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Sino Biological, Inc. on LinkedIn: #cancerresearch #biotechnology #celltherapy #webinar

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Biswas Biswas, Field Application Scientist at Sino Biological, for a webinar to discover the pivotal role of GMP-grade cytokines like IL-2, IL-7, and IL-15 in optimizing cell-based therapies on Tuesday, November 19 at 11AM CT / 12PM ET.\n\nWhy attend?\n\n💡Gain insights into how GMP-grade cytokines enhance immune cell function and drive effective treatments.\n💡Learn strategies to ensure safety and consistency in clinical applications.\n💡Understand the regulatory standards surrounding GMP-grade cytokines.\n💡Discover how to leverage these cytokines to improve therapeutic outcomes for cancer and autoimmune disorders.\n\nRegister: https://ow.ly/MHWF50U2FwN\n\n #CancerResearch #Biotechnology #CellTherapy #Webinar","sharedContent":{"@type":"WebPage"},"author":{"name":"Sino Biological, 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</div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate"> <!----> 21,613 followers </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 2w <!----> </time> <!----> </span> </div> <!----> </div> </div> <div class="ellipsis-menu absolute right-0 top-0 main-feed-activity-card__ellipsis-menu !top-auto !relative !mr-1" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/671xosfpvk4c0kqtyl87hashi"></icon> </button> <ul 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data-tracking-control-name="public_post-text" data-tracking-will-navigate>Oxford Global</a> and <a class="link" href="https://www.linkedin.com/in/ritwika-biswas-80780799?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Ritwika Biswas</a> Biswas, Field Application Scientist at Sino Biological, for a webinar to discover the pivotal role of GMP-grade cytokines like IL-2, IL-7, and IL-15 in optimizing cell-based therapies on Tuesday, November 19 at 11AM CT / 12PM ET. Why attend? 💡Gain insights into how GMP-grade cytokines enhance immune cell function and drive effective treatments. 💡Learn strategies to ensure safety and consistency in clinical applications. 💡Understand the regulatory standards surrounding GMP-grade cytokines. 💡Discover how to leverage these cytokines to improve therapeutic outcomes for cancer and autoimmune disorders. 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Stop by Poster #206 today and meet <a class="link" href="https://www.linkedin.com/in/renzo-adilardi?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Renzo Adilardi, PhD</a>, Scientist, R&amp;D, <a class="link" href="https://www.linkedin.com/company/advanced-cell-diagnostics?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Advanced Cell Diagnostics (ACD)</a> and learn more about how we're <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fadvancingspatialbiology&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#AdvancingSpatialBiology</a> to <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fseemorein2024&amp;trk=public_post-text" 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The global microRNA market, valued at USD 215.4 million in 2019, is witnessing rapid advancements, with a projected CAGR of 13.4% from 2020 to 2027. This growth is driven by the increasing application of microRNAs in disease diagnostics, therapeutic development, and biomarker discovery. By 2027, the market is expected to reach USD 613.2 million, reflecting the growing demand for precision medicine and the increasing focus on molecular research. The market is expanding due to innovations in RNA-based therapies, advancements in sequencing technologies, and the rising prevalence of chronic diseases such as cancer, cardiovascular conditions, and neurological disorders. These factors are contributing to the flourishing demand for microRNA-based solutions. Discover more insights with the free sample PDF here: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2Fg2D9ptSZ&amp;urlhash=vJI4&amp;trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/g2D9ptSZ</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmicrorna&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#microrna</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fgenomics&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#genomics</a> <a class="link" 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active:bg-color-background-container-tint focus:bg-color-background-container-tint hover:bg-color-background-container-tint outline-offset-[-2px]"> <!----> <icon class="ellipsis-menu__item-icon text-color-text h-[24px] w-[24px] mr-1" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/iq0x9q37wj214o129ai1yjut"> </icon> Report this post </a> <!----> </li> <!----> </ul> <!----> </div> </div> </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">🔬 Could enhancing glucose uptake in CAR-T therapies make them more potent? A recent study published in <a class="link" href="https://uk.linkedin.com/company/natureportfolio.?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Nature Portfolio</a> has demonstrated that overexpression of the glucose transporter, GLUT1, in CAR-T cells boosts their metabolism and improves anti-tumor response. These engineered cells demonstrated a reduction in cell exhaustion and greater persistence in fighting tumors with higher levels of differentiation, which has been linked to more robust immune responses. These cells also showed good tumor control in both in vitro and in vivo models. While still in its early stages, research like this highlights the growing momentum of scientific development into CAR-T therapy. This strategy could help improve CAR-T therapies in patients who do not initially respond well to treatment, making these incredible therapies more accessible to more patients. Read more in Nature ➡️ <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FeaYYUvJw&amp;urlhash=TS0H&amp;trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/eaYYUvJw</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmanufacturingbrighterfutures&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#ManufacturingBrighterFutures</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcelltherapy&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CellTherapy</a> <a class="link" 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href="https://www.linkedin.com/company/frederick-national-laboratory-for-cancer-research?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Frederick National Laboratory for Cancer Research</a> and the <a class="link" href="https://www.linkedin.com/company/nationalcancerinstitute?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>National Cancer Institute (NCI)</a> have developed a cutting-edge CRISPR screening platform, revolutionizing how we identify protein-molecule interactions crucial for drug development. 🧬🔬 ❗️ Why It Is Important: ⭐️ Advanced CRISPRa Technology It activates genes to increase receptor presence on cell surfaces, simplifying interaction detection. ⭐️ Enhanced Sensitivity Nano-sized magnetic beads improve detection of low-affinity interactions, essential for effective and safe drugs. ⭐️ Major Discovery The research identified a new low-affinity protein-receptor pair, paving the way for innovative treatments. ⭐️ Public gRNA Libraries New libraries are now available in the Addgene database to support global research efforts. This platform could drive the development of next-generation drugs, making treatments more efficient and accessible. Congratulations to the brilliant minds pushing the boundaries of science: Liping Yang, <a class="link" href="https://www.linkedin.com/in/drtpsheets?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Timothy Sheets, M.S., Ph.D.</a>, Yang Feng, Pradip Bajgain, Kuo-Sheng Hsu, Daeho So, Steven Seaman, Jaewon Lee, Ling Lin, Christine N. Evans, Mary R. 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<li class="ellipsis-menu__item border-t-1 border-solid border-color-border-low-emphasis first-of-type:border-none flex"> <a href="/uas/login?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Fposts%2Fyou-ren-wu-96a72b1a2_celltherapy-cancerresearch-immunotherapy-activity-7224595490468741122-WEOM&amp;trk=public_post_ellipsis-menu-semaphore-sign-in-redirect&amp;guestReportContentType=POST&amp;_f=guest-reporting" data-tracking-control-name="public_post_ellipsis-menu-semaphore-sign-in-redirect" data-tracking-will-navigate data-item-type="semaphore" data-semaphore-content-type="POST" data-semaphore-content-urn="urn:li:activity:7224595490468741122" data-semaphore-tracking-prefix="public_post_ellipsis-menu-semaphore" data-is-logged-in="false" data-modal="semaphore__toggle" class="semaphore__toggle visited:text-color-text-secondary ellipsis-menu__semaphore ellipsis-menu__item-button flex items-center w-full p-1 cursor-pointer font-sans text-sm font-bold link-styled focus:link-styled 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By deleting the adhesion ligands CD54 and CD58, donor immune cells show reduced rejection by host NK cells while maintaining antitumor functionality. Key Findings: ⭐ Immune-Evasion: Inspired by tumor and viral escape mechanisms. ⭐ Reduced Rejection: Deletion of CD54 and CD58 lowers rejection rates. ⭐ Maintained Functionality: Ensures antitumor effectiveness remains intact. This approach enhances the success of allogeneic immunotherapies, potentially leading to broader clinical applications. Full article: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FgeyYWH9P&amp;urlhash=SKD9&amp;trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/geyYWH9P</a> - I am currently working on integrating OCR monitoring into the CAR-T cell manufacturing process. My goal is to explore the potential of selecting CAR-T cells with high OCR to enhance their therapeutic effectiveness. I am seeking collaborators for this research proposal. If you are interested in this project, please feel free to reach out to me. <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcelltherapy&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CellTherapy</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerresearch&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CancerResearch</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fimmunotherapy&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#Immunotherapy</a> <a class="link" 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babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">𝐓𝐡𝐞 𝐠𝐥𝐨𝐛𝐚𝐥 𝐦𝐮𝐥𝐭𝐢 𝐜𝐚𝐧𝐜𝐞𝐫 𝐞𝐚𝐫𝐥𝐲 𝐝𝐞𝐭𝐞𝐜𝐭𝐢𝐨𝐧 𝐦𝐚𝐫𝐤𝐞𝐭 𝐬𝐢𝐳𝐞 𝐢𝐬 𝐞𝐱𝐩𝐞𝐜𝐭𝐞𝐝 𝐭𝐨 𝐫𝐞𝐚𝐜𝐡 𝐔𝐒𝐃 𝟑,𝟗𝟑𝟒.𝟕𝟗 𝐦𝐢𝐥𝐥𝐢𝐨𝐧 𝐛𝐲 𝟐𝟎𝟑𝟐, 𝐞𝐱𝐡𝐢𝐛𝐢𝐭𝐢𝐧𝐠 𝐭𝐡𝐞 𝐂𝐀𝐆𝐑 𝐨𝐟 𝟏𝟔.𝟕% 𝐝𝐮𝐫𝐢𝐧𝐠 𝐭𝐡𝐞 𝐟𝐨𝐫𝐞𝐜𝐚𝐬𝐭 𝐩𝐞𝐫𝐢𝐨𝐝. 𝙁𝙤𝙧 𝙈𝙤𝙧𝙚 𝙍𝙚𝙥𝙤𝙧𝙩 𝘿𝙚𝙩𝙖𝙞𝙡𝙨, 𝙑𝙞𝙨𝙞𝙩: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Frb%2Egy%2Fzagu4q&amp;urlhash=VD_B&amp;trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://rb.gy/zagu4q</a>   The <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2FmultiAbRcancerAbRearlyAbRdetectionAbRmarket&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#multi_cancer_early_detection_market</a> is rapidly evolving, driven by advances in genomics, biotechnology, and artificial intelligence. This market focuses on the development and commercialization of diagnostic tests capable of detecting multiple cancer types from a single sample, often using non-invasive methods such as blood tests. The aim is to identify cancer at an early, more treatable stage, improving patient outcomes and reducing healthcare costs. <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmulticancerearlydetection&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#multicancerearlydetection</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcancerdiagnosis&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#cancerdiagnosis</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fearlydetection&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#earlydetection</a> <a 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!text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">Did you miss it -- Dr. Maggie Bartlett's discussion of multimodal single cell sequencing for biomarker discovery, mechanisms of persistence, and viral kinetics? Find it and a replay of all our webinars here: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2Fe4-_4F9P&amp;urlhash=hlz4&amp;trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/e4-_4F9P</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fforefrontofvirology&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#ForefrontOfVirology</a></p> <!----> </div> <ul class="grid grid-cols-6 grid-rows-[60%_40%] w-main-feed-card-media feed-images-content list-none pl-0 " data-test-id="feed-images-content"> <li class="bg-color-background-container-tint text-[0px] col-span-full row-span-full " data-test-id="feed-images-content__list-item" data-position="0"> <img class="lazy-load w-full object-cover object-center h-full 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𝗚𝗲𝘁 𝗠𝗼𝗿𝗲 𝗗𝗲𝘁𝗮𝗶𝗹𝘀: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Frb%2Egy%2Ftkk6to&amp;urlhash=zbuH&amp;trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://rb.gy/tkk6to</a> Increasing investments in <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fresearch&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#research</a> and development in the field of cancer research, along with a rising demand for personalized medicines, are expected to be significant factors contributing to market growth. <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fresearchgradeproteins&amp;trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" 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class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="feed-reshare-content__commentary"><a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fscientificwednesday&amp;trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#ScientificWednesday</a>: Exciting News in Drug Discovery! 🚀 Researchers at the <a class="link" href="https://www.linkedin.com/company/frederick-national-laboratory-for-cancer-research?trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>Frederick National Laboratory for Cancer Research</a> and the <a class="link" href="https://www.linkedin.com/company/nationalcancerinstitute?trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>National Cancer Institute (NCI)</a> have developed a cutting-edge CRISPR screening platform, revolutionizing how we identify protein-molecule interactions crucial for drug development. 🧬🔬 ❗️ Why It Is Important: ⭐️ Advanced CRISPRa Technology It activates genes to increase receptor presence on cell surfaces, simplifying interaction detection. ⭐️ Enhanced Sensitivity Nano-sized magnetic beads improve detection of low-affinity interactions, essential for effective and safe drugs. ⭐️ Major Discovery The research identified a new low-affinity protein-receptor pair, paving the way for innovative treatments. ⭐️ Public gRNA Libraries New libraries are now available in the Addgene database to support global research efforts. This platform could drive the development of next-generation drugs, making treatments more efficient and accessible. Congratulations to the brilliant minds pushing the boundaries of science: Liping Yang, <a class="link" href="https://www.linkedin.com/in/drtpsheets?trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>Timothy Sheets, M.S., Ph.D.</a>, Yang Feng, Pradip Bajgain, Kuo-Sheng Hsu, Daeho So, Steven Seaman, Jaewon Lee, Ling Lin, Christine N. Evans, Mary R. Guest, <a class="link" href="https://www.linkedin.com/in/raj-chari-14970b14?trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>Raj Chari</a>, and Brad St. Croix ! 👏💡 🔎 Read more: <a class="link" href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Flnkd%2Ein%2FgQzxcSxs&amp;urlhash=Buzt&amp;trk=public_post_reshare-text" target="_self" rel="nofollow" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>https://lnkd.in/gQzxcSxs</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdrugdiscovery&amp;trk=public_post_reshare-text" target="_self" data-tracking-control-name="public_post_reshare-text" data-tracking-will-navigate>#DrugDiscovery</a> <a class="link" 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Ori Biotech" class="absolute left-0 top-0 h-full w-full z-1 !border-0" data-tracking-control-name="link-overlay-public_post" href="https://www.linkedin.com/posts/oribiotech-ltd_manufacturingbrighterfutures-celltherapy-activity-7262118521369673729-oq8C" target="_self"></a> <article class="relative px-2 pb-0 bg-color-background-container container-lined pt-1.5 main-feed-activity-card related-posts__crosslink" data-activity-urn="urn:li:activity:7262118521369673729" data-featured-activity-urn="urn:li:activity:7262118521369673729" data-attributed-urn="urn:li:share:7262118520166002688"> <!----> <!----> <div class="flex"> <div class="base-main-feed-card__entity-lockup"> <div class="flex items-center font-sans mb-1" data-test-id="main-feed-activity-card__entity-lockup"> <a href="https://uk.linkedin.com/company/oribiotech-ltd?trk=public_post_feed-actor-image" class="relative" data-tracking-control-name="public_post_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative 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text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 1w <!----> </time> <!----> </span> </div> <!----> </div> </div> <div class="ellipsis-menu absolute right-0 top-0 main-feed-activity-card__ellipsis-menu !top-auto !relative !mr-1" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/671xosfpvk4c0kqtyl87hashi"></icon> </button> <ul class="collapsible-dropdown__list hidden container-raised absolute w-auto overflow-y-auto flex-col items-stretch z-1 bottom-auto top-[100%]" role="menu" tabindex="-1"> <li class="ellipsis-menu__item border-t-1 border-solid border-color-border-low-emphasis first-of-type:border-none flex"> <a href="/uas/login?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Fposts%2Foribiotech-ltd_manufacturingbrighterfutures-celltherapy-activity-7262118521369673729-oq8C&amp;trk=public_post_ellipsis-menu-semaphore-sign-in-redirect&amp;guestReportContentType=POST&amp;_f=guest-reporting" data-tracking-control-name="public_post_ellipsis-menu-semaphore-sign-in-redirect" data-tracking-will-navigate data-item-type="semaphore" data-semaphore-content-type="POST" data-semaphore-content-urn="urn:li:activity:7262118521369673729" data-semaphore-tracking-prefix="public_post_ellipsis-menu-semaphore" data-is-logged-in="false" data-modal="semaphore__toggle" class="semaphore__toggle visited:text-color-text-secondary ellipsis-menu__semaphore ellipsis-menu__item-button flex items-center w-full p-1 cursor-pointer font-sans text-sm font-bold link-styled focus:link-styled link:no-underline active:bg-color-background-container-tint focus:bg-color-background-container-tint hover:bg-color-background-container-tint outline-offset-[-2px]"> <!----> <icon class="ellipsis-menu__item-icon text-color-text h-[24px] w-[24px] mr-1" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/iq0x9q37wj214o129ai1yjut"> </icon> Report this post </a> <!----> </li> <!----> </ul> <!----> </div> </div> </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">🔬Could an on/off switch improve the safety and efficacy of CAR-T therapy? Researchers in Lausanne, Switzerland, have developed a way to use oral medication to give more control over CAR-T treatments – an important step toward making these therapies more adaptable. “We have potentially addressed [safety and efficacy] issues by engineering on and off switches that are engaged by drugs that have been approved by regulatory agencies and are already in use in the clinic. This should hasten the advancement of these remotely controlled CAR-T cells into clinical trials.” said <a class="link" href="https://ch.linkedin.com/in/melita-irving-b9526032?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Melita Irving</a>, PhD researcher at <a class="link" href="https://www.linkedin.com/company/ludwig-institute-for-cancer-research?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Ludwig Cancer Research</a>. Using well-established oral drugs to manage CAR-T activity could not only improve safety but also helps mitigate T cell exhaustion – improving response durability. 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on mobile--> <button aria-label="한국어 (Korean)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-ko_KR" data-locale="ko_KR" role="menuitem" lang="ko_KR"> 한국어 (Korean) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="मराठी (Marathi)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-mr_IN" data-locale="mr_IN" role="menuitem" lang="mr_IN"> मराठी (Marathi) </button> </li> <li 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language-selector__link !font-regular" data-tracking-control-name="language-selector-nl_NL" data-locale="nl_NL" role="menuitem" lang="nl_NL"> Nederlands (Dutch) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Norsk (Norwegian)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-no_NO" data-locale="no_NO" role="menuitem" lang="no_NO"> Norsk (Norwegian) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="ਪੰਜਾਬੀ (Punjabi)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-pa_IN" data-locale="pa_IN" role="menuitem" lang="pa_IN"> ਪੰਜਾਬੀ (Punjabi) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Polski (Polish)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-pl_PL" data-locale="pl_PL" role="menuitem" lang="pl_PL"> Polski (Polish) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Português (Portuguese)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-pt_BR" data-locale="pt_BR" role="menuitem" lang="pt_BR"> Português (Portuguese) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Română (Romanian)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-ro_RO" data-locale="ro_RO" role="menuitem" lang="ro_RO"> Română (Romanian) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Русский (Russian)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-ru_RU" data-locale="ru_RU" role="menuitem" lang="ru_RU"> Русский (Russian) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Svenska (Swedish)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-sv_SE" data-locale="sv_SE" role="menuitem" lang="sv_SE"> Svenska (Swedish) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="తెలుగు (Telugu)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-te_IN" data-locale="te_IN" role="menuitem" lang="te_IN"> తెలుగు (Telugu) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="ภาษาไทย (Thai)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-th_TH" data-locale="th_TH" role="menuitem" lang="th_TH"> ภาษาไทย (Thai) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Tagalog (Tagalog)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-tl_PH" data-locale="tl_PH" role="menuitem" lang="tl_PH"> Tagalog (Tagalog) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Türkçe (Turkish)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-tr_TR" data-locale="tr_TR" role="menuitem" lang="tr_TR"> Türkçe (Turkish) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Українська (Ukrainian)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-uk_UA" data-locale="uk_UA" role="menuitem" lang="uk_UA"> Українська (Ukrainian) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="Tiếng Việt (Vietnamese)" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-vi_VN" data-locale="vi_VN" role="menuitem" lang="vi_VN"> Tiếng Việt (Vietnamese) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="简体中文 (Chinese (Simplified))" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-zh_CN" data-locale="zh_CN" role="menuitem" lang="zh_CN"> 简体中文 (Chinese (Simplified)) </button> </li> <li class="language-selector__item" role="presentation"> <!-- Adding aria-label to both the li and the button because screen reader focus goes to button on desktop and li on mobile--> <button aria-label="正體中文 (Chinese (Traditional))" class="font-sans text-xs link block py-[5px] px-2 w-full hover:cursor-pointer hover:bg-color-action hover:text-color-text-on-dark focus:bg-color-action focus:text-color-text-on-dark language-selector__link !font-regular" data-tracking-control-name="language-selector-zh_TW" data-locale="zh_TW" role="menuitem" lang="zh_TW"> 正體中文 (Chinese 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