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Search results for: out of hospital cardiac
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2639</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: out of hospital cardiac</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2549</span> Honey Intoxication: A Unique Cause of Sudden Cardiac Collapse</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bharat%20Rawat">Bharat Rawat</a>, <a href="https://publications.waset.org/abstracts/search?q=Shekhar%20Rajbhandari"> Shekhar Rajbhandari</a>, <a href="https://publications.waset.org/abstracts/search?q=Yadav%20Bhatta"> Yadav Bhatta</a>, <a href="https://publications.waset.org/abstracts/search?q=Jay%20Prakash%20Jaiswal"> Jay Prakash Jaiswal</a>, <a href="https://publications.waset.org/abstracts/search?q=Shivaji%20Bikram%20Silwal"> Shivaji Bikram Silwal</a>, <a href="https://publications.waset.org/abstracts/search?q=Rajiv%20Shrestha"> Rajiv Shrestha</a>, <a href="https://publications.waset.org/abstracts/search?q=Shova%20Sunuwar"> Shova Sunuwar </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The honey produced by the bees fed on Rhobdodendron species containing grayanotoxin is known as mad honey. Grayanotoxin is found in honey obtained from the nectar of Rhododendron species growing on the mountains of the Black Sea region of Turkey and also in Japan, Nepal, Brazil, parts of North America, and Europe. Although the incidence of grayanotoxin poisoning is rare, there is concern that the number of cases per year will rise with the increasing demand for organic products. Mad honey intoxication might present with mild symptoms of cardiovascular, gastrointestinal and neurological systems or might also present with a life-threatening form with AV block and cardiovascular collapse. In this article, we describe the summary of five cases, which came to our hospital with mad honey related cardiac complications. Findings: In last one year, five cases presented in the emergency department with sudden onset of Loss of consciousness, dizziness, shortness of breath. They felt difficulty after the consumption of 1-3 teaspoonful of wild honey. The honey was brought from most of the rural parts of Nepal like khotang. Some of them also came with vomiting, dizziness, and loose stool. On examination, most of them had severe bradycardia and low blood pressure. No abnormalities were detected on systemic examinations. In one patient, ECG and cardiac enzymes showed features of the acute coronary syndrome, but his treadmill test done few days later was normal. All patients were managed with inj. Atropine, I/V normal saline, and other supportive measures and discharged in a stable condition within one or two days. Conclusions: Rhododendrons is the national flower of Nepal. The specific species of rhododendron found in Nepal which contains the toxin is not known. Bees feeding on these rhododendrons are known to transfer the grayanotoxin to the honey they produce. Most symptoms are mild and resolve themselves without medical intervention. Signs and symptoms of grayanotoxin poisoning rarely last more than 24 hours and are usually not fatal. Some signs of mad honey poisoning include Bradycardia, Cardiac arrhythmia, Hypotension, Nausea and Vomiting. They respond to close monitoring and appropriate supportive treatment. Normally, patients recover completely with no residual damage to the heart or its conduction system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=rhobdodendron" title="rhobdodendron">rhobdodendron</a>, <a href="https://publications.waset.org/abstracts/search?q=honey" title=" honey"> honey</a>, <a href="https://publications.waset.org/abstracts/search?q=grayanotoxin" title=" grayanotoxin"> grayanotoxin</a>, <a href="https://publications.waset.org/abstracts/search?q=bradycardia" title=" bradycardia"> bradycardia</a> </p> <a href="https://publications.waset.org/abstracts/31998/honey-intoxication-a-unique-cause-of-sudden-cardiac-collapse" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31998.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">348</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2548</span> A New Mechanical Architecture Design of a Multifunctional Bed for Bedridden Healthcare</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rogelio%20Portillo%20V%C3%A9lez">Rogelio Portillo Vélez</a>, <a href="https://publications.waset.org/abstracts/search?q=Eduardo%20V%C3%A1zquez-Santacruz"> Eduardo Vázquez-Santacruz</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariano%20Gamboa-Z%C3%BA%C3%B1iga"> Mariano Gamboa-Zúñiga</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper a new mechanical architecture design of a multi functional robot bed, is presented. The importance of this design relies on the fact that in next years the need of assistive devices development will increase in such way that elderly patients will use this kind of devices. This mechanical design implies following specific mechanisms which attend Mexican hospital requirements. This design is the base of next step of this kind of development given that it shows all technical details of the mechanical systems which are needed in order to construct the bed. This is first hospital bed design which could responds to the Latin America hospital requirements. We have obtained these hospital requirements using our diagnosis methodology [14]. From these results we have designed the mechanical system. This is the mechanical base of the hospital robotic bed which is being developed in our robotics laboratory. It will be useful in different hospital environments for elderly and disabled patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=assistive%20robotics" title="assistive robotics">assistive robotics</a>, <a href="https://publications.waset.org/abstracts/search?q=methodology" title=" methodology"> methodology</a>, <a href="https://publications.waset.org/abstracts/search?q=feasibility%20analysis" title=" feasibility analysis"> feasibility analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=robotics" title=" robotics"> robotics</a>, <a href="https://publications.waset.org/abstracts/search?q=operational%20feasibility" title=" operational feasibility"> operational feasibility</a>, <a href="https://publications.waset.org/abstracts/search?q=assistive%20technology" title=" assistive technology"> assistive technology</a>, <a href="https://publications.waset.org/abstracts/search?q=viability%20analysis%20matrix" title=" viability analysis matrix"> viability analysis matrix</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20impact" title=" social impact"> social impact</a> </p> <a href="https://publications.waset.org/abstracts/31590/a-new-mechanical-architecture-design-of-a-multifunctional-bed-for-bedridden-healthcare" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31590.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">397</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2547</span> Young Female’s Heart Was Bitten by Unknown Ghost (Isolated Cardiac Sarcoidosis): A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Heru%20Al%20Amin">Heru Al Amin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sarcoidosis is a granulomatous inflammatory disorder of unclear etiology that can affect multiple different organ systems. Isolated cardiac sarcoidosis is a very rare condition that causes lethal arrhythmia and heart failure. A definite diagnosis of cardiac sarcoidosis remains challenging. The use of multimodality imaging plays a pivotal role in the diagnosis of this entity. Case summary: In this report, we discuss a case of a 50-year-old woman who presented with recurrent palpitation, dizziness, vertigo and presyncope. Electrocardiogram revealed variable heart blocks, including first-degree AV block, second-degree AV block, high-degree AV block, complete AV block, trifascicular block and sometimes supraventricular arrhythmia. Twenty-four hours of Holter monitoring show atrial bigeminy, first-degree AV block and trifascicular block. Transthoracic echocardiography showed Thinning of basal anteroseptal and inferred septum with LV dilatation with reduction of Global Longitudinal Strain. A dual-chamber pacemaker was implanted. CT Coronary angiogram showed no coronary artery disease. Cardiac magnetic resonance revealed basal anteroseptal and inferior septum thinning with focal edema with LGE suggestive of sarcoidosis. Computed tomography of the chest showed no lymphadenopathy or pulmonary infiltration. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) of the whole body showed. We started steroids and followed up with the patient. Conclusion: This case serves to highlight the challenges in identifying and managing isolated CS in a young patient with recurrent syncope with variable heart block. Early, even late initiation of steroids can improve arrhythmia as well as left ventricular function. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20sarcoidosis" title="cardiac sarcoidosis">cardiac sarcoidosis</a>, <a href="https://publications.waset.org/abstracts/search?q=conduction%20abnormality" title=" conduction abnormality"> conduction abnormality</a>, <a href="https://publications.waset.org/abstracts/search?q=syncope" title=" syncope"> syncope</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20MRI" title=" cardiac MRI"> cardiac MRI</a> </p> <a href="https://publications.waset.org/abstracts/157363/young-females-heart-was-bitten-by-unknown-ghost-isolated-cardiac-sarcoidosis-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/157363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">91</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2546</span> Prospective Study to Determine the Efficacy of Day Hospital Care to Improve Treatment Adherence for Hospitalized Schizophrenic Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jin%20Hun%20Choi">Jin Hun Choi</a>, <a href="https://publications.waset.org/abstracts/search?q=So%20Hyun%20Ahn"> So Hyun Ahn</a>, <a href="https://publications.waset.org/abstracts/search?q=Seong%20Keun%20Wang"> Seong Keun Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Ik-Seung%20Chee"> Ik-Seung Chee</a>, <a href="https://publications.waset.org/abstracts/search?q=Jung%20Lan%20Kim"> Jung Lan Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Sun%20Woo%20Lee"> Sun Woo Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The purpose of the study is to investigate the effects of day hospital care in hospitalized schizophrenic patients in terms of treatment adherence and treatment outcomes. Methods: Among schizophrenic patients hospitalized between 2011 and 2012, 23 day hospital care patient and 40 control subjects were included in the study. All candidates underwent Beck Cognitive Insight Scale, Drug Attitude Inventory, World Health Organization Quality of Life Assessment and Psychological Well-Being Scale when their symptoms were stabilized during hospitalization, and after being discharged, 23 patients received day hospital care for two months and then changed to out-patient care while 40 patients received out-patient care immediately after discharge. At the point of two months of out-patient care, the treatment adherence of the two groups was evaluated; tracking observation was performed until February, 2013, and survival rates were compared between the two groups. Results: Treatment adherence was higher in the day hospital care group than in the control group. Kaplan-Meier survival analysis showed a higher survival rate for the day hospital care group compared to the control group. Levels of cognitive insight and quality of life were higher after day hospital care than before day hospital care in the day hospital care group. Conclusions: Through the study, it was confirmed that when hospitalized schizophrenic patients received continuous day hospital care after being discharged, they received further out-patient care more faithfully. The study is considered to aid in the understanding regarding schizophrenic patients’ treatment adherence issues and improvement of treatment outcomes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=schizophrenia" title="schizophrenia">schizophrenia</a>, <a href="https://publications.waset.org/abstracts/search?q=day%20hospital%20care" title=" day hospital care"> day hospital care</a>, <a href="https://publications.waset.org/abstracts/search?q=adherence" title=" adherence"> adherence</a>, <a href="https://publications.waset.org/abstracts/search?q=outcomes" title=" outcomes"> outcomes</a> </p> <a href="https://publications.waset.org/abstracts/54839/prospective-study-to-determine-the-efficacy-of-day-hospital-care-to-improve-treatment-adherence-for-hospitalized-schizophrenic-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54839.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">353</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2545</span> Different Types of Amyloidosis Revealed with Positive Cardiac Scintigraphy with Tc-99M DPD-SPECT</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ioannis%20Panagiotopoulos">Ioannis Panagiotopoulos</a>, <a href="https://publications.waset.org/abstracts/search?q=Efstathios%20Kastritis"> Efstathios Kastritis</a>, <a href="https://publications.waset.org/abstracts/search?q=Anastasia%20Katinioti"> Anastasia Katinioti</a>, <a href="https://publications.waset.org/abstracts/search?q=Georgios%20Efthymiadis"> Georgios Efthymiadis</a>, <a href="https://publications.waset.org/abstracts/search?q=Argyrios%20Doumas"> Argyrios Doumas</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Koutelou"> Maria Koutelou</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Transthyretin amyloidosis (ATTR) is a rare but serious infiltrative disease. Myocardial scintigraphy with DPD has emerged as the most effective, non-invasive, highly sensitive, and highly specific diagnostic method for cardiac ATTR amyloidosis. However, there are cases in which additional laboratory investigations reveal AL amyloidosis or other diseases despite a positive DPD scintigraphy. We describe the experience from the Onassis Cardiac Surgery Center and the monitoring center for infiltrative myocardial diseases of the cardiology clinic at AHEPA. Materials and Methods: All patients with clinical suspicion of cardiac or extracardiac amyloidosis undergo a myocardial scintigraphy scan with Tc-99m DPD. In this way, over 500 patients have been examined. Further diagnostic approach based on clinical and imaging findings includes laboratory investigation and invasive techniques (e.g., biopsy). Results: Out of 76 patients in total with positive myocardial scintigraphy Grade 2 or 3 according to the Perugini scale, 8 were proven to suffer from AL Amyloidosis during the investigation of paraproteinemia. Among these patients, 3 showed Grade 3 uptake, while the rest were graded as Grade 2, or 2 to 3. Additionally, one patient presented diffuse and unusual radiopharmaceutical uptake in soft tissues throughout the body without cardiac involvement. These findings raised suspicions, leading to the analysis of κ and λ light chains in the serum, as well as immunostaining of proteins in the serum and urine of these specific patients. The final diagnosis was AL amyloidosis. Conclusion: The value of DPD scintigraphy in the diagnosis of cardiac amyloidosis from transthyretin is undisputed. However, positive myocardial scintigraphy with DPD should not automatically lead to the diagnosis of ATTR amyloidosis. Laboratory differentiation between ATTR and AL amyloidosis is crucial, as both prognosis and therapeutic strategy are dramatically altered. Laboratory exclusion of paraproteinemia is a necessary and essential step in the diagnostic algorithm of ATTR amyloidosis for all positive myocardial scintigraphy with diphosphonate tracers since >20% of patients with Grade 3 and 2 uptake may conceal AL amyloidosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AL%20amyloidosis" title="AL amyloidosis">AL amyloidosis</a>, <a href="https://publications.waset.org/abstracts/search?q=amyloidosis" title=" amyloidosis"> amyloidosis</a>, <a href="https://publications.waset.org/abstracts/search?q=ATTR" title=" ATTR"> ATTR</a>, <a href="https://publications.waset.org/abstracts/search?q=myocardial%20scintigraphy" title=" myocardial scintigraphy"> myocardial scintigraphy</a>, <a href="https://publications.waset.org/abstracts/search?q=Tc-99m%20DPD" title=" Tc-99m DPD"> Tc-99m DPD</a> </p> <a href="https://publications.waset.org/abstracts/176715/different-types-of-amyloidosis-revealed-with-positive-cardiac-scintigraphy-with-tc-99m-dpd-spect" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/176715.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">81</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2544</span> The Effect of Elapsed Time on the Cardiac Troponin-T Degradation and Its Utility as a Time Since Death Marker in Cases of Death Due to Burn</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sachil%20Kumar">Sachil Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Anoop%20K.Verma"> Anoop K.Verma</a>, <a href="https://publications.waset.org/abstracts/search?q=Uma%20Shankar%20Singh"> Uma Shankar Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It’s extremely important to study postmortem interval in different causes of death since it assists in a great way in making an opinion on the exact cause of death following such incident often times. With diligent knowledge of the interval one could really say as an expert that the cause of death is not feigned hence there is a great need in evaluating such death to have been at the CRIME SCENE before performing an autopsy on such body. The approach described here is based on analyzing the degradation or proteolysis of a cardiac protein in cases of deaths due to burn as a marker of time since death. Cardiac tissue samples were collected from (n=6) medico-legal autopsies, (Department of Forensic Medicine and Toxicology), King George’s Medical University, Lucknow India, after informed consent from the relatives and studied post-mortem degradation by incubation of the cardiac tissue at room temperature (20±2 OC) for different time periods (~7.30, 18.20, 30.30, 41.20, 41.40, 54.30, 65.20, and 88.40 Hours). The cases included were the subjects of burn without any prior history of disease who died in the hospital and their exact time of death was known. The analysis involved extraction of the protein, separation by denaturing gel electrophoresis (SDS-PAGE) and visualization by Western blot using cTnT specific monoclonal antibodies. The area of the bands within a lane was quantified by scanning and digitizing the image using Gel Doc. As time postmortem progresses the intact cTnT band degrades to fragments that are easily detected by the monoclonal antibodies. A decreasing trend in the level of cTnT (% of intact) was found as the PM hours increased. A significant difference was observed between <15 h and other PM hours (p<0.01). Significant difference in cTnT level (% of intact) was also observed between 16-25 h and 56-65 h & >75 h (p<0.01). Western blot data clearly showed the intact protein at 42 kDa, three major (28 kDa, 30kDa, 10kDa) fragments, three additional minor fragments (12 kDa, 14kDa, and 15 kDa) and formation of low molecular weight fragments. Overall, both PMI and cardiac tissue of burned corpse had a statistically significant effect where the greatest amount of protein breakdown was observed within the first 41.40 Hrs and after it intact protein slowly disappears. If the percent intact cTnT is calculated from the total area integrated within a Western blot lane, then the percent intact cTnT shows a pseudo-first order relationship when plotted against the time postmortem. A strong significant positive correlation was found between cTnT and PM hours (r=0.87, p=0.0001). The regression analysis showed a good variability explained (R2=0.768) The post-mortem Troponin-T fragmentation observed in this study reveals a sequential, time-dependent process with the potential for use as a predictor of PMI in cases of burning. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=burn" title="burn">burn</a>, <a href="https://publications.waset.org/abstracts/search?q=degradation" title=" degradation"> degradation</a>, <a href="https://publications.waset.org/abstracts/search?q=postmortem%20interval" title=" postmortem interval"> postmortem interval</a>, <a href="https://publications.waset.org/abstracts/search?q=troponin-T" title=" troponin-T"> troponin-T</a> </p> <a href="https://publications.waset.org/abstracts/30422/the-effect-of-elapsed-time-on-the-cardiac-troponin-t-degradation-and-its-utility-as-a-time-since-death-marker-in-cases-of-death-due-to-burn" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30422.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">449</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2543</span> The Estimation of Human Vital Signs Complexity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20Bikulciene">L. Bikulciene</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Venskaityte"> E. Venskaityte</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Jarusevicius"> G. Jarusevicius</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Non-stationary and nonlinear signals generated by living complex systems defy traditional mechanistic approaches, which are based on homeostasis. Previous our studies have shown that the evaluation of the interactions of physiological signals by using special analysis methods is suitable for observation of physiological processes. It is demonstrated the possibility of using deep physiological model, based interpretation of the changes of the human body’s functional states combined with an application of the analytical method based on matrix theory for the physiological signals analysis, which was applied on high risk cardiac patients. It is shown that evaluation of cardiac signals interactions show peculiar for each individual functional changes at the onset of hemodynamic restoration procedure. Therefore we suggest that the alterations of functional state of the body, after patients overcome surgery can be complemented by the data received from the suggested approach of the evaluation of functional variables interactions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20diseases" title="cardiac diseases">cardiac diseases</a>, <a href="https://publications.waset.org/abstracts/search?q=complex%20systems%20theory" title=" complex systems theory"> complex systems theory</a>, <a href="https://publications.waset.org/abstracts/search?q=ECG%20analysis" title=" ECG analysis"> ECG analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=matrix%20analysis" title=" matrix analysis"> matrix analysis</a> </p> <a href="https://publications.waset.org/abstracts/1511/the-estimation-of-human-vital-signs-complexity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1511.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">344</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2542</span> Complex Management of Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fahad%20Almehmadi">Fahad Almehmadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdullah%20Alrajhi"> Abdullah Alrajhi</a>, <a href="https://publications.waset.org/abstracts/search?q=Bader%20K.%20Alaslab"> Bader K. Alaslab</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdullah%20A.%20Al%20Qurashi"> Abdullah A. Al Qurashi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hattan%20A.%20Hassani"> Hattan A. Hassani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) is an uncommon, inheritable cardiac disorder characterized by the progressive substitution of cardiac myocytes by fibro-fatty tissues. This pathologic substitution predisposes patients to ventricular arrhythmias and right ventricular failure. The underlying genetic defect predominantly involves genes encoding for desmosome proteins, particularly plakophilin-2 (PKP2). These aberrations lead to impaired cell adhesion, heightening the susceptibility to fibrofatty scarring under conditions of mechanical stress. Primarily, ARVD/C affects the right ventricle, but it can also compromise the left ventricle, potentially leading to biventricular heart failure. Clinical presentations can vary, spanning from asymptomatic individuals to those experiencing palpitations, syncopal episodes, and, in severe instances, sudden cardiac death. The establishment of a diagnostic criterion specifically tailored for ARVD/C significantly aids in its accurate diagnosis. Nevertheless, the task of early diagnosis is complicated by the disease's frequently asymptomatic initial stages, and the overall rarity of ARVD/C cases reported globally. In some cases, as exemplified by the adult female patient in this report, the disease may advance to terminal stages, rendering therapies like Ventricular Tachycardia (VT) ablation ineffective. This case underlines the necessity for increased awareness and understanding of ARVD/C to aid in its early detection and management. Through such efforts, we aim to decrease morbidity and mortality associated with this challenging cardiac disorder. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ARVD%2FC" title="ARVD/C">ARVD/C</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiology" title=" cardiology"> cardiology</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20cardiology" title=" interventional cardiology"> interventional cardiology</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20electrophysiology" title=" cardiac electrophysiology"> cardiac electrophysiology</a> </p> <a href="https://publications.waset.org/abstracts/175931/complex-management-of-arrhythmogenic-right-ventricular-dysplasiacardiomyopathy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/175931.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">63</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2541</span> Modern Cardiac Surgical Outcomes in Nonagenarians: A Multicentre Retrospective Observational Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Laurence%20Weinberg">Laurence Weinberg</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominic%20Walpole"> Dominic Walpole</a>, <a href="https://publications.waset.org/abstracts/search?q=Dong-Kyu%20Lee"> Dong-Kyu Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20D%E2%80%99Silva"> Michael D’Silva</a>, <a href="https://publications.waset.org/abstracts/search?q=Jian%20W.%20Chan"> Jian W. Chan</a>, <a href="https://publications.waset.org/abstracts/search?q=Lachlan%20F.%20Miles"> Lachlan F. Miles</a>, <a href="https://publications.waset.org/abstracts/search?q=Bradley%20Carp"> Bradley Carp</a>, <a href="https://publications.waset.org/abstracts/search?q=Adam%20Wells"> Adam Wells</a>, <a href="https://publications.waset.org/abstracts/search?q=Tuck%20S.%20Ngun"> Tuck S. Ngun</a>, <a href="https://publications.waset.org/abstracts/search?q=Siven%20Seevanayagam"> Siven Seevanayagam</a>, <a href="https://publications.waset.org/abstracts/search?q=George%20Matalanis"> George Matalanis</a>, <a href="https://publications.waset.org/abstracts/search?q=Ziauddin%20Ansari"> Ziauddin Ansari</a>, <a href="https://publications.waset.org/abstracts/search?q=Rinaldo%20Bellomo"> Rinaldo Bellomo</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Yii"> Michael Yii</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: There have been multiple recent advancements in the selection, optimization and management of cardiac surgical patients. However, there is limited data regarding the outcomes of nonagenarians undergoing cardiac surgery, despite this vulnerable cohort increasingly receiving these interventions. This study describes the patient characteristics, management and outcomes of a group of nonagenarians undergoing cardiac surgery in the context of contemporary peri-operative care. Methods: A retrospective observational study was conducted of patients 90 to 99 years of age (i.e., nonagenarians) who had undergone cardiac surgery requiring a classic median sternotomy (i.e., open-heart surgery). All operative indications were included. Patients who underwent minimally invasive surgery, transcatheter aortic valve implantation and thoracic aorta surgery were excluded. Data were collected from four hospitals in Victoria, Australia, over an 8-year period (January 2012 – December 2019). The primary objective was to assess six-month mortality in nonagenarians undergoing open-heart surgery and to evaluate the incidence and severity of postoperative complications using the Clavien-Dindo classification system. The secondary objective was to provide a detailed description of the characteristics and peri-operative management of this group. Results: A total of 12,358 adult patients underwent cardiac surgery at the study centers during the observation period, of whom 18 nonagenarians (0.15%) fulfilled the inclusion criteria. The median (IQR) [min-max] age was 91 years (90.0:91.8) [90-94] and 14 patients (78%) were men. Cardiovascular comorbidities, polypharmacy and frailty, were common. The median (IQR) predicted in-hospital mortality by EuroSCORE II was 6.1% (4.1-14.5). All patients were optimized preoperatively by a multidisciplinary team of surgeons, cardiologists, geriatricians and anesthetists. All index surgeries were performed on cardiopulmonary bypass. Isolated coronary artery bypass grafting (CABG) and CABG with aortic valve replacement were the most common surgeries being performed in four and five patients, respectively. Half the study group underwent surgery involving two or more major procedures (e.g. CABG and valve replacement). Surgery was undertaken emergently in 44% of patients. All patients except one experienced at least one postoperative complication. The most common complications were acute kidney injury (72%), new atrial fibrillation (44%) and delirium (39%). The highest Clavien-Dindo complication grade was IIIb occurring once each in three patients. Clavien-Dindo grade IIIa complications occurred in only one patient. The median (IQR) postoperative length of stay was 11.6 days (9.8:17.6). One patient was discharged home and all others to an inpatient rehabilitation facility. Three patients had an unplanned readmission within 30 days of discharge. All patients had follow-up to at least six months after surgery and mortality over this period was zero. The median (IQR) duration of follow-up was 11.3 months (6.0:26.4) and there were no cases of mortality observed within the available follow-up records. Conclusion: In this group of nonagenarians undergoing cardiac surgery, postoperative six-month mortality was zero. Complications were common but generally of low severity. These findings support carefully selected nonagenarian patients being offered cardiac surgery in the context of contemporary, multidisciplinary perioperative care. Further, studies are needed to assess longer-term mortality and functional and quality of life outcomes in this vulnerable surgical cohort. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20surgery" title="cardiac surgery">cardiac surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=mortality" title=" mortality"> mortality</a>, <a href="https://publications.waset.org/abstracts/search?q=nonagenarians" title=" nonagenarians"> nonagenarians</a>, <a href="https://publications.waset.org/abstracts/search?q=postoperative%20complications" title=" postoperative complications"> postoperative complications</a> </p> <a href="https://publications.waset.org/abstracts/148344/modern-cardiac-surgical-outcomes-in-nonagenarians-a-multicentre-retrospective-observational-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/148344.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">119</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2540</span> The Effect of 6 Weeks Endurance Swimming Training on Blood Glucose and Cardiac Tissue Antioxidants in Diabetic Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kh.%20Dehkordi">Kh. Dehkordi</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Sharifi%20Gholam"> R. Sharifi Gholam</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Arshadi"> S. Arshadi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: Oxidative stress is produced under diabetic conditions and possibly causes various forms of tissue damage inpatients with diabetes. Antioxidants defend against the harmful effect of free radicals, which are associated with heart disease, cancer, arthritis, aging and many other diseases1). Antioxidants are very stable molecules capable of neutralizing free radicals by donating an electron to them.The aim of this study was to examine the effect of swimming training, fenugreek seed extract and glibenclamide on plasma glucose and cardiac antioxidants activity in diabetic rats. Design: For this purpose, fifty male wistar rats were divided into five groups, two groups of control rats (diabetic control [DC] and healthy control [HC]), one group of endurance swimming training (EST), one group of fenugreek seed extract highdose (F1, 1.74 g/kg b.w), one group of fenugreek seed extract middle dose (F2, 0.87 g/kg b.w), one group of glibenclamide (G, 0.5 mg/kg b.w). Materials and Methods: Diabetes induced by streptozotocine (STZ), data was analyzed using the one-way ANOVA followed by a Tukey test. Significance level was 0.05. Results: All of the groups' exception of HC showed significant decrease in body weight (P < 0.05), but the diabetic control and swimming training group exhibited a more decrease. All of the groups have shown a significant decrease in plasma glucose than DC group (P < 0.05) but this reduction was more in G group than DC no HC group. S, G and HC groups have shown significant increase in cardiac antioxidant than DC group (P < 0.05) but there wasn't significant difference in other groups (P > 0.05). Conclusion: The present results indicate that regular swimming training lead to decrease in plasma glucose and enhanced cardiac antioxidants in diabetic rats. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=swimming" title="swimming">swimming</a>, <a href="https://publications.waset.org/abstracts/search?q=glucose" title=" glucose"> glucose</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac" title=" cardiac"> cardiac</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidants" title=" antioxidants"> antioxidants</a> </p> <a href="https://publications.waset.org/abstracts/34943/the-effect-of-6-weeks-endurance-swimming-training-on-blood-glucose-and-cardiac-tissue-antioxidants-in-diabetic-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34943.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">304</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2539</span> Teaching Basic Life Support in More Than 1000 Young School Children in 5th Grade</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Booke">H. Booke</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Nordmeier"> R. Nordmeier</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sudden cardiac arrest is sometimes eye-witnessed by kids. Mostly, their (grand-)parents are affected by sudden cardiac arrest, putting these kids under enormous psychological pressure: Although they are more than desperate to help, they feel insecure and helpless and are afraid of causing harm rather than realizing their chance to help. Even years later, they may blame themselves for not having helped their beloved ones. However, the absolute majority of school children - at least in Germany - is not educated to provide first aid. Teaching young kids (5th grade) in basic life support thus may help to save lives while washing away the kids' fear from causing harm during cardio-pulmonary resuscitation. A teaching of circulatory and respiratory (patho-)physiology, followed by hands-on training of basic life support for every single child, was offered to each school in our district. The teaching was performed by anesthesiologists, and the program was called 'kids can save lives'. However, before enrollment in this program, the entire class must have had lessons in biology with a special focus on heart and circulation as well as lung and gas exchange. More than 1.000 kids were taught and trained in basic life support, giving them the knowledge and skills to provide basic life support. This may help to reduce the rate of failure to provide first aid. Therefore, educating young kids in basic life support may not only help to save lives, but it also may help to prevent any feelings of guilt because of not having helped in cases of eye-witnessed sudden cardiac arrest. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=teaching" title="teaching">teaching</a>, <a href="https://publications.waset.org/abstracts/search?q=children" title=" children"> children</a>, <a href="https://publications.waset.org/abstracts/search?q=basic%20life%20support" title=" basic life support"> basic life support</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20arrest" title=" cardiac arrest"> cardiac arrest</a>, <a href="https://publications.waset.org/abstracts/search?q=CPR" title=" CPR"> CPR</a> </p> <a href="https://publications.waset.org/abstracts/130699/teaching-basic-life-support-in-more-than-1000-young-school-children-in-5th-grade" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/130699.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">133</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2538</span> Camel Thorn Has Hepatoprotective Activity Against Carbon Tetrachloride or Acetaminophen-Induced Hepatotoxicity but Enhances the Cardiac Toxicity of Adriamycin in Rodents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Awad%20G.%20Abdellatif">Awad G. Abdellatif</a>, <a href="https://publications.waset.org/abstracts/search?q=Huda%20M.%20Gargoum"> Huda M. Gargoum</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdelkader%20A.%20Debani"> Abdelkader A. Debani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mudafara%20Bengleil"> Mudafara Bengleil</a>, <a href="https://publications.waset.org/abstracts/search?q=Salmin%20Alshalmani"> Salmin Alshalmani</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20El%20Zuki"> N. El Zuki</a>, <a href="https://publications.waset.org/abstracts/search?q=Omran%20El%20Fitouri"> Omran El Fitouri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the administration of 660 mg/kg of the ethanolic extract of the Alhgigraecorum (camel thorn) to mice, showed a significant decrease in the level of transaminases in animals treated with a combination of CTE plus carbon tetrachloride (CCl4) or acetaminophen as compared to animals receiving CCl4 or acetaminophen alone. The histopathological investigation also confirmed that camel thorn extract protects the liver against damage-induced either by carbon tetrachloride or acetaminophen. On the other hand, the cardiac toxicity produced by adriamycin was significantly increased in the presence of the ethanolic extract of camel thorn. Our study suggested that camel thorn can protect the liver against the injury produced by carbon tetrachloride or acetaminophen, with an unexpected increase in the cardiac toxicity–induced by adriamycin in rodents. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ethanolic" title="ethanolic">ethanolic</a>, <a href="https://publications.waset.org/abstracts/search?q=alhgigraecorum" title=" alhgigraecorum"> alhgigraecorum</a>, <a href="https://publications.waset.org/abstracts/search?q=tetrachloride" title=" tetrachloride"> tetrachloride</a>, <a href="https://publications.waset.org/abstracts/search?q=acetaminophen" title=" acetaminophen"> acetaminophen</a> </p> <a href="https://publications.waset.org/abstracts/4025/camel-thorn-has-hepatoprotective-activity-against-carbon-tetrachloride-or-acetaminophen-induced-hepatotoxicity-but-enhances-the-cardiac-toxicity-of-adriamycin-in-rodents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4025.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">502</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2537</span> Case Report: Peripartum Cardiomyopathy, a Rare but Fatal Condition in Pregnancy and Puerperium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sadaf%20Abbas">Sadaf Abbas</a>, <a href="https://publications.waset.org/abstracts/search?q=HimGauri%20Sabnis"> HimGauri Sabnis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Peripartum cardiomyopathy is a rare but potentially life-threatening condition that presents as heart failure during the last month of pregnancy or within five months postpartum. The incidence of postpartum cardiomyopathy ranges from 1 in 1300 to 1 in 15,000 pregnancies. Risk factors include multiparty, advanced maternal age, multiple pregnancies, pre-eclampsia, and chronic hypertension. Study: A 30-year-old Para3+0 presented to the Emergency Department of St’Marry Hospital, Isle of Wight, on the seventh day postpartum, with acute shortness of breath (SOB), chest pain, cough, and a temperature of 38 degrees. The risk factors were smoking and class II obesity (BMI of 40.62). The patient had mild pre-eclampsia in the last pregnancy and was on labetalol and aspirin during an antenatal period, which was stopped postnatally. There was also a history of pre-eclampsia and haemolysis, elevated liver enzymes, low platelets (HELLP syndrome) in previous pregnancies, which led to preterm delivery at 35 weeks in the second pregnancy, and the first baby was stillborn at 24 weeks. On assessment, there was a national early warning score (NEWS score) of 3, persistent tachycardia, and mild crepitation in the lungs. Initial investigations revealed an enlarged heart on chest X-ray, and a CT pulmonary angiogram indicated bilateral basal pulmonary congestion without pulmonary embolism, suggesting fluid overload. Laboratory results showed elevated CRP and normal troponin levels initially, which later increased, indicating myocardial involvement. Echocardiography revealed a severely dilated left ventricle with an ejection fraction (EF) of 31%, consistent with severely impaired systolic function. The cardiology team reviewed the patient and admitted to the Coronary Care Unit. As sign and symptoms were suggestive of fluid overload and congestive cardiac failure, management was done with diuretics, beta-blockers, angiotensin-converting enzyme inhibitors (ACE inhibitors), proton pump inhibitors, and supportive care. During admission, there was complications such as acute kidney injury, but then recovered well. Chest pain had resolved following the treatment. After being admitted for eight days, there was an improvement in the symptoms, and the patient was discharged home with a further plan of cardiac MRI and genetic testing due to a family history of sudden cardiac death. Regular appointment has been made with the Cardiology team to follow-up on the symptoms. Since discharge, the patient made a good recovery. A cardiac MRI was done, which showed severely impaired left ventricular function, ejection fraction (EF) of 38% with mild left ventricular dilatation, and no evidence of previous infarction. Overall appearance is of non-ischemic dilated cardiomyopathy. The main challenge at the time of admission was the non-availability of a cardiac radiology team, so the definitive diagnosis was delayed. The long-term implications include risk of recurrence, chronic heart failure, and, consequently, an effect on quality of life. Therefore, regular follow-up is critical in patient’s management. Conclusions: Peripartum cardiomyopathy is one of the cardiovascular diseases whose causes are still unknown yet and, in some cases, are uncontrolled. By raising awareness about the symptoms and management of this complication it will reduce morbidity and mortality rates and also the length of stay in the hospital. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiomyopathy" title="cardiomyopathy">cardiomyopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiomegaly" title=" cardiomegaly"> cardiomegaly</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=puerperium" title=" puerperium"> puerperium</a> </p> <a href="https://publications.waset.org/abstracts/189014/case-report-peripartum-cardiomyopathy-a-rare-but-fatal-condition-in-pregnancy-and-puerperium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189014.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">30</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2536</span> The Cardiac Diagnostic Prediction Applied to a Designed Holter</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leonardo%20Juan%20Ram%C3%ADrez%20L%C3%B3pez">Leonardo Juan Ramírez López</a>, <a href="https://publications.waset.org/abstracts/search?q=Javier%20Oswaldo%20Rodriguez%20Velasquez"> Javier Oswaldo Rodriguez Velasquez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We have designed a Holter that measures the heart´s activity for over 24 hours, implemented a prediction methodology, and generate alarms as well as indicators to patients and treating physicians. Various diagnostic advances have been developed in clinical cardiology thanks to Holter implementation; however, their interpretation has largely been conditioned to clinical analysis and measurements adjusted to diverse population characteristics, thus turning it into a subjective examination. This, however, requires vast population studies to be validated that, in turn, have not achieved the ultimate goal: mortality prediction. Given this context, our Insight Research Group developed a mathematical methodology that assesses cardiac dynamics through entropy and probability, creating a numerical and geometrical attractor which allows quantifying the normalcy of chronic and acute disease as well as the evolution between such states, and our Tigum Research Group developed a holter device with 12 channels and advanced computer software. This has been shown in different contexts with 100% sensitivity and specificity results. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=attractor" title="attractor ">attractor </a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac" title=" cardiac"> cardiac</a>, <a href="https://publications.waset.org/abstracts/search?q=entropy" title=" entropy"> entropy</a>, <a href="https://publications.waset.org/abstracts/search?q=holter" title=" holter"> holter</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical" title=" mathematical "> mathematical </a>, <a href="https://publications.waset.org/abstracts/search?q=prediction" title=" prediction"> prediction</a> </p> <a href="https://publications.waset.org/abstracts/115339/the-cardiac-diagnostic-prediction-applied-to-a-designed-holter" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/115339.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">169</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2535</span> Electrical Cardiac Remodeling in Elite Athletes: A Comparative Study between Triathletes and Cyclists</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lingxia%20Li">Lingxia Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Fr%C3%A9d%C3%A9ric%20Schnell"> Frédéric Schnell</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Lachard"> Thibault Lachard</a>, <a href="https://publications.waset.org/abstracts/search?q=Anne-Charlotte%20Dupont"> Anne-Charlotte Dupont</a>, <a href="https://publications.waset.org/abstracts/search?q=Shuzhe%20Ding"> Shuzhe Ding</a>, <a href="https://publications.waset.org/abstracts/search?q=Sol%C3%A8ne%20Le%20Douairon%20Lahaye"> Solène Le Douairon Lahaye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Repetitive participation in triathlon training results in significant myocardial changes. However, whether the cardiac remodeling in triathletes is related to the specificities of the sport (consisting of three sports) raises questions. Methods: Elite triathletes and cyclists registered on the French ministerial lists of high-level athletes were involved. The basic information and routine electrocardiogram records were obtained. Electrocardiograms were evaluated according to clinical criteria. Results: Of the 105 athletes included in the study, 42 were from the short-distance triathlon (40%), and 63 were from the road cycling (60%). The average age was 22.1±4.2 years. The P wave amplitude was significantly lower in triathletes than in cyclists (p=0.005), and no significant statistical difference was found in heart rate, RR interval, PR or PQ interval, QRS complex, QRS axe, QT interval, and QTc (p>0.05). All the measured parameters were within normal ranges. The most common electrical manifestations were early repolarization (60.95%) and incomplete right bundle branch block (43.81%); there was no statistical difference between the groups (p>0.05). Conclusions: Prolonged intensive endurance exercise training induces physiological cardiac remodeling in both triathletes and cyclists. The most common electrocardiogram manifestations were early repolarization and incomplete right bundle branch block. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20screening" title="cardiac screening">cardiac screening</a>, <a href="https://publications.waset.org/abstracts/search?q=electrocardiogram" title=" electrocardiogram"> electrocardiogram</a>, <a href="https://publications.waset.org/abstracts/search?q=triathlon" title=" triathlon"> triathlon</a>, <a href="https://publications.waset.org/abstracts/search?q=cycling" title=" cycling"> cycling</a>, <a href="https://publications.waset.org/abstracts/search?q=elite%20athletes" title=" elite athletes"> elite athletes</a> </p> <a href="https://publications.waset.org/abstracts/194909/electrical-cardiac-remodeling-in-elite-athletes-a-comparative-study-between-triathletes-and-cyclists" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194909.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">6</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2534</span> Sex Difference of the Incidence of Sudden Cardiac Arrest/Death in Athletes: A Systematic Review and Meta-analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lingxia%20Li">Lingxia Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Fr%C3%A9d%C3%A9ric%20Schnell"> Frédéric Schnell</a>, <a href="https://publications.waset.org/abstracts/search?q=Shuzhe%20Ding"> Shuzhe Ding</a>, <a href="https://publications.waset.org/abstracts/search?q=Sol%C3%A8ne%20Le%20Douairon%20Lahaye"> Solène Le Douairon Lahaye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The risk of sudden cardiac arret/death (SCA/D) in athletes is controversial. There is a lack of meta-analyses assessing the sex differences in the risk of SCA/D in competitive athletes. Purpose: The aim of the present study was to evaluate sex differences in the incidence of SCA/D in competitive athletes using meta-analyses. Methods: The systematic review was registered in the PROSPERO database (registration ID: CRD42023432022) and was conducted according to the PRISMA guidelines. PubMed, Embase, Scopus, SPORT Discus and Cochrane Library were searched up to July 2023. To avoid systematic bias in data pooling, only studies with data for both sexes were included. Results: From the 18 included studies, 2028 cases of SCA/D were observed (males 1821 (89.79%), females 207 (10.21%)). The age ranges from the adolescents (<26 years) to the elderly (>45 years). The incidence in male athletes was 1.32/100,000 AY (95% CI: [0.90, 1.93]) and in females was 0.26/100,000 AY (95% CI: [0.16, 0.43]), the incidence rate ratio (IRR) was 6.43 (95% CI: [4.22, 9.79]). The subgroup synthesis showed a higher incidence in males than in females in both age groups <25 years and ≤35 years, the IRR was 5.86 (95% CI: [4.69, 7.32]) and 5.79 (95% CI: [4.73, 7.09]), respectively. When considering the events, the IRR was 6.73 (95%CI: [3.06, 14.78]) among studies involving both SCA/D events and 7.16 (95% CI: [4.93, 10.40]) among studies including only cases of SCD. The available clinical evidence showed that cardiac events were most frequently seen in long-distance running races (26, 35.1%), marathon (16, 21.6%) and soccer (10, 13.5%). Coronary artery disease (14, 18.9%), hypertrophic cardiomyopathy (8, 10.8%), and arrhythmogenic right ventricular cardiomyopathy (7, 9.5%) are the most common causes of SCA/D in competitive athletes. Conclusion: The meta-analysis provides evidence of sex differences in the incidence of SCA/D in competitive athletes. The incidence of SCA/D in male athletes was 6 to 7 times higher than in females. Identifying the reasons for this difference may have implications for targeted the prevention of fatal evets in athletes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=incidence" title="incidence">incidence</a>, <a href="https://publications.waset.org/abstracts/search?q=sudden%20cardiac%20arrest" title=" sudden cardiac arrest"> sudden cardiac arrest</a>, <a href="https://publications.waset.org/abstracts/search?q=sudden%20cardiac%20death" title=" sudden cardiac death"> sudden cardiac death</a>, <a href="https://publications.waset.org/abstracts/search?q=sex%20difference" title=" sex difference"> sex difference</a>, <a href="https://publications.waset.org/abstracts/search?q=athletes" title=" athletes"> athletes</a> </p> <a href="https://publications.waset.org/abstracts/173995/sex-difference-of-the-incidence-of-sudden-cardiac-arrestdeath-in-athletes-a-systematic-review-and-meta-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173995.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">64</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2533</span> Bioelectronic System for Continuous Monitoring of Cardiac Activity of Benthic Invertebrates for the Assessment of a Surface Water Quality</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sergey%20Kholodkevich">Sergey Kholodkevich</a>, <a href="https://publications.waset.org/abstracts/search?q=Tatiana%20Kuznetsova"> Tatiana Kuznetsova</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The objective assessment of ecological state of water ecosystems is impossible without the use of biological methods of the environmental monitoring capable in the integrated look to reveal negative for biota changes of quality of water as habitats. Considerable interest for the development of such methods of environmental quality control represents biomarker approach. Measuring systems, by means of which register cardiac activity characteristics, received the name of bioelectronic. Bioelectronic systems are information and measuring systems in which animals (namely, benthic invertebrates) are directly included in structure of primary converters, being an integral part of electronic system of registration of these or those physiological or behavioural biomarkers. As physiological biomarkers various characteristics of cardiac activity of selected invertebrates have been used in bioelectronic system.lChanges in cardiac activity are considered as integrative measures of the physiological condition of organisms, which reflect the state of the environment of their dwelling. Greatest successes in the development of tools of biological methods and technologies of an assessment of surface water quality in real time. Essential advantage of bioindication of water quality by such tool is a possibility of an integrated assessment of biological effects of pollution on biota and also the expressness of such method and used approaches. In the report the practical experience of authors in biomonitoring and bioindication of an ecological condition of sea, brackish- and freshwater areas is discussed. Authors note that the method of non-invasive cardiac activity monitoring of selected invertebrates can be used not only for the advancement of biomonitoring, but also is useful in decision of general problems of comparative physiology of the invertebrates. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=benthic%20invertebrates" title="benthic invertebrates">benthic invertebrates</a>, <a href="https://publications.waset.org/abstracts/search?q=physiological%20state" title=" physiological state"> physiological state</a>, <a href="https://publications.waset.org/abstracts/search?q=heart%20rate%20monitoring" title=" heart rate monitoring"> heart rate monitoring</a>, <a href="https://publications.waset.org/abstracts/search?q=water%20quality%20assessment" title=" water quality assessment"> water quality assessment</a> </p> <a href="https://publications.waset.org/abstracts/15523/bioelectronic-system-for-continuous-monitoring-of-cardiac-activity-of-benthic-invertebrates-for-the-assessment-of-a-surface-water-quality" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15523.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">717</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2532</span> Effect of SCN5A Gene Mutation in Endocardial Cell</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Helan%20Satish">Helan Satish</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Ramasubba%20Reddy"> M. Ramasubba Reddy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The simulation of an endocardial cell for gene mutation in the cardiac sodium ion channel NaV1.5, encoded by SCN5A gene, is discussed. The characterization of Brugada Syndrome by loss of function effect on SCN5A mutation due to L812Q mutant present in the DII-S4 transmembrane region of the NaV1.5 channel protein and its effect in an endocardial cell is studied. Ten Tusscher model of human ventricular action potential is modified to incorporate the changes contributed by L812Q mutant in the endocardial cells. Results show that BrS-associated SCN5A mutation causes reduction in the inward sodium current by modifications in the channel gating dynamics such as delayed activation, enhanced inactivation, and slowed recovery from inactivation in the endocardial cell. A decrease in the inward sodium current was also observed, which affects depolarization phase (Phase 0) that leads to reduction in the spike amplitude of the cardiac action potential. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SCN5A%20gene%20mutation" title="SCN5A gene mutation">SCN5A gene mutation</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20channel" title=" sodium channel"> sodium channel</a>, <a href="https://publications.waset.org/abstracts/search?q=Brugada%20syndrome" title=" Brugada syndrome"> Brugada syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20arrhythmia" title=" cardiac arrhythmia"> cardiac arrhythmia</a>, <a href="https://publications.waset.org/abstracts/search?q=action%20potential" title=" action potential"> action potential</a> </p> <a href="https://publications.waset.org/abstracts/126001/effect-of-scn5a-gene-mutation-in-endocardial-cell" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/126001.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">126</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2531</span> Relationship between Left Ventricle Position and Hemodynamic Parameters during Cardiopulmonary Resuscitation in a Pig Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hyun%20Chang%20Kim">Hyun Chang Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Yong%20Hun%20Jung"> Yong Hun Jung</a>, <a href="https://publications.waset.org/abstracts/search?q=Kyung%20Woon%20Jeung"> Kyung Woon Jeung</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: From the viewpoint of cardiac pump theory, the area of the left ventricle (LV) subjected to compression increases as the LV lies closer to the sternum, possibly resulting in higher blood flow in patients with LV closer to the sternum. However, no study has evaluated LV position during cardiac arrest or its relationship with hemodynamic parameters during cardiopulmonary resuscitation (CPR). The objectives of this study were to determine whether the position of the LV relative to the anterior-posterior axis representing the direction of chest compression shifts during cardiac arrest and to examine the relationship between LV position and hemodynamic parameters during CPR. Methods: Subcostal view echocardiograms were obtained from 15 pigs with the transducer parallel to the long axis of the sternum before inducing ventricular fibrillation (VF) and during cardiac arrest. Computed tomography was performed in three pigs to objectively observe LV position during cardiac arrest. LV position parameters including the shortest distance between the anterior-posterior axis and the mid-point of the LV chamber (DAP-MidLV), the shortest distance between the anterior-posterior axis and the LV apex (DAP-Apex), and the area fraction of the LV located on the right side of the anterior-posterior axis (LVARight/LVATotal) were measured. Results: DAP-MidLV, DAP-Apex, and LVARight/LVATotal decreased progressively during untreated VF and basic life support (BLS), and then increased during advanced cardiovascular life support (ACLS). A repeated measures analysis of variance revealed significant time effects for these parameters. During BLS, the end-tidal carbon dioxide and systolic right atrial pressure were significantly correlated with the LV position parameters. During ACLS, systolic arterial pressure and systolic right atrial pressure were significantly correlated with DAP-MidLV and DAP-Apex. Conclusions: LV position changed significantly during cardiac arrest compared to the pre-arrest baseline. LV position during CPR had significant correlations with hemodynamic parameters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=heart%20arrest" title="heart arrest">heart arrest</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiopulmonary%20resuscitation" title=" cardiopulmonary resuscitation"> cardiopulmonary resuscitation</a>, <a href="https://publications.waset.org/abstracts/search?q=heart%20ventricle" title=" heart ventricle"> heart ventricle</a>, <a href="https://publications.waset.org/abstracts/search?q=hemodynamics" title=" hemodynamics"> hemodynamics</a> </p> <a href="https://publications.waset.org/abstracts/74177/relationship-between-left-ventricle-position-and-hemodynamic-parameters-during-cardiopulmonary-resuscitation-in-a-pig-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74177.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">189</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2530</span> Stress Hyperglycemia: A Predictor of Major Adverse Cardiac Events in Non-Diabetic Patients With Acute Heart Failure</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fahad%20Raj%20Khan">Fahad Raj Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Suleman%20Khan"> Suleman Khan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There is a lack of consensus about the predictive value of raised blood glucose levels in terms of major adverse cardiac events (MACEs) in non-diabetic patients admitted for acute decompensated heart failure. The purpose of this research was to examine the long-term prognosis of acute decompensated heart failure (ADHF) in non-diabetic persons who had increased blood glucose levels, i.e., stress hyperglycemia, at the time of their ADHF hospitalization. The research involved 650 non-diabetic patients. Based on their admission stress hyperglycemia, they were divided into two groups.ie with and without (SHGL). The two groups' one-year outcomes for major adverse cardiac events (MACEs) were compared, and key predictors of MACEs were discovered. For statistical analysis, the two-tailed Mann-Whitney U test, Fisher's exact test, and binary logistic regression analysis were utilized. SHGL was found in 353 (54.3%) individuals. It was more frequent in men than in women. About 27% of patients with SHGL had previously been admitted for ADHF. Almost 62% were hypertensive, whereas 14 % had CKD. MACEs were significantly predicted by SHGL, HTN, prior hospitalization for ADHF, CKD, and cardiogenic shock upon admission. SHGL at the time of ADHF admission, independent of DM status, may be a predictive indication of MACEs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress%20hyperglycemia" title="stress hyperglycemia">stress hyperglycemia</a>, <a href="https://publications.waset.org/abstracts/search?q=acute%20heart%20failure" title=" acute heart failure"> acute heart failure</a>, <a href="https://publications.waset.org/abstracts/search?q=major%20adverse%20cardiac%20events" title=" major adverse cardiac events"> major adverse cardiac events</a>, <a href="https://publications.waset.org/abstracts/search?q=MACEs" title=" MACEs"> MACEs</a> </p> <a href="https://publications.waset.org/abstracts/152520/stress-hyperglycemia-a-predictor-of-major-adverse-cardiac-events-in-non-diabetic-patients-with-acute-heart-failure" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152520.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2529</span> Fatty Acid Metabolism in Hypertension</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yin%20Hua%20Zhang">Yin Hua Zhang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cardiac metabolism is essential in myocardial contraction. In addition to glucose, fatty acids (FA) are essential in producing energy in the myocardium since FA-dependent beta-oxidation accounts for > 70-90% of cellular ATP under resting conditions. However, metabolism shifts from FAs to glucose utilization during disease progression (e.g. hypertrophy and ischemic myocardium), where glucose oxidation and glycolysis become the predominant sources of cellular ATP. At advanced failing stage, both glycolysis and beta-oxidation are dysregulated, result in insufficient supply of intracellular ATP and weakened myocardial contractility. Undeniably, our understandings of myocyte function in healthy and diseased hearts are based on glucose (10 mM)-dependent metabolism because glucose is the “sole” metabolic substrate in most of the physiological experiments. In view of the importance of FAs in cardiovascular health and diseases, we aimed to elucidate the impacts of FA supplementation on myocyte contractility and evaluate cellular mechanisms those mediate the functions in normal heart and with pathological stress. In particular, we have investigated cardiac excitation-contraction (E-C) coupling in the presence and absence of FAs in normal and hypertensive rat left ventricular (LV) myocytes. Our results reveal that FAs increase mitochondrial activity, intracellular [Ca²+]i, and LV myocyte contraction in healthy LV myocytes, whereas FA-dependent cardiac inotropyis attenuated in hypertension. FA-dependent myofilament Ca²+ desensitization could be fundamental in regulating [Ca²+]i. Collectively, FAs supplementation resets cardiac E-C coupling scheme in healthy and diseased hearts. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hypertension" title="hypertension">hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=fatty%20acid" title=" fatty acid"> fatty acid</a>, <a href="https://publications.waset.org/abstracts/search?q=heart" title=" heart"> heart</a>, <a href="https://publications.waset.org/abstracts/search?q=calcium" title=" calcium"> calcium</a> </p> <a href="https://publications.waset.org/abstracts/147617/fatty-acid-metabolism-in-hypertension" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147617.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">109</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2528</span> Risk Factors for Post-Induction Hypotension Among Elderly Patients Undergoing Elective Non-Cardiac Surgery Under General Anesthesia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Karuna%20Sutthibenjakul">Karuna Sutthibenjakul</a>, <a href="https://publications.waset.org/abstracts/search?q=Sunisa%20Chatmongkolchart"> Sunisa Chatmongkolchart</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Postinduction hypotension is common and occurs more often in elderly patients. We aimed to determine risk factors for hypotension after induction among elderly patients (aged 65 years and older) who underwent elective non-cardiac surgery under general anesthesia. Methods: This cohort study analyzed from 580 data between December 2017 and July 2018 at a tertiary university hospital in south of Thailand. Hypotension is defined as more than 30% decrease mean arterial pressure from baseline after induction within 20 minutes or the use of vasopressive agent to treat low blood pressure. Intraoperative parameters were blood pressure and heart rate at T0, TEI, T5, T10, T15 and T20 (immediately after arrival at operating room, time after intubation, 5, 10, 15 and 20 minutes after intubation) respectively. Results: The median age was 72.5 (68, 78) years. A prevalence of post-induction hypotension was 64.8%. The highest prevalence (39.7%) was at 15 minutes after intubation. The association of post-induction hypotension is rising with diuretic drug as preoperative medication (P-value=0.016), hematocrit level (P-value=0.031) and the degree of hypertension immediately after arrival at operating room (P-value<0.001). Increasing fentanyl dosage during induction was associated with hypotension at intubation time (P-value<0.01) and 5 minutes after intubation (P-value<0.001). There was no statistically significant difference in the increasing propofol dosage. Conclusion: The degree of hypertension immediately after arrival at operating room and increasing fentanyl dosage were a significant risk factors for postinduction hypotension in elderly patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title="risk factors">risk factors</a>, <a href="https://publications.waset.org/abstracts/search?q=post-induction" title=" post-induction"> post-induction</a>, <a href="https://publications.waset.org/abstracts/search?q=hypotension" title=" hypotension"> hypotension</a>, <a href="https://publications.waset.org/abstracts/search?q=elderly" title=" elderly"> elderly</a> </p> <a href="https://publications.waset.org/abstracts/102038/risk-factors-for-post-induction-hypotension-among-elderly-patients-undergoing-elective-non-cardiac-surgery-under-general-anesthesia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/102038.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">131</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2527</span> Outcome of Anastomosis of Mechanically Prepared vs Mechanically Unprepared Bowel in Laparoscopic Anterior Resection in Surgical Units of Teaching Hospital Karapitiya ,Sri Lanka</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20P.%20v.%20R.%20de%20Silva">K. P. v. R. de Silva</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20W.%20Senevirathna"> R. W. Senevirathna</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20M.%20A.%20J.%20Kumara"> M. M. A. J. Kumara</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20P.%20M.%20Kumarasinghe"> J. P. M. Kumarasinghe</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20L.%20Gunawardana"> R. L. Gunawardana</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20M.%20Uluwitiya"> S. M. Uluwitiya</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20C.%20P.%20Jayawickrama"> G. C. P. Jayawickrama</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20K.%20T.%20I.%20Madushani"> W. K. T. I. Madushani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The limited literature supporting the utilization of mechanical bowel preparation (MBP) for patients undergoing laparoscopic anterior resection (LAR) remains a notable issue. This study was conducted to examine the clinical consequences of anastomosis in colorectal surgery with MBP compared to cases where MBP was not utilized (no-MBP) in the context of LAR. Methods: This was a retrospective comparative study conducted in the professorial surgical wards of the teaching hospital karapitiya (THK). Colorectal cancer patients(n=306) participated in the study, including 151 MBP patients and 155 no-MBP patients, where the postoperative complications and mortality rates were compared. Results: The anastomotic leakage rate was 2.6%(n=4) in the no-MBP group and 6.0%(n=9) in the MBP group (p=0.143). The postoperative paralytic ileus rate was 18.5%(n=28) and 5.8%(n=9) in the MBP group and no-MBP group, respectively, displaying a statistically significant difference (p=0.001). Wound infection, pneumonia, urinary tract infection, and cardiac complication rates also were higher in the MBP group. The overall mortality rate was 1.3%(n=3) in the no-MBP group and 2.0%(n=2) in the MBP group. Conclusions: The evidence concludes that MBP increases post-operative complications. Therefore, prophylactic MBP in LAR has not been proven to benefit patients. However, further research is necessary to understand the comparative effects of MBP versus no preparation comprehensively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MBP" title="MBP">MBP</a>, <a href="https://publications.waset.org/abstracts/search?q=anastomosis" title=" anastomosis"> anastomosis</a>, <a href="https://publications.waset.org/abstracts/search?q=LAR" title=" LAR"> LAR</a>, <a href="https://publications.waset.org/abstracts/search?q=paralytic%20ileus" title=" paralytic ileus"> paralytic ileus</a> </p> <a href="https://publications.waset.org/abstracts/171864/outcome-of-anastomosis-of-mechanically-prepared-vs-mechanically-unprepared-bowel-in-laparoscopic-anterior-resection-in-surgical-units-of-teaching-hospital-karapitiya-sri-lanka" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171864.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">92</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2526</span> A Second Chance to Live and Move: Lumbosacral Spinal Cord Ischemia-Infarction after Cardiac Arrest and the Artery of Adamkiewicz</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anna%20Demian">Anna Demian</a>, <a href="https://publications.waset.org/abstracts/search?q=Levi%20Howard"> Levi Howard</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Ng"> L. Ng</a>, <a href="https://publications.waset.org/abstracts/search?q=Leslie%20Simon"> Leslie Simon</a>, <a href="https://publications.waset.org/abstracts/search?q=Mark%20Dragon"> Mark Dragon</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Desai"> A. Desai</a>, <a href="https://publications.waset.org/abstracts/search?q=Timothy%20Devlantes"> Timothy Devlantes</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20David%20Freeman"> W. David Freeman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Out-of-hospital cardiac arrest (OHCA) can carry a high mortality. For survivors, the most common complication is hypoxic-ischemic brain injury (HIBI). Rarely, lumbosacral spinal cord and/or other spinal cord artery ischemia can occur due to anatomic variation and variable mean arterial pressure after the return of spontaneous circulation. We present a case of an OHCA survivor who later woke up with bilateral leg weakness with preserved sensation (ASIA grade B, L2 level). Methods: We describe a clinical, radiographic, and laboratory presentation, as well as a National Library of Medicine (NLM) search engine methodology, characterizing incidence/prevalence of this entity is discussed. A 70-year-old male, a longtime smoker, and alcohol user, suddenly collapsed at a bar surrounded by friends. He had complained of chest pain before collapsing. 911 was called. EMS arrived, and the patient was in pulseless electrical activity (PEA), cardiopulmonary resuscitation (CPR) was initiated, and the patient was intubated, and a LUCAS device was applied for continuous, high-quality CPR in the field by EMS. In the ED, central lines were placed, and thrombolysis was administered for a suspected Pulmonary Embolism (PE). It was a prolonged code that lasted 90 minutes. The code continued with the eventual return of spontaneous circulation. The patient was placed on an epinephrine and norepinephrine drip to maintain blood pressure. ECHO was performed and showed a “D-shaped” ventricle worrisome for PE as well as an ejection fraction around 30%. A CT with PE protocol was performed and confirmed bilateral PE. Results: The patient woke up 24 hours later, following commands, and was extubated. He was found paraplegic below L2 with preserved sensation, with hypotonia and areflexia consistent with “spinal shock” or anterior spinal cord syndrome. MRI thoracic and lumbar spine showed a conus medullaris level spinal cord infarction. The patient was given IV steroids upon initial discovery of cord infarct. NLM search using “cardiac arrest” and “spinal cord infarction” revealed 57 results, with only 8 review articles. Risk factors include age, atherosclerotic disease, and intraaortic balloon pump placement. AoA (Artery of Adamkiewicz) anatomic variation along with existing atherosclerotic factors and low perfusion were also known risk factors. Conclusion: Acute paraplegia from anterior spinal cord infarction of the AoA territory after cardiac arrest is rare. Larger prospective, multicenter trials are needed to examine potential interventions of hypothermia, lumbar drains, which are sometimes used in aortic surgery to reduce ischemia and/or other neuroprotectants. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20arrest" title="cardiac arrest">cardiac arrest</a>, <a href="https://publications.waset.org/abstracts/search?q=spinal%20cord%20infarction" title=" spinal cord infarction"> spinal cord infarction</a>, <a href="https://publications.waset.org/abstracts/search?q=artery%20of%20Adamkiewicz" title=" artery of Adamkiewicz"> artery of Adamkiewicz</a>, <a href="https://publications.waset.org/abstracts/search?q=paraplegia" title=" paraplegia"> paraplegia</a> </p> <a href="https://publications.waset.org/abstracts/141427/a-second-chance-to-live-and-move-lumbosacral-spinal-cord-ischemia-infarction-after-cardiac-arrest-and-the-artery-of-adamkiewicz" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141427.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">189</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2525</span> Temperature-Dependent Post-Mortem Changes in Human Cardiac Troponin-T (cTnT): An Approach in Determining Postmortem Interval</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sachil%20Kumar">Sachil Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Anoop%20Kumar%20Verma"> Anoop Kumar Verma</a>, <a href="https://publications.waset.org/abstracts/search?q=Wahid%20Ali"> Wahid Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Uma%20Shankar%20Singh"> Uma Shankar Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Globally approximately 55.3 million people die each year. In the India there were 95 lakh annual deaths in 2013. The number of deaths resulted from homicides, suicides and unintentional injuries in the same period was about 5.7 lakh. The ever-increasing crime rate necessitated the development of methods for determining time since death. An erroneous time of death window can lead investigators down the wrong path or possibly focus a case on an innocent suspect. In this regard a research was carried out by analyzing the temperature dependent degradation of a Cardiac Troponin-T protein (cTnT) in the myocardium postmortem as a marker for time since death. Cardiac tissue samples were collected from (n=6) medico-legal autopsies, (in the Department of Forensic Medicine and Toxicology, King George’s Medical University, Lucknow India) after informed consent from the relatives and studied post-mortem degradation by incubation of the cardiac tissue at room temperature (20±2 OC), 12 0C, 25 0C and 37 0C for different time periods ((~5, 26, 50, 84, 132, 157, 180, 205, and 230 hours). The cases included were the subjects of road traffic accidents (RTA) without any prior history of disease who died in the hospital and their exact time of death was known. The analysis involved extraction of the protein, separation by denaturing gel electrophoresis (SDS-PAGE) and visualization by Western blot using cTnT specific monoclonal antibodies. The area of the bands within a lane was quantified by scanning and digitizing the image using Gel Doc. The data shows a distinct temporal profile corresponding to the degradation of cTnT by proteases found in cardiac muscle. The disappearance of intact cTnT and the appearance of lower molecular weight bands are easily observed. Western blot data clearly showed the intact protein at 42 kDa, two major (27 kDa, 10kDa) fragments, two additional minor fragments (32 kDa) and formation of low molecular weight fragments as time increases. At 12 0C the intensity of band (intact cTnT) decreased steadily as compared to RT, 25 0C and 37 0C. Overall, both PMI and temperature had a statistically significant effect where the greatest amount of protein breakdown was observed within the first 38 h and at the highest temperature, 37 0C. The combination of high temperature (37 0C) and long Postmortem interval (105.15 hrs) had the most drastic effect on the breakdown of cTnT. If the percent intact cTnT is calculated from the total area integrated within a Western blot lane, then the percent intact cTnT shows a pseudo-first order relationship when plotted against the log of the time postmortem. These plots show a good coefficient of correlation of r = 0.95 (p=0.003) for the regression of the human heart at different temperature conditions. The data presented demonstrates that this technique can provide an extended time range during which Postmortem interval can be more accurately estimated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=degradation" title="degradation">degradation</a>, <a href="https://publications.waset.org/abstracts/search?q=postmortem%20interval" title=" postmortem interval"> postmortem interval</a>, <a href="https://publications.waset.org/abstracts/search?q=proteolysis" title=" proteolysis"> proteolysis</a>, <a href="https://publications.waset.org/abstracts/search?q=temperature" title=" temperature"> temperature</a>, <a href="https://publications.waset.org/abstracts/search?q=troponin" title=" troponin"> troponin</a> </p> <a href="https://publications.waset.org/abstracts/30306/temperature-dependent-post-mortem-changes-in-human-cardiac-troponin-t-ctnt-an-approach-in-determining-postmortem-interval" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30306.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2524</span> Characteristics of Children Heart Rhythm Regulation with Acute Respiratory Diseases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=D.%20F.%20Zeynalov">D. F. Zeynalov</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20V.%20Kartseva"> T. V. Kartseva</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20V.%20Sorokin"> O. V. Sorokin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Currently, approaches to assess cardiointervalography are based on the calculation of data variance intervals RR. However, they do not allow the evaluation of features related to a period of the cardiac cycle, so how electromechanical phenomena during cardiac subphase are characterized by differently directed changes. Therefore, we have proposed a method of subphase analysis of the cardiac cycle, developed in the department of hominal physiology Novosibirsk State Medical University to identify the features of the dispersion subphase of the cardiac cycle. In the present paper we have examined the 5-minute intervals cardiointervalography (CIG) to isolate RR-, QT-, ST-ranges in healthy children and children with acute respiratory diseases (ARD) in comparison. It is known that primary school-aged children suffer at ARD 5-7 times per year. Consequently, it is one of the most relevant problems in pediatrics. It is known that the spectral indices and indices of temporal analysis of heart rate variability are highly sensitive to the degree of intoxication during immunological process. We believe that the use of subphase analysis of heart rate will allow more thoroughly evaluate responsiveness of the child organism during the course of ARD. The study involved 60 primary school-aged children (30 boys and 30 girls). In order to assess heart rhythm regulation, the record CIG was used on the "VNS-Micro" device of Neurosoft Company (Ivanovo) for 5 minutes in the supine position and 5 minutes during active orthostatic test. Subphase analysis of variance QT-interval and ST-segment was performed on the "KardioBOS" software Biokvant Company (Novosibirsk). In assessing the CIG in the supine position and in during orthostasis of children with acute respiratory diseases only RR-intervals are observed typical trend of general biological reactions through pressosensitive compensation mechanisms to lower blood pressure, but compared with healthy children the severity of the changes is different, of sick children are more pronounced indicators of heart rate regulation. But analysis CIG RR-intervals and analysis subphase ST-segment have yielded conflicting trends, which may be explained by the different nature of the intra- and extracardiac influences on regulatory mechanisms that implement the various phases of the cardiac cycle. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acute%20respiratory%20diseases" title="acute respiratory diseases">acute respiratory diseases</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiointervalography" title=" cardiointervalography"> cardiointervalography</a>, <a href="https://publications.waset.org/abstracts/search?q=subphase%20analysis" title=" subphase analysis"> subphase analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20cycle" title=" cardiac cycle"> cardiac cycle</a> </p> <a href="https://publications.waset.org/abstracts/43025/characteristics-of-children-heart-rhythm-regulation-with-acute-respiratory-diseases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43025.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">275</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2523</span> Bioclimatic Design, Evaluation of Energy Behavior and Energy-Saving Interventions at the Theagenio Cancer Hospital</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Emmanouel%20Koumoulas">Emmanouel Koumoulas</a>, <a href="https://publications.waset.org/abstracts/search?q=Aikaterini%20Rokkou"> Aikaterini Rokkou</a>, <a href="https://publications.waset.org/abstracts/search?q=Marios%20Moschakis"> Marios Moschakis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Theagenio" in Thessaloniki exists and works for three centuries now as a hospital. Since 1975, it has been operating as an Integrated Special Cancer Hospital and since 1985 it has been integrated into the National Health System. "Theagenio" Cancer Hospital is located at the central web of Thessaloniki residential complex and consists of two buildings, the "Symeonidio Research Center", which was completed in 1962 and the Nursing Ward, a project that was later completed in 1975. This paper examines the design of the Hospital Unit according to the requirements of the energy design of buildings. Initially, the energy characteristics of the Hospital are recorded, followed by a detailed presentation of the electromechanical installations. After the existing situation has been captured and with the help of the software TEE-KENAK, different scenarios for the energy upgrading of the buildings have been studied. Proposals for upgrading concern both the shell, e.g. installation of external thermal insulation, replacement of frames, addition of shading systems, etc. as well as electromechanical installations, e.g. use of ceiling fans, improvements in heating and cooling systems, interventions in lighting, etc. The simulation calculates the future energy status of the buildings and presents the economic benefits of the proposed interventions with reference to the environmental profits that arise. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=energy%20consumption%20in%20hospitals" title="energy consumption in hospitals">energy consumption in hospitals</a>, <a href="https://publications.waset.org/abstracts/search?q=energy%20saving%20interventions" title=" energy saving interventions"> energy saving interventions</a>, <a href="https://publications.waset.org/abstracts/search?q=energy%20upgrading" title=" energy upgrading"> energy upgrading</a>, <a href="https://publications.waset.org/abstracts/search?q=hospital%20facilities" title=" hospital facilities"> hospital facilities</a> </p> <a href="https://publications.waset.org/abstracts/91912/bioclimatic-design-evaluation-of-energy-behavior-and-energy-saving-interventions-at-the-theagenio-cancer-hospital" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91912.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">152</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2522</span> The Impact of Hospital Strikes on Patient Care: Evidence from 135 Strikes in the Portuguese National Health System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eduardo%20Costa">Eduardo Costa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hospital strikes in the Portuguese National Health Service (NHS) are becoming increasingly frequent, raising concerns in what respects patient safety. In fact, data shows that mortality rates for patients admitted during strikes are up to 30% higher than for patients admitted in other days. This paper analyses the effects of hospital strikes on patients’ outcomes. Specifically, it analyzes the impact of different strikes (physicians, nurses and other health professionals), on in-hospital mortality rates, readmission rates and length of stay. The paper uses patient-level data containing all NHS hospital admissions in mainland Portugal from 2012 to 2017, together with a comprehensive strike dataset comprising over 250 strike days (19 physicians-strike days, 150 nurses-strike days and 50 other health professionals-strike days) from 135 different strikes. The paper uses a linear probability model and controls for hospital and regional characteristics, time trends, and changes in patients’ composition and diagnoses. Preliminary results suggest a 6-7% increase in in-hospital mortality rates for patients exposed to physicians’ strikes. The effect is smaller for patients exposed to nurses’ strikes (2-5%). Patients exposed to nurses strikes during their stay have, on average, higher 30-days urgent readmission rates (4%). Length of stay also seems to increase for patients exposed to any strike. Results – conditional on further testing, namely on non-linear models - suggest that hospital operations and service levels are partially disrupted during strikes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=health%20sector%20strikes" title="health sector strikes">health sector strikes</a>, <a href="https://publications.waset.org/abstracts/search?q=in-hospital%20mortality%20rate" title=" in-hospital mortality rate"> in-hospital mortality rate</a>, <a href="https://publications.waset.org/abstracts/search?q=length%20of%20stay" title=" length of stay"> length of stay</a>, <a href="https://publications.waset.org/abstracts/search?q=readmission%20rate" title=" readmission rate"> readmission rate</a> </p> <a href="https://publications.waset.org/abstracts/107074/the-impact-of-hospital-strikes-on-patient-care-evidence-from-135-strikes-in-the-portuguese-national-health-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/107074.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">135</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2521</span> The Admitting Hemogram as a Predictor for Severity and in-Hospital Mortality in Acute Pancreatitis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Florge%20Francis%20A.%20Sy">Florge Francis A. Sy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Acute pancreatitis (AP) is an inflammatory condition of the pancreas with local and systemic complications. Severe acute pancreatitis (SAP) has a higher mortality rate. Laboratory parameters like the neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), and mean platelet volume (MPV) have been associated with SAP but with conflicting results. This study aims to determine the predictive value of these parameters on the severity and in-hospital mortality of AP. This retrospective, cross-sectional study was done in a private hospital in Cebu City, Philippines. One-hundred five patients were classified according to severity based on the modified Marshall scoring. The admitting hemogram, including the NLR, RDW, and MPV, was obtained from the complete blood count (CBC). Cut-off values for severity and in-hospital mortality were derived from the ROC. Association between NLR, RDW, and MPV with SAP and mortality were determined with a p-value of < 0.05 considered significant. The mean age for AP was 47.6 years, with 50.5% being male. Most had an unknown cause (49.5%), followed by a biliary cause (37.1%). Of the 105 patients, 23 patients had SAP, and 4 died. Older age, longer in-hospital duration, congestive heart failure, elevated creatinine, urea nitrogen, and white blood cell count were seen in SAP. The NLR was associated with in-hospital mortality using a cut-off of > 10.6 (OR 1.133, 95% CI, p-value 0.003) with 100% sensitivity, 70.3% specificity, 11.76% PPV and 100% NPV (AUC 0.855). The NLR was not associated with SAP. The RDW and MPV were not associated with SAP and mortality. The admitting NLR is, therefore, an easily accessible parameter that can predict in-hospital mortality in acute pancreatitis. Although the present study did not show an association of NLR with SAP nor RDW and MPV with both SAP and mortality, further studies are suggested to establish their clinical value. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acute%20pancreatitis" title="acute pancreatitis">acute pancreatitis</a>, <a href="https://publications.waset.org/abstracts/search?q=mean%20platelet%20volume" title=" mean platelet volume"> mean platelet volume</a>, <a href="https://publications.waset.org/abstracts/search?q=neutrophil-lymphocyte%20ratio" title=" neutrophil-lymphocyte ratio"> neutrophil-lymphocyte ratio</a>, <a href="https://publications.waset.org/abstracts/search?q=red%20cell%20distribution%20width" title=" red cell distribution width"> red cell distribution width</a> </p> <a href="https://publications.waset.org/abstracts/133291/the-admitting-hemogram-as-a-predictor-for-severity-and-in-hospital-mortality-in-acute-pancreatitis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133291.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">123</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2520</span> Nurse Schedule Problem in Mubarak Al Kabeer Hospital</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Khaled%20Al-Mansour">Khaled Al-Mansour</a>, <a href="https://publications.waset.org/abstracts/search?q=Nawaf%20Esmael"> Nawaf Esmael</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdulaziz%20Al-Zaid"> Abdulaziz Al-Zaid</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Al%20Ateeqi"> Mohammed Al Ateeqi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20Al-Yousfi"> Ali Al-Yousfi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sayed%20Al-Zalzalah"> Sayed Al-Zalzalah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this project we will create the new schedule of nurse according to the preference of them. We did our project in Mubarak Al Kabeer Hospital (in Kuwait). The project aims to optimize the schedule of nurses in Mubarak Al Kabeer Hospital. The schedule of the nurses was studied and understood well to do any modification for their schedule to make the nurses feel as much comfort as they are. First constraints were found to know what things we can change and what things we can’t, the hard constraints are the hospital and ministry policies where we can’t change anything about, and the soft constraints are things that make nurses more comfortable. Data were collected and nurses were interviewed to know what is more better for them. All these constraints and date have been formulated to mathematical equations. This report will first contain an introduction to the topic which includes details of the problem definition. It will also contain information regarding the optimization of a nurse schedule and its contents and importance; furthermore, the report will contain information about the data needed to solve the problem and how it was collected. The problem requires formulation and that is also to be shown. The methodology will be explained which will state what has already been done. We used the lingo software to find the best schedule for the nurse. The schedule has been made according to what the nurses prefer, and also took consideration of the hospital policy when we make the schedule. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nurse%20schedule%20problem" title="nurse schedule problem">nurse schedule problem</a>, <a href="https://publications.waset.org/abstracts/search?q=Kuwait" title=" Kuwait"> Kuwait</a>, <a href="https://publications.waset.org/abstracts/search?q=hospital%20policy" title=" hospital policy"> hospital policy</a>, <a href="https://publications.waset.org/abstracts/search?q=optimization%20of%20schedules" title=" optimization of schedules"> optimization of schedules</a> </p> <a href="https://publications.waset.org/abstracts/9565/nurse-schedule-problem-in-mubarak-al-kabeer-hospital" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9565.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span 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