CINXE.COM

<!DOCTYPE html> <html lang="en"> <head> <meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1" /> <meta charset="utf-8" /><script type="text/html" id="sf-tracking-consent-manager"> <style> /*Consent Form*/ #tracking-consent-dialog { padding: 15px; position: fixed; bottom: 0; right: 5px; width: 337px; border: 3px solid #1e82e0; border-radius: 5px 5px 0px 0px; background: rgba(255, 255, 255, .95); font-size: 16px; z-index: 999; } #tracking-consent-dialog-accept { background-color: #1e82e0; color: #fff; font-size: 16px; font-weight: 500; float: right; } .consent-close { font-weight: bold; float: right; padding: 2px 7px; right: 6px; top: 3px; cursor: pointer; font-size: 11px; position: absolute; background-color: #1e82e0; color: #fff; z-index: 999; border-radius: 50%; } @media (max-width: 767px) { #tracking-consent-dialog { width: 100%; font-size: 14px; } } </style> <div id="tracking-consent-dialog"> <div class="consent-close" onclick="TrackingConsentManager.updateUserConsent(true)">X</div> <strong>Cookie Policy</strong> <p>CII uses cookies to improve your website & conference experiences, including enhancing website navigation, personalized features & promotions, evaluating our services, and customizing content and ads based on your preferences as you browse or engage with us. By clicking "Continue" or continuing to use our site, you are agreeing to our and our partners use of cookies. See our <a href="https://www.cambridgeinnovationinstitute.com/Privacy-Policy/">Privacy Policy</a> for more information.</p> <button type="button" onclick="TrackingConsentManager.updateUserConsent(true)" id="tracking-consent-dialog-accept" class="btn btn-default">Continue</button> </div> </script><script type="text/javascript" src="/WebResource.axd?d=DzHrpQl5URXarFHAtrmzFrNeeCwCLwHK2gvGZ95fW9WnidZLXrfDlGTuxUr3l463ttkzDVh9D8Bug9pu7NHdr_V4jKJPpR5aBflu4f8Ts5edKoXW2sH8LcSZSfqlYNJ5LpoUn5WBE_fdKcz0yNVMxY3w_4XLcip6ESbZeM3DDdUqeeNFFCEiKQKGKqR186oo0&t=637922505220000000"> </script> <script src="/ScriptResource.axd?d=okuX3IVIBwfJlfEQK32K3iZZtiInnD21Q3naS01thH9-fzUaksT1ZtMUjWfsR2IfFrdwuSgx30ngwb9MjfyLwf8qicr33ktg3mwcpW2o3dsDH8d3-t4otTq9qT-5mrFfzK1f5nCn185AY5nCZScdoqJ1WOdlA_-4T4B_v3AbufPsc2J5Jr9-kOiHGAB_hap-0&t=4e1c7b51" type="text/javascript"></script><script src="/ScriptResource.axd?d=EydukmxBmDstn7gSYzQESGX1Bc6SUabUViYB9LpdmFW6eZLmGFNo26FA-YqkH5f3QjtPWjAHxth32_ExmLGGY1zv6AdaQenYAqaM29qW1bTxx1r5T--aFytKsL9IQMjnWBhhM3Ox0iMnCMCJK5xrzQardvmrid9DGkma-HwbE57flKsxZSkIFbT-h8oEIp2m0&t=4e1c7b51" type="text/javascript"></script><link href="/ResourcePackages/Bootstrap/assets/dist/css/main.min.css" rel="stylesheet" type="text/css" /><link href="/css/global.css" rel="stylesheet" type="text/css" /><link href="/css/editor.css" rel="stylesheet" type="text/css" /> <link href="//fonts.googleapis.com/css?family=Roboto:500,400,700" rel="stylesheet" type="text/css"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no" /> <meta property="og:title" content="Top Biopharma | Protein & Antibody Engineering Summit | 5-7 November 2024" /><meta property="og:description" content="As in the past, speaker participation from industry is quite strong at PEGS Europe with more than 50+ talks from Top Biopharma" /><meta property="og:image" content="https://www.pegsummiteurope.com/images/librariesprovider8/og/24/pge24-og-banner.jpg?sfvrsn=86020bc_1" /><meta property="og:url" content="https://www.pegsummiteurope.com/Top-Pharma" /><meta property="og:type" content="website" /><meta property="og:site_name" content="Pegs Summit Europe" /><link href="/css/24/pge/style-pge.css" media="all" rel="stylesheet" type="text/css" /><script type="text/javascript"> var link = document.createElement('link'); link.id = 'dynamic-favicon'; link.rel = 'shortcut icon'; link.href = '/images/librariesprovider8/template-images/21/favicon.png'; document.head.appendChild(link); </script><script type="text/javascript"> (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-MZXW9KK'); </script><meta name="Generator" content="Sitefinity 14.2.7900.0 DX" /><link rel="canonical" href="https://www.pegsummiteurope.com/Top-Pharma" /><script type="application/json" id="sf-insight-metadata"> {"contentMetadata":"{\"Id\":\"f565471a-5651-450d-8c2b-844cee81fbdd\",\"ContentType\":\"Page\",\"Title\":\"Top Biopharma\",\"CanonicalTitle\":\"Top Biopharma\",\"CanonicalUrl\":\"https://www.pegsummiteurope.com/Top-Pharma\",\"CreatedOn\":\"2018-08-01T16:36:11Z\",\"ModifiedOn\":\"2024-06-18T18:32:52Z\",\"SiteName\":\"Pegs Summit Europe\",\"PageId\":\"f565471a-5651-450d-8c2b-844cee81fbdd\"}","videosMetadata":"[]"} </script><script type="application/json" id="sf-insight-settings"> {"apiServerUrl":"https://api.insight.sitefinity.com/","apiKey":"62dc77b5-9fbc-74c6-8f79-d05463f0565e","applicationName":"CII_DEC","trackingCookieDomain":"","keepDecTrackingCookieOnTrackingConsentRejection":false,"slidingExpirationForTrackingCookie":false,"maxAgeForTrackingCookieInDays":365,"trackYouTubeVideos":true,"strategy":"Persist|False","docsHrefTestExpressions":[".*\\/docs\\/.+\\.{1}.+((\\?|\\\u0026)sfvrsn=.+){1}$",".+((\\?|\\\u0026)sf_dm_key=.+){1}$"]} </script><script type="text/javascript" src="/WebResource.axd?d=HtQyXelCu6mzSPcVcvK_BrDGcMZ2eaAwTGCTL_5l9xvo0iV9h2YYkvXanQ1uf0LidxbxWd8AzxNrppPmU7C9KnzDV98eKbg88D2zgKyY_GVq-IK4cwpq3ApmVVQHZ20G6_cSyVvbsc3d7cEOVVpoZalFAGFOo2fFcbG9u0riPX3ha1PNvfZCNU2C8dj5lXB2aevtM9BprQUEvuhENe--svD7i9F-8WutvDj5rAfLCkI1&t=637922505220000000"> </script><script src="https://cdn.insight.sitefinity.com/sdk/sitefinity-insight-client.min.3.1.7.js" async="async"> </script><link href="/Telerik.Web.UI.WebResource.axd?d=PMrIT5dOWaVYIcpFWUE4nCGcRFDqtHj8a0dT9N7jtPAWgyp5t5fff0pvXeFargWg3kuRljuyyjKW8grLvrafOr9X0kIEdj24q9AbiZ0prs7qITvLoGQxdqYfpMFPSD250&t=638482241021526486&compress=0&_TSM_CombinedScripts_=%3b%3bTelerik.Sitefinity.Resources%2c+Version%3d14.2.7900.0%2c+Culture%3dneutral%2c+PublicKeyToken%3db28c218413bdf563%3aen%3aec7772cc-ee32-478e-8437-4242283bb12f%3a7a90d6a" type="text/css" rel="stylesheet" /><title> Top Biopharma | Protein & Antibody Engineering Summit | 5-7 November 2024 </title><meta name="description" content="50+ Presentations from Top Biopharma in 2024 at PEGS Europe, the "best biologics technology meeting in Europe."" /></head> <body><form method="post" action="./top-pharma" id="aspnetForm"> <div class="aspNetHidden"> <input type="hidden" name="ctl04_TSM" id="ctl04_TSM" value="" /> <input type="hidden" name="ctl05_TSSM" id="ctl05_TSSM" value="" /> <input type="hidden" name="__EVENTTARGET" id="__EVENTTARGET" value="" /> <input type="hidden" name="__EVENTARGUMENT" id="__EVENTARGUMENT" value="" /> <input type="hidden" name="__VIEWSTATE" id="__VIEWSTATE" value="ZRfTB3cTHDlOTmENwGoCn+c8XjI5K6vdz6Z2I+w2O9Yl5DIpIOucqM299qdPuz+mbJxU9ES8dhF4lNOAIPc8XWDJCzAqEdGlq9G8U62Ruk0=" /> </div> <script type="text/javascript"> //<![CDATA[ var theForm = document.forms['aspnetForm']; if (!theForm) { theForm = document.aspnetForm; } function __doPostBack(eventTarget, eventArgument) { if (!theForm.onsubmit || (theForm.onsubmit() != false)) { theForm.__EVENTTARGET.value = eventTarget; theForm.__EVENTARGUMENT.value = eventArgument; theForm.submit(); } } //]]> </script> <script src="/WebResource.axd?d=pynGkmcFUV13He1Qd6_TZA_YQJD9xSUnUi70uTXUUGkw9zf_LlVkiouvQJnBXeCn1svgT4yxk9LfN7iuqrWtXg2&t=638459680569584809" type="text/javascript"></script> <script type="text/javascript"> //<![CDATA[ var __cultureInfo = {"name":"en","numberFormat":{"CurrencyDecimalDigits":2,"CurrencyDecimalSeparator":".","IsReadOnly":true,"CurrencyGroupSizes":[3],"NumberGroupSizes":[3],"PercentGroupSizes":[3],"CurrencyGroupSeparator":",","CurrencySymbol":"$","NaNSymbol":"NaN","CurrencyNegativePattern":0,"NumberNegativePattern":1,"PercentPositivePattern":1,"PercentNegativePattern":1,"NegativeInfinitySymbol":"-∞","NegativeSign":"-","NumberDecimalDigits":2,"NumberDecimalSeparator":".","NumberGroupSeparator":",","CurrencyPositivePattern":0,"PositiveInfinitySymbol":"∞","PositiveSign":"+","PercentDecimalDigits":2,"PercentDecimalSeparator":".","PercentGroupSeparator":",","PercentSymbol":"%","PerMilleSymbol":"‰","NativeDigits":["0","1","2","3","4","5","6","7","8","9"],"DigitSubstitution":1},"dateTimeFormat":{"AMDesignator":"AM","Calendar":{"MinSupportedDateTime":"\/Date(-62135578800000)\/","MaxSupportedDateTime":"\/Date(253402300799999)\/","AlgorithmType":1,"CalendarType":1,"Eras":[1],"TwoDigitYearMax":2029,"IsReadOnly":true},"DateSeparator":"/","FirstDayOfWeek":0,"CalendarWeekRule":0,"FullDateTimePattern":"dddd, MMMM d, yyyy h:mm:ss tt","LongDatePattern":"dddd, MMMM d, yyyy","LongTimePattern":"h:mm:ss tt","MonthDayPattern":"MMMM d","PMDesignator":"PM","RFC1123Pattern":"ddd, dd MMM yyyy HH\u0027:\u0027mm\u0027:\u0027ss \u0027GMT\u0027","ShortDatePattern":"M/d/yyyy","ShortTimePattern":"h:mm tt","SortableDateTimePattern":"yyyy\u0027-\u0027MM\u0027-\u0027dd\u0027T\u0027HH\u0027:\u0027mm\u0027:\u0027ss","TimeSeparator":":","UniversalSortableDateTimePattern":"yyyy\u0027-\u0027MM\u0027-\u0027dd HH\u0027:\u0027mm\u0027:\u0027ss\u0027Z\u0027","YearMonthPattern":"MMMM yyyy","AbbreviatedDayNames":["Sun","Mon","Tue","Wed","Thu","Fri","Sat"],"ShortestDayNames":["Su","Mo","Tu","We","Th","Fr","Sa"],"DayNames":["Sunday","Monday","Tuesday","Wednesday","Thursday","Friday","Saturday"],"AbbreviatedMonthNames":["Jan","Feb","Mar","Apr","May","Jun","Jul","Aug","Sep","Oct","Nov","Dec",""],"MonthNames":["January","February","March","April","May","June","July","August","September","October","November","December",""],"IsReadOnly":true,"NativeCalendarName":"Gregorian Calendar","AbbreviatedMonthGenitiveNames":["Jan","Feb","Mar","Apr","May","Jun","Jul","Aug","Sep","Oct","Nov","Dec",""],"MonthGenitiveNames":["January","February","March","April","May","June","July","August","September","October","November","December",""]},"eras":[1,"A.D.",null,0]};//]]> </script> <script src="/Telerik.Web.UI.WebResource.axd?_TSM_HiddenField_=ctl04_TSM&compress=0&_TSM_CombinedScripts_=%3b%3bSystem.Web.Extensions%2c+Version%3d4.0.0.0%2c+Culture%3dneutral%2c+PublicKeyToken%3d31bf3856ad364e35%3aen%3a18f1b484-bbc5-4e2e-8ca4-477603537f34%3aea597d4b%3ab25378d2" type="text/javascript"></script> <script src="/ScriptResource.axd?d=oBrf1f-DLFBYf_XnAiQIerYbp6DB1yP-XX6e2f1MfVZVh0-b8UJuYKCCtCgeTZdgs__r0fZWEGLHIbAdafwt8M9e685ZdEjP_79w8Op8pqlhtK8RVD9yvuuHQYso7wAeipQsr1KNKlxF-82gFsHvkROGzjmcQ59FFLTFjwumrh-7zfhoHiIXFsqfCwU3VcIw0&t=4e1c7b51" type="text/javascript"></script> <script src="/Telerik.Web.UI.WebResource.axd?_TSM_HiddenField_=ctl04_TSM&compress=0&_TSM_CombinedScripts_=%3b%3bTelerik.Sitefinity.Resources%3aen%3aec7772cc-ee32-478e-8437-4242283bb12f%3ab162b7a1" type="text/javascript"></script> <script src="/Frontend-Assembly/Telerik.Sitefinity.Frontend/Mvc/Scripts/Bootstrap/js/bootstrap.min.js?package=Bootstrap&v=MTQuMi43OTAwLjA%3d" type="text/javascript"></script> <script src="/js/sgs/menu-wsub.js" type="text/javascript"></script> <div class="aspNetHidden"> <input type="hidden" name="__VIEWSTATEGENERATOR" id="__VIEWSTATEGENERATOR" value="D4A931CD" /> </div><script type="text/javascript"> //<![CDATA[ Sys.WebForms.PageRequestManager._initialize('ctl00$ctl04', 'aspnetForm', [], [], [], 90, 'ctl00'); //]]> </script> <input type="hidden" name="ctl00$ctl04" id="ctl04" /> <script type="text/javascript"> //<![CDATA[ Sys.Application.setServerId("ctl04", "ctl00$ctl04"); Sys.Application._enableHistoryInScriptManager(); //]]> </script> <iframe id="__historyFrame" src="/ScriptResource.axd?d=ynxvUTwW3_d9tpdDtCfvdxsiJzzJ4Fa1mPZmDdjxOl-okT7Fcwn6WcbxF1aGI9YAbtbXfT_J9wHH8e5xoEAx7zldjFevw625-ixi63QwbdZp02rQSfrpnuPCqVWFpQf_eK_zwjjLenNtaymkAYw8EfLJV8nN-NUEX0QjFDrr-_I1" style="display:none;"> </iframe> <div> <div class="navbar navbar-default navbar-fixed-top"> <a class="navbar-brand large" href="/"></a> <div class="navbar-header"> <button type="button" class="navbar-toggle" data-toggle="collapse" data-target=".navbar-collapse"> <span class="icon-bar"></span> <span class="icon-bar"></span> <span class="icon-bar"></span> </button> </div> <div class="collapse navbar-collapse" id="bs-example-navbar-collapse-1"> <ul class="nav navbar-nav large-nav" role="menu"> <li class="dropdown"> <a href="#" class="dropdown-toggle" role="button"> Agenda </a> <ul role="menu" class="dropdown-menu"> <li class=""> <a href="/programs" target="_self">Programs</a> </li> <li class=""> <a href="/speaker-biographies" target="_self">Speaker Biographies</a> </li> <li class=""> <a href="/keynote" target="_self">Keynotes</a> </li> <li class="active"> <a href="/Top-Pharma" target="_self">Top Biopharma</a> </li> <li class=""> <a href="/short-courses" target="_self">Short Courses</a> </li> <li class=""> <a href="/PEGS-Europe-Training-Seminars" target="_self">Training Seminars</a> </li> <li class=""> <a href="/attendee-list" target="_self">Attendee List</a> </li> <li class=""> <a href="/agenda/search-agenda" target="_self">Search Agenda</a> </li> <li class=""> <a href="/testimonials" target="_self">Testimonials</a> </li> <li class=""> <a href="/networking" target="_self">Networking</a> </li> <li class=""> <a href="/archives" target="_self">Archives</a> </li> </ul> </li> <li class="dropdown"> <a href="#" class="dropdown-toggle" role="button"> Sponsor/Exhibit </a> <ul role="menu" class="dropdown-menu"> <li class=""> <a href="/sponsor" target="_self">Attendee Demographics + Event Features</a> </li> <li class=""> <a href="/sponsorship-opportunities" target="_self">Sponsorship Opportunities</a> </li> <li class=""> <a href="/sponsors" target="_self">Current Sponsors</a> </li> <li class=""> <a href="/sponsorship-prospectus-form" target="_self">Sponsorship Prospectus</a> </li> <li class=""> <a href="/docs/librariesprovider8/sponsor-and-exhibit/24/pge24-floorplan.pdf" target="_blank">Current Exhibitors/Floorplan</a> </li> <li class=""> <a href="https://www.intheorious.com/chi/pub/pge2025b_pub/" target="_blank">2025 Re-sign Floorplan</a> </li> <li class=""> <a href="/exhibit-services-schedule" target="_self">Exhibit Services/Schedule</a> </li> <li class=""> <a href="http://www.healthtech.com/Lead-Gen/" target="_blank">Lead Generation Opportunities</a> </li> </ul> </li> <li class="dropdown"> <a href="#" class="dropdown-toggle" role="button"> Downloads </a> <ul role="menu" class="dropdown-menu"> <li class=""> <a href="/brochures" target="_self">Brochures</a> </li> </ul> </li> <li class=""><a href="/travel" target="_self">Travel </a></li> <li class="dropdown"> <a href="#" class="dropdown-toggle" role="button"> Posters </a> <ul role="menu" class="dropdown-menu"> <li class=""> <a href="/posters" target="_self">Poster Information</a> </li> <li class=""> <a href="/poster-titles" target="_self">Poster Titles</a> </li> </ul> </li> <li class=""><a href="http://www.healthtech.com/press.aspx" target="_blank">Press</a></li> <li class="dropdown"> <a href="#" class="dropdown-toggle" role="button"> Register </a> <ul role="menu" class="dropdown-menu"> <li class=""> <a href="https://register.cambridgeinnovationinstitute.com/reg/pge" target="_self">Individual Pricing</a> </li> <li class=""> <a href="https://register.cambridgeinnovationinstitute.com/reg/pge/group" target="_self">Group Pricing</a> </li> <li class=""> <a href="https://register.cambridgeinnovationinstitute.com/reg/pge/ondemand" target="_self">On Demand Pricing</a> </li> </ul> </li> </ul> </div> </div> </div> <div > <div class="sf-Long-text" ><div class="mobile-header hidden-sm hidden-md hidden-lg"><a href="/"><img class="imageResize" src="/images/librariesprovider8/template-images/24/header-mob.png?sfvrsn=992d3334_1" alt="PEGS Summit Europe" /></a> </div></div> </div> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-MZXW9KK" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="main-content"> <div id="cph1" class="container internal"> <div class="row"> <div class="row" data-sf-element="Row"> <div class="col-sm-9"> <div id="Contentplaceholder1_T14051A0F003_Col00" class="sf_colsIn pad-lr" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div > <div class="sf-Long-text" ><p class="pageTitle">50+ Presentations from Top Biopharma in 2024</p><p><b>Augmenting Antibody-Drug Discovery with Deep Screening and Machine Learning</b><br /><i>Christopher Wassif, PhD, Director, Molecular Engineering & Antibody Technologies, <b>AstraZeneca</b></i></p><p><b>Chimeric Antigens Displaying GPR65 Extracellular Loops for Antibody Discovery</b><br /><i>Cécile Galmiche, PhD, Senior Scientist, Antibody Discovery, <b>UCB</b></i></p><p><b>Considerations for the Successful Development of Targeted Radiotherapies</b><br /><i>Urs B. Hagemann, PhD, Head, Targeted Radiopharmaceuticals, Research & Early Development Oncology, <b>Bayer AG</b></i></p><p><b>Exploring Non-Canonical Disulfide in Rabbit Antibody: Developability, Structure, and Engineering</b><br /><i>Wei-Ching Liang, PhD, Staff Scientist, Antibody Engineering, <b>Genentech, Inc.</b></i></p><p><b>Development of a Novel Antibody-Based Oral Factor VIII Mimetic Drug Candidate (Inno8)</b><br /><i>Jais R. Bjelke, PhD, Principal Scientist, Global Research, <b>Novo Nordisk AS</b></i></p><p><b>Enhancing Antibody Language Models with Structural Information</b><br /><i>Jinwoo Leem, PhD, Associate Director, Data Science, <b>Alchemab Therapeutics</b></i></p><p><b>Chain-Exchange and Split-Protein Technologies for the Generation of Targeted Antibody and Cytokine Prodrugs</b><br /><i>Vedran Vasic, PhD, Scientist, Pharma Research and Early Development (pRED), <b>Roche</b></i></p><p><b>Overcoming the Challenges with Raising Antibodies against STEAP2 Extracellular Domains for Targeted CAR T Cell Therapy</b><br /><i>Dewald van Dyk, PhD, Associate Director, Biologics Engineering, <b>AstraZeneca Pharmaceuticals LP</b></i></p><p><b>First-in-Human (FIH) Dose Selection for Biologic Modalities</b><br /><i>Celine Amara, Project Expert, DMPK, <b>Sanofi</b></i></p><p><b>Comparative Evaluation of Antigen Format Performance with Different Antibody Platforms</b><br /><i>Corey Smith, PhD, Principal Research Scientist, Global Biologics Protein Science, <b>AbbVie</b></i></p><p><b>Discovery Strategies for Antibodies Targeting Complex Multi-Spanning Membrane Proteins</b><br /><i>Trevor Wilkinson, PhD, Director, Biologics Engineering, <b>AstraZeneca</b></i></p><p><b>An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T Cell Function and</b> <b>Antitumour Immunity</b><br /><i>Javier Chaparro-Riggers, PhD, Executive Director, BioMedicine Design, <b>Pfizer Inc.</b></i></p><p><b>Bispecific and Trispecific T Cell Engagers for the Treatment of Hematological Malignancies</b><br /><i>Ulrike Philippar, PhD, Senior Director & Head, Oncology & Discovery Hematological Malignancies, <b>Johnson & Johnson Innovative Medicine</b></i></p><p><b>Preclinical Development of DuoBody-CD3-H101GxB7H4, a Novel CD3 Bispecific Antibody for the Treatment of Solid Cancers</b><br /><i>Marije Overdijk, PhD, Director, Team Lead Translational Research, <b>Genmab</b></i></p><p><b>High-Throughput Bispecific Antibody Production & Potential Applications within Discovery Workflows</b><br /><i>Charlotte H. Coles, PhD, Team Leader, <b>GSK</b></i></p><p><b>The Present and Future of Bispecific Antibodies for Cancer Therapy</b><br /><i>Christian Klein, PhD, Head, Oncology Programs and Department Head, Cancer Immunotherapy Discovery, Roche Innovation Center Zurich, <b>Roche Pharma Research & Early Development, pRED</b></i></p><p><b>Advancing Cancer Immunotherapy: Next-Generation T Cell Engagers Targeting CLDN6 via CD3/CD137 Binding</b><br /><i>Shinya Ishii, Senior Manager, Research Division, <b>Chugai Pharmaceutical Co. Ltd.</b></i></p><p><b>Design Meets Biology—Engineering Multispecific Modalities with Potentially Improved TI</b><br /><i>Yariv Mazor, PhD, Senior Director, R&D, Biologics Engineering, <b>AstraZeneca</b></i></p><p><b>A FAP-Targeted LTBR-Agonistic Bispecific Antibody Modulating the Tumour Microenvironment to Induce the Formation of HEV-Rich Immune Niches and Enhance CPI Efficacy</b><br /><i>Leo Kunz, PhD, Principal Scientist, <b>Roche</b></i></p><p><b>Emerging Role of Neutrophils in Anti-Tumour Immunity</b><br /><i>Rajkumar Noubade, PhD, Director, Oncology, <b>Gilead Sciences</b></i></p><p><b>De-Risking <i>in vivo</i> PK Attributes of Therapeutic Antibody Lead Panels Using High-Throughput <i>in vitro</i> Approaches as Part of Early Drug Discovery and Human Dose Prediction Strategy</b><br /><i>Jennifer Drew, Principal Investigator, <b>GlaxoSmithKline</b></i></p><p><b>Assessing and Optimising Developability for Multispecifics and Antibody-Drug Conjugates</b><br /><i>Andreas Evers, PhD, Associate Scientific Director, Antibody Discovery & Protein Engineering, Global Research & Development Discovery Technology, <b>Merck Healthcare KGaA</b></i></p><p><b>Advancing Biotherapeutic Developability: Computational Strategies across Diverse Therapeutic Modalities</b><br /><i>Goran Miličić, PhD, Senior Expert, Science & Technology, <b>Novartis</b></i></p><p><b><i>In silico</i> Developability for Biologics</b><br /><i>Isabelle Sermadiras, Associate Principal Scientist, <b>AstraZeneca</b></i></p><p><b>Insights from MAM Implementation at Roche/Genentech</b><br /><i>Alexander Buettner, PhD, Senior Scientist, Pharma Technical Development, <b>Roche</b></i></p><p><b>Unlocking the Power of Data: AbbVie's Digital Transformation Journey into CMC Biologics Development</b><br /><i>Dana I. Filoti, PhD, Associate Director of Scientific Architecture, Development Sciences Data and Digital Strategy, <b>Abbvie</b></i></p><p><b>Analytical Characterisation in ADC Discovery: Challenges & Approaches</b><br /><i>Elizabeth Love, PhD, Scientific Leader, Antibody Drug Conjugate Platform, <b>GSK</b></i></p><p><b>Development of Assay-Evaluating LINC Format of LINC-Ig</b><br /><i>Shusuke Nambu, PhD, Analytical Development Department, <b>Chugai Pharmaceutical Co. Ltd.</b></i></p><p><b>Comparison of Biosimilars and Innovative Biologics from an Analytical Perspective</b><br /><i>Sasa Vrhovec Hartman, PhD, Senior Expert, Science & Technology R&D, <b>Novartis Pharma Services Inc.</b></i></p><p><b>A Universal Tool for Stability Predictions of Biotherapeutics</b><br /><i>Heloise Quillay, PhD, Principal Scientist and Team Leader, CMC Analytics, <b>Sanofi</b></i></p><p><b>The Protein-Stabilising Capability of Surfactants against Agitation- and Surface-Induced Stresses</b><br /><i>Supriyadi Hafiz, Senior Scientist, Liquid Formulation R&D, <b>Merck Life Science KGaA</b></i></p><p><b>PS80 Oxidation Case Study: Impact of Tubing Material on Stability and Filling Accuracy of Biologic Drug Product</b><br /><i>Heloise Audat, Head, Formulation and Development Laboratory, Biologics Drug Product Development, <b>Sanofi</b></i><br /><i>Laetitia Poumarede, Drug Product Process Development Engineer, <b>Sanofi</b></i></p><p><b>Evaluating High-Concentration Solution Dynamics of Therapeutic Proteins in Biologics Research and Development</b><br /><i>Benjamin Weiche, PhD, Senior Scientist, Large Molecule Research, Biochemical & Analytical Research, <b>Roche Innovation Center Munich</b></i></p><p><b><i>In silico</i> Formulation Development for Protein-Based Therapeutics</b><br /><i>Giuseppe L. Licari, PhD, Lead Scientist, Computational Structural Biology, Global Drug Product Development—BDC, <b>Merck Serono SA</b></i></p><p><b>Learning from the Past: Use of <i>in silico</i> Models to Predict Physico-Chemical Profiles of Biotherapeutics</b><br /><i>Kannan Sankar, PhD, Senior Expert I, Data Science & Bioinformatics, <b>Novartis Institutes for Biomedical Research Inc.</b></i></p><p><b>Data Generation and Modelling in Combined Simulation and High-Throughput Screening for Biotherapeutic Formulation Development</b><br /><i>Maurizio Baldassarre, PhD, Associate Director & Head, Early Phase Drug Product Development, <b>Merck</b></i></p><p><b>Using Machine Learning to Predict Recombinant Protein Expression</b><br /><i>Sarah Caswell, PhD, Associate Principal Scientist, <b>AstraZeneca</b></i></p><p><b>Tailor-Made CHO Manufacturing Cell Lines Using Artificial Intronic miRNAs</b><br /><i>David Ausländer, PhD, Senior Principal Scientist & Group Head, Biologics Research Center, <b>Novartis AG</b></i></p><p><b>Mammalian Expression of Difficult-to-Express Proteins: Insights into BiTE Molecule Production Bottlenecks</b><br /><i>Benedikt Greck, Graduate Student, Large Molecular Discovery & Research Data Science, <b>Amgen Research Munich GmbH</b></i></p><p><b>Customisable Protein Expression</b><br /><i>Marina Fedorova, PhD, Scientific Investigator, Protein and Cellular Science, <b>GSK</b></i></p><p><b>Harnessing the Power of dPCR and NGS-Based Tools for Advanced Genetic Screening in Cell-Line</b> <b>Development</b><br /><i>Daniel Heinzelmann, Process Expert, Cell Line Development, <b>Boehringer Ingelheim Pharma GmbH & Co. KG</b></i></p><p><b>Using Stable Producer Cell Lines for Manufacturing of Lentiviral Vectors</b><br /><i>Jessica Vogel, Associate Scientist, BPD VVPD, <b>CSL Innovation GmbH</b></i></p><p><b>A Generic Approach for Miniaturised Unbiased Bispecific Antibody Screening via Automated Intein- or cFAE-Based Workflows</b><br /><i>Achim Doerner, PhD, Associate Director, Antibody Discovery & Protein Engineering, <b>Merck Healthcare KGaA</b></i></p><p><b>Accelerating Drug Discovery: High-Throughput Semi-Automated Expression Platform for Antibody Lead</b> <b>Generation</b><br /><i>Lucy Holt, PhD, Director, Large Molecule Discovery, <b>GSK</b></i></p><p><b>High-Throughput Analytics: Shaping Data-Driven Decisions in Biopharmaceutical Development</b><br /><i>Giulia Lambiase, PhD, Senior Scientist, Biopharmaceutical Development, <b>AstraZeneca</b></i></p><p><b>Scalable Active Learning for Therapeutic Antibody Design</b><br /><i>Nathan Frey, PhD, Senior Machine Learning Scientist, Prescient Design, <b>a Genentech Company</b></i></p><p><b>IBM Collaboration to Advance Generative AI and Foundation Models for Therapeutic Antibody Development</b><br /><i>Kausheek Nandy, Digital Transformation-Research, <b>Boehringer Ingelheim Pharmaceuticals Inc.</b></i></p><p><b>Pioneering Data-Driven Strategies in <i>de novo</i> Nanobody Design</b><br /><i>Roberto Spreafico, PhD, Director, Discovery Data Science, <b>Genmab</b></i></p><p><b>Antibody CDR Design by Ensembling Inverse Folding with Protein Language Models</b><br /><i>Diego Del Alamo, PhD, Computational Biologist, <b>GSK</b></i></p><p><b>Improved Antibody-Antigen Interaction Prediction Using Inverse Folding Latent Representations</b><br /><i>Paolo Marcatili, PhD, Director, Antibody Design, <b>Novo Nordisk</b></i></p><p><b>Preclinical Efficacy and Safety of a Novel Anti-CEA TOPO1i ADC M9140</b><br /><i>Min Shan, PhD, Medicinal Chemist, Targeted Therapeutics, <b>Merck KGaA</b></i></p><p><b>CEACAM5C, a Novel Topoisomerase I Inhibitor Antibody-Drug Conjugate Targeting CEACAM5 with High Preclinical Anti-Tumour Activity in CRC, PDAC, GC, and Lung Cancer Tumour Models</b><br /><i>Yves Baudat, Senior Scientist, Immuno Oncology, <b>Sanofi</b></i></p><p><b>Format Matters for ADCs: Generation of Binder-Format-Payload Conjugate Matrices by Antibody Chain Exchange</b><br /><i>Ulrich Brinkmann, PhD, Expert Scientist, Pharma Research & Early Development, <b>Roche Innovation Center, Munich</b></i></p><p class="pageTitle"> </p><p class="Header_Shaded"><i><b>* As of 18 June. Please see individual agenda pages for most up-to-date agenda.</b></i></p></div> </div></div> </div> <div class="col-sm-3"> <div id="Contentplaceholder1_T14051A0F003_Col01" class="sf_colsIn pad-lr" data-sf-element="Column 2" data-placeholder-label="Column 2"><div class='sfContentBlock'><br class="hidden-md hidden-lg" /><p class="social-icons"><a target="_blank" href="/docs/librariesprovider8/ics/24/pge24.ics?sfvrsn=72f8204e_1&download=true" title="Outlook"><img src="/images/default-source/social/calendar-gray.png?sfvrsn=91696e36_6" title="Outlook" alt="Outlook" class="social-icon" /></a> <a href="https://www.facebook.com/PEGSummit" target="_blank" title="Facebook"><img src="/images/default-source/social/facebook-gray.png?sfvrsn=35d4a48c_4" title="Facebook" alt="Facebook" class="social-icon" /></a> <a href="https://www.linkedin.com/groups/1830195/" target="_blank" title="LinkedIn"><img src="/images/default-source/social/linkedin-gray.png?sfvrsn=ed70471e_4" title="LinkedIn" alt="LinkedIn" class="social-icon" /></a> <a href="https://twitter.com/PEGSboston" target="_blank" title="Twitter"><img src="/images/default-source/social/twitter-gray.png?sfvrsn=bac909e7_7" title="Twitter" alt="Twitter" class="social-icon" /></a> </p><div class="sidebar-hashtag"><b>#PEGSEurope</b> </div><hr /><div><a href="https://register.cambridgeinnovationinstitute.com/reg/pge"><img src="/images/librariesprovider8/home/24/register-today-rc.png?sfvrsn=a325bb55_8" class="imageResize" alt="Register Early for Maximum Savings" /></a></div><div class="sidebar-item"><a href="/2024-brochure-download-form"><img src="/images/librariesprovider8/home/24/download-brochure-rc.png?sfvrsn=7062d93b_2" class="imageResize" alt="Download Brochure" /></a></div><div class="sidebar-item"><a href="/search"><img src="/images/librariesprovider8/home/24/search-agenda-rc.png?sfvrsn=a6f56dd7_5" class="imageResize" alt="Download Brochure" /></a></div><div class="sidebar-item"><a href="/poster-titles"><img src="/images/librariesprovider8/home/24/poster-rc.png?sfvrsn=8290ae8c_2" class="imageResize" alt="Present a poster" /></a></div><hr /> <div class="text-center"><a href="/sponsors" data-sf-ec-immutable=""><b>VIEW ALL SPONSORS</b></a> <div class="text-center pad-top"><a href="/media-partners" data-sf-ec-immutable=""><b>VIEW MEDIA PARTNERS</b></a> </div><hr /></div> </div> <div > <div class="sf-Long-text" ><p class="secondary-text"><b>Conference Programs</b></p><img src="/images/librariesprovider8/home/24/pge-icons_pge-engineering-eyebrow.png?sfvrsn=4c94b9a4_1" title="Engineering" alt="Engineering" class="imageResize" /><div><ul><li><a href="/phage-display" data-sf-ec-immutable="">Display of Biologics</a> </li><li><a href="/engineering-antibodies" data-sf-ec-immutable="">Engineering Antibodies</a> </li><li><a href="/machine-learning-part2" data-sf-ec-immutable="">Machine Learning: Part 2</a> </li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-targets-eyebrow.png?sfvrsn=aeecb1c6_1" title="Targets" alt="Targets" class="imageResize" /><ul><li><a href="/antibody-based-cancer-therapies" data-sf-ec-immutable="">Antibody-Based Therapies</a> </li><li><a href="/emerging-targets" data-sf-ec-immutable="">Emerging Targets & Approaches</a> </li><li><a href="/membrane-proteins" data-sf-ec-immutable="">Membrane Protein Targets</a> </li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-bispecifics-eyebrow.png?sfvrsn=1815c3ef_1" title="Bispecifics" alt="Bispecifics" class="imageResize" /><ul><li><a href="/bispecific-safety-efficacy" data-sf-ec-immutable="">Safety & Efficacy</a> </li><li><a href="/advancing-bispecifics" data-sf-ec-immutable="">Advancing Multispecifics</a> </li><li><a href="/engineering-bispecifics" data-sf-ec-immutable="">Engineering Bispecifics</a> </li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-immunotherapy-eyebrow.png?sfvrsn=ff126dc9_1" title="Immunotherapy" alt="Immunotherapy" class="imageResize" /><ul><li><a href="/tumour-microenvironment" data-sf-ec-immutable="">Modulating the TME</a> </li><li><a href="/car-t-innovations" data-sf-ec-immutable="">Innovative CAR T Therapy</a> </li><li><a href="/next-generation-immunotherapies" data-sf-ec-immutable="">Next-Gen Immunotherapies</a> </li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-analytical-eyebrow.png?sfvrsn=c472cb2c_1" title="Analytical" alt="Analytical" class="imageResize" /><ul><li><a href="/optimisation-developability" data-sf-ec-immutable="">Optimisation & Developability</a> </li><li><a href="/characterising-biotherapeutics" data-sf-ec-immutable="">Analytical Characterisation</a> </li><li><a href="/protein-stability" data-sf-ec-immutable="">Protein Stability & Formulation </a> </li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-expression-eyebrow.png?sfvrsn=ea1913a9_1" title="Expression" alt="Expression" class="imageResize" /><ul><li><a href="/systems-engineering" data-sf-ec-immutable="">Data Science & Engineering</a></li><li><a href="/optimising-protein-expression" data-sf-ec-immutable="">Optimising Expression</a></li><li><a href="/protein-process-development" data-sf-ec-immutable="">Process Development</a></li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-machine-learning-eyebrow.png?sfvrsn=b0bed8ca_1" class="imageResize" alt="Machine Learning" /><ul><li><a href="/PEGS-Europe-Training-Seminars" data-sf-ec-immutable="">Intro to Machine Learning</a> </li><li><a href="/machine-learning" data-sf-ec-immutable="">Machine Learning: Part 1</a> </li><li><a href="/machine-learning-part2" data-sf-ec-immutable="">Machine Learning: Part 2</a> </li></ul><img src="/images/librariesprovider8/home/24/pge-icons_pge-oncology-eyebrow.png?sfvrsn=abc93b1e_1" class="imageResize" alt="Oncology" /><ul><li><a href="/antibody-based-cancer-therapies" data-sf-ec-immutable="">Antibody-Based Therapies</a> </li><li><a href="/engineering-conjugates" data-sf-ec-immutable="">Engineering Conjugates</a> </li><li><a href="/next-generation-immunotherapies" data-sf-ec-immutable="">Next-Gen Immunotherapies</a> </li></ul><hr /><div><a href="/short-courses"><img src="/images/librariesprovider8/home/24/short-courses.png?sfvrsn=87846383_1" class="imageResize" alt="Short Courses" /></a></div><div class="sidebar-item"><a href="/PEGS-Europe-Training-Seminars"><img src="/images/librariesprovider8/home/24/training-seminars.png?sfvrsn=3cd22bc9_1" class="imageResize" alt="Training Seminars" /></a></div><hr /><p class="terciary-text text-center"><b>Related Event</b></p><a href="https://www.biologicsummit.com/" target="_blank"><img src="/images/librariesprovider8/side-bar/24/aibp25-400x175.jpg?sfvrsn=8c29de38_1" class="imageResize" alt="Bioloigics Summit 2025 - San Diego, CA" /></a> </div></div> </div></div> </div> </div> </div> </div> </div> <footer> <div > <div class="sf-Long-text" ><a href="https://register.cambridgeinnovationinstitute.com/reg/pge"><img src="/images/librariesprovider8/home/24/pge-banner-cta-final-days-1920x85.jpg?sfvrsn=7480aa37_8" alt="Register" class="imageResize" /></a></div> </div> <div > <div class="sf-Long-text" ><div class="footer"><div class="container"><div class="row"><div class="col-sm-3 col-xs-12"><div class="footer-small"><div class="footer-small-inner"><img alt="CHI | Cambridge HealthTech Institute" class="CII-footer" src="/UploadedImages/CHI-logo.png" data-sf-ec-immutable="" /><br /><p>250 First Avenue, Suite 300<br />Needham, MA 02494<br /><br />P: 781.972.5400<br />F: 781.972.5425 <br />E: <a href="mailto:chi@healthtech.com?cdtConferenceId=404272006.1663694140&cdtRollupId=404272006.1663694140" data-sf-ec-immutable="">chi@healthtech.com</a> </p><div class="row"><div class="col-sm-12 footer-social"><a href="https://twitter.com/CHI_Healthtech" data-sf-ec-immutable=""><img src="/images/default-source/social/twitter-gray.png?sfvrsn=bac909e7_7" alt="" class="footer-social-icons" /></a> <a href="https://www.linkedin.com/company/cambridge-healthtech-institute" data-sf-ec-immutable=""><img src="/images/default-source/social/linkedin-gray.png?sfvrsn=ed70471e_4" class="footer-social-icons" alt="" /></a> <a href="https://www.facebook.com/HealthtechConferences" data-sf-ec-immutable=""><img src="/images/default-source/social/facebook-gray.png?sfvrsn=35d4a48c_4" class="footer-social-icons" alt="" /></a> </div></div></div></div></div><div class="col-sm-4 footer-border hidden-xs"><div class="row"><div class="col-sm-12"><p>Life Science Portals</p></div><div class="col-sm-6"><p><a href="http://biologicaltherapeutics.cambridgeinnovationinstitute.com/home">Biological Therapeutic Products</a></p><p><a href="http://biomarkers.cambridgeinnovationinstitute.com/home">Biomarkers & Diagnostics</a></p><p><a href="http://biopharmastrategy.cambridgeinnovationinstitute.com/home">Biopharma Strategy</a></p><p><a href="https://bioprocessing.cambridgeinnovationinstitute.com/home">Bioprocess & Manufacturing</a></p><p><a href="http://chemistry.cambridgeinnovationinstitute.com/home">Chemistry</a></p><p><a href="http://clinicaltrials.cambridgeinnovationinstitute.com/home">Clinical Trials &<br data-sf-ec-immutable="" />Translational Medicine</a></p><p><a href="http://druganddevice.cambridgeinnovationinstitute.com/home">Drug & Device Safety</a></p></div><div class="col-sm-6"><p><a href="http://drugdevelopment.cambridgeinnovationinstitute.com/home">Drug Discovery & Development</a></p><p><a href="http://drugtargets.cambridgeinnovationinstitute.com/home">Drug Targets</a></p><p><a href="http://healthcare.cambridgeinnovationinstitute.com/home">Healthcare</a></p><p><a href="http://it.cambridgeinnovationinstitute.com/home">IT, AI, ML & Informatics</a></p><p><a href="http://techtools.cambridgeinnovationinstitute.com/home">Technology & Tools For<br data-sf-ec-immutable="" />Life Science</a></p><p><a href="http://therapeutics.cambridgeinnovationinstitute.com/home">Therapeutic Indications</a></p><p><a href="https://www.cambridgeinnovationinstitute.com/vip-series" data-sf-ec-immutable="">Venture, Innovation & Partnering</a></p></div></div></div><div class="col-sm-3 footer-border hidden-xs"><p>CHI Divisions</p><p><a href="https://www.healthtech.com/?cdtConferenceId=404272006.1663694140&cdtRollupId=404272006.1663694140" data-sf-ec-immutable="">Conferences</a></p><p><a href="https://www.insightpharmareports.com/" data-sf-ec-immutable="">Reports & Market Research</a></p><p><a href="https://www.barnettinternational.com/" data-sf-ec-immutable="">Barnett Educational Services</a></p><p><a href="https://www.healthtech.com/publishing" data-sf-ec-immutable="">News & Advertising</a></p><p><a href="https://proservices.healthtech.com/?cdtConferenceId=404272006.1663694140&cdtRollupId=404272006.1663694140" data-sf-ec-immutable="">Professional Services</a></p></div><div class="col-sm-2 footer-border hidden-xs"><p>Corporate Information</p><p><a href="https://www.cambridgeinnovationinstitute.com/" data-sf-ec-immutable="">Cambridge Innovation<br />Institute</a></p><p><a href="https://www.cambridgeinnovationinstitute.com/Executive-Team/" data-sf-ec-immutable="">Executive Team</a></p><p><a href="https://www.cambridgeinnovationinstitute.com/Testimonials/" data-sf-ec-immutable="">Testimonials</a></p><p><a href="https://www.cambridgeinnovationinstitute.com/mailing-list.html" data-sf-ec-immutable="">Mailing List</a></p><p><a href="https://www.cambridgeinnovationinstitute.com/Careers/" title="Careers" data-sf-ec-immutable="">Careers</a></p><hr /><p><a href="https://www.cambridgeinnovationinstitute.com/request-information" data-sf-ec-immutable="">Request Information</a></p><p><a href="https://www.cambridgeinnovationinstitute.com/Privacy-Policy/" data-sf-ec-immutable="">Privacy Policy</a></p></div></div></div></div></div> </div> </footer> <script type="text/javascript"> //<![CDATA[ window.__TsmHiddenField = $get('ctl04_TSM');;(function() { function loadHandler() { var hf = $get('ctl05_TSSM'); if (!hf._RSSM_init) { hf._RSSM_init = true; hf.value = ''; } hf.value += ';Telerik.Sitefinity.Resources, Version=14.2.7900.0, Culture=neutral, PublicKeyToken=b28c218413bdf563:en:ec7772cc-ee32-478e-8437-4242283bb12f:7a90d6a'; Sys.Application.remove_load(loadHandler); }; Sys.Application.add_load(loadHandler); })();//]]> </script> </form><script type="application/json" id="PersonalizationTracker"> {"IsPagePersonalizationTarget":false,"IsUrlPersonalizationTarget":false,"PageId":"f565471a-5651-450d-8c2b-844cee81fbdd"} </script><script type="text/javascript" src="/WebResource.axd?d=Oiw5o8i74rDb2VpVaCaMSouKRnJ2rn_cgRr8eXgFzWmU6yVv8fmvjGNlDReMboLSikSmK5y_KsDt9j-18b7ZqBNiz0-92AjY43-6qMcq4O__3MjW1Pd6kS68TTYuxCxnF4HnqcusO3ivgfHZzR9usujs8YAzvYku29ledrs3mezPir5ikBP0Pxh4nDmiJEk2WgW0YVPdsdMlu69MVd6jI94nvC3-40pMaRxtm9HTV2I1&t=637922505260000000"> </script><script type="text/javascript" src="/bower_components/js-url/url.min.js"></script><script type="text/javascript" src="/js/TrackClicks.js"></script><script type="text/javascript" src="/js/CrossDomainClient.js"></script></body> </html>