Copper-67 | NorthStar Medical Radioisotopes, LLC

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class="section-content "> <section class="h2_header_short"> <div class="container"> <div class="header-inner"> <a href="https://www.northstarnm.com/therapeutics/" class="h2_breadcrumb_link mb-2 white">Radiopharmaceutical Therapy</a> <h1 class="mb-5"><span>Copper-67</span></h1> <div class="h2_intro_box"> <p class="mb-4">Copper-67 (Cu-67) is a short-range, beta-emitting radioisotope which is attractive for medical purposes due to its ability to carry sufficient radiation energy to cause cell death in targeted cells while having a short half-life, limiting unwanted radioactivity in otherwise healthy tissue.</p> <p class="mb-4">We are routinely producing Cu-67 to ensure expanded and reliable supply of this promising radioisotope for the treatment of cancer.</p> </div> </div> <div class="header-img"> <img src="https://www.northstarnm.com/wp-content/uploads/2023/02/Cu-box-green-and-white-01.png" alt="" class="img-fluid w-100" /> </div> </div> </section> <section class="r7_row_multicolumns py-normal-t " > <div class="container"> <div class="row"> <div class="col-12 relative d-flex flex-column "> <div class="row align-items-start "> <div class="col-12 mx-auto"> <div class="video-box"> <a class="modaltrigger1" data-target="#videomodal"><img src="https://www.northstarnm.com/wp-content/uploads/2024/02/copper-still.png" class="w-100 img-fluid mb-5 mb-lg-0" alt="" /></a> <div class="modalhidden" style="display: none;"> <div class="video-container"> <div style="position:relative;padding-bottom:56.25%;overflow:hidden;height:0;max-width:100%;"><iframe id="cccb9da1-8ed4-4c01-872d-e70cbbd27c74" src="https://iframe.dacast.com/vod/aaf2a0fa4f6098082a74d1683a18ff38/cccb9da1-8ed4-4c01-872d-e70cbbd27c74" width="100%" height="100%" frameborder="0" scrolling="no" allow="autoplay;encrypted-media" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen style="position:absolute;top:0;left:0;"></iframe></div> </div> </div> </div> </div> </div> </div> </div> </div> </section> <section class="r7_row_multicolumns py-normal " > <div class="container"> <div class="row"> <div class="col-12 relative d-flex flex-column "> <div class="p-5 bg-white-fade "> <div class="row align-items-center mb-5"> <div class="col-md-8 "> <h2 class="title mb-4 md-blue"> A NOVEL APPROACH<br><span>TO CANCER THERAPY</span> </h2> <div class="copy mb-4 mb-md-0"> <p>Development of Cu-67 has also been hampered by the lack of chelators that securely attach copper to its targeted molecule. Clarity Pharmaceuticals’ Targeted Copper Theranostics platform using chelators that securely hold copper, is now reaching later stage development and commercialization and will treat cancers such as neuroblastoma, breast and prostate.</p> </div>  </div> <div class="col-md-4 text-center"> <div class="featured-img"> <img src="https://www.northstarnm.com/wp-content/uploads/2023/02/logo-clarity.png" class="w-75 img-fluid mb-4" alt="" /> </div> <div class="copy mb-4 mb-md-0"> <p><strong><a class="md-blue" href="https://www.northstarnm.com/northstar-medical-radioisotopes-enters-u-s-supply-agreement-for-commercial-supply-of-therapeutic-radioisotope-copper-67-cu-67-exclusively-to-clarity-pharmaceuticals-for-its-targeted-copper-theranos/">NorthStar is the exclusive Cu-67 commercial supplier to Clarity Pharmaceuticals</a></strong></p> </div>  </div> </div> <div class="row align-items-start "> <div class="col-md-5 "> <div class="copy mb-4 mb-md-0"> <div class="row text-center"> <div class="col-4 col-sm-12 mb-4"><img decoding="async" class="w-50s img-fluid" src="https://www.northstarnm.com/wp-content/uploads/2023/02/b-copper-1.png" /></div> <div class="col-4 col-sm-12 mb-4"><img decoding="async" class="w-50s img-fluid" src="https://www.northstarnm.com/wp-content/uploads/2023/02/b-copper-2.png" /></div> <div class="col-4 col-sm-12 mb-4"><img decoding="async" class="w-50s img-fluid" src="https://www.northstarnm.com/wp-content/uploads/2023/02/b-copper-3.png" /></div> </div> </div>  </div> <div class="col-md-7 "> <h2 class="title mb-4 md-blue"> Scalable, Reliable,<br><span>Domestic Production Processes</span> </h2> <div class="copy mb-4 mb-md-0"> <p>NorthStar’s unique and proprietary electron Accelerator Production facility and processes are designed to provide efficiencies throughout the production process, thereby enabling the production of multiple radioisotopes utilizing the same equipment.</p> <p class="mb-5">Our 30,000 sq. ft. state-of-the- art Accelerator Production facility houses two Rhodotron TT300 Electron Accelerators. This advanced technology will produce clean, commercial quantities of Cu-67 and is environmentally friendly and non-uranium based. The manufacturing process has no long-lived contaminants or byproducts and its starting material, zinc, is readily available. This clean manufacturing process allows for high volume production, with no issues associated with access to stable target material or generation of long-lived radioactive waste.</p> <ul> <li><strong>Unique, proprietary facility and processes designed to provide efficiencies that enable production of multiple radioisotopes utilizing the same equipment</strong></li> <li><strong>Routinely produced using an electron accelerator</strong></li> <li><strong>Beta emitter with a 61.8–hour half-life</strong></li> <li><strong>Cu-67 therapeutic companion to Cu-64 (diagnostic)</strong></li> </ul> </div>  </div> <div class="col-md-5 "> <div class="copy mb-4 mb-md-0"> <div class="mt-5 mt-md-0 row align-items-center"> <div class="col-3"><a href="https://www.northstarnm.com/wp-content/uploads/2024/05/Copper-Sheet-March-2024.pdf" target="_blank" rel="noopener"><img decoding="async" class="w-100 img-fluid" src="https://www.northstarnm.com/wp-content/uploads/2023/02/icon-pdf-b-2.svg" alt="" /></a></div> <div class="col-9"> <div class="download_title md-blue">View</div> <div class="download_desc_lg md-blue">Our Copper-67<br /> Fact Sheet</div> </div> </div> </div>  </div> </div> </div> </div> </div> </div> </section> <section class="r7_row_multicolumns py-normal-b " > <div class="container"> <div class="row"> <div class="col-12 relative d-flex flex-column "> <div class="p-5 bg-white-fade "> <div class="row py-0 align-items-start "> <div class="col-12 text-center"> <div class="copy mb-4 mb-md-0"> <p class="mb-4 blue" style="font-size: 24px; line-height: 1.4; width: 75%; display: inline-block;">Cu-64 SAR-bisPSMA PET/CT imaging before and after a single cycle of 8GBq Cu-67 SAR-bisPSMA (cohort 2)</p> <p><img decoding="async" class="w-100 img-fluid mb-4" src="https://www.northstarnm.com/wp-content/uploads/2023/10/SECuRE-cohort-2.png" alt="" /></p> <p><small class="text-center">(photo courtesy of Clarity Pharmaceuticals)</small></p> </div>  </div> </div> </div> </div> </div> </div> </section> </div> </section> <section class="section-bg " style="background-image: url(https://www.northstarnm.com/wp-content/uploads/2023/02/bg-blue-fade.jpg);" > <div class="section-content "> <section class="module-timeline"> <div class="container"> <div class="row"> <div class="col-md-3"> <h2 class="title mb-4 text-white">TIMELINE</h2> </div> <div class="col-md-9"> <div class="timeline-container theme-white-green-blue"> <div class="timeline-item status-complete"> <div class="timeline-date"> Sept 2019 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Accelerator Production facility groundbreaking </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Jan 2021 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Facility construction completed </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Apr 2021 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Delivery of electron accelerator pair </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Mid 2022 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Electron accelerator pair and associated equipment operational </div> </div> <div class="timeline-item status-complete"> <div class="timeline-date"> Mid 2023 </div> <div class="timeline-status"> <div class="timeline-status-inner"> <i class="fa-sharp fa-solid fa-check"></i> </div> </div> <div class="timeline-content"> Initial production of radiochemical grade Cu-67 </div> </div> </div> </div> </div> </div> </section> </div> </section> 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