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脯氨酸 - 维基百科,自由的百科全书
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未登录编辑者的页面 <a href="/wiki/Help:%E6%96%B0%E6%89%8B%E5%85%A5%E9%97%A8" aria-label="了解有关编辑的更多信息"><span>了解详情</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%B4%A1%E7%8C%AE" title="来自此IP地址的编辑列表[y]" accesskey="y"><span>贡献</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%AE%A8%E8%AE%BA%E9%A1%B5" title="对于来自此IP地址编辑的讨论[n]" accesskey="n"><span>讨论</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"><!-- CentralNotice --></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="站点"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目录" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目录</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">隐藏</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">序言</div> </a> </li> <li id="toc-生物化學" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#生物化學"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>生物化學</span> </div> </a> <ul id="toc-生物化學-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-蛋白質結構的特性" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#蛋白質結構的特性"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>蛋白質結構的特性</span> </div> </a> <ul id="toc-蛋白質結構的特性-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-順反異構物" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#順反異構物"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>順反異構物</span> </div> </a> <ul id="toc-順反異構物-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-用途" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#用途"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>用途</span> </div> </a> <ul id="toc-用途-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-特色" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#特色"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>特色</span> </div> </a> <ul id="toc-特色-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-歷史" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#歷史"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>歷史</span> </div> </a> <ul id="toc-歷史-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-合成" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#合成"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>合成</span> </div> </a> <ul id="toc-合成-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-参考文献" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#参考文献"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>参考文献</span> </div> </a> <ul id="toc-参考文献-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-延伸阅读" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#延伸阅读"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>延伸阅读</span> </div> </a> <ul id="toc-延伸阅读-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-参看" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#参看"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>参看</span> </div> </a> <ul id="toc-参看-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部链接" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部链接"> <div class="vector-toc-text"> <span class="vector-toc-numb">11</span> <span>外部链接</span> </div> </a> <ul id="toc-外部链接-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">脯氨酸</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。58种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-58" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">58种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A8%D8%B1%D9%88%D9%84%D9%8A%D9%86" title="برولين – 阿拉伯语" lang="ar" hreflang="ar" data-title="برولين" data-language-autonym="العربية" data-language-local-name="阿拉伯语" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Prolin" title="Prolin – 阿塞拜疆语" lang="az" hreflang="az" data-title="Prolin" data-language-autonym="Azərbaycanca" data-language-local-name="阿塞拜疆语" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%BE%D8%B1%D9%88%D9%84%DB%8C%D9%86" title="پرولین – South Azerbaijani" lang="azb" hreflang="azb" data-title="پرولین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%BB%D0%B8%D0%BD" title="Пролин – 保加利亚语" lang="bg" hreflang="bg" data-title="Пролин" data-language-autonym="Български" data-language-local-name="保加利亚语" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%AA%E0%A7%8D%E0%A6%B0%E0%A7%8B%E0%A6%B2%E0%A6%BF%E0%A6%A8" title="প্রোলিন – 孟加拉语" lang="bn" hreflang="bn" data-title="প্রোলিন" data-language-autonym="বাংলা" data-language-local-name="孟加拉语" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Prolin" title="Prolin – 波斯尼亚语" lang="bs" hreflang="bs" data-title="Prolin" data-language-autonym="Bosanski" data-language-local-name="波斯尼亚语" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Prolina" title="Prolina – 加泰罗尼亚语" lang="ca" hreflang="ca" data-title="Prolina" data-language-autonym="Català" data-language-local-name="加泰罗尼亚语" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Prolin" title="Prolin – 捷克语" lang="cs" hreflang="cs" data-title="Prolin" data-language-autonym="Čeština" data-language-local-name="捷克语" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Prolin" title="Prolin – 丹麦语" lang="da" hreflang="da" data-title="Prolin" data-language-autonym="Dansk" data-language-local-name="丹麦语" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Prolin" title="Prolin – 德语" lang="de" hreflang="de" data-title="Prolin" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A0%CF%81%CE%BF%CE%BB%CE%AF%CE%BD%CE%B7" title="Προλίνη – 希腊语" lang="el" hreflang="el" data-title="Προλίνη" data-language-autonym="Ελληνικά" data-language-local-name="希腊语" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Proline" title="Proline – 英语" lang="en" hreflang="en" data-title="Proline" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Prolino" title="Prolino – 世界语" lang="eo" hreflang="eo" data-title="Prolino" data-language-autonym="Esperanto" data-language-local-name="世界语" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Prolina" title="Prolina – 西班牙语" lang="es" hreflang="es" data-title="Prolina" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et badge-Q17437798 badge-goodarticle mw-list-item" title="优良条目"><a href="https://et.wikipedia.org/wiki/Proliin" title="Proliin – 爱沙尼亚语" lang="et" hreflang="et" data-title="Proliin" data-language-autonym="Eesti" data-language-local-name="爱沙尼亚语" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Prolina" title="Prolina – 巴斯克语" lang="eu" hreflang="eu" data-title="Prolina" data-language-autonym="Euskara" data-language-local-name="巴斯克语" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%D8%B1%D9%88%D9%84%DB%8C%D9%86" title="پرولین – 波斯语" lang="fa" hreflang="fa" data-title="پرولین" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Proliini" title="Proliini – 芬兰语" lang="fi" hreflang="fi" data-title="Proliini" data-language-autonym="Suomi" data-language-local-name="芬兰语" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Proline" title="Proline – 法语" lang="fr" hreflang="fr" data-title="Proline" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Prolina" title="Prolina – 加利西亚语" lang="gl" hreflang="gl" data-title="Prolina" data-language-autonym="Galego" data-language-local-name="加利西亚语" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A4%D7%A8%D7%95%D7%9C%D7%99%D7%9F" title="פרולין – 希伯来语" lang="he" hreflang="he" data-title="פרולין" data-language-autonym="עברית" data-language-local-name="希伯来语" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%AA%E0%A5%8D%E0%A4%B0%E0%A5%8B%E0%A4%B2%E0%A4%BF%E0%A4%A8" title="प्रोलिन – 印地语" lang="hi" hreflang="hi" data-title="प्रोलिन" data-language-autonym="हिन्दी" data-language-local-name="印地语" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Prolin" title="Prolin – 克罗地亚语" lang="hr" hreflang="hr" data-title="Prolin" data-language-autonym="Hrvatski" data-language-local-name="克罗地亚语" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Prolin" title="Prolin – 匈牙利语" lang="hu" hreflang="hu" data-title="Prolin" data-language-autonym="Magyar" data-language-local-name="匈牙利语" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%8A%D6%80%D5%B8%D5%AC%D5%AB%D5%B6" title="Պրոլին – 亚美尼亚语" lang="hy" hreflang="hy" data-title="Պրոլին" data-language-autonym="Հայերեն" data-language-local-name="亚美尼亚语" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Prolina" title="Prolina – 印度尼西亚语" lang="id" hreflang="id" data-title="Prolina" data-language-autonym="Bahasa Indonesia" data-language-local-name="印度尼西亚语" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Prolina" title="Prolina – 意大利语" lang="it" hreflang="it" data-title="Prolina" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="プロリン – 日语" lang="ja" hreflang="ja" data-title="プロリン" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%BB%D0%B8%D0%BD" title="Пролин – 哈萨克语" lang="kk" hreflang="kk" data-title="Пролин" data-language-autonym="Қазақша" data-language-local-name="哈萨克语" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%94%84%EB%A1%A4%EB%A6%B0" title="프롤린 – 韩语" lang="ko" hreflang="ko" data-title="프롤린" data-language-autonym="한국어" data-language-local-name="韩语" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Prol%C3%AEn" title="Prolîn – 库尔德语" lang="ku" hreflang="ku" data-title="Prolîn" data-language-autonym="Kurdî" data-language-local-name="库尔德语" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-lb mw-list-item"><a href="https://lb.wikipedia.org/wiki/Prolin" title="Prolin – 卢森堡语" lang="lb" hreflang="lb" data-title="Prolin" data-language-autonym="Lëtzebuergesch" data-language-local-name="卢森堡语" class="interlanguage-link-target"><span>Lëtzebuergesch</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Prolinas" title="Prolinas – 立陶宛语" lang="lt" hreflang="lt" data-title="Prolinas" data-language-autonym="Lietuvių" data-language-local-name="立陶宛语" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Prol%C4%ABns" title="Prolīns – 拉脱维亚语" lang="lv" hreflang="lv" data-title="Prolīns" data-language-autonym="Latviešu" data-language-local-name="拉脱维亚语" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%BB%D0%B8%D0%BD" title="Пролин – 马其顿语" lang="mk" hreflang="mk" data-title="Пролин" data-language-autonym="Македонски" data-language-local-name="马其顿语" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Prolina" title="Prolina – 马来语" lang="ms" hreflang="ms" data-title="Prolina" data-language-autonym="Bahasa Melayu" data-language-local-name="马来语" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Proline" title="Proline – 荷兰语" lang="nl" hreflang="nl" data-title="Proline" data-language-autonym="Nederlands" data-language-local-name="荷兰语" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Prolin" title="Prolin – 挪威尼诺斯克语" lang="nn" hreflang="nn" data-title="Prolin" data-language-autonym="Norsk nynorsk" data-language-local-name="挪威尼诺斯克语" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Prolin" title="Prolin – 书面挪威语" lang="nb" hreflang="nb" data-title="Prolin" data-language-autonym="Norsk bokmål" data-language-local-name="书面挪威语" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Prolina" title="Prolina – 奥克语" lang="oc" hreflang="oc" data-title="Prolina" data-language-autonym="Occitan" data-language-local-name="奥克语" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Prolina" title="Prolina – 波兰语" lang="pl" hreflang="pl" data-title="Prolina" data-language-autonym="Polski" data-language-local-name="波兰语" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Prolina" title="Prolina – 葡萄牙语" lang="pt" hreflang="pt" data-title="Prolina" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Prolin%C4%83" title="Prolină – 罗马尼亚语" lang="ro" hreflang="ro" data-title="Prolină" data-language-autonym="Română" data-language-local-name="罗马尼亚语" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%BB%D0%B8%D0%BD" title="Пролин – 俄语" lang="ru" hreflang="ru" data-title="Пролин" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Prolin" title="Prolin – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Prolin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Prol%C3%ADn" title="Prolín – 斯洛伐克语" lang="sk" hreflang="sk" data-title="Prolín" data-language-autonym="Slovenčina" data-language-local-name="斯洛伐克语" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Prolin" title="Prolin – 斯洛文尼亚语" lang="sl" hreflang="sl" data-title="Prolin" data-language-autonym="Slovenščina" data-language-local-name="斯洛文尼亚语" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%BB%D0%B8%D0%BD" title="Пролин – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Пролин" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-su mw-list-item"><a href="https://su.wikipedia.org/wiki/Prolin" title="Prolin – 巽他语" lang="su" hreflang="su" data-title="Prolin" data-language-autonym="Sunda" data-language-local-name="巽他语" class="interlanguage-link-target"><span>Sunda</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Prolin" title="Prolin – 瑞典语" lang="sv" hreflang="sv" data-title="Prolin" data-language-autonym="Svenska" data-language-local-name="瑞典语" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%AA%E0%AF%81%E0%AE%B0%E0%AF%8B%E0%AE%B2%E0%AE%BF%E0%AE%A9%E0%AF%8D" title="புரோலின் – 泰米尔语" lang="ta" hreflang="ta" data-title="புரோலின்" data-language-autonym="தமிழ்" data-language-local-name="泰米尔语" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Prolin" title="Prolin – 土耳其语" lang="tr" hreflang="tr" data-title="Prolin" data-language-autonym="Türkçe" data-language-local-name="土耳其语" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%BB%D1%96%D0%BD" title="Пролін – 乌克兰语" lang="uk" hreflang="uk" data-title="Пролін" data-language-autonym="Українська" data-language-local-name="乌克兰语" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Prolin" title="Prolin – 乌兹别克语" lang="uz" hreflang="uz" data-title="Prolin" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="乌兹别克语" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Prolin" title="Prolin – 越南语" lang="vi" hreflang="vi" data-title="Prolin" data-language-autonym="Tiếng Việt" data-language-local-name="越南语" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E8%84%AF%E6%B0%A8%E9%85%B8" title="脯氨酸 – 吴语" lang="wuu" hreflang="wuu" data-title="脯氨酸" data-language-autonym="吴语" data-language-local-name="吴语" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-zh-min-nan mw-list-item"><a href="https://zh-min-nan.wikipedia.org/wiki/Prolin" title="Prolin – 闽南语" lang="nan" hreflang="nan" data-title="Prolin" data-language-autonym="閩南語 / Bân-lâm-gú" data-language-local-name="闽南语" class="interlanguage-link-target"><span>閩南語 / Bân-lâm-gú</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E8%84%AF%E6%B0%A8%E9%85%B8" title="脯氨酸 – 粤语" lang="yue" hreflang="yue" data-title="脯氨酸" data-language-autonym="粵語" data-language-local-name="粤语" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div class="after-portlet 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id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="zh" dir="ltr"><div id="noteTA-bc8628f1" class="noteTA"><div class="noteTA-local"><div data-noteta-code="zh-hans:氨基酸; zh-hant:胺基酸;"></div><div data-noteta-code="zh-hans:氨酸; zh-hant:胺酸;"></div></div></div> <style data-mw-deduplicate="TemplateStyles:r84001320">.mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}</style> <table class="infobox ib-chembox nounderlines" cellspacing="0" cellpadding="3" rules="all" style="background-color:#f0f0f0; float:right; margin: 0 0 1em 1em; border-color: #aaaaaa; border-style:solid; border:1px; border-collapse:collapse; empty-cells:show; width:305px; font-size:90%;"> <tbody><tr> <th colspan="2" style="font-size:120%; text-align:center; background:#d6e0dc;">脯氨酸 </th></tr> <tr> <td colspan="2" style="background:#ffffff; text-align:center;"> <table class="borderless"> <tbody><tr> <td><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/File:Prolin_-_Proline.svg" class="mw-file-description" title="Structural formula of proline"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Prolin_-_Proline.svg/100px-Prolin_-_Proline.svg.png" decoding="async" width="100" height="77" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Prolin_-_Proline.svg/150px-Prolin_-_Proline.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Prolin_-_Proline.svg/200px-Prolin_-_Proline.svg.png 2x" data-file-width="156" data-file-height="120" /></a><figcaption>Structural formula of proline</figcaption></figure> </td> <td><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/File:L-proline-3D-balls.png" class="mw-file-description" title="Ball and stick model of (S)-proline"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7c/L-proline-3D-balls.png/100px-L-proline-3D-balls.png" decoding="async" width="100" height="73" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7c/L-proline-3D-balls.png/150px-L-proline-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7c/L-proline-3D-balls.png/200px-L-proline-3D-balls.png 2x" data-file-width="1100" data-file-height="802" /></a><figcaption>Ball and stick model of (S)-proline</figcaption></figure> </td></tr></tbody></table> </td></tr> <tr> <td colspan="2" style="max-width:305px; word-wrap: break-word; text-align: center;"><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC名</a><br />Proline </td></tr> <tr> <td colspan="2" style="text-align: center;"><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">系统名</a><br />Pyrrolidine-2-carboxylic acid<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <th style="background:#D6E0DC; text-align:center;" colspan="2">识别 </th></tr> <tr> <td><a href="/wiki/CAS%E5%8F%B7" title="CAS号">CAS号</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=609-36-9">609-36-9</a></span> <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup><br /><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=344-25-2">344-25-2</a></span>(<i>R</i>) <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup><br /><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=147-85-3">147-85-3</a></span>(<i>S</i>) <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup> </td></tr> <tr> <td><a href="/wiki/PubChem" title="PubChem">PubChem</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/614">614</a></span><br /><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/8988">8988</a></span>(<i>R</i>)<br /><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/145742">145742</a></span>(<i>S</i>) </td></tr> <tr> <td><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.chemspider.com/594">594</a></span>, <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.chemspider.com/8640">8640</a></span> (<i>R</i>), <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.chemspider.com/128566">128566</a></span> (<i>S</i>) </td></tr> <tr> <td><a href="/wiki/SMILES" class="mw-redirect" title="SMILES">SMILES</a> </td> <td><div style="word-break:break-all;"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div> </div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0;"><li style="line-height: inherit; margin: 0"><span lang="en">OC(=O)C1CCCN1</span></li></ul> </div></div> </td></tr> <tr> <td><a href="/wiki/%E5%9B%BD%E9%99%85%E5%8C%96%E5%90%88%E7%89%A9%E6%A0%87%E8%AF%86" title="国际化合物标识">InChI</a> </td> <td><div style="word-break:break-all;"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div> </div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0;"><li style="line-height: inherit; margin: 0">1/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)</li></ul> </div></div> </td></tr> <tr> <td><a href="/wiki/%E4%BC%AF%E6%81%A9%E6%96%AF%E5%9D%A6%E6%95%B0%E6%8D%AE%E5%BA%93" class="mw-redirect" title="伯恩斯坦数据库">Beilstein</a> </td> <td>80812 </td></tr> <tr> <td><a href="/wiki/%E7%9B%96%E5%A2%A8%E6%9E%97%E6%95%B0%E6%8D%AE%E5%BA%93" title="盖墨林数据库">Gmelin</a> </td> <td>26927 </td></tr> <tr> <td><a href="/wiki/%E6%AC%A7%E7%9B%9F%E7%BC%96%E5%8F%B7" class="mw-redirect" title="欧盟编号">EINECS</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://ecb.jrc.ec.europa.eu/esis/index.php?GENRE=ECNO&ENTREE=210-189-3">210-189-3</a></span> </td></tr> <tr> <td><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:26271">26271</a></span> </td></tr> <tr> <td><a href="/wiki/%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E6%AF%92%E6%80%A7%E6%95%B0%E6%8D%AE%E5%BA%93" title="化学物质毒性数据库">RTECS</a> </td> <td>TW3584000 </td></tr> <tr> <td><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.drugbank.ca/cgi-bin/show_drug.cgi?CARD=DB02853">DB02853</a></span> </td></tr> <tr> <td><a href="/wiki/KEGG" title="KEGG">KEGG</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.genome.ad.jp/dbget-bin/www_bget?cpd:C16435">C16435</a></span> </td></tr> <tr> <td><a href="/wiki/%E5%8C%BB%E5%AD%A6%E4%B8%BB%E9%A2%98%E8%AF%8D" title="医学主题词">MeSH</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="//www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?mode=&view=expanded&term=Proline">Proline</a></span> </td></tr> <tr> <th style="background:#D6E0DC; text-align:center;" colspan="2">性质 </th></tr> <tr> <td><a href="/wiki/%E5%8C%96%E5%AD%A6%E5%BC%8F" title="化学式">化学式</a> </td> <td>C<sub>5</sub>H<sub>9</sub>NO<sub>2</sub> </td></tr> <tr> <td><a href="/wiki/%E6%91%A9%E5%B0%94%E8%B4%A8%E9%87%8F" title="摩尔质量">摩尔质量</a> </td> <td>115.13 g·mol<sup>−1</sup> </td></tr> <tr> <td>外观 </td> <td>透明晶体 </td></tr> <tr> <td><a href="/wiki/%E7%86%94%E7%82%B9" title="熔点">熔点</a> </td> <td>205-228 °C(478-501 K)(分解) </td></tr> <tr> <td><a href="/wiki/%E6%BA%B6%E8%A7%A3%E6%80%A7" class="mw-redirect" title="溶解性">溶解性</a> </td> <td>1.5g/100g(乙醇,19 °C)<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td><a href="/wiki/%E5%88%86%E9%85%8D%E7%B3%BB%E6%95%B0" title="分配系数">log P</a> </td> <td>-0.06 </td></tr> <tr> <td><a href="/wiki/%E9%85%B8%E5%BA%A6%E7%B3%BB%E6%95%B0" title="酸度系数">p<i>K</i><sub>a</sub></a> </td> <td><span lang="en">1.99(羧基)、10.96(氨基)<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span> </td></tr> <tr> <th style="background:#D6E0DC; text-align:center;" colspan="2">危险性 </th></tr> <tr> <td><a href="/wiki/%E5%AE%89%E5%85%A8%E5%BB%BA%E8%AD%B0%E6%A8%99%E6%BA%96%E8%A9%9E%E5%88%97%E8%A1%A8" title="安全建議標準詞列表">安全术语</a> </td> <td>S:<a href="/wiki/%E5%AE%89%E5%85%A8%E5%BB%BA%E8%AD%B0%E6%A8%99%E6%BA%96%E8%A9%9E%E5%88%97%E8%A1%A8#S22" title="安全建議標準詞列表"><abbr class="abbr" title="S22: 不要吸入微尘">S22</abbr></a>, <a href="/wiki/%E5%AE%89%E5%85%A8%E5%BB%BA%E8%AD%B0%E6%A8%99%E6%BA%96%E8%A9%9E%E5%88%97%E8%A1%A8#S24/25" title="安全建議標準詞列表"><abbr class="abbr" title="S24/25: 防止接触皮肤与眼睛">S24/25</abbr></a> </td></tr> <tr> <td style="background:#D6E0DC; text-align:center;" colspan="2">若非注明,所有数据均出自<a href="/wiki/%E6%A0%87%E5%87%86%E7%8A%B6%E6%80%81" title="标准状态">标准状态(25 ℃,100 kPa)</a>下。 </td></tr></tbody></table> <p><b>脯氨酸</b>(<span lang="en">Proline</span>,縮寫為<b>Pro </b>或<b>P </b>)是一個α-<a href="/wiki/%E6%B0%A8%E5%9F%BA%E9%85%B8" title="氨基酸">氨基酸</a>,又是一個環狀胺基酸,20個<a href="/wiki/DNA" class="mw-redirect" title="DNA">DNA</a>編碼的其中之一。它极易溶于水,微溶于乙醇、丙酮、苯,不溶于乙醚、丙醇。 虽然属于<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%83%BA%E5%9F%BA%E9%85%B8" title="蛋白胺基酸">蛋白胺基酸</a>,并不是<a href="/wiki/%E4%BC%AF%E8%83%BA" class="mw-redirect" title="伯胺">伯胺</a>而是<a href="/wiki/%E4%BB%B2%E8%83%BA" class="mw-redirect" title="仲胺">仲胺</a>(旧称为<a href="/wiki/%E4%BA%9E%E8%83%BA%E9%85%B8" title="亞胺酸">亞胺酸</a>),因此具有特殊構象剛性,影響肽的<a href="/wiki/%E4%BA%8C%E7%B4%9A%E7%B5%90%E6%A7%8B" title="二級結構">二級結構</a>。其對應<a href="/wiki/%E5%AF%86%E7%A0%81%E5%AD%90" class="mw-redirect" title="密码子">密碼子</a>為CCU、CCC、CCA和CCG。 </p><p>脯氨酸不是一種<a href="/wiki/%E5%BF%85%E9%9C%80%E6%B0%A8%E5%9F%BA%E9%85%B8" title="必需氨基酸">必需氨基酸</a>,人體可以自行合成。在20個蛋白質形成氨基酸中,其最特別之處在於胺氮被綁定到並非一個而是兩個烷基基團,因此使它具有<a href="/wiki/%E4%BB%B2%E8%83%BA" class="mw-redirect" title="仲胺">仲胺</a>结构,天然的脯氨酸为<small>L</small>型,手性碳的构型为<i>S</i>。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="生物化學"><span id=".E7.94.9F.E7.89.A9.E5.8C.96.E5.AD.B8"></span>生物化學</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=1" title="编辑章节:生物化學"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>脯氨酸由氨基酸的<small>L</small>-<a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8" title="谷氨酸">谷氨酸</a>和其中間前驅物<a href="/wiki/%E4%BA%9A%E6%B0%A8%E5%9F%BA%E4%B9%99%E9%85%B8" class="mw-redirect" title="亚氨基乙酸">亞氨基乙酸</a>(<a href="/w/index.php?title=(%27%27S%27%27)-1_-%E5%90%A1%E5%92%AF%E5%95%89-5-%E7%BE%A7%E9%85%B8%E7%94%B2%E9%85%AF&action=edit&redlink=1" class="new" title="(''S'')-1 -吡咯啉-5-羧酸甲酯(页面不存在)">(''S'')-1 -吡咯啉-5-羧酸甲酯</a>(P5C)<a href="/wiki/%E7%94%9F%E7%89%A9%E5%90%88%E6%88%90" title="生物合成">生物合成</a>而成,典型生物合成所需要的酶包括:<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <ol><li><a href="/w/index.php?title=%E8%B0%B7%E6%B0%A8%E9%85%B85-%E6%BF%80%E9%85%B6&action=edit&redlink=1" class="new" title="谷氨酸5-激酶(页面不存在)">谷氨酸5-激酶</a>,<a href="/w/index.php?title=%E8%B0%B7%E6%B0%A8%E9%85%B81-%E6%BF%80%E9%85%B6&action=edit&redlink=1" class="new" title="谷氨酸1-激酶(页面不存在)">谷氨酸1-激酶</a>(ATP依賴性)</li> <li><a href="/w/index.php?title=%E6%B0%A8%E9%85%B8%E8%84%AB%E6%B0%AB%E9%85%B6&action=edit&redlink=1" class="new" title="氨酸脫氫酶(页面不存在)">氨酸脫氫酶</a>(須具備NADH或NADPH)</li> <li><a href="/w/index.php?title=%E5%90%A1%E5%92%AF%E5%95%89-5-%E7%BE%A7%E9%85%B8%E9%82%84%E5%8E%9F%E9%85%B6&action=edit&redlink=1" class="new" title="吡咯啉-5-羧酸還原酶(页面不存在)">吡咯啉-5-羧酸還原酶</a>(須具備NADH或NADPH)</li></ol> <figure class="mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/File:Betain-Proline.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Betain-Proline.png/260px-Betain-Proline.png" decoding="async" width="260" height="108" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Betain-Proline.png/390px-Betain-Proline.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Betain-Proline.png/520px-Betain-Proline.png 2x" data-file-width="2945" data-file-height="1224" /></a><figcaption><a href="/w/index.php?title=Zwitterion&action=edit&redlink=1" class="new" title="Zwitterion(页面不存在)">Zwitterion</a>ic structure of both proline enantiomers: (<i>S</i>)-proline (left) and (<i>R</i>)-proline</figcaption></figure> <div class="mw-heading mw-heading2"><h2 id="蛋白質結構的特性"><span id=".E8.9B.8B.E7.99.BD.E8.B3.AA.E7.B5.90.E6.A7.8B.E7.9A.84.E7.89.B9.E6.80.A7"></span>蛋白質結構的特性</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=2" title="编辑章节:蛋白質結構的特性"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>脯氨酸側鏈的獨特環狀結構,使脯氨酸相對於其他氨基酸具有特殊構象剛性,它也影響了脯氨酸和其他氨基酸之間肽鍵形成的速率,當脯氨酸在一個肽鍵中被綁定作為酰胺時,其氮原子未綁定到任何的氫原子,則它不能作為<a href="/wiki/%E6%B0%AB%E9%8D%B5" class="mw-redirect" title="氫鍵">氫鍵</a>供體,但可以是氫鍵受體。 </p><p>Pro-tRNA<sup>Pro</sup>的肽鍵形成相較於其他tRNA相當的緩慢,此為N-烷基氨基羧酸一般的特徵,<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> tRNA和脯氨酸鍵結端部之間肽鍵的形成也相當緩慢,在所有脯氨酸鍵結和脯氨酸鍵結之間的創造是速度最慢的。<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>脯氨酸的特殊構象剛性影響蛋白質的<a href="/wiki/%E4%BA%8C%E7%B4%9A%E7%B5%90%E6%A7%8B" title="二級結構">二級結構</a>,其蛋白質鄰近於一個脯氨酸殘基,而使脯氨酸在<a href="/wiki/%E5%97%9C%E7%86%B1%E7%94%9F%E7%89%A9" title="嗜熱生物">嗜熱生物</a>蛋白質中的高發病率,蛋白質的<a href="/wiki/%E4%BA%8C%E7%B4%9A%E7%B5%90%E6%A7%8B" title="二級結構">二級結構</a>可以<a href="/w/index.php?title=%E5%85%A9%E9%9D%A2%E8%A7%92%CF%86%EF%BC%8C%CF%88&action=edit&redlink=1" class="new" title="兩面角φ,ψ(页面不存在)">兩面角φ,ψ</a>和蛋白質主鏈ω表示,脯氨酸側鏈的鎖環結構的夾角φ約-60℃。 </p><p>脯氨酸在正規<a href="/wiki/%E4%BA%8C%E7%B4%9A%E7%B5%90%E6%A7%8B" title="二級結構">二級結構</a>元素中間為結構性干擾物,如<a href="/wiki/%CE%91%E8%9E%BA%E6%97%8B" title="Α螺旋">α螺旋</a>和<a href="/w/index.php?title=%CE%92%E7%89%87%E5%B1%A4&action=edit&redlink=1" class="new" title="Β片層(页面不存在)">β片層</a>,脯氨酸是<a href="/wiki/%CE%91%E8%9E%BA%E6%97%8B" title="Α螺旋">α螺旋</a>常見的第一個殘基,也同時是<a href="/w/index.php?title=%CE%92%E7%89%87%E5%B1%A4&action=edit&redlink=1" class="new" title="Β片層(页面不存在)">β片層</a>的邊緣鏈,脯氨酸也常發現於<a href="/w/index.php?title=%E5%8C%9D%E6%95%B8&action=edit&redlink=1" class="new" title="匝數(页面不存在)">匝數</a>(另一種二級結構)中,且有助於β匝數的形成,儘管具有一個完整的<a href="/wiki/%E8%84%82%E8%82%AA%E6%97%8F" class="mw-redirect" title="脂肪族">脂肪族</a>側鏈,脯氨酸通常暴露於溶劑之外。 </p><p>一排中的多個脯氨酸和/或<a href="/w/index.php?title=%E7%BE%A5%E5%9F%BA%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&redlink=1" class="new" title="羥基脯氨酸(页面不存在)">羥基脯氨酸</a>可以創造一個<a href="/wiki/%E8%81%9A%E8%84%AF%E6%B0%A8%E9%85%B8%E8%9E%BA%E6%97%8B" title="聚脯氨酸螺旋">聚脯氨酸螺旋</a>,聚脯氨酸螺旋是<a href="/wiki/%E8%86%A0%E5%8E%9F" class="mw-redirect" title="膠原">膠原</a>中的主要<a href="/wiki/%E4%BA%8C%E7%B4%9A%E7%B5%90%E6%A7%8B" title="二級結構">二級結構</a>,脯氨酸經由<a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B0%E7%BE%A5%E5%8C%96%E9%85%B6&action=edit&redlink=1" class="new" title="脯氨酰羥化酶(页面不存在)">脯氨酰羥化酶</a>(或其它添加的吸電子取代基,如<a href="/wiki/%E6%B0%9F" title="氟">氟</a>)的<a href="/wiki/%E7%BE%9F%E5%9F%BA%E5%8C%96" title="羟基化">羥基化</a>,顯著增加<a href="/wiki/%E8%86%A0%E5%8E%9F%E8%9B%8B%E7%99%BD" title="膠原蛋白">膠原蛋白</a>的構象穩定性。<sup id="cite_ref-SzpakJAS_7-0" class="reference"><a href="#cite_note-SzpakJAS-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> 因此,脯氨酸的羥基化是一個關鍵生化過程,用以維持高等生物體的<a href="/wiki/%E7%B5%90%E7%B7%A0%E7%B5%84%E7%B9%94" class="mw-redirect" title="結締組織">結締組織</a>,嚴重疾病如<a href="/wiki/%E6%95%97%E8%A1%80%E7%97%87" title="敗血症">敗血症</a>,可導致羥基化的缺陷,例如在酶脯氨酰羥化酶中突變或缺乏必要的<a href="/w/index.php?title=%E6%8A%97%E5%A3%9E%E8%A1%80%E9%85%B8%EF%BC%88%E7%B6%AD%E7%94%9F%E7%B4%A0C%EF%BC%89&action=edit&redlink=1" class="new" title="抗壞血酸(維生素C)(页面不存在)">抗壞血酸(維生素C)</a>輔助因子。 </p><p>脯氨酸和<a href="/wiki/2-%E6%B0%A8%E5%9F%BA%E5%BC%82%E4%B8%81%E9%85%B8" title="2-氨基异丁酸">2-氨基異丁酸</a>(AIB)的序列也可以形成一個螺旋圈結構。<style data-mw-deduplicate="TemplateStyles:r83946278">.mw-parser-output .template-facttext{background-color:var(--background-color-neutral,#eaecf0);color:inherit;margin:-.3em 0;padding:.3em 0}</style><sup class="noprint Template-Fact"><a href="/wiki/Wikipedia:%E5%88%97%E6%98%8E%E6%9D%A5%E6%BA%90" title="Wikipedia:列明来源"><span style="white-space: nowrap;" title="来源请求。">[來源請求]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="順反異構物"><span id=".E9.A0.86.E5.8F.8D.E7.95.B0.E6.A7.8B.E7.89.A9"></span>順反異構物</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=3" title="编辑章节:順反異構物"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>同大多數氨基酸肽鍵採用<a href="/wiki/%E5%8F%8D%E5%BC%8F%E7%95%B0%E6%A7%8B%E9%AB%94" class="mw-redirect" title="反式異構體">反式異構體</a>(非應變條件下通常為99.9%)不同,脯氨酸和其它N-取代的氨基酸(如<a href="/wiki/%E8%82%8C%E6%B0%A8%E9%85%B8" title="肌氨酸">肌氨酸</a>)的<a href="/wiki/%E8%82%BD%E9%8D%B5" class="mw-redirect" title="肽鍵">肽鍵</a>既能形成<a href="/wiki/%E9%A1%BA%E5%BC%8F" class="mw-redirect" title="顺式">順式</a>異構物也能形成<a href="/wiki/%E5%8F%8D%E5%BC%8F" class="mw-redirect" title="反式">反式</a>異構物。这是因为在大多數氨基酸中,反式異構體比顺式异构体具有更小的空間位阻斥力,然而在X-Pro肽鍵的“順”“反”異構物(X表示任何氨基酸)中,相鄰取代基的空间位阻幾乎相同。因此,X-Pro的肽鍵在非應變條件下,其“順式”異構體的比例可以达到10-40%,这一比例輕微依賴於前面氨基酸的类型,特别是具有芳香族殘基的氨基酸有利於使其成為“順式”異構物。 </p><p>從動力學的角度來看,脯氨酸的“順”-“反”<a href="/wiki/%E7%95%B0%E6%A7%8B%E5%8C%96" class="mw-redirect" title="異構化">異構化</a>是一個非常緩慢的過程,这一过程可以通过捕獲一個或多個脯氨酸關鍵殘基,从而阻礙非自然異構物的<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8%E6%8A%98%E5%8F%A0" title="蛋白质折叠">蛋白質折疊</a>,特别是當自然蛋白質需要“順式”異構物時。这是因為當脯氨酸殘基在核糖體中只能被合成為反式构象。所有生物體都需要利用脯氨酰異構酶催化異構化,而一些<a href="/wiki/%E7%B4%B0%E8%8F%8C" class="mw-redirect" title="細菌">細菌</a>具有專門的與<a href="/wiki/%E6%A0%B8%E7%B3%96%E9%AB%94" class="mw-redirect" title="核糖體">核糖體</a>有關的<a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B0%E7%95%B0%E6%A7%8B%E9%85%B6&action=edit&redlink=1" class="new" title="脯氨酰異構酶(页面不存在)">脯氨酰異構酶</a>。然而,脯氨酸並非对所有的折疊都是必須的,儘管具有許多X-脯肽鍵的非天然異構物的蛋白質是以正常的速率進行折疊的。 </p> <div class="mw-heading mw-heading2"><h2 id="用途"><span id=".E7.94.A8.E9.80.94"></span>用途</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=4" title="编辑章节:用途"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>脯氨酸和其衍生物通常在有機反應中當作對稱催化劑,<a href="/wiki/CBS%E8%BF%98%E5%8E%9F%E5%8F%8D%E5%BA%94" class="mw-redirect" title="CBS还原反应">CBS还原反应</a>和脯氨酸被催化<a href="/wiki/%E7%BE%9F%E9%86%9B%E7%BC%A9%E5%90%88%E5%8F%8D%E5%BA%94" class="mw-redirect" title="羟醛缩合反应">羥醛縮合反應</a>是突出的例子。 </p><p><small>L</small>-脯氨酸是一種<a href="/w/index.php?title=%E6%BB%B2%E9%80%8F%E4%BF%9D%E8%AD%B7%E5%8A%91&action=edit&redlink=1" class="new" title="滲透保護劑(页面不存在)">滲透保護劑</a>,因此可用於多種藥物,生物技術的應用。 </p><p>在釀造時,蛋白質富含和多酚結合的脯氨酸,可產生霧度(濁度)。<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="特色"><span id=".E7.89.B9.E8.89.B2"></span>特色</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=5" title="编辑章节:特色"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>脯氨酸是不符合典型的<a href="/wiki/%E6%8B%89%E6%B0%8F%E5%9B%BE" title="拉氏图">拉氏图</a>的两种氨基酸之一,另一个是甘氨酸。由於連接β碳原子的環形成時,肽鍵的ψ和φ角度有較少允許度的旋轉,因此,它經常被發現於蛋白質的“匝數”當其自由熵(ΔS)比其他氨基酸大,因此在折疊的形式與未折疊的形式的比較中熵的變化較少,此外,脯氨酸的α和β結構很少被發現,因為其側鏈上α-N只能形成一個氫鍵,它會降低結構的穩定性。 </p><p>此外,脯氨酸是唯一的在<a href="/wiki/%E8%89%B2%E8%B0%B1%E6%B3%95" title="色谱法">色谱法</a>中使用<a href="/wiki/%E8%8C%9A%E4%B8%89%E9%85%AE" title="茚三酮">茚三酮</a>后不形成蓝/紫色的氨基酸,相反,脯氨酸产生橙/黄色。 </p> <div class="mw-heading mw-heading2"><h2 id="歷史"><span id=".E6.AD.B7.E5.8F.B2"></span>歷史</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=6" title="编辑章节:歷史"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>在1990年,<a href="/wiki/%E9%87%8C%E5%A4%8F%E5%BE%B7%C2%B7%E7%BB%B4%E5%B0%94%E6%96%BD%E6%B3%B0%E7%89%B9" title="里夏德·维尔施泰特">里夏德·维尔施泰特(Richard Willstätter)</a>透過<a href="/wiki/%E4%B8%99%E4%BA%8C%E9%85%B8%E4%BA%8C%E4%B9%99%E9%85%AF" title="丙二酸二乙酯">丙二酸二乙酯</a>的鈉鹽與<a href="/w/index.php?title=1,3_-%E4%BA%8C%E6%BA%B4%E4%B8%99%E7%83%B7&action=edit&redlink=1" class="new" title="1,3 -二溴丙烷(页面不存在)">1,3 -二溴丙烷</a>的反應合成脯氨酸。在1901年, <a href="/wiki/%E8%B5%AB%E5%B0%94%E6%9B%BC%C2%B7%E5%9F%83%E7%B1%B3%E5%B0%94%C2%B7%E8%B4%B9%E6%AD%87%E5%B0%94" title="赫尔曼·埃米尔·费歇尔">赫尔曼·埃米尔·费歇尔</a>(Hermann Emil Fischer)從酪蛋白和γ-鄰苯二甲酰-propylmalonic酯的分解產物分離脯氨酸。<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="合成"><span id=".E5.90.88.E6.88.90"></span>合成</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=7" title="编辑章节:合成"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/%E5%A4%96%E6%B6%88%E6%97%8B%E6%B7%B7%E5%90%88%E7%89%A9" class="mw-redirect" title="外消旋混合物">外消旋混合物</a>脯氨酸可以从<a href="/wiki/%E4%B8%99%E4%BA%8C%E9%85%B8%E4%BA%8C%E4%B9%99%E9%85%AF" title="丙二酸二乙酯">丙二酸二乙酯</a>和<a href="/wiki/%E4%B8%99%E7%83%AF%E8%85%88" title="丙烯腈">丙烯腈</a>被合成:<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <dl><dd><span typeof="mw:File"><a href="/wiki/File:DL-Proline_synth.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/DL-Proline_synth.png/500px-DL-Proline_synth.png" decoding="async" width="500" height="254" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/DL-Proline_synth.png/750px-DL-Proline_synth.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c2/DL-Proline_synth.png/1000px-DL-Proline_synth.png 2x" data-file-width="2266" data-file-height="1153" /></a></span><div style="clear:left;"></div></dd></dl> <div class="mw-heading mw-heading2"><h2 id="参考文献"><span id=".E5.8F.82.E8.80.83.E6.96.87.E7.8C.AE"></span>参考文献</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=8" title="编辑章节:参考文献"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" 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(<a rel="nofollow" class="external text" href="http://uwo.academia.edu/PaulSzpak/Papers/827788/Fish_Bone_Chemistry_and_Ultrastructure_Implications_for_Taphonomy_and_Stable_Isotope_Analysis">原始内容</a>存档于2012-01-18).</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E8%84%AF%E6%B0%A8%E9%85%B8&rft.atitle=Fish+bone+chemistry+and+ultrastructure%3A+implications+for+taphonomy+and+stable+isotope+analysis&rft.aufirst=Paul&rft.aulast=Szpak&rft.date=2011&rft.genre=article&rft.issue=12&rft.jtitle=Journal+of+Archaeological+Science&rft.pages=3358-3372&rft.volume=38&rft_id=http%3A%2F%2Fuwo.academia.edu%2FPaulSzpak%2FPapers%2F827788%2FFish_Bone_Chemistry_and_Ultrastructure_Implications_for_Taphonomy_and_Stable_Isotope_Analysis&rft_id=info%3Adoi%2F10.1016%2Fj.jas.2011.07.022&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text">K.J. Siebert, "Haze and Foam",<cite class="citation web"><a rel="nofollow" class="external text" href="http://www.nysaes.cornell.edu/fst/faculty/siebert/haze.html">存档副本</a>. <span class="reference-accessdate"> [<span class="nowrap">2010-07-13</span>]</span>. (原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20100711180909/http://www.nysaes.cornell.edu/fst/faculty/siebert/haze.html">存档</a>于2010-07-11).</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E8%84%AF%E6%B0%A8%E9%85%B8&rft.btitle=%E5%AD%98%E6%A1%A3%E5%89%AF%E6%9C%AC&rft.genre=unknown&rft_id=http%3A%2F%2Fwww.nysaes.cornell.edu%2Ffst%2Ffaculty%2Fsiebert%2Fhaze.html&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span> Accessed July 12, 2010.</span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><cite id="CITEREFR.H.A._Plimmer1912" class="citation">R.H.A. Plimmer, R.H.A. Plimmer & F.G. Hopkins , 编, <a rel="nofollow" class="external text" href="http://books.google.com/?id=7JM8AAAAIAAJ&pg=PA130">The chemical composition of the proteins</a>, Monographs on biochemistry, Part I. Analysis 2nd, London: Longmans, Green and Co.: 130, 1912 [1908] <span class="reference-accessdate"> [<span class="nowrap">September 20,</span> 2010]</span></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E8%84%AF%E6%B0%A8%E9%85%B8&rft.au=R.H.A.+Plimmer&rft.btitle=The+chemical+composition+of+the+proteins&rft.date=1912&rft.edition=2nd&rft.genre=book&rft.pages=130&rft.place=London&rft.pub=Longmans%2C+Green+and+Co.&rft.series=Monographs+on+biochemistry&rft_id=http%3A%2F%2Fbooks.google.com%2F%3Fid%3D7JM8AAAAIAAJ%26pg%3DPA130&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text">Vogel, <i>Practical Organic Chemistry</i> 5th edition</span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="延伸阅读"><span id=".E5.BB.B6.E4.BC.B8.E9.98.85.E8.AF.BB"></span>延伸阅读</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=9" title="编辑章节:延伸阅读"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r80540462">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .refbegin-100{font-size:100%}</style><div class="refbegin columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2;"> <ul><li><cite id="CITEREFBalbachSchmid2000" class="citation">Balbach, J.; Schmid, F. X., Proline isomerization and its catalysis in protein folding, Pain, R. H. (编), Mechanisms of Protein Folding 2nd, Oxford University Press: 212–49, 2000, <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/0-19-963788-1" title="Special:网络书源/0-19-963788-1"><span title="国际标准书号">ISBN</span> 0-19-963788-1</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E8%84%AF%E6%B0%A8%E9%85%B8&rft.atitle=Proline+isomerization+and+its+catalysis+in+protein+folding&rft.au=Schmid%2C+F.+X.&rft.aufirst=J.&rft.aulast=Balbach&rft.btitle=Mechanisms+of+Protein+Folding&rft.date=2000&rft.edition=2nd&rft.genre=bookitem&rft.isbn=0-19-963788-1&rft.pages=212-49&rft.pub=Oxford+University+Press&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span>.</li> <li>For a thorough scientific overview of disorders of proline and hydroxyproline metabolism, one can consult chapter 81 of OMMBID <a href="/w/index.php?title=Charles_Scriver&action=edit&redlink=1" class="new" title="Charles Scriver(页面不存在)">Charles Scriver</a>, Beaudet, A.L., Valle, D., Sly, W.S., Vogelstein, B., Childs, B., Kinzler, K.W. (Accessed 2007). <a rel="nofollow" class="external text" href="http://www.ommbid.com">The Online Metabolic and Molecular Bases of Inherited Disease</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20131229104638/http://www.ommbid.com/">页面存档备份</a>,存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>). New York: McGraw-Hill. - Summaries of 255 chapters, full text through many universities. There is also the <a rel="nofollow" class="external text" href="https://web.archive.org/web/20070206171241/http://books.mcgraw-hill.com/medical/ommbid/blog/">OMMBID blog</a>.</li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="参看"><span id=".E5.8F.82.E7.9C.8B"></span>参看</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=10" title="编辑章节:参看"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/%E9%AB%98%E8%84%AF%E6%B0%A8%E9%85%B8%E8%A1%80%E7%97%87" title="高脯氨酸血症">高脯氨酸血症</a></li> <li><a href="/wiki/%E9%81%97%E4%BC%A0%E6%80%A7%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="遗传性代谢缺陷">遗传性代谢缺陷</a></li> <li><a href="/w/index.php?title=Prolidase_deficiency&action=edit&redlink=1" class="new" title="Prolidase deficiency(页面不存在)">Prolidase deficiency</a></li> <li><a href="/w/index.php?title=Prolinol&action=edit&redlink=1" class="new" title="Prolinol(页面不存在)">Prolinol</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="外部链接"><span id=".E5.A4.96.E9.83.A8.E9.93.BE.E6.8E.A5"></span>外部链接</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E8%84%AF%E6%B0%A8%E9%85%B8&action=edit&section=11" title="编辑章节:外部链接"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="英語">(英文)</span><a rel="nofollow" class="external text" href="http://gmd.mpimp-golm.mpg.de/Spectrums/421929e5-2ddf-45bc-a7a3-533eeee502a6.aspx">脯氨酸 MS Spectrum</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20210426210622/http://gmd.mpimp-golm.mpg.de/Spectrums/421929e5-2ddf-45bc-a7a3-533eeee502a6.aspx">页面存档备份</a>,存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>)</li> <li><span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="英語">(英文)</span><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110722050400/http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/AminoAcid/Pro.html">脯氨酸生物合成</a></li> <li><span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="英語">(英文)</span><a rel="nofollow" class="external text" href="http://www.biocarta.com/pathfiles/prolinePathway.asp">脯氨酸生物合成</a> <a href="/wiki/Archive.is" title="Archive.is">Archive.is</a>的<a rel="nofollow" class="external text" href="https://archive.today/20130102005936/http://www.biocarta.com/pathfiles/prolinePathway.asp">存檔</a>,存档日期2013-01-02</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r84265675">.mw-parser-output .hlist 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class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%84%82%E8%82%AA%E6%97%8F%E5%8C%96%E5%90%88%E7%89%A9" title="脂肪族化合物">脂肪族</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E6%94%AF%E9%93%BE%E6%B0%A8%E5%9F%BA%E9%85%B8" title="支链氨基酸">支鏈氨基酸</a> <ul><li><a href="/wiki/%E7%BC%AC%E6%B0%A8%E9%85%B8" title="缬氨酸">纈氨酸</a></li> <li><a href="/wiki/%E7%95%B0%E4%BA%AE%E6%B0%A8%E9%85%B8" title="異亮氨酸">異亮氨酸</a></li> <li><a href="/wiki/%E4%BA%AE%E6%B0%A8%E9%85%B8" title="亮氨酸">亮氨酸</a></li></ul></li> <li><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8" title="甲硫氨酸">甲硫氨酸</a></li> <li><a href="/wiki/%E4%B8%99%E6%B0%A8%E9%85%B8" title="丙氨酸">丙氨酸</a></li> <li><a class="mw-selflink selflink">脯氨酸</a></li> <li><a href="/wiki/%E7%94%98%E6%B0%A8%E9%85%B8" title="甘氨酸">甘氨酸</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%8A%B3%E9%A6%99%E6%97%8F%E6%B0%A8%E5%9F%BA%E9%85%B8" title="芳香族氨基酸">芳香族</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E8%8B%AF%E4%B8%99%E6%B0%A8%E9%85%B8" title="苯丙氨酸">苯丙氨酸</a></li> <li><a href="/wiki/%E9%85%AA%E6%B0%A8%E9%85%B8" title="酪氨酸">酪氨酸</a></li> <li><a href="/wiki/%E8%89%B2%E6%B0%A8%E9%85%B8" title="色氨酸">色氨酸</a></li> <li><a href="/wiki/%E7%B5%84%E6%B0%A8%E9%85%B8" title="組氨酸">組氨酸</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">极性不带电</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E5%A4%A9%E9%97%A8%E5%86%AC%E9%85%B0%E8%83%BA" title="天门冬酰胺">天门冬酰胺</a></li> <li><a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B0%E8%83%BA" title="谷氨酰胺">谷氨酰胺</a></li> <li><a href="/wiki/%E7%B5%B2%E6%B0%A8%E9%85%B8" title="絲氨酸">絲氨酸</a></li> <li><a href="/wiki/%E8%98%87%E6%B0%A8%E9%85%B8" title="蘇氨酸">蘇氨酸</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">带正电(pK<sub>a</sub>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E9%9B%A2%E8%83%BA%E9%85%B8" title="離胺酸">赖氨酸</a>(≈10.8)</li> <li><a href="/wiki/%E7%B2%BE%E6%B0%A8%E9%85%B8" title="精氨酸">精氨酸</a>(≈12.5)</li> <li><a href="/wiki/%E7%B5%84%E6%B0%A8%E9%85%B8" title="組氨酸">組氨酸</a>(≈6.1)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">带负电(pK<sub>a</sub>)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E5%A4%A9%E9%97%A8%E5%86%AC%E6%B0%A8%E9%85%B8" title="天门冬氨酸">天门冬氨酸</a>(≈3.9)</li> <li><a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8" title="谷氨酸">谷氨酸</a>(≈4.1)</li> <li><a href="/wiki/%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="半胱氨酸">半胱氨酸</a>(≈8.3)</li> <li><a href="/wiki/%E9%85%AA%E6%B0%A8%E9%85%B8" title="酪氨酸">酪氨酸</a>(≈10.1)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他分类方法</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E5%BF%85%E9%9C%80%E6%B0%A8%E5%9F%BA%E9%85%B8" title="必需氨基酸">必需胺基酸</a></li> <li><a href="/wiki/%E7%94%9F%E9%85%AE%E6%B0%A8%E5%9F%BA%E9%85%B8" title="生酮氨基酸">生酮胺基酸</a></li> <li><a href="/wiki/%E7%94%9F%E7%B3%96%E6%B0%A8%E5%9F%BA%E9%85%B8" title="生糖氨基酸">生糖胺基酸</a></li> <li><a href="/wiki/%E9%9D%9E%E8%9B%8B%E7%99%BD%E8%83%BA%E5%9F%BA%E9%85%B8" title="非蛋白胺基酸">非蛋白胺基酸</a></li></ul> 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href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6" title="生物化学">生物化學物質</a><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">種類</a>索引</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E7%B3%96%E7%B1%BB" title="Template:糖类">糖类</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E9%86%87" title="Template:醇">醇類</a></li> <li><a href="/wiki/Template:%E5%A4%9A%E5%85%83%E9%86%87" title="Template:多元醇">糖醇</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">醣蛋白</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%8B%B7" title="Template:糖苷">苷</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E8%84%82%E7%B1%BB" title="Template:脂类">酯質</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E7%B1%BB%E8%8A%B1%E7%94%9F%E9%85%B8%E7%B1%BB" title="Template:类花生酸类">类花生酸类</a></li> <li><a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8" title="Template:脂肪酸">脂肪酸</a> <ul><li><a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:脂肪酸代谢中间产物">中間物</a></li></ul></li> <li><a href="/wiki/Template:Glycerides" title="Template:Glycerides">甘油酯</a></li> <li><a href="/wiki/Template:%E7%A3%B7%E8%84%82" title="Template:磷脂">磷脂</a></li> <li><a href="/wiki/Template:%E9%9E%98%E8%84%82" title="Template:鞘脂">鞘脂類</a></li> <li><a href="/wiki/Template:%E8%83%86%E5%9B%BA%E9%86%87%E4%B8%8E%E7%94%BE%E4%BD%93%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:胆固醇与甾体中间产物">胆固醇与甾体中间产物</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E6%A0%B8%E9%85%B8" title="Template:核酸">核酸</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E7%A2%B1%E5%9F%BA%E3%80%81%E6%A0%B8%E8%8B%B7%E5%92%8C%E6%A0%B8%E8%8B%B7%E9%85%B8" title="Template:碱基、核苷和核苷酸">成分</a> <ul><li><a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:核苷酸代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E8%9B%8B%E7%99%BD%E8%B4%A8" title="Template:蛋白质">蛋白質</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8" title="Template:氨基酸">胺基酸</a> <ul><li><a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E5%9B%9B%E5%90%A1%E5%92%AF" title="Template:四吡咯">四吡咯</a> <ul><li><a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84265675"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84261037"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84265675"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84244141"></div><div role="navigation" class="navbox" aria-labelledby="氨基酸代谢代謝中間產物" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="collapsible-title navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84265675"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84244141"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物"><abbr title="查看该模板">查</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template talk:氨基酸代谢中间产物"><abbr title="讨论该模板">论</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:%E7%BC%96%E8%BE%91%E9%A1%B5%E9%9D%A2/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Special:编辑页面/Template:氨基酸代谢中间产物"><abbr title="编辑该模板">编</abbr></a></li></ul></div><div id="氨基酸代谢代謝中間產物" style="font-size:110%;margin:0 5em"><a href="/wiki/%E6%B0%A8%E5%9F%BA%E9%85%B8" title="氨基酸">氨基酸</a><a href="/wiki/%E6%B0%A8%E5%9F%BA%E9%85%B8%E5%90%88%E6%88%90" title="氨基酸合成">代谢</a><a href="/wiki/%E4%BB%A3%E8%AC%9D%E4%B8%AD%E9%96%93%E7%94%A2%E7%89%A9" title="代謝中間產物">代謝中間產物</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%9F%E9%85%AE%E6%B0%A8%E5%9F%BA%E9%85%B8" title="生酮氨基酸">生酮氨基酸</a>→<a href="/wiki/%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A" title="乙酰辅酶A">乙酰辅酶A</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E9%9B%A2%E8%83%BA%E9%85%B8" title="離胺酸">赖氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E9%85%B5%E6%AF%8D%E6%B0%A8%E9%85%B8" title="酵母氨酸">酵母氨酸</a></li> <li><a href="/wiki/%E9%98%BF%E9%9B%A2%E8%83%BA%E9%85%B8" title="阿離胺酸">ε-醛赖氨酸</a></li> <li><a href="/wiki/%CE%91-%E6%B0%A8%E5%9F%BA%E5%B7%B1%E4%BA%8C%E9%85%B8" title="Α-氨基己二酸">α-氨基己二酸</a></li> <li><a href="/wiki/%CE%91-%E9%85%AE%E5%B7%B1%E4%BA%8C%E9%85%B8" title="Α-酮己二酸">α-酮己二酸</a></li> <li><a href="/w/index.php?title=%E6%88%8A%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="戊二酰辅酶A(页面不存在)">戊二酰辅酶A</a></li> <li><a href="/w/index.php?title=%E6%88%8A%E7%83%AF%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="戊烯二酰辅酶A(页面不存在)">戊烯二酰辅酶A</a></li> <li><a href="/w/index.php?title=%E5%B7%B4%E8%B1%86%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="巴豆酰辅酶A(页面不存在)">巴豆酰辅酶A</a></li> <li><a href="/w/index.php?title=%CE%92-%E7%BE%9F%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="Β-羟丁酰辅酶A(页面不存在)">β-羟丁酰辅酶A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E4%BA%AE%E6%B0%A8%E9%85%B8" title="亮氨酸">亮氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%CE%91-%E9%85%AE%E5%BC%82%E5%B7%B1%E9%85%B8" title="Α-酮异己酸">α-酮异己酸</a></li> <li><a href="/w/index.php?title=%E5%BC%82%E6%88%8A%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="异戊酰辅酶A(页面不存在)">异戊酰辅酶A</a></li> <li><a href="/w/index.php?title=%E7%94%B2%E5%9F%BA%E5%B7%B4%E8%B1%86%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="甲基巴豆酰辅酶A(页面不存在)">3-甲基巴豆酰辅酶A</a></li> <li><a href="/w/index.php?title=3-%E7%94%B2%E5%9F%BA%E6%88%8A%E7%83%AF%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="3-甲基戊烯二酰辅酶A(页面不存在)">3-甲基戊烯二酰辅酶A</a></li> <li><a href="/wiki/%E7%BE%9F%E7%94%B2%E5%9F%BA%E6%88%8A%E4%BA%8C%E9%85%B8%E5%8D%95%E9%85%B0%E8%BE%85%E9%85%B6A" title="羟甲基戊二酸单酰辅酶A">β-羟-β-甲戊二酸单酰辅酶A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%89%B2%E6%B0%A8%E9%85%B8" title="色氨酸">色氨酸</a>→<a href="/wiki/%E4%B8%99%E6%B0%A8%E9%85%B8" title="丙氨酸">丙氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=N%27-%E7%94%B2%E9%85%B0%E7%8A%AC%E5%B0%BF%E6%B0%A8%E9%85%B8&action=edit&redlink=1" class="new" title="N'-甲酰犬尿氨酸(页面不存在)"><i>N'</i>-甲酰犬尿氨酸</a> <ul><li><a href="/wiki/%E7%8A%AC%E5%B0%BF%E6%B0%A8%E9%85%B8" title="犬尿氨酸">犬尿氨酸</a></li> <li><a href="/wiki/%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8" title="邻氨基苯甲酸">邻氨基苯甲酸</a></li> <li><a href="/wiki/3-%E7%BE%9F%E5%9F%BA%E7%8A%AC%E5%B0%BF%E6%B0%A8%E9%85%B8" title="3-羟基犬尿氨酸">3-羟基犬尿氨酸</a></li> <li><a href="/w/index.php?title=3-%E7%BE%9F%E5%9F%BA-2-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8&action=edit&redlink=1" class="new" title="3-羟基-2-氨基苯甲酸(页面不存在)">3-羟基-2-氨基苯甲酸</a></li> <li><a href="/wiki/2-%E6%B0%A8%E5%9F%BA-3-%E7%BE%A7%E5%9F%BA%E7%B2%98%E5%BA%B7%E9%85%B8%E5%8D%8A%E9%86%9B" title="2-氨基-3-羧基粘康酸半醛">2-氨基-3-羧基粘康酸半醛</a></li> <li><a href="/wiki/2-%E6%B0%A8%E5%9F%BA%E7%B2%98%E5%BA%B7%E9%85%B8%E5%8D%8A%E9%86%9B" title="2-氨基粘康酸半醛">2-氨基粘康酸半醛</a></li> <li><a href="/wiki/2-%E6%B0%A8%E5%9F%BA%E7%B2%98%E5%BA%B7%E9%85%B8" title="2-氨基粘康酸">2-氨基粘康酸</a></li> <li><a href="/w/index.php?title=%E6%88%8A%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="戊二酰辅酶A(页面不存在)">戊二酰辅酶A</a></li></ul></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%9F%E7%B3%96%E6%B0%A8%E5%9F%BA%E9%85%B8" title="生糖氨基酸">生糖氨基酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E4%B8%99%E9%85%AE%E9%85%B8" title="丙酮酸">丙酮酸</a>→<a href="/wiki/%E6%9F%A0%E6%AA%AC%E9%85%B8" class="mw-redirect" title="柠檬酸">柠檬酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="甘氨酸→絲氨酸→" scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%98%E6%B0%A8%E9%85%B8" title="甘氨酸">甘氨酸</a>→<a href="/wiki/%E7%B5%B2%E6%B0%A8%E9%85%B8" title="絲氨酸">絲氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/3-%E7%A3%B7%E9%85%B8%E7%94%98%E6%B2%B9%E9%85%B8" title="3-磷酸甘油酸">3-磷酸甘油酸</a><br /> <p><a href="/wiki/%E7%94%98%E6%B0%A8%E9%85%B8" title="甘氨酸">甘氨酸</a>→<a href="/wiki/%E8%82%8C%E9%85%B8" title="肌酸">肌酸</a>:<a href="/wiki/%E8%83%8D%E5%9F%BA%E4%B9%99%E9%85%B8" title="胍基乙酸">胍基乙酸</a> </p> <ul><li><a href="/w/index.php?title=%E7%A3%B7%E9%85%B8%E8%82%8C%E9%85%B8&action=edit&redlink=1" class="new" title="磷酸肌酸(页面不存在)">磷酸肌酸</a></li> <li><a href="/wiki/%E8%82%8C%E9%85%B8%E9%85%90" title="肌酸酐">肌酸酐</a></li></ul></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8" title="谷氨酸">谷氨酸</a>→<br /><a href="/wiki/%CE%91-%E9%85%AE%E6%88%8A%E4%BA%8C%E9%85%B8" title="Α-酮戊二酸">α-酮戊二酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%BB%84%E6%B0%A8%E9%85%B8" class="mw-redirect" title="组氨酸">组氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <li><a href="/wiki/%E5%B0%BF%E5%88%8A%E9%85%B8" title="尿刊酸">尿刊酸</a></li> <li><a href="/wiki/%E5%92%AA%E5%94%91-4-%E9%85%AE-5-%E4%B8%99%E9%85%B8" title="咪唑-4-酮-5-丙酸">咪唑-4-酮-5-丙酸</a></li> <li><a href="/wiki/%E8%83%BA%E4%BA%9A%E7%94%B2%E5%9F%BA%E8%B0%B7%E6%B0%A8%E9%85%B8" title="胺亚甲基谷氨酸">胺亚甲基谷氨酸</a></li> <li><a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8-1-%E5%8D%8A%E9%86%9B" title="谷氨酸-1-半醛">谷氨酸-1-半醛</a></li> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a class="mw-selflink selflink">脯氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=1-%E5%90%A1%E5%92%AF%E5%95%89-5-%E7%BE%A7%E9%85%B8&action=edit&redlink=1" class="new" title="1-吡咯啉-5-羧酸(页面不存在)">1-吡咯啉-5-羧酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%B2%BE%E6%B0%A8%E9%85%B8" title="精氨酸">精氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E9%B3%A5%E8%83%BA%E9%85%B8" title="鳥胺酸">鸟氨酸</a></li> <li><a href="/wiki/%E8%85%90%E8%83%BA" title="腐胺">腐胺</a></li> <li><a href="/w/index.php?title=%E8%83%8D%E5%9F%BA%E4%B8%81%E8%83%BA&action=edit&redlink=1" class="new" title="胍基丁胺(页面不存在)">胍基丁胺</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="半胱氨酸">半胱氨酸</a>+<a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8" title="谷氨酸">谷氨酸</a>→<a href="/wiki/%E8%B0%B7%E8%83%B1%E7%94%98%E8%82%BD" title="谷胱甘肽">谷胱甘肽</a>:<a href="/w/index.php?title=%CE%93-%E8%B0%B7%E6%B0%A8%E9%85%B0%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&redlink=1" class="new" title="Γ-谷氨酰半胱氨酸(页面不存在)">γ-谷氨酰半胱氨酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E4%B8%99%E9%85%B0%E8%BE%85%E9%85%B6A" title="丙酰辅酶A">丙酰辅酶A</a>→<br /><a href="/wiki/%E7%90%A5%E7%8F%80%E9%85%B0%E8%BE%85%E9%85%B6A" title="琥珀酰辅酶A">琥珀酰辅酶A</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%BC%AC%E6%B0%A8%E9%85%B8" title="缬氨酸">缬氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%CE%91-%E9%85%AE%E5%BC%82%E6%88%8A%E9%85%B8" title="Α-酮异戊酸">α-酮异戊酸</a></li> <li><a href="/wiki/%E5%BC%82%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A" title="异丁酰辅酶A">异丁酰辅酶A</a></li> <li><a href="/wiki/%E7%94%B2%E5%9F%BA%E4%B8%99%E7%83%AF%E9%85%B0%E8%BE%85%E9%85%B6A" title="甲基丙烯酰辅酶A">甲基丙烯酰辅酶A</a></li> <li><a href="/wiki/3-%E7%BE%9F%E5%BC%82%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A" title="3-羟异丁酰辅酶A">3-羟异丁酰辅酶A</a></li> <li><a href="/wiki/3-%E7%BE%9F%E5%9F%BA%E5%BC%82%E4%B8%81%E9%85%B8" title="3-羟基异丁酸">3-羟基异丁酸</a></li> <li><a href="/wiki/2-%E7%94%B2%E5%9F%BA-3-%E6%B0%A7%E4%BB%A3%E4%B8%99%E9%85%B8" title="2-甲基-3-氧代丙酸">2-甲基-3-氧代丙酸</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E5%BC%82%E4%BA%AE%E6%B0%A8%E9%85%B8" class="mw-redirect" title="异亮氨酸">异亮氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/2,3-%E4%BA%8C%E7%BE%9F%E5%9F%BA-3-%E7%94%B2%E5%9F%BA%E6%88%8A%E9%85%B8" title="2,3-二羟基-3-甲基戊酸">2,3-二羟-3-甲基戊酸</a></li> <li><a href="/wiki/2-%E7%94%B2%E5%9F%BA%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A" title="2-甲基丁酰辅酶A">2-甲基丁酰辅酶A</a></li> <li><a href="/w/index.php?title=%E6%83%95%E6%A0%BC%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="惕格酰辅酶A(页面不存在)">惕格酰辅酶A</a></li> <li><a href="/w/index.php?title=2-%E7%94%B2%E5%9F%BA%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="2-甲基乙酰乙酰辅酶A(页面不存在)">2-甲基乙酰乙酰辅酶A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8" title="甲硫氨酸">甲硫氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><i><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8#生成高半胱氨酸" title="甲硫氨酸">生成高半胱氨酸</a>:</i> <a href="/wiki/S-%E8%85%BA%E8%8B%B7%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8" title="S-腺苷甲硫氨酸"><i>S</i>-腺苷甲硫氨酸</a> <ul><li><a href="/wiki/S-%E8%85%BA%E8%8B%B7%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="S-腺苷高半胱氨酸"><i>S</i>-腺苷-<small>L</small>-高半胱氨酸</a></li> <li><a href="/wiki/%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="高半胱氨酸">高半胱氨酸</a><br /></li></ul> <i><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8#转变为半胱氨酸" title="甲硫氨酸">转变为半胱氨酸</a>:</i> <a href="/wiki/%E8%83%B1%E7%A1%AB%E9%86%9A" title="胱硫醚">胱硫醚</a>*<a href="/wiki/%CE%91-%E4%B8%81%E9%85%AE%E9%85%B8" title="Α-丁酮酸">α-丁酮酸</a>+<a href="/wiki/%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="半胱氨酸">半胱氨酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%8B%8F%E6%B0%A8%E9%85%B8" class="mw-redirect" title="苏氨酸">苏氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%CE%91-%E4%B8%81%E9%85%AE%E9%85%B8" title="Α-丁酮酸">α-丁酮酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E4%B8%99%E9%85%B0%E8%BE%85%E9%85%B6A" title="丙酰辅酶A">丙酰辅酶A</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E7%94%B2%E5%9F%BA%E4%B8%99%E4%BA%8C%E9%85%B8%E5%8D%95%E9%85%B0%E8%BE%85%E9%85%B6A" title="甲基丙二酸单酰辅酶A">甲基丙二酰辅酶A</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E5%BB%B6%E8%83%A1%E7%B4%A2%E9%85%B8" title="延胡索酸">延胡索酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%8B%AF%E4%B8%99%E6%B0%A8%E9%85%B8" title="苯丙氨酸">苯丙氨酸</a>→<a href="/wiki/%E9%85%AA%E6%B0%A8%E9%85%B8" title="酪氨酸">酪氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/4-%E7%BE%9F%E8%8B%AF%E4%B8%99%E9%85%AE%E9%85%B8" title="4-羟苯丙酮酸">4-羟苯丙酮酸</a></li> <li><a href="/wiki/%E5%B0%BF%E9%BB%91%E9%85%B8" title="尿黑酸">尿黑酸</a></li> <li><a href="/wiki/4-%E9%A9%AC%E6%9D%A5%E9%85%B0%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B8" title="4-马来酰乙酰乙酸">4-马来酰乙酰乙酸</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E8%8D%89%E9%85%B0%E4%B9%99%E9%85%B8" title="草酰乙酸">草酰乙酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><i>见<a href="/wiki/%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF" title="尿素循环">尿素循环</a></i></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8%E4%BB%A3%E8%B0%A2&action=edit&redlink=1" class="new" title="半胱氨酸代谢(页面不存在)">半胱氨酸代谢</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E5%8D%8A%E8%83%B1%E4%BA%9A%E7%A3%BA%E9%85%B8" title="半胱亚磺酸">半胱氨酸亚磺酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;background:transparent;color:inherit;"><div style="padding:0px;"><table class="navbox-columns-table" style="border-spacing: 0px; text-align:left;width:100%;"><tbody><tr style="vertical-align:top;"><td class="navbox-list" style="padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:#ccf;;width:10em;"><div> <p><a href="/wiki/Template:%E5%8C%BB%E5%AD%A6%E5%AF%BC%E8%88%AA" title="Template:医学导航">医学导航</a>:<a href="/wiki/%E9%81%97%E4%BC%A0%E6%80%A7%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="遗传性代谢缺陷">遗传代谢缺陷</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:white;;width:10em;"><div> <p><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">代谢</a>、<a href="/wiki/Template:%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%8E%AF%E9%85%B6%E7%B1%BB%E4%B8%8E%E7%94%B5%E5%AD%90%E4%BC%A0%E9%80%92%E9%93%BE" title="Template:三羧酸循环酶类与电子传递链">k</a>,<a href="/wiki/Template:%E7%B3%96%E9%85%B5%E8%A7%A3%E9%85%B6%E7%B1%BB" title="Template:糖酵解酶类">c</a>/<a href="/wiki/Template:%E7%B3%96%E5%8E%9F%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:糖原代谢酶类">g</a>/<a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">r</a>/<a href="/wiki/Template:%E6%88%8A%E7%B3%96%E7%A3%B7%E9%85%B8%E9%80%94%E5%BE%84%E9%85%B6%E7%B1%BB" title="Template:戊糖磷酸途径酶类">p</a>/<a href="/wiki/Template:%E9%86%A3%E8%9B%8B%E7%99%BD%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:醣蛋白代謝酶">y</a>/<a href="/wiki/Template:%E8%9B%8B%E7%99%BD%E8%81%9A%E7%B3%96%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:蛋白聚糖代謝酶">i</a>,<a href="/wiki/Template:%E8%84%82%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:脂代谢酶类">f</a>/<a href="/wiki/Template:%E7%A3%B7%E8%84%82%E4%BB%A3%E8%AC%9D" title="Template:磷脂代謝">h</a>/<a href="/wiki/Template:%E8%86%BD%E5%9B%BA%E9%86%87%E8%88%87%E9%A1%9E%E5%9B%BA%E9%86%87%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:膽固醇與類固醇代謝酶">s</a>/<a href="/wiki/Template:%E8%84%82%E8%9B%8B%E7%99%BD%E4%BB%A3%E8%B0%A2" title="Template:脂蛋白代谢">l</a>/<a href="/wiki/Template:%E7%B3%96%E8%84%82%E8%88%87%E9%9E%98%E8%84%82%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:糖脂與鞘脂代謝酶">o</a>/<a href="/wiki/Template:%E9%A1%9E%E8%8A%B1%E7%94%9F%E9%85%B8%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:類花生酸代謝酶">e</a>,<a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:氨基酸代谢酶类">a</a>/<a href="/wiki/Template:%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF%E9%85%B6%E7%B1%BB" title="Template:尿素循环酶类">u</a>,<a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:核苷酸代谢酶类">n</a>,<a href="/wiki/Template:%E5%8D%9F%E5%95%89%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:卟啉代谢酶类">m</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:silver;;width:10em;"><div> <p><a href="/wiki/Template:Disorders_of_TCA_and_ETC" class="mw-redirect" title="Template:Disorders of TCA and ETC">k</a>,<a href="/wiki/Template:%E5%85%88%E5%A4%A9%E6%80%A7%E7%B3%96%E7%B1%BB%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="Template:先天性糖类代谢缺陷">cgrp</a>/<a href="/wiki/Template:Glycoprotein_disorders" title="Template:Glycoprotein disorders">y</a>/<a href="/w/index.php?title=Template:Proteoglycan_disorders&action=edit&redlink=1" class="new" title="Template:Proteoglycan disorders(页面不存在)">i</a>,<a href="/wiki/Template:Fatty-acid_metabolism_disorders" title="Template:Fatty-acid metabolism disorders">f</a>/<a href="/w/index.php?title=Template:Phospholipid_metabolism_disorders&action=edit&redlink=1" class="new" title="Template:Phospholipid metabolism disorders(页面不存在)">h</a>/<a href="/w/index.php?title=Template:Defects_of_cholesterol_and_steroid_metabolism&action=edit&redlink=1" class="new" title="Template:Defects of cholesterol and steroid metabolism(页面不存在)">s</a>/<a href="/wiki/Template:Lipid_metabolism_disorders" title="Template:Lipid metabolism disorders">l</a>/<a href="/wiki/Template:Lipid_storage_disorders" title="Template:Lipid storage disorders">o</a>/<a href="/wiki/Template:Eicosanoid_metabolism_disorders" title="Template:Eicosanoid metabolism disorders">e</a>,<a href="/wiki/Template:Amino_acid_metabolic_pathology" title="Template:Amino acid metabolic pathology">au</a>,<a href="/w/index.php?title=Template:Inborn_errors_of_purine-pyrimidine_metabolism&action=edit&redlink=1" class="new" title="Template:Inborn errors of purine-pyrimidine metabolism(页面不存在)">n</a>,<a href="/w/index.php?title=Template:Heme_metabolism_disorders&action=edit&redlink=1" class="new" title="Template:Heme metabolism disorders(页面不存在)">m</a>,<a href="/wiki/Template:Eponymous_medical_signs_for_endocrinology,_nutrition,_and_metabolism" title="Template:Eponymous medical signs for endocrinology, nutrition, and metabolism">人名体征</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:#ccf;;width:10em;"><div> <p>药物(<a href="/wiki/ATC%E4%BB%A3%E7%A0%81_(A16)" title="ATC代码 (A16)">A16</a>/<a href="/wiki/Template:%E8%A1%80%E8%84%82%E8%B0%83%E8%8A%82%E5%89%82" title="Template:血脂调节剂">C10</a>)、中间产物(<a href="/wiki/Template:%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%92%B0" title="Template:三羧酸循環">k</a>,<a href="/wiki/Template:%E7%B3%96%E9%85%B5%E8%A7%A3" title="Template:糖酵解">c</a>/<a href="/wiki/Template:%E7%B3%96%E5%8E%9F%E7%94%9F%E6%88%90%E4%B8%8E%E7%B3%96%E5%8E%9F%E5%88%86%E8%A7%A3%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:糖原生成与糖原分解代谢中间产物">g</a>/<a href="/wiki/Template:%E6%9E%9C%E7%B3%96%E4%B8%8E%E5%8D%8A%E4%B9%B3%E7%B3%96%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:果糖与半乳糖代谢中间产物">r</a>/<a href="/wiki/Template:%E6%88%8A%E7%B3%96%E7%A3%B7%E9%85%B8%E9%80%94%E5%BE%84%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:戊糖磷酸途径中间产物">p</a>/<a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">y</a>/<a href="/wiki/Template:%E7%B3%96%E8%83%BA%E8%81%9A%E7%B3%96" title="Template:糖胺聚糖">i</a>,<a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:脂肪酸代谢中间产物">f</a>/<a href="/wiki/Template:%E7%A3%B7%E8%84%82" title="Template:磷脂">h</a>/<a href="/wiki/Template:%E8%83%86%E5%9B%BA%E9%86%87%E4%B8%8E%E7%94%BE%E4%BD%93%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:胆固醇与甾体中间产物">s</a>/<a href="/wiki/Template:%E9%9E%98%E8%84%82" title="Template:鞘脂">o</a>/<a href="/w/index.php?title=Template:Eicosanoids&action=edit&redlink=1" class="new" title="Template:Eicosanoids(页面不存在)">e</a>,<a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物">a</a>/<a href="/wiki/Template:%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF" title="Template:尿素循环">u</a>,<a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:核苷酸代谢中间产物">n</a>,<a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">m</a>) </p> </div></td></tr></tbody></table></div></td></tr></tbody></table><div></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="collapsible-title navbox-title" colspan="2"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Template:生物化学物质种类"><abbr title="查看该模板">查</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Template talk:生物化学物质种类"><abbr title="讨论该模板">论</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:%E7%BC%96%E8%BE%91%E9%A1%B5%E9%9D%A2/Template:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Special:编辑页面/Template:生物化学物质种类"><abbr title="编辑该模板">编</abbr></a></li></ul></div><div id="生物化學物質種類索引" style="font-size:110%;margin:0 5em"><a href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6" title="生物化学">生物化學物質</a><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">種類</a>索引</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E7%B3%96%E7%B1%BB" title="Template:糖类">糖类</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E9%86%87" title="Template:醇">醇類</a></li> <li><a href="/wiki/Template:%E5%A4%9A%E5%85%83%E9%86%87" title="Template:多元醇">糖醇</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">醣蛋白</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%8B%B7" title="Template:糖苷">苷</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E8%84%82%E7%B1%BB" title="Template:脂类">酯質</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E7%B1%BB%E8%8A%B1%E7%94%9F%E9%85%B8%E7%B1%BB" title="Template:类花生酸类">类花生酸类</a></li> <li><a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8" title="Template:脂肪酸">脂肪酸</a> <ul><li><a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:脂肪酸代谢中间产物">中間物</a></li></ul></li> <li><a href="/wiki/Template:Glycerides" title="Template:Glycerides">甘油酯</a></li> <li><a href="/wiki/Template:%E7%A3%B7%E8%84%82" title="Template:磷脂">磷脂</a></li> <li><a href="/wiki/Template:%E9%9E%98%E8%84%82" title="Template:鞘脂">鞘脂類</a></li> <li><a href="/wiki/Template:%E8%83%86%E5%9B%BA%E9%86%87%E4%B8%8E%E7%94%BE%E4%BD%93%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:胆固醇与甾体中间产物">胆固醇与甾体中间产物</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E6%A0%B8%E9%85%B8" title="Template:核酸">核酸</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E7%A2%B1%E5%9F%BA%E3%80%81%E6%A0%B8%E8%8B%B7%E5%92%8C%E6%A0%B8%E8%8B%B7%E9%85%B8" title="Template:碱基、核苷和核苷酸">成分</a> <ul><li><a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:核苷酸代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E8%9B%8B%E7%99%BD%E8%B4%A8" title="Template:蛋白质">蛋白質</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8" title="Template:氨基酸">胺基酸</a> <ul><li><a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物">中間物</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E5%9B%9B%E5%90%A1%E5%92%AF" title="Template:四吡咯">四吡咯</a> <ul><li><a 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