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expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }, /** * get the master domain based on business rules */ getMasterDomain : function () { // default the master domain var masterDomain = 'thermofisher.com'; // check for alternate domain portion of URL var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }, /** * Check if init has been initiated once * @type {Boolean} */ initted: false, /** * @return {Array} method returns an array of a given object's key properties */ init: function () { this.page.country = this.getCookie("CK_ISO_CODE") || 'us'; this.page.language = this.getCookie('CK_LANG_CODE') || 'en'; this.page.siteName = 'thermo'; //hard coded this.initMerchandisingData(); this.initUserData(); this.displayDigitalData(); this.formSubmitEvent(); }, //specific function to set type of the page // need specific function to keep page type separate from other page attributes setPageType: function (type) { this.setPageAttribute('type', type); 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µL sample of plasma, serum, cell culture supernatants, or other bodily ﬂuids. 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class="cmp-sectiontitle__text" data-anchor-nav-title="ProcartaPlex assay formats">ProcartaPlex assay formats</h2> </div> </div> <div class="cmp-p-container m--match-height"> <div id="container-d0d5b015c1" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--phone--12 "> <div class="cmp-p-container p-l1 aem-GridColumn--default--none aem-GridColumn--phone--none aem-GridColumn--phone--12 aem-GridColumn aem-GridColumn--offset--phone--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"> <div id="container-84c34de085" class="cmp-container"> <div class="aem-Grid aem-Grid--default--4 aem-Grid--phone--12 "> <div class="cmp-p-textimage m--featured-product aem-GridColumn--phone--none aem-GridColumn--phone--12 aem-GridColumn aem-GridColumn--offset--phone--0 aem-GridColumn--default--4"><div class="cmp-textimage cta-container" id="textimage-197684374" data-cmp-hook-cta="ctapanel"> <div class="cmp-textoverlay"> <div class="cmp-textoverlay__textwrapper"> <h2 class="cmp-textoverlay__title">Preconfigured Panels</h2> <p>Select from predefined, biologically relevant, disease-defined panels, helping ensure optimal performance and reproducibility through extensive testing for combinability, cross-reactivity, and interference.</p> </div> <div class="cmp-ctalist"> <div class="cmp-p-ctaitem"><div class="cmp-ctaitem" id="ctaitem-58299f5f24"> <a class="cmp-ctaitem__anchor" href="/search/browse/category/us/en/90332032?filter=dimProductType_dim_ss%3AMultiplex%20Panel"> <span class="cmp-ctaitem__icon icon-24-arrow-right-mono"></span> <span class="cmp-ctaitem__text">Search available preconfigured panels</span> </a> </div> </div> </div> </div> <div data-cmp-is="image" data-cmp-src="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Preconfigured-panels-badge-v3.png" data-asset="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Preconfigured-panels-badge-v3.png" 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With over 90% of our analytes being combinable, our ProcartaPlex system offers excellent flexibility on the market.</p> </div> <div class="cmp-ctalist"> <div class="cmp-p-ctaitem"><div class="cmp-ctaitem" id="ctaitem-144255a11a"> <a class="cmp-ctaitem__anchor" href="/order/luminex/"> <span class="cmp-ctaitem__icon icon-24-arrow-right-mono"></span> <span class="cmp-ctaitem__text">Build your own panel</span> </a> </div> </div> </div> </div> <div data-cmp-is="image" data-cmp-src="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Mix-and-Match-Badge-v2.png" data-asset="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Mix-and-Match-Badge-v2.png" data-title="Mix and batch icon" id="textimage-133048696" class="cmp-image " itemscope itemtype="http://schema.org/ImageObject"> <a class="cmp-image__link" href="/order/luminex/" data-cmp-hook-image="link"> <noscript data-cmp-hook-image="noscript"> <img src="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Mix-and-Match-Badge-v2.png" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Mix and batch icon" title="Mix and batch icon"/> </noscript> </a> <meta itemprop="caption" content="Mix and batch icon"/> </div>  </div> </div> </div> </div> </div> <div class="cmp-p-container p-l1 aem-GridColumn--default--none aem-GridColumn--phone--none aem-GridColumn--phone--12 aem-GridColumn aem-GridColumn--offset--phone--0 aem-GridColumn--offset--default--0 aem-GridColumn--default--4"> <div id="container-c2f5db880d" class="cmp-container"> <div class="aem-Grid aem-Grid--default--4 aem-Grid--phone--12 "> <div class="cmp-p-textimage m--featured-product aem-GridColumn--phone--none aem-GridColumn--phone--12 aem-GridColumn aem-GridColumn--offset--phone--0 aem-GridColumn--default--4"><div class="cmp-textimage cta-container" id="textimage-509685977" data-cmp-hook-cta="ctapanel"> <div class="cmp-textoverlay"> <div class="cmp-textoverlay__textwrapper"> <h2 class="cmp-textoverlay__title">Simplex Kits</h2> <p>Blend targets yourself and get the panel you need. Individual bead sets can be combined to build your own multiplex panel and use the ProcartaPlex Basic kit that contains all the reagents needed to run the assay.</p> </div> <div class="cmp-ctalist"> <div class="cmp-p-ctaitem"><div class="cmp-ctaitem" id="ctaitem-bd9f9b15b9"> <a class="cmp-ctaitem__anchor" href="/search/browse/category/us/en/90332032?filter=dimProductType_dim_ss%3aSimplex%20Kit"> <span class="cmp-ctaitem__icon icon-24-arrow-right-mono"></span> <span class="cmp-ctaitem__text">Search available Simplex Kits</span> </a> </div> </div> </div> </div> <div data-cmp-is="image" data-cmp-src="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Simplex-badge-v2.png" data-asset="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Simplex-badge-v2.png" data-title="Singleplex Assays icon" id="textimage-509685977" class="cmp-image " itemscope itemtype="http://schema.org/ImageObject"> <a class="cmp-image__link" href="/search/browse/category/us/en/90332032?filter=dimProductType_dim_ss%3aSimplex%20Kit" data-cmp-hook-image="link"> <noscript data-cmp-hook-image="noscript"> <img src="/content/dam/tfsite/images/storefront/luminex/procartaplex-immunoassays/Simplex-badge-v2.png" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Singleplex Assays icon" title="Singleplex Assays icon"/> </noscript> </a> <meta itemprop="caption" content="Singleplex Assays icon"/> </div>  </div> </div> </div> </div> </div> </div> </div> </div> <div class="cmp-p-container p-l1"> <div id="container-ac8e373449" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-textimage m--one-third-img aem-GridColumn aem-GridColumn--default--12"><div class="cmp-textimage cta-container" id="textimage-712993288" data-cmp-hook-cta="ctapanel"> <div class="cmp-textoverlay"> <div class="cmp-textoverlay__textwrapper"> <h2 class="cmp-textoverlay__title">Dual Reporter Panels</h2> <p><strong>NEW </strong>Explore the first-commercially available ProcartaPlex Dual Reporter assay that enables the simultaneous quantitation of the phosphorylated and total forms of up to 8 signaling proteins on the same bead.</p> </div> <div class="cmp-ctalist"> <div class="cmp-p-ctaitem"><div class="cmp-ctaitem" id="ctaitem-80428d6816"> <a class="cmp-ctaitem__anchor" href="/sg/en/home/life-science/antibodies/immunoassays/immunoassay-research-areas/cell-signaling-elisa-kits-immunoassays.html"> <span class="cmp-ctaitem__text">Learn more</span> </a> </div> </div> </div> </div> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/02/dual-reporter.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/02/dual-reporter.jpg" data-title="Illustration of an antibody binding to the cell surface and triggering a cell signaling cascade" id="textimage-712993288" class="cmp-image " itemscope itemtype="http://schema.org/ImageObject"> <a class="cmp-image__link" href="/sg/en/home/life-science/antibodies/immunoassays/immunoassay-research-areas/cell-signaling-elisa-kits-immunoassays.html" data-cmp-hook-image="link"> <noscript data-cmp-hook-image="noscript"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/02/dual-reporter.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Illustration of an antibody binding to the cell surface and triggering a cell signaling cascade"/> </noscript> </a> </div>  </div> </div> </div> </div> </div> <div class="cmp-p-separator"> <div id="separator-1a81de720d" class="cmp-separator"> <hr class="cmp-separator__horizontal-rule"/> </div> </div> <div class="cmp-p-container p-l1"> <div id="container-f04a60d4a3" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-sectiontitle aem-GridColumn aem-GridColumn--default--12"> <div id="sectiontitle-87d149e32c" class="cmp-sectiontitle"> <h2 id="procartaplex-assay" class="cmp-sectiontitle__text" data-anchor-nav-title="Why ProcartaPlex assays?">Why ProcartaPlex assays?</h2> </div> </div> <div class="cmp-p-container aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div id="container-49b33c6d89" class="cmp-container"> <div class="aem-Grid aem-Grid--default--6 "> <div class="cmp-p-text mt-l1 aem-GridColumn aem-GridColumn--default--6"> <div id="text-1395413386" class="cmp-text"> <p><strong>Flexibility</strong></p> <p>Get exactly the panel you want. More than 90% of ProcartaPlex assays can be combined with one another and allow for the creation of highly individual and high-plex panels (≤ 80-plex).</p> <p> </p> <p><strong>Reproducible results</strong></p> <p>Each ProcartaPlex assay is manufactured in an ISO 9001 certified facility and undergoes rigorous QC testing to help ensure reproducibility and lot-to-lot consistency.</p> <p> </p> <p><strong>Scalability</strong></p> <p>Achieve reproducible performances regardless of plex size and correlate data from differently sized panels and simplex kits.</p> </div> </div> </div> </div> </div> <div class="cmp-p-container aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div id="container-b587e69449" class="cmp-container"> <div class="aem-Grid aem-Grid--default--6 "> <div class="cmp-p-text mt-l1 aem-GridColumn aem-GridColumn--default--6"> <div id="text-1446542264" class="cmp-text"> <p><strong>High specificity and sensitivity</strong></p> <p>All ProcartaPlex assays are extensively and individually tested for specificity and detection of native endogenous protein as well as for combinability, interference, and cross-reactivity.</p> <p> </p> <p><strong>Save resources</strong></p> <p>ProcartaPlex multiplexing assays require smaller sample input and less hands-on time than single-analyte assays, helping reduce time to results, cost and labor.</p> <p> </p> <p><strong>Free analysis software</strong></p> <p>ProcartaPlex Analyst App is free software available through Thermo Fisher Connect with 1 TB of cloud storage at no charge.</p> </div> </div> </div> </div> </div> <div class="cmp-p-ctaitem aem-GridColumn aem-GridColumn--default--12"><div class="cmp-ctaitem" id="ctaitem-b86211eea7"> <a class="cmp-ctaitem__anchor" href="/sg/en/home/life-science/antibodies/immunoassays/procartaplex-assays-luminex/quantigene-plex-assays.html"> <span class="cmp-ctaitem__icon icon-24-arrow-right-mono"></span> <span class="cmp-ctaitem__text">Match ProcartaPlex with complementary and highly correlative QuantiGene Plex gene expression multiplex assays</span> </a> </div> </div> </div> </div> </div> <div class="cmp-p-container"> <div id="container-66ddc72ca3" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-title pl-l1 mt-l3 mb-l1 aem-GridColumn aem-GridColumn--default--12"><div id="title-25d9c18aae" class="cmp-title"> <h4 class="cmp-title__text">ProcartaPlex immunoassay data</h4> </div> </div> <div class="cmp-p-container p-l1 aem-GridColumn aem-GridColumn--default--12"> <div id="container-ee63fb7b7a" class="cmp-container"> <div class="cmp-p-textimage m--teaser"><div class="cmp-textimage cta-container" id="textimage-1408269219" data-cmp-hook-cta="ctapanel"> <div class="cmp-textoverlay"> <div class="cmp-textoverlay__textwrapper"> <h2 class="cmp-textoverlay__title">ProcartaPlex assay performance on Luminex xMAP INTELLIFLEX compared to Luminex 200 and FLEXMAP 3D</h2> <p><strong>(A)</strong> Human IL-8 standard curve data shows excellent correlation between INTELLIFLEX and established <a href="/sg/en/home/life-science/antibodies/immunoassays/procartaplex-assays-luminex/luminex-instruments.html">Luminex instruments</a>. Acquisition on INTELLIFLEX was done on low PMT mode (LPMTLX) to compare with Luminex 200 (LX200) and on high PMT mode (HPMTFM) to compare with FLEXMAP 3D (FM3D). <strong>(B)</strong> Human IL-8 total protein measurements from various samples (unstimulated and stimulated PBMCs) show excellent correlation and consistency when data was acquired on INTELLIFLEX vs Luminex 200 and FLEXMAP 3D. </p> </div> <div class="cmp-ctalist"> </div> </div> <div data-cmp-is="image" data-cmp-src="/content/dam/tfsite/images/storefront/luminex/resources/ProcartaPlex-immunoassay-results.png" data-asset="/content/dam/tfsite/images/storefront/luminex/resources/ProcartaPlex-immunoassay-results.png" data-title="IL-8 quantification with and without added stimulators (reported as mean fluorescence intensity) with ProcartaPlex immunoassays and Luminex instruments " id="textimage-1408269219" class="cmp-image " itemscope itemtype="http://schema.org/ImageObject"> <noscript data-cmp-hook-image="noscript"> <img src="/content/dam/tfsite/images/storefront/luminex/resources/ProcartaPlex-immunoassay-results.png" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="ProcartaPlex immunoassay results" title="IL-8 quantification with and without added stimulators (reported as mean fluorescence intensity) with ProcartaPlex immunoassays and Luminex instruments "/> </noscript> <meta itemprop="caption" content="IL-8 quantification with and without added stimulators (reported as mean fluorescence intensity) with ProcartaPlex immunoassays and Luminex instruments "/> </div>  </div> </div> </div> </div> </div> </div> </div> <div class="cmp-p-separator"> <div id="separator-46b2c084a3" class="cmp-separator"> <hr class="cmp-separator__horizontal-rule"/> </div> </div> <div class="cmp-p-container"> <div id="container-cc774dd8bc" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-accordion aem-GridColumn aem-GridColumn--default--12"><div id="accordion-de57c2125d" class="cmp-accordion" data-cmp-is="accordion"> <div class="cmp-accordion__item" data-cmp-hook-accordion="item" id="accordion-de57c2125d-item-459e8f7419"> <h2 class="cmp-accordion__header"> <button id="accordion-de57c2125d-item-459e8f7419-button" class="cmp-accordion__button" aria-controls="accordion-de57c2125d-item-459e8f7419-panel" data-cmp-hook-accordion="button"> <span class="cmp-accordion__title">Performance data</span> <span class="cmp-accordion__icon"></span> </button> </h2> <div data-cmp-hook-accordion="panel" id="accordion-de57c2125d-item-459e8f7419-panel" class="cmp-accordion__panel cmp-accordion__panel--hidden" role="region" aria-labelledby="accordion-de57c2125d-item-459e8f7419-button"><div class="cmp-p-container"> <div id="container-459e8f7419" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-title aem-GridColumn aem-GridColumn--default--12"><div id="title-19152dfbdf" class="cmp-title"> <h3 class="cmp-title__text">ProcartaPlex quality control standards</h3> </div> </div> <div class="cmp-p-text mt-l1 aem-GridColumn aem-GridColumn--default--12"> <div id="text-1570703336" class="cmp-text"> <p>All preconfigured multi-analyte reagent panels are extensively tested for combinability, interference, and cross-reactivity and go through stringent quality control standards.</p> <p> </p> </div> </div> <div class="cmp-p-container aem-GridColumn aem-GridColumn--default--12"> <div id="container-1d836d7362" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-text m--header aem-GridColumn aem-GridColumn--default--12"> <div id="text-585098301" class="cmp-text"> <table border="1" cellspacing="0" cellpadding="0" width="100%"> <tbody><tr><td width="35%"><p><strong>Specification</strong></p> </td> <td><p><strong>Description</strong></p> </td> </tr><tr><td><p><strong>Specificity</strong></p> </td> <td width="65%"><p>Proof of endogenous, native protein detection in specific samples</p> </td> </tr><tr><td><p><strong>Sensitivity</strong></p> </td> <td><p>Detection of relevant native protein levels</p> </td> </tr><tr><td><p><strong>Precision</strong></p> </td> <td><p>Inter-assay CV: <15%, Intra-assay CV: <15%</p> </td> </tr><tr><td><p><strong>Linearity of dilution</strong></p> </td> <td><p>Linear results over the range of the assay</p> </td> </tr><tr><td><p><strong>Lot-to-lot consistency</strong></p> </td> <td width="100%"><p>Each new batch is calibrated against the reference standard lot</p> </td> </tr><tr><td><p><strong>Dynamic range</strong></p> </td> <td width="100%"><p>Large dynamic range of all ProcartaPlex assays</p> </td> </tr></tbody></table> </div> </div> </div> </div> </div> <div class="cmp-p-container aem-GridColumn aem-GridColumn--default--12"> <div id="container-885e9c0819" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-image aem-GridColumn aem-GridColumn--default--12"> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procarta-plex-panel-table.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procarta-plex-panel-table.jpg" data-title="Cross-reactivity testing of analytes in ProcartaPlex preconfigured panels" id="image-1408592533" class="cmp-image hand-icon" itemscope itemtype="http://schema.org/ImageObject"> <div data-toggle="modal" data-target="#modal-image-1408592533" class="modal-toggle"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procarta-plex-panel-table.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Cross-reactivity testing of analytes in ProcartaPlex preconfigured panels"/> </div> </div>  <div class="cmp-image-modal modal" id="modal-image-1408592533" tabindex="-1" role="dialog" aria-labelledby="modal-label-for-image-1408592533"> <div class="cmp-image-modal__body modal-body"> <div class="cmp-image-modal__header modal-header no-border"> <button type="button" class="cmp-image-modal__close close" data-dismiss="modal" aria-label="Close"> <span class="cmp-image-modal__close__icon" aria-hidden="true">×</span> </button> </div>  <img loading="lazy" src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procarta-plex-panel-table.jpg" class="cmp-image-modal__body__image" itemprop="contentUrl" data-cmp-hook-image="image" alt="Cross-reactivity testing of analytes in ProcartaPlex preconfigured panels"/> </div> </div> </div> <div class="cmp-p-text mt-l1 aem-GridColumn aem-GridColumn--default--12"> <div id="text-1063260923" class="cmp-text"> <p><strong>Table 1.</strong> Cross-reactivity testing of analytes in ProcartaPlex preconfigured panels. Only a small subset of analytes are shown here.</p> </div> </div> </div> </div> </div> <div class="cmp-p-image aem-GridColumn aem-GridColumn--default--12"> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-comparison-data-65-80.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-comparison-data-65-80.jpg" data-title="Data illustrate the consistency in scalability between a large and small ProcartaPlex panel" id="image-967825524" class="cmp-image hand-icon" itemscope itemtype="http://schema.org/ImageObject"> <div data-toggle="modal" data-target="#modal-image-967825524" class="modal-toggle"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-comparison-data-65-80.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Data illustrate the consistency in scalability between a large and small ProcartaPlex panel"/> </div> </div>  <div class="cmp-image-modal modal" id="modal-image-967825524" tabindex="-1" role="dialog" aria-labelledby="modal-label-for-image-967825524"> <div class="cmp-image-modal__body modal-body"> <div class="cmp-image-modal__header modal-header no-border"> <button type="button" class="cmp-image-modal__close close" data-dismiss="modal" aria-label="Close"> <span class="cmp-image-modal__close__icon" aria-hidden="true">×</span> </button> </div>  <img loading="lazy" src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-comparison-data-65-80.jpg" class="cmp-image-modal__body__image" itemprop="contentUrl" data-cmp-hook-image="image" alt="Data illustrate the consistency in scalability between a large and small ProcartaPlex panel"/> </div> </div> </div> <div class="cmp-p-text mt-l1 aem-GridColumn aem-GridColumn--default--12"> <div id="text-859766430" class="cmp-text"> <p><strong>Figure 1. Scalability data to demonstrate reproducibility between ProcartaPlex panels of different size. </strong>Comparison of protein expression data from 42 human blood samples analyzed using the ProcartaPlex Human Immune Monitoring Panel, 65-Plex and the ProcartaPlex Human Immune Response Panel, 80-Plex<strong>.</strong> A selection of analytes is shown here. Similar results are obtained when investigating other analytes.</p> </div> </div> <div class="cmp-p-image aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--7 aem-GridColumn--offset--default--0"> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-mpc4.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-mpc4.jpg" data-title="Data demonstrates consistency of MCP-4 achieved in both large and small-scale ProcartaPlex Panel using human serum and stimulated plasma samples" id="image-642931105" class="cmp-image hand-icon" itemscope itemtype="http://schema.org/ImageObject"> <div data-toggle="modal" data-target="#modal-image-642931105" class="modal-toggle"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-mpc4.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Data demonstrates consistency of MCP-4 achieved in both large and small-scale ProcartaPlex Panel using human serum and stimulated plasma samples"/> </div> </div>  <div class="cmp-image-modal modal" id="modal-image-642931105" tabindex="-1" role="dialog" aria-labelledby="modal-label-for-image-642931105"> <div class="cmp-image-modal__body modal-body"> <div class="cmp-image-modal__header modal-header no-border"> <button type="button" class="cmp-image-modal__close close" data-dismiss="modal" aria-label="Close"> <span class="cmp-image-modal__close__icon" aria-hidden="true">×</span> </button> </div>  <img loading="lazy" src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-mpc4.jpg" class="cmp-image-modal__body__image" itemprop="contentUrl" data-cmp-hook-image="image" alt="Data demonstrates consistency of MCP-4 achieved in both large and small-scale ProcartaPlex Panel using human serum and stimulated plasma samples"/> </div> </div> </div> <div class="cmp-p-image aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--5 aem-GridColumn--offset--default--0"> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-correlation-mcp.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-correlation-mcp.jpg" data-title="Regression analysis comparing large and small-scale ProcartaPlex panel and measuring MCP-4" id="image-1457105938" class="cmp-image hand-icon" itemscope itemtype="http://schema.org/ImageObject"> <div data-toggle="modal" data-target="#modal-image-1457105938" class="modal-toggle"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-correlation-mcp.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Regression analysis comparing large and small-scale ProcartaPlex panel and 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data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-ccl1.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-ccl1.jpg" data-title="Data demonstrates consistency of CCL1 achieved in both large and small-scale ProcartaPlex Panel using human serum and stimulated plasma samples" id="image-1675634468" class="cmp-image hand-icon" itemscope itemtype="http://schema.org/ImageObject"> <div data-toggle="modal" data-target="#modal-image-1675634468" class="modal-toggle"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-ccl1.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Data demonstrates consistency of CCL1 achieved in both large and small-scale ProcartaPlex Panel using human serum and stimulated plasma samples"/> </div> </div>  <div class="cmp-image-modal modal" id="modal-image-1675634468" tabindex="-1" role="dialog" aria-labelledby="modal-label-for-image-1675634468"> <div class="cmp-image-modal__body modal-body"> <div class="cmp-image-modal__header modal-header no-border"> <button type="button" class="cmp-image-modal__close close" data-dismiss="modal" aria-label="Close"> <span class="cmp-image-modal__close__icon" aria-hidden="true">×</span> </button> </div>  <img loading="lazy" src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-sample-concentration-ccl1.jpg" class="cmp-image-modal__body__image" itemprop="contentUrl" data-cmp-hook-image="image" alt="Data demonstrates consistency of CCL1 achieved in both large and small-scale ProcartaPlex Panel using human serum and stimulated plasma samples"/> </div> </div> </div> <div class="cmp-p-image aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--5 aem-GridColumn--offset--default--0"> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-correlation-ccl1.jpg" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-correlation-ccl1.jpg" data-title="Regression analysis comparing large and small-scale ProcartaPlex panel and measuring CCL1" id="image-1765134370" class="cmp-image hand-icon" itemscope itemtype="http://schema.org/ImageObject"> <div data-toggle="modal" data-target="#modal-image-1765134370" class="modal-toggle"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2024/01/procartaplex-correlation-ccl1.jpg" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="Regression analysis comparing large and small-scale ProcartaPlex panel and measuring CCL1"/> </div> </div>  <div class="cmp-image-modal modal" id="modal-image-1765134370" tabindex="-1" role="dialog" aria-labelledby="modal-label-for-image-1765134370"> <div class="cmp-image-modal__body 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Data illustrates the high correlation between large and small-scale multiplex assays when using the ProcartaPlex assays. </strong>Regression analysis comparing the ProcartaPlex Chemokine Panel 2 (9-plex) and the ProcartaPlex Human Immune Response Panel, Immune Response Panel (80-plex) yielded an R<sup>2</sup> value >0.9. (0.99 for MCP-4, 0.93 for CCL1)</p> </div> </div> </div> </div> </div> </div> </div> <div class="cmp-accordion__item" data-cmp-hook-accordion="item" id="accordion-de57c2125d-item-382e30cdf4"> <h2 class="cmp-accordion__header"> <button id="accordion-de57c2125d-item-382e30cdf4-button" class="cmp-accordion__button" aria-controls="accordion-de57c2125d-item-382e30cdf4-panel" data-cmp-hook-accordion="button"> <span class="cmp-accordion__title">ProcartaPlex workflow</span> <span class="cmp-accordion__icon"></span> </button> </h2> <div data-cmp-hook-accordion="panel" id="accordion-de57c2125d-item-382e30cdf4-panel" class="cmp-accordion__panel cmp-accordion__panel--hidden" role="region" aria-labelledby="accordion-de57c2125d-item-382e30cdf4-button"><div class="cmp-p-container"> <div id="container-382e30cdf4" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-textimage aem-GridColumn aem-GridColumn--default--12"><div class="cmp-textimage cta-container" id="textimage-1855292891" data-cmp-hook-cta="ctapanel"> <div class="cmp-textoverlay"> <div class="cmp-textoverlay__textwrapper"> <h2 class="cmp-textoverlay__title"></h2> <p><strong>Figure 3. Workflow of ProcartaPlex multiplex immunoassay</strong></p> <p>ProcartaPlex multiplex immunoassays for the Luminex platform are performed in a similar way to traditional ELISAs but with the ability to quantitate up to 80 targets simultaneously in a single well. The steps are similar, with the exception that antibody-coated beads are used to capture the analyte, instead of having capture antibodies attached directly to the plate. Each kit provides standards of known concentration so that a standard curve can be established. After incubation on a shaker, the beads are washed by putting the 96-well plate on a flat magnet for 30 seconds, after which the fluid is discarded by flicking the wells or by using an automated plate washer. The magnet is removed, and the beads are resuspended in the detection antibody. Another incubation and wash are followed by the addition of streptavidin–R-phycoerythrin (SAPE). The beads are then washed and are ready to analyze. <a></a><a href="/sg/en/home/life-science/antibodies/immunoassays/procartaplex-assays-luminex/procartaplex-immunoassays/procartaplex-analyst-software">Streamline your data analysis with the ProcartaPlex Analysis App</a>.</p> </div> </div> <div data-cmp-is="image" data-cmp-src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2023/12/ProcartaPlex-workflow-schematic.png" data-asset="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2023/12/ProcartaPlex-workflow-schematic.png" data-title="General workflow for the Invitrogen ProcartaPlex multiplex immunoassay" id="textimage-1855292891" class="cmp-image " itemscope itemtype="http://schema.org/ImageObject"> <noscript data-cmp-hook-image="noscript"> <img src="/content/dam/LifeTech/global/life-sciences/bid/pca-ais/2023/12/ProcartaPlex-workflow-schematic.png" class="cmp-image__image" loading="lazy" itemprop="contentUrl" data-cmp-hook-image="image" alt="General workflow for the Invitrogen ProcartaPlex multiplex immunoassay"/> </noscript> </div>  </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="cmp-p-separator"> <div id="separator-bfb88305ff" class="cmp-separator"> <hr class="cmp-separator__horizontal-rule"/> </div> </div> <div class="cmp-p-container"> <div id="container-d08f2cf7f6" class="cmp-container"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-p-testimonial aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-testimonial cta-container" data-cmp-hook-cta="ctapanel"> <div class="cmp-testimonial__message"> <p>“Our core facility has been using the Invitrogen Th1/Th2 Cytokine 36-Plex Mouse ProcartaPlex Panel on tissue lysates. 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