CINXE.COM

Home | Gut

<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE html> <html lang="en" dir="ltr" version="HTML+RDFa+MathML 1.1" xmlns:dc="http://purl.org/dc/terms/" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:og="http://ogp.me/ns#" xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:sioc="http://rdfs.org/sioc/ns#" xmlns:sioct="http://rdfs.org/sioc/types#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" xmlns:mml="http://www.w3.org/1998/Math/MathML"> <head profile="http://www.w3.org/1999/xhtml/vocab"> <!--[if IE]><![endif]--> <link rel="dns-prefetch" href="//securepubads.g.doubleclick.net" /> <meta http-equiv="Content-Type" content="text/html; charset=utf-8" /> <meta name="viewport" content="width=device-width, initial-scale=1" /> <link rel="shortcut icon" href="https://gut.bmj.com/sites/default/themes/bmjj/favicon.ico" type="image/vnd.microsoft.icon" /> <meta name="Generator" content="Drupal 7 (http://drupal.org)" /> <script>window.dataLayer = window.dataLayer || [];window.dataLayer.push({"page":{"hwTitle":"Homepage","hwUrl":"https://gut.bmj.com/","hwPath":"/","hwType":"home page"},"user":{"hwMemberID":"","hwLoggedIntoInstitutionID":"","hwLoggedIntoInstitution":"","hwAccessUsageTerms":"guest","hwRegisteredUser":"no","mail":"e3b0c44298fc1c149afbf4c8996fb92427ae41e4649b934ca495991b7852b855"}}); //--><!]]></script> <title>Home | Gut</title> <link type="text/css" rel="stylesheet" href="/sites/default/files/advagg_css/css__-IWYbrSvfMEEUYmKea50heDVX_ylBhGdcqRPlOMB0HU__PyjK4eX3EumdA4Z1YRo-9HliR2NbU3XPgHFQUznnX7g__dGRtyN8GJBuhBvXCmXEhVK4mGQl3ZIewHeJUeSvfyQ0.css" media="all" /> <!-- OneTrust Cookies Consent Notice start --> <script src="https://cookie-cdn.cookiepro.com/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="565e50dd-f6e9-46d6-91cd-5c40a270264f"></script> <script type="text/javascript"> function OnetrustAdsConsent(){ if(googletag.apiReady){ //console.log("GoogleTag API ready") googletag.pubads().disableInitialLoad(); if(OptanonActiveGroups.match(/,4,/)){ googletag.pubads().setRequestNonPersonalizedAds(0); //googletag.pubads().refresh(); } else{ googletag.pubads().setRequestNonPersonalizedAds(1); googletag.pubads().refresh(); } } else{ OnetrustAdsConsent(); } } function OptanonWrapper() { OnetrustAdsConsent(); } </script> <!-- OneTrust Cookies Consent Notice end --> <script type="text/javascript" src="/sites/default/files/advagg_js/js__DdxPgqGimsdUot2QWNz_pGsHzqNGpx6RMCWHpL8YWkg__c6zfK6oHHbLpTal5PdQxeQI3xGoCM8IXWtEHwIZr560__dGRtyN8GJBuhBvXCmXEhVK4mGQl3ZIewHeJUeSvfyQ0.js"></script> <script type="text/javascript" src="https://securepubads.g.doubleclick.net/tag/js/gpt.js"></script> <script type="text/javascript" src="/sites/default/files/advagg_js/js__4-GH3KfBHcTyoDUURg_FpF3dmlavQY9nmjHK0_Hqf-w__t69a_UY8paKhU_BR7ELiYAt92wfO7YP2J8FPynCyHmg__dGRtyN8GJBuhBvXCmXEhVK4mGQl3ZIewHeJUeSvfyQ0.js"></script> <script type="text/javascript" defer="defer" async="async" src="//cdn.foxycart.com/bmjpg.ecommerce.highwire.org/loader.js"></script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- /*! * yepnope1.5.4 * (c) WTFPL, GPLv2 */ (function(a,b,c){function d(a){return"[object Function]"==o.call(a)}function e(a){return"string"==typeof a}function f(){}function g(a){return!a||"loaded"==a||"complete"==a||"uninitialized"==a}function h(){var a=p.shift();q=1,a?a.t?m(function(){("c"==a.t?B.injectCss:B.injectJs)(a.s,0,a.a,a.x,a.e,1)},0):(a(),h()):q=0}function i(a,c,d,e,f,i,j){function k(b){if(!o&&g(l.readyState)&&(u.r=o=1,!q&&h(),l.onload=l.onreadystatechange=null,b)){"img"!=a&&m(function(){t.removeChild(l)},50);for(var d in y[c])y[c].hasOwnProperty(d)&&y[c][d].onload()}}var j=j||B.errorTimeout,l=b.createElement(a),o=0,r=0,u={t:d,s:c,e:f,a:i,x:j};1===y[c]&&(r=1,y[c]=[]),"object"==a?l.data=c:(l.src=c,l.type=a),l.width=l.height="0",l.onerror=l.onload=l.onreadystatechange=function(){k.call(this,r)},p.splice(e,0,u),"img"!=a&&(r||2===y[c]?(t.insertBefore(l,s?null:n),m(k,j)):y[c].push(l))}function j(a,b,c,d,f){return q=0,b=b||"j",e(a)?i("c"==b?v:u,a,b,this.i++,c,d,f):(p.splice(this.i++,0,a),1==p.length&&h()),this}function k(){var a=B;return a.loader={load:j,i:0},a}var l=b.documentElement,m=a.setTimeout,n=b.getElementsByTagName("script")[0],o={}.toString,p=[],q=0,r="MozAppearance"in l.style,s=r&&!!b.createRange().compareNode,t=s?l:n.parentNode,l=a.opera&&"[object Opera]"==o.call(a.opera),l=!!b.attachEvent&&!l,u=r?"object":l?"script":"img",v=l?"script":u,w=Array.isArray||function(a){return"[object Array]"==o.call(a)},x=[],y={},z={timeout:function(a,b){return b.length&&(a.timeout=b[0]),a}},A,B;B=function(a){function b(a){var a=a.split("!"),b=x.length,c=a.pop(),d=a.length,c={url:c,origUrl:c,prefixes:a},e,f,g;for(f=0;f<d;f++)g=a[f].split("="),(e=z[g.shift()])&&(c=e(c,g));for(f=0;f<b;f++)c=x[f](c);return c}function g(a,e,f,g,h){var i=b(a),j=i.autoCallback;i.url.split(".").pop().split("?").shift(),i.bypass||(e&&(e=d(e)?e:e[a]||e[g]||e[a.split("/").pop().split("?")[0]]),i.instead?i.instead(a,e,f,g,h):(y[i.url]?i.noexec=!0:y[i.url]=1,f.load(i.url,i.forceCSS||!i.forceJS&&"css"==i.url.split(".").pop().split("?").shift()?"c":c,i.noexec,i.attrs,i.timeout),(d(e)||d(j))&&f.load(function(){k(),e&&e(i.origUrl,h,g),j&&j(i.origUrl,h,g),y[i.url]=2})))}function h(a,b){function c(a,c){if(a){if(e(a))c||(j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}),g(a,j,b,0,h);else if(Object(a)===a)for(n in m=function(){var b=0,c;for(c in a)a.hasOwnProperty(c)&&b++;return b}(),a)a.hasOwnProperty(n)&&(!c&&!--m&&(d(j)?j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}:j[n]=function(a){return function(){var b=[].slice.call(arguments);a&&a.apply(this,b),l()}}(k[n])),g(a[n],j,b,n,h))}else!c&&l()}var h=!!a.test,i=a.load||a.both,j=a.callback||f,k=j,l=a.complete||f,m,n;c(h?a.yep:a.nope,!!i),i&&c(i)}var i,j,l=this.yepnope.loader;if(e(a))g(a,0,l,0);else if(w(a))for(i=0;i<a.length;i++)j=a[i],e(j)?g(j,0,l,0):w(j)?B(j):Object(j)===j&&h(j,l);else Object(a)===a&&h(a,l)},B.addPrefix=function(a,b){z[a]=b},B.addFilter=function(a){x.push(a)},B.errorTimeout=1e4,null==b.readyState&&b.addEventListener&&(b.readyState="loading",b.addEventListener("DOMContentLoaded",A=function(){b.removeEventListener("DOMContentLoaded",A,0),b.readyState="complete"},0)),a.yepnope=k(),a.yepnope.executeStack=h,a.yepnope.injectJs=function(a,c,d,e,i,j){var k=b.createElement("script"),l,o,e=e||B.errorTimeout;k.src=a;for(o in d)k.setAttribute(o,d[o]);c=j?h:c||f,k.onreadystatechange=k.onload=function(){!l&&g(k.readyState)&&(l=1,c(),k.onload=k.onreadystatechange=null)},m(function(){l||(l=1,c(1))},e),i?k.onload():n.parentNode.insertBefore(k,n)},a.yepnope.injectCss=function(a,c,d,e,g,i){var e=b.createElement("link"),j,c=i?h:c||f;e.href=a,e.rel="stylesheet",e.type="text/css";for(j in d)e.setAttribute(j,d[j]);g||(n.parentNode.insertBefore(e,n),m(c,0))}})(this,document); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- yepnope({ test: Modernizr.matchmedia, nope: '/sites/all/libraries/media-match/media.match.min.js' }); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- ;var googletag=googletag||{};googletag.cmd=googletag.cmd||[];googletag.slots=googletag.slots||{}; //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- googletag.slots["top"] = googletag.defineSlot("/21798771943/GUT-TOP", [[970, 250], [900, 250], [728, 90], [468, 60], [320, 100], [320, 50]], "dfp-ad-top") .addService(googletag.pubads()); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- googletag.slots["bottom"] = googletag.defineSlot("/21798771943/GUT-BOTTOM", [[970, 250], [900, 250], [728, 90], [468, 60], [320, 100], [320, 50]], "dfp-ad-bottom") .addService(googletag.pubads()); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- ;googletag.cmd.push(function(){googletag.pubads().enableAsyncRendering();googletag.pubads().collapseEmptyDivs();googletag.pubads().addEventListener('slotRenderEnded',function(e){if(e.isEmpty){var t=e.slot.getSlotElementId(),g=document.getElementById(t);if(g.parentElement.classList.contains('dfp-tag-wrapper')){g.parentElement.style.display='none'}}});googletag.pubads().setTargeting('url','//');googletag.pubads().setTargeting('page:hwTitle','Homepage');googletag.pubads().setTargeting('page:hwUrl','https://gut.bmj.com/');googletag.pubads().setTargeting('page:hwPath','/');googletag.pubads().setTargeting('page:hwType','home page');googletag.pubads().setTargeting('user:hwAccessUsageTerms','guest');googletag.pubads().setTargeting('user:hwRegisteredUser','no')});googletag.enableServices(); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- jQuery.extend(Drupal.settings, {"basePath":"\/","pathPrefix":"","ajaxPageState":{"theme":"bmjj","theme_token":"mNdyn70rdNk09yF_ntl8v1JJMmQb4W7cL93wLp86Yzo","jquery_version":"1.8","css":{"modules\/system\/system.base.css":1,"modules\/system\/system.menus.css":1,"modules\/system\/system.messages.css":1,"modules\/system\/system.theme.css":1,"sites\/all\/modules\/contrib\/date\/date_api\/date.css":1,"sites\/all\/modules\/contrib\/date\/date_popup\/themes\/datepicker.1.7.css":1,"modules\/field\/theme\/field.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_draw\/css\/highwire-draw.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_folders\/highwire_folders.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_foxycart\/highwire_foxycart.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_responsive\/css\/highwire-responsive.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_saved_searches\/highwire_saved_searches.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_user\/highwire_user.css":1,"sites\/default\/modules\/contrib\/menu_attach_block\/menu_attach_block.css":1,"modules\/node\/node.css":1,"modules\/search\/search.css":1,"modules\/user\/user.css":1,"sites\/all\/modules\/contrib\/views\/css\/views.css":1,"sites\/all\/modules\/contrib\/ckeditor\/css\/ckeditor.css":1,"sites\/all\/modules\/contrib\/colorbox\/styles\/default\/colorbox_style.css":1,"sites\/all\/modules\/contrib\/ctools\/css\/ctools.css":1,"sites\/all\/modules\/contrib\/foxycart\/foxycart.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire.style.highwire.css":1,"sites\/all\/modules\/highwire\/highwire\/css\/nlm-elements.css":1,"sites\/all\/modules\/contrib\/panels\/css\/panels.css":1,"sites\/all\/modules\/highwire\/highwire\/plugins\/content_types\/css\/highwire_reports_feed.css":1,"sites\/all\/modules\/highwire\/highwire\/css\/highwire-article-citation-list.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_responsive\/plugins\/styles\/highwire_responsive_toggle\/highwire_responsive_toggle.css.less":1,"sites\/all\/modules\/highwire\/highwire\/css\/highwire.gtranslate.css":1,"sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_theme_tools\/css\/font-hwicons.css":1,"sites\/all\/modules\/highwire\/highwire\/highwire_theme_tools\/css\/font-hwicons-glyphs.css":1,"sites\/default\/themes\/bmjj\/system.messages.css":1,"sites\/default\/themes\/bmjj\/system.menus.css":1,"sites\/default\/themes\/bmjj\/jquery.bxslider.css":1,"sites\/default\/themes\/bmjj\/css\/base\/normalize.css":1,"sites\/default\/themes\/bmjj\/css\/base\/print.css":1,"sites\/default\/themes\/bmjj\/css\/base\/typography.css":1,"sites\/default\/themes\/bmjj\/css\/layout\/responsive-visibility.css.less":1,"sites\/default\/themes\/bmjj\/css\/layout\/grid\/grid.css.less":1,"sites\/default\/themes\/bmjj\/css\/components\/article.css.less":1,"sites\/default\/themes\/bmjj\/css\/components\/archive.css.less":1,"sites\/default\/themes\/bmjj\/css\/components\/forms.css":1,"sites\/default\/themes\/bmjj\/css\/components\/buttons.css":1,"sites\/default\/themes\/bmjj\/css\/components\/lists.css":1,"sites\/default\/themes\/bmjj\/css\/components\/images.css":1,"sites\/default\/themes\/bmjj\/css\/components\/tables.css":1,"sites\/default\/themes\/bmjj\/css\/components\/code.css":1,"sites\/default\/themes\/bmjj\/css\/components\/highwire\/highwire.style.markup.css":1,"sites\/default\/themes\/bmjj\/css\/components\/jquery.ui\/jquery.ui.theme.css":1,"sites\/default\/themes\/bmjj\/css\/components\/jquery.ui\/tooltip.css":1,"sites\/default\/themes\/bmjj\/css\/components\/jquery.ui\/accordion.css":1,"sites\/default\/themes\/bmjj\/css\/components\/jquery.ui\/dialog.css":1,"sites\/default\/themes\/bmjj\/css\/components\/tabs.css":1,"sites\/default\/themes\/bmjj\/css\/components\/messages.css":1,"sites\/default\/themes\/bmjj\/css\/components\/breadcrumb.css":1,"sites\/default\/themes\/bmjj\/css\/components\/pager.css":1,"sites\/default\/themes\/bmjj\/css\/components\/blocks.css":1,"sites\/default\/themes\/bmjj\/css\/components\/search.css":1,"sites\/default\/themes\/bmjj\/css\/components\/citations.css":1,"sites\/default\/themes\/bmjj\/css\/components\/nice-menus.css":1,"sites\/default\/themes\/bmjj\/css\/components\/menus.css.less":1,"sites\/default\/themes\/bmjj\/css\/components\/chosen.css":1,"sites\/default\/themes\/bmjj\/css\/theme\/theme.css.less":1,"sites\/default\/themes\/bmjj\/css\/theme\/colors.css.less":1,"sites\/default\/themes\/bmjj\/css\/theme\/breakpoints.css.less":1,"sites\/default\/themes\/bmjj\/css\/theme\/ie.css":1,"sites\/all\/modules\/highwire\/highwire\/css\/highwire-forms.css":1},"js":{"sites\/all\/libraries\/enquire.js\/enquire.min.js":1,"sites\/all\/themes\/highwire\/axon\/js\/theme-scripts.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_foxycart\/highwire_foxycart.js":1,"sites\/default\/modules\/jnl_template_bmjj_styles\/js\/svg4everybody\/dist\/svg4everybody.min.js":1,"sites\/default\/modules\/jnl_template_bmjj_styles\/js\/jnl_template_bmjj_svg.js":1,"sites\/default\/modules\/jnl_template_bmjj\/js\/bmj_footer_resource_centre.js":1,"sites\/default\/modules\/jnl_template_bmjj\/js\/bmj_footer_contactus.js":1,"sites\/default\/modules\/jnl_template_bmjj_styles\/js\/jnl_template_bmjj_question_toggle.js":1,"sites\/all\/libraries\/modernizr\/modernizr.min.js":1,"sites\/all\/modules\/contrib\/jquery_update\/replace\/jquery\/1.8\/jquery.min.js":1,"misc\/jquery-extend-3.4.0.js":1,"misc\/jquery.once.js":1,"https:\/\/securepubads.g.doubleclick.net\/tag\/js\/gpt.js":1,"misc\/drupal.js":1,"sites\/all\/modules\/contrib\/jquery_update\/replace\/ui\/external\/jquery.cookie.js":1,"sites\/all\/modules\/contrib\/jquery_update\/replace\/misc\/jquery.form.min.js":1,"misc\/ajax.js":1,"sites\/all\/modules\/contrib\/jquery_update\/js\/jquery_update.js":1,"sites\/all\/modules\/highwire\/highwire\/js\/highwire.equal-heights.js":1,"sites\/all\/modules\/highwire\/highwire\/js\/highwire.panels-ajax-tab.js":1,"sites\/all\/libraries\/colorbox\/jquery.colorbox-min.js":1,"sites\/all\/modules\/contrib\/colorbox\/js\/colorbox.js":1,"sites\/all\/modules\/contrib\/colorbox\/styles\/default\/colorbox_style.js":1,"sites\/all\/modules\/contrib\/foxycart\/foxycart.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_log\/highwire_log.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_nps_survey\/js\/nps_survey.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_user\/js\/highwire_user_meta.js":1,"sites\/all\/modules\/contrib\/views\/js\/base.js":1,"misc\/progress.js":1,"sites\/all\/modules\/contrib\/views\/js\/ajax_view.js":1,"sites\/all\/modules\/highwire\/highwire\/js\/highwire.article-citation-access.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_responsive\/plugins\/styles\/highwire_responsive_toggle\/highwire_responsive_toggle.js":1,"sites\/all\/modules\/highwire\/highwire\/js\/highwire.gtranslate.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_datalayer\/js\/highwire_datalayer.js":1,"sites\/default\/modules\/contrib\/menu_attach_block\/menu_attach_block.js":1,"sites\/default\/themes\/bmjj\/js\/theme-scripts.js":1,"sites\/default\/themes\/bmjj\/js\/svg4everybody.js":1,"sites\/default\/themes\/bmjj\/js\/jquery.cookieBar.js":1,"sites\/default\/themes\/bmjj\/js\/uuid.js":1,"sites\/all\/modules\/highwire\/highwire\/highwire_responsive\/js\/highwire-mediaqueries.js":1,"\/\/cdn.foxycart.com\/bmjpg.ecommerce.highwire.org\/loader.js":1}},"colorbox":{"opacity":"0.85","current":"{current} of {total}","previous":"\u00ab Prev","next":"Next \u00bb","close":"Close","maxWidth":"98%","maxHeight":"98%","fixed":true,"mobiledetect":true,"mobiledevicewidth":"480px"},"user_uid":0,"customer_email":"","cartstack_siteid":"","foxycart_subdomain":"bmjpg.ecommerce.highwire.org","foxycart_always_show_cart_link":1,"hw_fc_cookie_domain":".bmj.com","jcarousel":{"ajaxPath":"\/jcarousel\/ajax\/views"},"views":{"ajax_path":"\/views\/ajax","ajaxViews":{"views_dom_id:b662348143ffc8445f0a41e98f726abf":{"view_name":"bmjj_recent_articles_pap_only","view_display_id":"block","view_args":"","view_path":"front","view_base_path":null,"view_dom_id":"b662348143ffc8445f0a41e98f726abf","pager_element":0}}},"urlIsAjaxTrusted":{"\/views\/ajax":true,"\/":true},"highwire":{"ac":{"gutjnl;73\/11\/1893":{"access":{"full":true},"pisa_id":"gutjnl;73\/11\/1893","apath":"","jcode":"gutjnl"},"gutjnl;73\/4\/691":{"access":{"full":true},"pisa_id":"gutjnl;73\/4\/691","apath":"","jcode":"gutjnl"},"gutjnl;73\/2\/361":{"access":{"full":true},"pisa_id":"gutjnl;73\/2\/361","apath":"","jcode":"gutjnl"},"gutjnl;gutjnl-2024-332837v2":{"access":{"full":true},"pisa_id":"gutjnl;gutjnl-2024-332837v2","apath":"","jcode":"gutjnl"},"gutjnl;gutjnl-2024-332902v2":{"access":{"full":true},"pisa_id":"gutjnl;gutjnl-2024-332902v2","apath":"","jcode":"gutjnl"}},"dataLayer":"{\u0022page\u0022:{\u0022hwTitle\u0022:\u0022Homepage\u0022,\u0022hwUrl\u0022:\u0022https:\\\/\\\/gut.bmj.com\\\/\u0022,\u0022hwPath\u0022:\u0022\\\/\u0022,\u0022hwType\u0022:\u0022home page\u0022},\u0022user\u0022:{\u0022hwMemberID\u0022:\u0022\u0022,\u0022hwLoggedIntoInstitutionID\u0022:\u0022\u0022,\u0022hwLoggedIntoInstitution\u0022:\u0022\u0022,\u0022hwAccessUsageTerms\u0022:\u0022guest\u0022,\u0022hwRegisteredUser\u0022:\u0022no\u0022,\u0022mail\u0022:\u0022e3b0c44298fc1c149afbf4c8996fb92427ae41e4649b934ca495991b7852b855\u0022}}"},"highwireResponsive":{"enquire_enabled":1,"breakpoints_configured":1,"breakpoints":{"narrow":"all and (min-width: 768px) and (min-device-width: 768px), (max-device-width: 800px) and (min-width: 768px) and (orientation:landscape)","normal":"all and (min-width: 1024px) and (min-device-width: 1024px), all (max-width: 1220px) and (max-device-width: 1220px) and (orientation:landscape)","wide":"all and (min-width: 1220px)"}}}); //--><!]]> </script> <!--[if lt IE 10]><script src="https://gut.bmj.com/sites/all/themes/highwire/axon/js/media.match.min.js" type="text/javascript"></script><![endif]--> <!--[if lt IE 9]><link rel="stylesheet" type="text/css" href="/sites/default/themes/bmjj/css/theme/ie-7-8.css" /><![endif]--> <script> let cookies = parseCookies(); let bmj_uuid = cookies.bmj_uuid; let bmj_ppid = cookies.bmj_ppid; window.dataLayer = window.dataLayer || []; const anonMailId = 'e3b0c44298fc1c149afbf4c8996fb92427ae41e4649b934ca495991b7852b855'; function checkUserLoginStatus(dataLayer) { const userMail = dataLayer.find((item) => item.user)?.user?.mail; if (!userMail) { return false; } return userMail !== anonMailId; } let nonAnonMailId = ((dataLayer.find(item => item.user)?.user)?.mail) === anonMailId ? null : (dataLayer.find(item => item.user)?.user)?.mail; let userId = ((dataLayer.find(item => item.user)?.user)?.['data-ics']) ?? ((dataLayer.find(item => item.user)?.user)?.mail && nonAnonMailId) ?? bmj_ppid ?? bmj_uuid; document.cookie = 'bmj_ppid=' + userId + '; domain=.bmj.com; path=/; max-age=31622400; SameSite=None; Secure'; googletag.cmd.push(function() { googletag.pubads().setPublisherProvidedId(userId); googletag.pubads().setTargeting("islogged", checkUserLoginStatus(dataLayer) ? "true" : "false"); googletag.enableServices(); }); window.dataLayer.push({ 'bmj_uuid': bmj_uuid }); </script> </head> <body class="html front not-logged-in no-sidebars"> <!-- Google Tag Manager --> <noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-KMTW8J" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <script type="text/javascript">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0];var j=d.createElement(s);var dl=l!='dataLayer'?'&l='+l:'';j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;j.type='text/javascript';j.async=true;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-KMTW8J');</script> <!-- End Google Tag Manager --> <div id="skip-link"> <a href="#main-content" class="element-invisible element-focusable">Skip to main content</a> </div> <div class="page" id="page"> <section class="container-fluid content-header"> <header role="banner" class="section section-header row"> <div class="zone zone-superheader"> <div class="region region-superheader"> <div class="region-inner region-superheader-inner"> <div class="region region-superheader"> <div id="block-panels-mini-jnl-template-bmjj-uid-strng" class="block block-panels-mini" class="block block-panels-mini"> <div class="content"> <div class="panel-display panel-1col clearfix" id="mini-panel-jnl_template_bmjj_uid_strng"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-dfp-pane" > <div class="pane-content"> <div id="dfp-ad-top-wrapper" class="dfp-tag-wrapper"> <div id="dfp-ad-top" class="dfp-tag-wrapper"> <script type="text/javascript"> googletag.cmd.push(function() { googletag.display("dfp-ad-top"); }); </script> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div><!-- /.region-superheader --> </div><!-- /.zone-super-header --> <div class="site-info mobile-hidden"> </div><!-- /.site-info --> <div class="zone zone-header row mobile-hidden"> <div class="region region-header"> <div class="region-inner region-header-inner"> </div> </div><!-- ./region-header --> </div><!-- /.zone-header --> </header> <!-- /.section-header --> <section class="row visible-sm visible-md visible-lg header header-platform mobile-hidden"> <div class="col-narrow-3 col-normal-3 col-large-3 logo-bmj"> <div class="l-inline"> <p class="logo-bmj-journals"><a href="http://journals.bmj.com/" title="BMJ Journals"><img src="/sites/default/themes/bmjj/img/logos/logo-bmj-journals.svg" title="BMJ Journals" alt="BMJ Journals"/></a></p> </div> </div> <div class="col-narrow-9 col-normal-9 col-large-9 no-right-padding"> <div class="region region-top"> <div class="region-inner"> <div class="region region-platmenu"> <div id="block-menu-menu-platform-menu" class="block block-menu" class="block block-menu"> <div class="content"> <ul class="menu"><li class="first leaf"><a href="/subscribe" data-hide-link-title="0" class="header-subscribe-link" data-icon-position="">Subscribe</a></li> <li class="leaf"><a href="/" id="menu-login" class="drop-menu active link-icon-right link-icon"><span class="title">Log In</span> <span class="icon icon-arrow-down"></span></a> <a href="# " class="menu-attach-block-drop-link external expand-on-click" data-block-id="panels_mini|challenge_opportunity_pane_dropdown" id="&lt;front&gt;-drop-link-728" data-icon-position="" data-hide-link-title="0">More</a><div class="menu-attach-block-wrapper"> <div id="block-panels-mini-challenge-opportunity-pane-dropdown" class="block block-panels-mini article-login bmjj-login" class="block block-panels-mini"> <div class="content"> <div class="panel-display panel-1col clearfix" id="mini-panel-challenge_opportunity_pane_dropdown"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-bmjj-society-logins society-logins" > <div class="pane-content"> <span class="ui-button ui-state-default ui-dialog-titlebar-close" title="close"></span><div class="shib-login-link"><a href="/login/shibboleth?subcode=bmjjournals&amp;env=prod&amp;uri=https%3A//gut.bmj.com/accallback/front" class="button society-login-link" data-icon-position="" data-hide-link-title="0">Log in via Institution</a></div><div class="openathens-login-link"><a href="https://openathens-sp.highwire.org/session/init?entityID=https%3A//idp.eduserv.org.uk/openathens&amp;hw-shib-return-uri=https%3A//gut.bmj.com/accallback/front&amp;subcode=bmjjournals" class="button society-login-link" data-icon-position="" data-hide-link-title="0">Log in via OpenAthens</a></div><a href="https://www.bsg.org.uk/login.html" class="button society-login-link" data-icon-position="" data-hide-link-title="0">Log in via BSG</a> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-highwire-opportunity-challenge" > <div class="pane-content"> <div class='opportunity-challenge-login'><h3>Log in using your username and password</h3><div class="drupal-login compact"><form action="/" method="post" id="highwire-user-login--2" accept-charset="UTF-8"><div><div id="edit-customtext--2" class="form-item form-item-label-before form-type-item"> <span class="customtext">For personal accounts OR managers of institutional accounts</span> </div> <div class="form-item form-item-label-invisible form-type-textfield form-item-name"> <label class="element-invisible" for="edit-name--2">Username <span class="form-required" title="This field is required.">*</span></label> <input placeholder="Username" type="text" id="edit-name--2" name="name" value="" size="30" maxlength="60" class="form-text required" /> </div> <div class="form-item form-item-label-invisible form-type-password form-item-pass"> <label class="element-invisible" for="edit-pass--2">Password <span class="form-required" title="This field is required.">*</span></label> <input placeholder="Password" type="password" id="edit-pass--2" name="pass" size="30" maxlength="128" class="form-text required" /> </div> <input type="hidden" name="form_build_id" value="form-AiWuH-WTqH8dii5PS-WHJhgKLxyrtT2QHZpopmDMx7w" /> <input type="hidden" name="form_id" value="highwire_user_login" /> <div class="bmjj-reset-password"><a href="/user/password" class="" data-icon-position="" data-hide-link-title="0">Forgot your log in details?</a><a href="/user/register?destination=front" class="" data-icon-position="" data-hide-link-title="0">Register a new account?</a></div><div class="form-actions form-wrapper" id="edit-actions--2"><input type="submit" id="edit-submit--2" name="op" value="Log in" class="form-submit" /></div><div class="reset-password"><a href="/user/password" class="" data-icon-position="" data-hide-link-title="0">Forgot</a> your user name or password?</div></div></form></div></div> </div> </div> </div> </div> </div> </div> </div> </div> </li> <li class="leaf"><a href="/cart" class="link-icon-right link-icon"><span class="title">Basket</span> <span class="icon icon-basket"></span></a></li> <li class="last leaf"><a href="/search" id="menu-search" class="drop-menu link-icon-right link-icon"><span class="title">Search</span> <span class="icon icon-search"></span></a> <a href="# " class="menu-attach-block-drop-link external expand-on-click" data-block-id="panels_mini|jnl_template_bmjj_search_box" id="search-drop-link-729" data-icon-position="" data-hide-link-title="0">More</a><div class="menu-attach-block-wrapper"> <div id="block-panels-mini-jnl-template-bmjj-search-box" class="block block-panels-mini" class="block block-panels-mini"> <div class="content"> <div class="panel-display one-layout " id="mini-panel-jnl_template_bmjj_search_box-1"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-highwire-seach-quicksearch block-search pull-left" > <div class="pane-content"> <form class="highwire-quicksearch button-style-mini button-style-mini" action="/" method="post" id="highwire-search-quicksearch-form-1" accept-charset="UTF-8"><div><div class="form-item form-item-label-invisible form-type-textfield form-item-keywords"> <label class="element-invisible" for="search_rightsidebar_keywords_151606774">Search for this keyword </label> <input placeholder="search" type="text" id="search_rightsidebar_keywords_151606774" name="keywords" value="" size="60" maxlength="128" class="form-text" /> </div> <input data-icon-only="1" data-font-icon="icon-search" data-icon-position="after" type="submit" id="search_rightsidebar_submit_221424870" name="op" value="Search" class="form-submit" /><input type="hidden" name="form_build_id" value="form-XCp2oKaVP4pFepAsxUUfNevirLomxNqHzG6KItEHciI" /> <input type="hidden" name="form_id" value="highwire_search_quicksearch_form_1" /> </div></form> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-custom pane-2 pull-right advanced-search-link" > <div class="pane-content"> <a href="/search">Advanced search</a> </div> </div> </div> </div> </div> </div> </div> </div> </li> </ul> </div> </div> </div> </div> </div><!-- /.region-top --> </div> </section> <div class="row header header-journal"> <div class="col-mobile-7 col-narrow-2 col-normal-4 logo-journal"> <h1 class="element-invisible">Gut journal home page</h1> <a href="/"><img src="https://resources.bmj.com/repository/journals-network-project/images/journal-logos/logo-gut.svg" alt="Gut" id="logo-img"></a> </div> <div class="col-mobile-5 col-narrow-10 col-normal-8 no-right-padding nav-journal"> <div class="region region-journmenu"> <div id="block-system-main-menu" class="block block-system mobile-hidden block-menu" class="block block-system mobile-hidden block-menu"> <div class="content"> <ul class="menu"><li class="first leaf"><a href="http://gut.bmj.com/pages/education-in-gastroenterology" class="" data-icon-position="" data-hide-link-title="0">CME/CPD</a></li> <li class="leaf"><a href="/content/early/recent" class="" data-icon-position="" data-hide-link-title="0">Latest content</a></li> <li class="leaf"><a href="/content/current" class="" data-icon-position="" data-hide-link-title="0">Current issue</a></li> <li class="leaf"><a href="/content/by/year" class="" data-icon-position="" data-hide-link-title="0">Archive</a></li> <li class="leaf"><a href="http://gut.bmj.com/pages/authors/" class="" data-icon-position="" data-hide-link-title="0">Authors</a></li> <li class="last leaf"><a href="http://gut.bmj.com/pages/about/" class="" data-icon-position="" data-hide-link-title="0">About</a></li> </ul> </div> </div> <div id="block-panels-mini-mobile-slide-out-menu" class="block block-panels-mini mobile-only" class="block block-panels-mini mobile-only"> <div class="content"> <div class="panel-display panel-1col clearfix" id="mini-panel-mobile_slide_out_menu"> <div class="panel-panel panel-col"> <div><div id="" class="highwire-responsive-toggle-group"><div class="panel-pane pane-panels-mini pane-jnl-template-bmjj-search-box" > <h2 class="pane-title"><span class="icon-search"></span></h2> <div class="pane-content"> <div class="panel-display one-layout " id="mini-panel-jnl_template_bmjj_search_box"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-highwire-seach-quicksearch block-search pull-left" > <div class="pane-content"> <form class="highwire-quicksearch button-style-mini button-style-mini" action="/" method="post" id="highwire-search-quicksearch-form-0" accept-charset="UTF-8"><div><div class="form-item form-item-label-invisible form-type-textfield form-item-keywords"> <label class="element-invisible" for="search_rightsidebar_keywords_1493819454">Search for this keyword </label> <input placeholder="search" type="text" id="search_rightsidebar_keywords_1493819454" name="keywords" value="" size="60" maxlength="128" class="form-text" /> </div> <input data-icon-only="1" data-font-icon="icon-search" data-icon-position="after" type="submit" id="search_rightsidebar_submit_908554363" name="op" value="Search" class="form-submit" /><input type="hidden" name="form_build_id" value="form-AQ60oUVnIS3deWYzbiOum2EWBDovqUMed4TdTtV43kc" /> <input type="hidden" name="form_id" value="highwire_search_quicksearch_form_0" /> </div></form> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-custom pane-1 pull-right advanced-search-link" > <div class="pane-content"> <a href="/search">Advanced search</a> </div> </div> </div> </div> </div> </div> </div> <div class="panel-pane pane-block pane-menu-menu-mobile-slideout-menu pane-menu" > <h2 class="pane-title"><span class="icon-menu"></span></h2> <div class="pane-content"> <ul class="menu"><li class="first leaf"><a href="/" class="menu-close active link-icon-only link-icon"><span class="icon icon-close"></span> <span class="title element-invisible">Close</span></a> <a href="# " class="menu-attach-block-drop-link external expand-on-click" data-block-id="panels_mini|mobile_slide_out_autobot_menu" id="&lt;front&gt;-drop-link-781" data-icon-position="" data-hide-link-title="0">More</a><div class="menu-attach-block-wrapper"> <div id="block-panels-mini-mobile-slide-out-autobot-menu" class="block block-panels-mini" class="block block-panels-mini"> <div class="content"> <div class="panel-display one-layout " id="mini-panel-mobile_slide_out_autobot_menu"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-menu-tree pane-main-menu" > <h2 class="pane-title">Main menu</h2> <div class="pane-content"> <div class="menu-block-wrapper menu-block-ctools-main-menu-1 menu-name-main-menu parent-mlid-main-menu:0 menu-level-1"> <ul class="menu"><li class="first leaf menu-mlid-15035"><a href="http://gut.bmj.com/pages/education-in-gastroenterology" class="" data-icon-position="" data-hide-link-title="0">CME/CPD</a></li> <li class="leaf menu-mlid-15036"><a href="/content/early/recent" class="" data-icon-position="" data-hide-link-title="0">Latest content</a></li> <li class="leaf menu-mlid-15037"><a href="/content/current" class="" data-icon-position="" data-hide-link-title="0">Current issue</a></li> <li class="leaf menu-mlid-15038"><a href="/content/by/year" class="" data-icon-position="" data-hide-link-title="0">Archive</a></li> <li class="leaf menu-mlid-15039"><a href="http://gut.bmj.com/pages/authors/" class="" data-icon-position="" data-hide-link-title="0">Authors</a></li> <li class="last leaf menu-mlid-15040"><a href="http://gut.bmj.com/pages/about/" class="" data-icon-position="" data-hide-link-title="0">About</a></li> </ul></div> </div> </div> </div> </div> </div> </div> </div> </div> </li> <li class="leaf"><a href="/subscribe" data-hide-link-title="0" class="callout-link" data-icon-position="">Subscribe</a></li> <li class="leaf"><a href="/" class="mobile-drop-down callout-link active link-icon-right link-icon"><span class="title">Log in</span> <span class="icon icon-plus"></span></a> <a href="# " class="menu-attach-block-drop-link external expand-on-click" data-block-id="panels_mini|jnl_template_bmjj_login" id="&lt;front&gt;-drop-link-780" data-icon-position="" data-hide-link-title="0">More</a><div class="menu-attach-block-wrapper"> <div id="block-panels-mini-jnl-template-bmjj-login" class="block block-panels-mini" class="block block-panels-mini"> <div class="content"> <div class="panel-display panel-1col clearfix" id="mini-panel-jnl_template_bmjj_login"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-bmjj-society-logins society-logins opportunity-challenge-login" > <div class="pane-content"> <span class="ui-button ui-state-default ui-dialog-titlebar-close" title="close"></span><div class="shib-login-link"><a href="/login/shibboleth?subcode=bmjjournals&amp;env=prod&amp;uri=https%3A//gut.bmj.com/accallback/front" class="button society-login-link" data-icon-position="" data-hide-link-title="0">Log in via Institution</a></div><div class="openathens-login-link"><a href="https://openathens-sp.highwire.org/session/init?entityID=https%3A//idp.eduserv.org.uk/openathens&amp;hw-shib-return-uri=https%3A//gut.bmj.com/accallback/front&amp;subcode=bmjjournals" class="button society-login-link" data-icon-position="" data-hide-link-title="0">Log in via OpenAthens</a></div><a href="https://www.bsg.org.uk/login.html" class="button society-login-link" data-icon-position="" data-hide-link-title="0">Log in via BSG</a> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-highwire-opportunity-challenge" > <div class="pane-content"> <div class='opportunity-challenge-login'><h3>Log in using your username and password</h3><div class="drupal-login compact"><form action="/" method="post" id="highwire-user-login" accept-charset="UTF-8"><div><div id="edit-customtext" class="form-item form-item-label-before form-type-item"> <span class="customtext">For personal accounts OR managers of institutional accounts</span> </div> <div class="form-item form-item-label-invisible form-type-textfield form-item-name"> <label class="element-invisible" for="edit-name">Username <span class="form-required" title="This field is required.">*</span></label> <input placeholder="Username" type="text" id="edit-name" name="name" value="" size="30" maxlength="60" class="form-text required" /> </div> <div class="form-item form-item-label-invisible form-type-password form-item-pass"> <label class="element-invisible" for="edit-pass">Password <span class="form-required" title="This field is required.">*</span></label> <input placeholder="Password" type="password" id="edit-pass" name="pass" size="30" maxlength="128" class="form-text required" /> </div> <input type="hidden" name="form_build_id" value="form-2GqWfQ2c6tBSOuYjb4f5Opky_uBhfwG0ikyGaizLizc" /> <input type="hidden" name="form_id" value="highwire_user_login" /> <div class="bmjj-reset-password"><a href="/user/password" class="" data-icon-position="" data-hide-link-title="0">Forgot your log in details?</a><a href="/user/register?destination=front" class="" data-icon-position="" data-hide-link-title="0">Register a new account?</a></div><div class="form-actions form-wrapper" id="edit-actions"><input type="submit" id="edit-submit" name="op" value="Log in" class="form-submit" /></div><div class="reset-password"><a href="/user/password" class="" data-icon-position="" data-hide-link-title="0">Forgot</a> your user name or password?</div></div></form></div></div> </div> </div> </div> </div> </div> </div> </div> </div> </li> <li class="last leaf"><a href="http://journals.bmj.com/" data-hide-link-title="0" class="bmj-link" data-icon-position="">BMJ Journals</a></li> </ul> </div> </div> </div></div> </div> </div> </div> </div> </div> </div><!-- /.region-top --> </div> </section> <section role="main" class="section section-content container-fluid"> <div class="crumb-navigation"> <div class="row"> <div class="col-mobile-12 col-narrow-9 col-normal-9 col-wide-10 breadcrumbs"> </div> <div class="mobile-hidden col-narrow-3 col-normal-3 col-wide-2 email-alerts"> <span> <a href="https://myaccount.bmj.com/myaccount/signup.html?regService=etoc-alerts&amp;corpusCode=gutjnl&amp;fwdUrl=https://gut.bmj.com/" class="email-alerts-label"><i class="icon icon-article-alerts"></i>Email alerts</a> </span> </div> </div> </div> <div class="container"> <div class="zone zone-content row"> <div class="region region-content col-narrow-12"> <div class="region-inner region-content-inner"> <a id="main-content"></a> <div class="region region-content"> <div id="block-system-main" class="block block-system" class="block block-system"> <div class="content"> <div class="panel-display home-layout " id="front-page-container"> <div class="panel-row-wrapper row"> <div class="top-left-wrapper col-narrow-8"> <div class="panel-panel panel-region-top-left"> <div class="inside"><div class="panel-pane pane-snippet" > <div class="pane-content"> <div class="snippet jnl-template-bmjj-about-journal-snippet" id="jnl-template-bmjj-about-journal-snippet"> <div class="snippet-content"> Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas including articles by leading authorities, reports on the latest treatments for diseases, reviews and commentaries. Gut is an official journal of the <a href="http://www.bsg.org.uk/">British Society of Gastroenterology</a>, subscribers to Gut also receive Frontline Gastroenterology . </div> </div> </div> </div> </div> </div> </div> <div class="top-right-wrapper col-narrow-4"> <div class="panel-panel panel-region-top-right"> <div class="inside"></div> </div> </div> </div> <!-- /.panel-row-wrapper --> <div class="panel-row-wrapper row row-mid-double"> <div class="middle-left-wrapper col-narrow-6"> <div class="panel-panel panel-region-middle-left"> <div class="inside"><div class="panel-pane pane-views pane-bmjj-recent-articles-pap-only clear clearfix" > <h2 class="pane-title uppercase with-icon-class"><span class="icon-background-circle"><svg class="icon-article-text svg-icon" aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-article-text"></use></svg></span><span class="title-text">LATEST ARTICLES</span></h2> <div class="pane-content"> <div class="view view-bmjj-recent-articles-pap-only view-id-bmjj_recent_articles_pap_only view-display-id-block view-dom-id-b662348143ffc8445f0a41e98f726abf"> <div class="view-content"> <div class="highwire-list-wrapper highwire-article-citation-list"><div class="highwire-list"><ul><li class="first odd"><div class="highwire-article-citation highwire-citation-type-highwire-article node265652" data-node-nid="265652" id="node-265652--21754386590" data-pisa="gutjnl;gutjnl-2024-332901v1" data-pisa-master="gutjnl;gutjnl-2024-332901" data-apath="/gutjnl/early/2024/11/22/gutjnl-2024-332901.atom"><div class="highwire-cite highwire-cite-highwire-article highwire-citation- clearfix"> <div class="highwire-cite-title">Spatial dissection of tumour microenvironments in gastric cancers reveals the immunosuppressive crosstalk between <em>CCL2+</em> fibroblasts and <em>STAT3</em>-activated macrophages</div> </div> </div></li><li class="even"><div class="highwire-article-citation highwire-citation-type-highwire-article node265653" data-node-nid="265653" id="node-265653--2447354500" data-pisa="gutjnl;gutjnl-2024-332619v2" data-pisa-master="gutjnl;gutjnl-2024-332619" data-apath="/gutjnl/early/2024/11/22/gutjnl-2024-332619.atom"><div class="highwire-cite highwire-cite-highwire-article highwire-citation- clearfix"> <div class="highwire-cite-title">Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates</div> </div> </div></li><li class="odd"><div class="highwire-article-citation highwire-citation-type-highwire-article node265623" data-node-nid="265623" id="node-265623--2544484121" data-pisa="gutjnl;gutjnl-2024-332594v1" data-pisa-master="gutjnl;gutjnl-2024-332594" data-apath="/gutjnl/early/2024/11/20/gutjnl-2024-332594.atom"><div class="highwire-cite highwire-cite-highwire-article highwire-citation- clearfix"> <div class="highwire-cite-title">Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression</div> </div> </div></li><li class="even"><div class="highwire-article-citation highwire-citation-type-highwire-article node265574" data-node-nid="265574" id="node-265574--2958235570" data-pisa="gutjnl;gutjnl-2024-333364v1" data-pisa-master="gutjnl;gutjnl-2024-333364" data-apath="/gutjnl/early/2024/11/18/gutjnl-2024-333364.atom"><div class="highwire-cite highwire-cite-highwire-article highwire-citation- clearfix"> <div class="highwire-cite-title">Liquid biopsy to identify Barrett鈥檚 oesophagus, dysplasia and oesophageal adenocarcinoma: the <em>EMERALD</em> multicentre study</div> </div> </div></li><li class="last odd"><div class="highwire-article-citation highwire-citation-type-highwire-article node265575" data-node-nid="265575" id="node-265575--21939572865" data-pisa="gutjnl;gutjnl-2024-333598v1" data-pisa-master="gutjnl;gutjnl-2024-333598" data-apath="/gutjnl/early/2024/11/18/gutjnl-2024-333598.atom"><div class="highwire-cite highwire-cite-highwire-article highwire-citation- clearfix"> <div class="highwire-cite-title">Faecal phageome transplantation alleviates intermittent intestinal inflammation in IBD and the timing of transplantation matters: a preclinical proof-of-concept study in mice</div> </div> </div></li></ul></div></div> </div> </div> </div> </div> </div> </div> </div> <div class="middle-right-wrapper col-narrow-6"> <div class="panel-panel panel-region-middle-right"> <div class="inside"><div class="panel-pane pane-highwire-reports-feed" > <h2 class="pane-title uppercase with-icon-class"><span class="icon-background-circle"><svg class="icon-star svg-icon" aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-star"></use></svg></span><span class="title-text">POPULAR ARTICLES</span></h2> <div class="pane-content"> <div class="highwire-list-wrapper highwire-article-citation-list"><div class="highwire-list"><ul class="highwire-feed-reports"><li class="first odd"><div class="highwire-article-citation highwire-citation-type-highwire-article node264638" data-node-nid="264638" id="node-264638--21849440221" data-pisa="gutjnl;73/11/1893" data-pisa-master="gutjnl;gutjnl-2024-333378" data-apath="/gutjnl/73/11/1893.atom"><cite class='highwire-cite highwire-citation-bmjj-home'> <div class='highwire-cite-category'>Recent advances in basic science</div> <div class='highwire-cite-title'><a href="/content/73/11/1893" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">What defines a healthy gut microbiome?</span></a><span class="date">(25 September, 2024)</span> <div class="highwire-cite-access"><span class="highwire-citation-access"><svg class="icon icon-open-access bmjj-open-access bmjj-access-tag"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-openaccess"></use><svg></svg></svg></span></div> </div> </cite> </div></li><li class="even"><div class="highwire-article-citation highwire-citation-type-highwire-article node259804" data-node-nid="259804" id="node-259804--21123778430" data-pisa="gutjnl;73/4/691" data-pisa-master="gutjnl;gutjnl-2023-330595" data-apath="/gutjnl/73/4/691.atom"><cite class='highwire-cite highwire-citation-bmjj-home'> <div class='highwire-cite-category'>Recent advances in clinical practice</div> <div class='highwire-cite-title'><a href="/content/73/4/691" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">MASLD: a systemic metabolic disorder with cardiovascular and malignant complications</span></a><span class="date">(16 January, 2024)</span><img src="/sites/default/modules/jnl_template_bmjj/plugins/content_types/images/editors-choice.svg" alt="Editor's Choice" class="bmjj-access-tag editors-choice bmjj-editors-choice"> <div class="highwire-cite-access"><span class="highwire-citation-access highwire-citation-access-check" data-pisa-id="gutjnl;gutjnl-2023-330595" data-atom-uri="/gutjnl/73/4/691.atom" data-request-view="full"><span class="highwire-access-icon highwire-access-icon-user-access user-access bmjj-free bmjj-free-access bmjj-access-tag" title="You have access">Free</span></span></div> </div> </cite> </div></li><li class="odd"><div class="highwire-article-citation highwire-citation-type-highwire-article node258738" data-node-nid="258738" id="node-258738--2895915619" data-pisa="gutjnl;73/2/361" data-pisa-master="gutjnl;gutjnl-2023-330616" data-apath="/gutjnl/73/2/361.atom"><cite class='highwire-cite highwire-citation-bmjj-home'> <div class='highwire-cite-category'>Recent advances in clinical practice</div> <div class='highwire-cite-title'><a href="/content/73/2/361" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">Updates to the modern diagnosis of GERD: Lyon consensus 2.0</span></a><span class="date">(21 September, 2023)</span> <div class="highwire-cite-access"><span class="highwire-citation-access"><svg class="icon icon-open-access bmjj-open-access bmjj-access-tag"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-openaccess"></use><svg></svg></svg></span></div> </div> </cite> </div></li><li class="even"><div class="highwire-article-citation highwire-citation-type-highwire-article node265061" data-node-nid="265061" id="node-265061--246670689" data-pisa="gutjnl;gutjnl-2024-332837v2" data-pisa-master="gutjnl;gutjnl-2024-332837" data-apath="/gutjnl/early/2024/10/14/gutjnl-2024-332837.atom"><cite class='highwire-cite highwire-citation-bmjj-home'> <div class='highwire-cite-category'>Hepatology</div> <div class='highwire-cite-title'><a href="/content/early/2024/10/14/gutjnl-2024-332837" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma</span></a><span class="date">(30 September, 2024)</span> <div class="highwire-cite-access"><span class="highwire-citation-access"><svg class="icon icon-open-access bmjj-open-access bmjj-access-tag"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-openaccess"></use><svg></svg></svg></span></div> </div> </cite> </div></li><li class="last odd"><div class="highwire-article-citation highwire-citation-type-highwire-article node265063" data-node-nid="265063" id="node-265063--21663225439" data-pisa="gutjnl;gutjnl-2024-332902v2" data-pisa-master="gutjnl;gutjnl-2024-332902" data-apath="/gutjnl/early/2024/10/14/gutjnl-2024-332902.atom"><cite class='highwire-cite highwire-citation-bmjj-home'> <div class='highwire-cite-category'>Hepatology</div> <div class='highwire-cite-title'><a href="/content/early/2024/10/14/gutjnl-2024-332902" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">Nuclear translocation of plasma membrane protein ADCY7 potentiates T cell-mediated antitumour immunity in HCC</span></a><span class="date">(30 September, 2024)</span> <div class="highwire-cite-access"><span class="highwire-citation-access"><svg class="icon icon-open-access bmjj-open-access bmjj-access-tag"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-openaccess"></use><svg></svg></svg></span></div> </div> </cite> </div></li></ul></div></div> </div> </div> </div> </div> </div> </div> <!-- /.panel-row-wrapper --> <div class="panel-row-wrapper panel-row-last row row-mid-bottom"> <div class="bottom-wrapper col-narrow-12"> <div class="panel-panel panel-region-bottom"> <div class="inside"><div class="panel-pane pane-block pane-menu-menu-home-page-publish-menu pane-menu" > <h2 class="pane-title uppercase with-icon-class"><span class="icon-background-circle"><svg class="icon-publish svg-icon" aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-publish"></use></svg></span><span class="title-text">Publish in this Journal</span></h2> <div class="pane-content"> <ul class="menu"><li class="first leaf"><a href="http://gut.bmj.com/pages/authors/" class="" data-icon-position="" data-hide-link-title="0">Instructions for authors</a></li> <li class="leaf"><a href="http://authors.bmj.com/" class="" data-icon-position="" data-hide-link-title="0">Author toolbox</a></li> <li class="last leaf"><a href="http://mc.manuscriptcentral.com/gut" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Submit a paper</a></li> </ul> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-bmjj-related-journals" > <h2 class="pane-title uppercase with-icon-class"><span class="icon-background-circle"><svg class="icon-related svg-icon" aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-related"></use></svg></span><span class="title-text">Related Journals</span></h2> <div class="pane-content"> <div class="row related_journals_list"><div class="col-mobile-12 col-narrow-6 col-normal-6 col-wide-6"><div class="journal-cover"><img src="https://fg.bmj.com/widget/public/current-issue/cover.gif" alt="Frontline Gastroenterology" /></div><div class="journal-info"><p class="journal-title uppercase">Frontline Gastroenterology</p><p><a href="http://fg.bmj.com/content/current/">Current issue</a></p><p><a href="http://fg.bmj.com/">Visit this journal</a></p></div></div><div class="col-mobile-12 col-narrow-6 col-normal-6 col-wide-6"><div class="journal-cover"><img src="https://resources.bmj.com/repository/journals-network-project/images/journal-covers-static/jnl-cover-bog.gif" alt="BMJ Open Gastroenterology" /></div><div class="journal-info"><p class="journal-title uppercase">BMJ Open Gastroenterology</p><p><a href="http://bmjopengastro.bmj.com/content/current/">Current issue</a></p><p><a href="http://bmjopengastro.bmj.com/">Visit this journal</a></p></div></div></div> </div> </div> </div> </div> </div> </div> <!-- /.panel-row-wrapper --> </div> </div> </div> </div> </div> </div><!-- /.region-content --> </div><!-- /.zone-content --> </div><!-- /.container --> </section> <!-- /.section-content --> </div> <!-- /.page --> <footer role="contentinfo" class="section section-footer container-fluid" id="footer"> <section class="zone zone-footer row footer-journal-societies"> <div class="region region-footer col-narrow-12"> <div class="region-inner region-footer-inner"> <div class="region region-footersoc"> <div id="block-panels-mini-footer-society-images" class="block block-panels-mini" class="block block-panels-mini"> <div class="content"> <div class="panel-display panel-1col clearfix" id="mini-panel-footer_society_images"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-bmjj-societies-logos" > <div class="pane-content"> <ul><li><a href="http://www.bsg.org.uk/"><img src="https://resources.bmj.com/repository/journals-network-project/images/society-logos/society-logo-bsg.png" alt="British Society of Gastroenterology" /></a></li></ul> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div><!-- /.region-footer-first --> </section> <section role="contentinfo" class="section section-footer"> <div class="zone zone-footer footer-links"> <nav class="row"> <div class="region region-footerlinks1"> <div id="block-menu-block-1" class="block block-menu-block" class="block block-menu-block"> <div class="content"> <div class="menu-block-wrapper menu-block-1 menu-name-menu-footer-menu-1 parent-mlid-0 menu-level-1"> <ul class="menu"><li class="first expanded active menu-mlid-15041 col-mobile-12 col-narrow-3 col-normal-3 col-wide-3"><a href="/" class="active" data-icon-position="" data-hide-link-title="0">Content</a><ul class="menu"><li class="first leaf menu-mlid-15042"><a href="/content/early/recent" class="" data-icon-position="" data-hide-link-title="0">Latest</a></li> <li class="leaf menu-mlid-15043"><a href="/content/current" class="" data-icon-position="" data-hide-link-title="0">Current issue</a></li> <li class="leaf menu-mlid-15044"><a href="/content/by/year" class="" data-icon-position="" data-hide-link-title="0">Archive</a></li> <li class="leaf menu-mlid-15045"><a href="http://gut.bmj.com/pages/education-in-gastroenterology" class="" data-icon-position="" data-hide-link-title="0">Education in Gastroenterology</a></li> <li class="leaf menu-mlid-15046"><a href="http://gut.bmj.com/pages/browse-by-topic/" class="" data-icon-position="" data-hide-link-title="0">Browse by collection</a></li> <li class="leaf menu-mlid-15047"><a href="https://gut.bmj.com/pages/visual-abstracts" class="" data-icon-position="" data-hide-link-title="0">Visual Abstracts</a></li> <li class="leaf menu-mlid-15048"><a href="http://gut.bmj.com/pages/most-read-articles/" class="" data-icon-position="" data-hide-link-title="0">Most read articles</a></li> <li class="leaf menu-mlid-15049"><a href="http://gut.bmj.com/pages/top-cited-articles/" class="" data-icon-position="" data-hide-link-title="0">Top cited articles</a></li> <li class="last leaf menu-mlid-15050"><a href="http://gut.bmj.com/pages/eletters" class="" data-icon-position="" data-hide-link-title="0">Responses</a></li> </ul></li> <li class="expanded active menu-mlid-15051 col-mobile-12 col-narrow-3 col-normal-3 col-wide-3"><a href="/" class="active" data-icon-position="" data-hide-link-title="0">Journal</a><ul class="menu"><li class="first leaf menu-mlid-15052"><a href="http://gut.bmj.com/pages/about/" class="" data-icon-position="" data-hide-link-title="0">About</a></li> <li class="leaf menu-mlid-15053"><a href="http://gut.bmj.com/site/about/edboard.xhtml" class="" data-icon-position="" data-hide-link-title="0">Editorial board</a></li> <li class="leaf menu-mlid-15054"><a href="https://myaccount.bmj.com/myaccount/signup.html?regService=etoc-alerts&amp;corpusCode=gutjnl&amp;fwdUrl=https://gut.bmj.com/" class="" data-icon-position="" data-hide-link-title="0">Sign up for email alerts</a></li> <li class="leaf menu-mlid-15055"><a href="http://gut.bmj.com/pages/subscribe/" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Subscribe</a></li> <li class="last leaf menu-mlid-15056"><a href="http://gut.bmj.com/pages/thank-you-to-our-reviewers/" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Thank you to our reviewers</a></li> </ul></li> <li class="expanded active menu-mlid-15057 col-mobile-12 col-narrow-3 col-normal-3 col-wide-3"><a href="/" class="active" data-icon-position="" data-hide-link-title="0">Authors</a><ul class="menu"><li class="first leaf menu-mlid-15058"><a href="http://gut.bmj.com/pages/authors/" class="" data-icon-position="" data-hide-link-title="0">Instructions for authors</a></li> <li class="leaf menu-mlid-15059"><a href="http://mc.manuscriptcentral.com/gut" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Submit an article paper</a></li> <li class="leaf menu-mlid-15060"><a href="http://authors.bmj.com/policies/" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Editorial policies</a></li> <li class="leaf menu-mlid-15061"><a href="http://openaccess.bmj.com/" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Open Access at BMJ</a></li> <li class="last leaf menu-mlid-15062"><a href="http://authors.bmj.com/" target="_blank" class="" data-icon-position="" data-hide-link-title="0">BMJ Author Hub</a></li> </ul></li> <li class="last expanded active menu-mlid-15063 col-mobile-12 col-narrow-3 col-normal-3 col-wide-3"><a href="/" class="active" data-icon-position="" data-hide-link-title="0">Help</a><ul class="menu"><li class="first leaf menu-mlid-15064"><a href="http://gut.bmj.com/pages/contact-us/" class="" data-icon-position="" data-hide-link-title="0">Contact us</a></li> <li class="leaf menu-mlid-15065"><a href="http://journals.bmj.com/cgi/reprintform" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Reprints</a></li> <li class="leaf menu-mlid-15066"><a href="http://www.bmj.com/company/products-services/rights-and-licensing/permissions" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Permissions</a></li> <li class="leaf menu-mlid-15067"><a href="https://www.bmj.com/company/for-advertisers-and-sponsor/" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Advertising</a></li> <li class="last leaf menu-mlid-15068"><a href="http://myaccount.bmj.com/myaccount/customerservice/salesforce-form.html" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Feedback form</a></li> </ul></li> </ul></div> </div> </div> </div> </nav> <div class="row"> <nav class="col-mobile-12 col-narrow-3 col-normal-3 col-wide-3"> <div class="region region-footersocial"> <div id="block-panels-mini-social-icons" class="block block-panels-mini" class="block block-panels-mini"> <div class="content"> <div class="panel-display panel-1col clearfix" id="mini-panel-social_icons"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-bmjj-social-icons" > <div class="pane-content"> <ul class="menu"><li class="leaf"><a href="http://gut.bmj.com/pages/rss-feeds" class="link-icon-only link-icon"><span class="icon icon-rss"></span><span class="title element-invisible"> RSS</span></a></li><li class="leaf"><a href="http://twitter.com/Gut_BMJ" class="link-icon-only link-icon"><span class="icon icon-twitter"></span><span class="title element-invisible"> Twitter</span></a></li><li class="leaf"><a href="http://www.facebook.com/Gut.BMJ" class="link-icon-only link-icon"><span class="icon icon-facebook"></span><span class="title element-invisible"> Facebook</span></a></li><li class="leaf"><a href="http://blogs.bmj.com/gut" class="link-icon-only link-icon"><span class="icon icon-blog"></span><span class="title element-invisible"> Blog</span></a></li><li class="leaf"><a href="https://soundcloud.com/bmjpodcasts/sets/gut-podcast" class="link-icon-only link-icon"><span class="icon icon-soundcloud"></span><span class="title element-invisible"> Soundcloud</span></a></li><li class="leaf"><a href="https://www.youtube.com/@GastroenterologyatBMJ-z9e" class="link-icon-only link-icon"><span class="icon icon-youtube"></span><span class="title element-invisible"> YouTube</span></a></li></ul> </div> </div> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </section><!-- /.section-footer --> <section class="row footer-platform"> <div class="col-mobile-12 col-narrow-4 logoBMJ"> <a href="http://www.bmj.com/company"><svg class="logo-bmj-svg" aria-hidden="true"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#logo-bmj"></use><svg></svg></svg></a> </div> <div class="col-mobile-12 col-narrow-8 legal"> <div class="legal-inner"> <ul> <li><a href="http://www.bmj.com/company/legal-information/">Website Terms &amp; Conditions</a></li> <li><a href="http://www.bmj.com/company/your-privacy/">Privacy &amp; Cookies</a></li> <li><a href="http://www.bmj.com/company/contact-us/">Contact BMJ</a></li> </ul> <!-- CookiePro Cookies Settings button start --> <button id="ot-sdk-btn" class="ot-sdk-show-settings">Cookie Settings</button> <!-- CookiePro Cookies Settings button end --> <p><small><span class="online-issn issn">Online ISSN: 1468-3288</span><span class="print-issn issn">Print ISSN: 0017-5749</span></small><br /> <small>Copyright 漏 2024 BMJ Publishing Group Ltd &amp; British Society of Gastroenterology. All rights reserved.</small></p> </div> </div> </section> <div class="region region-absolute-bottom"> <div class="region-inner region-absolute-bottom-inner"> <div class="region region-absolute-bottom"> <div id="block-panels-mini-bottom-ad" class="block block-panels-mini text-center" class="block block-panels-mini text-center"> <div class="content"> <div class="panel-display one-layout " id="mini-panel-bottom_ad"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-dfp-pane" > <div class="pane-content"> <div id="dfp-ad-bottom-wrapper" class="dfp-tag-wrapper"> <div id="dfp-ad-bottom" class="dfp-tag-wrapper"> <script type="text/javascript"> googletag.cmd.push(function() { googletag.display("dfp-ad-bottom"); }); </script> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div><!-- /.region-absolute-bottom --> </footer><!-- /.section-footer --> <script type="text/javascript" src="/sites/default/files/advagg_js/js__YP0skVzPJ9dKCqcnBr_uNCQOmTtCs151ae6sjES8kuE__m5Ong1RMpDawRuee_CcynJS11qwEmd3rA4TYQhs8HP4__dGRtyN8GJBuhBvXCmXEhVK4mGQl3ZIewHeJUeSvfyQ0.js"></script> <script type="text/javascript" src="/sites/default/files/advagg_js/js__Jd5dsvNznZMdglFu8sSni1wCsUfzvQbApHPAZwt5TY4__65Mqa1DMRwcSvPxjJEn6BXgMm-ckF3oOvkUTG9HRADI__dGRtyN8GJBuhBvXCmXEhVK4mGQl3ZIewHeJUeSvfyQ0.js" defer="defer"></script> <script type="text/javascript" src="/sites/default/files/advagg_js/js__fUCEaCKUODF5P2WmzGzo1laxaEQ82Nl6oADDw5nONTE__bGuvhZW_EmWlwuA1fnxwF8mvZ1E1v3qbDTqQdQd0TS0__dGRtyN8GJBuhBvXCmXEhVK4mGQl3ZIewHeJUeSvfyQ0.js"></script> </body> </html>

Pages: 1 2 3 4 5 6 7 8 9 10