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class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown 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class="mw-page-title-main">Telmisartan</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 26 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-26" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">26 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AA%D9%84%D9%85%D9%8A%D8%B3%D8%A7%D8%B1%D8%AA%D8%A7%D9%86" title="تلميسارتان – Arabic" lang="ar" hreflang="ar" data-title="تلميسارتان" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%AA%D9%84%D9%85%DB%8C%D8%B2%D8%A7%D8%B1%D8%AA%D8%A7%D9%86" title="تلمیزارتان – South Azerbaijani" lang="azb" hreflang="azb" data-title="تلمیزارتان" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Welsh" lang="cy" hreflang="cy" data-title="Telmisartan" data-language-autonym="Cymraeg" data-language-local-name="Welsh" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Telmisartan" title="Telmisartan – German" lang="de" hreflang="de" data-title="Telmisartan" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A4%CE%B5%CE%BB%CE%BC%CE%B9%CF%83%CE%B1%CF%81%CF%84%CE%AC%CE%BD%CE%B7" title="Τελμισαρτάνη – Greek" lang="el" hreflang="el" data-title="Τελμισαρτάνη" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Telmisart%C3%A1n" title="Telmisartán – Spanish" lang="es" hreflang="es" data-title="Telmisartán" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AA%D9%84%D9%85%DB%8C%D8%B2%D8%A7%D8%B1%D8%AA%D8%A7%D9%86" title="تلمیزارتان – Persian" lang="fa" hreflang="fa" data-title="تلمیزارتان" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Telmisartan" title="Telmisartan – French" lang="fr" hreflang="fr" data-title="Telmisartan" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Indonesian" lang="id" hreflang="id" data-title="Telmisartan" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Italian" lang="it" hreflang="it" data-title="Telmisartan" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Telmizart%C3%A1n" title="Telmizartán – Hungarian" lang="hu" hreflang="hu" data-title="Telmizartán" data-language-autonym="Magyar" data-language-local-name="Hungarian" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Dutch" lang="nl" hreflang="nl" data-title="Telmisartan" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%86%E3%83%AB%E3%83%9F%E3%82%B5%E3%83%AB%E3%82%BF%E3%83%B3" title="テルミサルタン – Japanese" lang="ja" hreflang="ja" data-title="テルミサルタン" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%9F%E0%AD%87%E0%AC%B2%E0%AC%AE%E0%AC%BF%E0%AC%B8%E0%AC%BE%E0%AC%B0%E0%AD%8D%E0%AC%9F%E0%AC%BE%E0%AC%A8" title="ଟେଲମିସାର୍ଟାନ – Odia" lang="or" hreflang="or" data-title="ଟେଲମିସାର୍ଟାନ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Polish" lang="pl" hreflang="pl" data-title="Telmisartan" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Portuguese" lang="pt" hreflang="pt" data-title="Telmisartan" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Romanian" lang="ro" hreflang="ro" data-title="Telmisartan" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A2%D0%B5%D0%BB%D0%BC%D0%B8%D1%81%D0%B0%D1%80%D1%82%D0%B0%D0%BD" title="Телмисартан – Russian" lang="ru" hreflang="ru" data-title="Телмисартан" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Serbian" lang="sr" hreflang="sr" data-title="Telmisartan" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Telmisartan" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Telmisartaani" title="Telmisartaani – Finnish" lang="fi" hreflang="fi" data-title="Telmisartaani" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%9F%E0%AF%86%E0%AE%B2%E0%AF%8D%E0%AE%AE%E0%AE%BF%E0%AE%9A%E0%AE%BE%E0%AE%B0%E0%AF%8D%E0%AE%9F%E0%AE%A9%E0%AF%8D" title="டெல்மிசார்டன் – Tamil" lang="ta" hreflang="ta" data-title="டெல்மிசார்டன்" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Turkish" lang="tr" hreflang="tr" data-title="Telmisartan" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A2%D0%B5%D0%BB%D0%BC%D1%96%D1%81%D0%B0%D1%80%D1%82%D0%B0%D0%BD" title="Телмісартан – Ukrainian" lang="uk" hreflang="uk" data-title="Телмісартан" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Telmisartan" title="Telmisartan – Vietnamese" lang="vi" hreflang="vi" data-title="Telmisartan" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E6%9B%BF%E7%B1%B3%E6%B2%99%E5%9D%A6" title="替米沙坦 – Chinese" lang="zh" hreflang="zh" data-title="替米沙坦" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q733186#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> 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For other uses, see <a href="/wiki/Kinzhal_(disambiguation)" class="mw-redirect mw-disambig" title="Kinzhal (disambiguation)">Kinzhal</a>.</div> <p class="mw-empty-elt"> </p> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Pharmaceutical compound</div> <style data-mw-deduplicate="TemplateStyles:r1269284339">@media screen{html.skin-theme-clientpref-night .mw-parser-output .dark_mode_safe img{background-color:var(--background-color-inverted,#f8f9fa)}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .dark_mode_safe img{background-color:var(--background-color-inverted,#f8f9fa)}}</style> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Telmisartan">Telmisartan</span></caption><tbody><tr><td colspan="2" class="infobox-image"><span class="dark_mode_safe" typeof="mw:File"><a href="/wiki/File:Telmisartan.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/7/71/Telmisartan.svg/250px-Telmisartan.svg.png" decoding="async" width="220" height="218" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/71/Telmisartan.svg/330px-Telmisartan.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/71/Telmisartan.svg/500px-Telmisartan.svg.png 2x" data-file-width="512" data-file-height="507" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">Pronunciation</th><td class="infobox-data"><span class="rt-commentedText nowrap"><span class="IPA nopopups noexcerpt" lang="en-fonipa"><a href="/wiki/Help:IPA/English" title="Help:IPA/English">/<span style="border-bottom:1px dotted"><span title="'t' in 'tie'">t</span><span title="/ɛ/: 'e' in 'dress'">ɛ</span><span title="'l' in 'lie'">l</span><span title="'m' in 'my'">m</span><span title="/ɪ/: 'i' in 'kit'">ɪ</span><span title="/ˈ/: primary stress follows">ˈ</span><span title="'s' in 'sigh'">s</span><span title="/ɑːr/: 'ar' in 'far'">ɑːr</span><span title="'t' in 'tie'">t</span><span title="/ən/: 'on' in 'button'">ən</span></span>/</a></span></span> </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_nomenclature#Trade_names" title="Drug nomenclature">Trade names</a></th><td class="infobox-data">Micardis, others</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/American_Society_of_Health-System_Pharmacists" title="American Society of Health-System Pharmacists">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data"><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/monograph/telmisartan.html">Monograph</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th><td class="infobox-data"><span title="medlineplus.gov"><a rel="nofollow" class="external text" href="https://medlineplus.gov/druginfo/meds/a601249.html">a601249</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">License data</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"> <ul><li><small><abbr class="country-name" title="United States">US</abbr></small> <a href="/wiki/DailyMed" title="DailyMed">DailyMed</a>: <span title="dailymed.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Telmisartan">Telmisartan</a></span></li></ul></div> </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Pregnancy_category" title="Pregnancy category">Pregnancy<br />category</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> D<sup id="cite_ref-Preg2019_1-0" class="reference"><a href="#cite_note-Preg2019-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></li> <li>Not recommended<sup id="cite_ref-Preg2019_1-1" class="reference"><a href="#cite_note-Preg2019-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Route_of_administration" title="Route of administration">Routes of<br />administration</a></th><td class="infobox-data"><a href="/wiki/Oral_administration" title="Oral administration">By mouth</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_class" title="Drug class">Drug class</a></th><td class="infobox-data"><a href="/wiki/Angiotensin_II_receptor_antagonist" class="mw-redirect" title="Angiotensin II receptor antagonist">Angiotensin II receptor antagonist</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><a href="/wiki/ATC_code_C09" title="ATC code C09">C09CA07</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=C09CA07">WHO</a></span>) </li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Legal status</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> <a href="/wiki/Standard_for_the_Uniform_Scheduling_of_Medicines_and_Poisons#Schedule_4" title="Standard for the Uniform Scheduling of Medicines and Poisons">S4</a> (Prescription only)</li> <li><small><abbr class="country-name" title="Canada">CA</abbr></small>: <a href="/wiki/Prescription_drug" title="Prescription drug"> ℞-only</a></li> <li><small><abbr class="country-name" title="United Kingdom">UK</abbr>:</small> <a href="/wiki/Prescription_drug" title="Prescription drug">POM</a> (Prescription only)</li> <li><small><abbr class="country-name" title="United States">US</abbr>:</small> <a href="/wiki/Boxed_warning" title="Boxed warning"><span style="border:thin solid black;">WARNING</span></a><sup id="cite_ref-FDA-AllBoxedWarnings_2-0" class="reference"><a href="#cite_note-FDA-AllBoxedWarnings-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>Rx-only<sup id="cite_ref-Micardis_FDA_label_3-0" class="reference"><a href="#cite_note-Micardis_FDA_label-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="European Union">EU</abbr>:</small> Rx-only<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;"><a href="/wiki/Pharmacokinetics" title="Pharmacokinetics">Pharmacokinetic</a> data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Bioavailability" title="Bioavailability">Bioavailability</a></th><td class="infobox-data">42–100%</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Plasma_protein_binding" title="Plasma protein binding">Protein binding</a></th><td class="infobox-data">>99.5%</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_metabolism" title="Drug metabolism">Metabolism</a></th><td class="infobox-data">Minimal liver (<a href="/wiki/Glucuronidation" title="Glucuronidation">glucuronidation</a>)</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Biological_half-life" title="Biological half-life">Elimination <span class="nowrap">half-life</span></a></th><td class="infobox-data">24 hours</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Excretion" title="Excretion">Excretion</a></th><td class="infobox-data">Feces 97%</td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Identifiers</th></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC_nomenclature_of_chemistry" title="IUPAC nomenclature of chemistry">IUPAC name</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">2-(4-{[4-Methyl-6-(1-methyl-1<i>H</i>-1,3-benzodiazol-2-yl)-2-propyl-1<i>H</i>-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid</div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=144701-48-4">144701-48-4</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/PubChem#CID" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/65999">65999</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Guide_to_Pharmacology" title="Guide to Pharmacology">IUPHAR/BPS</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.guidetopharmacology.org"><a rel="nofollow" class="external text" href="https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=592">592</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB00966">DB00966</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.59391.html">59391</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/U5SYW473RQ">U5SYW473RQ</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D00627">D00627</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:9434">CHEBI:9434</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/explore/compound/ChEMBL1017">ChEMBL1017</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID8023636">DTXSID8023636</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q733186#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.149.347">100.149.347</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q733186#P2566" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Carbon">C</span><sub>33</sub><span title="Hydrogen">H</span><sub>30</sub><span title="Nitrogen">N</span><sub>4</sub><span title="Oxygen">O</span><sub>2</sub></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7002514629000000000♠"></span>514.629</span> g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=O%3DC%28O%29c1ccccc1c2ccc%28cc2%29Cn3c4cc%28cc%28c4nc3CCC%29C%29c5nc6ccccc6n5C">Interactive image</a></span></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">O=C(O)c1ccccc1c2ccc(cc2)Cn3c4cc(cc(c4nc3CCC)C)c5nc6ccccc6n5C</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:RMMXLENWKUUMAY-UHFFFAOYSA-N<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-below"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold">  <span class="reflink plainlinks nourlexpansion"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special:ComparePages&rev1=477861448&page2=Telmisartan">(verify)</a></span></span></td></tr></tbody></table> <p><b>Telmisartan</b>, sold under the brand name <b>Micardis</b> among others, is a <a href="/wiki/Medication" title="Medication">medication</a> used to treat <a href="/wiki/Hypertension" title="Hypertension">high blood pressure</a> and <a href="/wiki/Heart_failure" title="Heart failure">heart failure</a>.<sup id="cite_ref-Micardis_FDA_label_3-1" class="reference"><a href="#cite_note-Micardis_FDA_label-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-AHFS2019_6-0" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> It is a reasonable initial treatment for high blood pressure.<sup id="cite_ref-AHFS2019_6-1" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> It is taken <a href="/wiki/By_mouth" class="mw-redirect" title="By mouth">by mouth</a>.<sup id="cite_ref-AHFS2019_6-2" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Common side effects include <a href="/wiki/Upper_respiratory_tract_infections" class="mw-redirect" title="Upper respiratory tract infections">upper respiratory tract infections</a>, diarrhea, and back pain.<sup id="cite_ref-AHFS2019_6-3" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> Serious side effects may include <a href="/wiki/Kidney_problems" class="mw-redirect" title="Kidney problems">kidney problems</a>, <a href="/wiki/Low_blood_pressure" class="mw-redirect" title="Low blood pressure">low blood pressure</a>, and <a href="/wiki/Angioedema" title="Angioedema">angioedema</a>.<sup id="cite_ref-AHFS2019_6-4" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> Use in <a href="/wiki/Pregnancy" title="Pregnancy">pregnancy</a> may harm the baby and use when <a href="/wiki/Breastfeeding" title="Breastfeeding">breastfeeding</a> is not recommended.<sup id="cite_ref-Preg2019_1-2" class="reference"><a href="#cite_note-Preg2019-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> It is an <a href="/wiki/Angiotensin_II_receptor_blocker" title="Angiotensin II receptor blocker">angiotensin II receptor blocker</a> and works by blocking the effects of <a href="/wiki/Angiotensin_II" class="mw-redirect" title="Angiotensin II">angiotensin II</a>.<sup id="cite_ref-AHFS2019_6-5" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Telmisartan was patented in 1991 and came into medical use in 1999.<sup id="cite_ref-Fis2006_7-0" class="reference"><a href="#cite_note-Fis2006-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> It is available as a <a href="/wiki/Generic_medication" class="mw-redirect" title="Generic medication">generic medication</a>.<sup id="cite_ref-BNF76_8-0" class="reference"><a href="#cite_note-BNF76-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> In 2022, it was the 228th most commonly prescribed medication in the United States, with more than 1<span class="nowrap"> </span>million prescriptions.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> It is available in combination with hydrochlorothiazide as <a href="/wiki/Telmisartan/hydrochlorothiazide" title="Telmisartan/hydrochlorothiazide">telmisartan/hydrochlorothiazide</a>;<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> with cilnidipine as telmisartan/cilnidipine;<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> and with amlodipine as <a href="/wiki/Telmisartan/amlodipine" title="Telmisartan/amlodipine">telmisartan/amlodipine</a>.<sup id="cite_ref-AHFS2019_6-6" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Medical_uses">Medical uses</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=1" title="Edit section: Medical uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Telmisartan is used to treat <a href="/wiki/Hypertension" title="Hypertension">high blood pressure</a>, <a href="/wiki/Heart_failure" title="Heart failure">heart failure</a>, and <a href="/wiki/Diabetic_kidney_disease" class="mw-redirect" title="Diabetic kidney disease">diabetic kidney disease</a>.<sup id="cite_ref-AHFS2019_6-7" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> It is a reasonable initial treatment for high blood pressure.<sup id="cite_ref-AHFS2019_6-8" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Opie_2009_14-0" class="reference"><a href="#cite_note-Opie_2009-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup class="reference nowrap"><span title="Page / location: 146">: 146 </span></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Contraindications">Contraindications</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=2" title="Edit section: Contraindications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Telmisartan is contraindicated during <a href="/wiki/Pregnancy" title="Pregnancy">pregnancy</a>.<sup id="cite_ref-Micardis_FDA_label_3-2" class="reference"><a href="#cite_note-Micardis_FDA_label-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-AHFS2019_6-9" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Preg2019_1-3" class="reference"><a href="#cite_note-Preg2019-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Telmisartan affects the <a href="/wiki/Renin%E2%80%93angiotensin_system" title="Renin–angiotensin system">renin–angiotensin system</a> and can cause <a href="/wiki/Birth_defect" title="Birth defect">birth defects</a>, <a href="/wiki/Stillbirth" title="Stillbirth">stillbirths</a>, and <a href="/wiki/Neonatal_death" class="mw-redirect" title="Neonatal death">neonatal deaths</a>.<sup id="cite_ref-Micardis_FDA_label_3-3" class="reference"><a href="#cite_note-Micardis_FDA_label-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-AHFS2019_6-10" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> It is not known whether the medication passes into breast milk.<sup id="cite_ref-AHFS2019_6-11" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Side_effects">Side effects</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=3" title="Edit section: Side effects"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Side effects include <a href="/wiki/Tachycardia" title="Tachycardia">tachycardia</a> and <a href="/wiki/Bradycardia" title="Bradycardia">bradycardia</a> (fast or slow heartbeat), <a href="/wiki/Hypotension" title="Hypotension">hypotension</a> (low blood pressure) and <a href="/wiki/Edema" title="Edema">edema</a> (swelling of arms, legs, lips, tongue, or throat, the latter leading to breathing problems). <a href="/wiki/Allergic_reaction" class="mw-redirect" title="Allergic reaction">Allergic reactions</a> may also occur.<sup id="cite_ref-AHFS2019_6-12" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Interactions">Interactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=4" title="Edit section: Interactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Due to its mechanism of action, telmisartan increases blood <a href="/wiki/Potassium" title="Potassium">potassium</a> levels. Combination with potassium preparations or <a href="/wiki/Potassium-sparing_diuretic" title="Potassium-sparing diuretic">potassium-sparing diuretics</a> could cause <a href="/wiki/Hyperkalaemia" class="mw-redirect" title="Hyperkalaemia">hyperkalaemia</a> (excessive potassium levels). Combination with <a href="/wiki/NSAIDs" class="mw-redirect" title="NSAIDs">NSAIDs</a>, especially in patients with impaired kidney function, has a risk of causing (usually reversible) <a href="/wiki/Kidney_failure" title="Kidney failure">kidney failure</a>.<sup id="cite_ref-AC_15-0" class="reference"><a href="#cite_note-AC-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Pharmacology">Pharmacology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=5" title="Edit section: Pharmacology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Mechanism_of_action">Mechanism of action</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=6" title="Edit section: Mechanism of action"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Telmisartan is an angiotensin II receptor blocker that shows high affinity for the <a href="/wiki/Angiotensin_II_receptor_type_1" title="Angiotensin II receptor type 1">angiotensin II receptor type 1</a> (AT<sub>1</sub>), with a binding affinity 3000 times greater for AT<sub>1</sub> than <a href="/wiki/Angiotensin_II_receptor_type_2" title="Angiotensin II receptor type 2">AT<sub>2</sub></a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (February 2025)">citation needed</span></a></i>]</sup> </p> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/PPAR_agonist" title="PPAR agonist">PPAR agonist</a></div> <p>In addition to blocking the <a href="/wiki/Renin%E2%80%93angiotensin_system" title="Renin–angiotensin system">renin–angiotensin system</a>, telmisartan acts as a partial agonist of <a href="/wiki/Peroxisome_proliferator-activated_receptor_gamma" title="Peroxisome proliferator-activated receptor gamma">peroxisome proliferator-activated receptor gamma</a> (PPAR-γ), a central regulator of <a href="/wiki/Insulin" title="Insulin">insulin</a> and <a href="/wiki/Glucose" title="Glucose">glucose</a> metabolism. It is believed that telmisartan's dual mode of action may provide protective benefits against the vascular and renal damage caused by <a href="/wiki/Diabetes" title="Diabetes">diabetes</a> and <a href="/wiki/Cardiovascular_disease" title="Cardiovascular disease">cardiovascular disease</a> (CVD).<sup id="cite_ref-Benson_SC_1002_16-0" class="reference"><a href="#cite_note-Benson_SC_1002-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Opie_2009_14-1" class="reference"><a href="#cite_note-Opie_2009-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup class="reference nowrap"><span title="Page / location: 171">: 171 </span></sup> As a partial agonist, it activates the receptor by 25–30%. Clinical trials have shown that telmisartan increases insulin sensitivity, reduces cardiac fibrosis and hypertrophy, and improves endothilial function; all these effects can be attributed to its activity on PPAR-γ.<sup id="cite_ref-ayza_17-0" class="reference"><a href="#cite_note-ayza-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> The kidney-protecting activity of telmisartan is attributed to both angiotensin II antagonism and improved endothelial function from PPAR-γ.<sup id="cite_ref-ayza_17-1" class="reference"><a href="#cite_note-ayza-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p><p>Telmisartan's activity at the <a href="/wiki/Peroxisome_proliferator-activated_receptor_delta" title="Peroxisome proliferator-activated receptor delta">peroxisome proliferator-activated receptor delta</a> (PPAR-δ) receptor has prompted speculation around its potential as a sport doping agent as an alternative to <a href="/wiki/GW_501516" class="mw-redirect" title="GW 501516">GW 501516</a>.<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> Telmisartan activates PPAR-δ receptors in several tissues. In mice, this results in effects such as enhanced endurance.<sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> However, telmisartan does not improve the walking performance (6-minute walk distance) in people with <a href="/wiki/Lower_extremity" class="mw-redirect" title="Lower extremity">lower extremity</a> <a href="/wiki/Peripheral_artery_disease" title="Peripheral artery disease">peripheral artery disease</a>.<sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> </p><p>Telmisartan activates PPAR-α <i>in vitro</i>.<sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Pharmacokinetics">Pharmacokinetics</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=7" title="Edit section: Pharmacokinetics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The substance is quickly but to varying degrees absorbed from the gut. The average <a href="/wiki/Bioavailability" title="Bioavailability">bioavailability</a> is about 50% (42–100%). Food intake has no clinically relevant influence on the kinetics of telmisartan. <a href="/wiki/Plasma_protein_binding" title="Plasma protein binding">Plasma protein binding</a> is over 99.5%, mainly to <a href="/wiki/Albumin" title="Albumin">albumin</a> and <a href="/wiki/Alpha-1-acid_glycoprotein" class="mw-redirect" title="Alpha-1-acid glycoprotein">alpha-1-acid glycoprotein</a>.<sup id="cite_ref-AC_15-1" class="reference"><a href="#cite_note-AC-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> It has the longest half-life of any <a href="/wiki/Angiotensin_II_receptor_blocker" title="Angiotensin II receptor blocker">angiotensin II receptor blocker</a> (ARB) (24 hours)<sup id="cite_ref-Pritor_prescribing_information_25-0" class="reference"><a href="#cite_note-Pritor_prescribing_information-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Benson_SC_1002_16-1" class="reference"><a href="#cite_note-Benson_SC_1002-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> and the largest <a href="/wiki/Volume_of_distribution" title="Volume of distribution">volume of distribution</a> among ARBs (500 liters).<sup id="cite_ref-pmid11014323_26-0" class="reference"><a href="#cite_note-pmid11014323-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> Less than 3% of telmisartan is inactivated by <a href="/wiki/Glucuronidation" title="Glucuronidation">glucuronidation</a> in the liver, and over 97% is eliminated in unchanged form via <a href="/wiki/Bile" title="Bile">bile</a> and faeces.<sup id="cite_ref-AHFS2019_6-13" class="reference"><a href="#cite_note-AHFS2019-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-AC_15-2" class="reference"><a href="#cite_note-AC-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="History">History</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=8" title="Edit section: History"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/Discovery_and_development_of_angiotensin_receptor_blockers" title="Discovery and development of angiotensin receptor blockers">Discovery and development of angiotensin receptor blockers</a></div> <div class="mw-heading mw-heading2"><h2 id="Society_and_culture">Society and culture</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=9" title="Edit section: Society and culture"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Telmisartan is available as a <a href="/wiki/Generic_medication" class="mw-redirect" title="Generic medication">generic medication</a>.<sup id="cite_ref-BNF76_8-1" class="reference"><a href="#cite_note-BNF76-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=10" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Telmisartan does not appear effective for slowing the growth of <a href="/wiki/Abdominal_aortic_aneurysm" title="Abdominal aortic aneurysm">abdominal aortic aneurysm</a>.<sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> </p><p>Telmisartan does not cause rapid cancer growth like the PPAR-δ agonist GW 501516, but whether it causes a change in cancer rates is disputed. Short-term use is not associated with an increased incidence of cancer over other ARB drugs, according to a large 2016 analysis of UK patients.<sup id="cite_ref-29" class="reference"><a href="#cite_note-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup> A 2022 meta-analysis finds that a longer duration of taking ARBs (including telmisartan) is associated with an increase in cancer rates. Patients who have taken an ARB for more than 3 years appears 11% more likely to develop cancer.<sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup> A 2023 large-scale study on Lebanese patients finds that taking ARBs reduces the incidence of cancer, with greater effects on those who have taken the drug for a long time. A 2021 Korean study and a 2012 Japanese study finds similar results.<sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=11" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-Preg2019-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-Preg2019_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Preg2019_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Preg2019_1-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Preg2019_1-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.drugs.com/pregnancy/telmisartan.html">"Telmisartan Pregnancy and Breastfeeding Warnings"</a>. <i>Drugs.com</i><span class="reference-accessdate">. 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href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863774">5863774</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/27557862">27557862</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Hypertension&rft.atitle=The+Use+of+Telmisartan+and+the+Incidence+of+Cancer&rft.volume=29&rft.issue=12&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1358-%3C%2Fspan%3E1365&rft.date=2016-12&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5863774%23id-name%3DPMC&rft_id=info%3Apmid%2F27557862&rft_id=info%3Adoi%2F10.1093%2Fajh%2Fhpw095&rft.aulast=Tascilar&rft.aufirst=K&rft.au=Azoulay%2C+L&rft.au=Dell%27Aniello%2C+S&rft.au=Bartels%2C+DB&rft.au=Suissa%2C+S&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5863774&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATelmisartan" class="Z3988"></span></span> </li> <li id="cite_note-30"><span class="mw-cite-backlink"><b><a href="#cite_ref-30">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSipahi2022" class="citation journal cs1">Sipahi I (2022). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890666">"Risk of cancer with angiotensin-receptor blockers increases with increasing cumulative exposure: Meta-regression analysis of randomized trials"</a>. <i>PLOS ONE</i>. <b>17</b> (3): e0263461. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2022PLoSO..1763461S">2022PLoSO..1763461S</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pone.0263461">10.1371/journal.pone.0263461</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890666">8890666</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/35235571">35235571</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+ONE&rft.atitle=Risk+of+cancer+with+angiotensin-receptor+blockers+increases+with+increasing+cumulative+exposure%3A+Meta-regression+analysis+of+randomized+trials&rft.volume=17&rft.issue=3&rft.pages=e0263461&rft.date=2022&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC8890666%23id-name%3DPMC&rft_id=info%3Apmid%2F35235571&rft_id=info%3Adoi%2F10.1371%2Fjournal.pone.0263461&rft_id=info%3Abibcode%2F2022PLoSO..1763461S&rft.aulast=Sipahi&rft.aufirst=I&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC8890666&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATelmisartan" class="Z3988"></span></span> </li> <li id="cite_note-31"><span class="mw-cite-backlink"><b><a href="#cite_ref-31">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFDagherEl_HelouHaifaChalhoub2023" class="citation journal cs1">Dagher YG, El Helou S, Haifa KG, Chalhoub IG, Boulos RT, Atallah B, et al. (September 2023). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489396">"The association between angiotensin receptor blockers and lung, bladder, and colon cancer development: A 10-year multicentric retrospective Lebanese study"</a>. <i>Medicine</i>. <b>102</b> (36): e34901. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2FMD.0000000000034901">10.1097/MD.0000000000034901</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489396">10489396</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/37682163">37682163</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Medicine&rft.atitle=The+association+between+angiotensin+receptor+blockers+and+lung%2C+bladder%2C+and+colon+cancer+development%3A+A+10-year+multicentric+retrospective+Lebanese+study&rft.volume=102&rft.issue=36&rft.pages=e34901&rft.date=2023-09&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10489396%23id-name%3DPMC&rft_id=info%3Apmid%2F37682163&rft_id=info%3Adoi%2F10.1097%2FMD.0000000000034901&rft.aulast=Dagher&rft.aufirst=YG&rft.au=El+Helou%2C+S&rft.au=Haifa%2C+KG&rft.au=Chalhoub%2C+IG&rft.au=Boulos%2C+RT&rft.au=Atallah%2C+B&rft.au=Nasr%2C+F&rft.au=Kassab%2C+I&rft.au=Chahine%2C+MN&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10489396&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATelmisartan" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Telmisartan&action=edit&section=12" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYusufTeoPogueDyal2008" class="citation journal cs1">Yusuf S, Teo KK, Pogue J, Dyal L, Copland I, Schumacher H, et al. (April 2008). "Telmisartan, ramipril, or both in patients at high risk for vascular events". <i>The New England Journal of Medicine</i>. <b>358</b> (15). Massachusetts Medical Society: <span class="nowrap">1547–</span>1559. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1056%2Fnejmoa0801317">10.1056/nejmoa0801317</a>. <a href="/wiki/Hdl_(identifier)" class="mw-redirect" title="Hdl (identifier)">hdl</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://hdl.handle.net/2437%2F81925">2437/81925</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18378520">18378520</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+England+Journal+of+Medicine&rft.atitle=Telmisartan%2C+ramipril%2C+or+both+in+patients+at+high+risk+for+vascular+events&rft.volume=358&rft.issue=15&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1547-%3C%2Fspan%3E1559&rft.date=2008-04&rft_id=info%3Ahdl%2F2437%2F81925&rft_id=info%3Apmid%2F18378520&rft_id=info%3Adoi%2F10.1056%2Fnejmoa0801317&rft.aulast=Yusuf&rft.aufirst=S&rft.au=Teo%2C+KK&rft.au=Pogue%2C+J&rft.au=Dyal%2C+L&rft.au=Copland%2C+I&rft.au=Schumacher%2C+H&rft.au=Dagenais%2C+G&rft.au=Sleight%2C+P&rft.au=Anderson%2C+C&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATelmisartan" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYusufTeoAndersonPogue2008" class="citation journal cs1">Yusuf S, Teo K, Anderson C, Pogue J, Dyal L, Copland I, et al. (September 2008). "Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial". <i>Lancet</i>. <b>372</b> (9644): <span class="nowrap">1174–</span>1183. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0140-6736%2808%2961242-8">10.1016/S0140-6736(08)61242-8</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18757085">18757085</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:5203511">5203511</a>.</cite><span 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id="Antihypertensive_drugs_acting_on_the_renin–angiotensin_system_(C09)651" style="font-size:114%;margin:0 4em"><a href="/wiki/Antihypertensive_drug" class="mw-redirect" title="Antihypertensive drug">Antihypertensive drugs</a> acting on the <a href="/wiki/Renin%E2%80%93angiotensin_system" title="Renin–angiotensin system">renin–angiotensin system</a> (<a href="/wiki/ATC_code_C09" title="ATC code C09">C09</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/ACE_inhibitor" title="ACE inhibitor">ACE inhibitors</a><br />("-pril")</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/ACE_inhibitor#Sulfhydryl-containing_agents" title="ACE inhibitor">Sulfhydryl-containing</a>:</i> <a href="/wiki/Captopril" title="Captopril">Captopril</a></li> <li><a href="/wiki/Rentiapril" title="Rentiapril">Rentiapril</a></li> <li><a href="/wiki/Zofenopril" title="Zofenopril">Zofenopril</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Zofenopril/nebivolol&action=edit&redlink=1" class="new" title="Zofenopril/nebivolol (page does not exist)">+nebivolol</a>)</li> <li><i><a href="/wiki/ACE_inhibitor#Dicarboxylate-containing_agents" title="ACE inhibitor">Dicarboxylate-containing</a>: </i><a href="/wiki/Enalapril" title="Enalapril">Enalapril</a><sup>#</sup> (<a href="/w/index.php?title=Enalapril/lercanidipine&action=edit&redlink=1" class="new" title="Enalapril/lercanidipine (page does not exist)">+lercanidipine</a>, <a href="/w/index.php?title=Enalapril/nitrendipine&action=edit&redlink=1" class="new" title="Enalapril/nitrendipine (page does not exist)">+nitrendipine</a>)</li> <li><a href="/wiki/Benazepril" title="Benazepril">Benazepril</a><span class="nowrap"> </span>(<a href="/wiki/Benazepril/amlodipine" class="mw-redirect" title="Benazepril/amlodipine">+amlodipine</a>, <a href="/w/index.php?title=Benazepril/pimobendan&action=edit&redlink=1" class="new" title="Benazepril/pimobendan (page does not exist)">+pimobendan</a>)</li> <li><a href="/wiki/Cilazapril" title="Cilazapril">Cilazapril</a></li> <li><a href="/wiki/Delapril" title="Delapril">Delapril</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Delapril/manidipine&action=edit&redlink=1" class="new" title="Delapril/manidipine (page does not exist)">+manidipine</a>)</li> <li><a href="/wiki/Imidapril" title="Imidapril">Imidapril</a></li> <li><a href="/wiki/Lisinopril" title="Lisinopril">Lisinopril</a><span class="nowrap"> </span>(<a href="/wiki/Lisinopril/amlodipine" title="Lisinopril/amlodipine">+amlodipine</a>, <a href="/wiki/Lisinopril/hydrochlorothiazide" title="Lisinopril/hydrochlorothiazide">+HCT</a>)</li> <li><a href="/wiki/Moexipril" title="Moexipril">Moexipril</a></li> <li><a href="/wiki/Perindopril" title="Perindopril">Perindopril</a><span class="nowrap"> </span>(<a href="/wiki/Perindopril/amlodipine" class="mw-redirect" title="Perindopril/amlodipine">+amlodipine</a>, <a href="/w/index.php?title=Perindopril/bisoprolol&action=edit&redlink=1" class="new" title="Perindopril/bisoprolol (page does not exist)">+bisoprolol</a>, <a href="/wiki/Perindopril/indapamide" title="Perindopril/indapamide">+indapamide</a>, <a href="/w/index.php?title=Perindopril/amlodipine/indapamide&action=edit&redlink=1" class="new" title="Perindopril/amlodipine/indapamide (page does not exist)">+amlodipine and indapamide</a>, <a href="/w/index.php?title=Perindopril/bisoprolol/amlodipine&action=edit&redlink=1" class="new" title="Perindopril/bisoprolol/amlodipine (page does not exist)">+bisoprolol and amlodipine</a>, <a href="/w/index.php?title=Perindopril/bisoprolol/amlodipine/indapamide&action=edit&redlink=1" class="new" title="Perindopril/bisoprolol/amlodipine/indapamide (page does not exist)">+bisoprolol, amlodipine, and indapamide</a>)</li> <li><a href="/wiki/Quinapril" title="Quinapril">Quinapril</a><span class="nowrap"> </span>(<a href="/wiki/Quinapril/hydrochlorothiazide" class="mw-redirect" title="Quinapril/hydrochlorothiazide">+HCT</a>)</li> <li><a href="/wiki/Ramipril" title="Ramipril">Ramipril</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Ramipril/amlodipine&action=edit&redlink=1" class="new" title="Ramipril/amlodipine (page does not exist)">+amlodipine</a>, <a href="/w/index.php?title=Ramipril/amlodipine/hydrochlorothiazide&action=edit&redlink=1" class="new" title="Ramipril/amlodipine/hydrochlorothiazide (page does not exist)">+amlodipine and HCT</a>, <a href="/w/index.php?title=Ramipril/bisoprolol&action=edit&redlink=1" class="new" title="Ramipril/bisoprolol (page does not exist)">+bisoprolol</a>, <a href="/w/index.php?title=Ramipril/felodipine&action=edit&redlink=1" class="new" title="Ramipril/felodipine (page does not exist)">+felodipine</a>)</li> <li><a href="/wiki/Spirapril" title="Spirapril">Spirapril</a></li> <li><a href="/wiki/Temocapril" title="Temocapril">Temocapril</a></li> <li><a href="/wiki/Trandolapril" title="Trandolapril">Trandolapril</a><span class="nowrap"> </span>(<a href="/wiki/Trandolapril/verapamil" title="Trandolapril/verapamil">+verapamil</a>)</li> <li><i><a href="/wiki/ACE_inhibitor#Phosphonate-containing_agents" title="ACE inhibitor">Phosphonate-containing</a></i>: <a href="/wiki/Ceronapril" title="Ceronapril">Ceronapril</a></li> <li><a href="/wiki/Fosinopril" title="Fosinopril">Fosinopril</a><span class="nowrap"> </span>(<a href="/wiki/Fosinopril/hydrochlorothiazide" class="mw-redirect" title="Fosinopril/hydrochlorothiazide">+HCT</a>)</li> <li><i>Other/ungrouped:</i> <a href="/wiki/Alacepril" title="Alacepril">Alacepril</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Angiotensin_II_receptor_antagonist" class="mw-redirect" title="Angiotensin II receptor antagonist">AIIRAs</a><br />("-sartan")</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Azilsartan" title="Azilsartan">Azilsartan</a></li> <li><a href="/wiki/Candesartan" title="Candesartan">Candesartan</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Candesartan/amlodipine&action=edit&redlink=1" class="new" title="Candesartan/amlodipine (page does not exist)">+amlodipine</a>, <a href="/w/index.php?title=Candesartan/amlodipine/hydrochlorothiazide&action=edit&redlink=1" class="new" title="Candesartan/amlodipine/hydrochlorothiazide (page does not exist)">+amlodipine and HCT</a>)</li> <li><a href="/wiki/Eprosartan" title="Eprosartan">Eprosartan</a></li> <li><a href="/wiki/Fimasartan" title="Fimasartan">Fimasartan</a></li> <li><a href="/wiki/Irbesartan" title="Irbesartan">Irbesartan</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Irbesartan/amlodipine&action=edit&redlink=1" class="new" title="Irbesartan/amlodipine (page does not exist)">+amlodipine</a>, <a href="/w/index.php?title=Irbesartan/amlodipine/hydrochlorothiazide&action=edit&redlink=1" class="new" title="Irbesartan/amlodipine/hydrochlorothiazide (page does not exist)">+amlodipine and HCT</a>, <a href="/wiki/Irbesartan/hydrochlorothiazide" class="mw-redirect" title="Irbesartan/hydrochlorothiazide">+HCT</a>)</li> <li><a href="/wiki/Losartan" title="Losartan">Losartan</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Losartan/amlodipine&action=edit&redlink=1" class="new" title="Losartan/amlodipine (page does not exist)">+amlodipine</a>, <a href="/wiki/Losartan/hydrochlorothiazide" title="Losartan/hydrochlorothiazide">+HCT</a>)</li> <li><a href="/wiki/Olmesartan" title="Olmesartan">Olmesartan</a><span class="nowrap"> </span>(<a href="/wiki/Amlodipine/olmesartan" title="Amlodipine/olmesartan">+amlodipine</a>, <a href="/wiki/Olmesartan/amlodipine/hydrochlorothiazide" title="Olmesartan/amlodipine/hydrochlorothiazide">+amlodipine and HCT</a>, <a href="/wiki/Olmesartan/hydrochlorothiazide" title="Olmesartan/hydrochlorothiazide">+HCT</a>)</li> <li><a href="/wiki/Tasosartan" title="Tasosartan">Tasosartan</a><sup>§</sup></li> <li><a class="mw-selflink selflink">Telmisartan</a><span class="nowrap"> </span>(<a href="/wiki/Telmisartan/amlodipine" title="Telmisartan/amlodipine">+amlodipine</a>, <a href="/w/index.php?title=Telmisartan/amlodipine/hydrochlorothiazide&action=edit&redlink=1" class="new" title="Telmisartan/amlodipine/hydrochlorothiazide (page does not exist)">+amlodipine and HCT</a>, <a href="/wiki/Telmisartan/hydrochlorothiazide" title="Telmisartan/hydrochlorothiazide">+HCT</a>)</li> <li><a href="/wiki/Valsartan" title="Valsartan">Valsartan</a><span class="nowrap"> </span>(<a href="/w/index.php?title=Valsartan/aliskiren&action=edit&redlink=1" class="new" title="Valsartan/aliskiren (page does not exist)">+aliskiren</a>, <a href="/wiki/Amlodipine/valsartan" title="Amlodipine/valsartan">+amlodipine</a>, <a href="/wiki/Amlodipine/valsartan/hydrochlorothiazide" class="mw-redirect" title="Amlodipine/valsartan/hydrochlorothiazide">+amlodipine and HCT</a>, <a href="/wiki/Valsartan/hydrochlorothiazide" title="Valsartan/hydrochlorothiazide">+HCT</a>, <a href="/w/index.php?title=Valsartan/lercanidipine&action=edit&redlink=1" class="new" title="Valsartan/lercanidipine (page does not exist)">+lercanidipine</a>, <a href="/wiki/Nebivolol/valsartan" title="Nebivolol/valsartan">+nebivolol</a>, <a href="/wiki/Sacubitril/valsartan" title="Sacubitril/valsartan">+sacubitril</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Renin_inhibitor" title="Renin inhibitor">Renin inhibitors</a><br />("-kiren")</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aliskiren" title="Aliskiren">Aliskiren</a><span class="nowrap"> </span>(<a href="/wiki/Aliskiren/amlodipine" title="Aliskiren/amlodipine">+amlodipine</a>, <a href="/wiki/Aliskiren/hydrochlorothiazide" title="Aliskiren/hydrochlorothiazide">+HCT</a>, <a href="/wiki/Aliskiren/amlodipine/hydrochlorothiazide" title="Aliskiren/amlodipine/hydrochlorothiazide">+amlodipine and HCT</a>)</li> <li><a href="/wiki/Remikiren" title="Remikiren">Remikiren</a><sup>§</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Dual <a href="/wiki/Angiotensin-converting_enzyme" title="Angiotensin-converting enzyme">ACE</a>/<a href="/wiki/Neprilysin" title="Neprilysin">NEP</a> inhibitors</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Gemopatrilat" title="Gemopatrilat">Gemopatrilat</a></li> <li><a href="/w/index.php?title=Ilepatril&action=edit&redlink=1" class="new" title="Ilepatril (page does not exist)">Ilepatril</a></li> <li><a href="/wiki/Omapatrilat" title="Omapatrilat">Omapatrilat</a></li> <li><a href="/w/index.php?title=Sampatrilat&action=edit&redlink=1" class="new" title="Sampatrilat (page does not exist)">Sampatrilat</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Neprilysin" title="Neprilysin">Neprilysin</a> inhibitors</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sacubitril" title="Sacubitril">Sacubitril</a><span class="nowrap"> </span>(<a href="/wiki/Sacubitril/valsartan" title="Sacubitril/valsartan">+valsartan</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sparsentan" title="Sparsentan">Sparsentan</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Pharmacodynamics105" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e8e8ff;background:#ccccff"><div id="Pharmacodynamics105" style="font-size:114%;margin:0 4em"><a href="/wiki/Pharmacodynamics" title="Pharmacodynamics">Pharmacodynamics</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;font-size:114%"><div style="padding:0px"> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Angiotensin_receptor_modulators469" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Angiotensin_receptor_modulators" title="Template:Angiotensin receptor modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Angiotensin_receptor_modulators" title="Template talk:Angiotensin receptor modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Angiotensin_receptor_modulators" title="Special:EditPage/Template:Angiotensin receptor modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Angiotensin_receptor_modulators469" style="font-size:114%;margin:0 4em"><a href="/wiki/Angiotensin_receptor" class="mw-redirect" title="Angiotensin receptor">Angiotensin receptor</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Angiotensin_receptor" class="mw-redirect" title="Angiotensin receptor"><abbr title="Angiotensin receptor">ATR</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Angiotensin receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/Angiotensin_II" class="mw-redirect" title="Angiotensin II">Angiotensin II</a></li> <li><a href="/wiki/Angiotensin_III" class="mw-redirect" title="Angiotensin III">Angiotensin III</a></li> <li><a href="/wiki/Angiotensin_IV" class="mw-redirect" title="Angiotensin IV">Angiotensin IV</a></li> <li><a href="/wiki/L-163,491" title="L-163,491">L-163,491</a></li> <li><a href="/wiki/Saralasin" title="Saralasin">Saralasin</a></li></ul> <ul><li><i>Antagonists:</i> <a href="/wiki/Abitesartan" title="Abitesartan">Abitesartan</a></li> <li><a href="/wiki/Azilsartan" title="Azilsartan">Azilsartan</a></li> <li><a href="/wiki/Candesartan" title="Candesartan">Candesartan</a></li> <li><a href="/w/index.php?title=Elisartan&action=edit&redlink=1" class="new" title="Elisartan (page does not exist)">Elisartan</a></li> <li><a href="/w/index.php?title=Embusartan&action=edit&redlink=1" class="new" title="Embusartan (page does not exist)">Embusartan</a></li> <li><a href="/wiki/Eprosartan" title="Eprosartan">Eprosartan</a></li> <li><a href="/w/index.php?title=EXP-3174&action=edit&redlink=1" class="new" title="EXP-3174 (page does not exist)">EXP-3174</a></li> <li><a href="/wiki/Fimasartan" title="Fimasartan">Fimasartan</a></li> <li><a href="/wiki/Forasartan" title="Forasartan">Forasartan</a></li> <li><a href="/wiki/Irbesartan" title="Irbesartan">Irbesartan</a></li> <li><a href="/wiki/Losartan" title="Losartan">Losartan</a></li> <li><a href="/w/index.php?title=Milfasartan&action=edit&redlink=1" class="new" title="Milfasartan (page does not exist)">Milfasartan</a></li> <li><a href="/wiki/Olmesartan" title="Olmesartan">Olmesartan</a></li> <li><a href="/w/index.php?title=Olodanrigan&action=edit&redlink=1" class="new" title="Olodanrigan (page does not exist)">Olodanrigan</a></li> <li><a href="/w/index.php?title=PD123319&action=edit&redlink=1" class="new" title="PD123319 (page does not exist)">PD123319</a></li> <li><a href="/w/index.php?title=Pomisartan&action=edit&redlink=1" class="new" title="Pomisartan (page does not exist)">Pomisartan</a></li> <li><a href="/w/index.php?title=Pratosartan&action=edit&redlink=1" class="new" title="Pratosartan (page does not exist)">Pratosartan</a></li> <li><a href="/w/index.php?title=Ripisartan&action=edit&redlink=1" class="new" title="Ripisartan (page does not exist)">Ripisartan</a></li> <li><a href="/w/index.php?title=Saprisartan&action=edit&redlink=1" class="new" title="Saprisartan (page does not exist)">Saprisartan</a></li> <li><a href="/wiki/Sparsentan" title="Sparsentan">Sparsentan</a></li> <li><a href="/wiki/Tasosartan" title="Tasosartan">Tasosartan</a></li> <li><a class="mw-selflink selflink">Telmisartan</a></li> <li><a href="/wiki/Valsartan" title="Valsartan">Valsartan</a></li> <li><a href="/w/index.php?title=Zolasartan&action=edit&redlink=1" class="new" title="Zolasartan (page does not exist)">Zolasartan</a></li></ul> <ul><li><i><abbr title="Angiotensin-converting-enzyme">ACE</abbr> inhibitors:</i> <a href="/wiki/Alacepril" title="Alacepril">Alacepril</a></li> <li><a href="/wiki/Benazepril" title="Benazepril">Benazepril</a></li> <li><a href="/wiki/Captopril" title="Captopril">Captopril</a></li> <li><a href="/wiki/Cilazapril" title="Cilazapril">Cilazapril</a></li> <li><a href="/wiki/Delapril" title="Delapril">Delapril</a></li> <li><a href="/wiki/Enalapril" title="Enalapril">Enalapril</a></li> <li><a href="/wiki/Enalaprilat" title="Enalaprilat">Enalaprilat</a></li> <li><a href="/wiki/Fosinopril" title="Fosinopril">Fosinopril</a></li> <li><a href="/wiki/Gemopatrilat" title="Gemopatrilat">Gemopatrilat</a></li> <li><a href="/wiki/Imidapril" title="Imidapril">Imidapril</a></li> <li><a href="/wiki/Lisinopril" title="Lisinopril">Lisinopril</a></li> <li><a href="/wiki/Moexipril" title="Moexipril">Moexipril</a></li> <li><a href="/wiki/Omapatrilat" title="Omapatrilat">Omapatrilat</a></li> <li><a href="/wiki/Perindopril" title="Perindopril">Perindopril</a></li> <li><a href="/wiki/Quinapril" title="Quinapril">Quinapril</a></li> <li><a href="/wiki/Quinaprilat" title="Quinaprilat">Quinaprilat</a></li> <li><a href="/wiki/Ramipril" title="Ramipril">Ramipril</a></li> <li><a href="/wiki/Rentiapril" title="Rentiapril">Rentiapril</a></li> <li><a href="/wiki/Rescinnamine" title="Rescinnamine">Rescinnamine</a></li> <li><a href="/wiki/Spirapril" title="Spirapril">Spirapril</a></li> <li><a href="/wiki/Spiraprilat" title="Spiraprilat">Spiraprilat</a></li> <li><a href="/wiki/Temocapril" title="Temocapril">Temocapril</a></li> <li><a href="/wiki/Trandolapril" title="Trandolapril">Trandolapril</a></li> <li><a href="/wiki/Zofenopril" title="Zofenopril">Zofenopril</a></li> <li><a href="/wiki/Zofenoprilat" title="Zofenoprilat">Zofenoprilat</a></li></ul> <ul><li><i>Renin inhibitors:</i> <a href="/wiki/Aliskiren" title="Aliskiren">Aliskiren</a></li> <li><a href="/w/index.php?title=Ciprokiren&action=edit&redlink=1" class="new" title="Ciprokiren (page does not exist)">Ciprokiren</a></li> <li><a href="/w/index.php?title=Ditekiren&action=edit&redlink=1" class="new" title="Ditekiren (page does not exist)">Ditekiren</a></li> <li><a href="/w/index.php?title=Enalkiren&action=edit&redlink=1" class="new" title="Enalkiren (page does not exist)">Enalkiren</a></li> <li><a href="/w/index.php?title=Imarikiren&action=edit&redlink=1" class="new" title="Imarikiren (page does not exist)">Imarikiren</a></li> <li><a href="/wiki/Pepstatin" title="Pepstatin">Pepstatin</a></li> <li><a href="/wiki/Remikiren" title="Remikiren">Remikiren</a></li> <li><a href="/w/index.php?title=Terlakiren&action=edit&redlink=1" class="new" title="Terlakiren (page does not exist)">Terlakiren</a></li> <li><a href="/w/index.php?title=Zankiren&action=edit&redlink=1" class="new" title="Zankiren (page does not exist)">Zankiren</a></li></ul> <ul><li><i>Propeptides:</i> <a href="/wiki/Angiotensinogen" class="mw-redirect" title="Angiotensinogen">Angiotensinogen</a></li> <li><a href="/wiki/Angiotensin_I" class="mw-redirect" title="Angiotensin I">Angiotensin I</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><i>Combinations:</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Amlodipine/valsartan" title="Amlodipine/valsartan">Amlodipine/valsartan</a></li> <li><a href="/wiki/Olmesartan/amlodipine" class="mw-redirect" title="Olmesartan/amlodipine">Olmesartan/amlodipine</a></li> <li><a href="/wiki/Olmesartan/amlodipine/hydrochlorothiazide" title="Olmesartan/amlodipine/hydrochlorothiazide">Olmesartan/amlodipine/hydrochlorothiazide</a></li> <li><a href="/wiki/Valsartan/hydrochlorothiazide" title="Valsartan/hydrochlorothiazide">Valsartan/hydrochlorothiazide</a></li> <li><a href="/wiki/Valsartan/hydrochlorothiazide/amlodipine" class="mw-redirect" title="Valsartan/hydrochlorothiazide/amlodipine">Valsartan/hydrochlorothiazide/amlodipine</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="PPARTooltip_Peroxisome_proliferator-activated_receptor_modulators1923" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:PPAR_modulators" title="Template:PPAR modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:PPAR_modulators" title="Template talk:PPAR modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:PPAR_modulators" title="Special:EditPage/Template:PPAR modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="PPARTooltip_Peroxisome_proliferator-activated_receptor_modulators1923" style="font-size:114%;margin:0 4em"><a href="/wiki/Peroxisome_proliferator-activated_receptor" title="Peroxisome proliferator-activated receptor"><abbr title="Peroxisome proliferator-activated receptor">PPAR</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Peroxisome proliferator-activated receptor</span> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Peroxisome_proliferator-activated_receptor_alpha" title="Peroxisome proliferator-activated receptor alpha"><abbr title="Peroxisome proliferator-activated receptor alpha">PPARα</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Peroxisome proliferator-activated receptor alpha</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/15-Hydroxyeicosatetraenoic_acid" title="15-Hydroxyeicosatetraenoic acid">15-HETE</a></li> <li><a href="/w/index.php?title=15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic_acid&action=edit&redlink=1" class="new" title="15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (page does not exist)">15-HpETE</a></li> <li><a href="/wiki/Aleglitazar" title="Aleglitazar">Aleglitazar</a></li> <li><a href="/wiki/Aluminium_clofibrate" title="Aluminium clofibrate">Aluminium clofibrate</a></li> <li><a href="/wiki/Arachidonic_acid" title="Arachidonic acid">Arachidonic acid</a></li> <li><a href="/wiki/Bezafibrate" title="Bezafibrate">Bezafibrate</a></li> <li><a href="/wiki/Chiglitazar" title="Chiglitazar">Chiglitazar</a></li> <li><a href="/wiki/Clofibrate" title="Clofibrate">Clofibrate</a></li> <li><a href="/w/index.php?title=CP-775146&action=edit&redlink=1" class="new" title="CP-775146 (page does not exist)">CP-775146</a></li> <li><a href="/wiki/Daidzein" title="Daidzein">Daidzein</a></li> <li><a href="/wiki/Dehydroepiandrosterone" title="Dehydroepiandrosterone">DHEA</a> (<a href="/wiki/Prasterone" title="Prasterone">prasterone</a>) (in rodents)</li> <li><a href="/wiki/Elafibranor" title="Elafibranor">Elafibranor</a></li> <li><a href="/wiki/Etomoxir" title="Etomoxir">Etomoxir</a></li> <li><a href="/wiki/Fenofibrate" title="Fenofibrate">Fenofibrate</a></li> <li><a href="/wiki/Genistein" title="Genistein">Genistein</a></li> <li><a href="/wiki/Gemfibrozil" title="Gemfibrozil">Gemfibrozil</a></li> <li><a href="/w/index.php?title=GW-7647&action=edit&redlink=1" class="new" title="GW-7647 (page does not exist)">GW-7647</a></li> <li><a href="/wiki/Lanifibranor" title="Lanifibranor">Lanifibranor</a></li> <li><a href="/wiki/Leukotriene_B4" title="Leukotriene B4">Leukotriene B<sub>4</sub></a></li> <li><a href="/w/index.php?title=LG-101506&action=edit&redlink=1" class="new" title="LG-101506 (page does not exist)">LG-101506</a></li> <li><a href="/w/index.php?title=LG-100754&action=edit&redlink=1" class="new" title="LG-100754 (page does not exist)">LG-100754</a></li> <li><a href="/wiki/Lobeglitazone" title="Lobeglitazone">Lobeglitazone</a></li> <li><a href="/wiki/Muraglitazar" title="Muraglitazar">Muraglitazar</a></li> <li><a href="/wiki/Oleylethanolamide" class="mw-redirect" title="Oleylethanolamide">Oleylethanolamide</a></li> <li><a href="/wiki/Palmitoylethanolamide" title="Palmitoylethanolamide">Palmitoylethanolamide</a></li> <li><a href="/wiki/Pemafibrate" title="Pemafibrate">Pemafibrate</a></li> <li><a href="/wiki/Perfluorononanoic_acid" title="Perfluorononanoic acid">Perfluorononanoic acid</a></li> <li><a href="/wiki/Perfluorooctanoic_acid" title="Perfluorooctanoic acid">Perfluorooctanoic acid</a></li> <li><a href="/wiki/Pioglitazone" title="Pioglitazone">Pioglitazone</a></li> <li><a href="/wiki/Saroglitazar" title="Saroglitazar">Saroglitazar</a></li> <li><a href="/wiki/Sodelglitazar" title="Sodelglitazar">Sodelglitazar</a></li> <li><a href="/wiki/Tesaglitazar" title="Tesaglitazar">Tesaglitazar</a></li> <li><a href="/wiki/Tetradecylthioacetic_acid" title="Tetradecylthioacetic acid">Tetradecylthioacetic acid</a></li> <li><a href="/wiki/Troglitazone" title="Troglitazone">Troglitazone</a></li> <li><a href="/w/index.php?title=WY-14643&action=edit&redlink=1" class="new" title="WY-14643 (page does not exist)">WY-14643</a></li></ul> <ul><li><i>Antagonists:</i> <a href="/w/index.php?title=GW-6471&action=edit&redlink=1" class="new" title="GW-6471 (page does not exist)">GW-6471</a></li> <li><a href="/wiki/MK-886" title="MK-886">MK-886</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Peroxisome_proliferator-activated_receptor_delta" title="Peroxisome proliferator-activated receptor delta"><abbr title="Peroxisome proliferator-activated receptor delta">PPARδ</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Peroxisome proliferator-activated receptor delta</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/15-Hydroxyeicosatetraenoic_acid" title="15-Hydroxyeicosatetraenoic acid">15-HETE</a></li> <li><a href="/w/index.php?title=15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic_acid&action=edit&redlink=1" class="new" title="15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (page does not exist)">15-HpETE</a></li> <li><a href="/wiki/Arachidonic_acid" title="Arachidonic acid">Arachidonic acid</a></li> <li><a href="/wiki/Bezafibrate" title="Bezafibrate">Bezafibrate</a></li> <li><a href="/wiki/Daidzein" title="Daidzein">Daidzein</a></li> <li><a href="/wiki/Elafibranor" title="Elafibranor">Elafibranor</a></li> <li><a href="/w/index.php?title=Fonadelpar&action=edit&redlink=1" class="new" title="Fonadelpar (page does not exist)">Fonadelpar</a></li> <li><a href="/wiki/Genistein" title="Genistein">Genistein</a></li> <li><a href="/wiki/GW-0742" class="mw-redirect" title="GW-0742">GW-0742</a></li> <li><a href="/wiki/GW-501516" class="mw-redirect" title="GW-501516">GW-501516</a></li> <li><a href="/w/index.php?title=L-165,041&action=edit&redlink=1" class="new" title="L-165,041 (page does not exist)">L-165,041</a></li> <li><a href="/wiki/Lanifibranor" title="Lanifibranor">Lanifibranor</a></li> <li><a href="/w/index.php?title=LG-101506&action=edit&redlink=1" class="new" title="LG-101506 (page does not exist)">LG-101506</a></li> <li><a href="/wiki/Seladelpar" title="Seladelpar">Seladelpar</a></li> <li><a href="/wiki/Sodelglitazar" title="Sodelglitazar">Sodelglitazar</a></li> <li><a href="/wiki/Tetradecylthioacetic_acid" title="Tetradecylthioacetic acid">Tetradecylthioacetic acid</a></li></ul> <ul><li><i>Antagonists:</i> <a href="/w/index.php?title=FH-535&action=edit&redlink=1" class="new" title="FH-535 (page does not exist)">FH-535</a></li> <li><a href="/w/index.php?title=GSK-0660&action=edit&redlink=1" class="new" title="GSK-0660 (page does not exist)">GSK-0660</a></li> <li><a href="/w/index.php?title=GSK-3787&action=edit&redlink=1" class="new" title="GSK-3787 (page does not exist)">GSK-3787</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Peroxisome_proliferator-activated_receptor_gamma" title="Peroxisome proliferator-activated receptor gamma"><abbr title="Peroxisome proliferator-activated receptor gamma">PPARγ</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Peroxisome proliferator-activated receptor gamma</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/w/index.php?title=5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic_acid&action=edit&redlink=1" class="new" title="5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (page does not exist)">5-Oxo-ETE</a></li> <li><a href="/w/index.php?title=5-Oxo-15-hydroxy-ETE&action=edit&redlink=1" class="new" title="5-Oxo-15-hydroxy-ETE (page does not exist)">5-Oxo-15-hydroxy-ETE</a></li> <li><a href="/wiki/Cyclopentenone_prostaglandins" title="Cyclopentenone prostaglandins">15-Deoxy-Δ<sup>12,14</sup>-prostaglandin J<sub>2</sub></a></li> <li><a href="/wiki/15-Hydroxyeicosatetraenoic_acid" title="15-Hydroxyeicosatetraenoic acid">15-HETE</a></li> <li><a href="/w/index.php?title=15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic_acid&action=edit&redlink=1" class="new" title="15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (page does not exist)">15-HpETE</a></li> <li><a href="/wiki/Aleglitazar" title="Aleglitazar">Aleglitazar</a></li> <li><a href="/wiki/Arachidonic_acid" title="Arachidonic acid">Arachidonic acid</a></li> <li><a href="/w/index.php?title=Balaglitazone&action=edit&redlink=1" class="new" title="Balaglitazone (page does not exist)">Balaglitazone</a></li> <li><a href="/wiki/Berberine" title="Berberine">Berberine</a></li> <li><a href="/wiki/Bezafibrate" title="Bezafibrate">Bezafibrate</a></li> <li><a href="/wiki/Cannabidiol" title="Cannabidiol">Cannabidiol</a></li> <li><a href="/w/index.php?title=Cevoglitazar&action=edit&redlink=1" class="new" title="Cevoglitazar (page does not exist)">Cevoglitazar</a></li> <li><a href="/wiki/Chiglitazar" title="Chiglitazar">Chiglitazar</a></li> <li><a href="/wiki/Ciglitazone" title="Ciglitazone">Ciglitazone</a></li> <li><a href="/wiki/Daidzein" title="Daidzein">Daidzein</a></li> <li><a href="/wiki/Darglitazone" title="Darglitazone">Darglitazone</a></li> <li><a href="/w/index.php?title=Edaglitazone&action=edit&redlink=1" class="new" title="Edaglitazone (page does not exist)">Edaglitazone</a></li> <li><a href="/w/index.php?title=Efatutazone&action=edit&redlink=1" class="new" title="Efatutazone (page does not exist)">Efatutazone</a></li> <li><a href="/wiki/Englitazone" title="Englitazone">Englitazone</a></li> <li><a href="/wiki/Etalocib" title="Etalocib">Etalocib</a></li> <li><a href="/wiki/Farglitazar" title="Farglitazar">Farglitazar</a></li> <li><a href="/wiki/Genistein" title="Genistein">Genistein</a></li> <li><a href="/w/index.php?title=GW-1929&action=edit&redlink=1" class="new" title="GW-1929 (page does not exist)">GW-1929</a></li> <li><a href="/wiki/Ibuprofen" title="Ibuprofen">Ibuprofen</a></li> <li><a href="/w/index.php?title=Imiglitazar&action=edit&redlink=1" class="new" title="Imiglitazar (page does not exist)">Imiglitazar</a></li> <li><a href="/wiki/Indeglitazar" class="mw-redirect" title="Indeglitazar">Indeglitazar</a></li> <li><a href="/wiki/Lanifibranor" title="Lanifibranor">Lanifibranor</a></li> <li><a href="/w/index.php?title=LG-100268&action=edit&redlink=1" class="new" title="LG-100268 (page does not exist)">LG-100268</a></li> <li><a href="/w/index.php?title=LG-100754&action=edit&redlink=1" class="new" title="LG-100754 (page does not exist)">LG-100754</a></li> <li><a href="/w/index.php?title=LG-101506&action=edit&redlink=1" class="new" title="LG-101506 (page does not exist)">LG-101506</a></li> <li><a href="/wiki/Lobeglitazone" title="Lobeglitazone">Lobeglitazone</a></li> <li><a href="/wiki/Muraglitazar" title="Muraglitazar">Muraglitazar (muroglitazar)</a></li> <li><a href="/w/index.php?title=NTZDpa&action=edit&redlink=1" class="new" title="NTZDpa (page does not exist)">nTZDpa</a></li> <li><a href="/w/index.php?title=Naveglitazar&action=edit&redlink=1" class="new" title="Naveglitazar (page does not exist)">Naveglitazar</a></li> <li><a href="/wiki/Netoglitazone" title="Netoglitazone">Netoglitazone</a></li> <li><a href="/w/index.php?title=Oxeglitazar&action=edit&redlink=1" class="new" title="Oxeglitazar (page does not exist)">Oxeglitazar</a></li> <li><a href="/w/index.php?title=Peliglitazar&action=edit&redlink=1" class="new" title="Peliglitazar (page does not exist)">Peliglitazar</a></li> <li><a href="/w/index.php?title=Pemaglitazar&action=edit&redlink=1" class="new" title="Pemaglitazar (page does not exist)">Pemaglitazar</a></li> <li><a href="/wiki/Perfluorononanoic_acid" title="Perfluorononanoic acid">Perfluorononanoic acid</a></li> <li><a href="/wiki/Pioglitazone" title="Pioglitazone">Pioglitazone</a></li> <li><a href="/w/index.php?title=Prostaglandin_J2&action=edit&redlink=1" class="new" title="Prostaglandin J2 (page does not exist)">Prostaglandin J<sub>2</sub></a></li> <li><a href="/w/index.php?title=Ragaglitazar&action=edit&redlink=1" class="new" title="Ragaglitazar (page does not exist)">Ragaglitazar</a></li> <li><a href="/w/index.php?title=Reglitazar&action=edit&redlink=1" class="new" title="Reglitazar (page does not exist)">Reglitazar</a></li> <li><a href="/wiki/Rivoglitazone" title="Rivoglitazone">Rivoglitazone</a></li> <li><a href="/wiki/Rosiglitazone" title="Rosiglitazone">Rosiglitazone</a></li> <li><a href="/w/index.php?title=RS5444&action=edit&redlink=1" class="new" title="RS5444 (page does not exist)">RS5444</a></li> <li><a href="/wiki/Saroglitazar" title="Saroglitazar">Saroglitazar</a></li> <li><a href="/w/index.php?title=Sipoglitazar&action=edit&redlink=1" class="new" title="Sipoglitazar (page does not exist)">Sipoglitazar</a></li> <li><a href="/wiki/Sodelglitazar" title="Sodelglitazar">Sodelglitazar</a></li> <li><a class="mw-selflink selflink">Telmisartan</a></li> <li><a href="/wiki/Tesaglitazar" title="Tesaglitazar">Tesaglitazar</a></li> <li><a href="/wiki/Troglitazone" title="Troglitazone">Troglitazone</a></li></ul> <ul><li><i><a href="/wiki/Selective_PPAR%CE%B3_modulator" class="mw-redirect" title="Selective PPARγ modulator"><abbr title="Selective PPARγ modulator">SPPARMs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Selective PPARγ modulator</span>:</i> <a href="/wiki/Bisphenol_A_diglycidyl_ether" title="Bisphenol A diglycidyl ether">BADGE</a></li> <li><a href="/wiki/EPI-001" title="EPI-001">EPI-001</a></li> <li><a href="/w/index.php?title=INT-131&action=edit&redlink=1" class="new" title="INT-131 (page does not exist)">INT-131</a></li> <li><a href="/w/index.php?title=MK-0533&action=edit&redlink=1" class="new" title="MK-0533 (page does not exist)">MK-0533</a></li> <li><a href="/w/index.php?title=S26948&action=edit&redlink=1" class="new" title="S26948 (page does not exist)">S26948</a></li></ul> <ul><li><i>Antagonists:</i> <a href="/w/index.php?title=FH-535&action=edit&redlink=1" class="new" title="FH-535 (page does not exist)">FH-535</a></li> <li><a href="/w/index.php?title=GW-9662&action=edit&redlink=1" class="new" title="GW-9662 (page does not exist)">GW-9662</a></li> <li><a href="/w/index.php?title=SR-202_(drug)&action=edit&redlink=1" class="new" title="SR-202 (drug) (page does not exist)">SR-202</a></li> <li><a href="/w/index.php?title=T-0070907&action=edit&redlink=1" class="new" title="T-0070907 (page does not exist)">T-0070907</a></li></ul> <ul><li><i>Unknown:</i> <a href="/w/index.php?title=SR-1664&action=edit&redlink=1" class="new" title="SR-1664 (page does not exist)">SR-1664</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Non-selective</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/Ciprofibrate" title="Ciprofibrate">Ciprofibrate</a></li> <li><a href="/wiki/Clinofibrate" title="Clinofibrate">Clinofibrate</a></li> <li><a href="/wiki/Clofibride" title="Clofibride">Clofibride</a></li> <li><a href="/wiki/Englitazone" title="Englitazone">Englitazone</a></li> <li><a href="/wiki/Etofibrate" title="Etofibrate">Etofibrate</a></li> <li><a href="/wiki/Farglitazar" title="Farglitazar">Farglitazar</a></li> <li><a href="/wiki/Netoglitazone" title="Netoglitazone">Netoglitazone</a></li> <li><a href="/wiki/Ronifibrate" title="Ronifibrate">Ronifibrate</a></li> <li><a href="/wiki/Rivoglitazone" title="Rivoglitazone">Rivoglitazone</a></li> <li><a href="/wiki/Simfibrate" title="Simfibrate">Simfibrate</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <dl><dt>See also</dt> <dd><i><a href="/wiki/Template:Receptor_modulators" title="Template:Receptor modulators">Receptor/signaling modulators</a></i></dd></dl> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Xenobiotic-sensing_receptor_modulators953" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Xenobiotic-sensing_receptor_modulators" title="Template:Xenobiotic-sensing receptor modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Xenobiotic-sensing_receptor_modulators" title="Template talk:Xenobiotic-sensing receptor modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Xenobiotic-sensing_receptor_modulators" title="Special:EditPage/Template:Xenobiotic-sensing receptor modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Xenobiotic-sensing_receptor_modulators953" style="font-size:114%;margin:0 4em"><a href="/wiki/Xenobiotic-sensing_receptor" title="Xenobiotic-sensing receptor">Xenobiotic-sensing receptor</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Constitutive_androstane_receptor" title="Constitutive androstane receptor"><abbr title="Constitutive androstane receptor">CAR</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Constitutive androstane receptor</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/w/index.php?title=6,7-Dimethylesculetin&action=edit&redlink=1" class="new" title="6,7-Dimethylesculetin (page does not exist)">6,7-Dimethylesculetin</a></li> <li><a href="/wiki/Amiodarone" title="Amiodarone">Amiodarone</a></li> <li><a href="/wiki/Artemisinin" title="Artemisinin">Artemisinin</a></li> <li><a href="/w/index.php?title=Benfuracarb&action=edit&redlink=1" class="new" title="Benfuracarb (page does not exist)">Benfuracarb</a></li> <li><a href="/wiki/Carbamazepine" title="Carbamazepine">Carbamazepine</a></li> <li><a href="/wiki/Carvedilol" title="Carvedilol">Carvedilol</a></li> <li><a href="/wiki/Chlorpromazine" title="Chlorpromazine">Chlorpromazine</a></li> <li><a href="/wiki/Chrysin" title="Chrysin">Chrysin</a></li> <li><a href="/w/index.php?title=CITCO_(drug)&action=edit&redlink=1" class="new" title="CITCO (drug) (page does not exist)">CITCO</a></li> <li><a href="/wiki/Clotrimazole" title="Clotrimazole">Clotrimazole</a></li> <li><a href="/wiki/Cyclophosphamide" title="Cyclophosphamide">Cyclophosphamide</a></li> <li><a href="/wiki/Cypermethrin" title="Cypermethrin">Cypermethrin</a></li> <li><a href="/wiki/Dehydroepiandrosterone" title="Dehydroepiandrosterone">DHEA</a> (<a href="/wiki/Prasterone" title="Prasterone">prasterone</a>)</li> <li><a href="/wiki/Efavirenz" title="Efavirenz">Efavirenz</a></li> <li><a href="/wiki/Ellagic_acid" title="Ellagic acid">Ellagic acid</a></li> <li><a href="/wiki/Griseofulvin" title="Griseofulvin">Griseofulvin</a></li> <li><a href="/wiki/Methoxychlor" title="Methoxychlor">Methoxychlor</a></li> <li><a href="/wiki/Mifepristone" title="Mifepristone">Mifepristone</a></li> <li><a href="/wiki/Nefazodone" title="Nefazodone">Nefazodone</a></li> <li><a href="/wiki/Nevirapine" title="Nevirapine">Nevirapine</a></li> <li><a href="/wiki/Nicardipine" title="Nicardipine">Nicardipine</a></li> <li><a href="/w/index.php?title=Octicizer&action=edit&redlink=1" class="new" title="Octicizer (page does not exist)">Octicizer</a></li> <li><a href="/wiki/Permethrin" title="Permethrin">Permethrin</a></li> <li><a href="/wiki/Phenobarbital" title="Phenobarbital">Phenobarbital</a></li> <li><a href="/wiki/Phenytoin" title="Phenytoin">Phenytoin</a></li> <li><a href="/wiki/5%CE%B2-Dihydroprogesterone" title="5β-Dihydroprogesterone">Pregnanedione (5β-dihydroprogesterone)</a></li> <li><a href="/wiki/Reserpine" title="Reserpine">Reserpine</a></li> <li><a href="/w/index.php?title=TCPOBOP&action=edit&redlink=1" class="new" title="TCPOBOP (page does not exist)">TCPOBOP</a></li> <li><a class="mw-selflink selflink">Telmisartan</a></li> <li><a href="/wiki/Tolnaftate" title="Tolnaftate">Tolnaftate</a></li> <li><a href="/wiki/Troglitazone" title="Troglitazone">Troglitazone</a></li> <li><a href="/wiki/Valproic_acid" class="mw-redirect" title="Valproic acid">Valproic acid</a></li></ul> <ul><li><i>Antagonists:</i> <a href="/w/index.php?title=3,17%CE%B2-Estradiol&action=edit&redlink=1" class="new" title="3,17β-Estradiol (page does not exist)">3,17β-Estradiol</a></li> <li><a href="/w/index.php?title=5%CE%B1-Androstan-3%CE%B1-ol&action=edit&redlink=1" class="new" title="5α-Androstan-3α-ol (page does not exist)">3α-Androstanol</a></li> <li><a href="/wiki/5%CE%B1-Androst-16-en-3%CE%B1-ol" class="mw-redirect" title="5α-Androst-16-en-3α-ol">3α-Androstenol</a></li> <li><a href="/w/index.php?title=5%CE%B1-Androstan-3%CE%B2-ol&action=edit&redlink=1" class="new" title="5α-Androstan-3β-ol (page does not exist)">3β-Androstanol</a></li> <li><a href="/w/index.php?title=5%CE%B1-Androstan-17-ol&action=edit&redlink=1" class="new" title="5α-Androstan-17-ol (page does not exist)">17-Androstanol</a></li> <li><a href="/wiki/Allyl_isothiocyanate" title="Allyl isothiocyanate">AITC</a></li> <li><a href="/wiki/Ethinylestradiol" title="Ethinylestradiol">Ethinylestradiol</a></li> <li><a href="/wiki/Meclizine" title="Meclizine">Meclizine</a></li> <li><a href="/w/index.php?title=Nigramide_J&action=edit&redlink=1" class="new" title="Nigramide J (page does not exist)">Nigramide J</a></li> <li><a href="/wiki/Okadaic_acid" title="Okadaic acid">Okadaic acid</a></li> <li><a href="/wiki/PK-11195" class="mw-redirect" title="PK-11195">PK-11195</a></li> <li><a href="/w/index.php?title=S-07662&action=edit&redlink=1" class="new" title="S-07662 (page does not exist)">S-07662</a></li> <li><a href="/w/index.php?title=T-0901317&action=edit&redlink=1" class="new" title="T-0901317 (page does not exist)">T-0901317</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Pregnane_X_receptor" title="Pregnane X receptor"><abbr title="Pregnane X receptor">PXR</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Pregnane X receptor</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Agonists:</i> <a href="/wiki/17%CE%B1-Hydroxypregnenolone" title="17α-Hydroxypregnenolone">17α-Hydroxypregnenolone</a></li> <li><a href="/wiki/17%CE%B1-Hydroxyprogesterone" title="17α-Hydroxyprogesterone">17α-Hydroxyprogesterone</a></li> <li><a href="/wiki/%CE%944-Androstenedione" class="mw-redirect" title="Δ4-Androstenedione">Δ<sup>4</sup>-Androstenedione</a></li> <li><a href="/wiki/%CE%945-Androstenediol" class="mw-redirect" title="Δ5-Androstenediol">Δ<sup>5</sup>-Androstenediol</a></li> <li><a href="/wiki/%CE%945-Androstenedione" class="mw-redirect" title="Δ5-Androstenedione">Δ<sup>5</sup>-Androstenedione</a></li> <li><a href="/w/index.php?title=AA-861&action=edit&redlink=1" class="new" title="AA-861 (page does not exist)">AA-861</a></li> <li><a href="/wiki/Allopregnanediol" title="Allopregnanediol">Allopregnanediol</a></li> <li><a href="/wiki/5%CE%B1-Dihydroprogesterone" title="5α-Dihydroprogesterone">Allopregnanedione (5α-dihydroprogesterone)</a></li> <li><a href="/wiki/Allopregnanolone" title="Allopregnanolone">Allopregnanolone (brexanolone)</a></li> <li><a href="/wiki/Alpha-Lipoic_acid" class="mw-redirect" title="Alpha-Lipoic acid">Alpha-Lipoic acid</a></li> <li><a href="/wiki/Ambrisentan" title="Ambrisentan">Ambrisentan</a></li> <li><a href="/wiki/AMI-193" class="mw-redirect" title="AMI-193">AMI-193</a></li> <li><a href="/wiki/Amlodipine_besylate" class="mw-redirect" title="Amlodipine besylate">Amlodipine besylate</a></li> <li><a href="/wiki/Antimycotic" class="mw-redirect" title="Antimycotic">Antimycotics</a></li> <li><a href="/wiki/Artemisinin" title="Artemisinin">Artemisinin</a></li> <li><a href="/wiki/Aurothioglucose" title="Aurothioglucose">Aurothioglucose</a></li> <li><a href="/wiki/Bile_acid" title="Bile acid">Bile acids</a></li> <li><a href="/wiki/Bithionol" title="Bithionol">Bithionol</a></li> <li><a href="/wiki/Bosentan" title="Bosentan">Bosentan</a></li> <li><a href="/w/index.php?title=Bumecaine&action=edit&redlink=1" class="new" title="Bumecaine (page does not exist)">Bumecaine</a></li> <li><a href="/wiki/Cafestol" title="Cafestol">Cafestol</a></li> <li><a href="/wiki/Cephaloridine" title="Cephaloridine">Cephaloridine</a></li> <li><a href="/wiki/Cephradine" class="mw-redirect" title="Cephradine">Cephradine</a></li> <li><a href="/wiki/Chlorpromazine" title="Chlorpromazine">Chlorpromazine</a></li> <li><a href="/wiki/Ciglitazone" title="Ciglitazone">Ciglitazone</a></li> <li><a href="/wiki/Clindamycin" title="Clindamycin">Clindamycin</a></li> <li><a href="/wiki/Clofenvinfos" class="mw-redirect" title="Clofenvinfos">Clofenvinfos</a></li> <li><a href="/wiki/Chloroxine" title="Chloroxine">Chloroxine</a></li> <li><a href="/wiki/Clotrimazole" title="Clotrimazole">Clotrimazole</a></li> <li><a href="/wiki/Colforsin" class="mw-redirect" title="Colforsin">Colforsin</a></li> <li><a href="/wiki/Corticosterone" title="Corticosterone">Corticosterone</a></li> <li><a href="/wiki/Cyclophosphamide" title="Cyclophosphamide">Cyclophosphamide</a></li> <li><a href="/wiki/Cyproterone_acetate" title="Cyproterone acetate">Cyproterone acetate</a></li> <li><a href="/wiki/Demecolcine" title="Demecolcine">Demecolcine</a></li> <li><a href="/wiki/Dexamethasone" title="Dexamethasone">Dexamethasone</a></li> <li><a href="/wiki/Dehydroepiandrosterone" title="Dehydroepiandrosterone">DHEA</a> (<a href="/wiki/Prasterone" title="Prasterone">prasterone</a>)</li> <li><a href="/wiki/Dehydroepiandrosterone_sulfate" title="Dehydroepiandrosterone sulfate">DHEA-S</a> (<a href="/wiki/Prasterone_sulfate" title="Prasterone sulfate">prasterone sulfate</a>)</li> <li><a href="/wiki/Dibunate_sodium" class="mw-redirect" title="Dibunate sodium">Dibunate sodium</a></li> <li><a href="/wiki/Diclazuril" title="Diclazuril">Diclazuril</a></li> <li><a href="/wiki/Dicloxacillin" title="Dicloxacillin">Dicloxacillin</a></li> <li><a href="/wiki/Dimercaprol" title="Dimercaprol">Dimercaprol</a></li> <li><a href="/w/index.php?title=Dinaline&action=edit&redlink=1" class="new" title="Dinaline (page does not exist)">Dinaline</a></li> <li><a href="/wiki/Docetaxel" title="Docetaxel">Docetaxel</a></li> <li><a href="/wiki/Docusate_calcium" class="mw-redirect" title="Docusate calcium">Docusate calcium</a></li> <li><a href="/wiki/Dodecylbenzenesulfonic_acid" class="mw-redirect" title="Dodecylbenzenesulfonic acid">Dodecylbenzenesulfonic acid</a></li> <li><a href="/wiki/Dronabinol" title="Dronabinol">Dronabinol</a></li> <li><a href="/wiki/Droxidopa" title="Droxidopa">Droxidopa</a></li> <li><a href="/wiki/Eburnamonine" class="mw-redirect" title="Eburnamonine">Eburnamonine</a></li> <li><a href="/wiki/Ecopipam" title="Ecopipam">Ecopipam</a></li> <li><a href="/wiki/Enzacamene" title="Enzacamene">Enzacamene</a></li> <li><a href="/wiki/Epothilone_B" class="mw-redirect" title="Epothilone B">Epothilone B</a></li> <li><a href="/wiki/Erythromycin" title="Erythromycin">Erythromycin</a></li> <li><a href="/wiki/Famprofazone" title="Famprofazone">Famprofazone</a></li> <li><a href="/w/index.php?title=Febantel&action=edit&redlink=1" class="new" title="Febantel (page does not exist)">Febantel</a></li> <li><a href="/wiki/Felodipine" title="Felodipine">Felodipine</a></li> <li><a href="/wiki/Fenbendazole" title="Fenbendazole">Fenbendazole</a></li> <li><a href="/wiki/Fentanyl" title="Fentanyl">Fentanyl</a></li> <li><a href="/wiki/Flucloxacillin" title="Flucloxacillin">Flucloxacillin</a></li> <li><a href="/wiki/Fluorometholone" title="Fluorometholone">Fluorometholone</a></li> <li><a href="/wiki/Griseofulvin" title="Griseofulvin">Griseofulvin</a></li> <li><a href="/wiki/Guggulsterone" title="Guggulsterone">Guggulsterone</a></li> <li><a href="/wiki/Haloprogin" title="Haloprogin">Haloprogin</a></li> <li><a href="/wiki/Hetacillin_potassium" class="mw-redirect" title="Hetacillin potassium">Hetacillin potassium</a></li> <li><a href="/wiki/Hyperforin" title="Hyperforin">Hyperforin</a></li> <li><a href="/wiki/Hypericum_perforatum" title="Hypericum perforatum"><i>Hypericum perforatum</i> (St John's wort)</a></li> <li><a href="/wiki/Indinavir_sulfate" class="mw-redirect" title="Indinavir sulfate">Indinavir sulfate</a></li> <li><a href="/wiki/Lasalocid_sodium" class="mw-redirect" title="Lasalocid sodium">Lasalocid sodium</a></li> <li><a href="/wiki/Levothyroxine" title="Levothyroxine">Levothyroxine</a></li> <li>Linolenic acid: <a href="/wiki/%CE%91-Linolenic_acid" title="Α-Linolenic acid">α-Linolenic acid</a> and <a href="/wiki/%CE%93-Linolenic_acid" title="Γ-Linolenic acid">γ-Linolenic acid</a></li> <li><a href="/w/index.php?title=LOE-908&action=edit&redlink=1" class="new" title="LOE-908 (page does not exist)">LOE-908</a></li> <li><a href="/wiki/Loratadine" title="Loratadine">Loratadine</a></li> <li><a href="/wiki/Lovastatin" title="Lovastatin">Lovastatin</a></li> <li><a href="/wiki/Meclizine" title="Meclizine">Meclizine</a></li> <li><a href="/wiki/Metacycline" title="Metacycline">Metacycline</a></li> <li><a href="/wiki/Methylprednisolone" title="Methylprednisolone">Methylprednisolone</a></li> <li><a href="/wiki/Metyrapone" title="Metyrapone">Metyrapone</a></li> <li><a href="/wiki/Mevastatin" title="Mevastatin">Mevastatin</a></li> <li><a href="/wiki/Mifepristone" title="Mifepristone">Mifepristone</a></li> <li><a href="/wiki/Nafcillin" title="Nafcillin">Nafcillin</a></li> <li><a href="/wiki/Nicardipine" title="Nicardipine">Nicardipine</a></li> <li><a href="/wiki/Nicotine" title="Nicotine">Nicotine</a></li> <li><a href="/wiki/Nifedipine" title="Nifedipine">Nifedipine</a></li> <li><a href="/wiki/Nilvadipine" title="Nilvadipine">Nilvadipine</a></li> <li><a href="/wiki/Nisoldipine" title="Nisoldipine">Nisoldipine</a></li> <li><a href="/wiki/Norelgestromin" title="Norelgestromin">Norelgestromin</a></li> <li><a href="/wiki/Omeprazole" title="Omeprazole">Omeprazole</a></li> <li><a href="/wiki/Orlistat" title="Orlistat">Orlistat</a></li> <li><a href="/wiki/Oxatomide" title="Oxatomide">Oxatomide</a></li> <li><a href="/wiki/Paclitaxel" title="Paclitaxel">Paclitaxel</a></li> <li><a href="/wiki/Phenobarbital" title="Phenobarbital">Phenobarbital</a></li> <li><a href="/wiki/Piperine" title="Piperine">Piperine</a></li> <li><a href="/wiki/Plicamycin" title="Plicamycin">Plicamycin</a></li> <li><a href="/wiki/Prednisolone" title="Prednisolone">Prednisolone</a></li> <li><a href="/wiki/Pregnanediol" title="Pregnanediol">Pregnanediol</a></li> <li><a href="/wiki/5%CE%B2-Dihydroprogesterone" title="5β-Dihydroprogesterone">Pregnanedione (5β-dihydroprogesterone)</a></li> <li><a href="/wiki/Pregnanolone" title="Pregnanolone">Pregnanolone</a></li> <li><a href="/wiki/Pregnenolone" title="Pregnenolone">Pregnenolone</a></li> <li><a href="/wiki/Pregnenolone_16%CE%B1-carbonitrile" title="Pregnenolone 16α-carbonitrile">Pregnenolone 16α-carbonitrile</a></li> <li><a href="/wiki/Proadifen" title="Proadifen">Proadifen</a></li> <li><a href="/wiki/Progesterone" title="Progesterone">Progesterone</a></li> <li><a href="/wiki/Quingestrone" title="Quingestrone">Quingestrone</a></li> <li><a href="/wiki/Reserpine" title="Reserpine">Reserpine</a></li> <li><a href="/wiki/Reverse_triiodothyronine" title="Reverse triiodothyronine">Reverse triiodothyronine</a></li> <li><a href="/wiki/Rifampicin" title="Rifampicin">Rifampicin</a></li> <li><a href="/wiki/Rifaximin" title="Rifaximin">Rifaximin</a></li> <li><a href="/wiki/Rimexolone" title="Rimexolone">Rimexolone</a></li> <li><a href="/wiki/Riodipine" title="Riodipine">Riodipine</a></li> <li><a href="/wiki/Ritonavir" title="Ritonavir">Ritonavir</a></li> <li><a href="/wiki/Simvastatin" title="Simvastatin">Simvastatin</a></li> <li><a href="/wiki/Sirolimus" title="Sirolimus">Sirolimus</a></li> <li><a href="/wiki/Spironolactone" title="Spironolactone">Spironolactone</a></li> <li><a href="/wiki/Spiroxatrine" title="Spiroxatrine">Spiroxatrine</a></li> <li><a href="/w/index.php?title=SR-12813&action=edit&redlink=1" class="new" title="SR-12813 (page does not exist)">SR-12813</a></li> <li><a href="/w/index.php?title=Suberoylanilide&action=edit&redlink=1" class="new" title="Suberoylanilide (page does not exist)">Suberoylanilide</a></li> <li><a href="/wiki/Sulfisoxazole" class="mw-redirect" title="Sulfisoxazole">Sulfisoxazole</a></li> <li><a href="/wiki/Suramin" title="Suramin">Suramin</a></li> <li><a href="/wiki/Tacrolimus" title="Tacrolimus">Tacrolimus</a></li> <li><a href="/w/index.php?title=Tenylidone&action=edit&redlink=1" class="new" title="Tenylidone (page does not exist)">Tenylidone</a></li> <li><a href="/wiki/Terconazole" title="Terconazole">Terconazole</a></li> <li><a href="/wiki/Testosterone_isocaproate" title="Testosterone isocaproate">Testosterone isocaproate</a></li> <li><a href="/wiki/Tetracycline" title="Tetracycline">Tetracycline</a></li> <li><a href="/wiki/Thiamylal_sodium" class="mw-redirect" title="Thiamylal sodium">Thiamylal sodium</a></li> <li><a href="/wiki/Thiothixene" class="mw-redirect" title="Thiothixene">Thiothixene</a></li> <li><a href="/wiki/Thonzonium_bromide" title="Thonzonium bromide">Thonzonium bromide</a></li> <li><a href="/wiki/Tianeptine" title="Tianeptine">Tianeptine</a></li> <li><a href="/wiki/Troglitazone" title="Troglitazone">Troglitazone</a></li> <li><a href="/wiki/Troleandomycin" title="Troleandomycin">Troleandomycin</a></li> <li><a href="/w/index.php?title=Tropanyl_3,5-dimethulbenzoate&action=edit&redlink=1" class="new" title="Tropanyl 3,5-dimethulbenzoate (page does not exist)">Tropanyl 3,5-dimethulbenzoate</a></li> <li><a href="/wiki/Zafirlukast" title="Zafirlukast">Zafirlukast</a></li> <li><a href="/wiki/Zeranol" title="Zeranol">Zeranol</a></li></ul> <ul><li><i>Antagonists:</i> <a href="/wiki/Ketoconazole" title="Ketoconazole">Ketoconazole</a></li> <li><a href="/wiki/Sesamin" title="Sesamin">Sesamin</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <dl><dt>See also</dt> <dd><i><a href="/wiki/Template:Receptor_modulators" title="Template:Receptor modulators">Receptor/signaling modulators</a></i></dd></dl> 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