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Search results for: turnaround time

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text-center" style="font-size:1.6rem;">Search results for: turnaround time</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18168</span> Simplifying Health Risk Assessment (HRA) and Its Operationalisation for Turnaround Activities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Thirumila%20Muthukamaru">Thirumila Muthukamaru</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The objective of a Health Risk Assessment (HRA) is to achieve a quality evaluation of risk assessments in a timely manner where adequate controls can be in place to protect workers health, especially during turnarounds where the exposure to health hazards is expected to rise during the performance of the many activities that take place, exposing workers to health risk. HRA development requires a competent team comprising experienced subject matter experts in the field, such as Industrial hygienists, Occupational Health Doctors, Turnaround Coordinators, Operation / Maintenance personnel, etc. The conventional way of conducting HRA is not only tedious and time-consuming but also less appreciated when it is not interpreted correctly, which may contribute to inadequate operationalization of it. Simplification can be the essence of timely intervention in managing health risks. This paper is intended as a sharing of the approach taken to simplify the methodology of developing the HRA report and operationalizing it. The approach includes developing a Generic HRA for turnaround activities to be used as a reference document and the empowerment of identified personnel through upskilling sessions to take up the role of facilitating HRA sessions. This empowerment is one of the key approaches towards the successful translation of the HRA into specific turnaround Job Hazard Analysis (JHA) that embed it in the Permit to Work (PTW) process. The approach used here increases awareness and compliance on HRA for turnaround activities through better interpretation and operationalization of the HRA report, adding value to the risk assessment for turnaround activities. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=industrial%20hygiene" title="industrial hygiene">industrial hygiene</a>, <a href="https://publications.waset.org/abstracts/search?q=health%20risk%20assessment" title=" health risk assessment"> health risk assessment</a>, <a href="https://publications.waset.org/abstracts/search?q=HRA" title=" HRA"> HRA</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20assessment" title=" risk assessment"> risk assessment</a> </p> <a href="https://publications.waset.org/abstracts/182191/simplifying-health-risk-assessment-hra-and-its-operationalisation-for-turnaround-activities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/182191.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">47</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18167</span> An Approach for Determining and Reducing Vehicle Turnaround Time for Outbound Logistics by Using Critical Path Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Prajakta%20M.%20Wazat">Prajakta M. Wazat</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20N.%20Raut"> D. N. Raut</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The study consists of a fast moving consumer goods (FMCG) beverage company wherein a portion of the supply chain which deals with outbound logistics is taken for improvement in order to reduce its logistics cost by using critical path method (CPM) method. Logistics is a major portion of the supply chain where customers are not willing to pay as it adds cost to product without adding value. In this study, it is necessary to ensure that products are delivered to clients at the right time while preserving high-quality standards from the beginning to the end of the supply chain. CPM is a logical sequencing method where in the most efficient route is achieved by arranging the series of events. CPM enables to identify a critical factor in order to minimize the delays and interruption by providing a feasible solution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=FMCG" title="FMCG">FMCG</a>, <a href="https://publications.waset.org/abstracts/search?q=supply%20chain" title=" supply chain"> supply chain</a>, <a href="https://publications.waset.org/abstracts/search?q=outbound%20logistics" title=" outbound logistics"> outbound logistics</a>, <a href="https://publications.waset.org/abstracts/search?q=vehicle%20turnaround%20time" title=" vehicle turnaround time"> vehicle turnaround time</a>, <a href="https://publications.waset.org/abstracts/search?q=critical%20path%20method" title=" critical path method"> critical path method</a>, <a href="https://publications.waset.org/abstracts/search?q=cost%20reduction" title=" cost reduction"> cost reduction</a> </p> <a href="https://publications.waset.org/abstracts/98738/an-approach-for-determining-and-reducing-vehicle-turnaround-time-for-outbound-logistics-by-using-critical-path-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98738.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">165</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18166</span> Physical Verification Flow on Multiple Foundries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rohaya%20Abdul%20Wahab">Rohaya Abdul Wahab</a>, <a href="https://publications.waset.org/abstracts/search?q=Raja%20Mohd%20Fuad%20Tengku%20Aziz"> Raja Mohd Fuad Tengku Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazaliza%20Othman"> Nazaliza Othman</a>, <a href="https://publications.waset.org/abstracts/search?q=Sharifah%20Saleh"> Sharifah Saleh</a>, <a href="https://publications.waset.org/abstracts/search?q=Nabihah%20Razali"> Nabihah Razali</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Al%20Baqir%20Zinal%20Abidin"> Muhammad Al Baqir Zinal Abidin</a>, <a href="https://publications.waset.org/abstracts/search?q=Md%20Hanif%20Md%20Nasir"> Md Hanif Md Nasir </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper will discuss how we optimize our physical verification flow in our IC Design Department having various rule decks from multiple foundries. Our ultimate goal is to achieve faster time to tape-out and avoid schedule delay. Currently the physical verification runtimes and memory usage have drastically increased with the increasing number of design rules, design complexity and the size of the chips to be verified. To manage design violations, we use a number of solutions to reduce the amount of violations needed to be checked by physical verification engineers. The most important functions in physical verifications are DRC (design rule check), LVS (layout vs. schematic) and XRC (extraction). Since we have a multiple number of foundries for our design tape-outs, we need a flow that improve the overall turnaround time and ease of use of the physical verification process. The demand for fast turnaround time is even more critical since the physical design is the last stage before sending the layout to the foundries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=physical%20verification" title="physical verification">physical verification</a>, <a href="https://publications.waset.org/abstracts/search?q=DRC" title=" DRC"> DRC</a>, <a href="https://publications.waset.org/abstracts/search?q=LVS" title=" LVS"> LVS</a>, <a href="https://publications.waset.org/abstracts/search?q=XRC" title=" XRC"> XRC</a>, <a href="https://publications.waset.org/abstracts/search?q=flow" title=" flow"> flow</a>, <a href="https://publications.waset.org/abstracts/search?q=foundry" title=" foundry"> foundry</a>, <a href="https://publications.waset.org/abstracts/search?q=runset" title=" runset"> runset</a> </p> <a href="https://publications.waset.org/abstracts/29033/physical-verification-flow-on-multiple-foundries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29033.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">654</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18165</span> Enhancing the Implementation Strategy of Simultaneous Operations (SIMOPS) for the Major Turnaround at Pertamina Plaju Refinery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fahrur%20Rozi">Fahrur Rozi</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniswara%20Krisna%20Prabatha"> Daniswara Krisna Prabatha</a>, <a href="https://publications.waset.org/abstracts/search?q=Latief%20Zulfikar%20Chusaini"> Latief Zulfikar Chusaini</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Amidst the backdrop of Pertamina Plaju Refinery, which stands as the oldest and historically less technologically advanced among Pertamina's refineries, lies a unique challenge. Originally integrating facilities established by Shell in 1904 and Stanvac (originally Standard Oil) in 1926, the primary challenge at Plaju Refinery does not solely revolve around complexity; instead, it lies in ensuring reliability, considering its operational history of over a century. After centuries of existence, Plaju Refinery has never undergone a comprehensive major turnaround encompassing all its units. The usual practice involves partial turnarounds that are sequentially conducted across its primary, secondary, and tertiary units (utilities and offsite). However, a significant shift is on the horizon. In the Q-IV of 2023, the refinery embarks on its first-ever major turnaround since its establishment. This decision was driven by the alignment of maintenance timelines across various units. Plaju Refinery's major turnaround was scheduled for October-November 2023, spanning 45 calendar days, with the objective of enhancing the operational reliability of all refinery units. The extensive job list for this turnaround encompasses 1583 tasks across 18 units/areas, involving approximately 9000 contracted workers. In this context, the Strategy of Simultaneous Operations (SIMOPS) execution emerges as a pivotal tool to optimize time efficiency and ensure safety. A Hazard Effect Management Process (HEMP) has been employed to assess the risk ratings of each task within the turnaround. Out of the tasks assessed, 22 are deemed high-risk and necessitate mitigation. The SIMOPS approach serves as a preventive measure against potential incidents. It is noteworthy that every turnaround period at Pertamina Plaju Refinery involves SIMOPS-related tasks. In this context, enhancing the implementation strategy of "Simultaneous Operations (SIMOPS)" becomes imperative to minimize the occurrence of incidents. At least four improvements have been introduced in the enhancement process for the major turnaround at Refinery Plaju. The first improvement involves conducting systematic risk assessment and potential hazard mitigation studies for SIMOPS tasks before task execution, as opposed to the previous on-site approach. The second improvement includes the completion of SIMOPS Job Mitigation and Work Matrices Sheets, which was often neglected in the past. The third improvement emphasizes comprehensive awareness to workers/contractors regarding potential hazards and mitigation strategies for SIMOPS tasks before and during the major turnaround. The final improvement is the introduction of a daily program for inspecting and observing work in progress for SIMOPS tasks. Prior to these improvements, there was no established program for monitoring ongoing activities related to SIMOPS tasks during the turnaround. This study elucidates the steps taken to enhance SIMOPS within Pertamina, drawing from the experiences of Plaju Refinery as a guide. A real actual case study will be provided from our experience in the operational unit. In conclusion, these efforts are essential for the success of the first-ever major turnaround at Plaju Refinery, with the SIMOPS strategy serving as a central component. Based on these experiences, enhancements have been made to Pertamina's official Internal Guidelines for Executing SIMOPS Risk Mitigation, benefiting all Pertamina units. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=process%20safety%20management" title="process safety management">process safety management</a>, <a href="https://publications.waset.org/abstracts/search?q=turn%20around" title=" turn around"> turn around</a>, <a href="https://publications.waset.org/abstracts/search?q=oil%20refinery" title=" oil refinery"> oil refinery</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20assessment" title=" risk assessment"> risk assessment</a> </p> <a href="https://publications.waset.org/abstracts/178892/enhancing-the-implementation-strategy-of-simultaneous-operations-simops-for-the-major-turnaround-at-pertamina-plaju-refinery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/178892.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">74</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18164</span> Incorporating Priority Round-Robin Scheduler to Sustain Indefinite Blocking Issue and Prioritized Processes in Operating System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Heng%20Chia%20Ying">Heng Chia Ying</a>, <a href="https://publications.waset.org/abstracts/search?q=Charmaine%20Tan%20Chai%20Nie"> Charmaine Tan Chai Nie</a>, <a href="https://publications.waset.org/abstracts/search?q=Burra%20Venkata%20Durga%20Kumar"> Burra Venkata Durga Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Process scheduling is the method of process management that determines which process the CPU will proceed with for the next task and how long it takes. Some issues were found in process management, particularly for Priority Scheduling (PS) and Round Robin Scheduling (RR). The proposed recommendations made for IPRRS are to combine the strengths of both into a combining algorithm while they draw on others to compensate for each weakness. A significant improvement on the combining technique of scheduler, Incorporating Priority Round-Robin Scheduler (IPRRS) address an algorithm for both high and low priority task to sustain the indefinite blocking issue faced in the priority scheduling algorithm and minimize the average turnaround time (ATT) and average waiting time (AWT) in RR scheduling algorithm. This paper will delve into the simple rules introduced by IPRRS and enhancements that both PS and RR bring to the execution of processes in the operating system. Furthermore, it incorporates the best aspects of each algorithm to build the optimum algorithm for a certain case in terms of prioritized processes, ATT, and AWT. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=round%20Robin%20scheduling" title="round Robin scheduling">round Robin scheduling</a>, <a href="https://publications.waset.org/abstracts/search?q=priority%20scheduling" title=" priority scheduling"> priority scheduling</a>, <a href="https://publications.waset.org/abstracts/search?q=indefinite%20blocking" title=" indefinite blocking"> indefinite blocking</a>, <a href="https://publications.waset.org/abstracts/search?q=process%20management" title=" process management"> process management</a>, <a href="https://publications.waset.org/abstracts/search?q=sustain" title=" sustain"> sustain</a>, <a href="https://publications.waset.org/abstracts/search?q=turnaround%20time" title=" turnaround time"> turnaround time</a> </p> <a href="https://publications.waset.org/abstracts/160706/incorporating-priority-round-robin-scheduler-to-sustain-indefinite-blocking-issue-and-prioritized-processes-in-operating-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/160706.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">148</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18163</span> Improving Grade Control Turnaround Times with In-Pit Hyperspectral Assaying</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gary%20Pattemore">Gary Pattemore</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Edgar"> Michael Edgar</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20Job"> Andrew Job</a>, <a href="https://publications.waset.org/abstracts/search?q=Marina%20Auad"> Marina Auad</a>, <a href="https://publications.waset.org/abstracts/search?q=Kathryn%20Job"> Kathryn Job</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As critical commodities become more scarce, significant time and resources have been used to better understand complicated ore bodies and extract their full potential. These challenging ore bodies provide several pain points for geologists and engineers to overcome, poor handling of these issues flows downs stream to the processing plant affecting throughput rates and recovery. Many open cut mines utilise blast hole drilling to extract additional information to feed back into the modelling process. This method requires samples to be collected during or after blast hole drilling. Samples are then sent for assay with turnaround times varying from 1 to 12 days. This method is time consuming, costly, requires human exposure on the bench and collects elemental data only. To address this challenge, research has been undertaken to utilise hyperspectral imaging across a broad spectrum to scan samples, collars or take down hole measurements for minerals and moisture content and grade abundances. Automation of this process using unmanned vehicles and on-board processing reduces human in pit exposure to ensure ongoing safety. On-board processing allows data to be integrated into modelling workflows with immediacy. The preliminary results demonstrate numerous direct and indirect benefits from this new technology, including rapid and accurate grade estimates, moisture content and mineralogy. These benefits allow for faster geo modelling updates, better informed mine scheduling and improved downstream blending and processing practices. The paper presents recommendations for implementation of the technology in open cut mining environments. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=grade%20control" title="grade control">grade control</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperspectral%20scanning" title=" hyperspectral scanning"> hyperspectral scanning</a>, <a href="https://publications.waset.org/abstracts/search?q=artificial%20intelligence" title=" artificial intelligence"> artificial intelligence</a>, <a href="https://publications.waset.org/abstracts/search?q=autonomous%20mining" title=" autonomous mining"> autonomous mining</a>, <a href="https://publications.waset.org/abstracts/search?q=machine%20learning" title=" machine learning"> machine learning</a> </p> <a href="https://publications.waset.org/abstracts/146664/improving-grade-control-turnaround-times-with-in-pit-hyperspectral-assaying" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146664.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">113</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18162</span> A Rapid Colorimetric Assay for Direct Detection of Unamplified Hepatitis C Virus RNA Using Gold Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Shemis">M. Shemis</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20Maher"> O. Maher</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Casterou"> G. Casterou</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Gauffre"> F. Gauffre</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hepatitis C virus (HCV) is a major cause of chronic liver disease with a global 170 million chronic carriers at risk of developing liver cirrhosis and/or liver cancer. Egypt reports the highest prevalence of HCV worldwide. Currently, two classes of assays are used in the diagnosis and management of HCV infection. Despite the high sensitivity and specificity of the available diagnostic assays, they are time-consuming, labor-intensive, expensive, and require specialized equipment and highly qualified personal. It is therefore important for clinical and economic terms to develop a low-tech assay for the direct detection of HCV RNA with acceptable sensitivity and specificity, short turnaround time, and cost-effectiveness. Such an assay would be critical to control HCV in developing countries with limited resources and high infection rates, such as Egypt. The unique optical and physical properties of gold nanoparticles (AuNPs) have allowed the use of these nanoparticles in developing simple and rapid colorimetric assays for clinical diagnosis offering higher sensitivity and specificity than current detection techniques. The current research aims to develop a detection assay for HCV RNA using gold nanoparticles (AuNPs). Methods: 200 anti-HCV positive samples and 50 anti-HCV negative plasma samples were collected from Egyptian patients. HCV viral load was quantified using m2000rt (Abbott Molecular Inc., Des Plaines, IL). HCV genotypes were determined using multiplex nested RT- PCR. The assay is based on the aggregation of AuNPs in presence of the target RNA. Aggregation of AuNPs causes a color shift from red to blue. AuNPs were synthesized using citrate reduction method. Different sets of probes within the 5’ UTR conserved region of the HCV genome were designed, grafted on AuNPs and optimized for the efficient detection of HCV RNA. Results: The nano-gold assay could colorimetrically detect HCV RNA down to 125 IU/ml with sensitivity and specificity of 91.1% and 93.8% respectively. The turnaround time of the assay is < 30 min. Conclusions: The assay allows sensitive and rapid detection of HCV RNA and represents an inexpensive and simple point-of-care assay for resource-limited settings. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=HCV" title="HCV">HCV</a>, <a href="https://publications.waset.org/abstracts/search?q=gold%20nanoparticles" title=" gold nanoparticles"> gold nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=point%20of%20care" title=" point of care"> point of care</a>, <a href="https://publications.waset.org/abstracts/search?q=viral%20load" title=" viral load"> viral load</a> </p> <a href="https://publications.waset.org/abstracts/75487/a-rapid-colorimetric-assay-for-direct-detection-of-unamplified-hepatitis-c-virus-rna-using-gold-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/75487.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">206</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18161</span> Process Improvement and Redesign of the Immuno Histology (IHC) Lab at MSKCC: A Lean and Ergonomic Study </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samantha%20Meyerholz">Samantha Meyerholz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> MSKCC offers patients cutting edge cancer care with the highest quality standards. However, many patients and industry members do not realize that the operations of the Immunology Histology Lab (IHC) are the backbone for carrying out this mission. The IHC lab manufactures blocks and slides containing critical tissue samples that will be read by a Pathologist to diagnose and dictate a patient’s treatment course. The lab processes 200 requests daily, leading to the generation of approximately 2,000 slides and 1,100 blocks each day. Lab material is transported through labeling, cutting, staining and sorting manufacturing stations, while being managed by multiple techs throughout the space. The quality of the stain as well as wait times associated with processing requests, is directly associated with patients receiving rapid treatments and having a wider range of care options. This project aims to improve slide request turnaround time for rush and non-rush cases, while increasing the quality of each request filled (no missing slides or poorly stained items). Rush cases are to be filled in less than 24 hours, while standard cases are allotted a 48 hour time period. Reducing turnaround times enable patients to communicate sooner with their clinical team regarding their diagnosis, ultimately leading faster treatments and potentially better outcomes. Additional project goals included streamlining tech and material workflow, while reducing waste and increasing efficiency. This project followed a DMAIC structure with emphasis on lean and ergonomic principles that could be integrated into an evolving lab culture. Load times and batching processes were analyzed using process mapping, FMEA analysis, waste analysis, engineering observation, 5S and spaghetti diagramming. Reduction of lab technician movement as well as their body position at each workstation was of top concern to pathology leadership. With new equipment being brought into the lab to carry out workflow improvements, screen and tool placement was discussed with the techs in focus groups, to reduce variation and increase comfort throughout the workspace. 5S analysis was completed in two phases in the IHC lab, helping to drive solutions that reduced rework and tech motion. The IHC lab plans to continue utilizing these techniques to further reduce the time gap between tissue analysis and cancer care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=engineering" title="engineering">engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=ergonomics" title=" ergonomics"> ergonomics</a>, <a href="https://publications.waset.org/abstracts/search?q=healthcare" title=" healthcare"> healthcare</a>, <a href="https://publications.waset.org/abstracts/search?q=lean" title=" lean"> lean</a> </p> <a href="https://publications.waset.org/abstracts/58748/process-improvement-and-redesign-of-the-immuno-histology-ihc-lab-at-mskcc-a-lean-and-ergonomic-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58748.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">223</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18160</span> Direct Phoenix Identification and Antimicrobial Susceptibility Testing from Positive Blood Culture Broths</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Waad%20Al%20Saleemi">Waad Al Saleemi</a>, <a href="https://publications.waset.org/abstracts/search?q=Badriya%20Al%20Adawi"> Badriya Al Adawi</a>, <a href="https://publications.waset.org/abstracts/search?q=Zaaima%20Al%20Jabri"> Zaaima Al Jabri</a>, <a href="https://publications.waset.org/abstracts/search?q=Sahim%20Al%20Ghafri"> Sahim Al Ghafri</a>, <a href="https://publications.waset.org/abstracts/search?q=Jalila%20Al%20Hadhramia"> Jalila Al Hadhramia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: Using standard lab methods, a positive blood culture requires a minimum of two days (two occasions of overnight incubation) to obtain a final identification (ID) and antimicrobial susceptibility results (AST) report. In this study, we aimed to evaluate the accuracy and precision of identification and antimicrobial susceptibility testing of an alternative method (direct method) that will reduce the turnaround time by 24 hours. This method involves the direct inoculation of positive blood culture broths into the Phoenix system using serum separation tubes (SST). Method: This prospective study included monomicrobial-positive blood cultures obtained from January 2022 to May 2023 in SQUH. Blood cultures containing a mixture of organisms, fungi, or anaerobic organisms were excluded from this study. The result of the new “direct method” under study was compared with the current “standard method” used in the lab. The accuracy and precision were evaluated for the ID and AST using Clinical and Laboratory Standards Institute (CLSI) recommendations. The categorical agreement, essential agreement, and the rates of very major errors (VME), major errors (ME), and minor errors (MIE) for both gram-negative and gram-positive bacteria were calculated. Passing criteria were set according to CLSI. Result: The results of ID and AST were available for a total of 158 isolates. Of 77 isolates of gram-negative bacteria, 71 (92%) were correctly identified at the species level. Of 70 isolates of gram-positive bacteria, 47(67%) isolates were correctly identified. For gram-negative bacteria, the essential agreement of the direct method was ≥92% when compared to the standard method, while the categorical agreement was ≥91% for all tested antibiotics. The precision of ID and AST were noted to be 100% for all tested isolates. For gram-positive bacteria, the essential agreement was >93%, while the categorical agreement was >92% for all tested antibiotics except moxifloxacin. Many antibiotics were noted to have an unacceptable higher rate of very major errors including penicillin, cotrimoxazole, clindamycin, ciprofloxacin, and moxifloxacin. However, no error was observed in the results of vancomycin, linezolid, and daptomycin. Conclusion: The direct method of ID and AST for positive blood cultures using SST is reliable for gram negative bacteria. It will significantly decrease the turnaround time and will facilitate antimicrobial stewardship. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bloodstream%20infection" title="bloodstream infection">bloodstream infection</a>, <a href="https://publications.waset.org/abstracts/search?q=oman" title=" oman"> oman</a>, <a href="https://publications.waset.org/abstracts/search?q=direct%20ast" title=" direct ast"> direct ast</a>, <a href="https://publications.waset.org/abstracts/search?q=blood%20culture" title=" blood culture"> blood culture</a>, <a href="https://publications.waset.org/abstracts/search?q=rapid%20identification" title=" rapid identification"> rapid identification</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20susceptibility" title=" antimicrobial susceptibility"> antimicrobial susceptibility</a>, <a href="https://publications.waset.org/abstracts/search?q=phoenix" title=" phoenix"> phoenix</a>, <a href="https://publications.waset.org/abstracts/search?q=direct%20inoculation" title=" direct inoculation"> direct inoculation</a> </p> <a href="https://publications.waset.org/abstracts/182053/direct-phoenix-identification-and-antimicrobial-susceptibility-testing-from-positive-blood-culture-broths" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/182053.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">64</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18159</span> A Contribution to Blockchain Privacy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Malika%20Yaici">Malika Yaici</a>, <a href="https://publications.waset.org/abstracts/search?q=Feriel%20Lalaoui"> Feriel Lalaoui</a>, <a href="https://publications.waset.org/abstracts/search?q=Lydia%20Belhoul"> Lydia Belhoul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As a new distributed point-to-point (P2P) technology, blockchain has become a very broad field of research, addressing various challenges, including privacy preserving, as is the case in all other technologies. In this work, a study of the existing solutions to the problems related to private life in general and in blockchains in particular is performed. User anonymity and transaction confidentiality are the two main challenges to the protection of privacy in blockchains. Mixing mechanisms and cryptographic solutions respond to this problem but remain subject to attacks and suffer from shortcomings. Taking into account these imperfections and the synthesis of our study, we present a mixing model without trusted third parties, based on group signatures, allowing reinforcing the anonymity of the users, the confidentiality of the transactions, with minimal turnaround time and without mixing costs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anonymity" title="anonymity">anonymity</a>, <a href="https://publications.waset.org/abstracts/search?q=blockchain" title=" blockchain"> blockchain</a>, <a href="https://publications.waset.org/abstracts/search?q=mixing%20coins" title=" mixing coins"> mixing coins</a>, <a href="https://publications.waset.org/abstracts/search?q=privacy" title=" privacy"> privacy</a> </p> <a href="https://publications.waset.org/abstracts/194226/a-contribution-to-blockchain-privacy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194226.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">12</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18158</span> Introduction of Digital Radiology to Improve the Timeliness in Availability of Radiological Diagnostic Images for Trauma Care</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anuruddha%20Jagoda">Anuruddha Jagoda</a>, <a href="https://publications.waset.org/abstracts/search?q=Samiddhi%20Samarakoon"> Samiddhi Samarakoon</a>, <a href="https://publications.waset.org/abstracts/search?q=Anil%20Jasinghe"> Anil Jasinghe</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In an emergency department ‘where every second count for patient’s management’ timely availability of X- rays play a vital role in early diagnosis and management of patients. Trauma care centers rely heavily on timely radiologic imaging for patient care and radiology plays a crucial role in the emergency department (ED) operations. A research study was carried out to assess timeliness of availability of X-rays and total turnaround time at the Accident Service of National Hospital of Sri Lanka which is the premier trauma center in the country. Digital Radiology system was implemented as an intervention to improve the timeliness of availability of X-rays. Post-implementation assessment was carried out to assess the effectiveness of the intervention. Reduction in all three aspects of waiting times namely waiting for initial examination by doctors, waiting until X –ray is performed and waiting for image availability was observed after implementation of the intervention. However, the most significant improvement was seen in waiting time for image availability and reduction in time for image availability had indirect impact on reducing waiting time for initial examination by doctors and waiting until X –ray is performed. The most significant reduction in time for image availability was observed when performing 4-5 X rays with DR system. The least improvement in timeliness was seen in patients who are categorized as critical. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=emergency%20department" title="emergency department">emergency department</a>, <a href="https://publications.waset.org/abstracts/search?q=digital%20radilogy" title=" digital radilogy"> digital radilogy</a>, <a href="https://publications.waset.org/abstracts/search?q=timeliness" title=" timeliness"> timeliness</a>, <a href="https://publications.waset.org/abstracts/search?q=trauma%20care" title=" trauma care"> trauma care</a> </p> <a href="https://publications.waset.org/abstracts/56328/introduction-of-digital-radiology-to-improve-the-timeliness-in-availability-of-radiological-diagnostic-images-for-trauma-care" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56328.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">265</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18157</span> Pod and Wavelets Application for Aerodynamic Design Optimization</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bonchan%20Koo">Bonchan Koo</a>, <a href="https://publications.waset.org/abstracts/search?q=Junhee%20Han"> Junhee Han</a>, <a href="https://publications.waset.org/abstracts/search?q=Dohyung%20Lee"> Dohyung Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The research attempts to evaluate the accuracy and efficiency of a design optimization procedure which combines wavelets-based solution algorithm and proper orthogonal decomposition (POD) database management technique. Aerodynamic design procedure calls for high fidelity computational fluid dynamic (CFD) simulations and the consideration of large number of flow conditions and design constraints. Even with significant computing power advancement, current level of integrated design process requires substantial computing time and resources. POD reduces the degree of freedom of full system through conducting singular value decomposition for various field simulations. For additional efficiency improvement of the procedure, adaptive wavelet technique is also being employed during POD training period. The proposed design procedure was applied to the optimization of wing aerodynamic performance. Throughout the research, it was confirmed that the POD/wavelets design procedure could significantly reduce the total design turnaround time and is also able to capture all detailed complex flow features as in full order analysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=POD%20%28Proper%20Orthogonal%20Decomposition%29" title="POD (Proper Orthogonal Decomposition)">POD (Proper Orthogonal Decomposition)</a>, <a href="https://publications.waset.org/abstracts/search?q=wavelets" title=" wavelets"> wavelets</a>, <a href="https://publications.waset.org/abstracts/search?q=CFD" title=" CFD"> CFD</a>, <a href="https://publications.waset.org/abstracts/search?q=design%20optimization" title=" design optimization"> design optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=ROM%20%28Reduced%20Order%20Model%29" title=" ROM (Reduced Order Model)"> ROM (Reduced Order Model)</a> </p> <a href="https://publications.waset.org/abstracts/21466/pod-and-wavelets-application-for-aerodynamic-design-optimization" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21466.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">467</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18156</span> Computational Fluid Dynamics (CFD) Simulation Approach for Developing New Powder Dispensing Device</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Revanth%20Rallapalli">Revanth Rallapalli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Manually dispensing solids and powders can be difficult as it requires gradually pour and check the amount on the scale to be dispensed. Current systems are manual and non-continuous in nature and are user-dependent and difficult to control powder dispensation. Recurrent dosing of powdered medicines in precise amounts quickly and accurately has been an all-time challenge. Various new powder dispensing mechanisms are being designed to overcome these challenges. A battery-operated screw conveyor mechanism is being innovated to overcome the above problems faced. These inventions are numerically evaluated at the concept development level by employing Computational Fluid Dynamics (CFD) of gas-solids multiphase flow systems. CFD has been very helpful in development of such devices saving time and money by reducing the number of prototypes and testing. Furthermore, this paper describes a simulation of powder dispensation from the trocar’s end by considering the powder as secondary flow in air, is simulated by using the technique called Dense Discrete Phase Model incorporated with Kinetic Theory of Granular Flow (DDPM-KTGF). By considering the volume fraction of powder as 50%, the transportation of powder from the inlet side to trocar’s end side is done by rotation of the screw conveyor. Thus, the performance is calculated for a 1-sec time frame in an unsteady computation manner. This methodology will help designers in developing design concepts to improve the dispensation and also at the effective area within a quick turnaround time frame. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DDPM-KTGF" title="DDPM-KTGF">DDPM-KTGF</a>, <a href="https://publications.waset.org/abstracts/search?q=gas-solids%20multiphase%20flow" title=" gas-solids multiphase flow"> gas-solids multiphase flow</a>, <a href="https://publications.waset.org/abstracts/search?q=screw%20conveyor" title=" screw conveyor"> screw conveyor</a>, <a href="https://publications.waset.org/abstracts/search?q=Unsteady" title=" Unsteady"> Unsteady</a> </p> <a href="https://publications.waset.org/abstracts/139049/computational-fluid-dynamics-cfd-simulation-approach-for-developing-new-powder-dispensing-device" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/139049.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18155</span> CFD Simulation Approach for Developing New Powder Dispensing Device</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Revanth%20Rallapalli">Revanth Rallapalli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Manually dispensing powders can be difficult as it requires gradually pouring and checking the amount on the scale to be dispensed. Current systems are manual and non-continuous in nature and are user-dependent and difficult to control powder dispensation. Recurrent dosing of powdered medicines in precise amounts quickly and accurately has been an all-time challenge. Various new powder dispensing mechanisms are being designed to overcome these challenges. A battery-operated screw conveyor mechanism is being innovated to overcome the above problems faced. These inventions are numerically evaluated at the concept development level by employing Computational Fluid Dynamics (CFD) of gas-solids multiphase flow systems. CFD has been very helpful in the development of such devices saving time and money by reducing the number of prototypes and testing. This paper describes a simulation of powder dispensation from the trocar’s end by considering the powder as secondary flow in the air, is simulated by using the technique called Dense Discrete Phase Model incorporated with Kinetic Theory of Granular Flow (DDPM-KTGF). By considering the volume fraction of powder as 50%, the transportation of powder from the inlet side to the trocar’s end side is done by rotation of the screw conveyor. The performance is calculated for a 1-sec time frame in an unsteady computation manner. This methodology will help designers in developing design concepts to improve the dispensation and the effective area within a quick turnaround time frame. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=multiphase%20flow" title="multiphase flow">multiphase flow</a>, <a href="https://publications.waset.org/abstracts/search?q=screw%20conveyor" title=" screw conveyor"> screw conveyor</a>, <a href="https://publications.waset.org/abstracts/search?q=transient" title=" transient"> transient</a>, <a href="https://publications.waset.org/abstracts/search?q=dense%20discrete%20phase%20model%20%28DDPM%29" title=" dense discrete phase model (DDPM)"> dense discrete phase model (DDPM)</a>, <a href="https://publications.waset.org/abstracts/search?q=kinetic%20theory%20of%20granular%20flow%20%28KTGF%29" title=" kinetic theory of granular flow (KTGF)"> kinetic theory of granular flow (KTGF)</a> </p> <a href="https://publications.waset.org/abstracts/143190/cfd-simulation-approach-for-developing-new-powder-dispensing-device" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143190.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">146</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18154</span> Mergers and Acquisitions in the Banking Sector: The West African Experience</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sunday%20Odunaiya">Sunday Odunaiya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The statistics of banks in operation in this current dispensation compared to some decades ago has brought about a lot of changes on the face of the financial system. The demand of customers, technological advancement, and government policies among others has therefore generated a lot of heat for financial sector’s growth, sustenance and survival. This paper discusses mergers and acquisitions (M&A) in banking sector using West Africa as a yardstick of evaluation. It explains rigorously the conditions that warrant mergers and acquisitions in the banking sector, its effect, and how to ensure mergers and acquisitions effectiveness in the banking sector. The conceptual and empirical review of the relevant literature were done systematically while value-increasing and value-decreasing theories were used to substantiate the discourse. Findings of this paper show that mergers and acquisitions is a practical and conscious activity in Nigeria, Ghana and Ivory Coast from earliest time till date with tremendous turnaround in the financial sector. It was found out that M&A is consensually arrived at by the targets and the acquirer on a value-based account. In other words, merger and acquisition is a deliberate decision reached by the management of such bank for a ‘just cause’. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acquisitions" title="acquisitions">acquisitions</a>, <a href="https://publications.waset.org/abstracts/search?q=merger" title=" merger"> merger</a>, <a href="https://publications.waset.org/abstracts/search?q=management" title=" management"> management</a>, <a href="https://publications.waset.org/abstracts/search?q=financial%20sector" title=" financial sector"> financial sector</a> </p> <a href="https://publications.waset.org/abstracts/92440/mergers-and-acquisitions-in-the-banking-sector-the-west-african-experience" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/92440.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">276</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18153</span> A Case Study of Clinicians’ Perceptions of Enterprise Content Management at Tygerberg Hospital</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Temitope%20O.%20Tokosi">Temitope O. Tokosi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Healthcare is a human right. The sensitivity of health issues has necessitated the introduction of Enterprise Content Management (ECM) at district hospitals in the Western Cape Province of South Africa. The objective is understanding clinicians&rsquo; perception of ECM at their workplace. It is a descriptive case study design of constructivist paradigm. It employed a phenomenological data analysis method using a pattern matching deductive based analytical procedure. Purposive and s4nowball sampling techniques were applied in selecting participants. Clinicians expressed concerns and frustrations using ECM such as, non-integration with other hospital systems. Inadequate access points to ECM. Incorrect labelling of notes and bar-coding causes more time wasted in finding information. System features and/or functions (such as search and edit) are not possible. Hospital management and clinicians are not constantly interacting and discussing. Information turnaround time is unacceptably lengthy. Resolving these problems would involve a positive working relationship between hospital management and clinicians. In addition, prioritising the problems faced by clinicians in relation to relevance can ensure problem-solving in order to meet clinicians&rsquo; expectations and hospitals&rsquo; objective. Clinicians&rsquo; perception should invoke attention from hospital management with regards technology use. The study&rsquo;s results can be generalised across clinician groupings exposed to ECM at various district hospitals because of professional and hospital homogeneity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clinician" title="clinician">clinician</a>, <a href="https://publications.waset.org/abstracts/search?q=electronic%20content%20management" title=" electronic content management"> electronic content management</a>, <a href="https://publications.waset.org/abstracts/search?q=hospital" title=" hospital"> hospital</a>, <a href="https://publications.waset.org/abstracts/search?q=perception" title=" perception"> perception</a>, <a href="https://publications.waset.org/abstracts/search?q=technology" title=" technology"> technology</a> </p> <a href="https://publications.waset.org/abstracts/70508/a-case-study-of-clinicians-perceptions-of-enterprise-content-management-at-tygerberg-hospital" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70508.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">233</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18152</span> Integrating Distributed Architectures in Highly Modular Reinforcement Learning Libraries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Albert%20Bou">Albert Bou</a>, <a href="https://publications.waset.org/abstracts/search?q=Sebastian%20Dittert"> Sebastian Dittert</a>, <a href="https://publications.waset.org/abstracts/search?q=Gianni%20de%20Fabritiis"> Gianni de Fabritiis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Advancing reinforcement learning (RL) requires tools that are flexible enough to easily prototype new methods while avoiding impractically slow experimental turnaround times. To match the first requirement, the most popular RL libraries advocate for highly modular agent composability, which facilitates experimentation and development. To solve challenging environments within reasonable time frames, scaling RL to large sampling and computing resources has proved a successful strategy. However, this capability has been so far difficult to combine with modularity. In this work, we explore design choices to allow agent composability both at a local and distributed level of execution. We propose a versatile approach that allows the definition of RL agents at different scales through independent, reusable components. We demonstrate experimentally that our design choices allow us to reproduce classical benchmarks, explore multiple distributed architectures, and solve novel and complex environments while giving full control to the user in the agent definition and training scheme definition. We believe this work can provide useful insights to the next generation of RL libraries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=deep%20reinforcement%20learning" title="deep reinforcement learning">deep reinforcement learning</a>, <a href="https://publications.waset.org/abstracts/search?q=Python" title=" Python"> Python</a>, <a href="https://publications.waset.org/abstracts/search?q=PyTorch" title=" PyTorch"> PyTorch</a>, <a href="https://publications.waset.org/abstracts/search?q=distributed%20training" title=" distributed training"> distributed training</a>, <a href="https://publications.waset.org/abstracts/search?q=modularity" title=" modularity"> modularity</a>, <a href="https://publications.waset.org/abstracts/search?q=library" title=" library"> library</a> </p> <a href="https://publications.waset.org/abstracts/167759/integrating-distributed-architectures-in-highly-modular-reinforcement-learning-libraries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167759.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">83</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18151</span> The Use of SD Bioline TB AgMPT64® Detection Assay for Rapid Characterization of Mycobacteria in Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Ibrahim">S. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=U.%20B.%20Abubakar"> U. B. Abubakar</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Danbirni"> S. Danbirni</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Usman"> A. Usman</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20M.%20Ballah"> F. M. Ballah</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20A.%20Kudi"> C. A. Kudi</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Lawson"> L. Lawson</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20H.%20Abdulrazak"> G. H. Abdulrazak</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20A.%20Abdulkadir"> I. A. Abdulkadir</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Performing culture and characterization of mycobacteria in low resource settings like Nigeria is a very difficult task to undertake because of the very few and limited laboratories carrying out such an experiment; this is a largely due to stringent and laborious nature of the tests. Hence, a rapid, simple and accurate test for characterization is needed. The &ldquo;SD BIOLINE TB Ag MPT 64 Rapid &reg;&rdquo; is a simple and rapid immunochromatographic test used in differentiating Mycobacteria into <em>Mycobacterium tuberculosis</em> (NTM). The 100 sputa were obtained from patients suspected to be infected with tuberculosis and presented themselves to hospitals for check-up and treatment were involved in the study. The samples were cultured in a class III Biosafety cabinet and level III biosafety practices were followed. Forty isolates were obtained from the cultured sputa, and there were identified as Acid-fast bacilli (AFB) using Zeihl-Neelsen acid-fast stain. All the isolates (AFB positive) were then subjected to the SD BIOLINE Analyses. A total of 31 (77.5%) were characterized as MTBC, while nine (22.5%) were NTM. The total turnaround time for the rapid assay was just 30 minutes as compared to a few days of phenotypic and genotypic method. It was simple, rapid and reliable test to differentiate MTBC from NTM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=culture" title="culture">culture</a>, <a href="https://publications.waset.org/abstracts/search?q=mycobacteria" title=" mycobacteria"> mycobacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=non%20tuberculous%20mycobacterium" title=" non tuberculous mycobacterium"> non tuberculous mycobacterium</a>, <a href="https://publications.waset.org/abstracts/search?q=SD%20Bioline" title=" SD Bioline"> SD Bioline</a> </p> <a href="https://publications.waset.org/abstracts/55091/the-use-of-sd-bioline-tb-agmpt64-detection-assay-for-rapid-characterization-of-mycobacteria-in-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55091.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">345</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18150</span> Analysis of the Annual Proficiency Testing Procedure for Intermediate Reference Laboratories Conducted by the National Reference Laboratory from 2013 to 2017</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Reena%20K.">Reena K.</a>, <a href="https://publications.waset.org/abstracts/search?q=Mamatha%20H.%20G."> Mamatha H. G.</a>, <a href="https://publications.waset.org/abstracts/search?q=Somshekarayya"> Somshekarayya</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Kumar"> P. Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The annual proficiency testing of intermediate reference laboratories is conducted by the National Reference Laboratory (NRL) to assess the efficiency of the laboratories to correctly identify Mycobacterium tuberculosis and to determine its drug susceptibility pattern. The proficiency testing results from 2013 to 2017 were analyzed to determine laboratories that were consistent in reporting quality results and those that had difficulty in doing so. Methods: A panel of twenty cultures were sent out to each of these laboratories. The laboratories were expected to grow the cultures in their own laboratories, set up drug susceptibly testing by all the methods they were certified for and report the results within the stipulated time period. The turnaround time for reporting results, specificity, sensitivity positive and negative predictive values and efficiency of the laboratory in identifying the cultures were analyzed. Results: Most of the laboratories had reported their results within the stipulated time period. However, there was enormous delay in reporting results from few of the laboratories. This was mainly due to improper functioning of the biosafety level III laboratory. Only 40% of the laboratories had 100% efficiency in solid culture using Lowenstein Jensen medium. This was expected as a solid culture, and drug susceptibility testing is not used for diagnosing drug resistance. Rapid molecular methods such as Line probe assay and Genexpert are used to determine drug resistance. Automated liquid culture system such as the Mycobacterial growth indicator tube is used to determine prognosis of the patient while on treatment. It was observed that 90% of the laboratories had achieved 100% in the liquid culture method. Almost all laboratories had achieved 100% efficiency in the line probe assay method which is the method of choice for determining drug-resistant tuberculosis. Conclusion: Since the liquid culture and line probe assay technologies are routinely used for the detection of drug-resistant tuberculosis the laboratories exhibited higher level of efficiency as compared to solid culture and drug susceptibility testing which are rarely used. The infrastructure of the laboratory should be maintained properly so that samples can be processed safely and results could be declared on time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=annual%20proficiency%20testing" title="annual proficiency testing">annual proficiency testing</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20susceptibility%20testing" title=" drug susceptibility testing"> drug susceptibility testing</a>, <a href="https://publications.waset.org/abstracts/search?q=intermediate%20reference%20laboratory" title=" intermediate reference laboratory"> intermediate reference laboratory</a>, <a href="https://publications.waset.org/abstracts/search?q=national%20reference%20laboratory" title=" national reference laboratory"> national reference laboratory</a> </p> <a href="https://publications.waset.org/abstracts/82990/analysis-of-the-annual-proficiency-testing-procedure-for-intermediate-reference-laboratories-conducted-by-the-national-reference-laboratory-from-2013-to-2017" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82990.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">182</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18149</span> Challenges in Achieving Profitability for MRO Companies in the Aviation Industry: An Analytical Approach</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nur%20Sahver%20Uslu">Nur Sahver Uslu</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%CC%87%20Hakan%20B%C3%BCy%C3%BCkl%C3%BC"> Ali̇ Hakan Büyüklü</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Maintenance, Repair, and Overhaul (MRO) costs are significant in the aviation industry. On the other hand, companies that provide MRO services to the aviation industry but are not dominant in the sector, need to determine the right strategies for sustainable profitability in a competitive environment. This study examined the operational real data of a small medium enterprise (SME) MRO company where analytical methods are not widely applied. The company's customers were divided into two categories: airline companies and non-airline companies, and the variables that best explained profitability were analyzed with Logistic Regression for each category and the results were compared. First, data reduction was applied to the transformed variables that went through the data cleaning and preparation stages, and the variables to be included in the model were decided. The misclassification rates for the logistic regression results concerning both customer categories are similar, indicating consistent model performance across different segments. Less profit margin is obtained from airline customers, which can be explained by the variables part description, time to quotation (TTQ), turnaround time (TAT), manager, part cost, and labour cost. The higher profit margin obtained from non-airline customers is explained only by the variables part description, part cost, and labour cost. Based on the two models, it can be stated that it is significantly more challenging for the MRO company, which is the subject of our study, to achieve profitability from Airline customers. While operational processes and organizational structure also affect the profit from airline customers, only the type of parts and costs determine the profit for non-airlines. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aircraft" title="aircraft">aircraft</a>, <a href="https://publications.waset.org/abstracts/search?q=aircraft%20components" title=" aircraft components"> aircraft components</a>, <a href="https://publications.waset.org/abstracts/search?q=aviation" title=" aviation"> aviation</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20analytics" title=" data analytics"> data analytics</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20science" title=" data science"> data science</a>, <a href="https://publications.waset.org/abstracts/search?q=gini%20index" title=" gini index"> gini index</a>, <a href="https://publications.waset.org/abstracts/search?q=maintenance" title=" maintenance"> maintenance</a>, <a href="https://publications.waset.org/abstracts/search?q=repair" title=" repair"> repair</a>, <a href="https://publications.waset.org/abstracts/search?q=and%20overhaul" title=" and overhaul"> and overhaul</a>, <a href="https://publications.waset.org/abstracts/search?q=MRO" title=" MRO"> MRO</a>, <a href="https://publications.waset.org/abstracts/search?q=logistic%20regression" title=" logistic regression"> logistic regression</a>, <a href="https://publications.waset.org/abstracts/search?q=profit" title=" profit"> profit</a>, <a href="https://publications.waset.org/abstracts/search?q=variable%20clustering" title=" variable clustering"> variable clustering</a>, <a href="https://publications.waset.org/abstracts/search?q=variable%20reduction" title=" variable reduction"> variable reduction</a> </p> <a href="https://publications.waset.org/abstracts/188467/challenges-in-achieving-profitability-for-mro-companies-in-the-aviation-industry-an-analytical-approach" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188467.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">33</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18148</span> Compare Hot Forming and Cold Forming in Rolling Process</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ali%20Moarrefzadeh">Ali Moarrefzadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In metalworking, rolling is a metal forming process in which metal stock is passed through a pair of rolls. Rolling is classified according to the temperature of the metal rolled. If the temperature of the metal is above its recrystallization temperature, then the process is termed as hot rolling. If the temperature of the metal is below its recrystallization temperature, the process is termed as cold rolling. In terms of usage, hot rolling processes more tonnage than any other manufacturing process, and cold rolling processes the most tonnage out of all cold working processes. This article describes the use of advanced tubing inspection NDT methods for boiler and heat exchanger equipment in the petrochemical industry to supplement major turnaround inspections. The methods presented include remote field eddy current, magnetic flux leakage, internal rotary inspection system and eddy current. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hot%20forming" title="hot forming">hot forming</a>, <a href="https://publications.waset.org/abstracts/search?q=cold%20forming" title=" cold forming"> cold forming</a>, <a href="https://publications.waset.org/abstracts/search?q=metal" title=" metal"> metal</a>, <a href="https://publications.waset.org/abstracts/search?q=rolling" title=" rolling"> rolling</a>, <a href="https://publications.waset.org/abstracts/search?q=simulation" title=" simulation "> simulation </a> </p> <a href="https://publications.waset.org/abstracts/11373/compare-hot-forming-and-cold-forming-in-rolling-process" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11373.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">529</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18147</span> Integrating a Universal Forensic DNA Database: Anticipated Deterrent Effects</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Karen%20Fang">Karen Fang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Investigative genetic genealogy has attracted much interest in both the field of ethics and the public eye due to its global application in criminal cases. Arguments have been made regarding privacy and informed consent, especially with law enforcement using consumer genetic testing results to convict individuals. In the case of public interest, DNA databases have the strong potential to significantly reduce crime, which in turn leads to safer communities and better futures. With the advancement of genetic technologies, the integration of a universal forensic DNA database in violent crimes, crimes against children, and missing person cases is expected to deter crime while protecting one’s privacy. Rather than collecting whole genomes from the whole population, STR profiles can be used to identify unrelated individuals without compromising personal information such as physical appearance, disease risk, and geographical origin, and additionally, reduce cost and storage space. STR DNA profiling is already used in the forensic science field and going a step further benefits several areas, including the reduction in recidivism, improved criminal court case turnaround time, and just punishment. Furthermore, adding individuals to the database as early as possible prevents young offenders and first-time offenders from participating in criminal activity. It is important to highlight that DNA databases should be inclusive and tightly governed, and the misconception on the use of DNA based on crime television series and other media sources should be addressed. Nonetheless, deterrent effects have been observed in countries like the US and Denmark with DNA databases that consist of serious violent offenders. Fewer crimes were reported, and fewer people were convicted of those crimes- a favorable outcome, not even the death penalty could provide. Currently, there is no better alternative than a universal forensic DNA database made up of STR profiles. It can open doors for investigative genetic genealogy and fostering better communities. Expanding the appropriate use of DNA databases is ethically acceptable and positively impacts the public. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioethics" title="bioethics">bioethics</a>, <a href="https://publications.waset.org/abstracts/search?q=deterrent%20effects" title=" deterrent effects"> deterrent effects</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20database" title=" DNA database"> DNA database</a>, <a href="https://publications.waset.org/abstracts/search?q=investigative%20genetic%20genealogy" title=" investigative genetic genealogy"> investigative genetic genealogy</a>, <a href="https://publications.waset.org/abstracts/search?q=privacy" title=" privacy"> privacy</a>, <a href="https://publications.waset.org/abstracts/search?q=public%20interest" title=" public interest"> public interest</a> </p> <a href="https://publications.waset.org/abstracts/143388/integrating-a-universal-forensic-dna-database-anticipated-deterrent-effects" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143388.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">149</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18146</span> Eliminating Injury in the Work Place and Realizing Vision Zero Using Accident Investigation and Analysis as Method: A Case Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ramesh%20Kumar%20Behera">Ramesh Kumar Behera</a>, <a href="https://publications.waset.org/abstracts/search?q=Md.%20Izhar%20Hassan"> Md. Izhar Hassan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Accident investigation and analysis are useful to identify deficiencies in plant, process, and management practices and formulate preventive strategies for injury elimination. In India and other parts of the world, industrial accidents are investigated to know the causes and also to fulfill legal compliances. However, findings of investigation are seldom used appropriately to strengthen Occupational Safety and Health (OSH) in expected lines. The mineral rich state of Odisha in eastern coast of India; known as a hub for Iron and Steel industries, witnessed frequent accidents during 2005-2009. This article based on study of 982 fatal ‘factory-accidents’ occurred in Odisha during the period 2001-2016, discusses the ‘turnaround-story’ resulting in reduction of fatal accident from 122 in 2009 to 45 in 2016. This paper examines various factors causing incidents; accident pattern in steel and chemical sector; role of climate and harsh weather conditions on accident causation. Software such as R, SQL, MS-Excel and Tableau were used for analysis of data. It is found that maximum fatality is caused due to ‘fall from height’ (24%); steel industries are relatively more accident prone; harsh weather conditions of summer increase chances of accident by 20%. Further, the study suggests that enforcement of partial work-restriction around lunch time during peak summer, screening and training of employees reduce accidents due to fall from height. The study indicates that learning from accident investigation and analysis can be used as a method to reduce work related accidents in the journey towards ‘Vision Zero’. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=accident%20investigation%20and%20analysis" title="accident investigation and analysis">accident investigation and analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=fatal%20accidents%20in%20India" title=" fatal accidents in India"> fatal accidents in India</a>, <a href="https://publications.waset.org/abstracts/search?q=fall%20from%20height" title=" fall from height"> fall from height</a>, <a href="https://publications.waset.org/abstracts/search?q=vision%20zero" title=" vision zero"> vision zero</a> </p> <a href="https://publications.waset.org/abstracts/96134/eliminating-injury-in-the-work-place-and-realizing-vision-zero-using-accident-investigation-and-analysis-as-method-a-case-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96134.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18145</span> Execution Time Optimization of Workflow Network with Activity Lead-Time</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Xiaoping%20Qiu">Xiaoping Qiu</a>, <a href="https://publications.waset.org/abstracts/search?q=Binci%20You"> Binci You</a>, <a href="https://publications.waset.org/abstracts/search?q=Yue%20Hu"> Yue Hu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The executive time of the workflow network has an important effect on the efficiency of the business process. In this paper, the activity executive time is divided into the service time and the waiting time, then the lead time can be extracted from the waiting time. The executive time formulas of the three basic structures in the workflow network are deduced based on the activity lead time. Taken the process of e-commerce logistics as an example, insert appropriate lead time for key activities by using Petri net, and the executive time optimization model is built to minimize the waiting time with the time-cost constraints. Then the solution program-using VC++6.0 is compiled to get the optimal solution, which reduces the waiting time of key activities in the workflow, and verifies the role of lead time in the timeliness of e-commerce logistics. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electronic%20business" title="electronic business">electronic business</a>, <a href="https://publications.waset.org/abstracts/search?q=execution%20time" title=" execution time"> execution time</a>, <a href="https://publications.waset.org/abstracts/search?q=lead%20time" title=" lead time"> lead time</a>, <a href="https://publications.waset.org/abstracts/search?q=optimization%20model" title=" optimization model"> optimization model</a>, <a href="https://publications.waset.org/abstracts/search?q=petri%20net" title=" petri net"> petri net</a>, <a href="https://publications.waset.org/abstracts/search?q=time%20workflow%20network" title=" time workflow network"> time workflow network</a> </p> <a href="https://publications.waset.org/abstracts/137019/execution-time-optimization-of-workflow-network-with-activity-lead-time" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137019.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">176</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18144</span> The Diagnostic Utility and Sensitivity of the Xpert® MTB/RIF Assay in Diagnosing Mycobacterium tuberculosis in Bone Marrow Aspirate Specimens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nadhiya%20N.%20Subramony">Nadhiya N. Subramony</a>, <a href="https://publications.waset.org/abstracts/search?q=Jenifer%20Vaughan"> Jenifer Vaughan</a>, <a href="https://publications.waset.org/abstracts/search?q=Lesley%20E.%20Scott"> Lesley E. Scott</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In South Africa, the World Health Organisation estimated 454000 new cases of Mycobacterium tuberculosis (M.tb) infection (MTB) in 2015. Disseminated tuberculosis arises from the haematogenous spread and seeding of the bacilli in extrapulmonary sites. The gold standard for the detection of MTB in bone marrow is TB culture which has an average turnaround time of 6 weeks. Histological examinations of trephine biopsies to diagnose MTB also have a time delay owing mainly to the 5-7 day processing period prior to microscopic examination. Adding to the diagnostic delay is the non-specific nature of granulomatous inflammation which is the hallmark of MTB involvement of the bone marrow. A Ziehl-Neelson stain (which highlights acid-fast bacilli) is therefore mandatory to confirm the diagnosis but can take up to 3 days for processing and evaluation. Owing to this delay in diagnosis, many patients are lost to follow up or remain untreated whilst results are awaited, thus encouraging the spread of undiagnosed TB. The Xpert® MTB/RIF (Cepheid, Sunnyvale, CA) is the molecular test used in the South African national TB program as the initial diagnostic test for pulmonary TB. This study investigates the optimisation and performance of the Xpert® MTB/RIF on bone marrow aspirate specimens (BMA), a first since the introduction of the assay in the diagnosis of extrapulmonary TB. BMA received for immunophenotypic analysis as part of the investigation into disseminated MTB or in the evaluation of cytopenias in immunocompromised patients were used. Processing BMA on the Xpert® MTB/RIF was optimised to ensure bone marrow in EDTA and heparin did not inhibit the PCR reaction. Inactivated M.tb was spiked into the clinical bone marrow specimen and distilled water (as a control). A volume of 500mcl and an incubation time of 15 minutes with sample reagent were investigated as the processing protocol. A total of 135 BMA specimens had sufficient residual volume for Xpert® MTB/RIF testing however 22 specimens (16.3%) were not included in the final statistical analysis as an adequate trephine biopsy and/or TB culture was not available. Xpert® MTB/RIF testing was not affected by BMA material in the presence of heparin or EDTA, but the overall detection of MTB in BMA was low compared to histology and culture. Sensitivity of the Xpert® MTB/RIF compared to both histology and culture was 8.7% (95% confidence interval (CI): 1.07-28.04%) and sensitivity compared to histology only was 11.1% (95% CI: 1.38-34.7%). Specificity of the Xpert® MTB/RIF was 98.9% (95% CI: 93.9-99.7%). Although the Xpert® MTB/RIF generates a faster result than histology and TB culture and is less expensive than culture and drug susceptibility testing, the low sensitivity of the Xpert® MTB/RIF precludes its use for the diagnosis of MTB in bone marrow aspirate specimens and warrants alternative/additional testing to optimise the assay. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20marrow%20aspirate" title="bone marrow aspirate ">bone marrow aspirate </a>, <a href="https://publications.waset.org/abstracts/search?q=extrapulmonary%20TB" title=" extrapulmonary TB"> extrapulmonary TB</a>, <a href="https://publications.waset.org/abstracts/search?q=low%20sensitivity" title=" low sensitivity"> low sensitivity</a>, <a href="https://publications.waset.org/abstracts/search?q=Xpert%C2%AE%20MTB%2FRIF" title=" Xpert® MTB/RIF"> Xpert® MTB/RIF</a> </p> <a href="https://publications.waset.org/abstracts/82583/the-diagnostic-utility-and-sensitivity-of-the-xpert-mtbrif-assay-in-diagnosing-mycobacterium-tuberculosis-in-bone-marrow-aspirate-specimens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82583.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">172</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18143</span> Fast Prototyping of Precise, Flexible, Multiplexed, Printed Electrochemical Enzyme-Linked Immunosorbent Assay System for Point-of-Care Biomarker Quantification</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zahrasadat%20Hosseini">Zahrasadat Hosseini</a>, <a href="https://publications.waset.org/abstracts/search?q=Jie%20Yuan"> Jie Yuan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Point-of-care (POC) diagnostic devices based on lab-on-a-chip (LOC) technology have the potential to revolutionize medical diagnostics. However, the development of an ideal microfluidic system based on LOC technology for diagnostics purposes requires overcoming several obstacles, such as improving sensitivity, selectivity, portability, cost-effectiveness, and prototyping methods. While numerous studies have introduced technologies and systems that advance these criteria, existing systems still have limitations. Electrochemical enzyme-linked immunosorbent assay (e-ELISA) in a LOC device offers numerous advantages, including enhanced sensitivity, decreased turnaround time, minimized sample and analyte consumption, reduced cost, disposability, and suitability for miniaturization, integration, and multiplexing. In this study, we present a novel design and fabrication method for a microfluidic diagnostic platform that integrates screen-printed electrochemical carbon/silver chloride electrodes on flexible printed circuit boards with flexible, multilayer, polydimethylsiloxane (PDMS) microfluidic networks to accurately manipulate and pre-immobilize analytes for performing electrochemical enzyme-linked immunosorbent assay (e-ELISA) for multiplexed quantification of blood serum biomarkers. We further demonstrate fast, cost-effective prototyping, as well as accurate and reliable detection performance of this device for quantification of interleukin-6-spiked samples through electrochemical analytics methods. We anticipate that our invention represents a significant step towards the development of user-friendly, portable, medical-grade, POC diagnostic devices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lab-on-a-chip" title="lab-on-a-chip">lab-on-a-chip</a>, <a href="https://publications.waset.org/abstracts/search?q=point-of-care%20diagnostics" title=" point-of-care diagnostics"> point-of-care diagnostics</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20ELISA" title=" electrochemical ELISA"> electrochemical ELISA</a>, <a href="https://publications.waset.org/abstracts/search?q=biomarker%20quantification" title=" biomarker quantification"> biomarker quantification</a>, <a href="https://publications.waset.org/abstracts/search?q=fast%20prototyping" title=" fast prototyping"> fast prototyping</a> </p> <a href="https://publications.waset.org/abstracts/169509/fast-prototyping-of-precise-flexible-multiplexed-printed-electrochemical-enzyme-linked-immunosorbent-assay-system-for-point-of-care-biomarker-quantification" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169509.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">83</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18142</span> Fast Prototyping of Precise, Flexible, Multiplexed, Printed Electrochemical Enzyme-Linked Immunosorbent Assay Platform for Point-of-Care Biomarker Quantification</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zahrasadat%20Hosseini">Zahrasadat Hosseini</a>, <a href="https://publications.waset.org/abstracts/search?q=Jie%20Yuan"> Jie Yuan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Point-of-care (POC) diagnostic devices based on lab-on-a-chip (LOC) technology have the potential to revolutionize medical diagnostics. However, the development of an ideal microfluidic system based on LOC technology for diagnostics purposes requires overcoming several obstacles, such as improving sensitivity, selectivity, portability, cost-effectiveness, and prototyping methods. While numerous studies have introduced technologies and systems that advance these criteria, existing systems still have limitations. Electrochemical enzyme-linked immunosorbent assay (e-ELISA) in a LOC device offers numerous advantages, including enhanced sensitivity, decreased turnaround time, minimized sample and analyte consumption, reduced cost, disposability, and suitability for miniaturization, integration, and multiplexing. In this study, we present a novel design and fabrication method for a microfluidic diagnostic platform that integrates screen-printed electrochemical carbon/silver chloride electrodes on flexible printed circuit boards with flexible, multilayer, polydimethylsiloxane (PDMS) microfluidic networks to accurately manipulate and pre-immobilize analytes for performing electrochemical enzyme-linked immunosorbent assay (e-ELISA) for multiplexed quantification of blood serum biomarkers. We further demonstrate fast, cost-effective prototyping, as well as accurate and reliable detection performance of this device for quantification of interleukin-6-spiked samples through electrochemical analytics methods. We anticipate that our invention represents a significant step towards the development of user-friendly, portable, medical-grade POC diagnostic devices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lab-on-a-chip" title="lab-on-a-chip">lab-on-a-chip</a>, <a href="https://publications.waset.org/abstracts/search?q=point-of-care%20diagnostics" title=" point-of-care diagnostics"> point-of-care diagnostics</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20ELISA" title=" electrochemical ELISA"> electrochemical ELISA</a>, <a href="https://publications.waset.org/abstracts/search?q=biomarker%20quantification" title=" biomarker quantification"> biomarker quantification</a>, <a href="https://publications.waset.org/abstracts/search?q=fast%20prototyping" title=" fast prototyping"> fast prototyping</a> </p> <a href="https://publications.waset.org/abstracts/169508/fast-prototyping-of-precise-flexible-multiplexed-printed-electrochemical-enzyme-linked-immunosorbent-assay-platform-for-point-of-care-biomarker-quantification" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169508.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">85</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18141</span> The Urgency of Berth Deepening at the Port of Durban </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rowen%20Naicker">Rowen Naicker</a>, <a href="https://publications.waset.org/abstracts/search?q=Dhiren%20Allopi"> Dhiren Allopi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> One of the major problems the Port of Durban is experiencing is addressing shallow spots aggravated by megaships that berth. In the recent years, the vessels that call at the Port have increased in size which calls for draughts that are much deeper. For this reason, these larger vessels can only berth under high tide to avoid the risk of running aground. In addition to this, the ships cannot sail in fully laden which does not make it feasible for ship owners. Further during the berthing materials are displaced from the seabed which result in shallow spots being developed. The permitted draft (under-keel allowance) for the Durban Container Terminal (DCT) is currently 12.2 m. Transnet National Ports Authority (TNPA) are currently investing in a dredging fleet worth almost two billion rand. One of the highlights of this investment would be the building of grab hopper dredger that would be dedicated to the Port by 2017. TNPA are trying various techniques to dissolve the reduction of draughts by implementing dredging maintenance projects but is this sufficient? The ideal resolution would be the deepening and widening of the berths. Plans for this project is in place, but the implementation process is a matter of urgency. The intention of this project will be to accommodate three big vessels rather than two which in turn will improve the turnaround time in the port. The berthing will then no longer depend on high tide to avoid ships running aground. The aim of this paper is to prove the implementation of deepening and widening of the Port of Durban is a matter of urgency. If the plan to deepen and widen the berths at DCT is delayed it will mean a loss of business for the South African economy. If larger vessels cannot be accommodated in the Port of Durban, it will bypass the busiest container handling facility in the Southern hemisphere. Shipping companies are compelled to use larger ships as opposed to smaller vessels to lower port and fuel costs. A delay in the expansion of DCT could also result in an escalation of costs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DCT" title="DCT">DCT</a>, <a href="https://publications.waset.org/abstracts/search?q=deepening" title=" deepening"> deepening</a>, <a href="https://publications.waset.org/abstracts/search?q=berth" title=" berth"> berth</a>, <a href="https://publications.waset.org/abstracts/search?q=port" title=" port"> port</a> </p> <a href="https://publications.waset.org/abstracts/54171/the-urgency-of-berth-deepening-at-the-port-of-durban" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54171.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">400</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18140</span> Lean and Six Sigma in the Freight Railway Supplier Base in South Africa: Factors Leading to Their Application</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hilda%20Kundai%20Chikwanda">Hilda Kundai Chikwanda</a>, <a href="https://publications.waset.org/abstracts/search?q=Lawrence%20Thabo%20Mokhadi"> Lawrence Thabo Mokhadi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The study aimed to review the factors that lead the freight railway suppliers base in South Africa (SA) to apply the Lean and Six Sigma (L&SS) methodologies. A thorough review of the factors that lead organisations, in the different industries, to implement these methodologies was done. L&SS applications were found to be prominent in the automotive industry. In particular, the railway industry in SA and the region were reviewed in terms of challenges in capturing the freight logistics market and growing market share. Qualitative methods have been used to collect primary data and descriptive statistics was used to calculate, describe, and summarize collected research data. The results show that external factors have a greater influence on the implementation of L&SS. The study drew inferences between freight railway supplier base and the application of Lean and Six Sigma (L&SS) methodologies in the SA context. It identified challenges that leads the SA freight railway to lose market share to road freight users. It further observes and recommends that L&SS methodologies are the ideal strategy required to implement a turnaround in the trajectory of freight railways as a competitive freight transport solution. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=production" title="production">production</a>, <a href="https://publications.waset.org/abstracts/search?q=methodology" title=" methodology"> methodology</a>, <a href="https://publications.waset.org/abstracts/search?q=manufacturing" title=" manufacturing"> manufacturing</a>, <a href="https://publications.waset.org/abstracts/search?q=lean" title=" lean"> lean</a>, <a href="https://publications.waset.org/abstracts/search?q=six%20sigma" title=" six sigma"> six sigma</a> </p> <a href="https://publications.waset.org/abstracts/182206/lean-and-six-sigma-in-the-freight-railway-supplier-base-in-south-africa-factors-leading-to-their-application" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/182206.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">45</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18139</span> Memory, Self, and Time: A Bachelardian Perspective </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michael%20Granado">Michael Granado</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The French philosopher Gaston Bachelard’s philosophy of time is articulated in his two works on the subject, the Intuition of the Instant (1932) and his The Dialectic of Duration (1936). Both works present a systematic methodology predicated upon the assumption that our understanding of time has radically changed as a result of Einstein and subsequently needs to be reimagined. Bachelard makes a major distinction in his discussion of time: 1. Time as it is (physical time), 2. Time as we experience it (phenomenological time). This paper will focus on the second distinction, phenomenological time, and explore the connections between Bachelard’s work and contemporary psychology. Several aspects of Bachelard’s philosophy of time nicely complement our current understanding of memory and self and clarify how the self relates to experienced time. Two points, in particular, stand out; the first is the relative nature of subjective time, and the second is the implications of subjective time in the formation of the narrative self. Bachelard introduces two philosophical concepts to explain these points: rhythmanalysis and reverie. By exploring these concepts, it will become apparent that there is an undeniable link between memory, self, and time. Through the use of narrative self, the individual connects and links memories and time together to form a sense of personal identity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gaston%20Bachelard" title="Gaston Bachelard">Gaston Bachelard</a>, <a href="https://publications.waset.org/abstracts/search?q=memory" title=" memory"> memory</a>, <a href="https://publications.waset.org/abstracts/search?q=self" title=" self"> self</a>, <a href="https://publications.waset.org/abstracts/search?q=time" title=" time "> time </a> </p> <a href="https://publications.waset.org/abstracts/127752/memory-self-and-time-a-bachelardian-perspective" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/127752.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">165</span> </span> </div> </div> <ul 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