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J. Comput. Vis.</a> <a href="/?q=in%3A317597" title="Articles in this Issue">103, No. 1, 22-59 (2013)</a>. </div> <div class="abstract">Summary: This paper proposes an original approach for the statistical analysis of longitudinal shape data. The proposed method allows the characterization of typical growth patterns and subject-specific shape changes in repeated time-series observations of several subjects. This can be seen as the extension of usual longitudinal statistics of scalar measurements to high-dimensional shape or image data. The method is based on the estimation of continuous subject-specific growth trajectories and the comparison of such temporal shape changes across subjects. Differences between growth trajectories are decomposed into morphological deformations, which account for shape changes independent of the time, and time warps, which account for different rates of shape changes over time. Given a longitudinal shape data set, we estimate a mean growth scenario representative of the population, and the variations of this scenario both in terms of shape changes and in terms of change in growth speed. Then, intrinsic statistics are derived in the space of spatiotemporal deformations, which characterize the typical variations in shape and in growth speed within the studied population. They can be used to detect systematic developmental delays across subjects. In the context of neuroscience, we apply this method to analyze the differences in the growth of the hippocampus in children diagnosed with autism, developmental delays and in controls. Result suggest that group differences may be better characterized by a different speed of maturation rather than shape differences at a given age. In the context of anthropology, we assess the differences in the typical growth of the endocranium between chimpanzees and bonobos. We take advantage of this study to show the robustness of the method with respect to change of parameters and perturbation of the age estimates.</div> <div class="clear"></div> <br> <div class="citations"><div class="clear"><a href="/?q=rf%3A6199568">Cited in <strong>13</strong> Documents</a></div></div> <div class="classification"> <h3>MSC:</h3> <table><tr> <td> <a class="mono" href="/classification/?q=cc%3A68T45" title="MSC2020">68T45</a> </td> <td class="space"> Machine vision and scene understanding </td> </tr><tr> <td> <a class="mono" href="/classification/?q=cc%3A62P99" title="MSC2020">62P99</a> </td> <td class="space"> Applications of statistics </td> </tr><tr> <td> <a class="mono" href="/classification/?q=cc%3A62P10" title="MSC2020">62P10</a> </td> <td class="space"> Applications of statistics to biology and medical sciences; meta analysis </td> </tr></table> </div><div class="keywords"> <h3>Keywords:</h3><a href="/?q=ut%3Alongitudinal+data">longitudinal data</a>; <a href="/?q=ut%3Astatistics">statistics</a>; <a href="/?q=ut%3Agrowth">growth</a>; <a href="/?q=ut%3Ashape+regression">shape regression</a>; <a href="/?q=ut%3Aspatiotemporal+registration">spatiotemporal registration</a>; <a href="/?q=ut%3Atime+warp">time warp</a></div> <div class="software"> <h3>Software:</h3><a href="/software/6286">LDDMM</a></div> <!-- Modal used to show zbmath metadata in different output formats--> <div class="modal fade" id="metadataModal" tabindex="-1" role="dialog" aria-labelledby="myModalLabel"> <div class="modal-dialog" role="document"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> <h4 class="modal-title" id="myModalLabel">Cite</h4> </div> <div class="modal-body"> <div class="form-group"> <label for="select-output" class="control-label">Format</label> <select id="select-output" class="form-control" aria-label="Select Metadata format"></select> </div> <div class="form-group"> <label for="metadataText" class="control-label">Result</label> <textarea class="form-control" id="metadataText" rows="10" style="min-width: 100%;max-width: 100%"></textarea> </div> <div id="metadata-alert" class="alert alert-danger" role="alert" style="display: none;"> <!-- alert for connection errors etc --> </div> </div> <div class="modal-footer"> <button type="button" class="btn btn-primary" onclick="copyMetadata()">Copy to clipboard</button> <button type="button" class="btn btn-default" data-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="functions clearfix"> <div class="function"> <!-- Button trigger metadata modal --> <a type="button" class="btn btn-default btn-xs pdf" data-toggle="modal" data-target="#metadataModal" data-itemtype="Zbl" data-itemname="Zbl 1270.68345" data-ciurl="/ci/06199568" data-biburl="/bibtex/06199568.bib" data-amsurl="/amsrefs/06199568.bib" data-xmlurl="/xml/06199568.xml" > Cite </a> <a class="btn btn-default btn-xs pdf" data-container="body" type="button" href="/pdf/06199568.pdf" title="Zbl 1270.68345 as PDF">Review PDF</a> </div> <div class="fulltexts"> <span class="fulltext">Full Text:</span> <a class="btn btn-default btn-xs" type="button" href="https://doi.org/10.1007/s11263-012-0592-x" aria-label="DOI for “Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data”" title="10.1007/s11263-012-0592-x">DOI</a> </div> <div class="sfx" style="float: right;"> </div> </div> <div class="references"> <h3>References:</h3> <table><tr> <td>[1]</td> <td class="space">Aljabar, P., Bhatia, K., Murgasova, M., Hajnal, J., Boardman, J., Srinivasan, L., et al. 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