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Search results for: bifunctional thrombolytic activity

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Count:</strong> 6249</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: bifunctional thrombolytic activity</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6249</span> A Promising Thrombolytic and Anticoagulant Serine Protease Purified from Lug Worms Inhabiting Tidal Flats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hye%20Jin%20Kim">Hye Jin Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hwa%20Sung%20Shin"> Hwa Sung Shin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ischemic stroke means the caused brain damage due to neurological defects, occurring occlusion of cerebral vascular resulting in thrombus or embolism. t-PA (tissue Plasminogen Activator) is the only thrombolytic agent passed the FDA (Food and Drug Administration). However, t-PA directly dissolves the thrombus (direct activity) through fibrinolysis, showing side effects such as re-occlusion. In this study, we evaluated the thrombolytic activities of the serine protease extracted from lugworms inhabiting tidal flats. The new serine protease identified as 38 kDa by SDS-PAGE was not toxic to brain endothelial cells line (hCMEC/D3). Also, the plasmin synthesis inhibition activity (indirect activity) of the new serine protease was confirmed through fibrin zymography assay and fibrin plate assay. It was higher than direct activity as compared to u-PA (urokinase Plasminogen Activator). The activities were found to be maintained at a wide range of temperature (4-70 ℃) and pH 7-10 compared to previous thrombolytic agents from the azocasein assay. In addition, the new serine protease has shown anticoagulant activity from fibrinogenolytic activity assay. In conclusion, the serine protease in lug worms inhabiting the tidal flats could be considered a promising thrombolytic candidate for the treatment of ischemic stroke. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alkaline%20serine%20protease" title="alkaline serine protease">alkaline serine protease</a>, <a href="https://publications.waset.org/abstracts/search?q=bifunctional%20thrombolytic%20activity" title=" bifunctional thrombolytic activity"> bifunctional thrombolytic activity</a>, <a href="https://publications.waset.org/abstracts/search?q=fibrinolytic%20activity" title=" fibrinolytic activity"> fibrinolytic activity</a>, <a href="https://publications.waset.org/abstracts/search?q=ischemic%20stroke" title=" ischemic stroke"> ischemic stroke</a>, <a href="https://publications.waset.org/abstracts/search?q=lug%20worms" title=" lug worms"> lug worms</a> </p> <a href="https://publications.waset.org/abstracts/75882/a-promising-thrombolytic-and-anticoagulant-serine-protease-purified-from-lug-worms-inhabiting-tidal-flats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/75882.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">328</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6248</span> Evaluation of Thrombolytic Activity of Zingiber cassumunar Roxb. and Thai Herbal Prasaplai Formula</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Warachate%20Khobjai">Warachate Khobjai</a>, <a href="https://publications.waset.org/abstracts/search?q=Suriyan%20Sukati"> Suriyan Sukati</a>, <a href="https://publications.waset.org/abstracts/search?q=Khemjira%20Jarmkom"> Khemjira Jarmkom</a>, <a href="https://publications.waset.org/abstracts/search?q=Pattaranut%20Eakwaropas"> Pattaranut Eakwaropas</a>, <a href="https://publications.waset.org/abstracts/search?q=Surachai%20Techaoei"> Surachai Techaoei</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The propose of this study was to investigate <em>in vitro</em> thrombolytic activity of <em>Zingiber cassumunar</em> Roxb. and Prasaplai, a Thai herbal formulation of <em>Z. cassumunar</em> Roxb. Herbs were extracted with boiling water and concentrated by lyophilization. To observe their thrombolytic potential, an <em>in vitro</em> clot lysis method was applied where streptokinase and sterile distilled water were used as positive and negative controls, respectively. Crude aqueous extracts from <em>Z. cassumunar</em> Roxb. and Prasaplai formula showed significant thrombolytic activity by clot lysis of 17.90% and 25.21%, respectively, compared to the negative control water (5.16%) while the standard streptokinase revealed 64.78% clot lysis. These findings suggest that <em>Z. cassumunar</em> Roxb. exhibits moderate thrombolytic activity and cloud play an important role in the thrombolytic properties of Prasaplai formula. However, further study should be done to observe <em>in vivo</em> clot dissolving potential and to isolate active component(s) of these extracts. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=thrombolytic%20activity" title="thrombolytic activity">thrombolytic activity</a>, <a href="https://publications.waset.org/abstracts/search?q=clot%20lysis" title=" clot lysis"> clot lysis</a>, <a href="https://publications.waset.org/abstracts/search?q=Zingiber%20cassumunar%20Roxb." title=" Zingiber cassumunar Roxb."> Zingiber cassumunar Roxb.</a>, <a href="https://publications.waset.org/abstracts/search?q=Prasaplai%20formula" title=" Prasaplai formula"> Prasaplai formula</a>, <a href="https://publications.waset.org/abstracts/search?q=aqueous%20extract" title=" aqueous extract"> aqueous extract</a> </p> <a href="https://publications.waset.org/abstracts/61567/evaluation-of-thrombolytic-activity-of-zingiber-cassumunar-roxb-and-thai-herbal-prasaplai-formula" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61567.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">338</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6247</span> Expression of Fused Plasmodium falciparum Orotate Phosphoribosyltransferase and Orotidine 5&#039;-Monophosphate Decarboxylase in Escherichia coli</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Waranya%20Imprasittichai">Waranya Imprasittichai</a>, <a href="https://publications.waset.org/abstracts/search?q=Patsarawadee%20Paojinda"> Patsarawadee Paojinda</a>, <a href="https://publications.waset.org/abstracts/search?q=Sudaratana%20R.%20Krungkrai"> Sudaratana R. Krungkrai</a>, <a href="https://publications.waset.org/abstracts/search?q=Nirianne%20Marie%20Q.%20Palacpac"> Nirianne Marie Q. Palacpac</a>, <a href="https://publications.waset.org/abstracts/search?q=Toshihiro%20Horii"> Toshihiro Horii</a>, <a href="https://publications.waset.org/abstracts/search?q=Jerapan%20Krungkrai"> Jerapan Krungkrai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Fusion of the last two enzymes in the pyrimidine biosynthetic pathway in the inversed order by having COOH-terminal orotate phosphoribosyltransferase (OPRT) and NH2-terminal orotidine 5'-monophosphate decarboxylase (OMPDC), as OMPDC-OPRT, are described in many organisms. In this study, we constructed gene fusions of Plasmodium falciparum OMPDC-OPRT (1,836 bp) in pTrcHisA vector and expressed as an 6xHis-tag bifunctional protein in three Escherichia coli strains (BL21, Rosetta, TOP10) at 18 °C, 25 °C and 37 °C. The recombinant bifunctional protein was partially purified by Ni-Nitrilotriacetic acid-affinity chromatography. Specific activities of OPRT and OMPDC domains in the bifunctional enzyme expressed in E. coli TOP10 cells were approximately 3-4-fold higher than those in BL21 cells. There were no enzymatic activities when the construct vector expressed in Rosetta cells. Maximal expression of the fused gene was observed at 18 °C and the bifunctional enzyme had specific activities of OPRT and OMPDC domains in a ratio of 1:2. These results provide greater yields and better catalytic activities of the bifunctional OMPDC-OPRT enzyme for further purification and kinetic study. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bifunctional%20enzyme" title="bifunctional enzyme">bifunctional enzyme</a>, <a href="https://publications.waset.org/abstracts/search?q=orotate%20phosphoribosyltransferase" title=" orotate phosphoribosyltransferase"> orotate phosphoribosyltransferase</a>, <a href="https://publications.waset.org/abstracts/search?q=orotidine%205%27-monophosphate%20decarboxylase" title=" orotidine 5&#039;-monophosphate decarboxylase"> orotidine 5&#039;-monophosphate decarboxylase</a>, <a href="https://publications.waset.org/abstracts/search?q=plasmodium%20falciparum" title=" plasmodium falciparum"> plasmodium falciparum</a> </p> <a href="https://publications.waset.org/abstracts/59256/expression-of-fused-plasmodium-falciparum-orotate-phosphoribosyltransferase-and-orotidine-5-monophosphate-decarboxylase-in-escherichia-coli" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59256.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">354</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6246</span> Bifunctional Activity and Stability of Fused Plasmodium falciparum Orotate Phosphoribosyltransferase and Orotidine 5′-Monophosphate Decarboxylase</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Patsarawadee%20Paojinda">Patsarawadee Paojinda</a>, <a href="https://publications.waset.org/abstracts/search?q=Waranya%20Imprasittichai"> Waranya Imprasittichai</a>, <a href="https://publications.waset.org/abstracts/search?q=Sudaratana%20R.%20Krungkrai"> Sudaratana R. Krungkrai</a>, <a href="https://publications.waset.org/abstracts/search?q=Nirianne%20Marie%20Q.%20Palacpac"> Nirianne Marie Q. Palacpac</a>, <a href="https://publications.waset.org/abstracts/search?q=Toshihiro%20Horii"> Toshihiro Horii</a>, <a href="https://publications.waset.org/abstracts/search?q=Jerapan%20Krungkrai"> Jerapan Krungkrai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Fusion of the last two enzymes in the pyrimidine biosynthetic pathway in the inversed order by having COOH-terminal orotate phosphoribosyltransferase (OPRT) and NH2-terminal orotidine 5'-monophosphate decarboxylase (OMPDC), as OMPDC-OPRT, are described in many organisms. Here, we produced gene fusions of Plasmodium falciparum OMPDC-OPRT and expressed the bifunctional protein in Escherichia coli. The enzyme was purified to homogeneity using affinity and anion-exchange chromatography, exhibited enzymatic activities and functioned as a dimer. The activities, although unstable, can be stabilized by its substrate and product during purification and long-term storage. Furthermore, the enzyme expressed a perfect catalytic efficiency (kcat/Km). The kcat was selectively enhanced up to 3 orders of magnitude, while the Km was not much affected and remained at low µM levels when compared to the monofunctional enzymes. The fusion of the two enzymes, creating a “super-enzyme” with perfect catalytic power and more flexibility, reflects cryptic relationship of enzymatic reactivaties and metabolic functions on molecular evolution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bifunctional%20enzyme" title="bifunctional enzyme">bifunctional enzyme</a>, <a href="https://publications.waset.org/abstracts/search?q=orotate%20phosphoribosyltransferase" title=" orotate phosphoribosyltransferase"> orotate phosphoribosyltransferase</a>, <a href="https://publications.waset.org/abstracts/search?q=orotidine%205%27-monophosphate%20decarboxylase" title=" orotidine 5&#039;-monophosphate decarboxylase"> orotidine 5&#039;-monophosphate decarboxylase</a>, <a href="https://publications.waset.org/abstracts/search?q=plasmodium%20falciparum" title=" plasmodium falciparum"> plasmodium falciparum</a> </p> <a href="https://publications.waset.org/abstracts/59255/bifunctional-activity-and-stability-of-fused-plasmodium-falciparum-orotate-phosphoribosyltransferase-and-orotidine-5-monophosphate-decarboxylase" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59255.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">285</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6245</span> Synthesis and Performance Study of Co3O4 as a Bi-Functional Next Generation Material</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shrikaant%20Kulkarni">Shrikaant Kulkarni</a>, <a href="https://publications.waset.org/abstracts/search?q=Akshata%20Naik%20Nimbalkar"> Akshata Naik Nimbalkar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this worki a method protocol has been developed for the synthesis of innovative Co3O4 material by using a method of chemical synthesis followed by calcination. The effect of calcination temperature on the morphology, structure and catalytic performance on material in question is investigated by using characterization tools like scanning electron microscopy (SEM), X-ray diffraction (XRD) spectroscopy and electrochemical techniques. The SEM images reveal that the morphology of the Co3O4 material undergoes a change from the rod to a beadlike shape on calcination at temperature of 700 °C. The XRD image shows that although the morphology of synthesized Co3O4 material exhibits a cubic phase but it differs in crystallinity depending upon morphology. Similarly spherical beadlike Co3O4 material has exhibited better activity than its rodlike counterpart which is reflected from electrochemical findings. Further, its performance in terms of bifunctional nature and hlods a lot much of promise as a excellent electrode material in the next generation batteries and fuel cells. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bifunctional" title="bifunctional">bifunctional</a>, <a href="https://publications.waset.org/abstracts/search?q=next%20generation%20material" title=" next generation material"> next generation material</a>, <a href="https://publications.waset.org/abstracts/search?q=Co3O4" title=" Co3O4"> Co3O4</a>, <a href="https://publications.waset.org/abstracts/search?q=XRD" title=" XRD"> XRD</a> </p> <a href="https://publications.waset.org/abstracts/16208/synthesis-and-performance-study-of-co3o4-as-a-bi-functional-next-generation-material" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16208.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">379</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6244</span> Influence of La on Increasing the ORR Activity of LaNi Supported with N and S Co-doped Carbon Black Electrocatalyst for Fuel Cells and Batteries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Kiani">Maryam Kiani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Non-precious electrocatalysts play a crucial role in the oxygen reduction reaction (ORR) for regenerative fuel cells and rechargeable metal-air batteries. To enhance ORR activity, La (a less active element) is added to modify the activity of Ni. This addition increases the surface contents of Ni2+, N, and S species in LaNi/N-S-C, while still maintaining a substantial specific surface area and hierarchical porosity. Therefore, the additional La is essential for the successful ORR process.In addition, the presence of extra La in the LaNi/N-S-C electrocatalyst enhances the efficiency of charge transfer and improves the surface acid-base characteristics, facilitating the adsorption of oxygen molecules during the ORR process. As a result, this superior and desirable electrocatalyst exhibits significantly enhanced ORR bifunctional activity. In fact, its ORR activity is comparable to that of the 20 wt% Pt/C. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fuel%20cells" title="fuel cells">fuel cells</a>, <a href="https://publications.waset.org/abstracts/search?q=batteries" title=" batteries"> batteries</a>, <a href="https://publications.waset.org/abstracts/search?q=dual-doped%20carbon%20black" title=" dual-doped carbon black"> dual-doped carbon black</a>, <a href="https://publications.waset.org/abstracts/search?q=ORR" title=" ORR"> ORR</a> </p> <a href="https://publications.waset.org/abstracts/172381/influence-of-la-on-increasing-the-orr-activity-of-lani-supported-with-n-and-s-co-doped-carbon-black-electrocatalyst-for-fuel-cells-and-batteries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172381.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">103</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6243</span> Mn3O4-NiFe Layered Double Hydroxides(LDH)/Carbon Composite Cathode for Rechargeable Zinc-Air Battery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20K.%20Nivedha">L. K. Nivedha</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Maruthapandian"> V. Maruthapandian</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Kothandaraman"> R. Kothandaraman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Rechargeable zinc-air batteries (ZAB) are gaining significant research attention owing to their high energy density and copious zinc resources worldwide. However, the unsolved obstacles such as dendrites, passivation, depth of discharge and the lack of an efficient cathode catalyst restrict their practical application1. By and large, non-noble transition metal-based catalysts are well-reputed materials for catalysing oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) with greater stability in alkaline medium2. Herein, we report the synthesis and application of Mn₃O4-NiFeLDH/Carbon composite as a cathode catalyst for rechargeable ZAB. The synergetic effects of the mixed transition metals (Mn/Ni/Fe) have aided in catalysing ORR and OER in alkaline electrolyte with a shallow potential gap of 0.7 V. The composite, by its distinctive physicochemical characteristics, shows an excellent OER activity with a current density of 1.5 mA cm⁻² at a potential of 1.6 V and a superior ORR activity with an onset potential of 0.8 V when compared with their counterparts. Nevertheless, the catalyst prefers a two-electron pathway for the electrochemical reduction of oxygen which results in a limiting current density of 2.5 mA cm⁻². The bifunctional activity of the Mn₃O₄-NiFeLDH/Carbon composite was utilized in developing rechargeable ZAB. The fully fabricated ZAB delivers an open circuit voltage of 1.4 V, a peak power density of 70 mW cm⁻², and a specific capacity of 800 mAh g⁻¹ at a current density of 20 mA cm⁻² with an average discharge voltage of 1 V and the cell is operable upto 50 mA cm-2. Rechargeable ZAB demonstrated over 110 h at 10 mA cm⁻². Further, the cause for the diminished charge-discharge performance experienced beyond the 100th cycle was investigated, and carbon corrosion was testified using Infrared spectroscopy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=rechargeable%20zinc-air%20battery" title="rechargeable zinc-air battery">rechargeable zinc-air battery</a>, <a href="https://publications.waset.org/abstracts/search?q=oxygen%20evolution%20reaction" title=" oxygen evolution reaction"> oxygen evolution reaction</a>, <a href="https://publications.waset.org/abstracts/search?q=bifunctional%20catalyst" title=" bifunctional catalyst"> bifunctional catalyst</a>, <a href="https://publications.waset.org/abstracts/search?q=alkaline%20medium" title=" alkaline medium"> alkaline medium</a> </p> <a href="https://publications.waset.org/abstracts/167265/mn3o4-nife-layered-double-hydroxidesldhcarbon-composite-cathode-for-rechargeable-zinc-air-battery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167265.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">80</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6242</span> The Study and the Use of the Bifunctional Catalyst Pt/Re for Obtaining High Octane Number of the Gasoline</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Menouar%20Hanafi">Menouar Hanafi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The original function of the process of platforming is to develop heavy naphtha (HSRN), coming from the atmospheric unit of distillation with a weak octane number (NO=44), to obtain a mixture of fuels â number octane raised by catalytically supporting specific groups of chemical reactions. The installation is divided into two sections: Section hydrobon. Section platforming. The rafinat coming from the bottom of column 12C2 to feed the section platforming, is divided into two parts whose flows are controlled and mixed with gas rich in hydrogen. Bottom of the column, we obtain stabilized reformat which is aspired by there pump to ensure the heating of the column whereas a part is sent towards storage after being cooled by the air cooler and the condenser. In catalytic catalyst of reforming, there is voluntarily associated a hydrogenating function-dehydrogenating, brought by platinum deposited, with an acid function brought by the alumina support (Al 2 0 3). The mechanism of action of this bifunctional catalyst depends on the severity of the operation, of the quality of the load and the type of catalyst. The catalyst used in the catalytic process of reforming is a very elaborate bifunctional catalyst whose performances are constantly improved thanks to the experimental research supported on an increasingly large comprehension of the phenomena. The American company Universel 0i1 petroleum (UOP) marketed several series of bimetallic catalysts such as R16, R20, R30, and R62 consisted Platinum/Rhenium on an acid support consisted the alumina added with a halogenous compound (chlorine). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=platforming" title="platforming">platforming</a>, <a href="https://publications.waset.org/abstracts/search?q=amelioration" title=" amelioration"> amelioration</a>, <a href="https://publications.waset.org/abstracts/search?q=octane%20number" title=" octane number"> octane number</a>, <a href="https://publications.waset.org/abstracts/search?q=catalyst" title=" catalyst"> catalyst</a> </p> <a href="https://publications.waset.org/abstracts/21579/the-study-and-the-use-of-the-bifunctional-catalyst-ptre-for-obtaining-high-octane-number-of-the-gasoline" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21579.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6241</span> Aspergillus micromycetes as Producers of Hemostatically Active Proteases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alexander%20A.%20Osmolovskiy">Alexander A. Osmolovskiy</a>, <a href="https://publications.waset.org/abstracts/search?q=Anastasia%20V.%20Orekhova"> Anastasia V. Orekhova</a>, <a href="https://publications.waset.org/abstracts/search?q=Daria%20M.%20Bednenko"> Daria M. Bednenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Yelyzaveta%20Boiko"> Yelyzaveta Boiko</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Micromycetes from Aspergillus genus can produce proteases capable of promoting proteolysis of hemostasis proteins or, along with hydrolytic activity, to show the ability to convert proenzymes of this system activating them into an active form. At the same time, practical medicine needs specific activators for quantitation of the level of some plasma enzymes, especially protein C and factor X, the lack of which leads to the development of thromboembolic diseases. Thus, some micromycetes of the genus Aspergillus were screened for the ability to synthesize extracellular proteases with promising activity for designing anti-thrombotic and diagnostic preparations. Such standard methods like salting out, electrophoresis, isoelectrofocusing were used for isolation, purification and study of physicochemical properties of proteases. Enzyme activity was measured spectrophotometrically fibrin as a substrate of the reaction and chromogenic peptide substrates of different proteases of the human hemostasis system. As a result of the screening, four active producers were selected: Aspergillus janus 301, A. flavus 1, A. terreus 2, and A. ochraceus L-1. The enzyme of A. janus 301 showed the greatest fibrinolytic activity (around 329.2 μmol Tyr/(ml × min)). The protease produced by A. terreus 2 had the highest plasmin-like activity (54.1 nmol pNA/(ml × min)), but fibrinolytic activity was lower than A. janus 301 demonstrated (25.2 μmol Tyr/(ml × min)). For extracellular protease of micromycete A. flavus a high plasmin-like activity was also shown (39.8 nmol pNA / (ml × min)). Moreover, according to our results proteases one of the fungi - A. terreus 2 were able to activate protein C of human plasma - the key factor of the human anticoagulant hemostasis system. This type of activity was 39.8 nmol pNA/(ml × min)). It was also shown that A. ochraceus L-1 could produce extracellular proteases with protein C and factor X activator activities (65.9 nmol pNA/(ml × min) and 34.6 nmol pNA/(ml × min) respectively). The maximum accumulation of the proteases falls on the 4th day of cultivation. Using isoelectrofocusing was demonstrated that the activation of both proenzymes might proceed via limited proteolysis induced by proteases of A. ochraceus L-1. The activatory activity of A. ochraceus L-1 proteases toward essential hemostatic proenzymes, protein C and X factor may be useful for practical needs. It is well known that similar enzymes, activators of protein C and X factor isolated from snake venom, South American copperhead Agkistrodon contortrix contortrix and Russell’s viper Daboia russelli russeli, respectively, are used for the in vitro diagnostics of the functional state of these proteins in blood plasma. Thus, the proteases of Aspergillus genus can be used as cheap components for enzyme thrombolytic preparations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti-trombotic%20drugs" title="anti-trombotic drugs">anti-trombotic drugs</a>, <a href="https://publications.waset.org/abstracts/search?q=fibrinolysis" title=" fibrinolysis"> fibrinolysis</a>, <a href="https://publications.waset.org/abstracts/search?q=diagnostics" title=" diagnostics"> diagnostics</a>, <a href="https://publications.waset.org/abstracts/search?q=proteases" title=" proteases"> proteases</a>, <a href="https://publications.waset.org/abstracts/search?q=micromycetes" title=" micromycetes "> micromycetes </a> </p> <a href="https://publications.waset.org/abstracts/118695/aspergillus-micromycetes-as-producers-of-hemostatically-active-proteases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118695.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">134</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6240</span> Impact of Zn/Cr Ratio on ZnCrOx-SAPO-34 Bifunctional Catalyst for Direct Conversion of Syngas to Light Olefins</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yuxuan%20Huang">Yuxuan Huang</a>, <a href="https://publications.waset.org/abstracts/search?q=Weixin%20Qian"> Weixin Qian</a>, <a href="https://publications.waset.org/abstracts/search?q=Hongfang%20Ma"> Hongfang Ma</a>, <a href="https://publications.waset.org/abstracts/search?q=Haitao%20Zhang"> Haitao Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Weiyong%20Ying"> Weiyong Ying</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Light olefins are important building blocks for chemical industry. Direct conversion of syngas to light olefins has been investigated for decades. Meanwhile, the limit for light olefins selectivity described by Anderson-Schulz-Flory (ASF) distribution model is still a great challenge to conventional Fischer-Tropsch synthesis. The emerging strategy called oxide-zeolite concept (OX-ZEO) is a promising way to get rid of this limit. ZnCrO<sub>x</sub> was prepared by co-precipitation method and (NH<sub>4</sub>)<sub>2</sub>CO<sub>3</sub> was used as precipitant. SAPO-34 was prepared by hydrothermal synthesis, and Tetraethylammonium hydroxide (TEAOH) was used as template, while silica sol, pseudo-boehmite, and phosphoric acid were Al, Si and P source, respectively. The bifunctional catalyst was prepared by mechanical mixing of ZnCrO<sub>x</sub> and SAPO-34. Catalytic reactions were carried out under H<sub>2</sub>/CO=2, 380 ℃, 1 MPa and 6000 mL&middot;g<sub>cat</sub><sup>-1</sup>&middot;h<sup>-1</sup> in a fixed-bed reactor with a quartz lining. Catalysts were characterized by XRD, N<sub>2</sub> adsorption-desorption, NH<sub>3</sub>-TPD, H<sub>2</sub>-TPR, and CO-TPD. The addition of Al as structure promoter enhances CO conversion and selectivity to light olefins. Zn/Cr ratio, which decides the active component content and chemisorption property of the catalyst, influences CO conversion and selectivity to light olefins at the same time. C<sub>2-4</sub><sup>=</sup> distribution of 86% among hydrocarbons at CO conversion of 14% was reached when Zn/Cr=1.5. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=light%20olefins" title="light olefins">light olefins</a>, <a href="https://publications.waset.org/abstracts/search?q=OX-ZEO" title=" OX-ZEO"> OX-ZEO</a>, <a href="https://publications.waset.org/abstracts/search?q=Syngas" title=" Syngas"> Syngas</a>, <a href="https://publications.waset.org/abstracts/search?q=ZnCrO%E2%82%93" title=" ZnCrOₓ"> ZnCrOₓ</a> </p> <a href="https://publications.waset.org/abstracts/93131/impact-of-zncr-ratio-on-zncrox-sapo-34-bifunctional-catalyst-for-direct-conversion-of-syngas-to-light-olefins" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93131.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6239</span> Microwave Heating and Catalytic Activity of Iron/Carbon Materials for H₂ Production from the Decomposition of Plastic Wastes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Peng%20Zhang">Peng Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Cai%20Liang"> Cai Liang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The non-biodegradable plastic wastes have posed severe environmental and ecological contaminations. Numerous technologies, such as pyrolysis, incineration, and landfilling, have already been employed for the treatment of plastic waste. Compared with conventional methods, microwave has displayed unique advantages in the rapid production of hydrogen from plastic wastes. Understanding the interaction between microwave radiation and materials would promote the optimization of several parameters for the microwave reaction system. In this work, various carbon materials have been investigated to reveal microwave heating performance and the ensuing catalytic activity. Results showed that the diversity in the heating characteristic was mainly due to the dielectric properties and the individual microstructures. Furthermore, the gaps and steps among the surface of carbon materials would lead to the distortion of the electromagnetic field, which correspondingly induced plasma discharging. The intensity and location of local plasma were also studied. For high-yield H₂ production, iron nanoparticles were selected as the active sites, and a series of iron/carbon bifunctional catalysts were synthesized. Apart from the high catalytic activity, the iron particles in nano-size close to the microwave skin depth would transfer microwave irradiation to the heat, intensifying the decomposition of plastics. Under microwave radiation, iron is supported on activated carbon material with 10wt.% loading exhibited the best catalytic activity for H₂ production. Specifically, the plastics were rapidly heated up and subsequently converted into H₂ with a hydrogen efficiency of 85%. This work demonstrated a deep understanding of microwave reaction systems and provided the optimization for plastic treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=plastic%20waste" title="plastic waste">plastic waste</a>, <a href="https://publications.waset.org/abstracts/search?q=recycling" title=" recycling"> recycling</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogen" title=" hydrogen"> hydrogen</a>, <a href="https://publications.waset.org/abstracts/search?q=microwave" title=" microwave"> microwave</a> </p> <a href="https://publications.waset.org/abstracts/167487/microwave-heating-and-catalytic-activity-of-ironcarbon-materials-for-h2-production-from-the-decomposition-of-plastic-wastes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167487.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">71</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6238</span> Preparation and Characterization of Modified ZnO Incorporated into Mesoporous MCM-22 Catalysts and Their Catalytic Performances of Crude Jatropha Oil to Biodiesel</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bashir%20Abubakar%20Abdulkadir">Bashir Abubakar Abdulkadir</a>, <a href="https://publications.waset.org/abstracts/search?q=Anita%20Ramli"> Anita Ramli</a>, <a href="https://publications.waset.org/abstracts/search?q=Lim%20Jun%20Wei"> Lim Jun Wei</a>, <a href="https://publications.waset.org/abstracts/search?q=Yoshimitsu%20Uemura"> Yoshimitsu Uemura</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the ZnO/MCM-22 catalyst with different ZnO loading were prepared using conventional wet impregnation process and the catalyst activity was tested for biodiesel production from Jatropha oil. The effects of reaction parameters with regards to catalyst activity were investigated. The synthesized catalysts samples were then characterized by X-ray diffraction (XRD) for crystal phase, Brunauer–Emmett–Teller (BET) for surface area, pore volume and pore size, Field Emission Scanning electron microscope attached to energy dispersive x-ray (FESEM/EDX) for morphology and elemental composition and TPD (NH3 and CO2) for basic and acidic properties of the catalyst. The XRD spectra couple with the EDX result shows the presence of ZnO in the catalyst confirming the positive intercalation of the metal oxide into the mesoporous MCM-22. The synthesized catalyst was confirmed to be mesoporous according to BET findings. Also, the catalysts can be considered as a bifunctional catalyst based on TPD outcomes. Transesterification results showed that the synthesized catalyst was highly efficient and effective to be used for biodiesel production from low grade oil such as Jatropha oil and other industrial application where the high fatty acid methyl ester (FAMEs) yield was achieved at moderate reaction conditions. It was also discovered that the catalyst can be used more than five (5) runs with little deactivation confirming the catalyst to be highly active and stable to the heat of reaction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MCM-22" title="MCM-22">MCM-22</a>, <a href="https://publications.waset.org/abstracts/search?q=synthesis" title=" synthesis"> synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=transesterification" title=" transesterification"> transesterification</a>, <a href="https://publications.waset.org/abstracts/search?q=ZnO" title=" ZnO"> ZnO</a> </p> <a href="https://publications.waset.org/abstracts/80401/preparation-and-characterization-of-modified-zno-incorporated-into-mesoporous-mcm-22-catalysts-and-their-catalytic-performances-of-crude-jatropha-oil-to-biodiesel" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80401.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">208</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6237</span> Antioxidant Activity of the Algerian Traditional Kefir Supernatant</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Amellal-Chibane">H. Amellal-Chibane</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Dehdouh"> N. Dehdouh</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Ait-Kaki"> S. Ait-Kaki</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20%20Halladj"> F. Halladj</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Kefir is fermented milk that is produced by adding Kefir grains, consisting of bacteria and yeasts, to milk. The aim of this study was to investigate the antioxidant activity of the kefir supernatant and the raw milk. The Antioxidant activity assays of kefir supernatant and raw milk were evaluated by assessing the DPPH radical-scavenging activity. Kefir supernatant demonstrated high antioxidant activity (87.75%) compared to the raw milk (70.59 %). These results suggest that the Algerian kefir has interesting antioxidant activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=kefir" title=" kefir"> kefir</a>, <a href="https://publications.waset.org/abstracts/search?q=kefir%20supernatant" title=" kefir supernatant"> kefir supernatant</a>, <a href="https://publications.waset.org/abstracts/search?q=raw%20milk" title=" raw milk "> raw milk </a> </p> <a href="https://publications.waset.org/abstracts/24330/antioxidant-activity-of-the-algerian-traditional-kefir-supernatant" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24330.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">506</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6236</span> Half Dose Tissue Plasminogen Activator for Intermediate-Risk Pulmonary Embolism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Macie%20Matta">Macie Matta</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Jabri"> Ahmad Jabri</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephanie%20Jackson"> Stephanie Jackson</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: In the absence of hypotension, pulmonary embolism (PE) causing right ventricular dysfunction or strain, whether confirmed by imaging or cardiac biomarkers, is deemed to be an intermediate-risk category. Urgent treatment of intermediate-risk PE can prevent progression to hemodynamic instability and death. Management options include thrombolysis, thrombectomy, or systemic anticoagulation. We aim to evaluate the short-term outcomes of a half-dose tissue plasminogen activator (tPA) for the management of intermediate-risk PE. Methods: We retrospectively identified adult patients diagnosed with intermediate-risk PE between the years 2000 and 2021. Demographic data, lab values, imaging, treatment choice, and outcomes were all obtained through chart review. Primary outcomes measured include major bleeding events and in-hospital mortality. Patients on standard systemic anticoagulation without receiving thrombolysis or thrombectomy served as controls. Patient data were analyzed using SAS®️ Software (version 9.4; Cary, NC) to compare individuals that received half-dose tPA with controls, and statistical significance was set at a p-value of 0.05. Results: We included 57 patients in our final analysis, with 19 receiving tPA. Patient characteristics and comorbidities were comparable between both groups. There was a significant difference between PE location, presence of acute deep vein thrombosis, and peak troponin level between both groups. The thrombolytic cohort was more likely to demonstrate a 60/60 sign and thrombus in transit finding on echocardiography than controls. The thrombolytic group was more likely to have major bleeding (17% vs 7.9%, p= 0.4) and in-hospital mortality (5.3% vs 0%, p=0.3); however, this was not statistically significant. Patients who received half-dose tPA had non-significantly higher rates of major bleeding and in-hospital mortality. Larger scale, randomized control trials are needed to establish the benefit and safety of thrombolytics in patients with intermediate-risk PE. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20embolism" title="pulmonary embolism">pulmonary embolism</a>, <a href="https://publications.waset.org/abstracts/search?q=half%20dose%20thrombolysis" title=" half dose thrombolysis"> half dose thrombolysis</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20plasminogen%20activator" title=" tissue plasminogen activator"> tissue plasminogen activator</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20biomarkers" title=" cardiac biomarkers"> cardiac biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=echocardiographic%20findings" title=" echocardiographic findings"> echocardiographic findings</a>, <a href="https://publications.waset.org/abstracts/search?q=major%20bleeding%20event" title=" major bleeding event"> major bleeding event</a> </p> <a href="https://publications.waset.org/abstracts/161710/half-dose-tissue-plasminogen-activator-for-intermediate-risk-pulmonary-embolism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161710.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6235</span> Synthesis and Characterization of Capric-Stearic Acid/ Graphene Oxide-TiO₂ Microcapsules for Solar Energy Storage and Photocatalytic Efficiency</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ghada%20Ben%20Hamad">Ghada Ben Hamad</a>, <a href="https://publications.waset.org/abstracts/search?q=Zohir%20Younsi"> Zohir Younsi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassane%20Naji"> Hassane Naji</a>, <a href="https://publications.waset.org/abstracts/search?q=Noureddine%20Lebaz"> Noureddine Lebaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Naoual%20Belouaggadia"> Naoual Belouaggadia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study deals with a bifunctional micro-encapsulated phase change (MCP) material, capric-stearic acid/graphene oxide-TiO2, which has been successfully developed by in situ hydrolysis and polycondensation of tetrabutyl titanate and modification of graphene oxide (GO) on the TiO2 doped shell. The use of graphene and doped TiO2 is a promising approach to provide photocatalytic activity under visible light and improve the microcapsules physicochemical properties. The morphology and chemical structure of the resulting microcapsule samples were determined by using Fourier transform infrared (FT-IR) spectroscopy, scanning electronic microscope (SEM), and X-ray diffractometer (XRD) methods. The ultraviolet, visible spectrophotometer (UV–vis), the differential scanning calorimeter (DSC) and the thermogravimetric analyzer (TGA) were used to investigate the absorption of visible and ultraviolet (UV), the thermal properties, and thermal stabilities of the microcapsules. Note that, the visible light photocatalytic activity was assessed for the toluene and benzene gaseous removal in a suitable test room. The microcapsules exhibit an interesting spherical morphology and an average diameter of 15 to 25 μm. The addition of graphene can enhance the rigidity of the shell and improve the microcapsules thermal reliability. At the same time, the thermal analysis tests showed that the synthesized microcapsules had a high solar thermal energy-storage and better thermal stability. In addition, the capric-stearic acid microcapsules exhibited high solar photocatalytic activity with respect to atmospheric pollutants under natural sunlight. The fatty acid samples obtained with the GO/TiO2 shell showed great potential for applications of solar energy storage, solar photocatalytic degradation of air pollutants and buildings energy conservation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=thermal%20energy%20storage" title="thermal energy storage">thermal energy storage</a>, <a href="https://publications.waset.org/abstracts/search?q=microencapsulation" title=" microencapsulation"> microencapsulation</a>, <a href="https://publications.waset.org/abstracts/search?q=titanium%20dioxide" title=" titanium dioxide"> titanium dioxide</a>, <a href="https://publications.waset.org/abstracts/search?q=photocatalysis" title=" photocatalysis"> photocatalysis</a>, <a href="https://publications.waset.org/abstracts/search?q=graphene%20oxide" title=" graphene oxide"> graphene oxide</a> </p> <a href="https://publications.waset.org/abstracts/103464/synthesis-and-characterization-of-capric-stearic-acid-graphene-oxide-tio2-microcapsules-for-solar-energy-storage-and-photocatalytic-efficiency" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/103464.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">131</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6234</span> Exploring the Bifunctional Organocatalysts for Asymmetric Synthesis of 3-Substituted-3-Aminooxindoles </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jasneet%20Kaur">Jasneet Kaur</a>, <a href="https://publications.waset.org/abstracts/search?q=Swapandeep%20Singh%20Chimni"> Swapandeep Singh Chimni</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The unfavorable use of metal-based catalysts that are often extortionate and toxic can be overcome by using small organic molecules known as organocatalysts. A variety of small organic molecules, including Brønsted/Lewis bases and acids, based on sulfonic acids, phosphoric acids, amines, phosphines or carbenes, Cinchona alkaloids, have been used as organocatalysts. One of the key reasons for using organocatalysis is their ability to be effectively removed from the final product in comparison to the metallic counterparts, which are exceedingly difficult to remove. The present investigation seeks to explore the catalytic nature of Cinchona alkaloids as an organocatalyst for enantioselective synthesis of 3-substituted-3-aminooxindole, which is known to exhibit a variety of biological activities and pharmacological activities. In this context, an organocatalytic asymmetric route for the synthesis of 3-aminooxindoles via reaction of isatin imine with α-acetoxy-β-ketoesters has been developed. The bifunctional Cinchona derived thiourea catalyzed the reaction of α-acetoxy-β-ketoesters derivatives with isatin imine to afford 3-substituted-aminooxindole derivatives in up to 93% yield, 95% enantiomeric excess and >20:1 diastereomeric ratio. The reaction was performed at room temperature for two hours using 10 mol% of catalyst, in the presence of 4Å molecular sieves in tetrahydrofuran as a solvent at ambient temperature. After the completion of the reaction, the pure product could be easily separated by using column chromatography using hexane and ethyl acetate as solvents. In conclusion, the catalytic potential of Cinchona derived chiral thiourea-tertiary amine catalyst was explored for an organocatalytic enantioselective Mannich reaction of β-ketoester derivatives with various isatin imine derivatives under mild conditions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=asymmetric%20synthesis" title="asymmetric synthesis">asymmetric synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=aminooxindoles" title=" aminooxindoles"> aminooxindoles</a>, <a href="https://publications.waset.org/abstracts/search?q=enantioselective" title=" enantioselective"> enantioselective</a>, <a href="https://publications.waset.org/abstracts/search?q=isatin%20imine" title=" isatin imine"> isatin imine</a> </p> <a href="https://publications.waset.org/abstracts/116751/exploring-the-bifunctional-organocatalysts-for-asymmetric-synthesis-of-3-substituted-3-aminooxindoles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/116751.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">114</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6233</span> Biological Activity of Essential Oils from Salvia nemorosa L.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdol-Hassan%20Doulah">Abdol-Hassan Doulah </a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, antimicrobial activity of essential oil and ethyl acetate and ether extracts of S. nemorosa were examined against some species of bacteria and fungi. The essential oil of the aerial part of S. nemorosa was examined by GC and GC-MS. In the essential oil of S. nemorosa 26 Compounds have been identified. 2-Nonanone (44.09 %), 2-Undecanone (33.79 %), E-Caryophyllene (3.74 %) and 2-Decanone (2.89 %) were the main components of the essential oil. The essential oil analysis showed greatest antimicrobial activity against Staphylococcus epidermidis (5.3 μg/ml) and S. cerevisiae (9.3 μg/ml). The ethyl acetate showed greatest antimicrobial activity against Bacillus subtilis (106.7 μg/ml), Candida albicans (5.3 μg/ml) and ether extract showed greatest antimicrobial activity against Klebseilla pneumoniae (10.7 μg/ml) and Saccharomyces cerevisiae (10.7 μg/ml). In conclusion, we suggest that the antimicrobial activity of S. nemorosa may be due to its content of germacrene and linalool. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title="antibacterial activity">antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=antifungal%20activity" title=" antifungal activity"> antifungal activity</a>, <a href="https://publications.waset.org/abstracts/search?q=Salvia%20nemorosa%20L." title=" Salvia nemorosa L."> Salvia nemorosa L.</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oils" title=" essential oils"> essential oils</a>, <a href="https://publications.waset.org/abstracts/search?q=biological%20activity" title=" biological activity"> biological activity</a> </p> <a href="https://publications.waset.org/abstracts/31804/biological-activity-of-essential-oils-from-salvia-nemorosa-l" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31804.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">493</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6232</span> Prevalence of Physical Activity Levels and Perceived Benefits of and Barriers to Physical Activity among Jordanian Patients with Coronary Heart Disease: A Cross-Sectional Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eman%20Ahmed%20Alsaleh">Eman Ahmed Alsaleh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Many studies published in other countries identified certain perceived benefits and barriers to physical activity among patients with coronary heart disease. Nevertheless, there is no data about the issue relating to Jordanian patients with coronary heart disease. Objective: This study aimed to describe the prevalence of level of physical activity, benefits of and barriers to physical activity as perceived by Jordanian patients with coronary heart disease, and the relationship between physical activity and perceived benefits of and barriers to physical activity. In addition, it focused on examining the influence of selected sociodemographic and health characteristics on physical activity and the perceived benefits of and barriers to physical activity. Methods: A cross-sectional design was performed on a sample of 400 patients with coronary heart disease. They were given a list of perceived benefits and barriers to physical activity and asked to what extent they disagreed or agreed with each. Results: Jordanian patients with coronary heart disease perceived various benefits and barriers to physical activity. Most of these benefits were physiologically related (average mean = 5.7, SD = .7). The most substantial barriers to physical activity as perceived by the patients were: feeling anxiety, not having enough time, lack of interest, bad weather, and feeling of being uncomfortable. Sociodemographic and health characteristics that significantly influenced perceived barriers to physical activity were age, gender, health perception, chest pain frequency, education, job, caring responsibilities, ability to travel alone, smoking, and previous and current physical activity behaviour. Conclusion: This research demonstrates that patients with coronary heart disease have perceived physiological benefits of physical activity, and they have perceived motivational, physical health, and environmental barriers to physical activity, which is significant in developing intervention strategies that aim to maximize patients' participation in physical activity and overcome barriers to physical activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=prevalence" title="prevalence">prevalence</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20heart%20disease" title=" coronary heart disease"> coronary heart disease</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20activity" title=" physical activity"> physical activity</a>, <a href="https://publications.waset.org/abstracts/search?q=perceived%20barriers" title=" perceived barriers"> perceived barriers</a> </p> <a href="https://publications.waset.org/abstracts/158570/prevalence-of-physical-activity-levels-and-perceived-benefits-of-and-barriers-to-physical-activity-among-jordanian-patients-with-coronary-heart-disease-a-cross-sectional-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158570.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">113</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6231</span> The Investigation of Correlation between Body Composition and Physical Activity in University Students</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ferruh%20Taspinar">Ferruh Taspinar</a>, <a href="https://publications.waset.org/abstracts/search?q=Gulce%20K.%20Seyyar"> Gulce K. Seyyar</a>, <a href="https://publications.waset.org/abstracts/search?q=Gamze%20Kurt"> Gamze Kurt</a>, <a href="https://publications.waset.org/abstracts/search?q=Eda%20O.%20Okur"> Eda O. Okur</a>, <a href="https://publications.waset.org/abstracts/search?q=Emrah%20Afsar"> Emrah Afsar</a>, <a href="https://publications.waset.org/abstracts/search?q=Ismail%20Saracoglu"> Ismail Saracoglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Betul%20Taspinar"> Betul Taspinar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Alterations of physical activity can effect body composition (especially body fat ratio); however body mass index may not sufficient to indicate these minimal differences. The aim of this study was to evaluate the relationship between body composition and physical activity in university students. In this study, 132 university students (mean age; 21.21±1.51) were included. Tanita BC-418 and International Physical Activity Questionnaire (IPAQ) were used to evaluate participants. The correlation between the parameters was analysed via Spearman correlation analysis. Significance level in statistical analyses was accepted is 0.05. The results showed that there was no correlation between body mass index and physical activity (p>0.05). There was a positive correlation between body muscle ratio and physical activity, whereas a negative correlation between body fat ratio and physical activity (p<0.05). This study showed that body fat and muscle ratio affects the level of physical activity in healthy university students. Therefore, we thought that physical activity might reduce effects of the diseases caused by disturbed body composition. Further studies are required to support this idea. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=body%20composition" title="body composition">body composition</a>, <a href="https://publications.waset.org/abstracts/search?q=body%20mass%20index" title=" body mass index"> body mass index</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20activity" title=" physical activity"> physical activity</a>, <a href="https://publications.waset.org/abstracts/search?q=university%20student" title=" university student"> university student</a> </p> <a href="https://publications.waset.org/abstracts/60659/the-investigation-of-correlation-between-body-composition-and-physical-activity-in-university-students" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60659.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">355</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6230</span> Chemical Composition and Antioxidant Activity of Methanolic Extract of Spilanthes acmella Murr.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Wanthani%20Paengsri">Wanthani Paengsri</a>, <a href="https://publications.waset.org/abstracts/search?q=Thanyarat%20Chuesaard"> Thanyarat Chuesaard</a>, <a href="https://publications.waset.org/abstracts/search?q=Napapha%20Promsawan"> Napapha Promsawan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Spilanthes acmella Murr. was extracted with methanol, yielding methanol crude extract 5.86 %w/w. This study aimed to examine the chemical composition and antioxidant activity of methanolic crude extract. The chemical composition of methanolic crude extract was analyzed by gas chromatography-mass spectrometry (GC-MS). The predominant components were found to be palmitic acid (40.08%), 2-hexadecanoyl glycerol (6.96%) and octadecanoic acid (4.06%). Antioxidant activity was determined using 2,2-diphenyl-1-picryl hydrazyl (DPPH) free radical, for evaluating free radicle scavenging activity. The methanolic extract at 150 µg/mL showed an antioxidant activity with high of radical scavenging activity (75.23%). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=GC-MS%20analysis" title=" GC-MS analysis"> GC-MS analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=Spilanthes" title=" Spilanthes"> Spilanthes</a>, <a href="https://publications.waset.org/abstracts/search?q=Phak-Kratt%20Hauwaen" title=" Phak-Kratt Hauwaen"> Phak-Kratt Hauwaen</a> </p> <a href="https://publications.waset.org/abstracts/80642/chemical-composition-and-antioxidant-activity-of-methanolic-extract-of-spilanthes-acmella-murr" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80642.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">531</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6229</span> Polyphenols Content and Antioxidant Activity of Extracts from Peganum harmala Seeds</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rachid%20Kacem">Rachid Kacem</a>, <a href="https://publications.waset.org/abstracts/search?q=Sara%20Talbi"> Sara Talbi</a>, <a href="https://publications.waset.org/abstracts/search?q=Yasmina%20Hemissi"> Yasmina Hemissi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sofia%20%20Bouguattoucha"> Sofia Bouguattoucha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the present work is the evaluation of the antioxidant activity of the Peganum harmala (P. harmala) seeds extracts. The antioxidant activity was evaluated by applying two methods, the method of ß-carotene bleaching and DPPH (2, 2-Diphenyl-1-Picryl-Hydrazyl). Using Folin-Ciocalteu assay, these results revealed that the concentration of polyphenols in EthOH E. (122.28 ± 2.24 µg GAE/mg extract) is the highest. The antiradical activity of the P. harmala seeds extracts on DPPH was found to be dose dependent with polyphenols concentration. The E. EthOH extract showed the highest antioxidant activity (IC = 252.10 ± 11.18 μg /ml). The test of β-carotene bleaching indicates that the E. EthOH of P. harmala showed the highest percentage of the antioxidant activity (49.88 %). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=Peganum%20harmala" title=" Peganum harmala"> Peganum harmala</a>, <a href="https://publications.waset.org/abstracts/search?q=polyphenols" title=" polyphenols"> polyphenols</a>, <a href="https://publications.waset.org/abstracts/search?q=flavonoids" title=" flavonoids "> flavonoids </a> </p> <a href="https://publications.waset.org/abstracts/32852/polyphenols-content-and-antioxidant-activity-of-extracts-from-peganum-harmala-seeds" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32852.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">506</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6228</span> Polyphenol and Antimicrobial Activity in Olive Oil from Algeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kamel%20Zemour">Kamel Zemour</a>, <a href="https://publications.waset.org/abstracts/search?q=Kada%20Mohamed%20Amine%20Chouhim"> Kada Mohamed Amine Chouhim</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Mairif"> Mohamed Mairif</a>, <a href="https://publications.waset.org/abstracts/search?q=Tadj%20Eddine%20Adda%20Ardjan"> Tadj Eddine Adda Ardjan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Many recent studies show the positive effect of phenolic compounds in olive oil on health. They are known for their biological properties, where they have shown potential activity as an antioxidant, anti-inflammatory, and antimicrobial agents. However, this characteristic is rarely studied in olive oil from different regions of Algeria. Different samples collected from the western region of Algeria were evaluated for their polyphenol content, antioxidant activity, and antimicrobial effect. The obtained results demonstrated that this oil is rich in polyphenols and revealed high antimicrobial activity against Staphylococcus aureus and Escherichia coli. Finally, this study has highlighted the nutritional and pharmaceutical importance of olive oil grown in Algeria. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=olive%20oil" title="olive oil">olive oil</a>, <a href="https://publications.waset.org/abstracts/search?q=polyphenols" title=" polyphenols"> polyphenols</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title=" antioxidant activity"> antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a> </p> <a href="https://publications.waset.org/abstracts/159649/polyphenol-and-antimicrobial-activity-in-olive-oil-from-algeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159649.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">152</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6227</span> The Effect of Solution pH of Chitosan on Antimicrobial Properties of Nylon 6,6 Fabrics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nil%C3%BCfer%20Y%C4%B1ld%C4%B1z%20Varan">Nilüfer Yıldız Varan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The antimicrobial activities of chitosan against various bacteria and fungi are well known, and the antimicrobial activity of chitosan depends on pH. This study investigates the antimicrobial activity at different pH levels. Nylon 6,6 fabrics were treated with different chitosan solutions. Additionally, samples were treated also in basic conditions to see the antimicrobial activities. AATCC Test Method 100 was followed to evaluate the antimicrobial activity using Staphylococcus aureus ATCC 6538 test inoculum. The pH of the chitosan solutions was controlled below 6.5 since chitosan shows its antimicrobial activity only in acidic conditions because of its poor solubility above 6.5. In basic conditions, the samples did not show any antimicrobial activity. It appears from SEM images that the bonded chitosan in the structures exists. In acidic media (ph < 6.5), all samples showed antimicrobial activity. No correlation was found between pH levels and antimicrobial activity in acidic media. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chitosan" title="chitosan">chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=nylon%206" title=" nylon 6"> nylon 6</a>, <a href="https://publications.waset.org/abstracts/search?q=6" title="6">6</a>, <a href="https://publications.waset.org/abstracts/search?q=crosslinking" title=" crosslinking"> crosslinking</a>, <a href="https://publications.waset.org/abstracts/search?q=pH%20stability" title=" pH stability"> pH stability</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial" title=" antimicrobial"> antimicrobial</a> </p> <a href="https://publications.waset.org/abstracts/74096/the-effect-of-solution-ph-of-chitosan-on-antimicrobial-properties-of-nylon-66-fabrics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74096.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">219</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6226</span> Immune Activity of Roman Hens as Influenced by the Feed Formulated with Germinated Paddy Rice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Wirot%20Likittrakulwong">Wirot Likittrakulwong</a>, <a href="https://publications.waset.org/abstracts/search?q=Pisit%20Poolprasert"> Pisit Poolprasert</a>, <a href="https://publications.waset.org/abstracts/search?q=Tossaporn%20Incharoen"> Tossaporn Incharoen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Germinated paddy rice (GPR) has the potential to be used as a feed ingredient. However, their properties have not been fully investigated. This paper examined the nutrient digestibility and the relationship to immune activity in Roman hens fed with GPR. It was found that true and apparent metabolizable energy (ME) values of GPR were 3.20 and 3.28 kcal/g air dry, respectively. GPR exhibited high content of phytonutrients, especially GABA. GPR showed similar protein profiles in comparison to non-germinated paddy rice. For immune activity, the feed with GPR enhanced the immune activity of Roman hens under high stocking density stress as evidenced by the activity of superoxide dismutase (SOD) and lysozyme activity. In this study, GPR is proved to be a good source of functional ingredient for chicken feed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=germinated%20paddy%20rice" title="germinated paddy rice">germinated paddy rice</a>, <a href="https://publications.waset.org/abstracts/search?q=nutrient%20digestibility" title=" nutrient digestibility"> nutrient digestibility</a>, <a href="https://publications.waset.org/abstracts/search?q=immune%20activity" title=" immune activity"> immune activity</a>, <a href="https://publications.waset.org/abstracts/search?q=functional%20property" title=" functional property"> functional property</a> </p> <a href="https://publications.waset.org/abstracts/110310/immune-activity-of-roman-hens-as-influenced-by-the-feed-formulated-with-germinated-paddy-rice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/110310.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6225</span> Activity Data Analysis for Status Classification Using Fitness Trackers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rock-Hyun%20Choi">Rock-Hyun Choi</a>, <a href="https://publications.waset.org/abstracts/search?q=Won-Seok%20Kang"> Won-Seok Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Chang-Sik%20Son"> Chang-Sik Son</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Physical activity is important for healthy living. Recently wearable devices which motivate physical activity are quickly developing, and become cheaper and more comfortable. In particular, fitness trackers provide a variety of information and need to provide well-analyzed, and user-friendly results. In this study, frequency analysis was performed to classify various data sets of Fitbit into simple activity status. The data from Fitbit cloud server consists of 263 subjects who were healthy factory and office workers in Korea from March 7th to April 30th, 2016. In the results, we found assumptions of activity state classification seem to be sufficient and reasonable. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=activity%20status" title="activity status">activity status</a>, <a href="https://publications.waset.org/abstracts/search?q=fitness%20tracker" title=" fitness tracker"> fitness tracker</a>, <a href="https://publications.waset.org/abstracts/search?q=heart%20rate" title=" heart rate"> heart rate</a>, <a href="https://publications.waset.org/abstracts/search?q=steps" title=" steps"> steps</a> </p> <a href="https://publications.waset.org/abstracts/83758/activity-data-analysis-for-status-classification-using-fitness-trackers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83758.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">384</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6224</span> Synthesis of [1-(Substituted-Sulfonyl)-Piperidin-4-yl]-(2,4-Difluoro-Phenyl)-Methanone Oximes and Their Biological Activity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20Mallesha">L. Mallesha</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20S.%20Karthik"> C. S. Karthik</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Mallu"> P. Mallu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A series of new [1-(substituted-benzoyl)-piperidin-4-yl]-(2,4-difluoro-phenyl)-methanone oxime derivatives, 3(a-f) were synthesized and characterized by different spectral studies. All compounds were evaluated for their in vitro antibacterial activity against bacterial strains. These compounds were screened for their antioxidant activity by DPPH• and Fe2+ chelating assay. Antiproliferative effects were evaluated using the MTT assay method against two human cancer cell lines and one astrocytoma brain tumor cell line. Compound 3b exhibited moderate antibacterial activity when compared with other compounds. All the compounds showed antioxidant activity, where compound 3f was the best radical scavenger and Fe2+ ion scavenger. Compounds, 3b, and 3d showed good activity on all cell lines, whereas the other compounds in the series exhibited moderate activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Piperidine" title="Piperidine">Piperidine</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial" title=" antibacterial"> antibacterial</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=antiproliferative" title=" antiproliferative"> antiproliferative</a> </p> <a href="https://publications.waset.org/abstracts/46525/synthesis-of-1-substituted-sulfonyl-piperidin-4-yl-24-difluoro-phenyl-methanone-oximes-and-their-biological-activity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46525.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">412</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6223</span> A New Phenolic Compound Isolated from Laurus nobilis from Lebanon and Comparison of Antioxidant Activity of Different Parts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Turk%20Ayman">Turk Ayman</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahn%20Jong%20Hoon"> Ahn Jong Hoon</a>, <a href="https://publications.waset.org/abstracts/search?q=Khalife%20K.%20Hala"> Khalife K. Hala</a>, <a href="https://publications.waset.org/abstracts/search?q=Gali-Muhtasib%20Hala"> Gali-Muhtasib Hala</a>, <a href="https://publications.waset.org/abstracts/search?q=Lee%20Mi%20Kyeong"> Lee Mi Kyeong </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Laurus nobilis is an aromatic plant widely distributed in the Mediterranean region. The leaves of this plant are frequently used as a spice and as a traditional medicine for several diseases. In our present study, the methanolic extract of L. nobilis leaves showed antioxidant activity. Chromatographic separations of the EtOAc fraction which had the highest antioxidant activity led to the isolation of 12 compounds. Among them, there was a new phenylpropanoid derivative, which was identified by 1D and 2D NMR experiments, as well as high resolution mass spectrometry. In addition, two major compounds, catechin and epicatechin, which showed strong antioxidant activity may be responsible for the antioxidant activity of L. nobilis leaves. Since different plant parts may contain different types of constituents which contribute to the biological activities, we investigated the antioxidant activity of different parts of L. nobilis such as leaves, stems and fruits. Stems of L. nobilis showed the most potent antioxidant activity, followed by leaves. Further quantitation of total phenol and flavonoids contents revealed a positive correlation between the content of these compounds and antioxidant activity. Taken together, phenolic compounds including flavonoids are responsible for antioxidant activity of L. nobilis. In addition, stem parts of L. nobilis are suggested as good sources for antioxidant activity. Conclusively, L. nobilis might be effective in several free radical mediated diseases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=different%20parts" title=" different parts"> different parts</a>, <a href="https://publications.waset.org/abstracts/search?q=Laurus%20nobilis" title=" Laurus nobilis"> Laurus nobilis</a>, <a href="https://publications.waset.org/abstracts/search?q=phenolic%20compound" title=" phenolic compound "> phenolic compound </a> </p> <a href="https://publications.waset.org/abstracts/56185/a-new-phenolic-compound-isolated-from-laurus-nobilis-from-lebanon-and-comparison-of-antioxidant-activity-of-different-parts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56185.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">307</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6222</span> Synthesis and Characterization of Some Mono Chloro-S-Triazine Vinyl Sulphone Reactive Dyes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nuradeen%20Abdullahi%20Nadabo">Nuradeen Abdullahi Nadabo</a>, <a href="https://publications.waset.org/abstracts/search?q=Kasali%20Adewale%20Bello"> Kasali Adewale Bello</a>, <a href="https://publications.waset.org/abstracts/search?q=Chindo%20Istifanus"> Chindo Istifanus</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A series of ten bi functional mono-chloro-s-triazine vinyl sulphone reactive dyes were synthesized based on H-acid with varied substituents coded as (BRD). These dyes were characterized by IR spectroscopy. The results revealed an incorporation of various substituents. The visible absorption spectra of these dyes were examined in various solvents and results shows positive and negative salvatochromism as the solvent polarity; changes, melting point, percentage yield and molar extinction co-efficient of these dyes were also evaluated and the results obtained are within a reasonable range acceptable for commercial dyeing. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bifunctional" title="bifunctional">bifunctional</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=reactive%20dyes" title=" reactive dyes"> reactive dyes</a>, <a href="https://publications.waset.org/abstracts/search?q=synthesis" title=" synthesis"> synthesis</a> </p> <a href="https://publications.waset.org/abstracts/18776/synthesis-and-characterization-of-some-mono-chloro-s-triazine-vinyl-sulphone-reactive-dyes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18776.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">435</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6221</span> Impacts and Implications: Exploring the Long-Term Health Benefits of Regular Physical Activity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Wahb">Muhammad Wahb</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Physical activity is increasingly recognized as a significant factor in maintaining optimal health and preventing chronic diseases. This research scrutinizes the long-term health benefits of sustained physical activity, employing a systematic review of epidemiological studies and randomized control trials conducted over the past decade. The study illuminates the protective effects of regular physical activity against cardiovascular disease, obesity, diabetes, and mental health disorders, with a special focus on the mechanisms involved. Furthermore, the paper provides insights into how public health initiatives can effectively promote physical activity among diverse populations, contributing to improved community health outcomes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=physical%20activity" title="physical activity">physical activity</a>, <a href="https://publications.waset.org/abstracts/search?q=long-term%20health%20benefits" title=" long-term health benefits"> long-term health benefits</a>, <a href="https://publications.waset.org/abstracts/search?q=chronic%20disease%20prevention" title=" chronic disease prevention"> chronic disease prevention</a>, <a href="https://publications.waset.org/abstracts/search?q=public%20health" title=" public health"> public health</a> </p> <a href="https://publications.waset.org/abstracts/170193/impacts-and-implications-exploring-the-long-term-health-benefits-of-regular-physical-activity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/170193.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">97</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6220</span> Level of Physical Activity and Physical Fitness, and Attitudes towards Physical Activity among Senior Medical Students of Sultan Qaboos University, Sultanate of Oman</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hajar%20Al%20Rajaibi">Hajar Al Rajaibi</a>, <a href="https://publications.waset.org/abstracts/search?q=Kawla%20Al%20Toubi"> Kawla Al Toubi</a>, <a href="https://publications.waset.org/abstracts/search?q=Saeed%20Al%20Jaadi"> Saeed Al Jaadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Deepali%20Jaju"> Deepali Jaju</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjay%20Jaju"> Sanjay Jaju</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The available evidence in Oman on lack of physical activity call for immediate intervention. Physical activity counseling by doctors to their patients is influenced by their attitudes and personal physical fitness. To our best knowledge, the physical activity status of Omani medical students has not been addressed before. These future doctors will have a critical role in improving physical activity in patients and thus their overall health. Objective: The aim of the study is to assess the physical activity level, physical fitness level, and attitudes towards physical activity among Sultan Qaboos University senior medical students. Methods: In this cross-sectional study (N=110; males 55), physical activity level was assessed using International Physical Activity Questionnaire (IPAQ ) short form and attitudes towards physical activity using a fifty-four-items Kenyon questionnaire. The physical fitness level was assessed by estimating maximal oxygen uptake (VO₂max) using Chester step test. Results: Female students reported more sitting time more than 7hr/day (85.5%) compared to male students (40%; p < 0.05). The IPAQ revealed moderate level of physical activity in 58% of students. Students showed a high positive attitude towards physical activity for health and fitness and low attitude for physical activity as tension and risk. Both female and male students had a similar level and attitude towards physical activity. Physical fitness level was excellent (VO₂max > 55ml O₂/kg/min) in 11% of students, good (VO₂max>44-54ml O₂/kg/min) in 49% and average to below-average in 40%. Objectively measured physical fitness level, subjectively reported physical activity level or attitudes towards physical activity were not correlated. Conclusion: Omani medical students have a positive attitude towards physical activity but moderate physical activity level. Longer sitting time in females need further evaluation. Efforts are required to understand reasons for present physical activity level and to promote good physical activity among medical students by creating more awareness and facilities. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chester%20step%20test" title="Chester step test">Chester step test</a>, <a href="https://publications.waset.org/abstracts/search?q=Kenyon%20scale" title=" Kenyon scale"> Kenyon scale</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20students" title=" medical students"> medical students</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20activity" title=" physical activity"> physical activity</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20fitness" title=" physical fitness"> physical fitness</a> </p> <a href="https://publications.waset.org/abstracts/110676/level-of-physical-activity-and-physical-fitness-and-attitudes-towards-physical-activity-among-senior-medical-students-of-sultan-qaboos-university-sultanate-of-oman" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/110676.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">153</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bifunctional%20thrombolytic%20activity&amp;page=2">2</a></li> <li class="page-item"><a class="page-link" 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