<?xml version="1.0" encoding="UTF-8"?> <article key="pdf/2527" mdate="2013-06-23 00:00:00"> <author>Ndeye Rokhaya Faye and Ibtissem Gammoudi and Fabien Morot茅 and Christine Grauby-Heywang and TouriaCohen-Bouhacina</author> <title>Phase Behavior and Structure Properties of Supported Lipid Monolayers and Bilayers in Interaction with Silica Nanoparticles</title> <pages>441 - 448</pages> <year>2013</year> <volume>7</volume> <number>6</number> <journal>International Journal of Biotechnology and Bioengineering</journal> <ee>https://publications.waset.org/pdf/2527</ee> <url>https://publications.waset.org/vol/78</url> <publisher>World Academy of Science, Engineering and Technology</publisher> <abstract>In this study we investigate silica nanoparticle (SiO2 NP) effects on the structure and phase properties of supported lipid monolayers and bilayers, coupling surface pressure measurements, fluorescence microscopy and atomic force microscopy. SiO2NPs typically in size range of 10nm to 100 nm in diameter are tested. Our results suggest first that lipid molecules organization depends to their nature. Secondly, lipid molecules in the vinicity of big aggregates nanoparticles organize in liquid condensed phase whereas small aggregates are localized in both fluid liquidexpanded (LE) and liquidcondenced (LC). We demonstrated also by atomic force microscopy that by measuring friction forces it is possible to get information as if nanoparticle aggregates are recovered or not by lipid monolayers and bilayers. </abstract> <index>Open Science Index 78, 2013</index> </article>