Early Clinical | Solutions

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height="136" alt="icon-and-you-mdd.jpg" loading="eager" title="icon-and-you-mdd.jpg" /> </div> </div> </div> <span class="h4">ICON and You</span> <p class="section-overview--desktop">Partners making a difference.</p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/therapeutics" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> Therapeutics <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><a href="/therapeutics" target="_self">Therapeutics</a></div> </div> <a class="dropdown-item" href="/therapeutics/cardiovascular">Cardiovascular</a> <a 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appropriate obesity-specific trial designs, long-term follow-up studies and diverse patient recruitment.</p> </a> </div> <div class="col-xl-3"> <a href="/insights/therapeutics" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/78559377-8cc3-4bc6-b6f2-cc20a04e1504/web/cells-menu-hero.jpg?crop=yes&w=260&h=136&itok=750H7OG2" width="260" height="136" alt="cells-menu-hero.jpg" loading="eager" title="cells-menu-hero.jpg" /> </div> </div> </div> <span class="h4">Therapeutics insights</span> <p class="section-overview--desktop">ICON's therapeutic experts contribute regularly to industry publications and the creation of thought leadership content. Read more. </p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/insights" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> Insights <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><a href="/insights" target="_self">Insights</a></div> </div> <a class="dropdown-item" href="/insights/digital-disruption">Digital Disruption</a> <a class="dropdown-item" href="/insights/patient-centricity">Patient Centricity</a> <a class="dropdown-item" href="/insights/regulatory-intelligence">Regulatory Intelligence</a> <a class="dropdown-item" 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efficient; the methods and technologies advancing Alzheimer’s and Parkinson’s R&D</span> <p class="section-overview--desktop">In this CNS whitepaper we examine how innovative methodologies and technologies are being implemented to improve the success rate of neurodegenerative clinical trials.</p> </a> </div> <div class="col-xl-3"> <a href="/sectors/biotech/early-phase-challenges-biotechs" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/fc13f816-bd06-455c-a1ae-4daf6cb35f40/web/Thumbnail_biotech_whitepaper.jpeg?crop=yes&w=260&h=136&itok=XglqHZSI" width="260" height="136" alt="Early phase challenges for biotechs_whitepaper" loading="eager" title="Early phase challenges for biotechs_whitepaper" /> </div> </div> </div> <span class="h4">Early phase challenges for biotechs</span> <p class="section-overview--desktop">Approaching early phase trials strategically and anticipating obstacles can be critical to the later success of a therapeutic</p> </a> </div> <div class="col-xl-3"> <a href="/insights/regulatory-intelligence/exploring-fda-guidance-modern-data-monitoring-committees" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/eaa349ef-9f6c-4c5c-b00f-e90cfc4bbedf/web/MDD_FDA_guidance_DMC.jpg?crop=yes&w=260&h=136&itok=KqupIbhv" width="260" height="136" alt="MDD_FDA_guidance_DMC.jpg" loading="eager" title="MDD_FDA_guidance_DMC.jpg" /> </div> </div> </div> <span class="h4">Exploring FDA guidance for modern Data Monitoring Committees</span> <p class="section-overview--desktop">What you need to know for compliant, efficient safety and efficacy monitoring</p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/news-events" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> News & Events <span></span> </a> <div 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src="https://icon.widen.net/content/eddc41a3-e26a-4b00-938f-7ba6fe776d32/web/Thumbnail_ACDs_webinar.jpg?crop=yes&w=260&h=136&itok=rTBCMcVB" width="260" height="136" alt="ACDs mollecule" loading="eager" title="ACDs mollecule" /> </div> </div> </div> <span class="h4">Strategies for ADC bioanalysis</span> <p class="section-overview--desktop">19 March 2025<br /> </p> </a> </div> <div class="col-xl-3"> <a href="/news-events/events/webinars/implementing-digital-health-technologies-patient-centred-trials" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/deed9bfc-d284-4b69-bb2b-0622ed48952a/web/DHT_wearable_Thumbnail_1110x678px.jpg?crop=yes&w=260&h=136&itok=4hwkD-Ew" width="260" height="136" alt="DHT_wearable" loading="eager" title="DHT_wearable" /> </div> </div> </div> <span class="h4">Implementing digital health technologies for patient-centred trials</span> <p class="section-overview--desktop">25 March 2025</p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/about" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> About ICON <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><a href="/about" target="_self">About ICON</a></div> </div> <a class="dropdown-item" href="/about/company-history">Company history</a> <a class="dropdown-item" href="/about/icon-glance">ICON at a glance</a> <a class="dropdown-item" href="/about/healthcare-intelligence">Healthcare Intelligence</a> <a class="dropdown-item" href="/about/icon-in-asia-pacific">ICON in 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Each clinic is supported by the expertise required to successfully deliver the most complex of healthy volunteer, patient, or hybrid first-in-human and proof-of-concept studies.</p></div> </div> </div> </div> </div> </a> </div> <div class="col-sm"> <a href="/solutions/early-clinical/expertise" class="block-link" target="_self"> <div class="container-full"> <div class="card card--title-description card--title-description-blue-light text-left"> <div class="card-body" data-mh="card-body"> <i class="icon-ui-arrow-right"></i> <h4 class="card-title">Clinical Pharmacology</h4> <div class="card-text small"> <div><p>Across all elements of your program from development plan to clinical study report, we apply integrated medical, scientific and operational excellence that’s dedicated to early phase development essential to reaching decision milestones on-time and with the highest quality insights.</p></div> </div> </div> </div> </div> </a> </div> <div class="col-sm"> <a href="/solutions/early-clinical/volunteer-recruitment" class="block-link" target="_self"> <div class="container-full"> <div class="card card--title-description card--title-description-purple text-left"> <div class="card-body" data-mh="card-body"> <i class="icon-ui-arrow-right"></i> <h4 class="card-title">Access to healthy volunteer and patient populations</h4> <div class="card-text small"> <div><p>Flexible volunteer recruitment solutions designed to serve the needs of your early phase clinical trial.</p></div> </div> </div> </div> </div> </a> </div> </div> </div> </div> </div> <div id="78085bbe-3125-4aa4-8ac6-cf5dcb082a27"> <div class="lead-text text-left bg-white"> <div class="container-fluid container-fluid--xl"> <h2> Innovative early clinical solutions that will advance your drug development strategy </h2> </div> </div> </div> <div id="8e255a5c-8ce6-4da2-8668-43a3828f18da" class="icon-group icon-group--horizontal"> <div class="container-fluid container-fluid--xl"> <ul class="icon-group__items icon-group__items__columns-3"> <li class="icon-group__item--green"> <div lang="en" class="icon-group__wrapper" > <i class="icon-sites"></i> <p class="mb-2 icons-large-text">6</p> <small>Clinical research units across Europe and the USA</small> </div> </li> <li class="icon-group__item--blue"> <div lang="en" class="icon-group__wrapper" > <i class="icon-research"></i> <p class="mb-2 icons-large-text">894</p> <small>Early phase clinical trials over the last 5 years</small> </div> </li> <li class="icon-group__item--purple"> <div lang="en" class="icon-group__wrapper" > <i class="icon-partnership-2"></i> <p class="mb-2 icons-large-text">32,600</p> <small>Healthy volunteers and patients targeted</small> </div> </li> </ul> </div> </div> <div id="73b5f495-fb6e-409d-9510-9cc657548f9c"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> </h3> <div><p>ICON is committed to the highest standards of excellence and scientific expertise in early clinical drug development.</p><p>We have extensive experience in the design, conduct, and interpretation of early phase first-in-human and proof of concept studies, providing the full suite of clinical pharmacology studies, all elements of a regulatory package programme, and translational early efficacy indication solutions in a range of study types including: </p><table style="width:100%;" border="0" cellpadding="1" cellspacing="1"><tbody><tr><td style="vertical-align:top;"><ul><li>Absorption, Metabolism, Excretion, (AME)</li><li>Bioavailability</li><li>Bioequivalence</li><li>Drug-drug interaction</li><li>Food Effect (FE)</li></ul></td><td style="vertical-align:top;"><ul><li>Hepatic Impairment</li><li>Human Abuse Liability</li><li>Microdose</li><li>Multiple Ascending Dose (MAD)</li><li>Phase 1 First in human</li></ul></td><td style="vertical-align:top;"><ul><li>Phase 1b/2a Proof of concept</li><li>Renal Impairment</li><li>Single Ascending Dose (SAD)</li><li>Thorough QT (TQT/) QTc</li></ul></td></tr></tbody></table></div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="d15e969a-fc3c-4480-ae9a-a92e4e291c28"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> </h3> <div><p>ICON’s early clinical services deliver full visibility and control to meet the requirements of increasingly complex clinical trial requirements. Our dedicated early phase specialists will engage with you to develop a trial that is best for your compound. Together we will build a tailored approach that leverages our <a href="https://www.iconplc.com/solutions/consulting">asset development consulting</a>, <a href="https://www.iconplc.com/solutions/early-clinical/expertise">clinical pharmacology expertise</a>, <a href="https://www.iconplc.com/solutions/early-clinical/clinical-research-units">extensive research facilities</a>, early phase operational experience, and <a href="https://www.iconplc.com/solutions/early-clinical/data-analysis">biometrics capabilities</a> to conduct your trial within both healthy volunteers and patient populations. </p></div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="5a5f840f-0fea-4dc1-8dd5-30416d685b5e"> <div class="group bg-transparent area-wrapper"> <div class="container-fluid container-fluid--xl"> <div class="area area--nav-left"> <ul class="area__nav area__nav--green"> <li> <a href="/solutions/consulting/asset-development" class="area__nav-item active has-link" target="_self" data-target="#area-item-0-140906-141246"> <span class="area__nav-title">Asset Development Consulting</span> <span class="area__nav-description">In-depth scientific expertise across disciplines.</span> </a> </li> <li> <a href="/solutions/early-phase/expertise" class="area__nav-item has-link" target="_self" data-target="#area-item-1-140906-130380"> <span class="area__nav-title">Clinical Pharmacology</span> <span class="area__nav-description">We help design a protocol that works harder and smarter for you.</span> </a> </li> <li> <a href="/solutions/early-phase/cmc" class="area__nav-item has-link" target="_self" data-target="#area-item-2-140906-130382"> <span class="area__nav-title">Accelerated Pharmaceutical Solutions</span> <span class="area__nav-description">A one stop drug development solution that is perfectly suited for early phase trials with shorter timelines. </span> </a> </li> <li> <a href="/solutions/early-phase/bioanalytical" class="area__nav-item has-link" target="_self" 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data-responsive-background-lg="https://icon.widen.net/content/8a79089f-a338-4233-a399-047a7a9bbcd2/web/control-tower-banner.png?crop=yes&w=1010&h=380&a=430,0&itok=1GA4l0h1" data-responsive-background-md="https://icon.widen.net/content/8a79089f-a338-4233-a399-047a7a9bbcd2/web/control-tower-banner.png?crop=yes&w=503&h=380&a=937,0&itok=T7eG2MDE" class="area__content-item has-link" id="area-item-7-140906-130387" href="/solutions/early-phase/pk-pd-data-analysis" target="_self"> <div class="area__content-item-overlay area__content-item-overlay--green-dark"></div> <h3 class="area__content-item-title">Quantitative Pharmacology and Pharmacometrics</h3> <p class="area__content-item-description">Expert clinical and nonclinical pharmacokinetic, pharmacodynamic, and exposure response data analysis services.</p> <div class="btn btn-outline-white">Explore</div> </a> <a data-responsive-backgrounds="true" data-responsive-background-lg="https://icon.widen.net/content/e51162b5-2dff-48b6-bfbf-0b52ec9b8164/web/healthy-volunteers.png?crop=yes&w=1010&h=380&a=430,0&itok=X3WOTLvb" data-responsive-background-md="https://icon.widen.net/content/e51162b5-2dff-48b6-bfbf-0b52ec9b8164/web/healthy-volunteers.png?crop=yes&w=503&h=380&a=937,0&itok=grEfIn20" class="area__content-item has-link" id="area-item-8-140906-141251" href="/solutions/early-clinical/volunteer-recruitment" target="_self"> <div class="area__content-item-overlay area__content-item-overlay--green-dark"></div> <h3 class="area__content-item-title">Healthy Volunteer Recruitment</h3> <p class="area__content-item-description">Flexible volunteer recruitment solutions designed to serve the needs of your early phase clinical trial.</p> <div class="btn btn-outline-white">Explore</div> </a> </div> </div> </div> </div> </div> <div id="c9a4a806-0077-4595-9497-eabecb6c9dbc"> <div class="bg-green-light group"> <div class="container-fluid container-fluid--xl"> <p class="group__text"> Our dedicated early clinical experts have the experience to address the most demanding early phase drug development challenges including: </p> <div class="row"> <div class="col-sm"> <div class="container-full"> <div class="key-message key-message--standard key-message--standard-blue"> <div class="key-message__body" data-mh="key-message"> <h4 class="key-message__title"> Increasing complexity of trials </h4> </div> <div class="key-message__image"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=5K3ehl6f 1x, https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=2CrZAXcF 2x" media="(min-width: 1400px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=f0fIVQHs 1x, https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=Y_IupWM0 2x" media="(min-width: 1200px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=clJTTqbd 1x, https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=8dOx_jrK 2x" media="(min-width: 992px) and (max-width: 1199px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=HxYonAVH 1x, https://icon.widen.net/content/knyzqe5x4z/web/homepage-complexity-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=Kq73UEQG 2x" media="(min-width: 768px) and (max-width: 991px)" width="270" height="270"/> <source 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</div> </div> </div> <div class="col-sm"> <div class="container-full"> <div class="key-message key-message--standard key-message--standard-blue"> <div class="key-message__body" data-mh="key-message"> <h4 class="key-message__title"> Delivery of reliable safety and efficacy data faster </h4> </div> <div class="key-message__image"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=x7GHpwVY 1x, https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=wfHKOjGt 2x" media="(min-width: 1400px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=dgHQJcAb 1x, https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=RiS8UIZK 2x" media="(min-width: 1200px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=naYOU2k0 1x, https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=w_1Xk9Mi 2x" media="(min-width: 992px) and (max-width: 1199px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=qLJiY2th 1x, https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=4ZD0zEcX 2x" media="(min-width: 768px) and (max-width: 991px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/mxtzwhdrra/web/reliable-data-and-efficacy-early-clinical-card.jpg?crop=yes&k=c&w=325&h=325&itok=ngS7cnUq 1x, 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key-message--standard key-message--standard-blue"> <div class="key-message__body" data-mh="key-message"> <h4 class="key-message__title"> Finding the right clinical settings to support complex assessment </h4> </div> <div class="key-message__image"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=A02YSETU 1x, https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=lQzZoPDU 2x" media="(min-width: 1400px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=s-aAPM-D 1x, https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=SPuxkV7x 2x" media="(min-width: 1200px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=S8bOEuYq 1x, https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=540&h=540&itok=GpxT_Y_3 2x" media="(min-width: 992px) and (max-width: 1199px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=WjrMyanT 1x, https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=270&h=270&itok=-lcMiqPM 2x" media="(min-width: 768px) and (max-width: 991px)" width="270" height="270"/> <source srcset="https://icon.widen.net/content/yu5rq6zqvl/web/finding-the-right-clinical-settings-early-clinical-card.jpg?crop=yes&k=c&w=325&h=325&itok=p9J2i5XM 1x, 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<div id="3233b904-7bc1-49f3-bfaa-9fdcda0975d2"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/jypi4jcfbg/web/Thumbnail_biotech_whitepaper.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=VWzgfKJF 1x, https://icon.widen.net/content/jypi4jcfbg/web/Thumbnail_biotech_whitepaper.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=VWzgfKJF 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/jypi4jcfbg/web/Thumbnail_biotech_whitepaper.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=VWzgfKJF 1x, 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</div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2>Early phase challenges for biotechs</h2> <h3></h3> <div><p dir="ltr">This whitepaper explores the growing challenges facing biotech during early phase drug development, and how these can be navigated to ensure the best possible outcomes.</p></div> <a class="btn btn-primary btn-md" href="/sectors/biotech/early-phase-challenges-biotechs" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="5a814930-ea7c-4083-9ab8-a36ed8bd5cad"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 1x, https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 1x, https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 1x, https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 1x, https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 1x, https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 1x, https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg?crop=yes&w=2048&h=1251&a=0,0&itok=gZUS8pnV 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/n2biidf8vx/web/Surveyreport_Thumbnail%20(landscape)_1.jpeg" width="3331" height="2035" alt="survey report" title="survey report" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2>ICON survey report: Early phase development - understanding key obstacles for biotechs in 2024</h2> <h3></h3> <div><p dir="ltr">ICON conducted a survey of 149 small and medium biotechs to understand the challenges they are currently experiencing in early phase drug development.</p></div> <a class="btn btn-primary btn-md" href="/sectors/biotech/early-phase-development-understanding-key-obstacles-biotechs-2024" target="_self" title="Read the survey report"> Read the survey report </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="bb76cb37-2093-4702-a688-5cf2b0d8f19f"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-4"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 1x, https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 1x, https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 1x, https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 1x, https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 1x, https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 1x, https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png?crop=yes&w=1110&h=678&a=0,0&itok=kGtetpDH 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/udq9mbr7rs/web/ISR%20logo%20landscape.png" width="1110" height="678" alt="ISR logo landscape" title="ISR logo landscape" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-8"> <div class="text-picture__text"> <h2></h2> <h3></h3> <div><p>In the latest<a href="https://research.isrreports.com/reportaction/2024-phase-i-cro-benchmarking/Marketing"> ISR Phase 1 CRO benchmarking survey</a> ICON outperforms other large CROs in 16 of the 17 operational metrics, with a significant lead differential in 11. We received our highest performance ratings on data quality, operational excellence, technology for real-time access to data, and patient/volunteer recruitment. Overall satisfaction with ICON for Phase 1 services has remained at last year’s all-time high and is amongst the very best of the large CROs. These results reflect our commitment to providing the very best early clinical drug development solutions.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div><div id="8abbb370-1dab-4cd9-b1ef-8b6f4d64263b"> <div class="group group--with-carousel bg-white content-visibility--auto contain-intrinsic-size--400 related-content-carousel"> <div class="container-fluid container-fluid--xl"> <h2 class="group__title"> Related Information </h2> <div class="carousel--standard carousel--standard-1-3-4"> <a class="carousel__item block-link" href="https://www2.iconplc.com/Fact_Sheet_Early_Phase_Development" target="_self"> <div class="card card--with-solid-bg 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