Official KEVZARA Site for HCPs and Patients| KEVZARA庐 (sarilumab) injection 200 mg

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lg:-mx-0 lg:py-0"> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="mt-3"> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 items-center self-auto bg-transparent" x-data="" dir="ltr"> <section id="bc8bcbfb-ee6d-4a96-aea9-f611ff6d5052" class="contentGridItem--bc8bcbfb-ee6d-4a96-aea9-f611ff6d5052 contentGridItem relative h-full " > <div x-data='anchorMenu()' class="h-full" x-intersect.margin.-50%='setActiveLinkByID("bc8bcbfb-ee6d-4a96-aea9-f611ff6d5052");'> <div class="contentGridItem__container relative h-full" dir="ltr"> <div class="background--bc8bcbfb-ee6d-4a96-aea9-f611ff6d5052 py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 text-primary h-full animateImage bg-transparent relative z-10"> <div class="ContentGrid container mx-auto "> <div class="flex md:flex md:flex-row lg:flex-row flex-wrap justify-center items-center -mx-0 py-0 md:-mx-0 md:py-0 lg:-mx-0 lg:py-0"> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full md:w-full lg:w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-4 items-center self-auto bg-transparent" x-data="" dir="ltr"> <section id="9de6b80c-1e35-44a8-a3ca-4b5753eec733" class="contentGridItem--9de6b80c-1e35-44a8-a3ca-4b5753eec733 contentGridItem relative h-full " > <div x-data='anchorMenu()' class="h-full" x-intersect.margin.-50%='setActiveLinkByID("9de6b80c-1e35-44a8-a3ca-4b5753eec733");'> <div class="contentGridItem__container relative h-full" dir="ltr"> <div class="background--9de6b80c-1e35-44a8-a3ca-4b5753eec733 py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-4 text-primary h-full animateImage bg-transparent relative z-10"> <div class="ContentGrid container mx-auto "> <div class="flex md:flex md:flex-row lg:flex-row flex-wrap justify-start items-center -mx-0 py-0 md:-mx-0 md:py-0 lg:-mx-0 lg:py-0"> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full lg:w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-4 lg:py-0 px-4 md:px-4 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><span class="text-body-6"><span class="text-title-6"><span class="text-white"><strong>For adults with moderate to severe rheumatoid arthritis (RA) who have not been helped enough by other RA medicines.</strong></span></span></span></p> <p><span class="text-body-6"><span class="text-title-6"><span class="text-white"><strong>For adults with polymyalgia rheumatica (PMR) after corticosteroids (steroids) have been used and did not work well or when a slow decrease in the dose of corticosteroids (taper) cannot be tolerated.</strong></span></span></span></p> </div> </div> </div> </div> </div> <div class=""></div> </div> </div> </div> </section> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-4 lg:px-4 items-stretch self-auto bg-transparent" x-data="" dir="ltr"> <section id="64b472e8-78aa-44e7-9068-450a6e513066" class="contentGridItem--64b472e8-78aa-44e7-9068-450a6e513066 contentGridItem relative h-full " > <div x-data='anchorMenu()' class="h-full" x-intersect.margin.-50%='setActiveLinkByID("64b472e8-78aa-44e7-9068-450a6e513066");'> <div class="contentGridItem__container relative h-full" dir="ltr"> <div 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</div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-4 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="flex items-center justify-center md:justify-center lg:justify-center "> <h2 class="contentBlock__title text-title-6 font-title text-primary1">Choose a condition</h2> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full md:w-9/12 lg:w-9/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-4 px-4 md:px-4 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div x-data="{id: 'HCP-PMR'}" class='w-full flex justify-center'> <button class="button button--default text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click.stop="$dispatch('open-modal',{id}); $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Polymyalgia rheumatica (PMR)`, 'context': 'other' }); " > Polymyalgia rheumatica (PMR) </button> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="mt-3"> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full md:w-9/12 lg:w-9/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-4 lg:py-0 px-4 md:px-4 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div x-data="{id: 'HCP-RA'}" class='w-full flex justify-center'> <button class="button button--default text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click.stop="$dispatch('open-modal',{id}); $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Rheumatoid arthritis (RA)`, 'context': 'other' }); " > Rheumatoid arthritis (RA) </button> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full lg:w-11/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-4 px-0 md:px-8 lg:px-8 self-auto contentBlock flex flex-col text-center md:text-center lg:text-center text- bg- bg-transparent" x-data="" dir="ltr"> <div class="flex items-center justify-center md:justify-center lg:justify-center "> <h2 class="contentBlock__title text-title-6 font-title text-primary1">This information is intended for US healthcare professionals only. 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" href="/pmr/" target="_self" > Polymyalgia rheumatica (PMR) </a> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="mt-3"> </div> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 lg:my-0 lg:px-0 w-full md:w-9/12 lg:w-9/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-4 lg:py-0 px-4 md:px-4 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div class='w-full flex justify-center'> <a class="button button--default text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click=" $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Rheumatoid arthritis (RA)`, 'context': 'other' }); " href="/ra/" target="_self" > Rheumatoid arthritis (RA) </a> </div> </div> </div> </div> </div> <div class=""></div> </div> </div> </div> </section> </div> </div> </div> </div> <div class=""></div> </div> </div> </div> </section> </div> </div> </div> </div> <div class=""></div> </div> </div> </div> </section> </div> </div> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-4 lg:py-4 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> </div> </div> </div> </div> <div class=""></div> </div> </div> </div> </section> </div> </div> </div> </div> <div class=""></div> </div> </div> </div> </section> <main role="main" id="main" class="relative flex-1" > <section id="c90be24d-9eb6-4371-b170-517e01c85871" class="contentGridItem--c90be24d-9eb6-4371-b170-517e01c85871 contentGridItem relative h-full " > <div x-data='anchorMenu()' class="h-full" x-intersect.margin.-50%='setActiveLinkByID("c90be24d-9eb6-4371-b170-517e01c85871");'> <div class="contentGridItem__container relative h-full" dir="ltr"> <div class="background--c90be24d-9eb6-4371-b170-517e01c85871 py-0 text-primary h-full animateImage bg-transparent relative z-10"> <div class="ContentGrid container mx-auto lg:pt-4 lg:pb-0 md:pt-4 md:pb-0 pt-4 pb-0"> </div> <div class=""></div> </div> </div> </div> </section> <script type="text/javascript"> /* eslint-disable */ document.addEventListener("alpine:init", () => { Alpine.data("isi", (config) => ({ ...config, scrollMod: null, uuid: config.uuid, contextPath: config.contextPath, isIsiCollapsed: false, isIsiExpanded: false, isIntersecting: false, isDesktop: this.getDesktopValue, get getDesktopValue() { this.isDesktop = this.$breakpointIs("lg"); 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KEVZARA can lower the ability of your immune system to fight infections. Some people have had serious infections while using KEVZARA, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections. Your healthcare provider should test you for TB before starting KEVZARA. Your healthcare provider should monitor you closely for signs and symptoms of TB during treatment with KEVZARA.</strong></span></li> <li>Before starting KEVZARA, tell your healthcare provider if you <ul> <li>think you have an infection or have signs or symptoms of an infection, with or without a fever such as sweats or chills, muscle aches, a cough, shortness of breath, blood in your phlegm, weight loss, warm, red, or painful skin or sores on your body, diarrhea or stomach pain, burning when you urinate or urinating more often than normal, if you feel very tired, or if you are being treated for an infection, get a lot of infections or have repeated infections.</li> <li>have diabetes, HIV, or a weakened immune system.</li> <li>have TB, or have been in close contact with someone with TB.</li> <li>live or have lived, or have traveled to certain parts of the country (such as the Ohio and Mississippi River valleys and the Southwest) where there is an increased chance of getting certain fungal infections (histoplasmosis, coccidioidomycosis, or blastomycosis).</li> <li>have or have had hepatitis.</li> </ul> </li> <li>After starting KEVZARA, call your healthcare provider right away if you have any symptoms of an infection.</li> <li><strong>CHANGES IN CERTAIN LABORATORY TEST RESULTS: </strong>Your healthcare provider should do blood tests before and after starting KEVZARA to check for low neutrophil (white blood cells that help the body fight off bacterial infections) counts, low platelet (blood cells that help with blood clotting and stop bleeding) counts, and an increase in certain liver function tests. Changes in test results are common with KEVZARA and can be severe. You may also have changes in other laboratory tests, such as your blood cholesterol levels. Your healthcare provider should do blood tests 4 to 8 weeks after starting KEVZARA and then every 6 months during treatment to check for an increase in blood cholesterol levels.</li> <li><strong>TEARS (PERFORATION) OF THE STOMACH OR INTESTINES:</strong> Tell your healthcare provider if you have had a condition known as diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines. Some people using KEVZARA get tears in their stomach or intestine. This happens most often in people who also take nonsteroidal anti-inflammatory drugs (NSAIDS), corticosteroids, or methotrexate. Call your healthcare provider right away if you have fever and stomach (abdominal) pain that does not go away.</li> <li><strong>CANCER: </strong>KEVZARA may increase your risk of certain cancers by changing the way your immune system works. Tell your healthcare provider if you have ever had any type of cancer.</li> <li><strong>SERIOUS ALLERGIC REACTIONS:</strong> Serious allergic reactions can happen with KEVZARA. Get medical attention right away if you have any of the following signs: shortness of breath or trouble breathing; feeling dizzy or faint; swelling of your lips, tongue, or face; moderate or severe stomach (abdominal) pain or vomiting; or chest pain.</li> <li>Do not use KEVZARA if you are allergic to sarilumab or any of the ingredients of KEVZARA.</li> <li>Before using KEVZARA, tell your healthcare provider if you <ul> <li>have an infection.</li> <li>have liver problems.</li> <li>have had stomach (abdominal) pain or a condition known as diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines.</li> <li>recently received or are scheduled to receive a vaccine. People who take KEVZARA should not receive live vaccines. <ul> <li>all vaccines should be brought up-to-date before starting KEVZARA, unless urgent treatment initiation is required.</li> </ul> </li> <li>plan to have surgery or a medical procedure.</li> <li>are pregnant or plan to become pregnant. It is not known if KEVZARA will harm your unborn baby.</li> <li>are breastfeeding or plan to breastfeed. Talk to your healthcare provider about the best way to feed your baby if you use KEVZARA. It is not known if KEVZARA passes into your breast milk.</li> <li>take prescription or nonprescription medicines, vitamins, or herbal supplements. It is especially important to tell your healthcare provider if you use: <ul> <li>any other medicines to treat your RA or PMR. Using KEVZARA with these medicines may increase your risk of infection.</li> <li>medicines that affect the way certain liver enzymes work. Ask your healthcare provider if you are not sure if your medicine is one of these.</li> </ul> </li> </ul> </li> <li>The most common side effects include: <ul> <li>injection site redness</li> <li>injection site itching</li> <li>upper respiratory tract infection</li> <li>urinary tract infection</li> <li>nasal congestion, sore throat, and runny nose</li> </ul> </li> </ul> <p><strong>These are not all the possible side effects of KEVZARA. Tell your doctor about any side effect that bothers you or does not go away. You are encouraged to report side effects of prescription drugs to the FDA at <a href="https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program" target="_blank"><u>www.fda.gov/medwatch</u></a> or call 1-800-FDA-1088.</strong></p> <p><em>To learn more, talk about KEVZARA with your healthcare provider or pharmacist. The FDA-approved Medication Guide and Prescribing Information can be found at <a href="https://www.kevzara.com/" target="_blank"><u>www.KEVZARA.com</u></a> or by calling <a href="tel:1-844-538-9272">1-844-KEVZARA</a><strong>.</strong></em></p> <p><span class="text-primary1"><strong>Please click here to see full <a href="https://products.sanofi.us/kevzara/Kevzara.pdf" target="_blank"><u>Prescribing Information</u></a>, including risk of SERIOUS SIDE EFFECTS, and <a href="https://products.sanofi.us/kevzara/kevzara_medguide.pdf" target="_blank"><u>Medication Guide</u></a>.</strong></span></p> </div> </div> </div> <div class="gridComponent mb-4 mt-3 flex flex-col w-full md:w-full lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-4 md:px-0 lg:px-8 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><strong><span class="text-primary1">What is KEVZARA?</span></strong></p> <p>KEVZARA is an injectable prescription medicine called an interleukin-6 (IL-6) receptor blocker. KEVZARA is used to treat adult patients with:</p> <ul> <li>moderately to severely active rheumatoid arthritis (RA) after at least one other medicine called a disease-modifying antirheumatic drug (DMARD) has been used and did not work well or could not be tolerated.</li> <li>polymyalgia rheumatica (PMR) after corticosteroids have been used and did not work well or when a slow decrease in the dose of corticosteroids (taper) cannot be tolerated.</li> </ul> </div> </div> </div> </div> </div> </div> </div> </div> <div style="height: 23.5%" :class="!isIntersecting || 'invisible opacity-0'" class="isi-tray z-50 transition-opacity fixed bottom-0 left-0 right-0 bg-white mb-0 border-t border-"> <div class="isiTray__contentSectionItem flex flex-col lg:flex-row py-0 md:py-0 lg:py-0 px-0 md:px-8 lg:px-8 w-full md:w-full lg:w-full container mx-auto"> <div class="flex"> <h3 class="mobile-title pt-1 text- text-lg font-title w-auto lg:w-full block lg:hidden"> </h3> <a href="#in-page-isi" aria-label="Read more" class="h-5 md:h-auto ml-auto font-title text-primary1 text-base md:text-lg flex items-start md:items-center justify-end relative md:absolute right-2 top-2 md:top-1 mr-0 md:mr-4 whitespace-nowrap md:whitespace-normal"> <span class="hidden sm:block">Read more</span> <svg class="w-5 h-6 ml-1.5 fill-current" aria-hidden="true" role="img"> <use xlink:href="/.resources/sanofi-lm-platform/themes/sanofi-platform/src/img/sprites/global.svg#chevron-circle-down"></use> </svg> </a> </div> <div class="ContentGrid "> <div class="flex md:flex lg:flex-row flex-wrap "> <div class="gridComponent mb-4 mt-3 flex flex-col w-full lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-4 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><strong><span class="text-primary1">IMPORTANT SAFETY INFORMATION</span></strong></p> <p><span class="text-black"><strong>KEVZARA</strong></span><strong>® (sarilumab)</strong><span class="text-black"><strong> can cause serious side effects including:</strong></span></p> <ul> <li><span class="text-black"><strong>SERIOUS INFECTIONS: KEVZARA is a medicine that affects your immune system. KEVZARA can lower the ability of your immune system to fight infections. Some people have had serious infections while using KEVZARA, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections. Your healthcare provider should test you for TB before starting KEVZARA. Your healthcare provider should monitor you closely for signs and symptoms of TB during treatment with KEVZARA.</strong></span></li> <li>Before starting KEVZARA, tell your healthcare provider if you <ul> <li>think you have an infection or have signs or symptoms of an infection, with or without a fever such as sweats or chills, muscle aches, a cough, shortness of breath, blood in your phlegm, weight loss, warm, red, or painful skin or sores on your body, diarrhea or stomach pain, burning when you urinate or urinating more often than normal, if you feel very tired, or if you are being treated for an infection, get a lot of infections or have repeated infections.</li> <li>have diabetes, HIV, or a weakened immune system.</li> <li>have TB, or have been in close contact with someone with TB.</li> <li>live or have lived, or have traveled to certain parts of the country (such as the Ohio and Mississippi River valleys and the Southwest) where there is an increased chance of getting certain fungal infections (histoplasmosis, coccidioidomycosis, or blastomycosis).</li> <li>have or have had hepatitis.</li> </ul> </li> <li>After starting KEVZARA, call your healthcare provider right away if you have any symptoms of an infection.</li> <li><strong>CHANGES IN CERTAIN LABORATORY TEST RESULTS: </strong>Your healthcare provider should do blood tests before and after starting KEVZARA to check for low neutrophil (white blood cells that help the body fight off bacterial infections) counts, low platelet (blood cells that help with blood clotting and stop bleeding) counts, and an increase in certain liver function tests. Changes in test results are common with KEVZARA and can be severe. You may also have changes in other laboratory tests, such as your blood cholesterol levels. Your healthcare provider should do blood tests 4 to 8 weeks after starting KEVZARA and then every 6 months during treatment to check for an increase in blood cholesterol levels.</li> <li><strong>TEARS (PERFORATION) OF THE STOMACH OR INTESTINES:</strong> Tell your healthcare provider if you have had a condition known as diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines. Some people using KEVZARA get tears in their stomach or intestine. This happens most often in people who also take nonsteroidal anti-inflammatory drugs (NSAIDS), corticosteroids, or methotrexate. Call your healthcare provider right away if you have fever and stomach (abdominal) pain that does not go away.</li> <li><strong>CANCER: </strong>KEVZARA may increase your risk of certain cancers by changing the way your immune system works. Tell your healthcare provider if you have ever had any type of cancer.</li> <li><strong>SERIOUS ALLERGIC REACTIONS:</strong> Serious allergic reactions can happen with KEVZARA. Get medical attention right away if you have any of the following signs: shortness of breath or trouble breathing; feeling dizzy or faint; swelling of your lips, tongue, or face; moderate or severe stomach (abdominal) pain or vomiting; or chest pain.</li> <li>Do not use KEVZARA if you are allergic to sarilumab or any of the ingredients of KEVZARA.</li> <li>Before using KEVZARA, tell your healthcare provider if you <ul> <li>have an infection.</li> <li>have liver problems.</li> <li>have had stomach (abdominal) pain or a condition known as diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines.</li> <li>recently received or are scheduled to receive a vaccine. People who take KEVZARA should not receive live vaccines. <ul> <li>all vaccines should be brought up-to-date before starting KEVZARA, unless urgent treatment initiation is required.</li> </ul> </li> <li>plan to have surgery or a medical procedure.</li> <li>are pregnant or plan to become pregnant. It is not known if KEVZARA will harm your unborn baby.</li> <li>are breastfeeding or plan to breastfeed. Talk to your healthcare provider about the best way to feed your baby if you use KEVZARA. It is not known if KEVZARA passes into your breast milk.</li> <li>take prescription or nonprescription medicines, vitamins, or herbal supplements. It is especially important to tell your healthcare provider if you use: <ul> <li>any other medicines to treat your RA or PMR. Using KEVZARA with these medicines may increase your risk of infection.</li> <li>medicines that affect the way certain liver enzymes work. Ask your healthcare provider if you are not sure if your medicine is one of these.</li> </ul> </li> </ul> </li> <li>The most common side effects include: <ul> <li>injection site redness</li> <li>injection site itching</li> <li>upper respiratory tract infection</li> <li>urinary tract infection</li> <li>nasal congestion, sore throat, and runny nose</li> </ul> </li> </ul> <p><strong>These are not all the possible side effects of KEVZARA. Tell your doctor about any side effect that bothers you or does not go away. You are encouraged to report side effects of prescription drugs to the FDA at <a href="https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program" target="_blank"><u>www.fda.gov/medwatch</u></a> or call 1-800-FDA-1088.</strong></p> <p><em>To learn more, talk about KEVZARA with your healthcare provider or pharmacist. The FDA-approved Medication Guide and Prescribing Information can be found at <a href="https://www.kevzara.com/" target="_blank"><u>www.KEVZARA.com</u></a> or by calling <a href="tel:1-844-538-9272">1-844-KEVZARA</a><strong>.</strong></em></p> <p><span class="text-primary1"><strong>Please click here to see full <a href="https://products.sanofi.us/kevzara/Kevzara.pdf" target="_blank"><u>Prescribing Information</u></a>, including risk of SERIOUS SIDE EFFECTS, and <a href="https://products.sanofi.us/kevzara/kevzara_medguide.pdf" target="_blank"><u>Medication Guide</u></a>.</strong></span></p> </div> </div> </div> <div class="gridComponent mb-4 mt-3 flex flex-col w-full md:w-full lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-4 md:px-0 lg:px-8 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><strong><span class="text-primary1">What is KEVZARA?</span></strong></p> <p>KEVZARA is an injectable prescription medicine called an interleukin-6 (IL-6) receptor blocker. KEVZARA is used to treat adult patients with:</p> <ul> <li>moderately to severely active rheumatoid arthritis (RA) after at least one other medicine called a disease-modifying antirheumatic drug (DMARD) has been used and did not work well or could not be tolerated.</li> <li>polymyalgia rheumatica (PMR) after corticosteroids have been used and did not work well or when a slow decrease in the dose of corticosteroids (taper) cannot be tolerated.</li> </ul> </div> </div> </div> </div> </div> </div> </div> </div> <section id="1019096c-4f3e-410e-b212-34c35aaf3ae0" class="contentGridItem--1019096c-4f3e-410e-b212-34c35aaf3ae0 contentGridItem relative h-full " > <div x-data='anchorMenu()' class="h-full" x-intersect.margin.-50%='setActiveLinkByID("1019096c-4f3e-410e-b212-34c35aaf3ae0");'> <div class="contentGridItem__container relative h-full" dir="ltr"> <div class="background--1019096c-4f3e-410e-b212-34c35aaf3ae0 py-0 text-primary h-full animateImage bg-transparent relative z-10"> <div class="ContentGrid container mx-auto lg:pt-0 lg:pb-8 md:pt-0 md:pb-8 pt-0 pb-8"> <div class="flex md:flex md:flex-row lg:flex-row flex-wrap justify-center items-center -mx-0 py-0 md:-mx-0 md:py-0 lg:-mx-0 lg:py-0"> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-11/12 md:w-11/12 lg:w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-8 lg:py-4 px-4 md:px-8 lg:px-8 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg-secondary3 secondary3" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><em>The health information contained herein is provided for general educational purposes only. 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class="background--73c60529-031d-4654-8ee2-a63f35b8b3ef py-0 md:py-0 lg:py-4 px-0 md:px-4 lg:px-4 text-primary h-full animateImage bg-transparent relative z-10"> <div class="ContentGrid container mx-auto "> <div class="flex md:flex md:flex-row lg:flex-row flex-wrap justify-center items-center -mx-0 py-0 md:-mx-0 md:py-0 lg:-mx-0 lg:py-0"> <div class="gridComponent flex flex-col my-0 px-0 md:my-0 md:px-0 lg:my-0 lg:px-0 w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-4 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><span class="text-white">© 2024 Sanofi and Regeneron Pharmaceuticals, Inc. 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return { open: opts.open, focus: opts.focus, focusTrap: opts.focusTrap, initState(state) { if (state) { this.open = state; } }, preventScroll() { document.body.style.overflow = "hidden"; }, restoreScroll() { document.body.style.overflow = "auto"; }, initFocus(id) { const container = document.getElementById("modal-" + id); let btn = container.querySelector(".close-modal-btn"); if (container) { const props = { fallbackFocus: container, allowOutsideClick: true, preventScroll: true, onActivate: () => { //set first button as the first focus when modal is opened. bug with this package requires this odd syntax :( setTimeout("document.getElementById('modal-" + id + "').querySelectorAll('button')[0].focus();", 50); }, } if (btn) { props.initialFocus = btn; } this.focusTrap = this.$createFocusTrap("#modal-" + id, props); this.$watch("open", (value) => { if (value === true) { this.focusTrap.activate(); } else { this.focusTrap.deactivate(); } }); } }, pauseVideo() { var videos = document.querySelectorAll("iframe, video"); 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if (local) { this.open = !local; } }, removeDisabledAttribute(id) { let inputElement = document.getElementById(id); inputElement.removeAttribute("disabled"); inputElement.checked = true; }, addDisabledAttribute(id) { let inputElement = document.getElementById(id); inputElement.setAttribute("disabled", "disabled"); inputElement.checked = false; }, appendToBody() { document.body.appendChild(this.$el); }, }; }); }); </script> <script type="text/json" class="leaveSitePrompt__data--aa0694df-1084-405d-83d8-b44c40194338"> { "filterType": "whitelist", "list": [ "https://products.sanofi.us/kevzara/kevzara_medguide.pdf", "https://products.sanofi.us/kevzara/Kevzara.pdf", "https://www.kevzara.com/" ] } </script> <div id="" class="absolute bottom-0 h-0" x-data="modal()" x-init="initFocus('HCP-PMR'); initState(false); validateStorage('', 'cookies'); " x-cloak> <div class="modal__parent top-0 left-0 right-0 bottom-0 z-50 flex items-center justify-center w-full h-full bg-black bg-opacity-70 backdrop-filter backdrop-none" :class="{'hidden': !open, 'fixed': open}" @open-modal.window="if ($event.detail.id == 'HCP-PMR') open = true, preventScroll()" @close-modal.window="open = false; restoreScroll()" @click.self="open = false, pauseVideo(), restoreScroll()" x-on:keydown.escape.window="open = false, pauseVideo(), restoreScroll()" > <div tabindex="-1" role="dialog" id="modal-HCP-PMR" data-id="HCP-PMR" data-gtmContext="other" aria-modal="true" class=" bg-white text-black relative overflow-auto h-auto max-h-90vh px-4 py-12 mx-2 text-left shadow-xl w-full md:w-2/3 lg:w-4/12 md:max-w-7xl md:py-8 md:px-8 lg:py-12 lg:px-12 md:mx-0"> <button @click="open = false, pauseVideo(), restoreScroll()" @focus="open = true" class="close-modal-btn flex absolute top-2 right-3" aria-label="close" type="button" > <span class="font-body text-default leading-none overflow-hidden text-3xl">脳</span> </button> <div class="ContentGrid "> <div class="flex md:flex lg:flex-row flex-wrap "> <div class="gridComponent flex flex-col w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><img alt="" src="/dam/jcr:a55db5ea-aad4-4764-8ef1-7a852cddbc74/logo-kevzara-200-mg-injection.2024-05-08-09-50-57.svg" style="margin-top: 10px; margin-bottom: 10px; height: 98px; width: 199px;" /></p> <p><a href="." style="font-family:'Gotham-Bold';pointer-events:none;"><span class="text-primary1"><strong><span class="text-title-3">This information is intended for US Healthcare Professionals only.</span></strong></span></a></p> </div> </div> </div> <div class="gridComponent flex flex-col w-full md:w-6/12 lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-0 lg:py-0 px-16 md:px-0 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div x-data="{id: ''}" class='w-full flex justify-start'> <a class="button button--secondary text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click="$dispatch('close-modal'); $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Cancel`, 'context': 'other' }); " > Cancel </a> </div> </div> </div> <div class="gridComponent flex flex-col w-full md:w-6/12 lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-16 md:px-4 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div class='w-full flex justify-center'> <a class="button button--tertiary text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click=" $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Continue`, 'context': 'other' }); " href="/hcp/pmr/" target="_self" > Continue </a> </div> </div> </div> </div> </div> </div> </div> </div> <script type="text/javascript" async> /* eslint-disable */ document.addEventListener("alpine:init", () => { Alpine.data("modal", (config) => { const opts = { focus: false, open: false, focusTrap: null, ...config, }; return { open: opts.open, focus: opts.focus, focusTrap: opts.focusTrap, initState(state) { if (state) { this.open = state; } }, preventScroll() { document.body.style.overflow = "hidden"; }, restoreScroll() { document.body.style.overflow = "auto"; }, initFocus(id) { const container = document.getElementById("modal-" + id); let btn = container.querySelector(".close-modal-btn"); if (container) { const props = { fallbackFocus: container, allowOutsideClick: true, preventScroll: true, onActivate: () => { //set first button as the first focus when modal is opened. bug with this package requires this odd syntax :( setTimeout("document.getElementById('modal-" + id + "').querySelectorAll('button')[0].focus();", 50); }, } if (btn) { props.initialFocus = btn; } this.focusTrap = this.$createFocusTrap("#modal-" + id, props); this.$watch("open", (value) => { if (value === true) { this.focusTrap.activate(); } else { this.focusTrap.deactivate(); } }); } }, pauseVideo() { var videos = document.querySelectorAll("iframe, video"); Array.prototype.forEach.call(videos, function (video) { if (video.tagName.toLowerCase() === "video") { video.pause(); } else { //pause iframe videos without loading/calling the Vimeo ifame api if (video.parentElement.classList.contains("vimeo-iframe")) { video.contentWindow.postMessage(JSON.stringify({ method: "pause" }), "*"); } else { //pause iframe videos without loading/calling the Youtube ifame api video.contentWindow.postMessage(JSON.stringify({ event: "command", func: "stopVideo" }), "*"); } } }); }, validateStorage(name, storageType="cookies") { switch(storageType) { case "session": this.validateSessionStorage(name); break; case "local": this.validateLocalStorage(name); break; default: this.validateCookie(name); } }, validateCookie(name) { const cookie = this.$getCookie(name); if (cookie) { this.open = !cookie; } }, validateSessionStorage(name) { const session = window.sessionStorage.getItem(name); if (session) { this.open = !session; } }, validateLocalStorage(name) { const local = window.localStorage.getItem(name); if (local) { this.open = !local; } }, removeDisabledAttribute(id) { let inputElement = document.getElementById(id); inputElement.removeAttribute("disabled"); inputElement.checked = true; }, addDisabledAttribute(id) { let inputElement = document.getElementById(id); inputElement.setAttribute("disabled", "disabled"); inputElement.checked = false; }, appendToBody() { document.body.appendChild(this.$el); }, }; }); }); </script> <div id="" class="absolute bottom-0 h-0" x-data="modal()" x-init="initFocus('HCP-RA'); initState(false); validateStorage('', 'cookies'); " x-cloak> <div class="modal__parent top-0 left-0 right-0 bottom-0 z-50 flex items-center justify-center w-full h-full bg-black bg-opacity-70 backdrop-filter backdrop-none" :class="{'hidden': !open, 'fixed': open}" @open-modal.window="if ($event.detail.id == 'HCP-RA') open = true, preventScroll()" @close-modal.window="open = false; restoreScroll()" @click.self="open = false, pauseVideo(), restoreScroll()" x-on:keydown.escape.window="open = false, pauseVideo(), restoreScroll()" > <div tabindex="-1" role="dialog" id="modal-HCP-RA" data-id="HCP-RA" data-gtmContext="other" aria-modal="true" class=" bg-white text-black relative overflow-auto h-auto max-h-90vh px-4 py-12 mx-2 text-left shadow-xl w-full md:w-2/3 lg:w-4/12 md:max-w-7xl md:py-8 md:px-8 lg:py-12 lg:px-12 md:mx-0"> <button @click="open = false, pauseVideo(), restoreScroll()" @focus="open = true" class="close-modal-btn flex absolute top-2 right-3" aria-label="close" type="button" > <span class="font-body text-default leading-none overflow-hidden text-3xl">脳</span> </button> <div class="ContentGrid "> <div class="flex md:flex lg:flex-row flex-wrap "> <div class="gridComponent flex flex-col w-full self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><img alt="" src="/dam/jcr:a55db5ea-aad4-4764-8ef1-7a852cddbc74/logo-kevzara-200-mg-injection.2024-05-08-09-50-57.svg" style="margin-top: 10px; margin-bottom: 10px; height: 98px; width: 199px;" /></p> <p><a href="." style="font-family:'Gotham-Bold';pointer-events:none;"><span class="text-primary1"><strong><span class="text-title-3">This information is intended for US Healthcare Professionals only.</span></strong></span></a></p> </div> </div> </div> <div class="gridComponent flex flex-col w-full md:w-6/12 lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-4 md:py-0 lg:py-0 px-16 md:px-0 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div x-data="{id: ''}" class='w-full flex justify-start'> <a class="button button--secondary text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click="$dispatch('close-modal'); $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Cancel`, 'context': 'other' }); " > Cancel </a> </div> </div> </div> <div class="gridComponent flex flex-col w-full md:w-6/12 lg:w-6/12 self-auto " > <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-16 md:px-4 lg:px-4 self-auto bg-transparent" x-data="" dir="ltr"> <div class='w-full flex justify-center'> <a class="button button--tertiary text-center font-title overflow-hidden inline-block border text-size-default border rounded-full border-solid w-full text-center " @click=" $dispatch('track-event', { 'event': 'cmp_event', 'event_type': 'cta', 'title': `Continue`, 'context': 'other' }); " href="/hcp/ra/" target="_self" > Continue </a> </div> </div> </div> </div> </div> </div> </div> </div> <script type="text/javascript" async> /* eslint-disable */ document.addEventListener("alpine:init", () => { Alpine.data("modal", (config) => { const opts = { focus: false, open: false, focusTrap: null, ...config, }; return { open: opts.open, focus: opts.focus, focusTrap: opts.focusTrap, initState(state) { if (state) { this.open = state; } }, preventScroll() { document.body.style.overflow = "hidden"; }, restoreScroll() { document.body.style.overflow = "auto"; }, initFocus(id) { const container = document.getElementById("modal-" + id); let btn = container.querySelector(".close-modal-btn"); if (container) { const props = { fallbackFocus: container, allowOutsideClick: true, preventScroll: true, onActivate: () => { //set first button as the first focus when modal is opened. bug with this package requires this odd syntax :( setTimeout("document.getElementById('modal-" + id + "').querySelectorAll('button')[0].focus();", 50); }, } if (btn) { props.initialFocus = btn; } this.focusTrap = this.$createFocusTrap("#modal-" + id, props); this.$watch("open", (value) => { if (value === true) { this.focusTrap.activate(); } else { this.focusTrap.deactivate(); } }); } }, pauseVideo() { var videos = document.querySelectorAll("iframe, video"); Array.prototype.forEach.call(videos, function (video) { if (video.tagName.toLowerCase() === "video") { video.pause(); } else { //pause iframe videos without loading/calling the Vimeo ifame api if (video.parentElement.classList.contains("vimeo-iframe")) { video.contentWindow.postMessage(JSON.stringify({ method: "pause" }), "*"); } else { //pause iframe videos without loading/calling the Youtube ifame api video.contentWindow.postMessage(JSON.stringify({ event: "command", func: "stopVideo" }), "*"); } } }); }, validateStorage(name, storageType="cookies") { switch(storageType) { case "session": this.validateSessionStorage(name); break; case "local": this.validateLocalStorage(name); break; default: this.validateCookie(name); } }, validateCookie(name) { const cookie = this.$getCookie(name); if (cookie) { this.open = !cookie; } }, validateSessionStorage(name) { const session = window.sessionStorage.getItem(name); if (session) { this.open = !session; } }, validateLocalStorage(name) { const local = window.localStorage.getItem(name); if (local) { this.open = !local; } }, removeDisabledAttribute(id) { let inputElement = document.getElementById(id); inputElement.removeAttribute("disabled"); inputElement.checked = true; }, addDisabledAttribute(id) { let inputElement = document.getElementById(id); inputElement.setAttribute("disabled", "disabled"); inputElement.checked = false; }, appendToBody() { document.body.appendChild(this.$el); }, }; }); }); </script> <script src="/.resources/sanofi-lm-platform/themes/sanofi-platform/dist/common~2024-11-22-23-24-03-000~cache.js" async></script> <script src="/.resources/sanofi-lm-platform/themes/sanofi-platform/dist/pages/DefaultPage~2024-11-22-23-24-03-000~cache.js" async></script> <script> (function () { const urlParams = new URLSearchParams(window.location.search); const userway = urlParams.get('accessibility'); if (userway) { const userwayScript = document.createElement('script'); userwayScript.src = "https://cdn.userway.org/widget.js"; // add the userway URL, instead of mimecast userwayScript.setAttribute("data-account", "ShD61QrwhP"); document.body.appendChild(userwayScript); } } )(); </script>  <style> footer #ot-sdk-btn.ot-sdk-show-settings, footer #ot-sdk-btn.optanon-show-settings { border: none; color: #ffffff; padding:0; word-wrap: normal; font-family: 'Gotham-Book', sans-serif !important; font-size: 16px; font-weight: 700; margin-left: -5px; text-decoration: underline; } footer #ot-sdk-btn.ot-sdk-show-settings:hover, footer #ot-sdk-btn.optanon-show-settings:hover { background:none; color: #ffffff; } @media (max-width:900px){ footer #ot-sdk-btn.ot-sdk-show-settings, footer #ot-sdk-btn.optanon-show-settings { border: none; color: #ffffff; padding:0; word-wrap: normal; font-family: 'Gotham-Book', sans-serif !important; font-size: 16px; margin-left: 12px; text-decoration: underline; font-weight: 700; } } </style> <script> const OTlinkFooterBtn =`<div class="gridComponent flex flex-col my-1 px-1 md:my-1 md:px-1 lg:my-1 lg:px-1 w-auto md:w-auto lg:w-auto self-auto "> <div style="" class="ContentSectionItem h-full w-full py-0 md:py-0 lg:py-0 px-0 md:px-0 lg:px-0 self-auto contentBlock flex flex-col text-left md:text-left lg:text-left text- bg- bg-transparent" x-data="" dir="ltr"> <div class="rich-text mt-3 text-base font-body"> <p><span class="text-body-5"><span class="text-primary1"><button id="ot-sdk-btn" class="ot-sdk-show-settings">Cookie Settings</button></span></span></p> </div> </div> </div>`; const OTcontainerAppend = document.querySelector('footer a[href="https://www.sanofi.com/en/accessibility-partial-compliance"]').closest('.gridComponent'); OTcontainerAppend.insertAdjacentHTML('afterend',OTlinkFooterBtn); const OTshowSettings = document.querySelector('.ot-sdk-show-settings'); OTshowSettings.onclick = function() { const OTCloseBtn = document.querySelector('.ot-close-icon'); OTCloseBtn.onclick = function() { const OTdarkBG = document.querySelector('.onetrust-pc-dark-filter'); OTdarkBG.style.display = 'none'; } } </script>   <script> const isiTray = document.querySelector('.isi-tray'); document.onscroll = function(e) { const elTop = document.querySelector('footer').getBoundingClientRect().top; if (elTop <= window.innerHeight) isiTray.classList.add('hidden'); else isiTray.classList.remove('hidden'); } </script>  <style> @media screen and (max-width:520px) { html,body{ overflow-x: hidden; } .isi-tray { width: 100vw; max-width: 100vw; box-sizing: border-box; } } </style> <script>  const OTfadeIn = document.querySelector('.ot-fade-in'); OTfadeIn.onclick = function(){ const OTcontainer = document.querySelector('#onetrust-consent-sdk'); OTcontainer.style.display = 'none'; } const OTbutton = document.querySelector('#ot-sdk-btn'); OTbutton.onclick = function(){ const OTcontainer = document.querySelector('#onetrust-banner-sdk'); OTcontainer.style.display = 'block'; }  </script> </body> </html>

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