaite, Carol Brayne, Lisa Bridgett, Simon Brooker, Peter Brooks, Traolach S Brugha, Claire Bryan-Hancock, Chiara Bucello, Rachelle Buchbinder, Geoffrey Buckle, Christine M Budke, Michael Burch, Peter Burney, Roy Burstein, Bianca Calabria, Benjamin Campbell, Charles E Canter, Hélène Carabin, Jonathan Carapetis, Loreto Carmona, Claudia Cella, Fiona Charlson, Honglei Chen, Andrew Tai-Ann Cheng, David Chou, Sumeet S Chugh, Luc E Coffeng, Steven D Colan, Samantha Colquhoun, K Ellicott Colson, John Condon, Myles D Connor, Leslie T Cooper, Matthew Corriere, Monica Cortinovis, Karen Courville De Vaccaro, William Couser, Benjamin C Cowie, Michael H Criqui, Marita Cross, Kaustubh C Dabhadkar, Manu Dahiya, Nabila Dahodwala, James Damsere-Derry, Goodarz Danaei, Adrian Davis, Diego De Leo, Louisa Degenhardt, Robert Dellavalle, Allyne Delossantos, Julie Denenberg, Sarah Derrett, Don C Des Jarlais, Samath D Dharmaratne, Mukesh Dherani, Cesar Diaz-Torne, Helen Dolk, E Ray Dorsey, Tim Driscoll, Herbert Duber, Beth Ebel, Karen Edmond, Alexis Elbaz, Suad Eltahir Ali, Holly Erskine, Patricia J Erwin, Patricia Espindola, Stalin E Ewoigbokhan, Farshad Farzadfar, Valery Feigin, David T Felson, Alize Ferrari, Cleusa P Ferri, Eric M Fèvre, Mariel M Finucane, Seth Flaxman, Louise Flood, Kyle Foreman, Mohammad H Forouzanfar, Francis Gerry R Fowkes, Marlene Fransen, Michael K Freeman, Belinda J Gabbe, Sherine E Gabriel, Emmanuela Gakidou, Hammad A Ganatra, Bianca Garcia, Flavio Gaspari, Richard F Gillum, Gerhard Gmel, Diego Gonzalez-Medina, Richard Gosselin, Rebecca Grainger, Bridget Grant, Justina Groeger, Francis Guillemin, David Gunnell, Ramyani Gupta, Juanita Haagsma, Holly Hagan, Yara A Halasa, Wayne Hall, Diana Haring</div></div><div class="gs_scl"><div class="gsc_oci_field">Publication date</div><div class="gsc_oci_value">2012/12/15</div></div><div class="gs_scl"><div class="gsc_oci_field">Journal</div><div class="gsc_oci_value">The lancet</div></div><div class="gs_scl"><div class="gsc_oci_field">Volume</div><div class="gsc_oci_value">380</div></div><div class="gs_scl"><div class="gsc_oci_field">Issue</div><div class="gsc_oci_value">9859</div></div><div class="gs_scl"><div class="gsc_oci_field">Pages</div><div class="gsc_oci_value">2197-2223</div></div><div class="gs_scl"><div class="gsc_oci_field">Publisher</div><div class="gsc_oci_value">Elsevier</div></div><div class="gs_scl"><div class="gsc_oci_field">Description</div><div class="gsc_oci_value" id="gsc_oci_descr"><div class="gsh_small"><div class="gsh_h3 gsh_flh">Background</div><div class="gsh_csp">Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of ill-health. The 1990 Global Burden of Disease study proposed disability-adjusted life years (DALYs) to measure disease burden. No comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study. We aimed to calculate disease burden worldwide and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time.</div><div class="gsh_h3">Methods</div><div class="gsh_csp">We calculated DALYs as the sum of years of life lost (YLLs) and years lived with disability (YLDs). DALYs were calculated for 291 causes, 20 age groups, both sexes, and for 187 countries, and aggregated to regional and global estimates of disease burden for three points in time with …</div></div></div></div><div class="gs_scl"><div class="gsc_oci_field">Total citations</div><div class="gsc_oci_value"><div style="margin-bottom:1em"><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5">Cited by 11589</a></div><div id="gsc_oci_graph_wrapper"><div id="gsc_oci_graph" style="width:402px;"><div id="gsc_oci_graph_x"></div><div id="gsc_oci_graph_bars"><span class="gsc_oci_g_t" style="left:0px">2013</span><span class="gsc_oci_g_t" style="left:33px">2014</span><span class="gsc_oci_g_t" style="left:66px">2015</span><span class="gsc_oci_g_t" style="left:99px">2016</span><span class="gsc_oci_g_t" style="left:132px">2017</span><span class="gsc_oci_g_t" style="left:165px">2018</span><span class="gsc_oci_g_t" style="left:198px">2019</span><span class="gsc_oci_g_t" style="left:231px">2020</span><span class="gsc_oci_g_t" style="left:264px">2021</span><span class="gsc_oci_g_t" style="left:297px">2022</span><span class="gsc_oci_g_t" style="left:330px">2023</span><span class="gsc_oci_g_t" style="left:363px">2024</span><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2013&as_yhi=2013" class="gsc_oci_g_a" style="left:5px;height:19px;top:38px;z-index:12"><span class="gsc_oci_g_al">491</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2014&as_yhi=2014" class="gsc_oci_g_a" style="left:38px;height:43px;top:14px;z-index:11"><span class="gsc_oci_g_al">1094</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2015&as_yhi=2015" class="gsc_oci_g_a" style="left:71px;height:57px;top:0px;z-index:10"><span class="gsc_oci_g_al">1457</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2016&as_yhi=2016" class="gsc_oci_g_a" style="left:104px;height:53px;top:4px;z-index:9"><span class="gsc_oci_g_al">1356</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2017&as_yhi=2017" class="gsc_oci_g_a" style="left:137px;height:49px;top:8px;z-index:8"><span class="gsc_oci_g_al">1245</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2018&as_yhi=2018" class="gsc_oci_g_a" style="left:170px;height:44px;top:13px;z-index:7"><span class="gsc_oci_g_al">1127</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2019&as_yhi=2019" class="gsc_oci_g_a" style="left:203px;height:38px;top:19px;z-index:6"><span class="gsc_oci_g_al">978</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2020&as_yhi=2020" class="gsc_oci_g_a" style="left:236px;height:39px;top:18px;z-index:5"><span class="gsc_oci_g_al">985</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2021&as_yhi=2021" class="gsc_oci_g_a" style="left:269px;height:33px;top:24px;z-index:4"><span class="gsc_oci_g_al">838</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2022&as_yhi=2022" class="gsc_oci_g_a" style="left:302px;height:29px;top:28px;z-index:3"><span class="gsc_oci_g_al">732</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2023&as_yhi=2023" class="gsc_oci_g_a" style="left:335px;height:25px;top:32px;z-index:2"><span class="gsc_oci_g_al">628</span></a><a href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5&as_ylo=2024&as_yhi=2024" class="gsc_oci_g_a" style="left:368px;height:16px;top:41px;z-index:1"><span class="gsc_oci_g_al">406</span></a></div></div></div></div></div><div class="gs_scl"><div class="gsc_oci_field">Scholar articles</div><div class="gsc_oci_value"><div class="gsc_oci_merged_snippet"><div><a href="/scholar?oi=bibs&cluster=9833098564321204388&btnI=1&hl=en">Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010</a></div><div>CJL Murray, T Vos, R Lozano, M Naghavi, AD Flaxman… - The lancet, 2012</div><div><a class="gsc_oms_link" href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cites=9833098564321204388&as_sdt=5">Cited by 11589</a> <a class="gsc_oms_link" href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&q=related:pNjE1wsvdogJ:scholar.google.com/">Related articles</a> <a class="gsc_oms_link" href="https://scholar.google.co.in/scholar?oi=bibs&hl=en&cluster=9833098564321204388">All 87 versions</a> </div></div></div></div></div></div></div></div><div id="gs_ftr_sp" role="presentation"></div><div id="gs_ftr" class="gs_md_rmb" role="contentinfo"><div id="gs_ftr_rt"><a href="//www.google.co.in/intl/en/policies/privacy/">Privacy</a><a href="//www.google.co.in/intl/en/policies/terms/">Terms</a><a href="javascript:void(0)" ontouchstart="gs_evt_dsp(event)" role="button" aria-controls="gs_ftr_mnu" aria-haspopup="true" class="gs_press gs_md_tb">Help</a></div><div id="gs_ftr_mnu" class="gs_md_d gs_md_ds gs_ttzi gs_md_ulr" role="menu" tabindex="-1"><a role="menuitem" href="/intl/en/scholar/about.html" tabindex="-1" class="gs_md_li">About Scholar</a><a role="menuitem" href="//support.google.com/websearch?p=scholar_dsa&hl=en" tabindex="-1" class="gs_md_li">Search help</a></div></div></div></body></html>