CINXE.COM

<!DOCTYPE html> <html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-sticky-header-enabled vector-toc-available" lang="en" dir="ltr"> <head> <meta charset="UTF-8"> <title>Domperidone - Wikipedia</title> <script>(function(){var className="client-js vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-sticky-header-enabled vector-toc-available";var cookie=document.cookie.match(/(?:^|; )enwikimwclientpreferences=([^;]+)/);if(cookie){cookie[1].split('%2C').forEach(function(pref){className=className.replace(new RegExp('(^| )'+pref.replace(/-clientpref-\w+$|[^\w-]+/g,'')+'-clientpref-\\w+( |$)'),'$1'+pref+'$2');});}document.documentElement.className=className;}());RLCONF={"wgBreakFrames":false,"wgSeparatorTransformTable":["",""],"wgDigitTransformTable":["",""],"wgDefaultDateFormat":"dmy","wgMonthNames":["","January","February","March","April","May","June","July","August","September","October","November","December"],"wgRequestId":"b4426861-57d7-466c-9e36-5f12a4397979","wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"Domperidone","wgTitle":"Domperidone","wgCurRevisionId":1277381409,"wgRevisionId":1277381409,"wgArticleId":964888,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":["All articles with dead external links","Articles with dead external links from August 2023","Articles with permanently dead external links","Source attribution","CS1 maint: DOI inactive as of November 2024","Articles with short description","Short description is different from Wikidata","Use dmy dates from June 2024","Drugs with non-standard legal status","ECHA InfoCard ID from Wikidata","Drugboxes which contain changes to watched fields","All articles with unsourced statements","Articles with unsourced statements from March 2022","Antiemetics","Antihypotensive agents","Belgian inventions","Chloroarenes","Dopamine antagonists","HERG blocker","Janssen Pharmaceutica","Motility stimulants","Peripherally selective drugs","Piperidines","Potassium channel blockers","Prolactin releasers","Ureas"],"wgPageViewLanguage":"en","wgPageContentLanguage":"en","wgPageContentModel":"wikitext","wgRelevantPageName":"Domperidone","wgRelevantArticleId":964888,"wgIsProbablyEditable":true,"wgRelevantPageIsProbablyEditable":true,"wgRestrictionEdit":[],"wgRestrictionMove":[],"wgNoticeProject":"wikipedia","wgCiteReferencePreviewsActive":false,"wgFlaggedRevsParams":{"tags":{"status":{"levels":1}}},"wgMediaViewerOnClick":true,"wgMediaViewerEnabledByDefault":true,"wgPopupsFlags":0,"wgVisualEditor":{"pageLanguageCode":"en","pageLanguageDir":"ltr","pageVariantFallbacks":"en"},"wgMFDisplayWikibaseDescriptions":{"search":true,"watchlist":true,"tagline":false,"nearby":true},"wgWMESchemaEditAttemptStepOversample":false,"wgWMEPageLength":70000,"wgEditSubmitButtonLabelPublish":true,"wgULSPosition":"interlanguage","wgULSisCompactLinksEnabled":false,"wgVector2022LanguageInHeader":true,"wgULSisLanguageSelectorEmpty":false,"wgWikibaseItemId":"Q424238","wgCheckUserClientHintsHeadersJsApi":["brands","architecture","bitness","fullVersionList","mobile","model","platform","platformVersion"],"GEHomepageSuggestedEditsEnableTopics":true,"wgGETopicsMatchModeEnabled":false,"wgGEStructuredTaskRejectionReasonTextInputEnabled":false,"wgGELevelingUpEnabledForUser":false}; RLSTATE={"ext.globalCssJs.user.styles":"ready","site.styles":"ready","user.styles":"ready","ext.globalCssJs.user":"ready","user":"ready","user.options":"loading","ext.cite.styles":"ready","skins.vector.search.codex.styles":"ready","skins.vector.styles":"ready","skins.vector.icons":"ready","jquery.makeCollapsible.styles":"ready","ext.wikimediamessages.styles":"ready","ext.visualEditor.desktopArticleTarget.noscript":"ready","ext.uls.interlanguage":"ready","wikibase.client.init":"ready"};RLPAGEMODULES=["ext.cite.ux-enhancements","site","mediawiki.page.ready","jquery.makeCollapsible","mediawiki.toc","skins.vector.js","ext.centralNotice.geoIP","ext.centralNotice.startUp","ext.gadget.ReferenceTooltips","ext.gadget.switcher","ext.urlShortener.toolbar","ext.centralauth.centralautologin","mmv.bootstrap","ext.popups","ext.visualEditor.desktopArticleTarget.init","ext.visualEditor.targetLoader","ext.echo.centralauth","ext.eventLogging","ext.wikimediaEvents","ext.navigationTiming","ext.uls.interface","ext.cx.eventlogging.campaigns","ext.cx.uls.quick.actions","wikibase.client.vector-2022","ext.checkUser.clientHints","ext.growthExperiments.SuggestedEditSession"];</script> <script>(RLQ=window.RLQ||[]).push(function(){mw.loader.impl(function(){return["user.options@12s5i",function($,jQuery,require,module){mw.user.tokens.set({"patrolToken":"+\\","watchToken":"+\\","csrfToken":"+\\"}); }];});});</script> <link rel="stylesheet" href="/w/load.php?lang=en&modules=ext.cite.styles%7Cext.uls.interlanguage%7Cext.visualEditor.desktopArticleTarget.noscript%7Cext.wikimediamessages.styles%7Cjquery.makeCollapsible.styles%7Cskins.vector.icons%2Cstyles%7Cskins.vector.search.codex.styles%7Cwikibase.client.init&only=styles&skin=vector-2022"> <script async="" src="/w/load.php?lang=en&modules=startup&only=scripts&raw=1&skin=vector-2022"></script> <meta name="ResourceLoaderDynamicStyles" content=""> <link rel="stylesheet" href="/w/load.php?lang=en&modules=site.styles&only=styles&skin=vector-2022"> <meta name="generator" content="MediaWiki 1.44.0-wmf.20"> <meta name="referrer" content="origin"> <meta name="referrer" content="origin-when-cross-origin"> <meta name="robots" content="max-image-preview:standard"> <meta name="format-detection" content="telephone=no"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Domperidone-from-xtal-3D-bs-17.png/1200px-Domperidone-from-xtal-3D-bs-17.png"> <meta property="og:image:width" content="1200"> <meta property="og:image:height" content="923"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Domperidone-from-xtal-3D-bs-17.png/800px-Domperidone-from-xtal-3D-bs-17.png"> <meta property="og:image:width" content="800"> <meta property="og:image:height" content="615"> <meta property="og:image" content="https://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Domperidone-from-xtal-3D-bs-17.png/640px-Domperidone-from-xtal-3D-bs-17.png"> <meta property="og:image:width" content="640"> <meta property="og:image:height" content="492"> <meta name="viewport" content="width=1120"> <meta property="og:title" content="Domperidone - Wikipedia"> <meta property="og:type" content="website"> <link rel="preconnect" href="//upload.wikimedia.org"> <link rel="alternate" media="only screen and (max-width: 640px)" href="//en.m.wikipedia.org/wiki/Domperidone"> <link rel="alternate" type="application/x-wiki" title="Edit this page" href="/w/index.php?title=Domperidone&action=edit"> <link rel="apple-touch-icon" href="/static/apple-touch/wikipedia.png"> <link rel="icon" href="/static/favicon/wikipedia.ico"> <link rel="search" type="application/opensearchdescription+xml" href="/w/rest.php/v1/search" title="Wikipedia (en)"> <link rel="EditURI" type="application/rsd+xml" href="//en.wikipedia.org/w/api.php?action=rsd"> <link rel="canonical" href="https://en.wikipedia.org/wiki/Domperidone"> <link rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/deed.en"> <link rel="alternate" type="application/atom+xml" title="Wikipedia Atom feed" href="/w/index.php?title=Special:RecentChanges&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="login.wikimedia.org"> </head> <body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-Domperidone rootpage-Domperidone skin-vector-2022 action-view"><a class="mw-jump-link" href="#bodyContent">Jump to content</a> <div class="vector-header-container"> <header class="vector-header mw-header"> <div class="vector-header-start"> <nav class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-dropdown" class="vector-dropdown vector-main-menu-dropdown vector-button-flush-left vector-button-flush-right" title="Main menu" > <input type="checkbox" id="vector-main-menu-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-main-menu-dropdown" class="vector-dropdown-checkbox " aria-label="Main menu" > <label id="vector-main-menu-dropdown-label" for="vector-main-menu-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">Main menu</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">Main menu</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-main-menu.unpin">hide</button> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> Navigation </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-mainpage-description" class="mw-list-item"><a href="/wiki/Main_Page" title="Visit the main page [z]" accesskey="z"><span>Main page</span></a></li><li id="n-contents" class="mw-list-item"><a href="/wiki/Wikipedia:Contents" title="Guides to browsing Wikipedia"><span>Contents</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:Current_events" title="Articles related to current events"><span>Current events</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/Special:Random" title="Visit a randomly selected article [x]" accesskey="x"><span>Random article</span></a></li><li id="n-aboutsite" class="mw-list-item"><a href="/wiki/Wikipedia:About" title="Learn about Wikipedia and how it works"><span>About Wikipedia</span></a></li><li id="n-contactpage" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us" title="How to contact Wikipedia"><span>Contact us</span></a></li> </ul> </div> </div> <div id="p-interaction" class="vector-menu mw-portlet mw-portlet-interaction" > <div class="vector-menu-heading"> Contribute </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-help" class="mw-list-item"><a href="/wiki/Help:Contents" title="Guidance on how to use and edit Wikipedia"><span>Help</span></a></li><li id="n-introduction" class="mw-list-item"><a href="/wiki/Help:Introduction" title="Learn how to edit Wikipedia"><span>Learn to edit</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:Community_portal" title="The hub for editors"><span>Community portal</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/Special:RecentChanges" title="A list of recent changes to Wikipedia [r]" accesskey="r"><span>Recent changes</span></a></li><li id="n-upload" class="mw-list-item"><a href="/wiki/Wikipedia:File_upload_wizard" title="Add images or other media for use on Wikipedia"><span>Upload file</span></a></li><li id="n-specialpages" class="mw-list-item"><a href="/wiki/Special:SpecialPages"><span>Special pages</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/Main_Page" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="Wikipedia" src="/static/images/mobile/copyright/wikipedia-wordmark-en.svg" style="width: 7.5em; height: 1.125em;"> <img class="mw-logo-tagline" alt="The Free Encyclopedia" src="/static/images/mobile/copyright/wikipedia-tagline-en.svg" width="117" height="13" style="width: 7.3125em; height: 0.8125em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/Special:Search" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Search Wikipedia [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia" aria-label="Search Wikipedia" autocapitalize="sentences" title="Search Wikipedia [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="Personal tools"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="Change the appearance of the page's font size, width, and color" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="Appearance" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">Appearance</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en" class=""><span>Donate</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:CreateAccount&returnto=Domperidone" title="You are encouraged to create an account and log in; however, it is not mandatory" class=""><span>Create account</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:UserLogin&returnto=Domperidone" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o" class=""><span>Log in</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Log in and more options" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Personal tools" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Personal tools</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="User menu" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en"><span>Donate</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:CreateAccount&returnto=Domperidone" title="You are encouraged to create an account and log in; however, it is not mandatory"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Create account</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:UserLogin&returnto=Domperidone" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Log in</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Pages for logged out editors <a href="/wiki/Help:Introduction" aria-label="Learn more about editing"><span>learn more</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:MyContributions" title="A list of edits made from this IP address [y]" accesskey="y"><span>Contributions</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:MyTalk" title="Discussion about edits from this IP address [n]" accesskey="n"><span>Talk</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Contents" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Contents</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">hide</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">(Top)</div> </a> </li> <li id="toc-Medical_uses" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Medical_uses"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Medical uses</span> </div> </a> <button aria-controls="toc-Medical_uses-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Medical uses subsection</span> </button> <ul id="toc-Medical_uses-sublist" class="vector-toc-list"> <li id="toc-Nausea_and_vomiting" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Nausea_and_vomiting"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Nausea and vomiting</span> </div> </a> <ul id="toc-Nausea_and_vomiting-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Gastroparesis" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Gastroparesis"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.2</span> <span>Gastroparesis</span> </div> </a> <ul id="toc-Gastroparesis-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Lactation" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Lactation"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.3</span> <span>Lactation</span> </div> </a> <ul id="toc-Lactation-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Other_uses" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Other_uses"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.4</span> <span>Other uses</span> </div> </a> <ul id="toc-Other_uses-sublist" class="vector-toc-list"> <li id="toc-Parkinson's_disease" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Parkinson's_disease"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.4.1</span> <span>Parkinson's disease</span> </div> </a> <ul id="toc-Parkinson's_disease-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Other_gastrointestinal_uses" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Other_gastrointestinal_uses"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.4.2</span> <span>Other gastrointestinal uses</span> </div> </a> <ul id="toc-Other_gastrointestinal_uses-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Available_forms" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Available_forms"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.5</span> <span>Available forms</span> </div> </a> <ul id="toc-Available_forms-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Veterinary_uses" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Veterinary_uses"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Veterinary uses</span> </div> </a> <ul id="toc-Veterinary_uses-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Contraindications" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Contraindications"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Contraindications</span> </div> </a> <ul id="toc-Contraindications-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Side_effects" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Side_effects"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Side effects</span> </div> </a> <button aria-controls="toc-Side_effects-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Side effects subsection</span> </button> <ul id="toc-Side_effects-sublist" class="vector-toc-list"> <li id="toc-Elevated_prolactin_levels" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Elevated_prolactin_levels"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.1</span> <span>Elevated prolactin levels</span> </div> </a> <ul id="toc-Elevated_prolactin_levels-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Rare_reactions" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Rare_reactions"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.2</span> <span>Rare reactions</span> </div> </a> <ul id="toc-Rare_reactions-sublist" class="vector-toc-list"> <li id="toc-Cardiac_complications" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Cardiac_complications"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.2.1</span> <span>Cardiac complications</span> </div> </a> <ul id="toc-Cardiac_complications-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Possible_central_toxicity_in_infants" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Possible_central_toxicity_in_infants"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.2.2</span> <span>Possible central toxicity in infants</span> </div> </a> <ul id="toc-Possible_central_toxicity_in_infants-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> </ul> </li> <li id="toc-Interactions" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Interactions"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Interactions</span> </div> </a> <ul id="toc-Interactions-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Pharmacology" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Pharmacology"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Pharmacology</span> </div> </a> <button aria-controls="toc-Pharmacology-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Pharmacology subsection</span> </button> <ul id="toc-Pharmacology-sublist" class="vector-toc-list"> <li id="toc-Pharmacodynamics" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Pharmacodynamics"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.1</span> <span>Pharmacodynamics</span> </div> </a> <ul id="toc-Pharmacodynamics-sublist" class="vector-toc-list"> <li id="toc-Effects_on_prolactin_levels" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Effects_on_prolactin_levels"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.1.1</span> <span>Effects on prolactin levels</span> </div> </a> <ul id="toc-Effects_on_prolactin_levels-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Pharmacokinetics" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Pharmacokinetics"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2</span> <span>Pharmacokinetics</span> </div> </a> <ul id="toc-Pharmacokinetics-sublist" class="vector-toc-list"> <li id="toc-Absorption" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Absorption"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2.1</span> <span>Absorption</span> </div> </a> <ul id="toc-Absorption-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Distribution" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Distribution"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2.2</span> <span>Distribution</span> </div> </a> <ul id="toc-Distribution-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Metabolism" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Metabolism"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2.3</span> <span>Metabolism</span> </div> </a> <ul id="toc-Metabolism-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Elimination" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Elimination"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2.4</span> <span>Elimination</span> </div> </a> <ul id="toc-Elimination-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> </ul> </li> <li id="toc-Chemistry" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Chemistry"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Chemistry</span> </div> </a> <ul id="toc-Chemistry-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-History" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#History"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>History</span> </div> </a> <ul id="toc-History-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Society_and_culture" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Society_and_culture"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Society and culture</span> </div> </a> <button aria-controls="toc-Society_and_culture-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Society and culture subsection</span> </button> <ul id="toc-Society_and_culture-sublist" class="vector-toc-list"> <li id="toc-Generic_names" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Generic_names"> <div class="vector-toc-text"> <span class="vector-toc-numb">9.1</span> <span>Generic names</span> </div> </a> <ul id="toc-Generic_names-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Regulatory_approval" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Regulatory_approval"> <div class="vector-toc-text"> <span class="vector-toc-numb">9.2</span> <span>Regulatory approval</span> </div> </a> <ul id="toc-Regulatory_approval-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Formulations" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Formulations"> <div class="vector-toc-text"> <span class="vector-toc-numb">9.3</span> <span>Formulations</span> </div> </a> <ul id="toc-Formulations-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Research" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#Research"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>Research</span> </div> </a> <ul id="toc-Research-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">11</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Table of Contents" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Domperidone</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 31 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-31" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">31 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AF%D9%88%D9%85%D8%A8%D9%8A%D8%B1%D9%8A%D8%AF%D9%88%D9%86" title="دومبيريدون – Arabic" lang="ar" hreflang="ar" data-title="دومبيريدون" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%AF%D9%88%D9%85%D9%BE%D8%B1%DB%8C%D8%AF%D9%88%D9%86" title="دومپریدون – South Azerbaijani" lang="azb" hreflang="azb" data-title="دومپریدون" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%A1%E0%A6%AE%E0%A6%AA%E0%A7%87%E0%A6%B0%E0%A6%BF%E0%A6%A1%E0%A6%A8" title="ডমপেরিডন – Bangla" lang="bn" hreflang="bn" data-title="ডমপেরিডন" data-language-autonym="বাংলা" data-language-local-name="Bangla" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Domperidon" title="Domperidon – German" lang="de" hreflang="de" data-title="Domperidon" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Domperidona" title="Domperidona – Spanish" lang="es" hreflang="es" data-title="Domperidona" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Domperidono" title="Domperidono – Esperanto" lang="eo" hreflang="eo" data-title="Domperidono" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Donperidona" title="Donperidona – Basque" lang="eu" hreflang="eu" data-title="Donperidona" data-language-autonym="Euskara" data-language-local-name="Basque" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AF%D9%88%D9%85%D9%BE%D8%B1%DB%8C%D8%AF%D9%88%D9%86" title="دومپریدون – Persian" lang="fa" hreflang="fa" data-title="دومپریدون" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Domp%C3%A9ridone" title="Dompéridone – French" lang="fr" hreflang="fr" data-title="Dompéridone" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%A1%E0%A5%8B%E0%A4%AE%E0%A5%8D%E0%A4%AA%E0%A4%B0%E0%A4%BF%E0%A4%A1%E0%A5%8B%E0%A4%A8" title="डोम्परिडोन – Hindi" lang="hi" hreflang="hi" data-title="डोम्परिडोन" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Domperidon" title="Domperidon – Indonesian" lang="id" hreflang="id" data-title="Domperidon" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Domperidone" title="Domperidone – Italian" lang="it" hreflang="it" data-title="Domperidone" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%93%D7%95%D7%9E%D7%A4%D7%A8%D7%99%D7%93%D7%95%D7%9F" title="דומפרידון – Hebrew" lang="he" hreflang="he" data-title="דומפרידון" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-ks mw-list-item"><a href="https://ks.wikipedia.org/wiki/%DA%88%D9%88%D9%85%D9%BE%DB%8C%D8%B1%DA%88%D9%88%D9%86" title="ڈومپیرڈون – Kashmiri" lang="ks" hreflang="ks" data-title="ڈومپیرڈون" data-language-autonym="कॉशुर / کٲشُر" data-language-local-name="Kashmiri" class="interlanguage-link-target"><span>कॉशुर / کٲشُر</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Domperidonum" title="Domperidonum – Latin" lang="la" hreflang="la" data-title="Domperidonum" data-language-autonym="Latina" data-language-local-name="Latin" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Domperidon" title="Domperidon – Hungarian" lang="hu" hreflang="hu" data-title="Domperidon" data-language-autonym="Magyar" data-language-local-name="Hungarian" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Domperidon" title="Domperidon – Dutch" lang="nl" hreflang="nl" data-title="Domperidon" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%89%E3%83%B3%E3%83%9A%E3%83%AA%E3%83%89%E3%83%B3" title="ドンペリドン – Japanese" lang="ja" hreflang="ja" data-title="ドンペリドン" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%A1%E0%AC%AE%E2%80%8C%E0%AC%AA%E0%AD%87%E0%AC%B0%E0%AC%BF%E0%AC%A1%E0%AC%A8" title="ଡମ‌ପେରିଡନ – Odia" lang="or" hreflang="or" data-title="ଡମ‌ପେରିଡନ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Domperidona" title="Domperidona – Portuguese" lang="pt" hreflang="pt" data-title="Domperidona" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Domperidon%C4%83" title="Domperidonă – Romanian" lang="ro" hreflang="ro" data-title="Domperidonă" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%94%D0%BE%D0%BC%D0%BF%D0%B5%D1%80%D0%B8%D0%B4%D0%BE%D0%BD" title="Домперидон – Russian" lang="ru" hreflang="ru" data-title="Домперидон" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Domperidon" title="Domperidon – Serbian" lang="sr" hreflang="sr" data-title="Domperidon" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Domperidon" title="Domperidon – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Domperidon" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Domperidoni" title="Domperidoni – Finnish" lang="fi" hreflang="fi" data-title="Domperidoni" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%9F%E0%AF%8B%E0%AE%AE%E0%AF%8D%E0%AE%AA%E0%AE%B0%E0%AE%BF%E0%AE%9F%E0%AF%8B%E0%AE%A9%E0%AF%8D" title="டோம்பரிடோன் – Tamil" lang="ta" hreflang="ta" data-title="டோம்பரிடோன்" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%94%E0%B8%AD%E0%B8%A1%E0%B9%80%E0%B8%9E%E0%B8%A3%E0%B8%B4%E0%B9%82%E0%B8%94%E0%B8%99" title="ดอมเพริโดน – Thai" lang="th" hreflang="th" data-title="ดอมเพริโดน" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Domperidon" title="Domperidon – Turkish" lang="tr" hreflang="tr" data-title="Domperidon" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%94%D0%BE%D0%BC%D0%BF%D0%B5%D1%80%D0%B8%D0%B4%D0%BE%D0%BD" title="Домперидон – Ukrainian" lang="uk" hreflang="uk" data-title="Домперидон" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Domperidone" title="Domperidone – Vietnamese" lang="vi" hreflang="vi" data-title="Domperidone" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%A4%9A%E6%BD%98%E7%AB%8B%E9%85%AE" title="多潘立酮 – Chinese" lang="zh" hreflang="zh" data-title="多潘立酮" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q424238#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Domperidone" title="View the content page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:Domperidone" rel="discussion" title="Discuss improvements to the content page [t]" accesskey="t"><span>Talk</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Change language variant" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">English</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Views"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Domperidone"><span>Read</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Domperidone&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Domperidone&action=history" title="Past revisions of this page [h]" accesskey="h"><span>View history</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Tools" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Tools</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Tools</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">hide</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="More options" > <div class="vector-menu-heading"> Actions </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Domperidone"><span>Read</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Domperidone&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Domperidone&action=history"><span>View history</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> General </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Special:WhatLinksHere/Domperidone" title="List of all English Wikipedia pages containing links to this page [j]" accesskey="j"><span>What links here</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Special:RecentChangesLinked/Domperidone" rel="nofollow" title="Recent changes in pages linked from this page [k]" accesskey="k"><span>Related changes</span></a></li><li id="t-upload" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:File_Upload_Wizard" title="Upload files [u]" accesskey="u"><span>Upload file</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Domperidone&oldid=1277381409" title="Permanent link to this revision of this page"><span>Permanent link</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Domperidone&action=info" title="More information about this page"><span>Page information</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Special:CiteThisPage&page=Domperidone&id=1277381409&wpFormIdentifier=titleform" title="Information on how to cite this page"><span>Cite this page</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Special:UrlShortener&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FDomperidone"><span>Get shortened URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Special:QrCode&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FDomperidone"><span>Download QR code</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Print/export </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Special:DownloadAsPdf&page=Domperidone&action=show-download-screen" title="Download this page as a PDF file"><span>Download as PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Domperidone&printable=yes" title="Printable version of this page [p]" accesskey="p"><span>Printable version</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> In other projects </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Domperidone" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q424238" title="Structured data on this page hosted by Wikidata [g]" accesskey="g"><span>Wikidata item</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Peripheral D2 receptor antagonist</div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Not to be confused with <a href="/wiki/Droperidol" title="Droperidol">Droperidol</a>.</div> <p class="mw-empty-elt"> </p> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Pharmaceutical compound</div> <style data-mw-deduplicate="TemplateStyles:r1269284339">@media screen{html.skin-theme-clientpref-night .mw-parser-output .dark_mode_safe img{background-color:var(--background-color-inverted,#f8f9fa)}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .dark_mode_safe img{background-color:var(--background-color-inverted,#f8f9fa)}}</style> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Domperidone">Domperidone</span></caption><tbody><tr><td colspan="2" class="infobox-image"><span class="skin-invert-image" typeof="mw:File"><a href="/wiki/File:Domperidone_2D_structure.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Domperidone_2D_structure.svg/250px-Domperidone_2D_structure.svg.png" decoding="async" width="250" height="99" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Domperidone_2D_structure.svg/375px-Domperidone_2D_structure.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Domperidone_2D_structure.svg/500px-Domperidone_2D_structure.svg.png 2x" data-file-width="512" data-file-height="203" /></a></span></td></tr><tr><td colspan="2" class="infobox-image"><span class="bg-transparent" typeof="mw:File"><a href="/wiki/File:Domperidone-from-xtal-3D-bs-17.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Domperidone-from-xtal-3D-bs-17.png/250px-Domperidone-from-xtal-3D-bs-17.png" decoding="async" width="250" height="192" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Domperidone-from-xtal-3D-bs-17.png/375px-Domperidone-from-xtal-3D-bs-17.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Domperidone-from-xtal-3D-bs-17.png/500px-Domperidone-from-xtal-3D-bs-17.png 2x" data-file-width="3043" data-file-height="2341" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_nomenclature#Trade_names" title="Drug nomenclature">Trade names</a></th><td class="infobox-data">Motilium, others</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">Other names</th><td class="infobox-data">R-33812; R33812; KW-5338; KW5338; NSC-299589; NSC299589</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/American_Society_of_Health-System_Pharmacists" title="American Society of Health-System Pharmacists">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data"><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/cons/domperidone.html">Micromedex Detailed Consumer Information</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Pregnancy_category" title="Pregnancy category">Pregnancy<br />category</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> B2<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></li> <li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Route_of_administration" title="Route of administration">Routes of<br />administration</a></th><td class="infobox-data"><a href="/wiki/Oral_administration" title="Oral administration">By mouth</a>, <a href="/wiki/Rectal_administration" title="Rectal administration">rectal</a><sup id="cite_ref-mechanismforantiemetic_2-0" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_class" title="Drug class">Drug class</a></th><td class="infobox-data"><a href="/wiki/Dopamine_antagonist" title="Dopamine antagonist">D<sub>2</sub> receptor antagonist</a>; <a href="/wiki/Prolactin_releaser" class="mw-redirect" title="Prolactin releaser">Prolactin releaser</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><a href="/wiki/ATC_code_A03" title="ATC code A03">A03FA03</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=A03FA03">WHO</a></span>) <a href="/wiki/ATC_code_P51" class="mw-redirect" title="ATC code P51">QP51DX06</a> (<span title="www.whocc.no/atcvet"><a rel="nofollow" class="external text" href="https://www.whocc.no/atcvet/atcvet_index/?code=QP51DX06">WHO</a></span>)</li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Legal status</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> <a href="/wiki/Standard_for_the_Uniform_Scheduling_of_Medicines_and_Poisons#Schedule_4" title="Standard for the Uniform Scheduling of Medicines and Poisons">S4</a> (Prescription only)</li> <li><small><abbr class="country-name" title="Canada">CA</abbr></small>: <a href="/wiki/Prescription_drug" title="Prescription drug"> ℞-only</a><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="United Kingdom">UK</abbr>:</small> <a href="/wiki/Prescription_drug" title="Prescription drug">POM</a> (Prescription only)<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="European Union">EU</abbr>:</small> Rx-only<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;"><a href="/wiki/Pharmacokinetics" title="Pharmacokinetics">Pharmacokinetic</a> data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Bioavailability" title="Bioavailability">Bioavailability</a></th><td class="infobox-data">Oral: 13–17%<sup id="cite_ref-mechanismforantiemetic_2-1" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Rose2004_6-0" class="reference"><a href="#cite_note-Rose2004-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><br />Intramuscular: 90%<sup id="cite_ref-mechanismforantiemetic_2-2" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Plasma_protein_binding" title="Plasma protein binding">Protein binding</a></th><td class="infobox-data">~92%<sup id="cite_ref-mechanismforantiemetic_2-3" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_metabolism" title="Drug metabolism">Metabolism</a></th><td class="infobox-data"><a href="/wiki/Liver" title="Liver">Hepatic</a> (<a href="/wiki/CYP3A4" title="CYP3A4">CYP3A4</a>/<a href="/wiki/CYP3A5" title="CYP3A5">5</a>) and <a href="/wiki/Intestine" class="mw-redirect" title="Intestine">intestinal</a> (<a href="/wiki/First_pass_effect" title="First pass effect">first-pass</a>)<sup id="cite_ref-mechanismforantiemetic_2-9" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SimardMichaud2008_7-1" class="reference"><a href="#cite_note-SimardMichaud2008-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Metabolite" title="Metabolite">Metabolites</a></th><td class="infobox-data">All inactive<sup id="cite_ref-mechanismforantiemetic_2-4" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SimardMichaud2008_7-0" class="reference"><a href="#cite_note-SimardMichaud2008-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Onset_of_action" title="Onset of action">Onset of action</a></th><td class="infobox-data">30–60 minutes<sup id="cite_ref-NHS-Domperidone_8-0" class="reference"><a href="#cite_note-NHS-Domperidone-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Biological_half-life" title="Biological half-life">Elimination <span class="nowrap">half-life</span></a></th><td class="infobox-data">7–9 hours<sup id="cite_ref-EMC-Domperidone_9-0" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-5" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Rose2004_6-1" class="reference"><a href="#cite_note-Rose2004-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Excretion" title="Excretion">Excretion</a></th><td class="infobox-data"><a href="/wiki/Feces" title="Feces">Feces</a>: 66%<sup id="cite_ref-mechanismforantiemetic_2-6" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><br /><a href="/wiki/Urine" title="Urine">Urine</a>: 32%<sup id="cite_ref-mechanismforantiemetic_2-7" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><br /><a href="/wiki/Breast_milk" title="Breast milk">Breast milk</a>: small quantities<sup id="cite_ref-mechanismforantiemetic_2-8" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Identifiers</th></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC_nomenclature_of_chemistry" title="IUPAC nomenclature of chemistry">IUPAC name</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">5-Chloro-1-(1-[3-(2-oxo-2,3-dihydro-1<i>H</i>-benzo[<i>d</i>]imidazol-1-yl)propyl]piperidin-4-yl)-1<i>H</i>-benzo[<i>d</i>]imidazol-2(3<i>H</i>)-one</div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=57808-66-9">57808-66-9</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/PubChem#CID" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/3151">3151</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Guide_to_Pharmacology" title="Guide to Pharmacology">IUPHAR/BPS</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.guidetopharmacology.org"><a rel="nofollow" class="external text" href="https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=965">965</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB01184">DB01184</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.3039.html">3039</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/5587267Z69">5587267Z69</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D01745">D01745</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31515">CHEBI:31515</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/explore/compound/ChEMBL219916">ChEMBL219916</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID1045116">DTXSID1045116</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q424238#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.055.408">100.055.408</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q424238#P2566" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;color:inherit;">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Carbon">C</span><sub>22</sub><span title="Hydrogen">H</span><sub>24</sub><span title="Chlorine">Cl</span><span title="Nitrogen">N</span><sub>5</sub><span title="Oxygen">O</span><sub>2</sub></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7002425920000000000♠"></span>425.92</span> g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409" /><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=Clc1cc2c%28cc1%29N%28C%28%3DO%29N2%29C5CCN%28CCCN4c3ccccc3NC4%3DO%29CC5">Interactive image</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Melting_point" title="Melting point">Melting point</a></th><td class="infobox-data">242.5 °C (468.5 °F)</td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Clc1cc2c(cc1)N(C(=O)N2)C5CCN(CCCN4c3ccccc3NC4=O)CC5</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:FGXWKSZFVQUSTL-UHFFFAOYSA-N<sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-below"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold">  <span class="reflink plainlinks nourlexpansion"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special:ComparePages&rev1=458442916&page2=Domperidone">(verify)</a></span></span></td></tr></tbody></table> <p><b>Domperidone</b>, sold under the brand name <b>Motilium</b> among others, is a <a href="/wiki/Dopamine_antagonist" title="Dopamine antagonist">dopamine antagonist</a> <a href="/wiki/Medication" title="Medication">medication</a> which is used to treat <a href="/wiki/Nausea" title="Nausea">nausea</a> and <a href="/wiki/Vomiting" title="Vomiting">vomiting</a> and certain <a href="/wiki/Gastrointestinal_symptom" class="mw-redirect" title="Gastrointestinal symptom">gastrointestinal problems</a> like <a href="/wiki/Gastroparesis" title="Gastroparesis">gastroparesis</a> (delayed <a href="/wiki/Gastric_emptying" class="mw-redirect" title="Gastric emptying">gastric emptying</a>). It raises the level of <a href="/wiki/Prolactin" title="Prolactin">prolactin</a> in the human body and is used <a href="/wiki/Off_label" class="mw-redirect" title="Off label">off label</a> to induce and promote <a href="/wiki/Lactation" title="Lactation">breast milk production</a>.<sup id="cite_ref-mechanismforantiemetic_2-10" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-0" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> It may be taken <a href="/wiki/Oral_administration" title="Oral administration">by mouth</a> or <a href="/wiki/Rectal" class="mw-redirect" title="Rectal">rectally</a>.<sup id="cite_ref-mechanismforantiemetic_2-11" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ema_11-0" class="reference"><a href="#cite_note-ema-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mhra_12-0" class="reference"><a href="#cite_note-mhra-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Side_effect" title="Side effect">Side effects</a> may include <a href="/wiki/Headache" title="Headache">headache</a>, anxiety, <a href="/wiki/Dry_mouth" class="mw-redirect" title="Dry mouth">dry mouth</a>, <a href="/wiki/Abdominal_cramp" class="mw-redirect" title="Abdominal cramp">abdominal cramps</a>, <a href="/wiki/Diarrhea" title="Diarrhea">diarrhea</a>, and <a href="/wiki/Hyperprolactinemia" class="mw-redirect" title="Hyperprolactinemia">elevated prolactin levels</a>.<sup id="cite_ref-BNF79_13-0" class="reference"><a href="#cite_note-BNF79-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-12" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-1" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Henderson2003_14-0" class="reference"><a href="#cite_note-Henderson2003-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> Secondary to increased prolactin levels, <a href="/wiki/Breast_disorder" class="mw-redirect" title="Breast disorder">breast changes</a>, <a href="/wiki/Galactorrhea" title="Galactorrhea">milk outflow</a>, <a href="/wiki/Menstrual_disorder" title="Menstrual disorder">menstrual irregularities</a>, and <a href="/wiki/Hypogonadism" title="Hypogonadism">hypogonadism</a> can occur.<sup id="cite_ref-mechanismforantiemetic_2-13" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-2" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Henderson2003_14-1" class="reference"><a href="#cite_note-Henderson2003-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> Domperidone may also cause <a href="/wiki/QT_prolongation" class="mw-redirect" title="QT prolongation">QT prolongation</a> and has rarely been associated with serious <a href="/wiki/Cardiac_complication" class="mw-redirect" title="Cardiac complication">cardiac complications</a> such as <a href="/wiki/Sudden_cardiac_death" class="mw-redirect" title="Sudden cardiac death">sudden cardiac death</a>.<sup id="cite_ref-pmid26649742_15-0" class="reference"><a href="#cite_note-pmid26649742-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid20394569_16-0" class="reference"><a href="#cite_note-pmid20394569-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid24147629_17-0" class="reference"><a href="#cite_note-pmid24147629-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid26117678_18-0" class="reference"><a href="#cite_note-pmid26117678-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> However, the risks are small and occur more with high doses.<sup id="cite_ref-pmid26117678_18-1" class="reference"><a href="#cite_note-pmid26117678-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-MarziWeitz2015_19-0" class="reference"><a href="#cite_note-MarziWeitz2015-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> Domperidone acts as a <a href="/wiki/Peripherally_selective_drug" title="Peripherally selective drug">peripherally selective</a> <a href="/wiki/Receptor_antagonist" title="Receptor antagonist">antagonist</a> of the <a href="/wiki/Dopamine" title="Dopamine">dopamine</a> <a href="/wiki/D2_receptor" class="mw-redirect" title="D2 receptor">D<sub>2</sub></a> and <a href="/wiki/D3_receptor" class="mw-redirect" title="D3 receptor">D<sub>3</sub> receptors</a>.<sup id="cite_ref-mechanismforantiemetic_2-14" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-3" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Due to its low entry into the <a href="/wiki/Brain" title="Brain">brain</a>, the side effects of domperidone are different from those of other dopamine receptor antagonists like <a href="/wiki/Metoclopramide" title="Metoclopramide">metoclopramide</a> and it produces little in the way of <a href="/wiki/Central_nervous_system" title="Central nervous system">central nervous system</a> adverse effects.<sup id="cite_ref-mechanismforantiemetic_2-15" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-4" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> However, domperidone can nonetheless increase prolactin levels as the <a href="/wiki/Pituitary_gland" title="Pituitary gland">pituitary gland</a> is outside of the <a href="/wiki/Blood%E2%80%93brain_barrier" title="Blood–brain barrier">blood–brain barrier</a>.<sup id="cite_ref-pmid25475074_20-0" class="reference"><a href="#cite_note-pmid25475074-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p><p>Domperidone was discovered in 1974 and was introduced for medical use in 1979.<sup id="cite_ref-pmid18507654_21-0" class="reference"><a href="#cite_note-pmid18507654-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-dd_22-0" class="reference"><a href="#cite_note-dd-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-WilliamAndrewPublishing2013_23-0" class="reference"><a href="#cite_note-WilliamAndrewPublishing2013-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> It was developed by <a href="/wiki/Janssen_Pharmaceutica" class="mw-redirect" title="Janssen Pharmaceutica">Janssen Pharmaceutica</a>.<sup id="cite_ref-pmid18507654_21-1" class="reference"><a href="#cite_note-pmid18507654-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-dd_22-1" class="reference"><a href="#cite_note-dd-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> Domperidone is available <a href="/wiki/Over-the-counter" class="mw-redirect" title="Over-the-counter">over-the-counter</a> in many countries, for instance in Europe and elsewhere throughout the world.<sup id="cite_ref-FaisVermiglio2015_24-0" class="reference"><a href="#cite_note-FaisVermiglio2015-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-16" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> It is not approved for use in the United States.<sup id="cite_ref-FDA_20231212_25-0" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid15451832_26-0" class="reference"><a href="#cite_note-pmid15451832-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-17" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> However, it is available in the United States for people with severe and treatment-refractory gastrointestinal motility problems under an <a href="/wiki/Expanded_access" title="Expanded access">expanded access</a> individual-patient <a href="/wiki/Investigational_new_drug" class="mw-redirect" title="Investigational new drug">investigational new drug</a> application.<sup id="cite_ref-FDA_20231212_25-1" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> An <a href="/wiki/Structural_analog" title="Structural analog">analogue</a> of domperidone called <a href="/wiki/Deudomperidone" title="Deudomperidone">deudomperidone</a> is under development for potential use in the United States and other countries.<sup id="cite_ref-AdisInsight-Deudomperidone_27-0" class="reference"><a href="#cite_note-AdisInsight-Deudomperidone-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid33471485_28-0" class="reference"><a href="#cite_note-pmid33471485-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-WoMcCallumGonzalez2021_29-0" class="reference"><a href="#cite_note-WoMcCallumGonzalez2021-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup> </p> <style data-mw-deduplicate="TemplateStyles:r886046785">.mw-parser-output .toclimit-2 .toclevel-1 ul,.mw-parser-output .toclimit-3 .toclevel-2 ul,.mw-parser-output .toclimit-4 .toclevel-3 ul,.mw-parser-output .toclimit-5 .toclevel-4 ul,.mw-parser-output .toclimit-6 .toclevel-5 ul,.mw-parser-output .toclimit-7 .toclevel-6 ul{display:none}</style><div class="toclimit-3"><meta property="mw:PageProp/toc" /></div> <div class="mw-heading mw-heading2"><h2 id="Medical_uses">Medical uses</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=1" title="Edit section: Medical uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Nausea_and_vomiting">Nausea and vomiting</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=2" title="Edit section: Nausea and vomiting"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>There is some evidence that domperidone has <a href="/wiki/Antiemetic" title="Antiemetic">antiemetic</a> activity.<sup id="cite_ref-mechanismforantiemetic_2-18" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> It is recommended by the Canadian Headache Society for treatment of nausea associated with acute <a href="/wiki/Migraine" title="Migraine">migraine</a>.<sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Gastroparesis">Gastroparesis</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=3" title="Edit section: Gastroparesis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Gastroparesis" title="Gastroparesis">Gastroparesis</a> is a medical condition characterised by delayed emptying of the stomach when there is <u>no</u> mechanical <a href="/wiki/Gastric_outlet_obstruction" title="Gastric outlet obstruction">gastric outlet obstruction</a>. Its cause is most commonly <a href="/wiki/Idiopathic" class="mw-redirect" title="Idiopathic">idiopathic</a>, a <a href="/wiki/Diabetes" title="Diabetes">diabetic</a> complication or a result of abdominal surgery. The condition causes nausea, vomiting, <a href="/wiki/Postprandial" class="mw-redirect" title="Postprandial">fullness after eating</a>, early satiety (feeling full before the meal is finished), abdominal pain, and bloating. Domperidone can be used to increase the transit of food through the stomach by increasing <a href="/wiki/Gastrointestinal" class="mw-redirect" title="Gastrointestinal">gastrointestinal</a> <a href="/wiki/Peristalsis" title="Peristalsis">peristalsis</a> and hence to treat gastroparesis.<sup id="cite_ref-mechanismforantiemetic_2-19" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-5" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> It may be useful in idiopathic and diabetic gastroparesis.<sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9663360_32-0" class="reference"><a href="#cite_note-pmid9663360-32"><span class="cite-bracket">[</span>32<span class="cite-bracket">]</span></a></sup> However, increased rate of gastric emptying induced by drugs like domperidone does not always correlate well with relief of symptoms.<sup id="cite_ref-33" class="reference"><a href="#cite_note-33"><span class="cite-bracket">[</span>33<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Lactation">Lactation</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=4" title="Edit section: Lactation"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is used <a href="/wiki/Off-label_use" title="Off-label use">off-label</a> in some countries to stimulate <a href="/wiki/Lactation" title="Lactation">lactation</a> or enhance breast milk production, but, as of December 2023, it is not approved for that purpose in any country, and is not approved for use in humans in the United States.<sup id="cite_ref-FDA_20231212_25-2" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-FDADomperidone_34-0" class="reference"><a href="#cite_note-FDADomperidone-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup> Domperidone acts as a peripheral <a href="/wiki/Dopamine" title="Dopamine">dopamine</a> antagonist and is hypothesized to stimulate <a href="/wiki/Prolactin" title="Prolactin">prolactin</a> secretion, with a 2003 study supporting that hypothesis.<sup id="cite_ref-pmid15451832_26-1" class="reference"><a href="#cite_note-pmid15451832-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> </p><p>A 2018 meta-analysis of five randomized controlled trials found that domperidone resulted in a moderate increase of in breast milk volume for mothers of preterm infants with insufficient milk supply. The analysis also indicated that domperidone was well tolerated with no significant difference in maternal adverse events compared to placebo.<sup id="cite_ref-t992_35-0" class="reference"><a href="#cite_note-t992-35"><span class="cite-bracket">[</span>35<span class="cite-bracket">]</span></a></sup> Domperidone has no officially established dosage for increasing milk supply, but most published studies have used 10 mg three times daily for 4 to 10 days (30 mg per day).<sup id="cite_ref-NIH_36-0" class="reference"><a href="#cite_note-NIH-36"><span class="cite-bracket">[</span>36<span class="cite-bracket">]</span></a></sup> </p><p>The US <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">Food and Drug Administration</a> (FDA) has expressed concerns about serious adverse side effects and concerns about its effectiveness.<sup id="cite_ref-FDADomperidone_34-1" class="reference"><a href="#cite_note-FDADomperidone-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup> The FDA identified serious cardiac adverse events associated with domperidone use in lactating individuals, including arrhythmias, cardiac arrest, and sudden death. Additionally, discontinuation or tapering of domperidone has been linked to severe neuropsychiatric adverse events such as agitation, anxiety, and suicidal ideation. Because of these risks, the FDA strongly cautions against the use of domperidone to enhance lactation.<sup id="cite_ref-FDADomperidone_34-2" class="reference"><a href="#cite_note-FDADomperidone-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup> </p><p>A review by <a href="/wiki/Health_Canada" title="Health Canada">Health Canada</a> also found a link between the sudden discontinuation or tapering of domperidone when used off-label for lactation, and psychiatric withdrawal events, particularly daily doses greater than the maximum recommended dose of 30 mg per day.<sup id="cite_ref-HealthCanada_37-0" class="reference"><a href="#cite_note-HealthCanada-37"><span class="cite-bracket">[</span>37<span class="cite-bracket">]</span></a></sup> A 2021 study found that postpartum usage of domperidone increased across five Canadian provinces from 2004 and 2017 with usage plateauing in 2011 and a drop in usage after a 2012 Health Canada advisory warning about domperidone.<sup id="cite_ref-e088_38-0" class="reference"><a href="#cite_note-e088-38"><span class="cite-bracket">[</span>38<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Other_uses">Other uses</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=5" title="Edit section: Other uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading4"><h4 id="Parkinson's_disease"><span id="Parkinson.27s_disease"></span>Parkinson's disease</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=6" title="Edit section: Parkinson's disease"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Parkinson%27s_disease" title="Parkinson's disease">Parkinson's disease</a> is a <a href="/wiki/Neurodegenerative_disease" title="Neurodegenerative disease">degenerative neurological condition</a> where a decrease in <a href="/wiki/Dopamine" title="Dopamine">dopamine</a> in the <a href="/wiki/Brain" title="Brain">brain</a> leads to <a href="/wiki/Muscle_rigidity" class="mw-redirect" title="Muscle rigidity">rigidity</a> (stiffness of movement), <a href="/wiki/Tremor" title="Tremor">tremor</a>, and other symptoms and signs. Poor <a href="/wiki/Gastrointestinal" class="mw-redirect" title="Gastrointestinal">gastrointestinal</a> function, <a href="/wiki/Nausea" title="Nausea">nausea</a>, and <a href="/wiki/Vomiting" title="Vomiting">vomiting</a> are major problems for people with Parkinson's disease because most medications used to treat Parkinson's disease are given <a href="/wiki/Oral_administration" title="Oral administration">by mouth</a>. These <a href="/wiki/Medication" title="Medication">medications</a>, such as <a href="/wiki/Levodopa" title="Levodopa">levodopa</a>, can also cause nausea as a <a href="/wiki/Side_effect" title="Side effect">side effect</a>. Furthermore, <a href="/wiki/Antiemetic" title="Antiemetic">anti-nausea drugs</a>, such as <a href="/wiki/Metoclopramide" title="Metoclopramide">metoclopramide</a>, which do cross the <a href="/wiki/Blood%E2%80%93brain_barrier" title="Blood–brain barrier">blood–brain barrier</a>, may worsen the <a href="/wiki/Extrapyramidal_symptom" class="mw-redirect" title="Extrapyramidal symptom">extrapyramidal symptoms</a> of Parkinson's disease. Domperidone can be used to relieve nausea and gastrointestinal symptoms in Parkinson's disease; it blocks peripheral D<sub>2</sub> receptors but minimally crosses the blood-brain barrier in normal doses, so has no effect on the extrapyramidal symptoms of the disease.<sup id="cite_ref-pmid30361854_39-0" class="reference"><a href="#cite_note-pmid30361854-39"><span class="cite-bracket">[</span>39<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid18281732_40-0" class="reference"><a href="#cite_note-pmid18281732-40"><span class="cite-bracket">[</span>40<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9108986_41-0" class="reference"><a href="#cite_note-pmid9108986-41"><span class="cite-bracket">[</span>41<span class="cite-bracket">]</span></a></sup> In addition, domperidone may be useful in the treatment of <a href="/wiki/Orthostatic_hypotension" title="Orthostatic hypotension">orthostatic hypotension</a> caused by <a href="/wiki/Dopaminergic" title="Dopaminergic">dopaminergic</a> therapy in people with Parkinson's disease.<sup id="cite_ref-BacchiChimKramer2017_42-0" class="reference"><a href="#cite_note-BacchiChimKramer2017-42"><span class="cite-bracket">[</span>42<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-LiWuCui2023_43-0" class="reference"><a href="#cite_note-LiWuCui2023-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Lang2001_44-0" class="reference"><a href="#cite_note-Lang2001-44"><span class="cite-bracket">[</span>44<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-LuchsingerGrilliVelasco1998_45-0" class="reference"><a href="#cite_note-LuchsingerGrilliVelasco1998-45"><span class="cite-bracket">[</span>45<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SchofferHendersonOMaley2007_46-0" class="reference"><a href="#cite_note-SchofferHendersonOMaley2007-46"><span class="cite-bracket">[</span>46<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading4"><h4 id="Other_gastrointestinal_uses">Other gastrointestinal uses</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=7" title="Edit section: Other gastrointestinal uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone may be used in <a href="/wiki/Functional_dyspepsia" title="Functional dyspepsia">functional dyspepsia</a> in both adults and children.<sup id="cite_ref-47" class="reference"><a href="#cite_note-47"><span class="cite-bracket">[</span>47<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-48" class="reference"><a href="#cite_note-48"><span class="cite-bracket">[</span>48<span class="cite-bracket">]</span></a></sup> It has also been found effective in the treatment of <a href="/wiki/Gastroesophageal_reflux_disease" title="Gastroesophageal reflux disease">reflux</a> in children.<sup id="cite_ref-49" class="reference"><a href="#cite_note-49"><span class="cite-bracket">[</span>49<span class="cite-bracket">]</span></a></sup> However some specialists consider its risks prohibitory of the treatment of infantile reflux.<sup id="cite_ref-50" class="reference"><a href="#cite_note-50"><span class="cite-bracket">[</span>50<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Available_forms">Available forms</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=8" title="Edit section: Available forms"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is available for use by <a href="/wiki/Oral_administration" title="Oral administration">oral administration</a> in the form of <a href="/wiki/Tablet_(pharmacy)" title="Tablet (pharmacy)">tablets</a>, <a href="/wiki/Orally_disintegrating_tablet" title="Orally disintegrating tablet">orally disintegrating tablets</a> (ODTs) and <a href="/wiki/Suspension_(chemistry)" title="Suspension (chemistry)">suspension</a>, and by <a href="/wiki/Rectal_administration" title="Rectal administration">rectal administration</a> in the form of <a href="/wiki/Suppository" title="Suppository">suppositories</a>.<sup id="cite_ref-ema_11-1" class="reference"><a href="#cite_note-ema-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mhra_12-1" class="reference"><a href="#cite_note-mhra-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> The oral tablets are available in the strength of 10<span class="nowrap"> </span>mg.<sup id="cite_ref-mechanismforantiemetic_2-20" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Domperidone has been studied for use by <a href="/wiki/Intramuscular_injection" title="Intramuscular injection">intramuscular injection</a> and an <a href="/wiki/Intravenous_injection" class="mw-redirect" title="Intravenous injection">intravenous</a> formulation was previously available, but the medication is now only available in forms for oral and rectal administration.<sup id="cite_ref-mechanismforantiemetic_2-21" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Veterinary_uses">Veterinary uses</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=9" title="Edit section: Veterinary uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is used as immunotherapy to treat <a href="/wiki/Leishmania" title="Leishmania">leishmania</a> in dogs.<sup id="cite_ref-51" class="reference"><a href="#cite_note-51"><span class="cite-bracket">[</span>51<span class="cite-bracket">]</span></a></sup> </p><p>Domperidone also has an FDA-approved formulation for the prevention of fescue toxicosis in periparturient mares.<sup id="cite_ref-52" class="reference"><a href="#cite_note-52"><span class="cite-bracket">[</span>52<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Contraindications">Contraindications</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=10" title="Edit section: Contraindications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is <a href="/wiki/Contraindication" title="Contraindication">contraindicated</a> with <a href="/wiki/QT-prolonging_drug" class="mw-redirect" title="QT-prolonging drug">QT-prolonging drugs</a> like <a href="/wiki/Amiodarone" title="Amiodarone">amiodarone</a>.<sup id="cite_ref-MIMS_53-0" class="reference"><a href="#cite_note-MIMS-53"><span class="cite-bracket">[</span>53<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Side_effects">Side effects</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=11" title="Edit section: Side effects"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Side effects associated with domperidone include <a href="/wiki/Dry_mouth" class="mw-redirect" title="Dry mouth">dry mouth</a>, <a href="/wiki/Abdominal_cramp" class="mw-redirect" title="Abdominal cramp">abdominal cramps</a>, <a href="/wiki/Diarrhea" title="Diarrhea">diarrhea</a>, <a href="/wiki/Nausea" title="Nausea">nausea</a>, <a href="/wiki/Rash" title="Rash">rash</a>, <a href="/wiki/Pruritus" class="mw-redirect" title="Pruritus">itching</a>, <a href="/wiki/Urticaria" class="mw-redirect" title="Urticaria">hives</a>, and <a href="/wiki/Hyperprolactinemia" class="mw-redirect" title="Hyperprolactinemia">hyperprolactinemia</a> (the symptoms of which may include <a href="/wiki/Mammoplasia" title="Mammoplasia">breast enlargement</a>, <a href="/wiki/Galactorrhea" title="Galactorrhea">galactorrhea</a>, <a href="/wiki/Mastodynia" class="mw-redirect" title="Mastodynia">breast pain/tenderness</a>, <a href="/wiki/Gynecomastia" title="Gynecomastia">gynecomastia</a>, <a href="/wiki/Hypogonadism" title="Hypogonadism">hypogonadism</a>, and <a href="/wiki/Irregular_menstruation" title="Irregular menstruation">menstrual irregularities</a>).<sup id="cite_ref-Henderson2003_14-2" class="reference"><a href="#cite_note-Henderson2003-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p><p>Due to the blockade of D<sub>2</sub> receptors in the <a href="/wiki/Central_nervous_system" title="Central nervous system">central nervous system</a>, D<sub>2</sub> receptor antagonists like <a href="/wiki/Metoclopramide" title="Metoclopramide">metoclopramide</a> and <a href="/wiki/Antipsychotic" title="Antipsychotic">antipsychotics</a> can also produce a variety of additional side effects including <a href="/wiki/Drowsiness" class="mw-redirect" title="Drowsiness">drowsiness</a>, <a href="/wiki/Akathisia" title="Akathisia">akathisia</a>, <a href="/wiki/Psychomotor_agitation" title="Psychomotor agitation">restlessness</a>, <a href="/wiki/Insomnia" title="Insomnia">insomnia</a>, <a href="/wiki/Lassitude" class="mw-redirect" title="Lassitude">lassitude</a>, <a href="/wiki/Fatigue_(medicine)" class="mw-redirect" title="Fatigue (medicine)">fatigue</a>, <a href="/wiki/Extrapyramidal_symptom" class="mw-redirect" title="Extrapyramidal symptom">extrapyramidal symptoms</a>, <a href="/wiki/Dystonia" title="Dystonia">dystonia</a>, <a href="/wiki/Parkinsonism" title="Parkinsonism">Parkinsonian symptoms</a>, <a href="/wiki/Tardive_dyskinesia" title="Tardive dyskinesia">tardive dyskinesia</a>, and <a href="/wiki/Depression_(mood)" title="Depression (mood)">depression</a>.<sup id="cite_ref-mechanismforantiemetic_2-22" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-6" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> However, this is not the case with domperidone, because, unlike other D<sub>2</sub> receptor antagonists, it minimally crosses the <a href="/wiki/Blood%E2%80%93brain_barrier" title="Blood–brain barrier">blood–brain barrier</a>, and for this reason, is rarely associated with such side effects.<sup id="cite_ref-mechanismforantiemetic_2-23" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10332535_10-7" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> However, domperidone theoretically might be able to produce some blockade of central D<sub>2</sub> receptors at higher doses, in turn producing side effects similar to those of centrally permeable D<sub>2</sub> receptor antagonists like antipsychotics.<sup id="cite_ref-pmid24660005_54-0" class="reference"><a href="#cite_note-pmid24660005-54"><span class="cite-bracket">[</span>54<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Elevated_prolactin_levels">Elevated prolactin levels</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=12" title="Edit section: Elevated prolactin levels"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Due to D<sub>2</sub> receptor blockade, domperidone causes <a href="/wiki/Hyperprolactinemia" class="mw-redirect" title="Hyperprolactinemia">hyperprolactinemia</a>.<sup id="cite_ref-JoslinKahn2005_55-0" class="reference"><a href="#cite_note-JoslinKahn2005-55"><span class="cite-bracket">[</span>55<span class="cite-bracket">]</span></a></sup> Hyperprolactinemia can suppress the secretion of <a href="/wiki/Gonadotropin-releasing_hormone" title="Gonadotropin-releasing hormone">gonadotropin-releasing hormone</a> (GnRH) from the <a href="/wiki/Hypothalamus" title="Hypothalamus">hypothalamus</a>, in turn suppressing the secretion of <a href="/wiki/Follicle-stimulating_hormone" title="Follicle-stimulating hormone">follicle-stimulating hormone</a> (FSH) and <a href="/wiki/Luteinizing_hormone" title="Luteinizing hormone">luteinizing hormone</a> (LH) and resulting in <a href="/wiki/Hypogonadism" title="Hypogonadism">hypogonadism</a> and low levels of the <a href="/wiki/Sex_hormone" title="Sex hormone">sex hormones</a> <a href="/wiki/Estradiol" title="Estradiol">estradiol</a> and <a href="/wiki/Testosterone" title="Testosterone">testosterone</a>.<sup id="cite_ref-Jr.2010_56-0" class="reference"><a href="#cite_note-Jr.2010-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup> Accordingly, 10 to 15% of females have been reported to experience <a href="/wiki/Mammoplasia" title="Mammoplasia">mammoplasia</a> (breast enlargement), <a href="/wiki/Mastodynia" class="mw-redirect" title="Mastodynia">mastodynia</a> (breast pain/tenderness), <a href="/wiki/Galactorrhea" title="Galactorrhea">galactorrhea</a> (inappropriate or excessive milk production/secretion), and <a href="/wiki/Amenorrhea" title="Amenorrhea">amenorrhea</a> (cessation of <a href="/wiki/Menstrual_cycle" title="Menstrual cycle">menstrual cycles</a>) with domperidone therapy.<sup id="cite_ref-JoslinKahn2005_55-1" class="reference"><a href="#cite_note-JoslinKahn2005-55"><span class="cite-bracket">[</span>55<span class="cite-bracket">]</span></a></sup> Males may experience low <a href="/wiki/Libido" title="Libido">libido</a>, <a href="/wiki/Erectile_dysfunction" title="Erectile dysfunction">erectile dysfunction</a>, and impaired <a href="/wiki/Spermatogenesis" title="Spermatogenesis">spermatogenesis</a>, as well as <a href="/wiki/Galactorrhea" title="Galactorrhea">galactorrhea</a> and <a href="/wiki/Gynecomastia" title="Gynecomastia">gynecomastia</a>.<sup id="cite_ref-Jr.2010_56-1" class="reference"><a href="#cite_note-Jr.2010-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-BriggsFreeman2012_57-0" class="reference"><a href="#cite_note-BriggsFreeman2012-57"><span class="cite-bracket">[</span>57<span class="cite-bracket">]</span></a></sup> D<sub>2</sub> receptor antagonists like <a href="/wiki/Antipsychotic" title="Antipsychotic">antipsychotics</a> and domperidone may also increase the risk of <a href="/wiki/Prolactinoma" title="Prolactinoma">prolactinomas</a>, but more research is needed to confirm this.<sup id="cite_ref-pmid20455888_58-0" class="reference"><a href="#cite_note-pmid20455888-58"><span class="cite-bracket">[</span>58<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid20592331_59-0" class="reference"><a href="#cite_note-pmid20592331-59"><span class="cite-bracket">[</span>59<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid30531551_60-0" class="reference"><a href="#cite_note-pmid30531551-60"><span class="cite-bracket">[</span>60<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-DurraniVasireddyArshad2023_61-0" class="reference"><a href="#cite_note-DurraniVasireddyArshad2023-61"><span class="cite-bracket">[</span>61<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Rare_reactions">Rare reactions</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=13" title="Edit section: Rare reactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading4"><h4 id="Cardiac_complications">Cardiac complications</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=14" title="Edit section: Cardiac complications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone use is associated with an increased risk of <a href="/wiki/Sudden_cardiac_death" class="mw-redirect" title="Sudden cardiac death">sudden cardiac death</a> (by 70%)<sup id="cite_ref-pmid26649742_15-1" class="reference"><a href="#cite_note-pmid26649742-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> most likely through its prolonging effect of the cardiac <a href="/wiki/QT_interval" title="QT interval">QT interval</a> and <a href="/wiki/Ventricular_arrhythmia" class="mw-redirect" title="Ventricular arrhythmia">ventricular arrhythmias</a>.<sup id="cite_ref-62" class="reference"><a href="#cite_note-62"><span class="cite-bracket">[</span>62<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-63" class="reference"><a href="#cite_note-63"><span class="cite-bracket">[</span>63<span class="cite-bracket">]</span></a></sup> The cause is thought to be <a href="/wiki/Channel_blocker" title="Channel blocker">blockade</a> of <a href="/wiki/HERG" title="HERG">hERG</a> <a href="/wiki/Voltage-gated_potassium_channel" title="Voltage-gated potassium channel">voltage-gated potassium channels</a>.<sup id="cite_ref-pmid20394569_16-1" class="reference"><a href="#cite_note-pmid20394569-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid24147629_17-1" class="reference"><a href="#cite_note-pmid24147629-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> The risks are dose-dependent, and appear to be greatest with high/very high doses via intravenous administration and in the elderly, as well as with drugs that interact with domperidone and increase its circulating concentrations (namely <a href="/wiki/CYP3A4" title="CYP3A4">CYP3A4</a> inhibitors).<sup id="cite_ref-MarziWeitz2015_19-1" class="reference"><a href="#cite_note-MarziWeitz2015-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid26117678_18-2" class="reference"><a href="#cite_note-pmid26117678-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> Conflicting reports exist, however.<sup id="cite_ref-OrtizCooper2015_64-0" class="reference"><a href="#cite_note-OrtizCooper2015-64"><span class="cite-bracket">[</span>64<span class="cite-bracket">]</span></a></sup> In neonates and infants, QT prolongation is controversial and uncertain.<sup id="cite_ref-65" class="reference"><a href="#cite_note-65"><span class="cite-bracket">[</span>65<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-66" class="reference"><a href="#cite_note-66"><span class="cite-bracket">[</span>66<span class="cite-bracket">]</span></a></sup> </p><p>UK drug regulatory authorities (MHRA) have issued the following restriction on domperidone in 2014 due to increased risk of adverse cardiac effects:<sup id="cite_ref-MHRA2014_67-0" class="reference"><a href="#cite_note-MHRA2014-67"><span class="cite-bracket">[</span>67<span class="cite-bracket">]</span></a></sup> </p> <style data-mw-deduplicate="TemplateStyles:r1244412712">.mw-parser-output .templatequote{overflow:hidden;margin:1em 0;padding:0 32px}.mw-parser-output .templatequotecite{line-height:1.5em;text-align:left;margin-top:0}@media(min-width:500px){.mw-parser-output .templatequotecite{padding-left:1.6em}}</style><blockquote class="templatequote"><p><i>Domperidone (Motilium) is associated with a small increased risk of serious cardiac side effects. Its use is now restricted to the relief of nausea and vomiting and the dosage and duration of use have been reduced. It should no longer be used for the treatment of bloating and heartburn. Domperidone is now contraindicated in those with underlying cardiac conditions and other risk factors. Patients with these conditions and patients receiving long-term treatment with domperidone should be reassessed at a routine appointment, in light of the new advice.</i></p></blockquote> <p>However, a 2015 Australian review concluded the following:<sup id="cite_ref-pmid26117678_18-3" class="reference"><a href="#cite_note-pmid26117678-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1244412712" /><blockquote class="templatequote"><p><i>Based on the results of the two TQT (the regulatory agency gold standard for assessment of QT prolongation) domperidone does not appear to be strongly associated with QT prolongation at oral doses of 20 mg QID in healthy volunteers. Further, there are limited case reports supporting an association with cardiac dysfunction, and the frequently cited case-control studies have significant flaws. While there remains an ill-defined risk at higher systemic concentrations, especially in patients with a higher baseline risk of QT prolongation, our review does not support the view that domperidone presents intolerable risk.</i></p></blockquote> <div class="mw-heading mw-heading4"><h4 id="Possible_central_toxicity_in_infants">Possible central toxicity in infants</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=15" title="Edit section: Possible central toxicity in infants"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In Britain, a legal case involved the death of two children of a mother whose three children had all had <a href="/wiki/Hypernatraemia" class="mw-redirect" title="Hypernatraemia">hypernatraemia</a>. She was charged with poisoning the children with salt. One of the children, who was born at 28 weeks gestation with <a href="/wiki/Respiratory" class="mw-redirect" title="Respiratory">respiratory</a> complications and had a <a href="/wiki/Fundoplication" class="mw-redirect" title="Fundoplication">fundoplication</a> for <a href="/wiki/Gastroesophageal_reflux" class="mw-redirect" title="Gastroesophageal reflux">gastroesophageal reflux</a> and <a href="/wiki/Failure_to_thrive" title="Failure to thrive">failure to thrive</a> was prescribed domperidone. An <a href="/wiki/Advocate" title="Advocate">advocate</a> for the mother suggested the child may have had <a href="/wiki/Neuroleptic_malignant_syndrome" title="Neuroleptic malignant syndrome">neuroleptic malignant syndrome</a> as a side effect of domperidone due to the drug crossing the child's immature <a href="/wiki/Blood%E2%80%93brain_barrier" title="Blood–brain barrier">blood–brain barrier</a>.<sup id="cite_ref-68" class="reference"><a href="#cite_note-68"><span class="cite-bracket">[</span>68<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Interactions">Interactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=16" title="Edit section: Interactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In healthy volunteers, the <a href="/wiki/CYP3A4" title="CYP3A4">CYP3A4</a> <a href="/wiki/Enzyme_inhibitor" title="Enzyme inhibitor">inhibitor</a> <a href="/wiki/Ketoconazole" title="Ketoconazole">ketoconazole</a> increased the <a href="/wiki/Cmax_(pharmacology)" title="Cmax (pharmacology)">C<sub>max</sub></a> and <a href="/wiki/Area_under_the_curve_(pharmacokinetics)" title="Area under the curve (pharmacokinetics)">AUC</a> concentrations of domperidone by 3- to 10-fold.<sup id="cite_ref-Aronson2009_69-0" class="reference"><a href="#cite_note-Aronson2009-69"><span class="cite-bracket">[</span>69<span class="cite-bracket">]</span></a></sup> This was accompanied by a QT interval prolongation of about 10–20 milliseconds when domperidone 10 mg four times daily and ketoconazole 200 mg twice daily were administered, whereas domperidone by itself at the dosage assessed produced no such effect.<sup id="cite_ref-Aronson2009_69-1" class="reference"><a href="#cite_note-Aronson2009-69"><span class="cite-bracket">[</span>69<span class="cite-bracket">]</span></a></sup> As such, domperidone with ketoconazole or other CYP3A4 inhibitors is a potentially dangerous combination.<sup id="cite_ref-Aronson2009_69-2" class="reference"><a href="#cite_note-Aronson2009-69"><span class="cite-bracket">[</span>69<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Pharmacology">Pharmacology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=17" title="Edit section: Pharmacology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Pharmacodynamics">Pharmacodynamics</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=18" title="Edit section: Pharmacodynamics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is a <a href="/wiki/Peripherally_selective_drug" title="Peripherally selective drug">peripherally selective</a> <a href="/wiki/Dopamine" title="Dopamine">dopamine</a> <a href="/wiki/D2_receptor" class="mw-redirect" title="D2 receptor">D<sub>2</sub></a> and <a href="/wiki/D3_receptor" class="mw-redirect" title="D3 receptor">D<sub>3</sub> receptor</a> <a href="/wiki/Receptor_antagonist" title="Receptor antagonist">antagonist</a>.<sup id="cite_ref-pmid10332535_10-8" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> It has no clinically significant interaction with the <a href="/wiki/D1_receptor" class="mw-redirect" title="D1 receptor">D<sub>1</sub> receptor</a>, unlike <a href="/wiki/Metoclopramide" title="Metoclopramide">metoclopramide</a>.<sup id="cite_ref-pmid10332535_10-9" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> The medication provides relief from nausea by blocking D<sub>2</sub> receptors in the <a href="/wiki/Chemoreceptor_trigger_zone" title="Chemoreceptor trigger zone">chemoreceptor trigger zone</a> and from gastrointestinal symptoms by blocking D<sub>2</sub> receptors in the gut.<sup id="cite_ref-pmid25475074_20-1" class="reference"><a href="#cite_note-pmid25475074-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-24" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> It blocks D<sub>2</sub> receptors in the <a href="/wiki/Lactotroph" class="mw-redirect" title="Lactotroph">lactotrophs</a> of the <a href="/wiki/Anterior_pituitary" title="Anterior pituitary">anterior pituitary</a> gland increasing release of <a href="/wiki/Prolactin" title="Prolactin">prolactin</a> which in turn increases <a href="/wiki/Lactation" title="Lactation">lactation</a>.<sup id="cite_ref-pmid25475074_20-2" class="reference"><a href="#cite_note-pmid25475074-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-70" class="reference"><a href="#cite_note-70"><span class="cite-bracket">[</span>70<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-71" class="reference"><a href="#cite_note-71"><span class="cite-bracket">[</span>71<span class="cite-bracket">]</span></a></sup> Domperidone may be more useful in some patients and cause harm in others by way of the <a href="/wiki/Genotype" title="Genotype">genetics</a> of the person, such as <a href="/wiki/Polymorphism_(biology)" title="Polymorphism (biology)">polymorphisms</a> in the drug transporter <a href="/wiki/Gene" title="Gene">gene</a> <i>ABCB1</i> (which encodes <a href="/wiki/P-glycoprotein" title="P-glycoprotein">P-glycoprotein</a>), the <a href="/wiki/Voltage-gated_potassium_channel" title="Voltage-gated potassium channel">voltage-gated potassium channel</a> <i>KCNH2</i> gene (<a href="/wiki/HERG" title="HERG">hERG/K<sub>v</sub>11.1</a>), and the <a href="/wiki/Alpha-1D_adrenergic_receptor" title="Alpha-1D adrenergic receptor">α<sub>1D</sub>-adrenergic receptor</a> <i>ADRA1D</i> gene.<sup id="cite_ref-72" class="reference"><a href="#cite_note-72"><span class="cite-bracket">[</span>72<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading4"><h4 id="Effects_on_prolactin_levels">Effects on prolactin levels</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=19" title="Edit section: Effects on prolactin levels"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A single 20 mg oral dose of domperidone has been found to increase mean serum prolactin levels (measured 90 minutes post-administration) in non-lactating women from 8.1 ng/mL to 110.9 ng/mL (a 13.7-fold increase).<sup id="cite_ref-pmid10332535_10-10" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12192964_73-0" class="reference"><a href="#cite_note-pmid12192964-73"><span class="cite-bracket">[</span>73<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid3882143_74-0" class="reference"><a href="#cite_note-pmid3882143-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid7428183_75-0" class="reference"><a href="#cite_note-pmid7428183-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> This was similar to the increase in prolactin levels produced by a single 20 mg oral dose of metoclopramide (7.4 ng/mL to 124.1 ng/mL; 16.7-fold increase).<sup id="cite_ref-pmid3882143_74-1" class="reference"><a href="#cite_note-pmid3882143-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid7428183_75-1" class="reference"><a href="#cite_note-pmid7428183-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> After two weeks of repeated administration (30 mg/day in both cases), the increase in prolactin levels produced by domperidone was reduced (53.2 ng/mL; 6.6-fold above baseline), but the increase in prolactin levels produced by metoclopramide, conversely, was heightened (179.6 ng/mL; 24.3-fold above baseline).<sup id="cite_ref-pmid10332535_10-11" class="reference"><a href="#cite_note-pmid10332535-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid7428183_75-2" class="reference"><a href="#cite_note-pmid7428183-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> This indicates that acute and continuous administration of both domperidone and metoclopramide is effective in increasing prolactin levels, but that there are different effects on the secretion of prolactin with repeated use.<sup id="cite_ref-pmid3882143_74-2" class="reference"><a href="#cite_note-pmid3882143-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid7428183_75-3" class="reference"><a href="#cite_note-pmid7428183-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> The mechanism of the difference is unknown.<sup id="cite_ref-pmid7428183_75-4" class="reference"><a href="#cite_note-pmid7428183-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> The increase in prolactin levels observed with the two drugs was much greater in women than in men.<sup id="cite_ref-pmid3882143_74-3" class="reference"><a href="#cite_note-pmid3882143-74"><span class="cite-bracket">[</span>74<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid7428183_75-5" class="reference"><a href="#cite_note-pmid7428183-75"><span class="cite-bracket">[</span>75<span class="cite-bracket">]</span></a></sup> This appears to be due to the higher <a href="/wiki/Estrogen" title="Estrogen">estrogen</a> levels in women, as estrogen stimulates prolactin secretion from the <a href="/wiki/Pituitary_gland" title="Pituitary gland">pituitary gland</a>.<sup id="cite_ref-pmid7460861_76-0" class="reference"><a href="#cite_note-pmid7460861-76"><span class="cite-bracket">[</span>76<span class="cite-bracket">]</span></a></sup> </p><p>For comparison, normal prolactin levels in women are less than 20 ng/mL, prolactin levels peak at 100 to 300 ng/mL at <a href="/wiki/Parturition" class="mw-redirect" title="Parturition">parturition</a> in <a href="/wiki/Pregnancy" title="Pregnancy">pregnant</a> women, and in lactating women, prolactin levels have been found to be 90 ng/mL at 10 days postpartum and 44 ng/mL at 180 days postpartum.<sup id="cite_ref-Riordan2005_77-0" class="reference"><a href="#cite_note-Riordan2005-77"><span class="cite-bracket">[</span>77<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Becker2001_78-0" class="reference"><a href="#cite_note-Becker2001-78"><span class="cite-bracket">[</span>78<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Pharmacokinetics">Pharmacokinetics</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=20" title="Edit section: Pharmacokinetics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading4"><h4 id="Absorption">Absorption</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=21" title="Edit section: Absorption"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The <a href="/wiki/Absolute_bioavailability" class="mw-redirect" title="Absolute bioavailability">absolute bioavailability</a> of domperidone is low (13–17% or approximately 15%).<sup id="cite_ref-EMC-Domperidone_9-1" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-25" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> This is due to extensive <a href="/wiki/First-pass_metabolism" class="mw-redirect" title="First-pass metabolism">first-pass metabolism</a> in the <a href="/wiki/Intestine" class="mw-redirect" title="Intestine">intestines</a> and <a href="/wiki/Liver" title="Liver">liver</a>.<sup id="cite_ref-EMC-Domperidone_9-2" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Conversely, its bioavailability is high via <a href="/wiki/Intramuscular_injection" title="Intramuscular injection">intramuscular injection</a> (90%).<sup id="cite_ref-mechanismforantiemetic_2-26" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/Onset_of_action" title="Onset of action">onset of action</a> of domperidone taken orally is about 30 to 60 minutes.<sup id="cite_ref-NHS-Domperidone_8-1" class="reference"><a href="#cite_note-NHS-Domperidone-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-27" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Peak levels of domperidone following an oral dose occur after about 60 minutes.<sup id="cite_ref-EMC-Domperidone_9-3" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Domperidone exposure increases proportionally with doses in the 10 to 20 mg dose range.<sup id="cite_ref-EMC-Domperidone_9-4" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> There is a 2- to 3-fold accumulation in levels of domperidone with frequent repeated oral administration of domperidone (four times per day (every 5 hours) for 4 days).<sup id="cite_ref-EMC-Domperidone_9-5" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The oral <a href="/wiki/Bioavailability" title="Bioavailability">bioavailability</a> of domperidone is somewhat increased, and time to peak slightly increased when it is taken with food and bioavailability is decreased by prior concomitant administration of <a href="/wiki/Cimetidine" title="Cimetidine">cimetidine</a> and <a href="/wiki/Sodium_bicarbonate" title="Sodium bicarbonate">sodium bicarbonate</a>.<sup id="cite_ref-EMC-Domperidone_9-6" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading4"><h4 id="Distribution">Distribution</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=22" title="Edit section: Distribution"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The <a href="/wiki/Plasma_protein_binding" title="Plasma protein binding">plasma protein binding</a> of domperidone is 91 to 93%.<sup id="cite_ref-EMC-Domperidone_9-7" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/Tissue_distribution" class="mw-redirect" title="Tissue distribution">tissue distribution</a> of domperidone based on animal studies is wide, but concentrations are low in the brain.<sup id="cite_ref-EMC-Domperidone_9-8" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The drug is a <a href="/wiki/Substrate_(chemistry)#Bioavailability" title="Substrate (chemistry)">substrate</a> for the <a href="/wiki/P-glycoprotein" title="P-glycoprotein">P-glycoprotein</a> (ABCB1) transporter, and animal studies suggest that this is the reason for the low <a href="/wiki/Central_nervous_system" title="Central nervous system">central nervous system</a> penetration of domperidone.<sup id="cite_ref-BardalWaechter2011_79-0" class="reference"><a href="#cite_note-BardalWaechter2011-79"><span class="cite-bracket">[</span>79<span class="cite-bracket">]</span></a></sup> Small amounts of domperidone cross the <a href="/wiki/Placenta" title="Placenta">placenta</a> in animals.<sup id="cite_ref-EMC-Domperidone_9-9" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading4"><h4 id="Metabolism">Metabolism</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=23" title="Edit section: Metabolism"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is extensively <a href="/wiki/Metabolism" title="Metabolism">metabolized</a> in the <a href="/wiki/Liver" title="Liver">liver</a> and <a href="/wiki/Intestine" class="mw-redirect" title="Intestine">intestines</a> with oral administration.<sup id="cite_ref-EMC-Domperidone_9-10" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SimardMichaud2008_7-2" class="reference"><a href="#cite_note-SimardMichaud2008-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid26059917_80-0" class="reference"><a href="#cite_note-pmid26059917-80"><span class="cite-bracket">[</span>80<span class="cite-bracket">]</span></a></sup> This occurs via <a href="/wiki/Hydroxylation" title="Hydroxylation">hydroxylation</a> and <a href="/wiki/N-dealkylation" class="mw-redirect" title="N-dealkylation">N-dealkylation</a>.<sup id="cite_ref-EMC-Domperidone_9-11" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Domperidone is almost exclusively metabolized by <a href="/wiki/CYP3A4" title="CYP3A4">CYP3A4</a>/<a href="/wiki/CYP3A5" title="CYP3A5">5</a>, though minor contributions by <a href="/wiki/CYP1A2" title="CYP1A2">CYP1A2</a>, <a href="/wiki/CYP2D6" title="CYP2D6">CYP2D6</a>, and <a href="/wiki/CYP2C8" title="CYP2C8">CYP2C8</a> have been reported.<sup id="cite_ref-pmid26059917_80-1" class="reference"><a href="#cite_note-pmid26059917-80"><span class="cite-bracket">[</span>80<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SimardMichaud2008_7-3" class="reference"><a href="#cite_note-SimardMichaud2008-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> CYP3A4 is the major enzyme involved in the N-dealkylation of domperidone, while CYP3A4, CYP1A2, and <a href="/wiki/CYP2E1" title="CYP2E1">CYP2E1</a> are involved in its aromatic hydroxylation.<sup id="cite_ref-EMC-Domperidone_9-12" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> All of the <a href="/wiki/Metabolite" title="Metabolite">metabolites</a> of domperidone are inactive as D<sub>2</sub> receptor ligands.<sup id="cite_ref-mechanismforantiemetic_2-28" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-SimardMichaud2008_7-4" class="reference"><a href="#cite_note-SimardMichaud2008-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Overall and peak levels of domperidone are increased by about 2.9- and 1.5-fold in moderate <a href="/wiki/Hepatic_impairment" class="mw-redirect" title="Hepatic impairment">hepatic impairment</a>, respectively.<sup id="cite_ref-EMC-Domperidone_9-13" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading4"><h4 id="Elimination">Elimination</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=24" title="Edit section: Elimination"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is <a href="/wiki/Elimination_(pharmacology)" title="Elimination (pharmacology)">eliminated</a> 31% in urine and 66% in feces.<sup id="cite_ref-EMC-Domperidone_9-14" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The proportion of domperidone excreted unchanged is small (10% in feces and 1% in urine).<sup id="cite_ref-EMC-Domperidone_9-15" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/Biological_half-life" title="Biological half-life">elimination half-life</a> of domperidone is about 7 to 9 hours in healthy individuals.<sup id="cite_ref-EMC-Domperidone_9-16" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-29" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> However, the elimination half-life of domperidone can be prolonged to 20 hours in people with severe <a href="/wiki/Renal_dysfunction" class="mw-redirect" title="Renal dysfunction">renal dysfunction</a>.<sup id="cite_ref-EMC-Domperidone_9-17" class="reference"><a href="#cite_note-EMC-Domperidone-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-mechanismforantiemetic_2-30" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Chemistry">Chemistry</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=25" title="Edit section: Chemistry"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone is a derivative of <a href="/wiki/2-Benzimidazolinone" class="mw-redirect" title="2-Benzimidazolinone">benzimidazolinone</a>. It is structurally related to <a href="/wiki/Butyrophenone" title="Butyrophenone">butyrophenone</a> <a href="/wiki/Neuroleptic" class="mw-redirect" title="Neuroleptic">neuroleptics</a> like <a href="/wiki/Haloperidol" title="Haloperidol">haloperidol</a>.<sup id="cite_ref-HospitalFormulary1991_81-0" class="reference"><a href="#cite_note-HospitalFormulary1991-81"><span class="cite-bracket">[</span>81<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-BiggioCosta2013_82-0" class="reference"><a href="#cite_note-BiggioCosta2013-82"><span class="cite-bracket">[</span>82<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="History">History</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=26" title="Edit section: History"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone was synthesized at <a href="/wiki/Janssen_Pharmaceutica" class="mw-redirect" title="Janssen Pharmaceutica">Janssen Pharmaceutica</a> in 1974 following their research on <a href="/wiki/Antipsychotic" title="Antipsychotic">antipsychotic drugs</a>.<sup id="cite_ref-dd_22-2" class="reference"><a href="#cite_note-dd-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid18507654_21-2" class="reference"><a href="#cite_note-pmid18507654-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> Janssen pharmacologists discovered that some antipsychotic drugs had a significant effect on <a href="/wiki/Dopamine_receptor" title="Dopamine receptor">dopamine receptors</a> in the <a href="/wiki/Chemoreceptor_trigger_zone" title="Chemoreceptor trigger zone">central chemoreceptor trigger zone</a> that regulated <a href="/wiki/Vomiting" title="Vomiting">vomiting</a>, and started searching for a dopamine <a href="/wiki/Receptor_antagonist" title="Receptor antagonist">antagonist</a> that would not pass the <a href="/wiki/Blood%E2%80%93brain_barrier" title="Blood–brain barrier">blood–brain barrier</a>, thereby being free of the <a href="/wiki/Extrapyramidal_symptoms" title="Extrapyramidal symptoms">extrapyramidal side effects</a> that were associated with drugs of this type.<sup id="cite_ref-dd_22-3" class="reference"><a href="#cite_note-dd-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> This led to the discovery of domperidone as a strong antiemetic with minimal central effects.<sup id="cite_ref-dd_22-4" class="reference"><a href="#cite_note-dd-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-83" class="reference"><a href="#cite_note-83"><span class="cite-bracket">[</span>83<span class="cite-bracket">]</span></a></sup> Domperidone was <a href="/wiki/Patent" title="Patent">patented</a> in the United States in 1978, with the patent filed in 1976<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2022)">citation needed</span></a></i>]</sup>. In 1979, domperidone was first marketed, under the brand name Motilium, in Switzerland and West Germany.<sup id="cite_ref-WilliamAndrewPublishing2013_23-1" class="reference"><a href="#cite_note-WilliamAndrewPublishing2013-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> Domperidone was subsequently introduced in the forms of <a href="/wiki/Orally_disintegrating_tablet" title="Orally disintegrating tablet">orally disintegrating tablets</a> (based on <a href="/wiki/Zydis" title="Zydis">Zydis</a> technology) in 1999.<sup id="cite_ref-84" class="reference"><a href="#cite_note-84"><span class="cite-bracket">[</span>84<span class="cite-bracket">]</span></a></sup> </p><p>In April 2014, the Coordination Group for Mutual Recognition and Decentralised Procedures – Human (CMDh) published an official press release suggesting restricting the use of domperidone-containing medicines. It also approved earlier published suggestions by <a href="/wiki/European_Medicines_Agency" title="European Medicines Agency">Pharmacovigilance Risk Assessment Committee (PRAC)</a> to use domperidone only for treating <a href="/wiki/Nausea" title="Nausea">nausea</a> and <a href="/wiki/Vomiting" title="Vomiting">vomiting</a> and reduce maximum daily dosage to 10<a href="/wiki/Orders_of_magnitude_(mass)" title="Orders of magnitude (mass)">mg</a>.<sup id="cite_ref-ema_11-2" class="reference"><a href="#cite_note-ema-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Society_and_culture">Society and culture</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=27" title="Edit section: Society and culture"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Generic_names">Generic names</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=28" title="Edit section: Generic names"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><i>Domperidone</i> is the <a href="/wiki/Generic_term" class="mw-redirect" title="Generic term">generic name</a> of the drug and its <a href="/wiki/International_Nonproprietary_Name" class="mw-redirect" title="International Nonproprietary Name"><abbr title="International Nonproprietary Name">INN</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip International Nonproprietary Name</span>, <a href="/wiki/United_States_Adopted_Name" title="United States Adopted Name"><abbr title="United States Adopted Name">USAN</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip United States Adopted Name</span>, <a href="/wiki/British_Approved_Name" title="British Approved Name"><abbr title="British Approved Name">BAN</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip British Approved Name</span>, and <a href="/wiki/Japanese_Accepted_Name" title="Japanese Accepted Name"><abbr title="Japanese Accepted Name">JAN</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Japanese Accepted Name</span>.<sup id="cite_ref-Elks2014_85-0" class="reference"><a href="#cite_note-Elks2014-85"><span class="cite-bracket">[</span>85<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-IndexNominum2000_86-0" class="reference"><a href="#cite_note-IndexNominum2000-86"><span class="cite-bracket">[</span>86<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Drugs.com_87-0" class="reference"><a href="#cite_note-Drugs.com-87"><span class="cite-bracket">[</span>87<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Regulatory_approval">Regulatory approval</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=29" title="Edit section: Regulatory approval"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>It was reported in 2007 that domperidone is available in 58 countries,<sup id="cite_ref-mechanismforantiemetic_2-31" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> but the uses or <i>indications</i> of domperidone vary between nations. In Italy it is used in the treatment of <a href="/wiki/Gastroesophageal_reflux_disease" title="Gastroesophageal reflux disease">gastroesophageal reflux disease</a> and in Canada, the drug is indicated in upper gastrointestinal motility disorders and to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents.<sup id="cite_ref-88" class="reference"><a href="#cite_note-88"><span class="cite-bracket">[</span>88<span class="cite-bracket">]</span></a></sup> In the United Kingdom, domperidone is only indicated for the treatment of nausea and vomiting and the treatment duration is usually limited to 1 week. </p><p>In the United States, domperidone is not a legally marketed human drug and it is not approved for sale in the United States.<sup id="cite_ref-FDA_20231212_25-3" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> In June 2004, the <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">Food and Drug Administration</a> (FDA) issued a warning that distributing any domperidone-containing products is illegal.<sup id="cite_ref-FDA_20231212_25-4" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> </p><p>It is available <a href="/wiki/Over-the-counter" class="mw-redirect" title="Over-the-counter">over-the-counter</a> to treat <a href="/wiki/Gastroesophageal_reflux_disease" title="Gastroesophageal reflux disease">gastroesophageal reflux disease</a> and functional dyspepsia in many countries, such as Ireland, the Netherlands, Italy, South Africa, Mexico, India, Chile, and China.<sup id="cite_ref-FaisVermiglio2015_24-1" class="reference"><a href="#cite_note-FaisVermiglio2015-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p><p>Domperidone is not approved for use in the United States.<sup id="cite_ref-FDA_20231212_25-5" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> There is an exception for use in people with treatment-refractory gastrointestinal symptoms under an FDA <a href="/wiki/Investigational_New_Drug" title="Investigational New Drug">Investigational New Drug</a> application.<sup id="cite_ref-mechanismforantiemetic_2-32" class="reference"><a href="#cite_note-mechanismforantiemetic-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-FDA_20231212_25-6" class="reference"><a href="#cite_note-FDA_20231212-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Formulations">Formulations</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=30" title="Edit section: Formulations"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <table class="wikitable collapsible collapsed" style="font-size:small; width:100%;"> <tbody><tr> <th colspan="4">Formulations </th></tr> <tr> <th>Nation </th> <th>Manufacturer </th> <th>Brand </th> <th>Formulations </th></tr> <tr> <td>Australia</td> <td>Janssen–Cilag</td> <td>Motilium</td> <td>10 mg scored tablets<sup id="cite_ref-MIMS_53-1" class="reference"><a href="#cite_note-MIMS-53"><span class="cite-bracket">[</span>53<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Belgium and the Netherlands</td> <td>-</td> <td>Motilium</td> <td>From 2013 only by prescription in Belgium.<sup id="cite_ref-89" class="reference"><a href="#cite_note-89"><span class="cite-bracket">[</span>89<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Bangladesh</td> <td>Square</td> <td>Motigut</td> <td>10 mg scored tablets </td></tr> <tr> <td>Bangladesh</td> <td>Orion Pharma</td> <td>Cosy</td> <td>10 mg scored tablets </td></tr> <tr> <td>Bangladesh</td> <td>Astra Pharma</td> <td>Domperon</td> <td>10 mg scored tablets </td></tr> <tr> <td>Bangladesh</td> <td>-</td> <td>Ridon</td> <td>- </td></tr> <tr> <td>Canada</td> <td>-</td> <td>Motilium (1985–2002)</td> <td>Generic brands available </td></tr> <tr> <td>France</td> <td>Janssen</td> <td>Motilium</td> <td>10 mg tablets only with prescription generic domperidone available </td></tr> <tr> <td>Greece</td> <td>Johnson & Johnson Hellas</td> <td>Cilroton</td> <td>10 mg scored tablets </td></tr> <tr> <td>India</td> <td>Salius Pharma</td> <td>Escacid DXR</td> <td>pantoprazole 40 mg and domperidone SR 30 mg </td></tr> <tr> <td>India</td> <td>FDC Pharmaceuticals</td> <td>Pepcia-D</td> <td>Rabeprazole 20 mg and Domperidone SR 30 mg </td></tr> <tr> <td>India</td> <td>Rhubarb pharmaceuticals</td> <td>-</td> <td>domperidone 5, 10 and 20 mg tablets. </td></tr> <tr> <td>India</td> <td><a href="/wiki/Ipca_Laboratories" title="Ipca Laboratories">Ipca Laboratories</a>, Mumbai</td> <td>Domperi suspension</td> <td>domperidone 1 mg/ml, 30 ml suspension.<sup id="cite_ref-90" class="reference"><a href="#cite_note-90"><span class="cite-bracket">[</span>90<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>India</td> <td>Torrent pharmaceuticals</td> <td>Domstal</td> <td>-<sup id="cite_ref-91" class="reference"><a href="#cite_note-91"><span class="cite-bracket">[</span>91<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>India</td> <td>Ozone pharmaceuticals and chemicals</td> <td>Pantazone-D</td> <td>10 mg domperidone and 40 mg pantoprazole </td></tr> <tr> <td>India</td> <td>Chimak Health Care</td> <td>Pancert D</td> <td>10 mg Domperidone and 40 mg pantoprazole </td></tr> <tr> <td>India</td> <td>Draavin Pharma</td> <td>Draaci-XD</td> <td>Pantaprazole 40 mg and Domperione 30 mg </td></tr> <tr> <td>Indonesia</td> <td>Gratia Husada Farma (HUFA)</td> <td>Hufadon</td> <td>10 mg caplet </td></tr> <tr> <td>Indonesia</td> <td>Mutiara Mukti Farma</td> <td>Omedom</td> <td>10 mg tablet </td></tr> <tr> <td>Indonesia</td> <td>IFARS</td> <td>Vesperum</td> <td>10 mg tablet </td></tr> <tr> <td>Indonesia</td> <td>Dexa Medica</td> <td>Vometa FT</td> <td>10 mg tablet </td></tr> <tr> <td>Indonesia</td> <td>Sanbe</td> <td>Vosedon</td> <td>domperidone 5 mg/ml, 60 ml suspension </td></tr> <tr> <td>Iran</td> <td>Abidi Pharmaceutical Co.</td> <td>MOTiDON</td> <td>10 mg tablet </td></tr> <tr> <td>Ireland</td> <td>McNeil Healthcare</td> <td>Motilium</td> <td>10 mg <a href="/wiki/Orally_disintegrating_tablet" title="Orally disintegrating tablet">orally disintegrating tablet (ODT)</a> </td></tr> <tr> <td>Italy</td> <td>-</td> <td>Peridon</td> <td>domperidone 10 mg tablets; 30 ml suspension </td></tr> <tr> <td>Lithuania</td> <td>Johnson & Johnson</td> <td>Motilium</td> <td>- </td></tr> <tr> <td>Pakistan</td> <td>Barrett Hodgson Pakistan</td> <td>Domel</td> <td> </td></tr> <tr> <td>Pakistan</td> <td>Johnson & Johnson Pakistan</td> <td>Motilium-v</td> <td>domperidone 10 mg tablets; 30 ml suspension </td></tr> <tr> <td>Pakistan</td> <td>ATCO Laboratories Limited</td> <td>Vomilux</td> <td>domperidone 10 mg tablets </td></tr> <tr> <td>Pakistan</td> <td>Aspin Pharma (Pvt) Limited</td> <td>Motilium</td> <td>domperidone 10 mg tablets </td></tr> <tr> <td>Philippines</td> <td>Health Saver Pharma</td> <td>Abdopen</td> <td>- </td></tr> <tr> <td>Philippines</td> <td>United Laboratories, Inc.</td> <td>GI Norm</td> <td>- </td></tr> <tr> <td>Philippines</td> <td>Glorious Dexa Mandaya</td> <td>Vometa</td> <td>domperidone 1 mg/mL oral suspension, 1 mg/mL oral drops </td></tr> <tr> <td>Philippines</td> <td>Glorious Dexa Mandaya</td> <td>Vometa FT</td> <td>domperidone 10 mg fast-melting tablets </td></tr> <tr> <td>Portugal</td> <td>Medinfar</td> <td>Cinet</td> <td>domperidone 1 mg/ml oral suspension (200 ml) </td></tr> <tr> <td>Russia</td> <td>Janssen Pharmaceutica</td> <td>Motilium</td> <td>domperidone 10 mg film-coated tablets & ODT; 1 mg/ml suspension (100 ml) </td></tr> <tr> <td>-</td> <td>OBL Pharm</td> <td>Passagix</td> <td>domperidone 10 mg film-coated tablets & chewable tablets </td></tr> <tr> <td>-</td> <td><a href="/wiki/Dr._Reddy%27s" class="mw-redirect" title="Dr. Reddy's">Dr. Reddy's Laboratories</a></td> <td>Omez D</td> <td>domperidone/omeprazole (10 mg/10 mg) </td></tr> <tr> <td>Saudi Arabia</td> <td>JamJoom Pharmaceuticals</td> <td>Dompy</td> <td>Domperidone 10 mg tablets </td></tr> <tr> <td>Spain </td> <td>Laboratorios Dr. Esteve, SA </td> <td>Motilium </td> <td>domperidone 1 mg/ml oral suspension (200 ml) </td></tr> <tr> <td>Sweden</td> <td>Ebb medical</td> <td>Domperidon Ebb (2013)</td> <td>domperidone 10 mg ODT and peppermint </td></tr> <tr> <td>Syrian Arab Republic</td> <td>Oubari Pharma</td> <td>Motin</td> <td>Domperidone 10 mg Tablets and 1 mg/ml Oral Suspension </td></tr> <tr> <td>Taiwan</td> <td>-</td> <td>Dotitone</td> <td>- </td></tr> <tr> <td>Thailand</td> <td>-</td> <td>Motilium M</td> <td>- </td></tr> <tr> <td>Turkey</td> <td>Saba</td> <td>Motinorm</td> <td>- </td></tr> <tr> <td>-</td> <td><a href="/wiki/GlaxoSmithKline" class="mw-redirect" title="GlaxoSmithKline">GlaxoSmithKline</a></td> <td>Motinorm</td> <td>- </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=31" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Domperidone has been studied as a potential <a href="/wiki/Hormonal_contraceptive" class="mw-redirect" title="Hormonal contraceptive">hormonal contraceptive</a> to prevent <a href="/wiki/Pregnancy" title="Pregnancy">pregnancy</a> in women.<sup id="cite_ref-HofmeyrVan_Iddekinge2009_92-0" class="reference"><a href="#cite_note-HofmeyrVan_Iddekinge2009-92"><span class="cite-bracket">[</span>92<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Domperidone&action=edit&section=32" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2023-PI-02610-1">"Motilium Product Information"</a>. <i><a href="/wiki/Therapeutic_Goods_Administration" title="Therapeutic Goods Administration">Therapeutic Goods Administration</a> (TGA)</i>. 10 June 2024<span class="reference-accessdate">. Retrieved <span class="nowrap">10 June</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Therapeutic+Goods+Administration+%28TGA%29&rft.atitle=Motilium+Product+Information&rft.date=2024-06-10&rft_id=https%3A%2F%2Fwww.ebs.tga.gov.au%2Febs%2Fpicmi%2Fpicmirepository.nsf%2Fpdf%3FOpenAgent%26id%3DCP-2023-PI-02610-1&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-mechanismforantiemetic-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-mechanismforantiemetic_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-7"><sup><i><b>h</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-8"><sup><i><b>i</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-9"><sup><i><b>j</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-10"><sup><i><b>k</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-11"><sup><i><b>l</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-12"><sup><i><b>m</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-13"><sup><i><b>n</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-14"><sup><i><b>o</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-15"><sup><i><b>p</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-16"><sup><i><b>q</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-17"><sup><i><b>r</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-18"><sup><i><b>s</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-19"><sup><i><b>t</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-20"><sup><i><b>u</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-21"><sup><i><b>v</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-22"><sup><i><b>w</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-23"><sup><i><b>x</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-24"><sup><i><b>y</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-25"><sup><i><b>z</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-26"><sup><i><b>aa</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-27"><sup><i><b>ab</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-28"><sup><i><b>ac</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-29"><sup><i><b>ad</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-30"><sup><i><b>ae</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-31"><sup><i><b>af</b></i></sup></a> <a href="#cite_ref-mechanismforantiemetic_2-32"><sup><i><b>ag</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFReddymasuSoykanMcCallum2007" class="citation journal cs1">Reddymasu SC, Soykan I, McCallum RW (September 2007). "Domperidone: review of pharmacology and clinical applications in gastroenterology". <i>The American Journal of Gastroenterology</i>. <b>102</b> (9): <span class="nowrap">2036–</span>2045. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1572-0241.2007.01255.x">10.1111/j.1572-0241.2007.01255.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17488253">17488253</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:22575456">22575456</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+American+Journal+of+Gastroenterology&rft.atitle=Domperidone%3A+review+of+pharmacology+and+clinical+applications+in+gastroenterology&rft.volume=102&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E2036-%3C%2Fspan%3E2045&rft.date=2007-09&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A22575456%23id-name%3DS2CID&rft_id=info%3Apmid%2F17488253&rft_id=info%3Adoi%2F10.1111%2Fj.1572-0241.2007.01255.x&rft.aulast=Reddymasu&rft.aufirst=SC&rft.au=Soykan%2C+I&rft.au=McCallum%2C+RW&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=10691">"Motilium product information"</a>. <i><a href="/wiki/Health_Canada" title="Health Canada">Health Canada</a></i>. 7 January 2002<span class="reference-accessdate">. Retrieved <span class="nowrap">10 June</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Health+Canada&rft.atitle=Motilium+product+information&rft.date=2002-01-07&rft_id=https%3A%2F%2Fhealth-products.canada.ca%2Fdpd-bdpp%2Finfo%3Flang%3Deng%26code%3D10691&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.medicines.org.uk/emc/product/4177/smpc">"Motilium Summary of Product Characteristics (SmPC)"</a>. <i>(emc)</i>. 11 March 2024<span class="reference-accessdate">. Retrieved <span class="nowrap">10 June</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=%28emc%29&rft.atitle=Motilium+Summary+of+Product+Characteristics+%28SmPC%29&rft.date=2024-03-11&rft_id=https%3A%2F%2Fwww.medicines.org.uk%2Femc%2Fproduct%2F4177%2Fsmpc&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/medicines/human/referrals/motilium">"Motilium referral"</a>. <i><a href="/wiki/European_Medicines_Agency" title="European Medicines Agency">European Medicines Agency</a> (EMA)</i>. 31 October 2000<span class="reference-accessdate">. Retrieved <span class="nowrap">10 June</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=European+Medicines+Agency+%28EMA%29&rft.atitle=Motilium+referral&rft.date=2000-10-31&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fen%2Fmedicines%2Fhuman%2Freferrals%2Fmotilium&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Rose2004-6"><span class="mw-cite-backlink">^ <a href="#cite_ref-Rose2004_6-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Rose2004_6-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRose2004" class="citation book cs1">Rose S (October 2004). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=1W0JYuzTZsAC&pg=PA523"><i>Gastrointestinal and Hepatobiliary Pathophysiology</i></a>. Hayes Barton Press. pp. 523–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-59377-181-2" title="Special:BookSources/978-1-59377-181-2"><bdi>978-1-59377-181-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Gastrointestinal+and+Hepatobiliary+Pathophysiology&rft.pages=523-&rft.pub=Hayes+Barton+Press&rft.date=2004-10&rft.isbn=978-1-59377-181-2&rft.aulast=Rose&rft.aufirst=S&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D1W0JYuzTZsAC%26pg%3DPA523&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span><sup class="noprint Inline-Template"><span style="white-space: nowrap;">[<i><a href="/wiki/Wikipedia:Link_rot" title="Wikipedia:Link rot"><span title=" Dead link tagged August 2023">permanent dead link</span></a></i><span style="visibility:hidden; color:transparent; padding-left:2px">‍</span>]</span></sup></span> </li> <li id="cite_note-SimardMichaud2008-7"><span class="mw-cite-backlink">^ <a href="#cite_ref-SimardMichaud2008_7-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-SimardMichaud2008_7-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-SimardMichaud2008_7-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-SimardMichaud2008_7-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-SimardMichaud2008_7-4"><sup><i><b>e</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSimardMichaudGibbsMassé2008" class="citation journal cs1">Simard C, Michaud V, Gibbs B, Massé R, Lessard E, Turgeon J (2008). "Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone". <i>Xenobiotica; the Fate of Foreign Compounds in Biological Systems</i>. <b>34</b> (<span class="nowrap">11–</span>12): <span class="nowrap">1013–</span>1023. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1080%2F00498250400015301">10.1080/00498250400015301</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15801545">15801545</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:27426219">27426219</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Xenobiotica%3B+the+Fate+of+Foreign+Compounds+in+Biological+Systems&rft.atitle=Identification+of+the+cytochrome+P450+enzymes+involved+in+the+metabolism+of+domperidone&rft.volume=34&rft.issue=%3Cspan+class%3D%22nowrap%22%3E11%E2%80%93%3C%2Fspan%3E12&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1013-%3C%2Fspan%3E1023&rft.date=2008&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A27426219%23id-name%3DS2CID&rft_id=info%3Apmid%2F15801545&rft_id=info%3Adoi%2F10.1080%2F00498250400015301&rft.aulast=Simard&rft.aufirst=C&rft.au=Michaud%2C+V&rft.au=Gibbs%2C+B&rft.au=Mass%C3%A9%2C+R&rft.au=Lessard%2C+E&rft.au=Turgeon%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-NHS-Domperidone-8"><span class="mw-cite-backlink">^ <a href="#cite_ref-NHS-Domperidone_8-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-NHS-Domperidone_8-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.nhs.uk/medicines/domperidone/">"Domperidone: Anti-sickness medicine used to treat nausea and vomiting"</a>. 7 January 2020.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Domperidone%3A+Anti-sickness+medicine+used+to+treat+nausea+and+vomiting&rft.date=2020-01-07&rft_id=https%3A%2F%2Fwww.nhs.uk%2Fmedicines%2Fdomperidone%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-EMC-Domperidone-9"><span class="mw-cite-backlink">^ <a href="#cite_ref-EMC-Domperidone_9-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-7"><sup><i><b>h</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-8"><sup><i><b>i</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-9"><sup><i><b>j</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-10"><sup><i><b>k</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-11"><sup><i><b>l</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-12"><sup><i><b>m</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-13"><sup><i><b>n</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-14"><sup><i><b>o</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-15"><sup><i><b>p</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-16"><sup><i><b>q</b></i></sup></a> <a href="#cite_ref-EMC-Domperidone_9-17"><sup><i><b>r</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.medicines.org.uk/emc/product/556/smpc">"Domperidone 10mg Tablets - Summary of Product Characteristics (SMPC) - (Emc)"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Domperidone+10mg+Tablets+-+Summary+of+Product+Characteristics+%28SMPC%29+-+%28Emc%29&rft_id=https%3A%2F%2Fwww.medicines.org.uk%2Femc%2Fproduct%2F556%2Fsmpc&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid10332535-10"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid10332535_10-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-7"><sup><i><b>h</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-8"><sup><i><b>i</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-9"><sup><i><b>j</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-10"><sup><i><b>k</b></i></sup></a> <a href="#cite_ref-pmid10332535_10-11"><sup><i><b>l</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBarone1999" class="citation journal cs1">Barone JA (April 1999). "Domperidone: a peripherally acting dopamine2-receptor antagonist". <i>The Annals of Pharmacotherapy</i>. <b>33</b> (4): <span class="nowrap">429–</span>440. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1345%2Faph.18003">10.1345/aph.18003</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10332535">10332535</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:39279569">39279569</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Annals+of+Pharmacotherapy&rft.atitle=Domperidone%3A+a+peripherally+acting+dopamine2-receptor+antagonist&rft.volume=33&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E429-%3C%2Fspan%3E440&rft.date=1999-04&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A39279569%23id-name%3DS2CID&rft_id=info%3Apmid%2F10332535&rft_id=info%3Adoi%2F10.1345%2Faph.18003&rft.aulast=Barone&rft.aufirst=JA&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-ema-11"><span class="mw-cite-backlink">^ <a href="#cite_ref-ema_11-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-ema_11-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-ema_11-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation pressrelease cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/news/cmdh-confirms-recommendations-restricting-use-domperidone-containing-medicines">"CMDh confirms recommendations on restricting use of domperidone-containing medicines"</a> (Press release). <a href="/wiki/European_Medicines_Agency" title="European Medicines Agency">European Medicines Agency</a>. 25 April 2014. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20160130200137/http://www.ema.europa.eu/ema/index.jsp?curl=pages%2Fnews_and_events%2Fnews%2F2014%2F04%2Fnews_detail_002083.jsp">Archived</a> from the original on 30 January 2016<span class="reference-accessdate">. Retrieved <span class="nowrap">31 October</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=CMDh+confirms+recommendations+on+restricting+use+of+domperidone-containing+medicines&rft.pub=European+Medicines+Agency&rft.date=2014-04-25&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fen%2Fnews%2Fcmdh-confirms-recommendations-restricting-use-domperidone-containing-medicines&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-mhra-12"><span class="mw-cite-backlink">^ <a href="#cite_ref-mhra_12-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-mhra_12-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20141213170157/http://www.mhra.gov.uk/home/groups/par/documents/websiteresources/con076114.pdf">"Motilium INSTANTS PL 13249/0028"</a> <span class="cs1-format">(PDF)</span>. <a href="/wiki/Medicines_and_Healthcare_products_Regulatory_Agency" title="Medicines and Healthcare products Regulatory Agency">Medicines and Healthcare products Regulatory Agency</a>. 23 February 2010. Archived from <a rel="nofollow" class="external text" href="http://www.mhra.gov.uk/home/groups/par/documents/websiteresources/con076114.pdf">the original</a> <span class="cs1-format">(PDF)</span> on 13 December 2014<span class="reference-accessdate">. Retrieved <span class="nowrap">31 October</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Motilium+INSTANTS+PL+13249%2F0028&rft.pub=Medicines+and+Healthcare+products+Regulatory+Agency&rft.date=2010-02-23&rft_id=http%3A%2F%2Fwww.mhra.gov.uk%2Fhome%2Fgroups%2Fpar%2Fdocuments%2Fwebsiteresources%2Fcon076114.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-BNF79-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-BNF79_13-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation book cs1"><i>BNF 79 : March 2020</i>. London: Royal Pharmaceutical Society. 2020. p. 444. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780857113658" title="Special:BookSources/9780857113658"><bdi>9780857113658</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=BNF+79+%3A+March+2020.&rft.place=London&rft.pages=444&rft.pub=Royal+Pharmaceutical+Society&rft.date=2020&rft.isbn=9780857113658&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Henderson2003-14"><span class="mw-cite-backlink">^ <a href="#cite_ref-Henderson2003_14-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Henderson2003_14-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Henderson2003_14-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHenderson2003" class="citation journal cs1">Henderson A (2003). "Domperidone. Discovering new choices for lactating mothers". <i>AWHONN Lifelines</i>. <b>7</b> (1): <span class="nowrap">54–</span>60. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1177%2F1091592303251726">10.1177/1091592303251726</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12674062">12674062</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=AWHONN+Lifelines&rft.atitle=Domperidone.+Discovering+new+choices+for+lactating+mothers&rft.volume=7&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E54-%3C%2Fspan%3E60&rft.date=2003&rft_id=info%3Adoi%2F10.1177%2F1091592303251726&rft_id=info%3Apmid%2F12674062&rft.aulast=Henderson&rft.aufirst=A&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid26649742-15"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid26649742_15-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid26649742_15-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLeelakanokHolcombeSchweizer2016" class="citation journal cs1">Leelakanok N, Holcombe A, Schweizer ML (February 2016). "Domperidone and Risk of Ventricular Arrhythmia and Cardiac Death: A Systematic Review and Meta-analysis". <i>Clinical Drug Investigation</i>. <b>36</b> (2): <span class="nowrap">97–</span>107. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs40261-015-0360-0">10.1007/s40261-015-0360-0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26649742">26649742</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:25601738">25601738</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Drug+Investigation&rft.atitle=Domperidone+and+Risk+of+Ventricular+Arrhythmia+and+Cardiac+Death%3A+A+Systematic+Review+and+Meta-analysis&rft.volume=36&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E97-%3C%2Fspan%3E107&rft.date=2016-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A25601738%23id-name%3DS2CID&rft_id=info%3Apmid%2F26649742&rft_id=info%3Adoi%2F10.1007%2Fs40261-015-0360-0&rft.aulast=Leelakanok&rft.aufirst=N&rft.au=Holcombe%2C+A&rft.au=Schweizer%2C+ML&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid20394569-16"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid20394569_16-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid20394569_16-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRossiGiorgi2010" class="citation journal cs1">Rossi M, Giorgi G (July 2010). "Domperidone and long QT syndrome". <i>Current Drug Safety</i>. <b>5</b> (3): <span class="nowrap">257–</span>262. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2174%2F157488610791698334">10.2174/157488610791698334</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20394569">20394569</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Current+Drug+Safety&rft.atitle=Domperidone+and+long+QT+syndrome&rft.volume=5&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E257-%3C%2Fspan%3E262&rft.date=2010-07&rft_id=info%3Adoi%2F10.2174%2F157488610791698334&rft_id=info%3Apmid%2F20394569&rft.aulast=Rossi&rft.aufirst=M&rft.au=Giorgi%2C+G&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid24147629-17"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid24147629_17-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid24147629_17-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFDoggrellHancox2014" class="citation journal cs1">Doggrell SA, Hancox JC (January 2014). <a rel="nofollow" class="external text" href="https://eprints.qut.edu.au/65613/2/65613.pdf">"Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue medicine"</a> <span class="cs1-format">(PDF)</span>. <i>Expert Opinion on Drug Safety</i>. <b>13</b> (1): <span class="nowrap">131–</span>138. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1517%2F14740338.2014.851193">10.1517/14740338.2014.851193</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24147629">24147629</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:30668496">30668496</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Expert+Opinion+on+Drug+Safety&rft.atitle=Cardiac+safety+concerns+for+domperidone%2C+an+antiemetic+and+prokinetic%2C+and+galactogogue+medicine&rft.volume=13&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E131-%3C%2Fspan%3E138&rft.date=2014-01&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A30668496%23id-name%3DS2CID&rft_id=info%3Apmid%2F24147629&rft_id=info%3Adoi%2F10.1517%2F14740338.2014.851193&rft.aulast=Doggrell&rft.aufirst=SA&rft.au=Hancox%2C+JC&rft_id=https%3A%2F%2Feprints.qut.edu.au%2F65613%2F2%2F65613.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid26117678-18"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid26117678_18-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid26117678_18-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid26117678_18-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-pmid26117678_18-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBufferyStrother2015" class="citation journal cs1">Buffery PJ, Strother RM (June 2015). "Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations". <i>The New Zealand Medical Journal</i>. <b>128</b> (1416): <span class="nowrap">66–</span>74. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26117678">26117678</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+Zealand+Medical+Journal&rft.atitle=Domperidone+safety%3A+a+mini-review+of+the+science+of+QT+prolongation+and+clinical+implications+of+recent+global+regulatory+recommendations&rft.volume=128&rft.issue=1416&rft.pages=%3Cspan+class%3D%22nowrap%22%3E66-%3C%2Fspan%3E74&rft.date=2015-06&rft_id=info%3Apmid%2F26117678&rft.aulast=Buffery&rft.aufirst=PJ&rft.au=Strother%2C+RM&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-MarziWeitz2015-19"><span class="mw-cite-backlink">^ <a href="#cite_ref-MarziWeitz2015_19-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-MarziWeitz2015_19-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMarziWeitzAvilaMolina2015" class="citation journal cs1">Marzi M, Weitz D, Avila A, Molina G, Caraballo L, Piskulic L (January 2015). <a rel="nofollow" class="external text" href="https://doi.org/10.4067%2FS0034-98872015000100002">"[Cardiac adverse effects of domperidone in adult patients: a systematic review]"</a>. <i>Revista Médica de Chile</i>. <b>143</b> (1): <span class="nowrap">14–</span>21. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4067%2FS0034-98872015000100002">10.4067/S0034-98872015000100002</a></span>. <a href="/wiki/Hdl_(identifier)" class="mw-redirect" title="Hdl (identifier)">hdl</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://hdl.handle.net/2133%2F10526">2133/10526</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25860264">25860264</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Revista+M%C3%A9dica+de+Chile&rft.atitle=%5BCardiac+adverse+effects+of+domperidone+in+adult+patients%3A+a+systematic+review%5D&rft.volume=143&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E14-%3C%2Fspan%3E21&rft.date=2015-01&rft_id=info%3Ahdl%2F2133%2F10526&rft_id=info%3Apmid%2F25860264&rft_id=info%3Adoi%2F10.4067%2FS0034-98872015000100002&rft.aulast=Marzi&rft.aufirst=M&rft.au=Weitz%2C+D&rft.au=Avila%2C+A&rft.au=Molina%2C+G&rft.au=Caraballo%2C+L&rft.au=Piskulic%2C+L&rft_id=https%3A%2F%2Fdoi.org%2F10.4067%252FS0034-98872015000100002&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid25475074-20"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid25475074_20-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid25475074_20-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid25475074_20-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFPaulZénutDorutCoudoré2015" class="citation journal cs1">Paul C, Zénut M, Dorut A, Coudoré MA, Vein J, Cardot JM, et al. (February 2015). "Use of domperidone as a galactagogue drug: a systematic review of the benefit-risk ratio". <i>Journal of Human Lactation</i>. <b>31</b> (1): <span class="nowrap">57–</span>63. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1177%2F0890334414561265">10.1177/0890334414561265</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25475074">25475074</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:7978585">7978585</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Human+Lactation&rft.atitle=Use+of+domperidone+as+a+galactagogue+drug%3A+a+systematic+review+of+the+benefit-risk+ratio&rft.volume=31&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E57-%3C%2Fspan%3E63&rft.date=2015-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A7978585%23id-name%3DS2CID&rft_id=info%3Apmid%2F25475074&rft_id=info%3Adoi%2F10.1177%2F0890334414561265&rft.aulast=Paul&rft.aufirst=C&rft.au=Z%C3%A9nut%2C+M&rft.au=Dorut%2C+A&rft.au=Coudor%C3%A9%2C+MA&rft.au=Vein%2C+J&rft.au=Cardot%2C+JM&rft.au=Balayssac%2C+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid18507654-21"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid18507654_21-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid18507654_21-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid18507654_21-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWanDaveyPage-SharpHartmann2008" class="citation journal cs1">Wan EW, Davey K, Page-Sharp M, Hartmann PE, Simmer K, Ilett KF (August 2008). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492930">"Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk"</a>. <i>British Journal of Clinical Pharmacology</i>. <b>66</b> (2): <span class="nowrap">283–</span>289. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1365-2125.2008.03207.x">10.1111/j.1365-2125.2008.03207.x</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492930">2492930</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18507654">18507654</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Clinical+Pharmacology&rft.atitle=Dose-effect+study+of+domperidone+as+a+galactagogue+in+preterm+mothers+with+insufficient+milk+supply%2C+and+its+transfer+into+milk&rft.volume=66&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E283-%3C%2Fspan%3E289&rft.date=2008-08&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2492930%23id-name%3DPMC&rft_id=info%3Apmid%2F18507654&rft_id=info%3Adoi%2F10.1111%2Fj.1365-2125.2008.03207.x&rft.aulast=Wan&rft.aufirst=EW&rft.au=Davey%2C+K&rft.au=Page-Sharp%2C+M&rft.au=Hartmann%2C+PE&rft.au=Simmer%2C+K&rft.au=Ilett%2C+KF&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2492930&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-dd-22"><span class="mw-cite-backlink">^ <a href="#cite_ref-dd_22-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-dd_22-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-dd_22-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-dd_22-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-dd_22-4"><sup><i><b>e</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSneader2005" class="citation book cs1">Sneader W (2005). "Plant Product Analogues and Compounds Derived from Them". <i>Drug discovery : a history</i>. Chichester: John Wiley & Sons Ltd. p. 125. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-471-89979-2" title="Special:BookSources/978-0-471-89979-2"><bdi>978-0-471-89979-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Plant+Product+Analogues+and+Compounds+Derived+from+Them&rft.btitle=Drug+discovery+%3A+a+history&rft.place=Chichester&rft.pages=125&rft.pub=John+Wiley+%26+Sons+Ltd&rft.date=2005&rft.isbn=978-0-471-89979-2&rft.aulast=Sneader&rft.aufirst=W&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-WilliamAndrewPublishing2013-23"><span class="mw-cite-backlink">^ <a href="#cite_ref-WilliamAndrewPublishing2013_23-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-WilliamAndrewPublishing2013_23-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation book cs1"><a rel="nofollow" class="external text" href="https://books.google.com/books?id=_J2ti4EkYpkC&pg=PA1381">"Domperidone"</a>. <i>Pharmaceutical Manufacturing Encyclopedia, 3rd Edition (Vol. 1-4)</i>. William Andrew Publishing. 2013. p. 138. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780815518563" title="Special:BookSources/9780815518563"><bdi>9780815518563</bdi></a><span class="reference-accessdate">. Retrieved <span class="nowrap">12 December</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Domperidone&rft.btitle=Pharmaceutical+Manufacturing+Encyclopedia%2C+3rd+Edition+%28Vol.+1-4%29&rft.pages=138&rft.pub=William+Andrew+Publishing&rft.date=2013&rft.isbn=9780815518563&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D_J2ti4EkYpkC%26pg%3DPA1381&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-FaisVermiglio2015-24"><span class="mw-cite-backlink">^ <a href="#cite_ref-FaisVermiglio2015_24-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-FaisVermiglio2015_24-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFFaisVermiglioLaposataLockwood2015" class="citation journal cs1">Fais P, Vermiglio E, Laposata C, Lockwood R, Gottardo R, De Leo D (September 2015). "A case of sudden cardiac death following Domperidone self-medication". <i>Forensic Science International</i>. <b>254</b>: <span class="nowrap">e1 –</span> <span class="nowrap">e3</span>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.forsciint.2015.06.004">10.1016/j.forsciint.2015.06.004</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26119456">26119456</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Forensic+Science+International&rft.atitle=A+case+of+sudden+cardiac+death+following+Domperidone+self-medication&rft.volume=254&rft.pages=%3Cspan+class%3D%22nowrap%22%3Ee1+-%3C%2Fspan%3E+%3Cspan+class%3D%22nowrap%22%3Ee3%3C%2Fspan%3E&rft.date=2015-09&rft_id=info%3Adoi%2F10.1016%2Fj.forsciint.2015.06.004&rft_id=info%3Apmid%2F26119456&rft.aulast=Fais&rft.aufirst=P&rft.au=Vermiglio%2C+E&rft.au=Laposata%2C+C&rft.au=Lockwood%2C+R&rft.au=Gottardo%2C+R&rft.au=De+Leo%2C+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-FDA_20231212-25"><span class="mw-cite-backlink">^ <a href="#cite_ref-FDA_20231212_25-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-FDA_20231212_25-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-FDA_20231212_25-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-FDA_20231212_25-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-FDA_20231212_25-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-FDA_20231212_25-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-FDA_20231212_25-6"><sup><i><b>g</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.fda.gov/drugs/investigational-new-drug-ind-application/how-request-domperidone-expanded-access-use">"How to Request Domperidone for Expanded Access Use"</a>. <i>U.S. <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">Food and Drug Administration</a> (FDA)</i>. 12 December 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=U.S.+Food+and+Drug+Administration+%28FDA%29&rft.atitle=How+to+Request+Domperidone+for+Expanded+Access+Use&rft.date=2023-12-12&rft_id=https%3A%2F%2Fwww.fda.gov%2Fdrugs%2Finvestigational-new-drug-ind-application%2Fhow-request-domperidone-expanded-access-use&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid15451832-26"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid15451832_26-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid15451832_26-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFda_SilvaKnoppert2004" class="citation journal cs1">da Silva OP, Knoppert DC (September 2004). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517853">"Domperidone for lactating women"</a>. <i>CMAJ</i>. <b>171</b> (7): <span class="nowrap">725–</span>726. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1503%2Fcmaj.1041054">10.1503/cmaj.1041054</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517853">517853</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15451832">15451832</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=CMAJ&rft.atitle=Domperidone+for+lactating+women&rft.volume=171&rft.issue=7&rft.pages=%3Cspan+class%3D%22nowrap%22%3E725-%3C%2Fspan%3E726&rft.date=2004-09&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC517853%23id-name%3DPMC&rft_id=info%3Apmid%2F15451832&rft_id=info%3Adoi%2F10.1503%2Fcmaj.1041054&rft.aulast=da+Silva&rft.aufirst=OP&rft.au=Knoppert%2C+DC&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC517853&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-AdisInsight-Deudomperidone-27"><span class="mw-cite-backlink"><b><a href="#cite_ref-AdisInsight-Deudomperidone_27-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://adisinsight.springer.com/drugs/800050807">"Deudomperidone - CinRx Pharma - AdisInsight"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Deudomperidone+-+CinRx+Pharma+-+AdisInsight&rft_id=https%3A%2F%2Fadisinsight.springer.com%2Fdrugs%2F800050807&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid33471485-28"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid33471485_28-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHeckrothLuckettMoserParajuli2021" class="citation journal cs1">Heckroth M, Luckett RT, Moser C, Parajuli D, Abell TL (April 2021). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933092">"Nausea and Vomiting in 2021: A Comprehensive Update"</a>. <i>Journal of Clinical Gastroenterology</i>. <b>55</b> (4): <span class="nowrap">279–</span>299. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2FMCG.0000000000001485">10.1097/MCG.0000000000001485</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933092">7933092</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/33471485">33471485</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Gastroenterology&rft.atitle=Nausea+and+Vomiting+in+2021%3A+A+Comprehensive+Update&rft.volume=55&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E279-%3C%2Fspan%3E299&rft.date=2021-04&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC7933092%23id-name%3DPMC&rft_id=info%3Apmid%2F33471485&rft_id=info%3Adoi%2F10.1097%2FMCG.0000000000001485&rft.aulast=Heckroth&rft.aufirst=M&rft.au=Luckett%2C+RT&rft.au=Moser%2C+C&rft.au=Parajuli%2C+D&rft.au=Abell%2C+TL&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC7933092&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-WoMcCallumGonzalez2021-29"><span class="mw-cite-backlink"><b><a href="#cite_ref-WoMcCallumGonzalez2021_29-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWoMcCallumGonzalez2021" class="citation book cs1">Wo JM, McCallum RW, Gonzalez Z (2021). "Antiemetic therapy for gastroparesis". <i>Gastroparesis</i>. Elsevier. pp. <span class="nowrap">341–</span>359. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FB978-0-12-818586-5.00025-9">10.1016/B978-0-12-818586-5.00025-9</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780128185865" title="Special:BookSources/9780128185865"><bdi>9780128185865</bdi></a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:225132800">225132800</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Antiemetic+therapy+for+gastroparesis&rft.btitle=Gastroparesis&rft.pages=%3Cspan+class%3D%22nowrap%22%3E341-%3C%2Fspan%3E359&rft.pub=Elsevier&rft.date=2021&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A225132800%23id-name%3DS2CID&rft_id=info%3Adoi%2F10.1016%2FB978-0-12-818586-5.00025-9&rft.isbn=9780128185865&rft.aulast=Wo&rft.aufirst=JM&rft.au=McCallum%2C+RW&rft.au=Gonzalez%2C+Z&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-30"><span class="mw-cite-backlink"><b><a href="#cite_ref-30">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWorthingtonPringsheimGawelGladstone2013" class="citation journal cs1">Worthington I, Pringsheim T, Gawel MJ, Gladstone J, Cooper P, Dilli E, et al. (September 2013). <a rel="nofollow" class="external text" href="https://doi.org/10.1017%2FS0317167100118943">"Canadian Headache Society Guideline: acute drug therapy for migraine headache"</a>. <i>The Canadian Journal of Neurological Sciences. Le Journal Canadien des Sciences Neurologiques</i>. <b>40</b> (5 Suppl 3): <span class="nowrap">S1 –</span> <span class="nowrap">S80</span>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1017%2FS0317167100118943">10.1017/S0317167100118943</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23968886">23968886</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Canadian+Journal+of+Neurological+Sciences.+Le+Journal+Canadien+des+Sciences+Neurologiques&rft.atitle=Canadian+Headache+Society+Guideline%3A+acute+drug+therapy+for+migraine+headache&rft.volume=40&rft.issue=5+Suppl+3&rft.pages=%3Cspan+class%3D%22nowrap%22%3ES1+-%3C%2Fspan%3E+%3Cspan+class%3D%22nowrap%22%3ES80%3C%2Fspan%3E&rft.date=2013-09&rft_id=info%3Adoi%2F10.1017%2FS0317167100118943&rft_id=info%3Apmid%2F23968886&rft.aulast=Worthington&rft.aufirst=I&rft.au=Pringsheim%2C+T&rft.au=Gawel%2C+MJ&rft.au=Gladstone%2C+J&rft.au=Cooper%2C+P&rft.au=Dilli%2C+E&rft.au=Aube%2C+M&rft.au=Leroux%2C+E&rft.au=Becker%2C+WJ&rft_id=https%3A%2F%2Fdoi.org%2F10.1017%252FS0317167100118943&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-31"><span class="mw-cite-backlink"><b><a href="#cite_ref-31">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFStevensJonesRaynerHorowitz2013" class="citation journal cs1">Stevens JE, Jones KL, Rayner CK, Horowitz M (June 2013). "Pathophysiology and pharmacotherapy of gastroparesis: current and future perspectives". <i>Expert Opinion on Pharmacotherapy</i>. <b>14</b> (9): <span class="nowrap">1171–</span>1186. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1517%2F14656566.2013.795948">10.1517/14656566.2013.795948</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23663133">23663133</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23526883">23526883</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Expert+Opinion+on+Pharmacotherapy&rft.atitle=Pathophysiology+and+pharmacotherapy+of+gastroparesis%3A+current+and+future+perspectives&rft.volume=14&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1171-%3C%2Fspan%3E1186&rft.date=2013-06&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23526883%23id-name%3DS2CID&rft_id=info%3Apmid%2F23663133&rft_id=info%3Adoi%2F10.1517%2F14656566.2013.795948&rft.aulast=Stevens&rft.aufirst=JE&rft.au=Jones%2C+KL&rft.au=Rayner%2C+CK&rft.au=Horowitz%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid9663360-32"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9663360_32-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSilversKipnesBroadstonePatterson1998" class="citation journal cs1">Silvers D, Kipnes M, Broadstone V, Patterson D, Quigley EM, McCallum R, et al. (1998). "Domperidone in the management of symptoms of diabetic gastroparesis: efficacy, tolerability, and quality-of-life outcomes in a multicenter controlled trial. DOM-USA-5 Study Group". <i>Clinical Therapeutics</i>. <b>20</b> (3): <span class="nowrap">438–</span>453. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0149-2918%2898%2980054-4">10.1016/S0149-2918(98)80054-4</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9663360">9663360</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Therapeutics&rft.atitle=Domperidone+in+the+management+of+symptoms+of+diabetic+gastroparesis%3A+efficacy%2C+tolerability%2C+and+quality-of-life+outcomes+in+a+multicenter+controlled+trial.+DOM-USA-5+Study+Group&rft.volume=20&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E438-%3C%2Fspan%3E453&rft.date=1998&rft_id=info%3Adoi%2F10.1016%2FS0149-2918%2898%2980054-4&rft_id=info%3Apmid%2F9663360&rft.aulast=Silvers&rft.aufirst=D&rft.au=Kipnes%2C+M&rft.au=Broadstone%2C+V&rft.au=Patterson%2C+D&rft.au=Quigley%2C+EM&rft.au=McCallum%2C+R&rft.au=Leidy%2C+NK&rft.au=Farup%2C+C&rft.au=Liu%2C+Y&rft.au=Joslyn%2C+A&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-33"><span class="mw-cite-backlink"><b><a href="#cite_ref-33">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFJanssenHarrisJonesMasaoka2013" class="citation journal cs1">Janssen P, Harris MS, Jones M, Masaoka T, Farré R, Törnblom H, et al. (September 2013). "The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis". <i>The American Journal of Gastroenterology</i>. <b>108</b> (9): <span class="nowrap">1382–</span>1391. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fajg.2013.118">10.1038/ajg.2013.118</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24005344">24005344</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:32835351">32835351</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+American+Journal+of+Gastroenterology&rft.atitle=The+relation+between+symptom+improvement+and+gastric+emptying+in+the+treatment+of+diabetic+and+idiopathic+gastroparesis&rft.volume=108&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1382-%3C%2Fspan%3E1391&rft.date=2013-09&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A32835351%23id-name%3DS2CID&rft_id=info%3Apmid%2F24005344&rft_id=info%3Adoi%2F10.1038%2Fajg.2013.118&rft.aulast=Janssen&rft.aufirst=P&rft.au=Harris%2C+MS&rft.au=Jones%2C+M&rft.au=Masaoka%2C+T&rft.au=Farr%C3%A9%2C+R&rft.au=T%C3%B6rnblom%2C+H&rft.au=Van+Oudenhove%2C+L&rft.au=Simr%C3%A9n%2C+M&rft.au=Tack%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-FDADomperidone-34"><span class="mw-cite-backlink">^ <a href="#cite_ref-FDADomperidone_34-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-FDADomperidone_34-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-FDADomperidone_34-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.fda.gov/drugs/information-drug-class/information-about-domperidone">"Information about Domperidone"</a>. <i>U.S. <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">Food and Drug Administration</a> (FDA)</i>. 12 December 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">8 June</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=U.S.+Food+and+Drug+Administration+%28FDA%29&rft.atitle=Information+about+Domperidone&rft.date=2023-12-12&rft_id=https%3A%2F%2Fwww.fda.gov%2Fdrugs%2Finformation-drug-class%2Finformation-about-domperidone&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span> <span class="noviewer" typeof="mw:File"><span><img alt="Public Domain" src="//upload.wikimedia.org/wikipedia/en/thumb/6/62/PD-icon.svg/12px-PD-icon.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/6/62/PD-icon.svg/18px-PD-icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/6/62/PD-icon.svg/24px-PD-icon.svg.png 2x" data-file-width="196" data-file-height="196" /></span></span> This article incorporates text from this source, which is in the <a href="/wiki/Public_domain" title="Public domain">public domain</a>.</span> </li> <li id="cite_note-t992-35"><span class="mw-cite-backlink"><b><a href="#cite_ref-t992_35-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGrzeskowiakSmithersAmirGrivell2018" class="citation journal cs1">Grzeskowiak LE, Smithers LG, Amir LH, Grivell RM (October 2018). "Domperidone for increasing breast milk volume in mothers expressing breast milk for their preterm infants: a systematic review and meta-analysis". <i>BJOG</i>. <b>125</b> (11). Wiley: <span class="nowrap">1371–</span>1378. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2F1471-0528.15177">10.1111/1471-0528.15177</a>. <a href="/wiki/Hdl_(identifier)" class="mw-redirect" title="Hdl (identifier)">hdl</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://hdl.handle.net/2440%2F114203">2440/114203</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/29469929">29469929</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=BJOG&rft.atitle=Domperidone+for+increasing+breast+milk+volume+in+mothers+expressing+breast+milk+for+their+preterm+infants%3A+a+systematic+review+and+meta-analysis&rft.volume=125&rft.issue=11&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1371-%3C%2Fspan%3E1378&rft.date=2018-10&rft_id=info%3Ahdl%2F2440%2F114203&rft_id=info%3Apmid%2F29469929&rft_id=info%3Adoi%2F10.1111%2F1471-0528.15177&rft.aulast=Grzeskowiak&rft.aufirst=LE&rft.au=Smithers%2C+LG&rft.au=Amir%2C+LH&rft.au=Grivell%2C+RM&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-NIH-36"><span class="mw-cite-backlink"><b><a href="#cite_ref-NIH_36-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation journal cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK501371/">"Domperidone"</a>. <i>Drugs and Lactation Database</i>. Bethesda (MD): National Institute of Child Health and Human Development. 15 May 2024 [2006]. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/30000430">30000430</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Drugs+and+Lactation+Database&rft.atitle=Domperidone&rft.date=2024-05-15&rft_id=info%3Apmid%2F30000430&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fbooks%2FNBK501371%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-HealthCanada-37"><span class="mw-cite-backlink"><b><a href="#cite_ref-HealthCanada_37-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://dhpp.hpfb-dgpsa.ca/review-documents/resource/SSR1691692252806">"Assessing the Potential Risk of Psychiatric Withdrawal Events when Used for Lactation Stimulation"</a>. <i>Drug and Health Products Portal</i>. 8 June 2024<span class="reference-accessdate">. Retrieved <span class="nowrap">8 June</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Drug+and+Health+Products+Portal&rft.atitle=Assessing+the+Potential+Risk+of+Psychiatric+Withdrawal+Events+when+Used+for+Lactation+Stimulation&rft.date=2024-06-08&rft_id=https%3A%2F%2Fdhpp.hpfb-dgpsa.ca%2Freview-documents%2Fresource%2FSSR1691692252806&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-e088-38"><span class="mw-cite-backlink"><b><a href="#cite_ref-e088_38-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMorielloPatersonReynierDahl2021" class="citation journal cs1">Moriello C, Paterson JM, Reynier P, Dahl M, Aibibula W, Fisher A, et al. (2021). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157989">"Off-label postpartum use of domperidone in Canada: a multidatabase cohort study"</a>. <i>CMAJ Open</i>. <b>9</b> (2). CMA Joule Inc.: <span class="nowrap">E500 –</span> <span class="nowrap">E509</span>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.9778%2Fcmajo.20200084">10.9778/cmajo.20200084</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157989">8157989</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/33990364">33990364</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=CMAJ+Open&rft.atitle=Off-label+postpartum+use+of+domperidone+in+Canada%3A+a+multidatabase+cohort+study&rft.volume=9&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3EE500+-%3C%2Fspan%3E+%3Cspan+class%3D%22nowrap%22%3EE509%3C%2Fspan%3E&rft.date=2021&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC8157989%23id-name%3DPMC&rft_id=info%3Apmid%2F33990364&rft_id=info%3Adoi%2F10.9778%2Fcmajo.20200084&rft.aulast=Moriello&rft.aufirst=C&rft.au=Paterson%2C+JM&rft.au=Reynier%2C+P&rft.au=Dahl%2C+M&rft.au=Aibibula%2C+W&rft.au=Fisher%2C+A&rft.au=Gamble%2C+JM&rft.au=Kuo%2C+IF&rft.au=Ronksley%2C+PE&rft.au=Winquist%2C+B&rft.au=Filion%2C+KB&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC8157989&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid30361854-39"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid30361854_39-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRamprasadDouglasMoshiree2018" class="citation journal cs1">Ramprasad C, Douglas JY, Moshiree B (December 2018). "Parkinson's Disease and Current Treatments for Its Gastrointestinal Neurogastromotility Effects". <i>Current Treatment Options in Gastroenterology</i>. <b>16</b> (4): <span class="nowrap">489–</span>510. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs11938-018-0201-3">10.1007/s11938-018-0201-3</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/30361854">30361854</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:53104650">53104650</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Current+Treatment+Options+in+Gastroenterology&rft.atitle=Parkinson%27s+Disease+and+Current+Treatments+for+Its+Gastrointestinal+Neurogastromotility+Effects&rft.volume=16&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E489-%3C%2Fspan%3E510&rft.date=2018-12&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A53104650%23id-name%3DS2CID&rft_id=info%3Apmid%2F30361854&rft_id=info%3Adoi%2F10.1007%2Fs11938-018-0201-3&rft.aulast=Ramprasad&rft.aufirst=C&rft.au=Douglas%2C+JY&rft.au=Moshiree%2C+B&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid18281732-40"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid18281732_40-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLertxundiPeralMoraDomingo-Echaburu2008" class="citation journal cs1">Lertxundi U, Peral J, Mora O, Domingo-Echaburu S, Martínez-Bengoechea MJ, García-Moncó JC (March 2008). "Antidopaminergic therapy for managing comorbidities in patients with Parkinson's disease". <i>American Journal of Health-System Pharmacy</i>. <b>65</b> (5): <span class="nowrap">414–</span>419. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2146%2Fajhp060624">10.2146/ajhp060624</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18281732">18281732</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Health-System+Pharmacy&rft.atitle=Antidopaminergic+therapy+for+managing+comorbidities+in+patients+with+Parkinson%27s+disease&rft.volume=65&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E414-%3C%2Fspan%3E419&rft.date=2008-03&rft_id=info%3Adoi%2F10.2146%2Fajhp060624&rft_id=info%3Apmid%2F18281732&rft.aulast=Lertxundi&rft.aufirst=U&rft.au=Peral%2C+J&rft.au=Mora%2C+O&rft.au=Domingo-Echaburu%2C+S&rft.au=Mart%C3%ADnez-Bengoechea%2C+MJ&rft.au=Garc%C3%ADa-Monc%C3%B3%2C+JC&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid9108986-41"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9108986_41-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFJost1997" class="citation journal cs1">Jost WH (April 1997). "Gastrointestinal motility problems in patients with Parkinson's disease. Effects of antiparkinsonian treatment and guidelines for management". <i>Drugs & Aging</i>. <b>10</b> (4): <span class="nowrap">249–</span>258. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2165%2F00002512-199710040-00002">10.2165/00002512-199710040-00002</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9108986">9108986</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:38114001">38114001</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Drugs+%26+Aging&rft.atitle=Gastrointestinal+motility+problems+in+patients+with+Parkinson%27s+disease.+Effects+of+antiparkinsonian+treatment+and+guidelines+for+management&rft.volume=10&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E249-%3C%2Fspan%3E258&rft.date=1997-04&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A38114001%23id-name%3DS2CID&rft_id=info%3Apmid%2F9108986&rft_id=info%3Adoi%2F10.2165%2F00002512-199710040-00002&rft.aulast=Jost&rft.aufirst=WH&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-BacchiChimKramer2017-42"><span class="mw-cite-backlink"><b><a href="#cite_ref-BacchiChimKramer2017_42-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBacchiChimKramerPostuma2017" class="citation journal cs1">Bacchi S, Chim I, Kramer P, Postuma RB (2017). "Domperidone for Hypotension in Parkinson's Disease: A Systematic Review". <i>J Parkinsons Dis</i>. <b>7</b> (4): <span class="nowrap">603–</span>617. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3233%2FJPD-171209">10.3233/JPD-171209</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/29103053">29103053</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J+Parkinsons+Dis&rft.atitle=Domperidone+for+Hypotension+in+Parkinson%27s+Disease%3A+A+Systematic+Review&rft.volume=7&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E603-%3C%2Fspan%3E617&rft.date=2017&rft_id=info%3Adoi%2F10.3233%2FJPD-171209&rft_id=info%3Apmid%2F29103053&rft.aulast=Bacchi&rft.aufirst=S&rft.au=Chim%2C+I&rft.au=Kramer%2C+P&rft.au=Postuma%2C+RB&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-LiWuCui2023-43"><span class="mw-cite-backlink"><b><a href="#cite_ref-LiWuCui2023_43-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFPapakonstantinouNikolakopoulouHigginsEgger2020" class="citation journal cs1">Papakonstantinou T, Nikolakopoulou A, Higgins JP, Egger M, Salanti G (March 2020). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056828">"CINeMA: Software for semiautomated assessment of the confidence in the results of network meta-analysis"</a>. <i>Campbell Systematic Reviews</i>. <b>16</b> (1): e1080. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2F14651858.CD014883">10.1002/14651858.CD014883</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056828">10056828</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/37131978">37131978</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Campbell+Systematic+Reviews&rft.atitle=CINeMA%3A+Software+for+semiautomated+assessment+of+the+confidence+in+the+results+of+network+meta-analysis&rft.volume=16&rft.issue=1&rft.pages=e1080&rft.date=2020-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10056828%23id-name%3DPMC&rft_id=info%3Apmid%2F37131978&rft_id=info%3Adoi%2F10.1002%2F14651858.CD014883&rft.aulast=Papakonstantinou&rft.aufirst=T&rft.au=Nikolakopoulou%2C+A&rft.au=Higgins%2C+JP&rft.au=Egger%2C+M&rft.au=Salanti%2C+G&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10056828&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Lang2001-44"><span class="mw-cite-backlink"><b><a href="#cite_ref-Lang2001_44-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLang2001" class="citation journal cs1">Lang AE (May 2001). "Acute orthostatic hypotension when starting dopamine agonist therapy in parkinson disease: the role of domperidone therapy". <i>Arch Neurol</i>. <b>58</b> (5): 835. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1001%2Farchneur.58.5.835">10.1001/archneur.58.5.835</a> (inactive 11 November 2024). <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11346387">11346387</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Arch+Neurol&rft.atitle=Acute+orthostatic+hypotension+when+starting+dopamine+agonist+therapy+in+parkinson+disease%3A+the+role+of+domperidone+therapy&rft.volume=58&rft.issue=5&rft.pages=835&rft.date=2001-05&rft_id=info%3Adoi%2F10.1001%2Farchneur.58.5.835&rft_id=info%3Apmid%2F11346387&rft.aulast=Lang&rft.aufirst=AE&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: DOI inactive as of November 2024 (<a href="/wiki/Category:CS1_maint:_DOI_inactive_as_of_November_2024" title="Category:CS1 maint: DOI inactive as of November 2024">link</a>)</span></span> </li> <li id="cite_note-LuchsingerGrilliVelasco1998-45"><span class="mw-cite-backlink"><b><a href="#cite_ref-LuchsingerGrilliVelasco1998_45-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLuchsingerGrilliVelasco1998" class="citation journal cs1">Luchsinger A, Grilli M, Velasco M (March 1998). "Metoclopramide and domperidone block the antihypertensive effect of bromocriptine in hypertensive patients". <i>Am J Ther</i>. <b>5</b> (2): <span class="nowrap">81–</span>88. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F00045391-199803000-00005">10.1097/00045391-199803000-00005</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10099042">10099042</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Am+J+Ther&rft.atitle=Metoclopramide+and+domperidone+block+the+antihypertensive+effect+of+bromocriptine+in+hypertensive+patients&rft.volume=5&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E81-%3C%2Fspan%3E88&rft.date=1998-03&rft_id=info%3Adoi%2F10.1097%2F00045391-199803000-00005&rft_id=info%3Apmid%2F10099042&rft.aulast=Luchsinger&rft.aufirst=A&rft.au=Grilli%2C+M&rft.au=Velasco%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-SchofferHendersonOMaley2007-46"><span class="mw-cite-backlink"><b><a href="#cite_ref-SchofferHendersonOMaley2007_46-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSchofferHendersonO'MaleyO'Sullivan2007" class="citation journal cs1">Schoffer KL, Henderson RD, O'Maley K, O'Sullivan JD (August 2007). "Nonpharmacological treatment, fludrocortisone, and domperidone for orthostatic hypotension in Parkinson's disease". <i>Mov Disord</i>. <b>22</b> (11): <span class="nowrap">1543–</span>1549. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fmds.21428">10.1002/mds.21428</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17557339">17557339</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mov+Disord&rft.atitle=Nonpharmacological+treatment%2C+fludrocortisone%2C+and+domperidone+for+orthostatic+hypotension+in+Parkinson%27s+disease&rft.volume=22&rft.issue=11&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1543-%3C%2Fspan%3E1549&rft.date=2007-08&rft_id=info%3Adoi%2F10.1002%2Fmds.21428&rft_id=info%3Apmid%2F17557339&rft.aulast=Schoffer&rft.aufirst=KL&rft.au=Henderson%2C+RD&rft.au=O%27Maley%2C+K&rft.au=O%27Sullivan%2C+JD&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-47"><span class="mw-cite-backlink"><b><a href="#cite_ref-47">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFXiaoQiuYueCai2013" class="citation journal cs1">Xiao M, Qiu X, Yue D, Cai Y, Mo Q (2013). <a rel="nofollow" class="external text" href="https://www.nuclmed.gr/wp/wp-content/uploads/2017/03/42-4.pdf">"Influence of hippophae rhamnoides on two appetite factors, gastric emptying and metabolic parameters, in children with functional dyspepsia"</a> <span class="cs1-format">(PDF)</span>. <i>Hellenic Journal of Nuclear Medicine</i>. <b>16</b> (1): <span class="nowrap">38–</span>43. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23529392">23529392</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Hellenic+Journal+of+Nuclear+Medicine&rft.atitle=Influence+of+hippophae+rhamnoides+on+two+appetite+factors%2C+gastric+emptying+and+metabolic+parameters%2C+in+children+with+functional+dyspepsia&rft.volume=16&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E38-%3C%2Fspan%3E43&rft.date=2013&rft_id=info%3Apmid%2F23529392&rft.aulast=Xiao&rft.aufirst=M&rft.au=Qiu%2C+X&rft.au=Yue%2C+D&rft.au=Cai%2C+Y&rft.au=Mo%2C+Q&rft_id=https%3A%2F%2Fwww.nuclmed.gr%2Fwp%2Fwp-content%2Fuploads%2F2017%2F03%2F42-4.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-48"><span class="mw-cite-backlink"><b><a href="#cite_ref-48">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHuangLvZhangFan2012" class="citation journal cs1">Huang X, Lv B, Zhang S, Fan YH, Meng LN (December 2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544044">"Itopride therapy for functional dyspepsia: a meta-analysis"</a>. <i>World Journal of Gastroenterology</i>. <b>18</b> (48): <span class="nowrap">7371–</span>7377. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.3748%2Fwjg.v18.i48.7371">10.3748/wjg.v18.i48.7371</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544044">3544044</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23326147">23326147</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=World+Journal+of+Gastroenterology&rft.atitle=Itopride+therapy+for+functional+dyspepsia%3A+a+meta-analysis&rft.volume=18&rft.issue=48&rft.pages=%3Cspan+class%3D%22nowrap%22%3E7371-%3C%2Fspan%3E7377&rft.date=2012-12&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3544044%23id-name%3DPMC&rft_id=info%3Apmid%2F23326147&rft_id=info%3Adoi%2F10.3748%2Fwjg.v18.i48.7371&rft.aulast=Huang&rft.aufirst=X&rft.au=Lv%2C+B&rft.au=Zhang%2C+S&rft.au=Fan%2C+YH&rft.au=Meng%2C+LN&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3544044&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-49"><span class="mw-cite-backlink"><b><a href="#cite_ref-49">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFKapoorRaju2013" class="citation book cs1">Kapoor AK, Raju SM (2013). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=Le28AQAAQBAJ&pg=PA677">"7.2 Gastrointestinal Drugs"</a>. <i>Illustrated Medical Pharmacology</i>. JP Medical Ltd. p. 677. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-9350906552" title="Special:BookSources/978-9350906552"><bdi>978-9350906552</bdi></a><span class="reference-accessdate">. Retrieved <span class="nowrap">31 October</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=7.2+Gastrointestinal+Drugs&rft.btitle=Illustrated+Medical+Pharmacology&rft.pages=677&rft.pub=JP+Medical+Ltd&rft.date=2013&rft.isbn=978-9350906552&rft.aulast=Kapoor&rft.aufirst=AK&rft.au=Raju%2C+SM&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DLe28AQAAQBAJ%26pg%3DPA677&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span> (Google Books)</span> </li> <li id="cite_note-50"><span class="mw-cite-backlink"><b><a href="#cite_ref-50">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSmith2014" class="citation news cs1">Smith R (1 August 2014). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20141005121124/http://www.telegraph.co.uk/health/healthnews/11005559/Fear-that-reflux-treatment-for-babies-will-be-denied-under-new-Nice-guidance.html">"Fear that reflux treatment for babies will be denied under new Nice guidance"</a>. <a href="/wiki/The_Daily_Telegraph" title="The Daily Telegraph">The Daily Telegraph</a>. Archived from <a rel="nofollow" class="external text" href="https://www.telegraph.co.uk/health/healthnews/11005559/Fear-that-reflux-treatment-for-babies-will-be-denied-under-new-Nice-guidance.html">the original</a> on 5 October 2014<span class="reference-accessdate">. Retrieved <span class="nowrap">31 October</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Fear+that+reflux+treatment+for+babies+will+be+denied+under+new+Nice+guidance&rft.date=2014-08-01&rft.aulast=Smith&rft.aufirst=R&rft_id=https%3A%2F%2Fwww.telegraph.co.uk%2Fhealth%2Fhealthnews%2F11005559%2FFear-that-reflux-treatment-for-babies-will-be-denied-under-new-Nice-guidance.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-51"><span class="mw-cite-backlink"><b><a href="#cite_ref-51">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTraviMiró2018" class="citation journal cs1">Travi BL, Miró G (October 2018). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193371">"Use of domperidone in canine visceral leishmaniasis: gaps in veterinary knowledge and epidemiological implications"</a>. <i>Memórias do Instituto Oswaldo Cruz</i>. <b>113</b> (11): e180301. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1590%2F0074-02760180301">10.1590/0074-02760180301</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193371">6193371</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/30365645">30365645</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mem%C3%B3rias+do+Instituto+Oswaldo+Cruz&rft.atitle=Use+of+domperidone+in+canine+visceral+leishmaniasis%3A+gaps+in+veterinary+knowledge+and+epidemiological+implications&rft.volume=113&rft.issue=11&rft.pages=e180301&rft.date=2018-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6193371%23id-name%3DPMC&rft_id=info%3Apmid%2F30365645&rft_id=info%3Adoi%2F10.1590%2F0074-02760180301&rft.aulast=Travi&rft.aufirst=BL&rft.au=Mir%C3%B3%2C+G&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6193371&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-52"><span class="mw-cite-backlink"><b><a href="#cite_ref-52">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=e55d075e-2fe2-4405-b57a-59b85067e0c0">"EQUIDONE® Gel (domperidone)"</a>. <i>dailymed.nlm.nih.gov</i><span class="reference-accessdate">. Retrieved <span class="nowrap">25 October</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=dailymed.nlm.nih.gov&rft.atitle=EQUIDONE%C2%AE+Gel+%28domperidone%29&rft_id=https%3A%2F%2Fdailymed.nlm.nih.gov%2Fdailymed%2Ffda%2FfdaDrugXsl.cfm%3Fsetid%3De55d075e-2fe2-4405-b57a-59b85067e0c0&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-MIMS-53"><span class="mw-cite-backlink">^ <a href="#cite_ref-MIMS_53-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-MIMS_53-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text">Swannick G. (ed.) "MIMS Australia." December 2013</span> </li> <li id="cite_note-pmid24660005-54"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid24660005_54-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFFerrier2014" class="citation journal cs1">Ferrier J (March 2014). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962062">"Domperidone as an unintended antipsychotic"</a>. <i>Canadian Pharmacists Journal</i>. <b>147</b> (2): <span class="nowrap">76–</span>77. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1177%2F1715163514521969">10.1177/1715163514521969</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962062">3962062</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24660005">24660005</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Canadian+Pharmacists+Journal&rft.atitle=Domperidone+as+an+unintended+antipsychotic&rft.volume=147&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E76-%3C%2Fspan%3E77&rft.date=2014-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3962062%23id-name%3DPMC&rft_id=info%3Apmid%2F24660005&rft_id=info%3Adoi%2F10.1177%2F1715163514521969&rft.aulast=Ferrier&rft.aufirst=J&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3962062&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-JoslinKahn2005-55"><span class="mw-cite-backlink">^ <a href="#cite_ref-JoslinKahn2005_55-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-JoslinKahn2005_55-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFProctorKahn2005" class="citation book cs1">Proctor EJ, <a href="/wiki/C._Ronald_Kahn" title="C. Ronald Kahn">Kahn CR</a> (2005). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=ohgjG0qAvfgC&pg=PA1084"><i>Joslin's Diabetes Mellitus: Edited by C. Ronald Kahn ... [et Al.]</i></a>. Lippincott Williams & Wilkins. pp. 1084–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-7817-2796-9" title="Special:BookSources/978-0-7817-2796-9"><bdi>978-0-7817-2796-9</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Joslin%27s+Diabetes+Mellitus%3A+Edited+by+C.+Ronald+Kahn+...+%26%2391%3Bet+Al.%26%2393%3B&rft.pages=1084-&rft.pub=Lippincott+Williams+%26+Wilkins&rft.date=2005&rft.isbn=978-0-7817-2796-9&rft.aulast=Proctor&rft.aufirst=EJ&rft.au=Kahn%2C+CR&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DohgjG0qAvfgC%26pg%3DPA1084&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Jr.2010-56"><span class="mw-cite-backlink">^ <a href="#cite_ref-Jr.2010_56-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Jr.2010_56-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSabanegh_Jr2010" class="citation book cs1">Sabanegh Jr ES (20 October 2010). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=YthJpK5clTMC&pg=PA83"><i>Male Infertility: Problems and Solutions</i></a>. Springer Science & Business Media. pp. 83–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-60761-193-6" title="Special:BookSources/978-1-60761-193-6"><bdi>978-1-60761-193-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Male+Infertility%3A+Problems+and+Solutions&rft.pages=83-&rft.pub=Springer+Science+%26+Business+Media&rft.date=2010-10-20&rft.isbn=978-1-60761-193-6&rft.aulast=Sabanegh+Jr&rft.aufirst=ES&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DYthJpK5clTMC%26pg%3DPA83&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-BriggsFreeman2012-57"><span class="mw-cite-backlink"><b><a href="#cite_ref-BriggsFreeman2012_57-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBriggsFreemanYaffe2012" class="citation book cs1">Briggs GG, Freeman RK, Yaffe SJ (28 March 2012). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=ScPvM03B3lUC&pg=PA442"><i>Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk</i></a>. Lippincott Williams & Wilkins. pp. 442–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4511-5359-0" title="Special:BookSources/978-1-4511-5359-0"><bdi>978-1-4511-5359-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Drugs+in+Pregnancy+and+Lactation%3A+A+Reference+Guide+to+Fetal+and+Neonatal+Risk&rft.pages=442-&rft.pub=Lippincott+Williams+%26+Wilkins&rft.date=2012-03-28&rft.isbn=978-1-4511-5359-0&rft.aulast=Briggs&rft.aufirst=GG&rft.au=Freeman%2C+RK&rft.au=Yaffe%2C+SJ&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DScPvM03B3lUC%26pg%3DPA442&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid20455888-58"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid20455888_58-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHoltPeveler2011" class="citation journal cs1">Holt RI, Peveler RC (February 2011). "Antipsychotics and hyperprolactinaemia: mechanisms, consequences and management". <i>Clinical Endocrinology</i>. <b>74</b> (2): <span class="nowrap">141–</span>147. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1365-2265.2010.03814.x">10.1111/j.1365-2265.2010.03814.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20455888">20455888</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21617834">21617834</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Endocrinology&rft.atitle=Antipsychotics+and+hyperprolactinaemia%3A+mechanisms%2C+consequences+and+management&rft.volume=74&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E141-%3C%2Fspan%3E147&rft.date=2011-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21617834%23id-name%3DS2CID&rft_id=info%3Apmid%2F20455888&rft_id=info%3Adoi%2F10.1111%2Fj.1365-2265.2010.03814.x&rft.aulast=Holt&rft.aufirst=RI&rft.au=Peveler%2C+RC&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid20592331-59"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid20592331_59-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBusheBradleyPendlebury2010" class="citation journal cs1">Bushe CJ, Bradley A, Pendlebury J (July 2010). "A review of hyperprolactinaemia and severe mental illness: are there implications for clinical biochemistry?". <i>Annals of Clinical Biochemistry</i>. <b>47</b> (Pt 4): <span class="nowrap">292–</span>300. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1258%2Facb.2010.010025">10.1258/acb.2010.010025</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20592331">20592331</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21948581">21948581</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Annals+of+Clinical+Biochemistry&rft.atitle=A+review+of+hyperprolactinaemia+and+severe+mental+illness%3A+are+there+implications+for+clinical+biochemistry%3F&rft.volume=47&rft.issue=Pt+4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E292-%3C%2Fspan%3E300&rft.date=2010-07&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21948581%23id-name%3DS2CID&rft_id=info%3Apmid%2F20592331&rft_id=info%3Adoi%2F10.1258%2Facb.2010.010025&rft.aulast=Bushe&rft.aufirst=CJ&rft.au=Bradley%2C+A&rft.au=Pendlebury%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid30531551-60"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid30531551_60-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLertxundiErezumaHernandezMedrano2019" class="citation journal cs1">Lertxundi U, Erezuma I, Hernandez R, Medrano J, Garcia M, Aguirre C (March 2019). "Antipsychotics and pituitary tumors: an analysis of the European pharmacovigilance database (EudraVigilance)". <i>International Clinical Psychopharmacology</i>. <b>34</b> (2): <span class="nowrap">89–</span>92. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2FYIC.0000000000000247">10.1097/YIC.0000000000000247</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/30531551">30531551</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:54476916">54476916</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=International+Clinical+Psychopharmacology&rft.atitle=Antipsychotics+and+pituitary+tumors%3A+an+analysis+of+the+European+pharmacovigilance+database+%28EudraVigilance%29&rft.volume=34&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E89-%3C%2Fspan%3E92&rft.date=2019-03&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A54476916%23id-name%3DS2CID&rft_id=info%3Apmid%2F30531551&rft_id=info%3Adoi%2F10.1097%2FYIC.0000000000000247&rft.aulast=Lertxundi&rft.aufirst=U&rft.au=Erezuma%2C+I&rft.au=Hernandez%2C+R&rft.au=Medrano%2C+J&rft.au=Garcia%2C+M&rft.au=Aguirre%2C+C&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-DurraniVasireddyArshad2023-61"><span class="mw-cite-backlink"><b><a href="#cite_ref-DurraniVasireddyArshad2023_61-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFDurraniVasireddyArshadParacha2023" class="citation journal cs1">Durrani US, Vasireddy S, Arshad MZ, Paracha A, Paracha MA, Waheed F, et al. (November 2023). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10748855">"The Effect of Antipsychotics on Prolactinoma Growth: A Radiological and Serological Analysis"</a>. <i>Cureus</i>. <b>15</b> (11): e49342. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.7759%2Fcureus.49342">10.7759/cureus.49342</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10748855">10748855</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/38143631">38143631</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cureus&rft.atitle=The+Effect+of+Antipsychotics+on+Prolactinoma+Growth%3A+A+Radiological+and+Serological+Analysis&rft.volume=15&rft.issue=11&rft.pages=e49342&rft.date=2023-11&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10748855%23id-name%3DPMC&rft_id=info%3Apmid%2F38143631&rft_id=info%3Adoi%2F10.7759%2Fcureus.49342&rft.aulast=Durrani&rft.aufirst=US&rft.au=Vasireddy%2C+S&rft.au=Arshad%2C+MZ&rft.au=Paracha%2C+A&rft.au=Paracha%2C+MA&rft.au=Waheed%2C+F&rft.au=Abid%2C+A&rft.au=Siddiqui%2C+Z&rft.au=Thomure%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10748855&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-62"><span class="mw-cite-backlink"><b><a href="#cite_ref-62">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFvan_NoordDielemanvan_HerpenVerhamme2010" class="citation journal cs1">van Noord C, Dieleman JP, van Herpen G, Verhamme K, Sturkenboom MC (November 2010). "Domperidone and ventricular arrhythmia or sudden cardiac death: a population-based case-control study in the Netherlands". <i>Drug Safety</i>. <b>33</b> (11): <span class="nowrap">1003–</span>1014. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2165%2F11536840-000000000-00000">10.2165/11536840-000000000-00000</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20925438">20925438</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21177240">21177240</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Drug+Safety&rft.atitle=Domperidone+and+ventricular+arrhythmia+or+sudden+cardiac+death%3A+a+population-based+case-control+study+in+the+Netherlands&rft.volume=33&rft.issue=11&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1003-%3C%2Fspan%3E1014&rft.date=2010-11&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21177240%23id-name%3DS2CID&rft_id=info%3Apmid%2F20925438&rft_id=info%3Adoi%2F10.2165%2F11536840-000000000-00000&rft.aulast=van+Noord&rft.aufirst=C&rft.au=Dieleman%2C+JP&rft.au=van+Herpen%2C+G&rft.au=Verhamme%2C+K&rft.au=Sturkenboom%2C+MC&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-63"><span class="mw-cite-backlink"><b><a href="#cite_ref-63">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFJohannesVaras-LorenzoMcQuayMidkiff2010" class="citation journal cs1">Johannes CB, Varas-Lorenzo C, McQuay LJ, Midkiff KD, Fife D (September 2010). <a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fpds.2016">"Risk of serious ventricular arrhythmia and sudden cardiac death in a cohort of users of domperidone: a nested case-control study"</a>. <i>Pharmacoepidemiology and Drug Safety</i>. <b>19</b> (9): <span class="nowrap">881–</span>888. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fpds.2016">10.1002/pds.2016</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20652862">20652862</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:20323199">20323199</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Pharmacoepidemiology+and+Drug+Safety&rft.atitle=Risk+of+serious+ventricular+arrhythmia+and+sudden+cardiac+death+in+a+cohort+of+users+of+domperidone%3A+a+nested+case-control+study&rft.volume=19&rft.issue=9&rft.pages=%3Cspan+class%3D%22nowrap%22%3E881-%3C%2Fspan%3E888&rft.date=2010-09&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A20323199%23id-name%3DS2CID&rft_id=info%3Apmid%2F20652862&rft_id=info%3Adoi%2F10.1002%2Fpds.2016&rft.aulast=Johannes&rft.aufirst=CB&rft.au=Varas-Lorenzo%2C+C&rft.au=McQuay%2C+LJ&rft.au=Midkiff%2C+KD&rft.au=Fife%2C+D&rft_id=https%3A%2F%2Fdoi.org%2F10.1002%252Fpds.2016&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-OrtizCooper2015-64"><span class="mw-cite-backlink"><b><a href="#cite_ref-OrtizCooper2015_64-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFOrtizCooperAlvarezGomez2015" class="citation journal cs1">Ortiz A, Cooper CJ, Alvarez A, Gomez Y, Sarosiek I, McCallum RW (May 2015). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418779">"Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting"</a>. <i>The American Journal of the Medical Sciences</i>. <b>349</b> (5): <span class="nowrap">421–</span>424. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2FMAJ.0000000000000439">10.1097/MAJ.0000000000000439</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418779">4418779</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25828198">25828198</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+American+Journal+of+the+Medical+Sciences&rft.atitle=Cardiovascular+safety+profile+and+clinical+experience+with+high-dose+domperidone+therapy+for+nausea+and+vomiting&rft.volume=349&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E421-%3C%2Fspan%3E424&rft.date=2015-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4418779%23id-name%3DPMC&rft_id=info%3Apmid%2F25828198&rft_id=info%3Adoi%2F10.1097%2FMAJ.0000000000000439&rft.aulast=Ortiz&rft.aufirst=A&rft.au=Cooper%2C+CJ&rft.au=Alvarez%2C+A&rft.au=Gomez%2C+Y&rft.au=Sarosiek%2C+I&rft.au=McCallum%2C+RW&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4418779&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-65"><span class="mw-cite-backlink"><b><a href="#cite_ref-65">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFDjeddiKongoloLefaixMounard2008" class="citation journal cs1">Djeddi D, Kongolo G, Lefaix C, Mounard J, Léké A (November 2008). "Effect of domperidone on QT interval in neonates". <i>The Journal of Pediatrics</i>. <b>153</b> (5): <span class="nowrap">663–</span>666. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.jpeds.2008.05.013">10.1016/j.jpeds.2008.05.013</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18589449">18589449</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Pediatrics&rft.atitle=Effect+of+domperidone+on+QT+interval+in+neonates&rft.volume=153&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E663-%3C%2Fspan%3E666&rft.date=2008-11&rft_id=info%3Adoi%2F10.1016%2Fj.jpeds.2008.05.013&rft_id=info%3Apmid%2F18589449&rft.aulast=Djeddi&rft.aufirst=D&rft.au=Kongolo%2C+G&rft.au=Lefaix%2C+C&rft.au=Mounard%2C+J&rft.au=L%C3%A9k%C3%A9%2C+A&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-66"><span class="mw-cite-backlink"><b><a href="#cite_ref-66">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGünlemezBabaoğluArisoyTürker2010" class="citation journal cs1">Günlemez A, Babaoğlu A, Arisoy AE, Türker G, Gökalp AS (January 2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834362">"Effect of domperidone on the QTc interval in premature infants"</a>. <i>Journal of Perinatology</i>. <b>30</b> (1): <span class="nowrap">50–</span>53. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fjp.2009.96">10.1038/jp.2009.96</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834362">2834362</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19626027">19626027</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Perinatology&rft.atitle=Effect+of+domperidone+on+the+QTc+interval+in+premature+infants&rft.volume=30&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E50-%3C%2Fspan%3E53&rft.date=2010-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2834362%23id-name%3DPMC&rft_id=info%3Apmid%2F19626027&rft_id=info%3Adoi%2F10.1038%2Fjp.2009.96&rft.aulast=G%C3%BCnlemez&rft.aufirst=A&rft.au=Babao%C4%9Flu%2C+A&rft.au=Arisoy%2C+AE&rft.au=T%C3%BCrker%2C+G&rft.au=G%C3%B6kalp%2C+AS&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2834362&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-MHRA2014-67"><span class="mw-cite-backlink"><b><a href="#cite_ref-MHRA2014_67-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CON418518">"Domperidone: Risks of cardiac side effects"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Domperidone%3A+Risks+of+cardiac+side+effects&rft_id=http%3A%2F%2Fwww.mhra.gov.uk%2FSafetyinformation%2FDrugSafetyUpdate%2FCON418518&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-68"><span class="mw-cite-backlink"><b><a href="#cite_ref-68">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCoulthardHaycock2003" class="citation journal cs1">Coulthard MG, Haycock GB (January 2003). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1128889">"Distinguishing between salt poisoning and hypernatraemic dehydration in children"</a>. <i>BMJ</i>. <b>326</b> (7381): <span class="nowrap">157–</span>160. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1136%2Fbmj.326.7381.157">10.1136/bmj.326.7381.157</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1128889">1128889</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12531853">12531853</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=BMJ&rft.atitle=Distinguishing+between+salt+poisoning+and+hypernatraemic+dehydration+in+children&rft.volume=326&rft.issue=7381&rft.pages=%3Cspan+class%3D%22nowrap%22%3E157-%3C%2Fspan%3E160&rft.date=2003-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1128889%23id-name%3DPMC&rft_id=info%3Apmid%2F12531853&rft_id=info%3Adoi%2F10.1136%2Fbmj.326.7381.157&rft.aulast=Coulthard&rft.aufirst=MG&rft.au=Haycock%2C+GB&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1128889&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Aronson2009-69"><span class="mw-cite-backlink">^ <a href="#cite_ref-Aronson2009_69-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Aronson2009_69-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Aronson2009_69-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFAronson2009" class="citation book cs1">Aronson JK (27 November 2009). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=Zu2s5QBqiEkC&pg=PT2244"><i>Meyler's Side Effects of Antimicrobial Drugs</i></a>. Elsevier. pp. 2244–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-08-093293-4" title="Special:BookSources/978-0-08-093293-4"><bdi>978-0-08-093293-4</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Meyler%27s+Side+Effects+of+Antimicrobial+Drugs&rft.pages=2244-&rft.pub=Elsevier&rft.date=2009-11-27&rft.isbn=978-0-08-093293-4&rft.aulast=Aronson&rft.aufirst=JK&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DZu2s5QBqiEkC%26pg%3DPT2244&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-70"><span class="mw-cite-backlink"><b><a href="#cite_ref-70">^</a></b></span> <span class="reference-text">Saeb-Parsy K. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=F4-IdTewurIC">"Instant pharmacology."</a> John Wiley & Sons, 1999 <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0471976393" title="Special:BookSources/0471976393">0471976393</a>, 9780471976394 p216.</span> </li> <li id="cite_note-71"><span class="mw-cite-backlink"><b><a href="#cite_ref-71">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSakamotoKatoSekinoSakai2011" class="citation journal cs1">Sakamoto Y, Kato S, Sekino Y, Sakai E, Uchiyama T, Iida H, et al. (2011). "Effects of domperidone on gastric emptying: a crossover study using a continuous real-time 13C breath test (BreathID system)". <i>Hepato-Gastroenterology</i>. <b>58</b> (106): <span class="nowrap">637–</span>641. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21661445">21661445</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Hepato-Gastroenterology&rft.atitle=Effects+of+domperidone+on+gastric+emptying%3A+a+crossover+study+using+a+continuous+real-time+13C+breath+test+%28BreathID+system%29&rft.volume=58&rft.issue=106&rft.pages=%3Cspan+class%3D%22nowrap%22%3E637-%3C%2Fspan%3E641&rft.date=2011&rft_id=info%3Apmid%2F21661445&rft.aulast=Sakamoto&rft.aufirst=Y&rft.au=Kato%2C+S&rft.au=Sekino%2C+Y&rft.au=Sakai%2C+E&rft.au=Uchiyama%2C+T&rft.au=Iida%2C+H&rft.au=Hosono%2C+K&rft.au=Endo%2C+H&rft.au=Fujita%2C+K&rft.au=Koide%2C+T&rft.au=Takahashi%2C+H&rft.au=Yoneda%2C+M&rft.au=Tokoro%2C+C&rft.au=Goto%2C+A&rft.au=Abe%2C+Y&rft.au=Kobayashi%2C+N&rft.au=Kubota%2C+K&rft.au=Maeda%2C+S&rft.au=Nakajima%2C+A&rft.au=Inamori%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-72"><span class="mw-cite-backlink"><b><a href="#cite_ref-72">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFParkmanJacobsMishraHurdle2011" class="citation journal cs1">Parkman HP, Jacobs MR, Mishra A, Hurdle JA, Sachdeva P, Gaughan JP, et al. (January 2011). "Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects". <i>Digestive Diseases and Sciences</i>. <b>56</b> (1): <span class="nowrap">115–</span>124. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs10620-010-1472-2">10.1007/s10620-010-1472-2</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21063774">21063774</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:39632855">39632855</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Digestive+Diseases+and+Sciences&rft.atitle=Domperidone+treatment+for+gastroparesis%3A+demographic+and+pharmacogenetic+characterization+of+clinical+efficacy+and+side-effects&rft.volume=56&rft.issue=1&rft.pages=%3Cspan+class%3D%22nowrap%22%3E115-%3C%2Fspan%3E124&rft.date=2011-01&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A39632855%23id-name%3DS2CID&rft_id=info%3Apmid%2F21063774&rft_id=info%3Adoi%2F10.1007%2Fs10620-010-1472-2&rft.aulast=Parkman&rft.aufirst=HP&rft.au=Jacobs%2C+MR&rft.au=Mishra%2C+A&rft.au=Hurdle%2C+JA&rft.au=Sachdeva%2C+P&rft.au=Gaughan%2C+JP&rft.au=Krynetskiy%2C+E&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid12192964-73"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12192964_73-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGabay2002" class="citation journal cs1">Gabay MP (August 2002). "Galactogogues: medications that induce lactation". <i>Journal of Human Lactation</i>. <b>18</b> (3): <span class="nowrap">274–</span>279. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1177%2F089033440201800311">10.1177/089033440201800311</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12192964">12192964</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:29261467">29261467</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Human+Lactation&rft.atitle=Galactogogues%3A+medications+that+induce+lactation&rft.volume=18&rft.issue=3&rft.pages=%3Cspan+class%3D%22nowrap%22%3E274-%3C%2Fspan%3E279&rft.date=2002-08&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A29261467%23id-name%3DS2CID&rft_id=info%3Apmid%2F12192964&rft_id=info%3Adoi%2F10.1177%2F089033440201800311&rft.aulast=Gabay&rft.aufirst=MP&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid3882143-74"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid3882143_74-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid3882143_74-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid3882143_74-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-pmid3882143_74-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHofmeyrVan_IddekingeBlott1985" class="citation journal cs1">Hofmeyr GJ, Van Iddekinge B, Blott JA (February 1985). "Domperidone: secretion in breast milk and effect on puerperal prolactin levels". <i>British Journal of Obstetrics and Gynaecology</i>. <b>92</b> (2): <span class="nowrap">141–</span>144. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1471-0528.1985.tb01065.x">10.1111/j.1471-0528.1985.tb01065.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3882143">3882143</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:25489895">25489895</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Obstetrics+and+Gynaecology&rft.atitle=Domperidone%3A+secretion+in+breast+milk+and+effect+on+puerperal+prolactin+levels&rft.volume=92&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E141-%3C%2Fspan%3E144&rft.date=1985-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A25489895%23id-name%3DS2CID&rft_id=info%3Apmid%2F3882143&rft_id=info%3Adoi%2F10.1111%2Fj.1471-0528.1985.tb01065.x&rft.aulast=Hofmeyr&rft.aufirst=GJ&rft.au=Van+Iddekinge%2C+B&rft.au=Blott%2C+JA&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid7428183-75"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid7428183_75-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid7428183_75-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid7428183_75-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-pmid7428183_75-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-pmid7428183_75-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-pmid7428183_75-5"><sup><i><b>f</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBrouwersAssiesWiersingaHuizing1980" class="citation journal cs1">Brouwers JR, Assies J, Wiersinga WM, Huizing G, Tytgat GN (May 1980). "Plasma prolactin levels after acute and subchronic oral administration of domperidone and of metoclopramide: a cross-over study in healthy volunteers". <i>Clinical Endocrinology</i>. <b>12</b> (5): <span class="nowrap">435–</span>440. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1365-2265.1980.tb02733.x">10.1111/j.1365-2265.1980.tb02733.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7428183">7428183</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:27266775">27266775</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Endocrinology&rft.atitle=Plasma+prolactin+levels+after+acute+and+subchronic+oral+administration+of+domperidone+and+of+metoclopramide%3A+a+cross-over+study+in+healthy+volunteers&rft.volume=12&rft.issue=5&rft.pages=%3Cspan+class%3D%22nowrap%22%3E435-%3C%2Fspan%3E440&rft.date=1980-05&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A27266775%23id-name%3DS2CID&rft_id=info%3Apmid%2F7428183&rft_id=info%3Adoi%2F10.1111%2Fj.1365-2265.1980.tb02733.x&rft.aulast=Brouwers&rft.aufirst=JR&rft.au=Assies%2C+J&rft.au=Wiersinga%2C+WM&rft.au=Huizing%2C+G&rft.au=Tytgat%2C+GN&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid7460861-76"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid7460861_76-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFFujinoKatoYamashitaAramaki1980" class="citation journal cs1">Fujino T, Kato H, Yamashita S, Aramaki S, Morioka H, Koresawa M, et al. (August 1980). <a rel="nofollow" class="external text" href="https://doi.org/10.1507%2Fendocrj1954.27.521">"Effects of domperidone on serum prolactin levels in human beings"</a>. <i>Endocrinologia Japonica</i>. <b>27</b> (4): <span class="nowrap">521–</span>525. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1507%2Fendocrj1954.27.521">10.1507/endocrj1954.27.521</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7460861">7460861</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinologia+Japonica&rft.atitle=Effects+of+domperidone+on+serum+prolactin+levels+in+human+beings&rft.volume=27&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E521-%3C%2Fspan%3E525&rft.date=1980-08&rft_id=info%3Adoi%2F10.1507%2Fendocrj1954.27.521&rft_id=info%3Apmid%2F7460861&rft.aulast=Fujino&rft.aufirst=T&rft.au=Kato%2C+H&rft.au=Yamashita%2C+S&rft.au=Aramaki%2C+S&rft.au=Morioka%2C+H&rft.au=Koresawa%2C+M&rft.au=Miyauchi%2C+F&rft.au=Toyoshima%2C+H&rft.au=Torigoe%2C+T&rft_id=https%3A%2F%2Fdoi.org%2F10.1507%252Fendocrj1954.27.521&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Riordan2005-77"><span class="mw-cite-backlink"><b><a href="#cite_ref-Riordan2005_77-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRiordan2005" class="citation book cs1">Riordan J (January 2005). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=aiVesab_2bwC&pg=PA76"><i>Breastfeeding and Human Lactation</i></a>. Jones & Bartlett Learning. pp. 76–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-7637-4585-1" title="Special:BookSources/978-0-7637-4585-1"><bdi>978-0-7637-4585-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Breastfeeding+and+Human+Lactation&rft.pages=76-&rft.pub=Jones+%26+Bartlett+Learning&rft.date=2005-01&rft.isbn=978-0-7637-4585-1&rft.aulast=Riordan&rft.aufirst=J&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DaiVesab_2bwC%26pg%3DPA76&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Becker2001-78"><span class="mw-cite-backlink"><b><a href="#cite_ref-Becker2001_78-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBecker2001" class="citation book cs1">Becker KL (2001). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=FVfzRvaucq8C&pg=PA147"><i>Principles and Practice of Endocrinology and Metabolism</i></a>. Lippincott Williams & Wilkins. pp. 147–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-7817-1750-2" title="Special:BookSources/978-0-7817-1750-2"><bdi>978-0-7817-1750-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Principles+and+Practice+of+Endocrinology+and+Metabolism&rft.pages=147-&rft.pub=Lippincott+Williams+%26+Wilkins&rft.date=2001&rft.isbn=978-0-7817-1750-2&rft.aulast=Becker&rft.aufirst=KL&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DFVfzRvaucq8C%26pg%3DPA147&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-BardalWaechter2011-79"><span class="mw-cite-backlink"><b><a href="#cite_ref-BardalWaechter2011_79-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBardalWaechterMartin2011" class="citation book cs1">Bardal SK, Waechter JE, Martin DS (2011). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=nYPy70d1E50C&pg=PA184"><i>Applied Pharmacology</i></a>. Elsevier Health Sciences. pp. 184–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4377-0310-8" title="Special:BookSources/978-1-4377-0310-8"><bdi>978-1-4377-0310-8</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Applied+Pharmacology&rft.pages=184-&rft.pub=Elsevier+Health+Sciences&rft.date=2011&rft.isbn=978-1-4377-0310-8&rft.aulast=Bardal&rft.aufirst=SK&rft.au=Waechter%2C+JE&rft.au=Martin%2C+DS&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DnYPy70d1E50C%26pg%3DPA184&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-pmid26059917-80"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid26059917_80-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid26059917_80-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFYoussefParkmanNagar2015" class="citation journal cs1">Youssef AS, Parkman HP, Nagar S (November 2015). "Drug-drug interactions in pharmacologic management of gastroparesis". <i>Neurogastroenterology and Motility</i>. <b>27</b> (11): <span class="nowrap">1528–</span>1541. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fnmo.12614">10.1111/nmo.12614</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26059917">26059917</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:34728070">34728070</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Neurogastroenterology+and+Motility&rft.atitle=Drug-drug+interactions+in+pharmacologic+management+of+gastroparesis&rft.volume=27&rft.issue=11&rft.pages=%3Cspan+class%3D%22nowrap%22%3E1528-%3C%2Fspan%3E1541&rft.date=2015-11&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A34728070%23id-name%3DS2CID&rft_id=info%3Apmid%2F26059917&rft_id=info%3Adoi%2F10.1111%2Fnmo.12614&rft.aulast=Youssef&rft.aufirst=AS&rft.au=Parkman%2C+HP&rft.au=Nagar%2C+S&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-HospitalFormulary1991-81"><span class="mw-cite-backlink"><b><a href="#cite_ref-HospitalFormulary1991_81-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation book cs1"><a rel="nofollow" class="external text" href="https://books.google.com/books?id=3oVMAQAAIAAJ"><i>Hospital Formulary</i></a>. HFM Publishing Corporation. 1991. p. 171. <q>Domperidone, a benzimidazole derivative, is structurally related to the butyrophenone tranquilizers (eg, haloperidol (Haldol, Halperon]).</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Hospital+Formulary&rft.pages=171&rft.pub=HFM+Publishing+Corporation&rft.date=1991&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D3oVMAQAAIAAJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-BiggioCosta2013-82"><span class="mw-cite-backlink"><b><a href="#cite_ref-BiggioCosta2013_82-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFBiggioCostaSpano2013" class="citation book cs1">Biggio G, Costa E, Spano PF (22 October 2013). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=8VAJAwAAQBAJ&pg=PA3"><i>Receptors as Supramolecular Entities: Proceedings of the Biannual Capo Boi Conference, Cagliari, Italy, 7-10 June 1981</i></a>. Elsevier Science. pp. 3–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4831-5550-0" title="Special:BookSources/978-1-4831-5550-0"><bdi>978-1-4831-5550-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Receptors+as+Supramolecular+Entities%3A+Proceedings+of+the+Biannual+Capo+Boi+Conference%2C+Cagliari%2C+Italy%2C+7-10+June+1981&rft.pages=3-&rft.pub=Elsevier+Science&rft.date=2013-10-22&rft.isbn=978-1-4831-5550-0&rft.aulast=Biggio&rft.aufirst=G&rft.au=Costa%2C+E&rft.au=Spano%2C+PF&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D8VAJAwAAQBAJ%26pg%3DPA3&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-83"><span class="mw-cite-backlink"><b><a href="#cite_ref-83">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCorsini2010" class="citation book cs1">Corsini GU (2010). <a rel="nofollow" class="external text" href="https://www.webcitation.org/6TlHgQUT7?url=http://cinp.org/fileadmin/documents/history/books/VOL2_opt.pdf">"Apomorphine: from experimental tool to therapeutic aid"</a> <span class="cs1-format">(PDF)</span>. In Ban TA, Healy D, Shorter E (eds.). <i>The Triumph of Psychopharacology and the Story of CINP</i>. CINP. p. 54. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-9634081814" title="Special:BookSources/978-9634081814"><bdi>978-9634081814</bdi></a>. Archived from <a rel="nofollow" class="external text" href="http://cinp.org/fileadmin/documents/history/books/VOL2_opt.pdf">the original</a> <span class="cs1-format">(PDF)</span> on 1 November 2014.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Apomorphine%3A+from+experimental+tool+to+therapeutic+aid&rft.btitle=The+Triumph+of+Psychopharacology+and+the+Story+of+CINP&rft.pages=54&rft.pub=CINP&rft.date=2010&rft.isbn=978-9634081814&rft.aulast=Corsini&rft.aufirst=GU&rft_id=http%3A%2F%2Fcinp.org%2Ffileadmin%2Fdocuments%2Fhistory%2Fbooks%2FVOL2_opt.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-84"><span class="mw-cite-backlink"><b><a href="#cite_ref-84">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFRathboneHadgraftRoberts2002" class="citation book cs1">Rathbone MJ, Hadgraft J, Roberts MS (2002). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=mw9W82MLYZ8C&pg=PA200">"The Zydis Oral Fast-Dissolving Dosage Form"</a>. <span class="id-lock-registration" title="Free registration required"><a rel="nofollow" class="external text" href="https://archive.org/details/modifiedreleased00mich"><i>Modified-Release Drug Delivery Technology</i></a></span>. CRC Press. p. <a rel="nofollow" class="external text" href="https://archive.org/details/modifiedreleased00mich/page/200">200</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780824708696" title="Special:BookSources/9780824708696"><bdi>9780824708696</bdi></a><span class="reference-accessdate">. Retrieved <span class="nowrap">31 October</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=The+Zydis+Oral+Fast-Dissolving+Dosage+Form&rft.btitle=Modified-Release+Drug+Delivery+Technology&rft.pages=200&rft.pub=CRC+Press&rft.date=2002&rft.isbn=9780824708696&rft.aulast=Rathbone&rft.aufirst=MJ&rft.au=Hadgraft%2C+J&rft.au=Roberts%2C+MS&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Dmw9W82MLYZ8C%26pg%3DPA200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Elks2014-85"><span class="mw-cite-backlink"><b><a href="#cite_ref-Elks2014_85-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFElks2014" class="citation book cs1">Elks J (14 November 2014). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA466"><i>The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies</i></a>. Springer. pp. 466–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4757-2085-3" title="Special:BookSources/978-1-4757-2085-3"><bdi>978-1-4757-2085-3</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Dictionary+of+Drugs%3A+Chemical+Data%3A+Chemical+Data%2C+Structures+and+Bibliographies&rft.pages=466-&rft.pub=Springer&rft.date=2014-11-14&rft.isbn=978-1-4757-2085-3&rft.aulast=Elks&rft.aufirst=J&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D0vXTBwAAQBAJ%26pg%3DPA466&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-IndexNominum2000-86"><span class="mw-cite-backlink"><b><a href="#cite_ref-IndexNominum2000_86-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation book cs1"><a rel="nofollow" class="external text" href="https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA366"><i>Index Nominum 2000: International Drug Directory</i></a>. Taylor & Francis. January 2000. pp. 366–. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-3-88763-075-1" title="Special:BookSources/978-3-88763-075-1"><bdi>978-3-88763-075-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Index+Nominum+2000%3A+International+Drug+Directory&rft.pages=366-&rft.pub=Taylor+%26+Francis&rft.date=2000-01&rft.isbn=978-3-88763-075-1&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D5GpcTQD_L2oC%26pg%3DPA366&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-Drugs.com-87"><span class="mw-cite-backlink"><b><a href="#cite_ref-Drugs.com_87-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.drugs.com/international/domperidone.html">"Domperidone"</a>. <i>Drugs.com</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Drugs.com&rft.atitle=Domperidone&rft_id=https%3A%2F%2Fwww.drugs.com%2Finternational%2Fdomperidone.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-88"><span class="mw-cite-backlink"><b><a href="#cite_ref-88">^</a></b></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://www.hc-sc.gc.ca/dhp-mps/alt_formats/pdf/medeff/bulletin/carn-bcei_v17n1-eng.pdf">"Domperidone - heart rate and rhythm disorders."</a> Canadian adverse reactions newsletter. Government of Canada. January 2007 17(1)</span> </li> <li id="cite_note-89"><span class="mw-cite-backlink"><b><a href="#cite_ref-89">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.standaard.be/cnt/dmf20130507_00571810">"Motilium nog enkel op voorschrift"</a>. <i>De Standaard</i>. standaard.be. 7 May 2013<span class="reference-accessdate">. Retrieved <span class="nowrap">3 October</span> 2013</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=De+Standaard&rft.atitle=Motilium+nog+enkel+op+voorschrift&rft.date=2013-05-07&rft_id=https%3A%2F%2Fwww.standaard.be%2Fcnt%2Fdmf20130507_00571810&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-90"><span class="mw-cite-backlink"><b><a href="#cite_ref-90">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.ipcalabs.com/">"ipcalabs.com"</a>. ipcalabs.com<span class="reference-accessdate">. Retrieved <span class="nowrap">30 June</span> 2013</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=ipcalabs.com&rft.pub=ipcalabs.com&rft_id=http%3A%2F%2Fwww.ipcalabs.com%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-91"><span class="mw-cite-backlink"><b><a href="#cite_ref-91">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.torrentpharma.com/">"torrentpharma.com"</a>. torrentpharma.com<span class="reference-accessdate">. Retrieved <span class="nowrap">30 June</span> 2013</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=torrentpharma.com&rft.pub=torrentpharma.com&rft_id=http%3A%2F%2Fwww.torrentpharma.com%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> <li id="cite_note-HofmeyrVan_Iddekinge2009-92"><span class="mw-cite-backlink"><b><a href="#cite_ref-HofmeyrVan_Iddekinge2009_92-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFHofmeyrVan_IddekingeVan_Der_Walt1985" class="citation journal cs1">Hofmeyr GJ, Van Iddekinge B, Van Der Walt LA (1985). "Effect of domperidone-induced hyperprolactinaemia on the menstrual cycle; a placebo-controlled study". <i>Journal of Obstetrics and Gynaecology</i>. <b>5</b> (4): <span class="nowrap">263–</span>264. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3109%2F01443618509067772">10.3109/01443618509067772</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0144-3615">0144-3615</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Obstetrics+and+Gynaecology&rft.atitle=Effect+of+domperidone-induced+hyperprolactinaemia+on+the+menstrual+cycle%3B+a+placebo-controlled+study&rft.volume=5&rft.issue=4&rft.pages=%3Cspan+class%3D%22nowrap%22%3E263-%3C%2Fspan%3E264&rft.date=1985&rft_id=info%3Adoi%2F10.3109%2F01443618509067772&rft.issn=0144-3615&rft.aulast=Hofmeyr&rft.aufirst=GJ&rft.au=Van+Iddekinge%2C+B&rft.au=Van+Der+Walt%2C+LA&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADomperidone" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output .navbox,.mw-parser-output .navbox-subgroup{background-color:#fdfdfd}.mw-parser-output .navbox-list{line-height:1.5em;border-color:#fdfdfd}.mw-parser-output .navbox-list-with-group{text-align:left;border-left-width:2px;border-left-style:solid}.mw-parser-output tr+tr>.navbox-abovebelow,.mw-parser-output tr+tr>.navbox-group,.mw-parser-output tr+tr>.navbox-image,.mw-parser-output tr+tr>.navbox-list{border-top:2px solid #fdfdfd}.mw-parser-output .navbox-title{background-color:#ccf}.mw-parser-output .navbox-abovebelow,.mw-parser-output .navbox-group,.mw-parser-output .navbox-subgroup .navbox-title{background-color:#ddf}.mw-parser-output .navbox-subgroup .navbox-group,.mw-parser-output .navbox-subgroup .navbox-abovebelow{background-color:#e6e6ff}.mw-parser-output .navbox-even{background-color:#f7f7f7}.mw-parser-output .navbox-odd{background-color:transparent}.mw-parser-output .navbox .hlist td dl,.mw-parser-output .navbox .hlist td ol,.mw-parser-output .navbox .hlist td ul,.mw-parser-output .navbox td.hlist dl,.mw-parser-output .navbox td.hlist ol,.mw-parser-output .navbox td.hlist ul{padding:0.125em 0}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}body.skin--responsive .mw-parser-output .navbox-image img{max-width:none!important}@media print{body.ns-0 .mw-parser-output .navbox{display:none!important}}</style></div><div role="navigation" class="navbox" aria-labelledby="Medical_uses101" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e8e8ff;background:#ccccff"><div id="Medical_uses101" style="font-size:114%;margin:0 4em"><a href="/wiki/Medical_use" class="mw-redirect" title="Medical use">Medical uses</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;font-size:114%"><div style="padding:0px"> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Drugs_for_functional_gastrointestinal_disorders_(A03)293" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Drugs_for_functional_gastrointestinal_disorders" title="Template:Drugs for functional gastrointestinal disorders"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Drugs_for_functional_gastrointestinal_disorders" title="Template talk:Drugs for functional gastrointestinal disorders"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Drugs_for_functional_gastrointestinal_disorders" title="Special:EditPage/Template:Drugs for functional gastrointestinal disorders"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Drugs_for_functional_gastrointestinal_disorders_(A03)293" style="font-size:114%;margin:0 4em">Drugs for <a href="/wiki/Functional_gastrointestinal_disorder" title="Functional gastrointestinal disorder">functional gastrointestinal disorders</a> (<a href="/wiki/ATC_code_A03" title="ATC code A03">A03</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Drugs for<br /> <a href="/wiki/Functional_gastrointestinal_disorder" title="Functional gastrointestinal disorder">functional<br /> bowel <br />disorders</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Muscarinic_antagonist" title="Muscarinic antagonist">Antimuscarinics</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Tertiary<br /> amino group</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Camylofin" title="Camylofin">Camylofin</a></li> <li><a href="/wiki/Dicycloverine" title="Dicycloverine">Dicycloverine</a></li> <li><a href="/wiki/Difemerine" title="Difemerine">Difemerine</a></li> <li><a href="/wiki/Dihexyverine" title="Dihexyverine">Dihexyverine</a></li> <li><a href="/wiki/Mebeverine" title="Mebeverine">Mebeverine</a></li> <li><a href="/wiki/Oxyphencyclimine" title="Oxyphencyclimine">Oxyphencyclimine</a></li> <li><a href="/wiki/Piperidolate" title="Piperidolate">Piperidolate</a></li> <li><a href="/wiki/Rociverine" title="Rociverine">Rociverine</a></li> <li><a href="/wiki/Trimebutine" title="Trimebutine">Trimebutine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Quaternary_ammonium" class="mw-redirect" title="Quaternary ammonium">Quaternary<br /> ammonium</a><br /> compounds</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Benzilone" title="Benzilone">Benzilone</a></li> <li><a href="/wiki/Bevonium" title="Bevonium">Bevonium</a></li> <li><a href="/wiki/Diphemanil_metilsulfate" title="Diphemanil metilsulfate">Diphemanil</a></li> <li><a href="/wiki/Fenpiverinium" title="Fenpiverinium">Fenpiverinium</a></li> <li><a href="/wiki/Glycopyrronium_bromide" title="Glycopyrronium bromide">Glycopyrronium</a></li> <li><a href="/wiki/Hexocyclium" title="Hexocyclium">Hexocyclium</a></li> <li><a href="/wiki/Isopropamide" title="Isopropamide">Isopropamide</a></li> <li><a href="/wiki/Mepenzolate" title="Mepenzolate">Mepenzolate</a></li> <li><a href="/wiki/Methantheline" title="Methantheline">Methantheline</a></li> <li><a href="/wiki/Otilonium_bromide" title="Otilonium bromide">Otilonium</a></li> <li><a href="/wiki/Oxyphenonium_bromide" title="Oxyphenonium bromide">Oxyphenonium</a></li> <li><a href="/wiki/Penthienate" title="Penthienate">Penthienate</a></li> <li><a href="/wiki/Pipenzolate" class="mw-redirect" title="Pipenzolate">Pipenzolate</a></li> <li><a href="/wiki/Poldine" title="Poldine">Poldine</a></li> <li><a href="/wiki/Prifinium_bromide" title="Prifinium bromide">Prifinium</a></li> <li><a href="/wiki/Propantheline" class="mw-redirect" title="Propantheline">Propantheline</a></li> <li><a href="/wiki/Tiemonium_iodide" title="Tiemonium iodide">Tiemonium</a></li> <li><a href="/wiki/Timepidium_bromide" title="Timepidium bromide">Timepidium</a></li> <li><a href="/wiki/Tridihexethyl" title="Tridihexethyl">Tridihexethyl</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Phosphodiesterase_inhibitor" title="Phosphodiesterase inhibitor">Phosphodiesterase<br /> inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Drotaverine" title="Drotaverine">Drotaverine</a></li> <li><a href="/wiki/Moxaverine" title="Moxaverine">Moxaverine</a></li> <li><a href="/wiki/Papaverine" title="Papaverine">Papaverine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Acting on<br /> <a href="/wiki/5-HT_receptor" title="5-HT receptor">serotonin receptors</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/5-HT3_antagonist" title="5-HT3 antagonist">5-HT<sub>3</sub> antagonists</a></i> <ul><li><a href="/wiki/Alosetron" title="Alosetron">Alosetron</a></li> <li><a href="/wiki/Cilansetron" title="Cilansetron">Cilansetron</a></li></ul></li> <li><i><a href="/wiki/Serotonin_receptor_agonist" title="Serotonin receptor agonist">5-HT<sub>4</sub> agonists</a></i> <ul><li><a href="/wiki/Mosapride" title="Mosapride">Mosapride</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Alverine" title="Alverine">Alverine</a></li> <li><a href="/wiki/Caroverine" title="Caroverine">Caroverine</a></li> <li><a href="/wiki/Chlorbenzoxamine" title="Chlorbenzoxamine">Chlorbenzoxamine</a></li> <li><a href="/wiki/Diisopromine" title="Diisopromine">Diisopromine</a></li> <li><a href="/wiki/Dimethylaminopropionylphenothiazine" title="Dimethylaminopropionylphenothiazine">Dimethylaminopropionylphenothiazine</a></li> <li><a href="/wiki/Fenoverine" title="Fenoverine">Fenoverine</a></li> <li><a href="/wiki/Fenpiprane" title="Fenpiprane">Fenpiprane</a></li> <li><a href="/wiki/Idanpramine" title="Idanpramine">Idanpramine</a></li> <li><a href="/wiki/Isometheptene" title="Isometheptene">Isometheptene</a></li> <li><a href="/wiki/Mentha_piperita" class="mw-redirect" title="Mentha piperita">Mentha piperita</a></li> <li><a href="/wiki/Phloroglucinol" title="Phloroglucinol">Phloroglucinol</a></li> <li><a href="/wiki/Pinaverium_bromide" title="Pinaverium bromide">Pinaverium bromide</a></li> <li><a href="/wiki/Proxazole" title="Proxazole">Proxazole</a></li> <li><a href="/wiki/Simeticone" title="Simeticone">Simeticone</a></li> <li><a href="/wiki/Tiropramide" title="Tiropramide">Tiropramide</a></li> <li><a href="/wiki/Trepibutone" title="Trepibutone">Trepibutone</a></li> <li><a href="/wiki/Trimethyldiphenylpropylamine" title="Trimethyldiphenylpropylamine">Trimethyldiphenylpropylamine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Atropa_belladonna" class="mw-redirect" title="Atropa belladonna">Belladonna</a><br /> and derivatives<br /> (<a href="/wiki/Muscarinic_antagonist" title="Muscarinic antagonist">antimuscarinics</a>)</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Tertiary amines:</i> <a href="/wiki/Atropine" title="Atropine">Atropine</a></li> <li><a href="/wiki/Hyoscyamine" title="Hyoscyamine">Hyoscyamine</a></li></ul> <ul><li><i>Quaternary ammonium compounds:</i> <ul><li><a href="/wiki/Hyoscine_hydrobromide" class="mw-redirect" title="Hyoscine hydrobromide">Scopolamine</a></li> <li><a href="/wiki/Butylscopolamine" class="mw-redirect" title="Butylscopolamine">Butylscopolamine</a></li> <li><a href="/wiki/Methylscopolamine_bromide" title="Methylscopolamine bromide">Methylscopolamine</a></li></ul></li> <li><a href="/wiki/Cimetropium_bromide" title="Cimetropium bromide">Cimetropium bromide</a></li> <li><a href="/wiki/Fentonium_bromide" title="Fentonium bromide">Fentonium bromide</a></li> <li><a href="/wiki/Methylatropine" title="Methylatropine">Methylatropine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Prokinetic" class="mw-redirect" title="Prokinetic">Propulsives</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Dopamine_antagonist" title="Dopamine antagonist">Primarily dopamine antagonists</a></i> <ul><li><a href="/wiki/Alizapride" title="Alizapride">Alizapride</a></li> <li><a href="/wiki/Bromopride" title="Bromopride">Bromopride</a></li> <li><a href="/wiki/Clebopride" title="Clebopride">Clebopride</a></li> <li><a class="mw-selflink selflink">Domperidone</a></li> <li><a href="/wiki/Metoclopramide" title="Metoclopramide">Metoclopramide</a></li></ul></li> <li><i><a href="/wiki/Serotonin_receptor_agonist" title="Serotonin receptor agonist">5-HT<sub>4</sub> agonists</a></i> <ul><li><a href="/wiki/Cinitapride" title="Cinitapride">Cinitapride</a></li> <li><a href="/wiki/Cisapride" title="Cisapride">Cisapride</a></li></ul></li> <li><a href="/wiki/Acotiamide" title="Acotiamide">Acotiamide</a></li> <li><a href="/w/index.php?title=Ilebopride&action=edit&redlink=1" class="new" title="Ilebopride (page does not exist)">Ilebopride</a></li> <li><a href="/wiki/Mosapride" title="Mosapride">Mosapride</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Galactagogues77" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Galactagogues" title="Template:Galactagogues"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Galactagogues" title="Template talk:Galactagogues"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Galactagogues" title="Special:EditPage/Template:Galactagogues"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Galactagogues77" style="font-size:114%;margin:0 4em"><a href="/wiki/Galactagogue" title="Galactagogue">Galactagogues</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Prolactin_receptor_agonist" class="mw-redirect" title="Prolactin receptor agonist">Prolactin receptor agonists</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Growth_hormone" title="Growth hormone">Growth hormone</a>/<a href="/wiki/Somatotropin" class="mw-redirect" title="Somatotropin">somatotropin</a></li> <li><a href="/wiki/Human_placental_lactogen" title="Human placental lactogen">Human placental lactogen</a></li> <li><a href="/wiki/Prolactin" title="Prolactin">Prolactin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Prolactin_releaser" class="mw-redirect" title="Prolactin releaser">Prolactin releasers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Dopamine_antagonist" title="Dopamine antagonist">D<sub>2</sub> receptor antagonists</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Antiemetics/gastroprokinetic agents:</i> <a class="mw-selflink selflink">Domperidone</a></li> <li><a href="/wiki/Metoclopramide" title="Metoclopramide">Metoclopramide</a></li></ul> <ul><li><i>Antipsychotics:</i> <a href="/wiki/Chlorpromazine" title="Chlorpromazine">Chlorpromazine</a></li> <li><a href="/wiki/Risperidone" title="Risperidone">Risperidone</a></li> <li><a href="/wiki/Sulpiride" title="Sulpiride">Sulpiride</a></li> <li>Others</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Estrogen_(medication)" title="Estrogen (medication)">Estrogens</a></li> <li><a href="/wiki/Progestogen_(medication)" title="Progestogen (medication)">Progestogens</a></li> <li><a href="/wiki/Thyrotropin-releasing_hormone" title="Thyrotropin-releasing hormone">Thyrotropin-releasing hormone</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Breast development inducers:</i> <a href="/wiki/Estrogen_(medication)" title="Estrogen (medication)">Estrogens</a> (e.g., <a href="/wiki/Estradiol_(medication)" title="Estradiol (medication)">estradiol</a>)</li> <li><a href="/wiki/Progestogen_(medication)" title="Progestogen (medication)">Progestogens</a> (e.g., <a href="/wiki/Progesterone_(medication)" title="Progesterone (medication)">progesterone</a>, <a href="/wiki/Medroxyprogesterone_acetate" title="Medroxyprogesterone acetate">medroxyprogesterone acetate</a>, <a href="/wiki/Cyproterone_acetate" title="Cyproterone acetate">cyproterone acetate</a>)</li></ul> <ul><li><i>Milk letdown inducers:</i> <a href="/wiki/Oxytocin" title="Oxytocin">Oxytocin</a></li></ul> </div></td></tr></tbody></table></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Pharmacodynamics105" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e8e8ff;background:#ccccff"><div id="Pharmacodynamics105" style="font-size:114%;margin:0 4em"><a href="/wiki/Pharmacodynamics" title="Pharmacodynamics">Pharmacodynamics</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;font-size:114%"><div style="padding:0px"> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Dopamine_receptor_modulators745" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Dopamine_receptor_modulators" title="Template:Dopamine receptor modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Dopamine_receptor_modulators" title="Template talk:Dopamine receptor modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Dopamine_receptor_modulators" title="Special:EditPage/Template:Dopamine receptor modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Dopamine_receptor_modulators745" style="font-size:114%;margin:0 4em"><a href="/wiki/Dopamine_receptor" title="Dopamine receptor">Dopamine receptor</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/D1-like_receptor" title="D1-like receptor">D<sub>1</sub>-like</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Agonists</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Benzazepines</i>: <a href="/wiki/6-Br-APB" title="6-Br-APB">6-Br-APB</a></li> <li><a href="/wiki/Fenoldopam" title="Fenoldopam">Fenoldopam</a></li> <li><a href="/wiki/SKF-38,393" title="SKF-38,393">SKF-38,393</a></li> <li><a href="/wiki/SKF-77,434" title="SKF-77,434">SKF-77,434</a></li> <li><a href="/wiki/SKF-81,297" title="SKF-81,297">SKF-81,297</a></li> <li><a href="/wiki/SKF-82,958" title="SKF-82,958">SKF-82,958</a></li> <li><a href="/wiki/SKF-83,959" title="SKF-83,959">SKF-83,959</a></li> <li><a href="/wiki/Trepipam" title="Trepipam">Trepipam</a></li> <li><a href="/wiki/Zelandopam" title="Zelandopam">Zelandopam</a></li></ul> <ul><li><i>Ergolines</i>: <a href="/wiki/Cabergoline" title="Cabergoline">Cabergoline</a></li> <li><a href="/wiki/CY-208,243" title="CY-208,243">CY-208,243</a></li> <li><a href="/wiki/Dihydroergocryptine" title="Dihydroergocryptine">Dihydroergocryptine</a></li> <li><a href="/w/index.php?title=LEK-8829&action=edit&redlink=1" class="new" title="LEK-8829 (page does not exist)">LEK-8829</a></li> <li><a href="/wiki/Lisuride" title="Lisuride">Lisuride</a></li> <li><a href="/wiki/Pergolide" title="Pergolide">Pergolide</a></li> <li><a href="/wiki/Terguride" title="Terguride">Terguride</a></li></ul> <ul><li><i>Dihydrexidine derivatives</i>: <a href="/wiki/A-77636" title="A-77636">A-77636</a></li> <li><a href="/wiki/A-86929" title="A-86929">A-86929</a></li> <li><a href="/wiki/Adrogolide" class="mw-redirect" title="Adrogolide">Adrogolide (ABT-431, DAS-431)</a></li> <li><a href="/wiki/Dihydrexidine" title="Dihydrexidine">Dihydrexidine</a></li> <li><a href="/wiki/Dinapsoline" title="Dinapsoline">Dinapsoline</a></li> <li><a href="/wiki/Dinoxyline" title="Dinoxyline">Dinoxyline</a></li> <li><a href="/wiki/Doxanthrine" title="Doxanthrine">Doxanthrine</a></li></ul> <ul><li><i>Phenethylamines</i>: <a href="/w/index.php?title=BCO-001&action=edit&redlink=1" class="new" title="BCO-001 (page does not exist)">BCO-001</a></li> <li><a href="/wiki/Deoxyepinephrine" title="Deoxyepinephrine">Deoxyepinephrine (N-methyldopamine, epinine)</a></li> <li><a href="/wiki/Dopexamine" title="Dopexamine">Dopexamine</a></li> <li><a href="/wiki/Etilevodopa" title="Etilevodopa">Etilevodopa</a></li> <li><a href="/wiki/Ibopamine" title="Ibopamine">Ibopamine</a></li> <li><a href="/wiki/L-DOPA" title="L-DOPA"><small>L</small>-DOPA (levodopa)</a></li> <li><a href="/wiki/Melevodopa" title="Melevodopa">Melevodopa</a></li> <li><a href="/wiki/Phenylalanine" title="Phenylalanine"><small>L</small>-Phenylalanine</a></li> <li><a href="/wiki/Tyrosine" title="Tyrosine"><small>L</small>-Tyrosine</a></li> <li><a href="/wiki/XP21279" class="mw-redirect" title="XP21279">XP21279</a></li></ul> <ul><li><i>Others</i>: <a href="/wiki/A-68930" title="A-68930">A-68930</a></li> <li><a href="/wiki/Apomorphine" title="Apomorphine">Apomorphine</a></li> <li><a href="/w/index.php?title=Isocorypalmine&action=edit&redlink=1" class="new" title="Isocorypalmine (page does not exist)">Isocorypalmine</a></li> <li><a href="/wiki/Nuciferine" title="Nuciferine">Nuciferine</a></li> <li><a href="/wiki/PF-6649751" class="mw-redirect" title="PF-6649751">PF-6649751</a></li> <li><a href="/w/index.php?title=PF_6669571&action=edit&redlink=1" class="new" title="PF 6669571 (page does not exist)">PF 6669571</a></li> <li><a href="/wiki/Propylnorapomorphine" title="Propylnorapomorphine">Propylnorapomorphine</a></li> <li><a href="/wiki/Rotigotine" title="Rotigotine">Rotigotine</a></li> <li><a href="/wiki/SKF-89,145" title="SKF-89,145">SKF-89,145</a></li> <li><a href="/w/index.php?title=SKF-89,626&action=edit&redlink=1" class="new" title="SKF-89,626 (page does not exist)">SKF-89,626</a></li> <li><a href="/wiki/Stepholidine" title="Stepholidine">Stepholidine</a></li> <li><a href="/wiki/Tavapadon" title="Tavapadon">Tavapadon</a></li> <li><a href="/wiki/Tetrahydropalmatine" title="Tetrahydropalmatine">Tetrahydropalmatine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><abbr title="Positive allosteric modulators">PAMs</abbr></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Tetrahydroisoquinolines</i>: <a href="/w/index.php?title=DETQ&action=edit&redlink=1" class="new" title="DETQ (page does not exist)">DETQ</a></li> <li><a href="/w/index.php?title=DPTQ&action=edit&redlink=1" class="new" title="DPTQ (page does not exist)">DPTQ</a></li> <li><a href="/wiki/Mevidalen" title="Mevidalen">Mevidalen</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Antagonists</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Typical antipsychotics</i>: <a href="/wiki/Butaclamol" title="Butaclamol">Butaclamol</a></li> <li><a href="/wiki/Chlorpromazine" title="Chlorpromazine">Chlorpromazine</a></li> <li><a href="/wiki/Chlorprothixene" title="Chlorprothixene">Chlorprothixene</a></li> <li><a href="/wiki/Flupentixol" title="Flupentixol">Flupentixol (flupenthixol)</a> (<a href="/wiki/Flupentixol/melitracen" title="Flupentixol/melitracen">+melitracen</a>)</li> <li><a href="/wiki/Fluphenazine" title="Fluphenazine">Fluphenazine</a></li> <li><a href="/wiki/Loxapine" title="Loxapine">Loxapine</a></li> <li><a href="/wiki/Perphenazine" title="Perphenazine">Perphenazine</a> (<a href="/wiki/Amitriptyline/perphenazine" title="Amitriptyline/perphenazine">+amitriptyline</a>)</li> <li><a href="/w/index.php?title=Pifluthixol&action=edit&redlink=1" class="new" title="Pifluthixol (page does not exist)">Pifluthixol</a></li> <li><a href="/wiki/Thioridazine" title="Thioridazine">Thioridazine</a></li> <li><a href="/wiki/Thiothixene" class="mw-redirect" title="Thiothixene">Thiothixene</a></li> <li><a href="/wiki/Trifluoperazine" title="Trifluoperazine">Trifluoperazine</a> (<a href="/wiki/Tranylcypromine/trifluoperazine" title="Tranylcypromine/trifluoperazine">+tranylcypromine</a>)</li> <li><a href="/wiki/Zuclopenthixol" title="Zuclopenthixol">Zuclopenthixol</a></li></ul> <ul><li><i>Atypical antipsychotics</i>: <a href="/wiki/Asenapine" title="Asenapine">Asenapine</a></li> <li><a href="/wiki/Clorotepine" title="Clorotepine">Clorotepine</a></li> <li><a href="/wiki/Clotiapine" title="Clotiapine">Clotiapine</a></li> <li><a href="/wiki/Clozapine" title="Clozapine">Clozapine</a></li> <li><a href="/wiki/DHA-clozapine" title="DHA-clozapine">DHA-clozapine</a></li> <li><a href="/wiki/Fluperlapine" title="Fluperlapine">Fluperlapine</a></li> <li><a href="/wiki/Iloperidone" title="Iloperidone">Iloperidone</a></li> <li><a href="/wiki/Norclozapine" class="mw-redirect" title="Norclozapine">Norclozapine</a></li> <li><a href="/w/index.php?title=Norquetiapine&action=edit&redlink=1" class="new" title="Norquetiapine (page does not exist)">Norquetiapine</a></li> <li><a href="/wiki/Olanzapine" title="Olanzapine">Olanzapine</a> (<a href="/wiki/Olanzapine/fluoxetine" title="Olanzapine/fluoxetine">+fluoxetine</a>)</li> <li><a href="/wiki/Paliperidone" title="Paliperidone">Paliperidone</a></li> <li><a href="/wiki/Quetiapine" title="Quetiapine">Quetiapine</a></li> <li><a href="/wiki/Risperidone" title="Risperidone">Risperidone</a></li> <li><a href="/w/index.php?title=Tefludazine&action=edit&redlink=1" class="new" title="Tefludazine (page does not exist)">Tefludazine</a></li> <li><a href="/wiki/Zicronapine" title="Zicronapine">Zicronapine</a></li> <li><a href="/wiki/Ziprasidone" title="Ziprasidone">Ziprasidone</a></li> <li><a href="/wiki/Zotepine" title="Zotepine">Zotepine</a></li></ul> <ul><li><i>Others</i>: <a href="/wiki/Berupipam" title="Berupipam">Berupipam</a></li> <li><a href="/wiki/Ecopipam" title="Ecopipam">Ecopipam</a></li> <li><a href="/wiki/N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline" title="N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline">EEDQ</a></li> <li><a href="/wiki/Metitepine" title="Metitepine">Metitepine (methiothepin)</a></li> <li><a href="/wiki/Odapipam" title="Odapipam">Odapipam</a></li> <li><a href="/wiki/Perlapine" title="Perlapine">Perlapine</a></li> <li><a href="/wiki/SCH-23390" title="SCH-23390">SCH-23390</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/D2-like_receptor" title="D2-like receptor">D<sub>2</sub>-like</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Agonists</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Adamantanes</i>: <a href="/wiki/Amantadine" title="Amantadine">Amantadine</a></li> <li><a href="/wiki/Memantine" title="Memantine">Memantine</a></li> <li><a href="/wiki/Rimantadine" title="Rimantadine">Rimantadine</a></li></ul> <ul><li><i>Aminotetralins</i>: <a href="/wiki/5-OH-DPAT" title="5-OH-DPAT">5-OH-DPAT</a></li> <li><a href="/wiki/7-OH-DPAT" title="7-OH-DPAT">7-OH-DPAT</a></li> <li><a href="/wiki/8-OH-PBZI" title="8-OH-PBZI">8-OH-PBZI</a></li> <li><a href="/wiki/Rotigotine" title="Rotigotine">Rotigotine</a></li> <li><a href="/wiki/UH-232" title="UH-232">UH-232</a></li></ul> <ul><li><i>Ergolines</i>: <a href="/wiki/Bromocriptine" title="Bromocriptine">Bromocriptine</a></li> <li><a href="/wiki/Cabergoline" title="Cabergoline">Cabergoline</a></li> <li><a href="/wiki/Chanoclavine" title="Chanoclavine">Chanoclavine</a></li> <li><a href="/wiki/Dihydroergocryptine" title="Dihydroergocryptine">Dihydroergocryptine</a></li> <li><a href="/wiki/Epicriptine" title="Epicriptine">Epicriptine</a></li> <li><a href="/wiki/Ergocornine" title="Ergocornine">Ergocornine</a></li> <li><a href="/wiki/Lergotrile" title="Lergotrile">Lergotrile</a></li> <li><a href="/wiki/Lisuride" title="Lisuride">Lisuride</a></li> <li><a href="/wiki/LSD" title="LSD">LSD</a></li> <li><a href="/wiki/Pergolide" title="Pergolide">Pergolide</a></li> <li><a href="/wiki/Terguride" title="Terguride">Terguride</a></li></ul> <ul><li><i>Dihydrexidine derivatives</i>: <a href="/wiki/2-OH-NPA" title="2-OH-NPA">2-OH-NPA</a></li> <li><a href="/wiki/Ciladopa" title="Ciladopa">Ciladopa</a></li> <li><a href="/wiki/Dihydrexidine" title="Dihydrexidine">Dihydrexidine</a></li> <li><a href="/wiki/Dinoxyline" title="Dinoxyline">Dinoxyline</a></li> <li><a href="/w/index.php?title=N,N-Propyldihydrexidine&action=edit&redlink=1" class="new" title="N,N-Propyldihydrexidine (page does not exist)">N,N-Propyldihydrexidine</a></li></ul> <ul><li><i>Phenethylamines</i>: <a href="/wiki/Deoxyepinephrine" title="Deoxyepinephrine">Deoxyepinephrine (N-methyldopamine, epinine)</a></li> <li><a href="/wiki/Dopexamine" title="Dopexamine">Dopexamine</a></li> <li><a href="/wiki/Etilevodopa" title="Etilevodopa">Etilevodopa</a></li> <li><a href="/wiki/Ibopamine" title="Ibopamine">Ibopamine</a></li> <li><a href="/wiki/L-DOPA" title="L-DOPA"><small>L</small>-DOPA (levodopa)</a></li> <li><a href="/wiki/Phenylalanine" title="Phenylalanine"><small>L</small>-Phenylalanine</a></li> <li><a href="/wiki/Tyrosine" title="Tyrosine"><small>L</small>-Tyrosine</a></li> <li><a href="/wiki/Melevodopa" title="Melevodopa">Melevodopa</a></li> <li><a href="/wiki/XP21279" class="mw-redirect" title="XP21279">XP21279</a></li></ul> <ul><li><i>Atypical antipsychotics</i>: <a href="/wiki/Alentemol" title="Alentemol">Alentemol (U-66444B)</a></li> <li><a href="/wiki/Aripiprazole" title="Aripiprazole">Aripiprazole</a> (<a href="/wiki/Aripiprazole/sertraline" title="Aripiprazole/sertraline">+sertraline</a>)</li> <li><a href="/wiki/Aripiprazole_lauroxil" title="Aripiprazole lauroxil">Aripiprazole lauroxil</a></li> <li><a href="/wiki/Bifeprunox" title="Bifeprunox">Bifeprunox</a></li> <li><a href="/wiki/Brexpiprazole" title="Brexpiprazole">Brexpiprazole</a></li> <li><a href="/wiki/Brilaroxazine" title="Brilaroxazine">Brilaroxazine</a></li> <li><a href="/wiki/Cariprazine" title="Cariprazine">Cariprazine</a></li> <li><a href="/wiki/F-15063" title="F-15063">F-15063</a></li> <li><a href="/wiki/Lumateperone" title="Lumateperone">Lumateperone</a></li> <li><a href="/wiki/Norclozapine" class="mw-redirect" title="Norclozapine">Norclozapine</a></li></ul> <ul><li><i>Others</i>: <a href="/wiki/3-PPP" title="3-PPP">3-PPP</a></li> <li><a href="/wiki/A-412997" title="A-412997">A-412997</a></li> <li><a href="/wiki/ABT-670" title="ABT-670">ABT-670</a></li> <li><a href="/wiki/ABT-724" title="ABT-724">ABT-724</a></li> <li><a href="/wiki/Adrafinil" title="Adrafinil">Adrafinil</a></li> <li><a href="/wiki/Aplindore" title="Aplindore">Aplindore</a></li> <li><a href="/wiki/Apomorphine" title="Apomorphine">Apomorphine</a></li> <li><a href="/wiki/Arketamine" title="Arketamine">Arketamine</a></li> <li><a href="/wiki/Armodafinil" title="Armodafinil">Armodafinil</a></li> <li><a href="/wiki/BP-897" title="BP-897">BP-897</a></li> <li><a href="/wiki/Captodiame" title="Captodiame">Captodiame</a></li> <li><a href="/wiki/CP-226,269" title="CP-226,269">CP-226,269</a></li> <li><a href="/wiki/Dizocilpine" title="Dizocilpine">Dizocilpine</a></li> <li><a href="/wiki/Esketamine" title="Esketamine">Esketamine</a></li> <li><a href="/wiki/Flibanserin" title="Flibanserin">Flibanserin</a></li> <li><a href="/wiki/Ketamine" title="Ketamine">Ketamine</a></li> <li><a href="/wiki/Mesulergine" title="Mesulergine">Mesulergine</a></li> <li><a href="/wiki/Modafinil" title="Modafinil">Modafinil</a></li> <li><a href="/wiki/Naxagolide" title="Naxagolide">Naxagolide</a></li> <li><a href="/wiki/OSU-6162" title="OSU-6162">OSU-6162</a></li> <li><a href="/wiki/Pardoprunox" title="Pardoprunox">Pardoprunox</a></li> <li><a href="/wiki/PD-128,907" title="PD-128,907">PD-128,907</a></li> <li><a href="/wiki/PD-168,077" title="PD-168,077">PD-168,077</a></li> <li><a href="/wiki/PF-219,061" title="PF-219,061">PF-219,061</a></li> <li><a href="/wiki/PF-592,379" title="PF-592,379">PF-592,379</a></li> <li><a href="/wiki/Phencyclidine" title="Phencyclidine">Phencyclidine</a></li> <li><a href="/wiki/Piribedil" title="Piribedil">Piribedil</a></li> <li><a href="/wiki/Pramipexole" title="Pramipexole">Pramipexole</a></li> <li><a href="/wiki/Preclamol" class="mw-redirect" title="Preclamol">Preclamol</a></li> <li><a href="/wiki/Propylnorapomorphine" title="Propylnorapomorphine">Propylnorapomorphine</a></li> <li><a href="/wiki/Pukateine" title="Pukateine">Pukateine</a></li> <li><a href="/wiki/Quinagolide" title="Quinagolide">Quinagolide</a></li> <li><a href="/wiki/Quinelorane" title="Quinelorane">Quinelorane</a></li> <li><a href="/wiki/Quinpirole" title="Quinpirole">Quinpirole</a></li> <li><a href="/wiki/RDS-127" title="RDS-127">RDS-127</a></li> <li><a href="/wiki/Ro10-5824" title="Ro10-5824">Ro10-5824</a></li> <li><a href="/wiki/Ropinirole" title="Ropinirole">Ropinirole</a></li> <li><a href="/wiki/Roxindole" title="Roxindole">Roxindole</a></li> <li><a href="/wiki/Salvinorin_A" title="Salvinorin A">Salvinorin A</a></li> <li><a href="/wiki/SKF-83,959" title="SKF-83,959">SKF-83,959</a></li> <li><a href="/wiki/Sumanirole" title="Sumanirole">Sumanirole</a></li> <li><a href="/wiki/Talipexole" title="Talipexole">Talipexole</a></li> <li><a href="/wiki/Umespirone" title="Umespirone">Umespirone</a></li> <li><a href="/wiki/WAY-100,635" class="mw-redirect" title="WAY-100,635">WAY-100,635</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Antagonists</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>Typical antipsychotics</i>: <a href="/wiki/Acepromazine" title="Acepromazine">Acepromazine</a></li> <li><a href="/wiki/Acetophenazine" title="Acetophenazine">Acetophenazine</a></li> <li><a href="/wiki/Azaperone" title="Azaperone">Azaperone</a></li> <li><a href="/wiki/Benperidol" title="Benperidol">Benperidol</a></li> <li><a href="/wiki/Bromperidol" title="Bromperidol">Bromperidol</a></li> <li><a href="/wiki/Butaclamol" title="Butaclamol">Butaclamol</a></li> <li><a href="/wiki/Butaperazine" title="Butaperazine">Butaperazine</a></li> <li><a href="/wiki/Chloracizine" class="mw-redirect" title="Chloracizine">Chloracizine</a></li> <li><a href="/wiki/Chlorproethazine" title="Chlorproethazine">Chlorproethazine</a></li> <li><a href="/wiki/Chlorpromazine" title="Chlorpromazine">Chlorpromazine</a></li> <li><a href="/wiki/Chlorprothixene" title="Chlorprothixene">Chlorprothixene</a></li> <li><a href="/wiki/Ciclindole" title="Ciclindole">Ciclindole</a></li> <li><a href="/wiki/Clopenthixol" title="Clopenthixol">Clopenthixol</a></li> <li><a href="/w/index.php?title=Clothixamide&action=edit&redlink=1" class="new" title="Clothixamide (page does not exist)">Clothixamide</a></li> <li><a href="/wiki/Clopimozide" title="Clopimozide">Clopimozide</a></li> <li><a href="/wiki/Droperidol" title="Droperidol">Droperidol</a></li> <li><a href="/wiki/Fluacizine" title="Fluacizine">Fluacizine</a></li> <li><a href="/wiki/Fluanisone" title="Fluanisone">Fluanisone</a></li> <li><a href="/wiki/Flucindole" title="Flucindole">Flucindole</a></li> <li><a href="/wiki/Fluotracen" title="Fluotracen">Fluotracen</a></li> <li><a href="/wiki/Flupentixol" title="Flupentixol">Flupentixol (flupenthixol)</a> (<a href="/wiki/Flupentixol/melitracen" title="Flupentixol/melitracen">+melitracen</a>)</li> <li><a href="/wiki/Fluphenazine" title="Fluphenazine">Fluphenazine</a></li> <li><a href="/w/index.php?title=Fluprothixene&action=edit&redlink=1" class="new" title="Fluprothixene (page does not exist)">Fluprothixene</a></li> <li><a href="/wiki/Fluspirilene" title="Fluspirilene">Fluspirilene</a></li> <li><a href="/wiki/Haloperidol" title="Haloperidol">Haloperidol</a></li> <li><a href="/wiki/Homopipramol" title="Homopipramol">Homopipramol</a></li> <li><a href="/wiki/Lenperone" title="Lenperone">Lenperone</a></li> <li><a href="/wiki/Levomepromazine" title="Levomepromazine">Levomepromazine (methotrimeprazine)</a></li> <li><a href="/wiki/Levosulpiride" title="Levosulpiride">Levosulpiride</a></li> <li><a href="/wiki/Loxapine" title="Loxapine">Loxapine</a></li> <li><a href="/wiki/Mesoridazine" title="Mesoridazine">Mesoridazine</a></li> <li><a href="/wiki/Moperone" title="Moperone">Moperone</a></li> <li><a href="/wiki/Naranol" title="Naranol">Naranol</a></li> <li><a href="/wiki/Nemonapride" title="Nemonapride">Nemonapride</a></li> <li><a href="/wiki/Penfluridol" title="Penfluridol">Penfluridol</a></li> <li><a href="/wiki/Perathiepin" title="Perathiepin">Perathiepin</a></li> <li><a href="/wiki/Perazine" title="Perazine">Perazine</a></li> <li><a href="/wiki/Periciazine" title="Periciazine">Pericyazine (periciazine)</a></li> <li><a href="/wiki/Perphenazine" title="Perphenazine">Perphenazine</a> (<a href="/wiki/Amitriptyline/perphenazine" title="Amitriptyline/perphenazine">+amitriptyline</a>)</li> <li><a href="/w/index.php?title=Piflutixol&action=edit&redlink=1" class="new" title="Piflutixol (page does not exist)">Piflutixol (pifluthixol)</a></li> <li><a href="/wiki/Pimozide" title="Pimozide">Pimozide</a></li> <li><a href="/wiki/Pipamperone" title="Pipamperone">Pipamperone</a></li> <li><a href="/wiki/Preclamol" class="mw-redirect" title="Preclamol">Preclamol</a></li> <li><a href="/wiki/Prochlorperazine" title="Prochlorperazine">Prochlorperazine</a></li> <li><a href="/wiki/Promazine" title="Promazine">Promazine</a></li> <li><a href="/wiki/Prothipendyl" title="Prothipendyl">Prothipendyl</a></li> <li><a href="/wiki/Spiperone" title="Spiperone">Spiperone (spiroperidol)</a></li> <li><a href="/wiki/Sulforidazine" title="Sulforidazine">Sulforidazine</a></li> <li><a href="/wiki/Sulpiride" title="Sulpiride">Sulpiride</a></li> <li><a href="/wiki/Sultopride" title="Sultopride">Sultopride</a></li> <li><a href="/w/index.php?title=Teflutixol&action=edit&redlink=1" class="new" title="Teflutixol (page does not exist)">Teflutixol</a></li> <li><a href="/wiki/Thiopropazate" title="Thiopropazate">Thiopropazate</a></li> <li><a href="/wiki/Thioproperazine" title="Thioproperazine">Thioproperazine</a></li> <li><a href="/wiki/Thioridazine" title="Thioridazine">Thioridazine</a></li> <li><a href="/wiki/Thiothixene" class="mw-redirect" title="Thiothixene">Thiothixene</a></li> <li><a href="/wiki/Timiperone" title="Timiperone">Timiperone</a></li> <li><a href="/wiki/Trifluoperazine" title="Trifluoperazine">Trifluoperazine</a> (<a href="/wiki/Tranylcypromine/trifluoperazine" title="Tranylcypromine/trifluoperazine">+tranylcypromine</a>)</li> <li><a href="/wiki/Triflupromazine" title="Triflupromazine">Triflupromazine</a></li> <li><a href="/wiki/Trifluperidol" title="Trifluperidol">Trifluperidol</a></li> <li><a href="/w/index.php?title=Zetidoline&action=edit&redlink=1" class="new" title="Zetidoline (page does not exist)">Zetidoline</a></li> <li><a href="/wiki/Zuclopenthixol" title="Zuclopenthixol">Zuclopenthixol</a></li></ul> <ul><li><i>Atypical antipsychotics</i>: <a href="/wiki/Amisulpride" title="Amisulpride">Amisulpride</a></li> <li><a href="/wiki/Asenapine" title="Asenapine">Asenapine</a></li> <li><a href="/wiki/BL-1020" title="BL-1020">BL-1020</a></li> <li><a href="/wiki/Blonanserin" title="Blonanserin">Blonanserin</a></li> <li><a href="/wiki/Carpipramine" title="Carpipramine">Carpipramine</a></li> <li><a href="/w/index.php?title=Cinuperone&action=edit&redlink=1" class="new" title="Cinuperone (page does not exist)">Cinuperone</a></li> <li><a href="/wiki/Clocapramine" title="Clocapramine">Clocapramine</a></li> <li><a href="/wiki/Clorotepine" title="Clorotepine">Clorotepine</a></li> <li><a href="/wiki/Clotiapine" title="Clotiapine">Clotiapine (clothiapine)</a></li> <li><a href="/wiki/Clozapine" title="Clozapine">Clozapine</a></li> <li><a href="/wiki/Cyamemazine" title="Cyamemazine">Cyamemazine</a></li> <li><a href="/wiki/DHA-clozapine" title="DHA-clozapine">DHA-clozapine</a></li> <li><a href="/wiki/Dixyrazine" title="Dixyrazine">Dixyrazine</a></li> <li><a href="/wiki/Elopiprazole" title="Elopiprazole">Elopiprazole</a></li> <li><a href="/wiki/Flumezapine" title="Flumezapine">Flumezapine</a></li> <li><a href="/wiki/Fluperlapine" title="Fluperlapine">Fluperlapine</a></li> <li><a href="/wiki/Gevotroline" title="Gevotroline">Gevotroline</a></li> <li><a href="/wiki/Iloperidone" title="Iloperidone">Iloperidone</a></li> <li><a href="/wiki/Lurasidone" title="Lurasidone">Lurasidone</a></li> <li><a href="/wiki/Mazapertine" title="Mazapertine">Mazapertine</a></li> <li><a href="/wiki/Melperone" title="Melperone">Melperone</a></li> <li><a href="/wiki/Molindone" title="Molindone">Molindone</a></li> <li><a href="/wiki/Mosapramine" title="Mosapramine">Mosapramine</a></li> <li><a href="/wiki/Ocaperidone" title="Ocaperidone">Ocaperidone</a></li> <li><a href="/wiki/Olanzapine" title="Olanzapine">Olanzapine</a> (<a href="/wiki/Olanzapine/fluoxetine" title="Olanzapine/fluoxetine">+fluoxetine</a>)</li> <li><a href="/wiki/Paliperidone" title="Paliperidone">Paliperidone</a></li> <li><a href="/wiki/Perospirone" title="Perospirone">Perospirone</a></li> <li><a href="/wiki/Piperacetazine" title="Piperacetazine">Piperacetazine</a></li> <li><a href="/wiki/Pipotiazine" title="Pipotiazine">Pipotiazine</a></li> <li><a href="/wiki/Piquindone" title="Piquindone">Piquindone</a></li> <li><a href="/wiki/Quetiapine" title="Quetiapine">Quetiapine</a></li> <li><a href="/wiki/Remoxipride" title="Remoxipride">Remoxipride</a></li> <li><a href="/wiki/Risperidone" title="Risperidone">Risperidone</a></li> <li><a href="/wiki/Sertindole" title="Sertindole">Sertindole</a></li> <li><a href="/w/index.php?title=Tefludazine&action=edit&redlink=1" class="new" title="Tefludazine (page does not exist)">Tefludazine</a></li> <li><a href="/wiki/Tenilapine" title="Tenilapine">Tenilapine</a></li> <li><a href="/wiki/Tiospirone" title="Tiospirone">Tiospirone</a></li> <li><a href="/wiki/Veralipride" title="Veralipride">Veralipride</a></li> <li><a href="/wiki/Zicronapine" title="Zicronapine">Zicronapine</a></li> <li><a href="/wiki/Ziprasidone" title="Ziprasidone">Ziprasidone</a></li> <li><a href="/wiki/Zotepine" title="Zotepine">Zotepine</a></li></ul> <ul><li><i>Antiemetics/gastroprokinetics/sedatives</i>: <a href="/wiki/Aceprometazine" title="Aceprometazine">Aceprometazine</a></li> <li><a href="/wiki/AS-8112" title="AS-8112">AS-8112</a></li> <li><a href="/wiki/Alimemazine" title="Alimemazine">Alimemazine</a></li> <li><a href="/wiki/Alizapride" title="Alizapride">Alizapride</a></li> <li><a href="/wiki/Benzquinamide" title="Benzquinamide">Benzquinamide</a></li> <li><a href="/wiki/Bromopride" title="Bromopride">Bromopride</a></li> <li><a href="/wiki/Clebopride" title="Clebopride">Clebopride</a></li> <li><a href="/wiki/Deudomperidone" title="Deudomperidone">Deudomperidone</a></li> <li><a class="mw-selflink selflink">Domperidone</a></li> <li><a href="/wiki/Eticlopride" title="Eticlopride">Eticlopride</a></li> <li><a href="/wiki/Hydroxyzine" title="Hydroxyzine">Hydroxyzine</a></li> <li><a href="/wiki/Itopride" title="Itopride">Itopride</a></li> <li><a href="/wiki/Metoclopramide" title="Metoclopramide">Metoclopramide</a></li> <li><a href="/wiki/Metopimazine" title="Metopimazine">Metopimazine</a></li> <li><a href="/wiki/Promethazine" title="Promethazine">Promethazine</a></li> <li><a href="/wiki/Thiethylperazine" title="Thiethylperazine">Thiethylperazine</a></li> <li><a href="/wiki/Trazpiroben" title="Trazpiroben">Trazpiroben</a></li> <li><a href="/wiki/Trimethobenzamide" title="Trimethobenzamide">Trimethobenzamide</a></li></ul> <ul><li><i>Antidepressants</i>: <a href="/wiki/Amoxapine" title="Amoxapine">Amoxapine</a></li> <li><a href="/wiki/Nefazodone" title="Nefazodone">Nefazodone</a></li> <li><a href="/wiki/Opipramol" title="Opipramol">Opipramol</a></li> <li><a href="/wiki/Propiomazine" title="Propiomazine">Propiomazine</a></li> <li><a href="/wiki/Trimipramine" title="Trimipramine">Trimipramine</a></li></ul> <ul><li><i>Others</i>: <a href="/wiki/3-PPP" title="3-PPP">3-PPP</a></li> <li><a href="/wiki/Alpiropride" title="Alpiropride">Alpiropride</a></li> <li><a href="/wiki/Azapride" title="Azapride">Azapride</a></li> <li><a href="/wiki/Bromerguride" title="Bromerguride">Bromerguride</a></li> <li><a href="/wiki/Bromocriptine" title="Bromocriptine">Bromocriptine</a></li> <li><a href="/wiki/Buspirone" title="Buspirone">Buspirone</a></li> <li><a href="/wiki/Desmethoxyfallypride" title="Desmethoxyfallypride">Desmethoxyfallypride</a></li> <li><a href="/wiki/N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline" title="N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline">EEDQ</a></li> <li><a href="/wiki/F-15063" title="F-15063">F-15063</a></li> <li><a href="/wiki/Fallypride" title="Fallypride">Fallypride</a></li> <li><a href="/wiki/Fananserin" title="Fananserin">Fananserin</a></li> <li><a href="/wiki/Fenfluramine" title="Fenfluramine">Fenfluramine</a></li> <li><a href="/wiki/Iodobenzamide" title="Iodobenzamide">Iodobenzamide</a></li> <li><a href="/w/index.php?title=Isocorypalmine&action=edit&redlink=1" class="new" title="Isocorypalmine (page does not exist)">Isocorypalmine</a></li> <li><a href="/wiki/L-741,626" title="L-741,626">L-741,626</a></li> <li><a href="/wiki/L-745,870" title="L-745,870">L-745,870</a></li> <li><a href="/wiki/Levofenfluramine" title="Levofenfluramine">Levofenfluramine</a></li> <li><a href="/w/index.php?title=LEK-8829&action=edit&redlink=1" class="new" title="LEK-8829 (page does not exist)">LEK-8829</a></li> <li><a href="/wiki/Metergoline" title="Metergoline">Metergoline</a></li> <li><a href="/wiki/Metitepine" title="Metitepine">Metitepine (methiothepin)</a></li> <li><a href="/wiki/N-Methylspiperone" title="N-Methylspiperone">N-Methylspiperone</a></li> <li><a href="/wiki/Nafadotride" title="Nafadotride">Nafadotride</a></li> <li><a href="/wiki/Nuciferine" title="Nuciferine">Nuciferine</a></li> <li><a href="/wiki/PNU-99,194" title="PNU-99,194">PNU-99,194</a></li> <li><a href="/wiki/Pridopidine" title="Pridopidine">Pridopidine</a></li> <li><a href="/wiki/Raclopride" title="Raclopride">Raclopride</a></li> <li><a href="/wiki/Sarizotan" title="Sarizotan">Sarizotan</a></li> <li><a href="/wiki/SB-277,011-A" title="SB-277,011-A">SB-277,011-A</a></li> <li><a href="/w/index.php?title=Seridopidine&action=edit&redlink=1" class="new" title="Seridopidine (page does not exist)">Seridopidine</a></li> <li><a href="/wiki/Sonepiprazole" title="Sonepiprazole">Sonepiprazole</a></li> <li><a href="/wiki/Spiroxatrine" title="Spiroxatrine">Spiroxatrine</a></li> <li><a href="/wiki/Stepholidine" title="Stepholidine">Stepholidine</a></li> <li><a href="/w/index.php?title=SV-293&action=edit&redlink=1" class="new" title="SV-293 (page does not exist)">SV-293</a></li> <li><a href="/wiki/Terguride" title="Terguride">Terguride</a></li> <li><a href="/wiki/Tetrahydropalmatine" title="Tetrahydropalmatine">Tetrahydropalmatine</a></li> <li><a href="/wiki/Tiapride" title="Tiapride">Tiapride</a></li> <li><a href="/wiki/UH-232" title="UH-232">UH-232</a></li> <li><a href="/wiki/Yohimbine" title="Yohimbine">Yohimbine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><small><i><b>See also:</b> <a href="/wiki/Template:Receptor_modulators" title="Template:Receptor modulators">Receptor/signaling modulators</a></i></small></li> <li><small><i><a href="/wiki/Template:Adrenergic_receptor_modulators" title="Template:Adrenergic receptor modulators">Adrenergics</a></i></small></li> <li><small><i><a href="/wiki/Template:Serotonin_receptor_modulators" title="Template:Serotonin receptor modulators">Serotonergics</a></i></small></li> <li><small><i><a href="/wiki/Template:Monoamine_reuptake_inhibitors" title="Template:Monoamine reuptake inhibitors">Monoamine reuptake inhibitors</a></i></small></li> <li><small><i><a href="/wiki/Template:Monoamine_releasing_agents" title="Template:Monoamine releasing agents">Monoamine releasing agents</a></i></small></li> <li><small><i><a href="/wiki/Template:Monoamine_metabolism_modulators" title="Template:Monoamine metabolism modulators">Monoamine metabolism modulators</a></i></small></li> <li><small><i><a href="/wiki/Template:Monoamine_neurotoxins" class="mw-redirect" title="Template:Monoamine neurotoxins">Monoamine neurotoxins</a></i></small></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Ion_channel_modulators357" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Ion_channel_modulators" title="Template:Ion channel modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Ion_channel_modulators" title="Template talk:Ion channel modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Ion_channel_modulators" title="Special:EditPage/Template:Ion channel modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Ion_channel_modulators357" style="font-size:114%;margin:0 4em"><a href="/wiki/Channel_modulator" title="Channel modulator">Ion channel modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Calcium_channel" title="Calcium channel">Calcium</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="VDCCsTooltip_Voltage-dependent_calcium_channels424" scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Voltage-dependent_calcium_channels" class="mw-redirect" title="Voltage-dependent calcium channels"><abbr title="Voltage-dependent calcium channels">VDCCs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Voltage-dependent calcium channels</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Calcium_channel_blocker" title="Calcium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/L-type_calcium_channel" title="L-type calcium channel">L-type-selective</a>:</b> <i><a href="/wiki/Dihydropyridine" class="mw-redirect" title="Dihydropyridine">Dihydropyridines</a>:</i> <a href="/wiki/Amlodipine" title="Amlodipine">Amlodipine</a></li> <li><a href="/wiki/Aranidipine" title="Aranidipine">Aranidipine</a></li> <li><a href="/wiki/Azelnidipine" title="Azelnidipine">Azelnidipine</a></li> <li><a href="/wiki/Barnidipine" title="Barnidipine">Barnidipine</a></li> <li><a href="/wiki/Clevidipine" title="Clevidipine">Clevidipine</a></li> <li><a href="/w/index.php?title=Cronidipine&action=edit&redlink=1" class="new" title="Cronidipine (page does not exist)">Cronidipine</a></li> <li><a href="/wiki/Darodipine" title="Darodipine">Darodipine</a></li> <li><a href="/w/index.php?title=Dexniguldipine&action=edit&redlink=1" class="new" title="Dexniguldipine (page does not exist)">Dexniguldipine</a></li> <li><a href="/w/index.php?title=Elgodipine&action=edit&redlink=1" class="new" title="Elgodipine (page does not exist)">Elgodipine</a></li> <li><a href="/w/index.php?title=Elnadipine&action=edit&redlink=1" class="new" title="Elnadipine (page does not exist)">Elnadipine</a></li> <li><a href="/wiki/Felodipine" title="Felodipine">Felodipine</a></li> <li><a href="/w/index.php?title=Flordipine&action=edit&redlink=1" class="new" title="Flordipine (page does not exist)">Flordipine</a></li> <li><a href="/w/index.php?title=Furnidipine&action=edit&redlink=1" class="new" title="Furnidipine (page does not exist)">Furnidipine</a></li> <li><a href="/w/index.php?title=Iganidipine&action=edit&redlink=1" class="new" title="Iganidipine (page does not exist)">Iganidipine</a></li> <li><a href="/wiki/Isradipine" title="Isradipine">Isradipine</a></li> <li><a href="/wiki/Lacidipine" title="Lacidipine">Lacidipine</a></li> <li><a href="/w/index.php?title=Lemildipine&action=edit&redlink=1" class="new" title="Lemildipine (page does not exist)">Lemildipine</a></li> <li><a href="/wiki/Lercanidipine" title="Lercanidipine">Lercanidipine</a></li> <li><a href="/wiki/Levamlodipine" title="Levamlodipine">Levamlodipine</a></li> <li><a href="/w/index.php?title=Levniguldipine&action=edit&redlink=1" class="new" title="Levniguldipine (page does not exist)">Levniguldipine</a></li> <li><a href="/wiki/Manidipine" title="Manidipine">Manidipine</a></li> <li><a href="/wiki/Barnidipine" title="Barnidipine">Mepirodipine</a></li> <li><a href="/w/index.php?title=Mesudipine&action=edit&redlink=1" class="new" title="Mesudipine (page does not exist)">Mesudipine</a></li> <li><a href="/wiki/Nicardipine" title="Nicardipine">Nicardipine</a></li> <li><a href="/wiki/Nifedipine" title="Nifedipine">Nifedipine</a></li> <li><a href="/wiki/Niguldipine" title="Niguldipine">Niguldipine</a></li> <li><a href="/wiki/Niludipine" title="Niludipine">Niludipine</a></li> <li><a href="/wiki/Nilvadipine" title="Nilvadipine">Nilvadipine</a></li> <li><a href="/wiki/Nimodipine" title="Nimodipine">Nimodipine</a></li> <li><a href="/wiki/Nisoldipine" title="Nisoldipine">Nisoldipine</a></li> <li><a href="/wiki/Nitrendipine" title="Nitrendipine">Nitrendipine</a></li> <li><a href="/w/index.php?title=Olradipine&action=edit&redlink=1" class="new" title="Olradipine (page does not exist)">Olradipine</a></li> <li><a href="/wiki/Oxodipine" title="Oxodipine">Oxodipine</a></li> <li><a href="/w/index.php?title=Palonidipine&action=edit&redlink=1" class="new" title="Palonidipine (page does not exist)">Palonidipine</a></li> <li><a href="/wiki/Pranidipine" title="Pranidipine">Pranidipine</a></li> <li><a href="/wiki/Riodipine" title="Riodipine">Ryodipine (riodipine)</a></li> <li><a href="/w/index.php?title=Sagandipine&action=edit&redlink=1" class="new" title="Sagandipine (page does not exist)">Sagandipine</a></li> <li><a href="/w/index.php?title=Sornidipine&action=edit&redlink=1" class="new" title="Sornidipine (page does not exist)">Sornidipine</a></li> <li><a href="/w/index.php?title=Teludipine&action=edit&redlink=1" class="new" title="Teludipine (page does not exist)">Teludipine</a></li> <li><a href="/w/index.php?title=Tiamdipine&action=edit&redlink=1" class="new" title="Tiamdipine (page does not exist)">Tiamdipine</a></li> <li><a href="/w/index.php?title=Trombodipine&action=edit&redlink=1" class="new" title="Trombodipine (page does not exist)">Trombodipine</a></li> <li><a href="/w/index.php?title=Vatanidipine&action=edit&redlink=1" class="new" title="Vatanidipine (page does not exist)">Vatanidipine</a>; <i><a href="/wiki/Diltiazem" title="Diltiazem">Diltiazem</a> derivatives:</i> <a href="/wiki/Clentiazem" title="Clentiazem">Clentiazem</a></li> <li><a href="/wiki/Diltiazem" title="Diltiazem">Diltiazem</a></li> <li><a href="/w/index.php?title=Iprotiazem&action=edit&redlink=1" class="new" title="Iprotiazem (page does not exist)">Iprotiazem</a></li> <li><a href="/w/index.php?title=Nictiazem&action=edit&redlink=1" class="new" title="Nictiazem (page does not exist)">Nictiazem</a></li> <li><a href="/w/index.php?title=Siratiazem&action=edit&redlink=1" class="new" title="Siratiazem (page does not exist)">Siratiazem</a>; <i><a href="/wiki/Arylalkylamine" title="Arylalkylamine">Phenylalkylamines</a>:</i> <a href="/wiki/Anipamil" title="Anipamil">Anipamil</a></li> <li><a href="/w/index.php?title=Dagapamil&action=edit&redlink=1" class="new" title="Dagapamil (page does not exist)">Dagapamil</a></li> <li><a href="/wiki/Devapamil" title="Devapamil">Devapamil</a></li> <li><a href="/w/index.php?title=Dexverapamil&action=edit&redlink=1" class="new" title="Dexverapamil (page does not exist)">Dexverapamil</a></li> <li><a href="/wiki/Emopamil" title="Emopamil">Emopamil</a></li> <li><a href="/w/index.php?title=Etripamil&action=edit&redlink=1" class="new" title="Etripamil (page does not exist)">Etripamil</a></li> <li><a href="/wiki/Falipamil" title="Falipamil">Falipamil</a></li> <li><a href="/wiki/Gallopamil" title="Gallopamil">Gallopamil</a></li> <li><a href="/w/index.php?title=Levemopamil&action=edit&redlink=1" class="new" title="Levemopamil (page does not exist)">Levemopamil</a></li> <li><a href="/w/index.php?title=Nexopamil&action=edit&redlink=1" class="new" title="Nexopamil (page does not exist)">Nexopamil</a></li> <li><a href="/wiki/Norverapamil" title="Norverapamil">Norverapamil</a></li> <li><a href="/w/index.php?title=Ronipamil&action=edit&redlink=1" class="new" title="Ronipamil (page does not exist)">Ronipamil</a></li> <li><a href="/wiki/Tiapamil" title="Tiapamil">Tiapamil</a></li> <li><a href="/wiki/Verapamil" title="Verapamil">Verapamil</a>; <i>Others:</i> <a href="/wiki/AH-1058" title="AH-1058">AH-1058</a></li> <li><a href="/w/index.php?title=Brinazarone&action=edit&redlink=1" class="new" title="Brinazarone (page does not exist)">Brinazarone</a></li> <li><a href="/wiki/Budiodarone" title="Budiodarone">Budiodarone</a></li> <li><a href="/wiki/Celivarone" title="Celivarone">Celivarone</a></li> <li><a href="/wiki/Cyproheptadine" title="Cyproheptadine">Cyproheptadine</a></li> <li><a href="/wiki/Dronedarone" title="Dronedarone">Dronedarone</a></li> <li><a href="/wiki/Fantofarone" title="Fantofarone">Fantofarone</a></li> <li><a href="/w/index.php?title=SR-33805&action=edit&redlink=1" class="new" title="SR-33805 (page does not exist)">SR-33805</a></li> <li><a href="/wiki/Tetrahydropalmatine" title="Tetrahydropalmatine">Tetrahydropalmatine</a></li></ul> <ul><li><b><a href="/wiki/N-type_calcium_channel" title="N-type calcium channel">N-type-selective</a>:</b> <a href="/wiki/%CE%A9-Conotoxin" class="mw-redirect" title="Ω-Conotoxin">ω-Conotoxins</a></li> <li><a href="/w/index.php?title=%CE%A9-Conotoxin_GVIA&action=edit&redlink=1" class="new" title="Ω-Conotoxin GVIA (page does not exist)">ω-Conotoxin GVIA</a></li> <li><a href="/wiki/Caroverine" title="Caroverine">Caroverine</a></li> <li><a href="/w/index.php?title=Huwentoxin_XVI&action=edit&redlink=1" class="new" title="Huwentoxin XVI (page does not exist)">Huwentoxin XVI</a></li> <li><a href="/wiki/Leconotide" title="Leconotide">Leconotide (ω-conotoxin CVID)</a></li> <li><a href="/w/index.php?title=PD-173212&action=edit&redlink=1" class="new" title="PD-173212 (page does not exist)">PD-173212</a></li> <li><a href="/wiki/Ralfinamide" title="Ralfinamide">Ralfinamide</a></li> <li><a href="/wiki/Safinamide" title="Safinamide">Safinamide</a></li> <li><a href="/w/index.php?title=Z160&action=edit&redlink=1" class="new" title="Z160 (page does not exist)">Z160</a></li> <li><a href="/wiki/Ziconotide" title="Ziconotide">Ziconotide (ω-conotoxin MVIIA)</a></li></ul> <ul><li><b><a href="/wiki/P-type_calcium_channel" title="P-type calcium channel">P-type-selective</a>:</b> <a href="/w/index.php?title=%CE%A9-Agatoxin_IVA&action=edit&redlink=1" class="new" title="Ω-Agatoxin IVA (page does not exist)">ω-Agatoxin IVA</a></li> <li><a href="/w/index.php?title=%CE%A9-Agatoxin_IVB&action=edit&redlink=1" class="new" title="Ω-Agatoxin IVB (page does not exist)">ω-Agatoxin IVB</a></li></ul> <ul><li><b><a href="/wiki/R-type_calcium_channel" title="R-type calcium channel">R-type-selective</a>:</b> <a href="/wiki/SNX-482" title="SNX-482">SNX-482</a></li></ul> <ul><li><b><a href="/wiki/T-type_calcium_channel" title="T-type calcium channel">T-type-selective</a>:</b> <a href="/w/index.php?title=ABT-639&action=edit&redlink=1" class="new" title="ABT-639 (page does not exist)">ABT-639</a></li> <li><a href="/w/index.php?title=ML-218&action=edit&redlink=1" class="new" title="ML-218 (page does not exist)">ML-218</a></li> <li><a href="/wiki/Niflumic_acid" title="Niflumic acid">Niflumic acid</a></li> <li><a href="/w/index.php?title=NNC_55-0396&action=edit&redlink=1" class="new" title="NNC 55-0396 (page does not exist)">NNC 55-0396</a></li> <li><a href="/w/index.php?title=ProTx_I&action=edit&redlink=1" class="new" title="ProTx I (page does not exist)">ProTx I</a></li> <li><a href="/w/index.php?title=Z944&action=edit&redlink=1" class="new" title="Z944 (page does not exist)">Z944</a></li> <li><a href="/wiki/Zonisamide" title="Zonisamide">Zonisamide</a></li></ul> <ul><li><b>Non-selective:</b> <a href="/w/index.php?title=%CE%A9-Agatoxin_TK&action=edit&redlink=1" class="new" title="Ω-Agatoxin TK (page does not exist)">ω-Agatoxin TK</a></li> <li><a href="/w/index.php?title=%CE%A9-Conotoxin_MVIIC&action=edit&redlink=1" class="new" title="Ω-Conotoxin MVIIC (page does not exist)">ω-Conotoxin MVIIC</a></li> <li><a href="/wiki/Benidipine" title="Benidipine">Benidipine</a></li> <li><a href="/wiki/Bepridil" title="Bepridil">Bepridil</a></li> <li><a href="/wiki/Cilnidipine" title="Cilnidipine">Cilnidipine</a></li> <li><a href="/wiki/Cinnarizine" title="Cinnarizine">Cinnarizine</a></li> <li><a href="/wiki/Dotarizine" title="Dotarizine">Dotarizine</a></li> <li><a href="/wiki/Efonidipine" title="Efonidipine">Efonidipine</a></li> <li><a href="/wiki/Flunarizine" title="Flunarizine">Flunarizine</a></li> <li><a href="/wiki/Lamotrigine" title="Lamotrigine">Lamotrigine</a></li> <li><a href="/wiki/Levetiracetam" title="Levetiracetam">Levetiracetam</a></li> <li><a href="/wiki/Lomerizine" title="Lomerizine">Lomerizine</a></li> <li><a href="/wiki/Loperamide" title="Loperamide">Loperamide</a></li> <li><a href="/wiki/Mibefradil" title="Mibefradil">Mibefradil</a></li> <li><a href="/w/index.php?title=NP078585&action=edit&redlink=1" class="new" title="NP078585 (page does not exist)">NP078585</a></li> <li><a href="/wiki/Ruthenium_red" title="Ruthenium red">Ruthenium red</a></li> <li><a href="/wiki/TROX-1" title="TROX-1">TROX-1</a></li></ul> <ul><li><b><a href="/wiki/Voltage-dependent_calcium_channel#α2δ_Subunit" class="mw-redirect" title="Voltage-dependent calcium channel">α<sub>2</sub>δ subunit</a>-selective (<a href="/wiki/Gabapentinoid" title="Gabapentinoid">gabapentinoids</a>):</b> <a href="/wiki/4-Methylpregabalin" title="4-Methylpregabalin">4-Methylpregabalin</a></li> <li><a href="/wiki/Arbaclofen" class="mw-redirect" title="Arbaclofen">Arbaclofen</a></li> <li><a href="/wiki/Arbaclofen_placarbil" title="Arbaclofen placarbil">Arbaclofen placarbil</a></li> <li><a href="/wiki/Atagabalin" title="Atagabalin">Atagabalin</a></li> <li><a href="/wiki/Baclofen" title="Baclofen">Baclofen</a></li> <li><a href="/wiki/Gabapentin" title="Gabapentin">Gabapentin</a></li> <li><a href="/wiki/Gabapentin_enacarbil" title="Gabapentin enacarbil">Gabapentin enacarbil</a></li> <li><a href="/wiki/Imagabalin" title="Imagabalin">Imagabalin</a></li> <li><a href="/wiki/Mirogabalin" title="Mirogabalin">Mirogabalin</a></li> <li><a href="/w/index.php?title=PD-200,347&action=edit&redlink=1" class="new" title="PD-200,347 (page does not exist)">PD-200,347</a></li> <li><a href="/wiki/PD-217,014" title="PD-217,014">PD-217,014</a></li> <li><a href="/w/index.php?title=PD-299,685&action=edit&redlink=1" class="new" title="PD-299,685 (page does not exist)">PD-299,685</a></li> <li><a href="/wiki/Phenibut" title="Phenibut">Phenibut</a></li> <li><a href="/wiki/Pregabalin" title="Pregabalin">Pregabalin</a></li></ul> <ul><li><b>Others/unsorted:</b> <a href="/wiki/Bencyclane" title="Bencyclane">Bencyclane</a></li> <li><a href="/wiki/Berbamine" title="Berbamine">Berbamine</a></li> <li><a href="/wiki/Bevantolol" title="Bevantolol">Bevantolol</a></li> <li><a href="/wiki/Canadine" title="Canadine">Canadine</a></li> <li><a href="/wiki/Carboxyamidotriazole" title="Carboxyamidotriazole">Carboxyamidotriazole</a></li> <li><a href="/wiki/Cycleanine" title="Cycleanine">Cycleanine</a></li> <li><a href="/wiki/Dauricine" title="Dauricine">Dauricine</a></li> <li><a href="/wiki/Dimeditiapramine" class="mw-redirect" title="Dimeditiapramine">Dimeditiapramine</a></li> <li><a href="/wiki/Diproteverine" title="Diproteverine">Diproteverine</a></li> <li><a href="/wiki/Enpiperate" title="Enpiperate">Enpiperate</a></li> <li><a href="/wiki/Eperisone" title="Eperisone">Eperisone</a></li> <li><a href="/w/index.php?title=Elpetrigine&action=edit&redlink=1" class="new" title="Elpetrigine (page does not exist)">Elpetrigine</a></li> <li><a href="/wiki/Ethadione" title="Ethadione">Ethadione</a></li> <li><a href="/wiki/Alcohol_(drug)" title="Alcohol (drug)">Ethanol (alcohol)</a></li> <li><a href="/wiki/Ethosuximide" title="Ethosuximide">Ethosuximide</a></li> <li><a href="/wiki/Fasudil" title="Fasudil">Fasudil</a></li> <li><a href="/wiki/Fendiline" title="Fendiline">Fendiline</a></li> <li><a href="/wiki/Fostedil" title="Fostedil">Fostedil</a></li> <li><a href="/wiki/Imepitoin" title="Imepitoin">Imepitoin</a></li> <li><a href="/wiki/JTV-519" title="JTV-519">JTV-519</a></li> <li><a href="/wiki/Lidoflazine" title="Lidoflazine">Lidoflazine</a></li> <li><a href="/wiki/Magnesium" title="Magnesium">Magnesium</a></li> <li><a href="/wiki/Manoalide" title="Manoalide">Manoalide</a></li> <li><a href="/wiki/Mesuximide" title="Mesuximide">Mesuximide</a></li> <li><a href="/wiki/Monatepil" title="Monatepil">Monatepil</a></li> <li><a href="/wiki/Naftopidil" title="Naftopidil">Naftopidil</a></li> <li><a href="/wiki/Ochratoxin_A" title="Ochratoxin A">Ochratoxin A</a></li> <li><a href="/wiki/Osthol" title="Osthol">Osthol</a></li> <li><a href="/wiki/Otilonium_bromide" title="Otilonium bromide">Otilonium bromide</a></li> <li><a href="/wiki/Paramethadione" title="Paramethadione">Paramethadione</a></li> <li><a href="/wiki/Phensuximide" title="Phensuximide">Phensuximide</a></li> <li><a href="/wiki/Pinaverium_bromide" title="Pinaverium bromide">Pinaverium bromide</a></li> <li><a href="/wiki/Prenylamine" title="Prenylamine">Prenylamine</a></li> <li><a href="/wiki/Rhynchophylline" title="Rhynchophylline">Rhynchophylline</a></li> <li><a href="/wiki/Sesamodil" title="Sesamodil">Sesamodil</a></li> <li><a href="/wiki/Silperisone" title="Silperisone">Silperisone</a></li> <li><a href="/w/index.php?title=Sipatrigine&action=edit&redlink=1" class="new" title="Sipatrigine (page does not exist)">Sipatrigine</a></li> <li><a href="/wiki/Terodiline" title="Terodiline">Terodiline</a></li> <li><a href="/wiki/Tetrandrine" title="Tetrandrine">Tetrandrine</a></li> <li><a href="/wiki/Tolperisone" title="Tolperisone">Tolperisone</a></li> <li><a href="/wiki/Trimethadione" title="Trimethadione">Trimethadione</a></li> <li><a href="/wiki/Valperinol" title="Valperinol">Valperinol</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Calcium_channel_opener" title="Calcium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/L-type_calcium_channel" title="L-type calcium channel">L-type-selective</a>:</b> <a href="/wiki/Bay_K8644" title="Bay K8644">Bay K8644</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Potassium_channel" title="Potassium channel">Potassium</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Voltage-gated_potassium_channels" class="mw-redirect" title="Voltage-gated potassium channels"><abbr title="Voltage-gated potassium channels">VGKCs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Voltage-gated potassium channels</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_blocker" title="Potassium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/3,4-Diaminopyridine" class="mw-redirect" title="3,4-Diaminopyridine">3,4-Diaminopyridine (amifampridine)</a></li> <li><a href="/wiki/4-Aminopyridine" title="4-Aminopyridine">4-Aminopyridine (fampridine/dalfampridine)</a></li> <li><a href="/w/index.php?title=Adekalant&action=edit&redlink=1" class="new" title="Adekalant (page does not exist)">Adekalant</a></li> <li><a href="/wiki/Almokalant" title="Almokalant">Almokalant</a></li> <li><a href="/wiki/Amiodarone" title="Amiodarone">Amiodarone</a></li> <li><a href="/wiki/Azimilide" title="Azimilide">Azimilide</a></li> <li><a href="/wiki/Bretylium" title="Bretylium">Bretylium</a></li> <li><a href="/wiki/Bunaftine" title="Bunaftine">Bunaftine</a></li> <li><a href="/wiki/Charybdotoxin" title="Charybdotoxin">Charybdotoxin</a></li> <li><a href="/w/index.php?title=Clamikalant&action=edit&redlink=1" class="new" title="Clamikalant (page does not exist)">Clamikalant</a></li> <li><a href="/wiki/Conotoxin" title="Conotoxin">Conotoxins</a></li> <li><a href="/w/index.php?title=Dalazatide&action=edit&redlink=1" class="new" title="Dalazatide (page does not exist)">Dalazatide</a></li> <li><a href="/wiki/Dendrotoxin" title="Dendrotoxin">Dendrotoxin</a></li> <li><a href="/wiki/Dofetilide" title="Dofetilide">Dofetilide</a></li> <li><a href="/wiki/Dronedarone" title="Dronedarone">Dronedarone</a></li> <li><a href="/wiki/E-4031" title="E-4031">E-4031</a></li> <li><a href="/wiki/Hanatoxin" title="Hanatoxin">Hanatoxin</a></li> <li><a href="/wiki/HgeTx1" title="HgeTx1">HgeTx1</a></li> <li><a href="/wiki/HsTx1" title="HsTx1">HsTx1</a></li> <li><a href="/wiki/Ibutilide" title="Ibutilide">Ibutilide</a></li> <li><a href="/w/index.php?title=Inakalant&action=edit&redlink=1" class="new" title="Inakalant (page does not exist)">Inakalant</a></li> <li><a href="/wiki/Kaliotoxin" title="Kaliotoxin">Kaliotoxin</a></li> <li><a href="/wiki/Linopirdine" title="Linopirdine">Linopirdine</a></li> <li><a href="/wiki/Lolitrem_B" title="Lolitrem B">Lolitrem B</a></li> <li><a href="/wiki/Maurotoxin" title="Maurotoxin">Maurotoxin</a></li> <li><a href="/wiki/Nifekalant" title="Nifekalant">Nifekalant</a></li> <li><a href="/w/index.php?title=Notoxin&action=edit&redlink=1" class="new" title="Notoxin (page does not exist)">Notoxin</a></li> <li><a href="/wiki/Paxilline" title="Paxilline">Paxilline</a></li> <li><a href="/w/index.php?title=Pinokalant&action=edit&redlink=1" class="new" title="Pinokalant (page does not exist)">Pinokalant</a></li> <li><a href="/wiki/Quinidine" title="Quinidine">Quinidine</a></li> <li><a href="/w/index.php?title=ShK-186&action=edit&redlink=1" class="new" title="ShK-186 (page does not exist)">ShK-186</a></li> <li><a href="/wiki/Sotalol" title="Sotalol">Sotalol</a></li> <li><a href="/wiki/Tedisamil" title="Tedisamil">Tedisamil</a></li> <li><a href="/w/index.php?title=Terikalant&action=edit&redlink=1" class="new" title="Terikalant (page does not exist)">Terikalant</a></li> <li><a href="/wiki/Tetraethylammonium" title="Tetraethylammonium">Tetraethylammonium</a></li> <li><a href="/wiki/Vernakalant" title="Vernakalant">Vernakalant</a></li></ul> <ul><li><b><a href="/wiki/HERG" title="HERG">hERG</a> (KCNH2, K<sub>v</sub>11.1)-specific:</b> <a href="/wiki/Ajmaline" title="Ajmaline">Ajmaline</a></li> <li><a href="/wiki/Amiodarone" title="Amiodarone">Amiodarone</a></li> <li><a href="/wiki/AmmTX3" title="AmmTX3">AmmTX3</a></li> <li><a href="/wiki/Astemizole" title="Astemizole">Astemizole</a></li> <li><a href="/wiki/Azaspiracid" title="Azaspiracid">Azaspiracid</a></li> <li><a href="/wiki/AZD1305" title="AZD1305">AZD1305</a></li> <li><a href="/wiki/Azimilide" title="Azimilide">Azimilide</a></li> <li><a href="/wiki/Bedaquiline" title="Bedaquiline">Bedaquiline</a></li> <li><a href="/wiki/BeKm-1_toxin" title="BeKm-1 toxin">BeKm-1</a></li> <li><a href="/wiki/BmTx3" title="BmTx3">BmTx3</a></li> <li><a href="/wiki/BRL-32872" title="BRL-32872">BRL-32872</a></li> <li><a href="/wiki/Chlorpromazine" title="Chlorpromazine">Chlorpromazine</a></li> <li><a href="/wiki/Cisapride" title="Cisapride">Cisapride</a></li> <li><a href="/wiki/Clarithromycin" title="Clarithromycin">Clarithromycin</a></li> <li><a href="/wiki/Darifenacin" title="Darifenacin">Darifenacin</a></li> <li><a href="/wiki/Dextropropoxyphene" title="Dextropropoxyphene">Dextropropoxyphene</a></li> <li><a href="/wiki/Diallyl_trisulfide" title="Diallyl trisulfide">Diallyl trisulfide</a></li> <li><a class="mw-selflink selflink">Domperidone</a></li> <li><a href="/wiki/E-4031" title="E-4031">E-4031</a></li> <li><a href="/wiki/Ergtoxin" title="Ergtoxin">Ergtoxins</a></li> <li><a href="/wiki/Erythromycin" title="Erythromycin">Erythromycin</a></li> <li><a href="/wiki/Gigactonine" title="Gigactonine">Gigactonine</a></li> <li><a href="/wiki/Haloperidol" title="Haloperidol">Haloperidol</a></li> <li><a href="/wiki/Ketoconazole" title="Ketoconazole">Ketoconazole</a></li> <li><a href="/wiki/Norpropoxyphene" title="Norpropoxyphene">Norpropoxyphene</a></li> <li><a href="/wiki/Orphenadrine" title="Orphenadrine">Orphenadrine</a></li> <li><a href="/wiki/Pimozide" title="Pimozide">Pimozide</a></li> <li><a href="/wiki/PNU-282,987" title="PNU-282,987">PNU-282,987</a></li> <li><a href="/wiki/Promethazine" title="Promethazine">Promethazine</a></li> <li><a href="/wiki/Quinidine" title="Quinidine">Quinidine</a></li> <li><a href="/wiki/Ranolazine" title="Ranolazine">Ranolazine</a></li> <li><a href="/wiki/Roxithromycin" title="Roxithromycin">Roxithromycin</a></li> <li><a href="/wiki/Sertindole" title="Sertindole">Sertindole</a></li> <li><a href="/wiki/Solifenacin" title="Solifenacin">Solifenacin</a></li> <li><a href="/wiki/Tamulotoxin" title="Tamulotoxin">Tamulotoxin</a></li> <li><a href="/wiki/Terodiline" title="Terodiline">Terodiline</a></li> <li><a href="/wiki/Terfenadine" title="Terfenadine">Terfenadine</a></li> <li><a href="/wiki/Thioridazine" title="Thioridazine">Thioridazine</a></li> <li><a href="/wiki/Tolterodine" title="Tolterodine">Tolterodine</a></li> <li><a href="/wiki/Vanoxerine" title="Vanoxerine">Vanoxerine</a></li> <li><a href="/wiki/Vernakalant" title="Vernakalant">Vernakalant</a></li></ul> <ul><li><b><a href="/wiki/KCNQ" title="KCNQ">KCNQ (K<sub>v</sub>7)</a>-specific:</b> <a href="/wiki/Linopirdine" title="Linopirdine">Linopirdine</a></li> <li><a href="/w/index.php?title=XE-991&action=edit&redlink=1" class="new" title="XE-991 (page does not exist)">XE-991</a></li> <li><a href="/wiki/Ssm_spooky_toxin" title="Ssm spooky toxin">Spooky toxin (SsTx)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_opener" title="Potassium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/KCNQ" title="KCNQ">KCNQ (K<sub>v</sub>7)</a>-specific:</b> <a href="/wiki/Flupirtine" title="Flupirtine">Flupirtine</a></li> <li><a href="/wiki/Retigabine" title="Retigabine">Retigabine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Inwardly_rectifying_potassium_channel" class="mw-redirect" title="Inwardly rectifying potassium channel"><abbr title="Inwardly rectifying potassium channel">IRKs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Inwardly rectifying potassium channel</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_blocker" title="Potassium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/ATP-sensitive_potassium_channel" title="ATP-sensitive potassium channel"><abbr title="ATP-sensitive potassium channel">K<sub>ATP</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip ATP-sensitive potassium channel</span>-specific:</b> <a href="/wiki/Acetohexamide" title="Acetohexamide">Acetohexamide</a></li> <li><a href="/wiki/Carbutamide" title="Carbutamide">Carbutamide</a></li> <li><a href="/wiki/Chlorpropamide" title="Chlorpropamide">Chlorpropamide</a></li> <li><a href="/wiki/Glibenclamide" title="Glibenclamide">Glibenclamide (glyburide)</a></li> <li><a href="/wiki/Glibornuride" title="Glibornuride">Glibornuride</a></li> <li><a href="/wiki/Glicaramide" title="Glicaramide">Glicaramide</a></li> <li><a href="/wiki/Gliclazide" title="Gliclazide">Gliclazide</a></li> <li><a href="/wiki/Glimepiride" title="Glimepiride">Glimepiride</a></li> <li><a href="/wiki/Glipizide" title="Glipizide">Glipizide</a></li> <li><a href="/wiki/Gliquidone" title="Gliquidone">Gliquidone</a></li> <li><a href="/wiki/Glisoxepide" title="Glisoxepide">Glisoxepide</a></li> <li><a href="/wiki/Glyclopyramide" title="Glyclopyramide">Glyclopyramide</a></li> <li><a href="/w/index.php?title=Glycyclamide&action=edit&redlink=1" class="new" title="Glycyclamide (page does not exist)">Glycyclamide</a></li> <li><a href="/wiki/Metahexamide" title="Metahexamide">Metahexamide</a></li> <li><a href="/wiki/Mitiglinide" title="Mitiglinide">Mitiglinide</a></li> <li><a href="/wiki/Nateglinide" title="Nateglinide">Nateglinide</a></li> <li><a href="/wiki/Repaglinide" title="Repaglinide">Repaglinide</a></li> <li><a href="/wiki/Tolazamide" title="Tolazamide">Tolazamide</a></li> <li><a href="/wiki/Tolbutamide" title="Tolbutamide">Tolbutamide</a></li></ul> <ul><li><b><a href="/wiki/G_protein-coupled_inwardly_rectifying_potassium_channel" title="G protein-coupled inwardly rectifying potassium channel"><abbr title="G protein-coupled inwardly rectifying potassium channel">GIRK</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip G protein-coupled inwardly rectifying potassium channel</span>-specific:</b> <a href="/wiki/Barium" title="Barium">Barium</a></li> <li><a href="/wiki/Caramiphen" title="Caramiphen">Caramiphen</a></li> <li><a href="/wiki/Cloperastine" title="Cloperastine">Cloperastine</a></li> <li><a href="/wiki/Clozapine" title="Clozapine">Clozapine</a></li> <li><a href="/wiki/Dextromethorphan" title="Dextromethorphan">Dextromethorphan</a></li> <li><a href="/wiki/Ethosuximide" title="Ethosuximide">Ethosuximide</a></li> <li><a href="/wiki/Ifenprodil" title="Ifenprodil">Ifenprodil</a></li> <li><a href="/wiki/Tertiapin" title="Tertiapin">Tertiapin</a></li> <li><a href="/wiki/Tipepidine" title="Tipepidine">Tipepidine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_opener" title="Potassium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/ATP-sensitive_potassium_channel" title="ATP-sensitive potassium channel"><abbr title="ATP-sensitive potassium channel">K<sub>ATP</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip ATP-sensitive potassium channel</span>-specific:</b> <a href="/w/index.php?title=Aprikalim&action=edit&redlink=1" class="new" title="Aprikalim (page does not exist)">Aprikalim</a></li> <li><a href="/wiki/Bimakalim" title="Bimakalim">Bimakalim</a></li> <li><a href="/wiki/Cromakalim" title="Cromakalim">Cromakalim</a></li> <li><a href="/wiki/Diazoxide" title="Diazoxide">Diazoxide</a></li> <li><a href="/w/index.php?title=Emakalim&action=edit&redlink=1" class="new" title="Emakalim (page does not exist)">Emakalim</a></li> <li><a href="/wiki/Levcromakalim" class="mw-redirect" title="Levcromakalim">Levcromakalim</a></li> <li><a href="/w/index.php?title=Mazokalim&action=edit&redlink=1" class="new" title="Mazokalim (page does not exist)">Mazokalim</a></li> <li><a href="/wiki/Minoxidil" title="Minoxidil">Minoxidil</a></li> <li><a href="/wiki/Minoxidil_sulfate" title="Minoxidil sulfate">Minoxidil sulfate</a></li> <li><a href="/w/index.php?title=Naminidil&action=edit&redlink=1" class="new" title="Naminidil (page does not exist)">Naminidil</a></li> <li><a href="/wiki/Nicorandil" title="Nicorandil">Nicorandil</a></li> <li><a href="/wiki/Pinacidil" title="Pinacidil">Pinacidil</a></li> <li><a href="/w/index.php?title=Rilmakalim&action=edit&redlink=1" class="new" title="Rilmakalim (page does not exist)">Rilmakalim</a></li> <li><a href="/w/index.php?title=Sarakalim&action=edit&redlink=1" class="new" title="Sarakalim (page does not exist)">Sarakalim</a></li></ul> <ul><li><b><a href="/wiki/G_protein-coupled_inwardly_rectifying_potassium_channel" title="G protein-coupled inwardly rectifying potassium channel"><abbr title="G protein-coupled inwardly rectifying potassium channel">GIRK</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip G protein-coupled inwardly rectifying potassium channel</span>-specific:</b> <a href="/w/index.php?title=ML-297&action=edit&redlink=1" class="new" title="ML-297 (page does not exist)">ML-297 (VU0456810)</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Calcium-activated_potassium_channel" title="Calcium-activated potassium channel"><abbr title="Calcium-activated potassium channel">K<sub>Ca</sub></abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Calcium-activated potassium channel</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_blocker" title="Potassium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/BK_channel" title="BK channel">BK<sub>Ca</sub></a>-specific:</b> <a href="/wiki/Alcohol_(drug)" title="Alcohol (drug)">Ethanol (alcohol)</a></li> <li><a href="/wiki/GAL-021" class="mw-redirect" title="GAL-021">GAL-021</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_opener" title="Potassium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/BK_channel" title="BK channel">BK<sub>Ca</sub></a>-specific:</b> <a href="/wiki/Flufenamic_acid" title="Flufenamic acid">Flufenamic acid</a></li> <li><a href="/wiki/Meclofenamic_acid" title="Meclofenamic acid">Meclofenamic acid</a></li> <li><a href="/wiki/Niflumic_acid" title="Niflumic acid">Niflumic acid</a></li> <li><a href="/wiki/Nimesulide" title="Nimesulide">Nimesulide</a></li> <li><a href="/wiki/Rottlerin" title="Rottlerin">Rottlerin (mallotoxin)</a></li> <li><a href="/wiki/Tolfenamic_acid" title="Tolfenamic acid">Tolfenamic acid</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Tandem_pore_domain_potassium_channel" class="mw-redirect" title="Tandem pore domain potassium channel"><abbr title="Tandem pore domain potassium channel">K2Ps</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Tandem pore domain potassium channel</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_blocker" title="Potassium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/12-O-Tetradecanoylphorbol-13-acetate" title="12-O-Tetradecanoylphorbol-13-acetate">12-O-Tetradecanoylphorbol-13-acetate</a></li> <li><a href="/wiki/Arachidonic_acid" title="Arachidonic acid">Arachidonic acid</a></li> <li><a href="/wiki/Fluoxetine" title="Fluoxetine">Fluoxetine</a></li> <li><a href="/wiki/Norfluoxetine" class="mw-redirect" title="Norfluoxetine">Norfluoxetine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Potassium_channel_opener" title="Potassium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Riluzole" title="Riluzole">Riluzole</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Sodium_channel" title="Sodium channel">Sodium</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Voltage-gated_sodium_channels" class="mw-redirect" title="Voltage-gated sodium channels"><abbr title="Voltage-gated sodium channels">VGSCs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Voltage-gated sodium channels</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Sodium_channel_blocker" title="Sodium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><i>Antianginals:</i> <a href="/wiki/Ranolazine" title="Ranolazine">Ranolazine</a></li></ul> <ul><li><i>Antiarrhythmics (class I):</i> <a href="/wiki/Ajmaline" title="Ajmaline">Ajmaline</a></li> <li><a href="/wiki/Aprindine" title="Aprindine">Aprindine</a></li> <li><a href="/wiki/Disopyramide" title="Disopyramide">Disopyramide</a></li> <li><a href="/wiki/Dronedarone" title="Dronedarone">Dronedarone</a></li> <li><a href="/wiki/Encainide" title="Encainide">Encainide</a></li> <li><a href="/wiki/Flecainide" title="Flecainide">Flecainide</a></li> <li><a href="/wiki/Lidocaine" title="Lidocaine">Lidocaine</a></li> <li><a href="/wiki/Lorajmine" title="Lorajmine">Lorajmine</a></li> <li><a href="/wiki/Lorcainide" title="Lorcainide">Lorcainide</a></li> <li><a href="/wiki/Mexiletine" title="Mexiletine">Mexiletine</a></li> <li><a href="/wiki/Moracizine" title="Moracizine">Moricizine</a></li> <li><a href="/wiki/Pilsicainide" title="Pilsicainide">Pilsicainide</a></li> <li><a href="/wiki/Prajmaline" title="Prajmaline">Prajmaline</a></li> <li><a href="/wiki/Procainamide" title="Procainamide">Procainamide</a></li> <li><a href="/wiki/Propafenone" title="Propafenone">Propafenone</a></li> <li><a href="/wiki/Quinidine" title="Quinidine">Quinidine</a></li> <li><a href="/wiki/Sparteine" title="Sparteine">Sparteine</a></li> <li><a href="/wiki/Tocainide" title="Tocainide">Tocainide</a></li></ul> <ul><li><i>Anticonvulsants:</i> <a href="/w/index.php?title=Acetylpheneturide&action=edit&redlink=1" class="new" title="Acetylpheneturide (page does not exist)">Acetylpheneturide</a></li> <li><a href="/wiki/Carbamazepine" title="Carbamazepine">Carbamazepine</a></li> <li><a href="/wiki/Cenobamate" title="Cenobamate">Cenobamate</a></li> <li><a href="/wiki/Chlorphenacemide" title="Chlorphenacemide">Chlorphenacemide</a></li> <li><a href="/w/index.php?title=Elpetrigine&action=edit&redlink=1" class="new" title="Elpetrigine (page does not exist)">Elpetrigine</a></li> <li><a href="/wiki/Eslicarbazepine_acetate" title="Eslicarbazepine acetate">Eslicarbazepine acetate</a></li> <li><a href="/wiki/Ethotoin" title="Ethotoin">Ethotoin</a></li> <li><a href="/wiki/Fosphenytoin" title="Fosphenytoin">Fosphenytoin</a></li> <li><a href="/wiki/Lamotrigine" title="Lamotrigine">Lamotrigine</a></li> <li><a href="/wiki/Lacosamide" title="Lacosamide">Lacosamide</a></li> <li><a href="/wiki/Licarbazepine" title="Licarbazepine">Licarbazepine</a></li> <li><a href="/wiki/Mephenytoin" title="Mephenytoin">Mephenytoin</a></li> <li><a href="/wiki/Oxcarbazepine" title="Oxcarbazepine">Oxcarbazepine</a></li> <li><a href="/wiki/Oxitriptyline" title="Oxitriptyline">Oxitriptyline</a></li> <li><a href="/wiki/Phenacemide" title="Phenacemide">Phenacemide</a></li> <li><a href="/wiki/Pheneturide" title="Pheneturide">Pheneturide</a></li> <li><a href="/wiki/Phenytoin" title="Phenytoin">Phenytoin</a></li> <li><a href="/wiki/Rufinamide" title="Rufinamide">Rufinamide</a></li> <li><a href="/w/index.php?title=Sipatrigine&action=edit&redlink=1" class="new" title="Sipatrigine (page does not exist)">Sipatrigine</a></li> <li><a href="/wiki/Topiramate" title="Topiramate">Topiramate</a></li> <li><a href="/wiki/Sodium_valproate" class="mw-redirect" title="Sodium valproate">Sodium valproate</a></li> <li><a href="/wiki/Valnoctamide" title="Valnoctamide">Valnoctamide</a></li> <li><a href="/wiki/Valproate_pivoxil" title="Valproate pivoxil">Valproate pivoxil</a></li> <li><a href="/wiki/Valproate_semisodium" class="mw-redirect" title="Valproate semisodium">Valproate semisodium</a></li> <li><a href="/wiki/Valproic_acid" class="mw-redirect" title="Valproic acid">Valproic acid</a></li> <li><a href="/wiki/Valpromide" title="Valpromide">Valpromide</a></li> <li><a href="/wiki/Zonisamide" title="Zonisamide">Zonisamide</a></li></ul> <ul><li><i>Local anesthetics:</i> <a href="/wiki/3-(p-Fluorobenzoyloxy)tropane" title="3-(p-Fluorobenzoyloxy)tropane"><i>p</i>FBT</a></li> <li><a href="/wiki/Amylocaine" title="Amylocaine">Amylocaine</a></li> <li><a href="/wiki/Articaine" title="Articaine">Articaine</a></li> <li><a href="/wiki/Benzocaine" title="Benzocaine">Benzocaine</a></li> <li><a href="/wiki/Bupivacaine" title="Bupivacaine">Bupivacaine</a> (<a href="/wiki/Levobupivacaine" title="Levobupivacaine">Levobupivacaine</a>, <a href="/wiki/Ropivacaine" title="Ropivacaine">Ropivacaine</a>)</li> <li><a href="/wiki/Butacaine" title="Butacaine">Butacaine</a></li> <li><a href="/wiki/Butamben" title="Butamben">Butamben</a></li> <li><a href="/wiki/Chloroprocaine" title="Chloroprocaine">Chloroprocaine</a></li> <li><a href="/wiki/Cinchocaine" title="Cinchocaine">Cinchocaine</a></li> <li><a href="/wiki/Cocaine" title="Cocaine">Cocaine</a></li> <li><a href="/wiki/Cyclomethycaine" title="Cyclomethycaine">Cyclomethycaine</a></li> <li><a href="/wiki/Dimethocaine" title="Dimethocaine">Dimethocaine</a></li> <li><a href="/wiki/Diphenhydramine" title="Diphenhydramine">Diphenhydramine</a></li> <li><a href="/wiki/Etidocaine" title="Etidocaine">Etidocaine</a></li> <li><a href="/wiki/Hexylcaine" title="Hexylcaine">Hexylcaine</a></li> <li><a href="/wiki/Iontocaine" title="Iontocaine">Iontocaine</a></li> <li><a href="/wiki/Lidocaine" title="Lidocaine">Lidocaine</a></li> <li><a href="/wiki/Mepivacaine" title="Mepivacaine">Mepivacaine</a></li> <li><a href="/wiki/Meprylcaine" title="Meprylcaine">Meprylcaine</a></li> <li><a href="/wiki/Metabutoxycaine" title="Metabutoxycaine">Metabutoxycaine</a></li> <li><a href="/wiki/Orthocaine" title="Orthocaine">Orthocaine</a></li> <li><a href="/wiki/Piperocaine" title="Piperocaine">Piperocaine</a></li> <li><a href="/wiki/Prilocaine" title="Prilocaine">Prilocaine</a></li> <li><a href="/wiki/Procaine" title="Procaine">Procaine</a></li> <li><a href="/wiki/Propoxycaine" title="Propoxycaine">Propoxycaine</a></li> <li><a href="/wiki/Proxymetacaine" title="Proxymetacaine">Proxymetacaine</a></li> <li><a href="/wiki/Risocaine" title="Risocaine">Risocaine</a></li> <li><a href="/wiki/Tetracaine" title="Tetracaine">Tetracaine</a></li> <li><a href="/wiki/Trimecaine" title="Trimecaine">Trimecaine</a></li></ul> <ul><li><i>Analgesics:</i> <a href="/w/index.php?title=AZD-3161&action=edit&redlink=1" class="new" title="AZD-3161 (page does not exist)">AZD-3161</a></li> <li><a href="/wiki/DSP-2230" title="DSP-2230">DSP-2230</a></li> <li><a href="/wiki/Funapide" title="Funapide">Funapide</a></li> <li><a href="/w/index.php?title=GDC-0276&action=edit&redlink=1" class="new" title="GDC-0276 (page does not exist)">GDC-0276</a></li> <li><a href="/w/index.php?title=NKTR-171&action=edit&redlink=1" class="new" title="NKTR-171 (page does not exist)">NKTR-171</a></li> <li><a href="/w/index.php?title=PF-04531083&action=edit&redlink=1" class="new" title="PF-04531083 (page does not exist)">PF-04531083</a></li> <li><a href="/wiki/PF-05089771" title="PF-05089771">PF-05089771</a></li> <li><a href="/wiki/Ralfinamide" title="Ralfinamide">Ralfinamide</a></li> <li><a href="/wiki/Raxatrigine" class="mw-redirect" title="Raxatrigine">Raxatrigine</a></li> <li><a href="/w/index.php?title=RG7893&action=edit&redlink=1" class="new" title="RG7893 (page does not exist)">RG7893 (GDC-0287)</a></li> <li><a href="/wiki/Suzetrigine" title="Suzetrigine">Suzetrigine</a></li></ul> <ul><li><i>Toxins:</i> <a href="/wiki/Conotoxin" title="Conotoxin">Conotoxins</a></li> <li><a href="/wiki/Neosaxitoxin" title="Neosaxitoxin">Neosaxitoxin</a></li> <li><a href="/wiki/Saxitoxin" title="Saxitoxin">Saxitoxin</a></li> <li><a href="/wiki/Tetrodotoxin" title="Tetrodotoxin">Tetrodotoxin</a></li> <li><a href="/wiki/Zetekitoxin_AB" title="Zetekitoxin AB">Zetekitoxin AB</a></li></ul> <ul><li><i>Others:</i> <a href="/wiki/Buprenorphine" title="Buprenorphine">Buprenorphine</a></li> <li><a href="/wiki/Evenamide" title="Evenamide">Evenamide</a></li> <li><a href="/wiki/Menthol" title="Menthol">Menthol</a> (<a href="/wiki/Mentha" title="Mentha">mint</a>)</li> <li><a href="/wiki/Safinamide" title="Safinamide">Safinamide</a></li> <li><a href="/wiki/Tricyclic_antidepressant" title="Tricyclic antidepressant">Tricyclic antidepressants</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Sodium_channel_opener" title="Sodium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aconitine" title="Aconitine">Aconitine</a></li> <li>Atracotoxins (<a href="/wiki/Omega-Atracotoxin" title="Omega-Atracotoxin">ω-Atracotoxin</a>, <a href="/wiki/Robustoxin" class="mw-redirect" title="Robustoxin">Robustoxin</a>, <a href="/wiki/Versutoxin" title="Versutoxin">Versutoxin</a>)</li> <li><a href="/wiki/Batrachotoxin" title="Batrachotoxin">Batrachotoxin</a></li> <li><a href="/wiki/Ciguatoxin" title="Ciguatoxin">Ciguatoxins</a></li> <li><a href="/wiki/Grayanotoxin" title="Grayanotoxin">Grayanotoxins</a></li> <li><a href="/wiki/Poneratoxin" title="Poneratoxin">Poneratoxin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Epithelial_sodium_channel" title="Epithelial sodium channel"><abbr title="Epithelial sodium channel">ENaC</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Epithelial sodium channel</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Sodium_channel_blocker" title="Sodium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Amiloride" title="Amiloride">Amiloride</a></li> <li><a href="/wiki/Benzamil" title="Benzamil">Benzamil</a></li> <li><a href="/wiki/Triamterene" title="Triamterene">Triamterene</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Sodium_channel_opener" title="Sodium channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Solnatide&action=edit&redlink=1" class="new" title="Solnatide (page does not exist)">Solnatide</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Acid-sensing_ion_channel" title="Acid-sensing ion channel"><abbr title="Acid-sensing ion channel">ASICs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Acid-sensing ion channel</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Sodium_channel_blocker" title="Sodium channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=A-317567&action=edit&redlink=1" class="new" title="A-317567 (page does not exist)">A-317567</a></li> <li><a href="/wiki/Amiloride" title="Amiloride">Amiloride</a></li> <li><a href="/wiki/Aspirin" title="Aspirin">Aspirin</a></li> <li><a href="/wiki/Ibuprofen" title="Ibuprofen">Ibuprofen</a></li> <li><a href="/w/index.php?title=PcTX1&action=edit&redlink=1" class="new" title="PcTX1 (page does not exist)">PcTX1</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Chloride_channel" title="Chloride channel">Chloride</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Calcium-activated_chloride_channel" class="mw-redirect" title="Calcium-activated chloride channel"><abbr title="Calcium-activated chloride channel">CaCCs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Calcium-activated chloride channel</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Chloride_channel_blocker" title="Chloride channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Crofelemer" title="Crofelemer">Crofelemer</a></li> <li><a href="/wiki/DIDS" title="DIDS">DIDS</a></li> <li><a href="/wiki/Ethacrynic_acid" class="mw-redirect" title="Ethacrynic acid">Ethacrynic acid</a></li> <li><a href="/wiki/Flufenamic_acid" title="Flufenamic acid">Flufenamic acid</a></li> <li><a href="/wiki/Fluoxetine" title="Fluoxetine">Fluoxetine</a></li> <li><a href="/wiki/Furosemide" title="Furosemide">Furosemide</a></li> <li><a href="/wiki/Glibenclamide" title="Glibenclamide">Glibenclamide</a></li> <li><a href="/wiki/Mefloquine" title="Mefloquine">Mefloquine</a></li> <li><a href="/wiki/Mibefradil" title="Mibefradil">Mibefradil</a></li> <li><a href="/wiki/Niflumic_acid" title="Niflumic acid">Niflumic acid</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Chloride_channel_opener" title="Chloride channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carbachol" title="Carbachol">Carbachol</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Cystic_fibrosis_transmembrane_conductance_regulator" title="Cystic fibrosis transmembrane conductance regulator"><abbr title="Cystic fibrosis transmembrane conductance regulator">CFTR</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Cystic fibrosis transmembrane conductance regulator</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Chloride_channel_blocker" title="Chloride channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Glibenclamide" title="Glibenclamide">Glibenclamide</a></li> <li><a href="/wiki/Lonidamine" title="Lonidamine">Lonidamine</a></li> <li><a href="/wiki/Piretanide" title="Piretanide">Piretanide</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Chloride_channel_opener" title="Chloride channel opener">Activators</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=1,7-Phenanthroline&action=edit&redlink=1" class="new" title="1,7-Phenanthroline (page does not exist)">1,7-Phenanthroline</a></li> <li><a href="/wiki/1,10-Phenanthroline" title="1,10-Phenanthroline">1,10-Phenanthroline</a></li> <li><a href="/w/index.php?title=4,7-Phenanthroline&action=edit&redlink=1" class="new" title="4,7-Phenanthroline (page does not exist)">4,7-Phenanthroline</a></li> <li><a href="/w/index.php?title=7,8-Benzoquinoline&action=edit&redlink=1" class="new" title="7,8-Benzoquinoline (page does not exist)">7,8-Benzoquinoline</a></li> <li><a href="/wiki/Ivacaftor" title="Ivacaftor">Ivacaftor</a></li> <li><a href="/wiki/Phenanthridine" title="Phenanthridine">Phenanthridine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;">Unsorted</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Chloride_channel_blocker" title="Chloride channel blocker">Blockers</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bumetanide" title="Bumetanide">Bumetanide</a></li> <li><a href="/wiki/Flufenamic_acid" title="Flufenamic acid">Flufenamic acid</a></li> <li><a href="/wiki/Meclofenamic_acid" title="Meclofenamic acid">Meclofenamic acid</a></li> <li><a href="/wiki/Mefenamic_acid" title="Mefenamic acid">Mefenamic acid</a></li> <li><a href="/wiki/Mepacrine" title="Mepacrine">Mepacrine</a></li> <li><a href="/wiki/Niflumic_acid" title="Niflumic acid">Niflumic acid</a></li> <li><a href="/w/index.php?title=Talniflumate&action=edit&redlink=1" class="new" title="Talniflumate (page does not exist)">Talniflumate</a></li> <li><a href="/wiki/Tolfenamic_acid" title="Tolfenamic acid">Tolfenamic acid</a></li> <li><a href="/wiki/Trifluoperazine" title="Trifluoperazine">Trifluoperazine</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;">Others</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Transient_receptor_potential_channels" class="mw-redirect" title="Transient receptor potential channels"><abbr title="Transient receptor potential channels">TRPs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Transient receptor potential channels</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:Transient_receptor_potential_channel_modulators" title="Template:Transient receptor potential channel modulators">here</a> instead.</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:5em;;text-align:center;"><a href="/wiki/Ligand_gated_ion_channels" class="mw-redirect" title="Ligand gated ion channels"><abbr title="Ligand gated ion channels">LGICs</abbr></a><span class="sr-only" style="border: 0; clip: rect(0, 0, 0, 0); clip-path: polygon(0px 0px, 0px 0px, 0px 0px); height: 1px; margin: -1px; overflow: hidden; padding: 0; position: absolute; width: 1px; white-space: nowrap;">Tooltip Ligand gated ion channels</span></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li>See <a href="/wiki/Template:Pharmacomodulation" title="Template:Pharmacomodulation">here</a> instead.</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div><i><b>See also:</b> <a href="/wiki/Template:Receptor_modulators" title="Template:Receptor modulators">Receptor/signaling modulators</a> • <a href="/wiki/Template:Transient_receptor_potential_channel_modulators" title="Template:Transient receptor potential channel modulators">Transient receptor potential channel modulators</a></i></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Prolactin_receptor_modulators151" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Prolactin_receptor_modulators" title="Template:Prolactin receptor modulators"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Prolactin_receptor_modulators" title="Template talk:Prolactin receptor modulators"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Prolactin_receptor_modulators" title="Special:EditPage/Template:Prolactin receptor modulators"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Prolactin_receptor_modulators151" style="font-size:114%;margin:0 4em"><a href="/wiki/Prolactin_receptor" title="Prolactin receptor">Prolactin receptor</a> <a href="/wiki/Receptor_modulator" title="Receptor modulator">modulators</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Agonist" title="Agonist">Agonists</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Growth_hormone" title="Growth hormone">Growth hormone</a></li> <li><a href="/wiki/Human_placental_lactogen" title="Human placental lactogen">Human placental lactogen</a></li> <li><a href="/wiki/Placental_growth_hormone" class="mw-redirect" title="Placental growth hormone">Placental growth hormone (growth hormone variant)</a></li> <li><a href="/wiki/Prolactin" title="Prolactin">Prolactin</a></li> <li><a href="/w/index.php?title=S179D-hPRL&action=edit&redlink=1" class="new" title="S179D-hPRL (page does not exist)">S179D-hPRL</a></li> <li><a href="/wiki/Somatotropin" class="mw-redirect" title="Somatotropin">Somatotropin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Receptor_antagonist" title="Receptor antagonist">Antagonists</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=%CE%941%E2%80%939-G129R-hPRL&action=edit&redlink=1" class="new" title="Δ1–9-G129R-hPRL (page does not exist)">Δ1–9-G129R-hPRL</a></li> <li><a href="/w/index.php?title=%CE%941%E2%80%9314-G129R-hPRL&action=edit&redlink=1" class="new" title="Δ1–14-G129R-hPRL (page does not exist)">Δ1–14-G129R-hPRL</a></li> <li><a href="/w/index.php?title=G120K-hGH&action=edit&redlink=1" class="new" title="G120K-hGH (page does not exist)">G120K-hGH</a></li> <li><a href="/w/index.php?title=G129R-hPRL&action=edit&redlink=1" class="new" title="G129R-hPRL (page does not exist)">G129R-hPRL</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Prolactin_modulator" title="Prolactin modulator">Indirect<br />modulators</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Prolactin_inhibitor" class="mw-redirect" title="Prolactin inhibitor">Inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/D2_receptor" class="mw-redirect" title="D2 receptor">D<sub>2</sub> receptor</a> <a href="/wiki/Agonist" title="Agonist">agonists</a> (e.g., <a href="/wiki/Bromocriptine" title="Bromocriptine">bromocriptine</a>, <a href="/wiki/Cabergoline" title="Cabergoline">cabergoline</a>, <a href="/wiki/Lergotrile" title="Lergotrile">lergotrile</a>, <a href="/wiki/Lisuride" title="Lisuride">lisuride</a>, <a href="/wiki/Metergoline" title="Metergoline">metergoline</a>, <a href="/wiki/Pergolide" title="Pergolide">pergolide</a>, <a href="/wiki/Quinagolide" title="Quinagolide">quinagolide</a>, <a href="/wiki/Terguride" title="Terguride">terguride</a>)</li> <li>Indirect <a href="/wiki/Dopaminergic_agent" class="mw-redirect" title="Dopaminergic agent">dopaminergic agents</a> (e.g., <a href="/wiki/Levodopa" title="Levodopa">levodopa</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/Prolactin_releaser" class="mw-redirect" title="Prolactin releaser">Releasers</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/D2_receptor" class="mw-redirect" title="D2 receptor">D<sub>2</sub> receptor</a> <a href="/wiki/Receptor_antagonist" title="Receptor antagonist">antagonists</a> (e.g., <a class="mw-selflink selflink">domperidone</a>, <a href="/wiki/Metoclopramide" title="Metoclopramide">metoclopramide</a>, <a href="/wiki/Risperidone" title="Risperidone">risperidone</a>)</li> <li>Indirect <a href="/wiki/Antidopaminergic_agent" class="mw-redirect" title="Antidopaminergic agent">antidopaminergic agents</a> (e.g., <a href="/wiki/Reserpine" title="Reserpine">reserpine</a>)</li> <li><a href="/wiki/Estrogen" title="Estrogen">Estrogens</a> (e.g., <a href="/wiki/Estradiol" title="Estradiol">estradiol</a>)</li> <li><a href="/wiki/Progestogen" title="Progestogen">Progestogens</a> (e.g., <a href="/wiki/Progesterone" title="Progesterone">progesterone</a>)</li> <li><a href="/wiki/Thyrotropin-releasing_hormone" title="Thyrotropin-releasing hormone">Thyrotropin-releasing hormone</a> and <a href="/wiki/Thyrotropin-releasing_hormone_analogue" class="mw-redirect" title="Thyrotropin-releasing hormone analogue">analogues</a> (e.g., <a href="/wiki/Protirelin" class="mw-redirect" title="Protirelin">protirelin</a>, <a href="/wiki/Taltirelin" title="Taltirelin">taltirelin</a>)</li> <li><a href="/wiki/Vasoactive_intestinal_peptide" title="Vasoactive intestinal peptide">Vasoactive intestinal peptide</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div></div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r1130092004">.mw-parser-output .portal-bar{font-size:88%;font-weight:bold;display:flex;justify-content:center;align-items:baseline}.mw-parser-output .portal-bar-bordered{padding:0 2em;background-color:#fdfdfd;border:1px solid #a2a9b1;clear:both;margin:1em auto 0}.mw-parser-output .portal-bar-related{font-size:100%;justify-content:flex-start}.mw-parser-output .portal-bar-unbordered{padding:0 1.7em;margin-left:0}.mw-parser-output .portal-bar-header{margin:0 1em 0 0.5em;flex:0 0 auto;min-height:24px}.mw-parser-output .portal-bar-content{display:flex;flex-flow:row wrap;flex:0 1 auto;padding:0.15em 0;column-gap:1em;align-items:baseline;margin:0;list-style:none}.mw-parser-output .portal-bar-content-related{margin:0;list-style:none}.mw-parser-output .portal-bar-item{display:inline-block;margin:0.15em 0.2em;min-height:24px;line-height:24px}@media screen and (max-width:768px){.mw-parser-output .portal-bar{font-size:88%;font-weight:bold;display:flex;flex-flow:column wrap;align-items:baseline}.mw-parser-output .portal-bar-header{text-align:center;flex:0;padding-left:0.5em;margin:0 auto}.mw-parser-output .portal-bar-related{font-size:100%;align-items:flex-start}.mw-parser-output .portal-bar-content{display:flex;flex-flow:row wrap;align-items:center;flex:0;column-gap:1em;border-top:1px solid #a2a9b1;margin:0 auto;list-style:none}.mw-parser-output .portal-bar-content-related{border-top:none;margin:0;list-style:none}}.mw-parser-output .navbox+link+.portal-bar,.mw-parser-output .navbox+style+.portal-bar,.mw-parser-output .navbox+link+.portal-bar-bordered,.mw-parser-output .navbox+style+.portal-bar-bordered,.mw-parser-output .sister-bar+link+.portal-bar,.mw-parser-output .sister-bar+style+.portal-bar,.mw-parser-output .portal-bar+.navbox-styles+.navbox,.mw-parser-output .portal-bar+.navbox-styles+.sister-bar{margin-top:-1px}</style><div class="portal-bar noprint metadata noviewer portal-bar-bordered" role="navigation" aria-label="Portals"><span class="portal-bar-header"><a href="/wiki/Wikipedia:Contents/Portals" title="Wikipedia:Contents/Portals">Portal</a>:</span><ul class="portal-bar-content"><li class="portal-bar-item"><span class="nowrap"><span typeof="mw:File"><span><img alt="icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/20px-WHO_Rod.svg.png" decoding="async" width="8" height="19" class="mw-file-element" data-file-width="107" data-file-height="250" /></span></span> </span><a href="/wiki/Portal:Medicine" title="Portal:Medicine">Medicine</a></li></ul></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Retrieved from "<a dir="ltr" href="https://en.wikipedia.org/w/index.php?title=Domperidone&oldid=1277381409">https://en.wikipedia.org/w/index.php?title=Domperidone&oldid=1277381409</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Help:Category" title="Help:Category">Categories</a>: <ul><li><a href="/wiki/Category:Antiemetics" title="Category:Antiemetics">Antiemetics</a></li><li><a href="/wiki/Category:Antihypotensive_agents" title="Category:Antihypotensive agents">Antihypotensive agents</a></li><li><a href="/wiki/Category:Belgian_inventions" title="Category:Belgian inventions">Belgian inventions</a></li><li><a href="/wiki/Category:Chloroarenes" title="Category:Chloroarenes">Chloroarenes</a></li><li><a href="/wiki/Category:Dopamine_antagonists" title="Category:Dopamine antagonists">Dopamine antagonists</a></li><li><a href="/wiki/Category:HERG_blocker" title="Category:HERG blocker">HERG blocker</a></li><li><a href="/wiki/Category:Janssen_Pharmaceutica" title="Category:Janssen Pharmaceutica">Janssen Pharmaceutica</a></li><li><a href="/wiki/Category:Motility_stimulants" title="Category:Motility stimulants">Motility stimulants</a></li><li><a href="/wiki/Category:Peripherally_selective_drugs" title="Category:Peripherally selective drugs">Peripherally selective drugs</a></li><li><a href="/wiki/Category:Piperidines" title="Category:Piperidines">Piperidines</a></li><li><a href="/wiki/Category:Potassium_channel_blockers" title="Category:Potassium channel blockers">Potassium channel blockers</a></li><li><a href="/wiki/Category:Prolactin_releasers" title="Category:Prolactin releasers">Prolactin releasers</a></li><li><a href="/wiki/Category:Ureas" title="Category:Ureas">Ureas</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Hidden categories: <ul><li><a href="/wiki/Category:All_articles_with_dead_external_links" title="Category:All articles with dead external links">All articles with dead external links</a></li><li><a href="/wiki/Category:Articles_with_dead_external_links_from_August_2023" title="Category:Articles with dead external links from August 2023">Articles with dead external links from August 2023</a></li><li><a href="/wiki/Category:Articles_with_permanently_dead_external_links" title="Category:Articles with permanently dead external links">Articles with permanently dead external links</a></li><li><a href="/wiki/Category:Source_attribution" title="Category:Source attribution">Source attribution</a></li><li><a href="/wiki/Category:CS1_maint:_DOI_inactive_as_of_November_2024" title="Category:CS1 maint: DOI inactive as of November 2024">CS1 maint: DOI inactive as of November 2024</a></li><li><a href="/wiki/Category:Articles_with_short_description" title="Category:Articles with short description">Articles with short description</a></li><li><a href="/wiki/Category:Short_description_is_different_from_Wikidata" title="Category:Short description is different from Wikidata">Short description is different from Wikidata</a></li><li><a href="/wiki/Category:Use_dmy_dates_from_June_2024" title="Category:Use dmy dates from June 2024">Use dmy dates from June 2024</a></li><li><a href="/wiki/Category:Drugs_with_non-standard_legal_status" title="Category:Drugs with non-standard legal status">Drugs with non-standard legal status</a></li><li><a href="/wiki/Category:ECHA_InfoCard_ID_from_Wikidata" title="Category:ECHA InfoCard ID from Wikidata">ECHA InfoCard ID from Wikidata</a></li><li><a href="/wiki/Category:Drugboxes_which_contain_changes_to_watched_fields" title="Category:Drugboxes which contain changes to watched fields">Drugboxes which contain changes to watched fields</a></li><li><a href="/wiki/Category:All_articles_with_unsourced_statements" title="Category:All articles with unsourced statements">All articles with unsourced statements</a></li><li><a href="/wiki/Category:Articles_with_unsourced_statements_from_March_2022" title="Category:Articles with unsourced statements from March 2022">Articles with unsourced statements from March 2022</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> This page was last edited on 24 February 2025, at 09:27<span class="anonymous-show"> (UTC)</span>.</li> <li id="footer-info-copyright">Text is available under the <a href="/wiki/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License" title="Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License">Creative Commons Attribution-ShareAlike 4.0 License</a>; additional terms may apply. By using this site, you agree to the <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use" class="extiw" title="foundation:Special:MyLanguage/Policy:Terms of Use">Terms of Use</a> and <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy" class="extiw" title="foundation:Special:MyLanguage/Policy:Privacy policy">Privacy Policy</a>. Wikipedia® is a registered trademark of the <a rel="nofollow" class="external text" href="https://wikimediafoundation.org/">Wikimedia Foundation, Inc.</a>, a non-profit organization.</li> </ul> <ul id="footer-places"> <li id="footer-places-privacy"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy">Privacy policy</a></li> <li id="footer-places-about"><a href="/wiki/Wikipedia:About">About Wikipedia</a></li> <li id="footer-places-disclaimers"><a href="/wiki/Wikipedia:General_disclaimer">Disclaimers</a></li> <li id="footer-places-contact"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us">Contact Wikipedia</a></li> <li id="footer-places-wm-codeofconduct"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct">Code of Conduct</a></li> <li id="footer-places-developers"><a href="https://developer.wikimedia.org">Developers</a></li> <li id="footer-places-statslink"><a href="https://stats.wikimedia.org/#/en.wikipedia.org">Statistics</a></li> <li id="footer-places-cookiestatement"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement">Cookie statement</a></li> <li id="footer-places-mobileview"><a href="//en.m.wikipedia.org/w/index.php?title=Domperidone&mobileaction=toggle_view_mobile" class="noprint stopMobileRedirectToggle">Mobile view</a></li> </ul> <ul id="footer-icons" class="noprint"> <li id="footer-copyrightico"><a href="https://wikimediafoundation.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><picture><source media="(min-width: 500px)" srcset="/static/images/footer/wikimedia-button.svg" width="84" height="29"><img src="/static/images/footer/wikimedia.svg" width="25" height="25" alt="Wikimedia Foundation" lang="en" loading="lazy"></picture></a></li> <li id="footer-poweredbyico"><a href="https://www.mediawiki.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><picture><source media="(min-width: 500px)" srcset="/w/resources/assets/poweredby_mediawiki.svg" width="88" height="31"><img src="/w/resources/assets/mediawiki_compact.svg" alt="Powered by MediaWiki" lang="en" width="25" height="25" loading="lazy"></picture></a></li> </ul> </footer> </div> </div> </div> <div class="vector-header-container vector-sticky-header-container"> <div id="vector-sticky-header" class="vector-sticky-header"> <div class="vector-sticky-header-start"> <div class="vector-sticky-header-icon-start vector-button-flush-left vector-button-flush-right" aria-hidden="true"> <button class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-sticky-header-search-toggle" tabindex="-1" data-event-name="ui.vector-sticky-search-form.icon"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </button> </div> <div role="search" class="vector-search-box-vue vector-search-box-show-thumbnail vector-search-box"> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail"> <form action="/w/index.php" id="vector-sticky-search-form" class="cdx-search-input cdx-search-input--has-end-button"> <div class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia"> <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <div class="vector-sticky-header-context-bar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-sticky-header-toc" class="vector-dropdown mw-portlet mw-portlet-sticky-header-toc vector-sticky-header-toc vector-button-flush-left" > <input type="checkbox" id="vector-sticky-header-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-sticky-header-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-sticky-header-toc-label" for="vector-sticky-header-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-sticky-header-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div class="vector-sticky-header-context-bar-primary" aria-hidden="true" ><span class="mw-page-title-main">Domperidone</span></div> </div> </div> <div class="vector-sticky-header-end" aria-hidden="true"> <div class="vector-sticky-header-icons"> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-talk-sticky-header" tabindex="-1" data-event-name="talk-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbles mw-ui-icon-wikimedia-speechBubbles"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-subject-sticky-header" tabindex="-1" data-event-name="subject-sticky-header"><span class="vector-icon mw-ui-icon-article mw-ui-icon-wikimedia-article"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-history-sticky-header" tabindex="-1" data-event-name="history-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-history mw-ui-icon-wikimedia-wikimedia-history"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only mw-watchlink" id="ca-watchstar-sticky-header" tabindex="-1" data-event-name="watch-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-star mw-ui-icon-wikimedia-wikimedia-star"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-edit-sticky-header" tabindex="-1" data-event-name="wikitext-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-wikiText mw-ui-icon-wikimedia-wikimedia-wikiText"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-ve-edit-sticky-header" tabindex="-1" data-event-name="ve-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-edit mw-ui-icon-wikimedia-wikimedia-edit"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-viewsource-sticky-header" tabindex="-1" data-event-name="ve-edit-protected-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-editLock mw-ui-icon-wikimedia-wikimedia-editLock"></span> <span></span> </a> </div> <div class="vector-sticky-header-buttons"> <button class="cdx-button cdx-button--weight-quiet mw-interlanguage-selector" id="p-lang-btn-sticky-header" tabindex="-1" data-event-name="ui.dropdown-p-lang-btn-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-language mw-ui-icon-wikimedia-wikimedia-language"></span> <span>31 languages</span> </button> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive" id="ca-addsection-sticky-header" tabindex="-1" data-event-name="addsection-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbleAdd-progressive mw-ui-icon-wikimedia-speechBubbleAdd-progressive"></span> <span>Add topic</span> </a> </div> <div class="vector-sticky-header-icon-end"> <div class="vector-user-links"> </div> </div> </div> </div> </div> <div class="mw-portlet mw-portlet-dock-bottom emptyPortlet" id="p-dock-bottom"> <ul> </ul> </div> <script>(RLQ=window.RLQ||[]).push(function(){mw.config.set({"wgHostname":"mw-web.eqiad.main-78bdfcd464-7xtzt","wgBackendResponseTime":366,"wgPageParseReport":{"limitreport":{"cputime":"1.727","walltime":"2.071","ppvisitednodes":{"value":13035,"limit":1000000},"postexpandincludesize":{"value":606227,"limit":2097152},"templateargumentsize":{"value":117210,"limit":2097152},"expansiondepth":{"value":18,"limit":100},"expensivefunctioncount":{"value":7,"limit":500},"unstrip-depth":{"value":1,"limit":20},"unstrip-size":{"value":429911,"limit":5000000},"entityaccesscount":{"value":1,"limit":400},"timingprofile":["100.00% 1653.166 1 -total"," 45.50% 752.166 1 Template:Reflist"," 22.13% 365.927 1 Template:Infobox_drug"," 20.32% 335.851 51 Template:Cite_journal"," 17.69% 292.514 1 Template:Infobox"," 12.24% 202.278 2 Template:Navboxes"," 8.36% 138.279 17 Template:Cite_web"," 7.86% 129.896 10 Template:Navbox"," 6.24% 103.096 19 Template:Cite_book"," 6.11% 100.988 2 Template:Short_description"]},"scribunto":{"limitreport-timeusage":{"value":"0.892","limit":"10.000"},"limitreport-memusage":{"value":10257321,"limit":52428800}},"cachereport":{"origin":"mw-web.eqiad.main-8669bc5c8-nw4dm","timestamp":"20250318155408","ttl":2592000,"transientcontent":false}}});});</script> <script type="application/ld+json">{"@context":"https:\/\/schema.org","@type":"Article","name":"Domperidone","url":"https:\/\/en.wikipedia.org\/wiki\/Domperidone","sameAs":"http:\/\/www.wikidata.org\/entity\/Q424238","mainEntity":"http:\/\/www.wikidata.org\/entity\/Q424238","author":{"@type":"Organization","name":"Contributors to Wikimedia projects"},"publisher":{"@type":"Organization","name":"Wikimedia Foundation, Inc.","logo":{"@type":"ImageObject","url":"https:\/\/www.wikimedia.org\/static\/images\/wmf-hor-googpub.png"}},"datePublished":"2004-09-07T04:32:21Z","dateModified":"2025-02-24T09:27:37Z","image":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/0\/0c\/Domperidone-from-xtal-3D-bs-17.png","headline":"peripherally selective dopamine D2 receptor antagonist, used as an antiemetic, gastroprokinetic agent, and galactagogue"}</script> </body> </html>