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Bahamonde-Olaya</title> <meta name="description" content="Search results for: Estefanía Bahamonde-Olaya"> <meta name="keywords" content="Estefanía Bahamonde-Olaya"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Estefanía Bahamonde-Olaya"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 7</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Estefanía Bahamonde-Olaya</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Actor Training in Social Work Education: A Pilot Study of Theatre Workshops to Enhance Clinical Empathy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amanda%20Coleman">Amanda Coleman</a>, <a href="https://publications.waset.org/abstracts/search?q=Estefan%C3%ADa%20Gonzalez"> Estefanía Gonzalez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Empathy is considered an essential skill for engaging with social work clients. Drawing from developments in medical education, researchers will conduct and evaluate a three-part pilot theatre workshop with master level social work students (n ≈ 30) to evaluate the workshop's ability to enhance empathy among participants. Outcomes will be measured using semi-structured post-intervention interviews with a subset of participants (n ≈ 10) as well post-intervention written reflections and pre-and-post intervention quantitative evaluation of empathy using King and Holosko’s 2011 Empathy Scale for Social Workers. The content of the workshop will differ from traditional role plays, which are common in social work education, in that it will draw from role theory and research on creative empathy to emphasize role reversal with clients. Workshops will be held February and March of 2017 with preliminary findings available by April. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=empathy" title=" empathy"> empathy</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20work" title=" social work"> social work</a>, <a href="https://publications.waset.org/abstracts/search?q=theatre" title=" theatre"> theatre</a> </p> <a href="https://publications.waset.org/abstracts/62121/actor-training-in-social-work-education-a-pilot-study-of-theatre-workshops-to-enhance-clinical-empathy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62121.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">271</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> The Influence of Silica on the Properties of Cementitious Composites </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eva%20Stefanovska">Eva Stefanovska</a>, <a href="https://publications.waset.org/abstracts/search?q=Estefania%20Cuenca"> Estefania Cuenca</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandra%20Momirov"> Aleksandra Momirov</a>, <a href="https://publications.waset.org/abstracts/search?q=Monika%20Fidanchevska"> Monika Fidanchevska</a>, <a href="https://publications.waset.org/abstracts/search?q=Liberato%20Ferrara"> Liberato Ferrara</a>, <a href="https://publications.waset.org/abstracts/search?q=Emilija%20Fidanchevski"> Emilija Fidanchevski</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Silica is used in construction materials as a part of natural raw materials or as an additive in powder form (micro and nano dimensions). SiO₂ particles in cement act as centers of nucleation, as a filler or as pozzolan material. In this regard, silica improves the microstructure of cementitious composites, increases the mechanical properties, and finally also results into improved durability of the final products. Improved properties of cementitious composites may lead to better structural efficiency, which, together with increased durability, results into increased sustainability signature of structures made with this kind of materials. The aim of the present work was to investigate the influence of silica on the properties of cement. Fly ash (as received and mechanically activated) and synthetized silica (sol-gel method using TEOS as precursor) was used in the investigation as source of silica. Four types of cement mixtures were investigated (reference cement paste, cement paste with addition of 15wt.% as-received fly ash, cement paste with 15 wt.% mechanically activated fly ash and cement paste with 14wt.% mechanically activated fly ash and 1 wt.% silica). The influence of silica on setting time and mechanical properties (2, 7 and 28 days) was followed. As a matter of fact it will be shown that cement paste with composition 85 wt. % cement, 14 wt.% mechanically activated fly ash and 1 wt. % SiO₂ obtained by the sol-gel method was the best performing one, with increased compressive and flexure strength by 9 and 10 % respectively, as compared to the reference mixture. Acknowledgements: 'COST Action CA15202, www.sarcos.eng.cam.ac.uk' <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cement" title="cement">cement</a>, <a href="https://publications.waset.org/abstracts/search?q=fly%20ash" title=" fly ash"> fly ash</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20properties" title=" mechanical properties"> mechanical properties</a>, <a href="https://publications.waset.org/abstracts/search?q=silica" title=" silica"> silica</a>, <a href="https://publications.waset.org/abstracts/search?q=sol-gel" title=" sol-gel"> sol-gel</a> </p> <a href="https://publications.waset.org/abstracts/116244/the-influence-of-silica-on-the-properties-of-cementitious-composites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/116244.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">145</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Pilot Program for the Promotion of Normal Childbirth in the North, Northeast and Midwest of Brazil</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nat%C3%A1lia%20Bruno%20Chaves">Natália Bruno Chaves</a>, <a href="https://publications.waset.org/abstracts/search?q=Richardes%20Ca%C3%BAla"> Richardes Caúla</a>, <a href="https://publications.waset.org/abstracts/search?q=Roosevelt%20do%20Vale"> Roosevelt do Vale</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniela%20Toneti"> Daniela Toneti</a>, <a href="https://publications.waset.org/abstracts/search?q=Rafaela%20Carvalho"> Rafaela Carvalho</a>, <a href="https://publications.waset.org/abstracts/search?q=Renata%20Silva%20Lopes"> Renata Silva Lopes</a>, <a href="https://publications.waset.org/abstracts/search?q=Ant%C3%B4nio%20Carlos%20J%C3%BAnior"> Antônio Carlos Júnior</a>, <a href="https://publications.waset.org/abstracts/search?q=Adner%20Nobre"> Adner Nobre</a>, <a href="https://publications.waset.org/abstracts/search?q=Viviane%20Santiago"> Viviane Santiago</a>, <a href="https://publications.waset.org/abstracts/search?q=Yara%20Alana%20Caldato"> Yara Alana Caldato</a>, <a href="https://publications.waset.org/abstracts/search?q=Estefania%20Rodriguez%20Urrego"> Estefania Rodriguez Urrego</a>, <a href="https://publications.waset.org/abstracts/search?q=Andr%C3%A9%20Buarque%20Lemos"> André Buarque Lemos</a>, <a href="https://publications.waset.org/abstracts/search?q=Catarina%20Nucci%20Stetner"> Catarina Nucci Stetner</a>, <a href="https://publications.waset.org/abstracts/search?q=Marcos%20Mauro%20Barreto"> Marcos Mauro Barreto</a>, <a href="https://publications.waset.org/abstracts/search?q=Stefany%20Moreira%20Lima"> Stefany Moreira Lima</a>, <a href="https://publications.waset.org/abstracts/search?q=Mara%20Cavalcante"> Mara Cavalcante</a>, <a href="https://publications.waset.org/abstracts/search?q=Ticiane%20Ribeiro"> Ticiane Ribeiro</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Well Born (Nascer Bem – in Portuguese) Program was created in the Hapvida health network with the aim of improving access to safe and quality prenatal care for users. In addition to offering a line of prenatal care, the inclusion of obstetric nursing and the decentralization of childbirth, bring security that professionals did not indicate the route of delivery for professional convenience. The introduction of the nursing consultation came to reinforce the care to our users, strengthening their bond and reception. In 2021, the program maintained an average of 40% of normal births in the north, northeast and central-west regions of Brazil, an average above that observed in the rest of the country's private health systems, around 20%. In addition, the neonatal hospitalization rate of this population remained around 5.1%, a figure below the national average. With these data, the “Nascer Bem” program is affirmed as a safe and effective strategy for the promotion of safe normal birth. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=quality" title="quality">quality</a>, <a href="https://publications.waset.org/abstracts/search?q=safe" title=" safe"> safe</a>, <a href="https://publications.waset.org/abstracts/search?q=prenatal" title=" prenatal"> prenatal</a>, <a href="https://publications.waset.org/abstracts/search?q=obstetric%20nursing" title=" obstetric nursing"> obstetric nursing</a> </p> <a href="https://publications.waset.org/abstracts/153230/pilot-program-for-the-promotion-of-normal-childbirth-in-the-north-northeast-and-midwest-of-brazil" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/153230.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">119</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Environmental Consequences of Metal Concentrations in Stream Sediments of Atoyac River Basin, Central Mexico: Natural and Industrial Influences</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=V.%20C.%20Shruti">V. C. Shruti</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20F.%20Rodr%C3%ADguez-Espinosa"> P. F. Rodríguez-Espinosa</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20C.%20Escobedo-Ur%C3%ADas"> D. C. Escobedo-Urías</a>, <a href="https://publications.waset.org/abstracts/search?q=Estefan%C3%ADa%20Martinez%20Tavera"> Estefanía Martinez Tavera</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20P.%20Jonathan"> M. P. Jonathan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Atoyac River, a major south-central river flowing through the states of Puebla and Tlaxcala in Mexico is significantly impacted by the natural volcanic inputs in addition with wastewater discharges from urban, agriculture and industrial zones. In the present study, core samples were collected from R. Atoyac and analyzed for sediment granularity, major (Al, Fe, Ca, Mg, K, P and S) and trace elemental concentrations (Ba, Cr, Cd, Mn, Pb, Sr, V, Zn, Zr). The textural studies reveal that the sediments are mostly sand sized particles exceeding 99% and with very few to no presence of mud fractions. It is observed that most of the metals like (avg: all values in μg g<sup>-1</sup>) Ca (35,528), Mg (10,789), K (7453), S (1394), Ba (203), Cr (30), Cd (4), Pb (11), Sr (435), Zn (76) and Zr (88) are enriched throughout the sediments mainly sourced from volcanic inputs, source rock composition of Atoyac River basin and industrial influences from the Puebla city region. Contamination indices, such as anthropogenic factor (AF), enrichment factor (EF) and geoaccumulation index (I<sub>geo</sub>), were used to investigate the level of contamination and toxicity as well as quantitatively assess the influences of human activities on metal concentrations. The AF values (>1) for Ba, Ca, Mg, Na, K, P and S suggested volcanic inputs from the study region, where as Cd and Zn are attributed to the impacts of industrial inputs in this zone. The EF and I<sub>geo</sub> values revealed an extreme enrichment of S and Cd. The ecological risks were evaluated using potential ecological risk index (RI) and the results indicate that the metals Cd and V pose a major hazard for the biological community. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Atoyac%20River" title="Atoyac River">Atoyac River</a>, <a href="https://publications.waset.org/abstracts/search?q=contamination%20indices" title=" contamination indices"> contamination indices</a>, <a href="https://publications.waset.org/abstracts/search?q=metal%20concentrations" title=" metal concentrations"> metal concentrations</a>, <a href="https://publications.waset.org/abstracts/search?q=Mexico" title=" Mexico"> Mexico</a>, <a href="https://publications.waset.org/abstracts/search?q=textural%20studies" title=" textural studies"> textural studies</a> </p> <a href="https://publications.waset.org/abstracts/56024/environmental-consequences-of-metal-concentrations-in-stream-sediments-of-atoyac-river-basin-central-mexico-natural-and-industrial-influences" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56024.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Prevalence of Human Papillomavirus in Squamous Intraepithelial Lesions and Cervical Cancer in Women of the North of Chihuahua, Mexico</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Estefania%20Ponce-Amaya">Estefania Ponce-Amaya</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Lidia%20Arellano-Ortiz"> Ana Lidia Arellano-Ortiz</a>, <a href="https://publications.waset.org/abstracts/search?q=Cecilia%20Diaz-Hernandez"> Cecilia Diaz-Hernandez</a>, <a href="https://publications.waset.org/abstracts/search?q=Jose%20Alberto%20Lopez-Diaz"> Jose Alberto Lopez-Diaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20De%20La%20Mora-Covarrubias"> Antonio De La Mora-Covarrubias</a>, <a href="https://publications.waset.org/abstracts/search?q=Claudia%20Lucia%20Vargas-Requena"> Claudia Lucia Vargas-Requena</a>, <a href="https://publications.waset.org/abstracts/search?q=Mauricio%20Salcedo-Vargas"> Mauricio Salcedo-Vargas</a>, <a href="https://publications.waset.org/abstracts/search?q=Florinda%20Jimenez-Vega"> Florinda Jimenez-Vega </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cervical Cancer (CC) is the second leading cause of death among women worldwide and it had been associated with a persistent infection of human papillomavirus (HPV). The goal of the current study was to identify the prevalence of HPV infection in women with abnormal Pap smear who were attended at Dysplasia Clinic of Ciudad Juarez, Mexico. Methods: Cervical samples from 146 patients, who attended the Colposcopy Clinic at Sanitary Jurisdiction II of Cd Juarez, were collected for histopathology and molecular study. DNA was isolated for the HPV detection by Polymerase Chain Reaction (PCR) using MY09/011 and GP5/6 primers. The associated risk factors were assessed by a questionnaire. The statistical analysis was performed by ANOVA, using EpiINFO V7 software. Results: HPV infection was present in 142 patients (97.3 %). The prevalence of HPV infection was distributed in a 96% of all evaluated groups, low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HISIL) and CC. We found a statistical significance (α = <0.05) between gestation and number of births as risk factors. The median values showed an ascending tend according with the lesion progression. However, CC showed a statistically significant difference with respect to the pre-carcinogenic stages. Conclusions: In these Mexican patients exists a high prevalence of HPV infection, and for that reason, we are studying the most prevalent HPV genotypes in this population. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cervical%20cancer" title="cervical cancer">cervical cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=HPV" title=" HPV"> HPV</a>, <a href="https://publications.waset.org/abstracts/search?q=prevalence%20hpv" title=" prevalence hpv"> prevalence hpv</a>, <a href="https://publications.waset.org/abstracts/search?q=squamous%20intraepithelial%20lesion" title=" squamous intraepithelial lesion"> squamous intraepithelial lesion</a> </p> <a href="https://publications.waset.org/abstracts/79528/prevalence-of-human-papillomavirus-in-squamous-intraepithelial-lesions-and-cervical-cancer-in-women-of-the-north-of-chihuahua-mexico" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79528.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">320</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Characterization of Chest Pain in Patients Consulting to the Emergency Department of a Health Institution High Level of Complexity during 2014-2015, Medellin, Colombia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jorge%20Iv%C3%A1n%20Ba%C3%B1ol-Betancur">Jorge Iván Bañol-Betancur</a>, <a href="https://publications.waset.org/abstracts/search?q=Lina%20Mar%C3%ADa%20Mart%C3%ADnez-S%C3%A1nchez"> Lina María Martínez-Sánchez</a>, <a href="https://publications.waset.org/abstracts/search?q=Mar%C3%ADa%20de%20los%20%C3%81ngeles%20Rodr%C3%ADguez-G%C3%A1zquez"> María de los Ángeles Rodríguez-Gázquez</a>, <a href="https://publications.waset.org/abstracts/search?q=Estefan%C3%ADa%20Bahamonde-Olaya"> Estefanía Bahamonde-Olaya</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Mar%C3%ADa%20Guti%C3%A9rrez-Tamayo"> Ana María Gutiérrez-Tamayo</a>, <a href="https://publications.waset.org/abstracts/search?q=Laura%20Isabel%20Jaramillo-Jaramillo"> Laura Isabel Jaramillo-Jaramillo</a>, <a href="https://publications.waset.org/abstracts/search?q=Camilo%20Ruiz-Mej%C3%ADa"> Camilo Ruiz-Mejía</a>, <a href="https://publications.waset.org/abstracts/search?q=Natalia%20Morales-Quintero"> Natalia Morales-Quintero</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Acute chest pain is a distressing sensation between the diaphragm and the base of the neck and it represents a diagnostic challenge for any physician in the emergency department. Objective: To establish the main clinical and epidemiological characteristics of patients who present with chest pain to the emergency department in a private clinic from the city of Medellin, during 2014-2015. Methods: Cross-sectional retrospective observational study. Population and sample were patients who consulted for chest pain in the emergency department who met the eligibility criteria. The information was analyzed in SPSS program vr.21; qualitative variables were described through relative frequencies, and the quantitative through mean and standard deviation ‬or medians according to their distribution in the study population. Results: A total of 231 patients were evaluated, the mean age was 49.5 ± 19.9 years, 56.7% were females. The most frequent pathological antecedents were hypertension 35.5%, diabetes 10,8%, dyslipidemia 10.4% and coronary disease 5.2%. Regarding pain features, in 40.3% of the patients the pain began abruptly, in 38.2% it had a precordial location, for 20% of the cases physical activity acted as a trigger, and 60.6% was oppressive. Costochondritis was the most common cause of chest pain among patients with an established etiologic diagnosis, representing the 18.2%. Conclusions: Although the clinical features of pain reported coincide with the clinical presentation of an acute coronary syndrome, the most common cause of chest pain in study population was costochondritis instead, indicating that it is a differential diagnostic in the approach of patients with pain acute chest. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acute%20coronary%20syndrome" title="acute coronary syndrome">acute coronary syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=chest%20pain" title=" chest pain"> chest pain</a>, <a href="https://publications.waset.org/abstracts/search?q=epidemiology" title=" epidemiology"> epidemiology</a>, <a href="https://publications.waset.org/abstracts/search?q=osteochondritis" title=" osteochondritis"> osteochondritis</a> </p> <a href="https://publications.waset.org/abstracts/71857/characterization-of-chest-pain-in-patients-consulting-to-the-emergency-department-of-a-health-institution-high-level-of-complexity-during-2014-2015-medellin-colombia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/71857.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">343</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Quercetin Nanoparticles and Their Hypoglycemic Effect in a CD1 Mouse Model with Type 2 Diabetes Induced by Streptozotocin and a High-Fat and High-Sugar Diet</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Adriana%20Garcia-Gurrola">Adriana Garcia-Gurrola</a>, <a href="https://publications.waset.org/abstracts/search?q=Carlos%20Adrian%20Pe%C3%B1a%20Natividad"> Carlos Adrian Peña Natividad</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Laura%20Martinez%20Martinez"> Ana Laura Martinez Martinez</a>, <a href="https://publications.waset.org/abstracts/search?q=Alberto%20Abraham%20Escobar%20Puentes"> Alberto Abraham Escobar Puentes</a>, <a href="https://publications.waset.org/abstracts/search?q=Estefania%20Ochoa%20Ruiz"> Estefania Ochoa Ruiz</a>, <a href="https://publications.waset.org/abstracts/search?q=Aracely%20Serrano%20Medina"> Aracely Serrano Medina</a>, <a href="https://publications.waset.org/abstracts/search?q=Abraham%20Wall%20Medrano"> Abraham Wall Medrano</a>, <a href="https://publications.waset.org/abstracts/search?q=Simon%20Yobanny%20Reyes%20Lopez"> Simon Yobanny Reyes Lopez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by elevated blood glucose levels. Quercetin is a natural flavonoid with a hypoglycemic effect, but reported data are inconsistent due mainly to the structural instability and low solubility of quercetin. Nanoencapsulation is a distinct strategy to overcome the intrinsic limitations of quercetin. Therefore, this work aims to develop a quercetin nano-formulation based on biopolymeric starch nanoparticles to enhance the release and hypoglycemic effect of quercetin in T2DM induced mice model. Starch-quercetin nanoparticles were synthesized using high-intensity ultrasonication, and structural and colloidal properties were determined by FTIR and DLS. For in vivo studies, CD1 male mice (n=25) were divided into five groups (n=5). T2DM was induced using a high-fat and high-sugar diet for 32 weeks and streptozotocin injection. Group 1 consisted of healthy mice fed with a normal diet and water ad libitum; Group 2 were diabetic mice treated with saline solution; Group 3 were diabetic mice treated with glibenclamide; Group 4 were diabetic mice treated with empty nanoparticles; and Group 5 was diabetic mice treated with quercetin nanoparticles. Quercetin nanoparticles had a hydrodynamic size of 232 ± 88.45 nm, a PDI of 0.310 ± 0.04 and a zeta potential of -4 ± 0.85 mV. The encapsulation efficiency of nanoparticles was 58 ± 3.33 %. No significant differences (p = > 0.05) were observed in biochemical parameters (lipids, insulin, and peptide C). Groups 3 and 5 showed a similar hypoglycemic effect, but quercetin nanoparticles showed a longer-lasting effect. Histopathological studies reveal that T2DM mice groups showed degenerated and fatty liver tissue; however, a treated group with quercetin nanoparticles showed liver tissue like that of the healthy mice group. These results demonstrate that quercetin nano-formulations based on starch nanoparticles are effective alternatives with hypoglycemic effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=quercetin" title="quercetin">quercetin</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus%20tipo%202" title=" diabetes mellitus tipo 2"> diabetes mellitus tipo 2</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20vivo%20study" title=" in vivo study"> in vivo study</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/188958/quercetin-nanoparticles-and-their-hypoglycemic-effect-in-a-cd1-mouse-model-with-type-2-diabetes-induced-by-streptozotocin-and-a-high-fat-and-high-sugar-diet" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188958.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">34</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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