CINXE.COM

<!DOCTYPE html><html data-wf-domain="www.cas.org" data-wf-page="65086939056db19f33851ef6" data-wf-site="650861f00f97fe8153979335" lang="en" data-wf-locale="zh-CN" data-wf-collection="65086938056db19f33851eb5" data-wf-item-slug="defining-the-path-to-tbk1-inhibition-with-qsar-modeling"><head><meta charset="utf-8"/><title>Defining the path to TBK1 inhibition with QSAR modeling | CAS</title><link rel="alternate" hrefLang="x-default" href="https://www.cas.org/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><link rel="alternate" hrefLang="en" href="https://www.cas.org/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><link rel="alternate" hrefLang="pt-BR" href="https://www.cas.org/pt-br/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><link rel="alternate" hrefLang="ko-KR" href="https://www.cas.org/ko/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><link rel="alternate" hrefLang="es-ES" href="https://www.cas.org/es-es/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><link rel="alternate" hrefLang="zh-CN" href="https://www.cas.org/zh-hans/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><link rel="alternate" hrefLang="ja" href="https://www.cas.org/ja/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling"/><meta content="Why are there no FDA approved TBK1 (TANK-binding kinase) inhibitors on the market, despite the key role it plays in the pathophysiology of many diseases." name="description"/><meta content="Defining the path to TBK1 inhibition with QSAR modeling" property="og:title"/><meta content="Why are there no FDA approved TBK1 (TANK-binding kinase) inhibitors on the market, despite the key role it plays in the pathophysiology of many diseases." property="og:description"/><meta content="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image.jpg" property="og:image"/><meta content="Defining the path to TBK1 inhibition with QSAR modeling" property="twitter:title"/><meta content="Why are there no FDA approved TBK1 (TANK-binding kinase) inhibitors on the market, despite the key role it plays in the pathophysiology of many diseases." property="twitter:description"/><meta content="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image.jpg" property="twitter:image"/><meta property="og:type" content="website"/><meta content="summary_large_image" name="twitter:card"/><meta content="width=device-width, initial-scale=1" name="viewport"/><link href="https://cdn.prod.website-files.com/650861f00f97fe8153979335/css/cas-org.a6535ac52.min.css" rel="stylesheet" type="text/css"/><script type="text/javascript">!function(o,c){var n=c.documentElement,t=" w-mod-";n.className+=t+"js",("ontouchstart"in o||o.DocumentTouch&&c instanceof DocumentTouch)&&(n.className+=t+"touch")}(window,document);</script><link href="https://cdn.prod.website-files.com/650861f00f97fe8153979335/6585a20f2b9c762a8e082a87_cas-favicon.png" rel="shortcut icon" type="image/x-icon"/><link href="https://cdn.prod.website-files.com/650861f00f97fe8153979335/6585a218bfa3f8e706a9b92a_cas-webclip.png" rel="apple-touch-icon"/><link href="https://www.cas.org/zh-hans/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" rel="canonical"/><link href="rss.xml" rel="alternate" title="RSS Feed" type="application/rss+xml"/><script> window.dataLayer = window.dataLayer ||[]; function gtag(){dataLayer.push(arguments);} gtag('consent','default',{ 'ad_storage':'denied', 'analytics_storage':'denied', 'ad_user_data':'denied', 'ad_personalization':'denied', 'personalization_storage':'denied', 'functionality_storage':'granted', 'security_storage':'granted', 'wait_for_update': 500 }); gtag("set", "ads_data_redaction", true); </script> <script src="https://cmp.osano.com/16BPzAUFV1UoQ26HU/a9d65c21-17eb-4eec-b081-a08a1ff580e7/osano.js"></script> <script async src="https://www.googletagmanager.com/gtag/js?id=G-0LKKGQYK33"></script> <script type="text/javascript" src="//cdn-4.convertexperiments.com/js/10047855-100411829.js"></script>  <script type="text/javascript" id="hs-script-loader" async defer src="//js.hs-scripts.com/47352454.js"></script>   <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-5RS86Q');</script>  <style>.box-1,.box-2{height:100%;text-align:center}*{-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;-o-font-smoothing:antialiased}main ul li::marker{content:"\2014"}.osano-cm-drawer-toggle .osano-cm-label{color:#102a43}a{text-decoration:none}button{background-color:unset;padding:unset;text-align:inherit}section{position:relative}:where([data-container]){position:relative;width:100%;max-width:90rem;margin-right:auto;margin-left:auto;padding-top:var(--scale--scale-128px);padding-right:var(--scale--scale-32px);padding-bottom:var(--scale--scale-128px);padding-left:var(--scale--scale-32px)}.container:tiny{overflow:hidden}.em-dash-list{list-style:none;padding-left:0;margin-left:20px}.em-dash-list li{align-items:baseline}.em-dash-list li:before{content:"\2014";color:#41b6e6;display:inline-block;width:1em;margin-right:6px}.styled-table{border-collapse:collapse;margin:25px 0;font-size:1rem;font-family:sans-serif;min-width:400px;box-shadow:0 0 15px rgba(0,0,0,.15)}.styled-table thead tr{background-color:#41b6e6;color:#fff;text-align:left}.styled-table td,.styled-table th{padding:12px 15px}.styled-table tbody tr{border-bottom:1px solid #dcdcdc}.styled-table tbody tr:nth-of-type(2n){background-color:#fff}.styled-table tbody tr:last-of-type{border-bottom:2px solid #41b6e6}.styled-table tbody tr.active-row{font-weight:700;color:#41b6e6}.grid{display:grid;grid-template-columns:1fr 1fr;gap:20px}.box,.col{padding:20px}.box-1{background:#0032a0;color:#fff}.box-2{background:#ffc72c;color:#0032a0}@media (max-width:600px){.grid{grid-template-columns:1fr}}</style> <style media="print"> /* Hide header and footer */ .site-header, .site-footer_component { display: none !important; } /* Remove default margins */ @page { margin: 0; } body { margin: 1cm; } </style><script> window.dataLayer=window.dataLayer||[],window.dataLayer.push({event:"view_article",articleCategory:"Insights Report",publishDate:"Sep 19, 2024"}); </script> <script type="application/ld+json"> { "@context": "http://schema.org", "@type": "Article", "headline": "Defining the path to TBK1 inhibition with QSAR modeling", "author": [ { "@type": "Person", "name": "CAS Science Team", "url": "https://www.cas.org/author/cas-science-team" }, { "@type": "Person", "name": "", "url": "https://www.cas.org/author/" }, { "@type": "Person", "name": "", "url": "https://www.cas.org/author/" }, { "@type": "Person", "name": "", "url": "https://www.cas.org/author/" } ], "datePublished": "Sep 19, 2024", "description": "Why are there no FDA approved TBK1 (TANK-binding kinase) inhibitors on the market, despite the key role it plays in the pathophysiology of many diseases. ", "publisher": { "@type": "Organization", "name": "CAS" } } </script>  <script defer src="https://cdn.jsdelivr.net/npm/@finsweet/attributes-socialshare@1/socialshare.js"></script>  <script defer src="https://cdn.jsdelivr.net/npm/@finsweet/attributes-richtext@1/richtext.js"></script>  <script defer src="https://cdn.jsdelivr.net/npm/@finsweet/attributes-toc@1/toc.js"></script><script src="https://cdn.prod.website-files.com/650861f00f97fe8153979335%2F6544eda5f000985a163a8687%2F671a4cc4f8d90a0a94a07cb1%2Ffinsweetcomponentsconfig-1.0.1.js" type="module" async="" siteId="650861f00f97fe8153979335" finsweet="components"></script></head><body><div class="w-embed w-iframe">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5RS86Q" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> </div><div id="page-anchor" class="page-anchor"></div><div class="page-wrapper"><header class="site-header"><div data-w-id="dff35351-dfb0-8d4f-486b-faee40785252" class="top-nav-wrapper"><div class="banner-component"><div>CAS STNext® Webinar Best practices for advanced structure searching in CAS STNext</div><a href="https://www.cas.org/resources/webinar/whats-new-scifinder-2024-sep" class="banner__link w-inline-block"><div class="banner__text">立即注册</div><div class="banner__icon w-embed"><svg width="18" height="18" viewBox="0 0 18 18" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M10.8698 4.28285C10.5773 4.57535 10.5773 5.04785 10.8698 5.34035L13.7798 8.25035H2.40234C1.98984 8.25035 1.65234 8.58785 1.65234 9.00035C1.65234 9.41285 1.98984 9.75035 2.40234 9.75035H13.7873L10.8773 12.6603C10.5848 12.9528 10.5848 13.4254 10.8773 13.7179C11.1698 14.0104 11.6423 14.0104 11.9348 13.7179L16.1273 9.52535C16.4198 9.23285 16.4198 8.76035 16.1273 8.46785L11.9273 4.28285C11.6423 3.99035 11.1623 3.99035 10.8698 4.28285Z" fill="currentColor"/> </svg></div></a></div><div class="courtesy_nav-component"><div data-animation="default" data-collapse="small" data-duration="400" data-easing="ease" data-easing2="ease" role="banner" class="courtesy-navbar w-nav"><div class="courtesy-navbar_container"><div class="courtesy-navbar__wrapper"><div class="courtesy-navbar__search-component"><form action="/zh-hans/search" typeof="WebSite" vocab="https://schema.org/" class="search w-form"><input class="search__input w-input" maxlength="256" name="query" typeof="SearchAction" placeholder="Search…" property="query-input" type="search" id="search" required=""/><input type="hidden" property="target" value="https://www.cas.org/search?query={search_term_string}"/><input type="submit" class="button button__search w-button" value="检索"/></form></div><div class="courtesy-navbar__language-wrapper"><nav role="navigation" class="courtesy-nav__menu w-nav-menu"><a href="/zh-hans/training" class="courtesy-nav__link w-nav-link">培训内容</a><a href="/zh-hans/contact" class="courtesy-nav__link w-nav-link">联系我们</a><a href="/zh-hans/cas-solutions-login" class="courtesy-nav__link w-nav-link">登录</a></nav><div class="menu-button-4 w-nav-button"><div class="icon-2 w-icon-nav-menu"></div></div><div data-hover="false" data-delay="0" class="language__dropdown w-dropdown"><div class="language__dropdown--toggle w-dropdown-toggle"><div class="language__dropdown--icon w-icon-dropdown-toggle"></div><div class="language__dropdown--prompt">选择语言</div></div><nav class="language__dropdown--locales w-dropdown-list"><div class="language__dropdown--locales-wrapper w-locales-list"><div role="list" class="language__dropdown--locales-list w-locales-items"><div role="listitem" class="language__dropdown--locale w-locales-item"><a hreflang="en" href="/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="language__dropdown--locale-link">English</a></div><div role="listitem" class="language__dropdown--locale w-locales-item"><a hreflang="pt-BR" href="/pt-br/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="language__dropdown--locale-link">Portuguese</a></div><div role="listitem" class="language__dropdown--locale w-locales-item"><a hreflang="ko-KR" href="/ko/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="language__dropdown--locale-link">Korean</a></div><div role="listitem" class="language__dropdown--locale w-locales-item"><a hreflang="es-ES" href="/es-es/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="language__dropdown--locale-link">Spanish</a></div><div role="listitem" class="language__dropdown--locale w-locales-item"><a hreflang="zh-CN" href="/zh-hans/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" aria-current="page" class="language__dropdown--locale-link w--current">Chinese</a></div><div role="listitem" class="language__dropdown--locale w-locales-item"><a hreflang="ja" href="/ja/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="language__dropdown--locale-link">Japanese</a></div></div></div></nav></div></div></div></div></div></div></div><div data-animation="default" class="site-navbar w-nav" data-easing2="ease" fs-scrolldisable-element="smart-nav" data-easing="ease" data-collapse="medium" data-w-id="215f21f3-d3c1-74ca-22fa-c34c35e3158b" role="banner" data-duration="400"><div class="site-nav__container"><a href="https://www.cas.org" class="navbar_logo-link w-nav-brand"><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/65babbec1c38d54bcc033f7c_CAS_PREF_3C_RGB_POS.svg" loading="lazy" width="126" alt="CAS Logo" class="navbar_logo"/></a><nav role="navigation" class="site-navbar_menu is-page-height-tablet w-nav-menu"><div class="mobile-search_wrapper"><form action="/zh-hans/search" class="mobile-search_component w-form"><input class="mobile-search_input w-input" maxlength="256" name="query" placeholder="" type="search" id="mobile-search" required=""/><input type="submit" class="mobile-search_button w-button" value="Search"/></form></div><div data-hover="false" data-delay="200" data-w-id="215f21f3-d3c1-74ca-22fa-c34c35e31596" class="navbar-main_menu-dropdown w-dropdown"><div class="navbar_dropdown-toggle w-dropdown-toggle"><div>解决方案</div><div class="dropdown-chevron w-embed"><svg width=" 100%" height=" 100%" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M2.55806 6.29544C2.46043 6.19781 2.46043 6.03952 2.55806 5.94189L3.44195 5.058C3.53958 4.96037 3.69787 4.96037 3.7955 5.058L8.00001 9.26251L12.2045 5.058C12.3021 4.96037 12.4604 4.96037 12.5581 5.058L13.4419 5.94189C13.5396 6.03952 13.5396 6.19781 13.4419 6.29544L8.17678 11.5606C8.07915 11.6582 7.92086 11.6582 7.82323 11.5606L2.55806 6.29544Z" fill="currentColor"/> </svg></div></div><nav class="navbar-main_dropdown-list navbar-column-4-width w-dropdown-list"><div class="navbar-main_dropdown-content"><div id="w-node-da5a10a2-dd85-3827-8c9d-eb3bf354b8de-f9289f4b" class="navbar_dropdown-link-list"><div class="nav_dropdown-link-wrap"><a href="/zh-hans/solutions/biofinder-discovery-platform" class="nav__dropdown-platform-link">CAS BioFinder Discovery Platform</a></div><div id="w-node-da5a10a2-dd85-3827-8c9d-eb3bf354b8e2-f9289f4b" class="nav_dropdown-link-wrap"><a href="/zh-hans/solutions/cas-scifinder-discovery-platform" class="nav__dropdown-platform-link">CAS SciFinder Discovery Platform</a><div class="nav__link-list"><a href="/zh-hans/solutions/cas-scifinder-discovery-platform/cas-scifinder" class="nav__dropdown-link w-inline-block"><div>CAS SciFinder</div></a><a href="/zh-hans/solutions/cas-scifinder-discovery-platform/cas-formulus" class="nav__dropdown-link w-inline-block"><div>CAS Formulus</div></a><a href="/zh-hans/solutions/cas-scifinder-discovery-platform/cas-analytical-methods" class="nav__dropdown-link w-inline-block"><div>CAS Analytical Methods</div></a></div></div></div><div id="w-node-da5a10a2-dd85-3827-8c9d-eb3bf354b8ef-f9289f4b" class="navbar_dropdown-link-list"><div class="nav_dropdown-link-wrap"><a href="/zh-hans/solutions/stn-ip-protection-suite" class="nav__dropdown-platform-link">STN IP Protection Suite</a><div class="nav__link-list"><a href="/zh-hans/solutions/stn-ip-protection-suite/stnext" class="nav__dropdown-link w-inline-block"><div>CAS STNext</div></a><a href="/zh-hans/solutions/stn-ip-protection-suite/cas-scientific-patent-explorer" class="nav__dropdown-link w-inline-block"><div>CAS Scientific Patent Explorer</div></a><a href="/zh-hans/solutions/stn-ip-protection-suite/patmon" class="nav__dropdown-link w-inline-block"><div>FIZ PatMon</div></a><a href="/zh-hans/solutions/stn-ip-protection-suite/cas-search-guard" class="nav__dropdown-link w-inline-block"><div>CAS Search Guard</div></a></div></div></div><div id="w-node-da5a10a2-dd85-3827-8c9d-eb3bf354b900-f9289f4b" class="navbar_dropdown-link-list"><div class="nav_dropdown-link-wrap"><a href="/zh-hans/solutions/cas-custom-services" class="nav__dropdown-platform-link">CAS Custom Services</a><div class="nav__link-list"><a href="/zh-hans/solutions/cas-custom-services/ip-services" class="nav__dropdown-link w-inline-block"><div>CAS IP Services</div></a><a href="/zh-hans/solutions/cas-registry-services" class="nav__dropdown-link w-inline-block"><div>CAS Registry Services</div></a></div></div></div><div id="w-node-da5a10a2-dd85-3827-8c9d-eb3bf354b90b-f9289f4b" class="navbar_dropdown-link-list"><div class="nav_dropdown-link-wrap"><a href="/zh-hans/solutions/other-solutions" class="nav__dropdown-platform-link">Other CAS Solutions</a><div class="nav__link-list"><a href="/zh-hans/solutions/other-solutions/cas-chemical-compliance-index" class="nav__dropdown-link w-inline-block"><div>CAS Chemical <br/>Compliance Index</div></a><a href="/zh-hans/solutions/other-solutions/chemzent" class="nav__dropdown-link w-inline-block"><div>ChemZent</div></a><a href="/zh-hans/solutions/other-solutions/cas-chemical-supplier-insights" class="nav__dropdown-link w-inline-block"><div>CAS Chemical <br/>Supplier Insights</div></a></div></div></div></div><a href="/zh-hans/solutions" class="navbar_button-full-width w-inline-block"><div>查看所有解决方案</div><div class="button-icon-small w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--ic" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 24 24"><path fill="currentColor" d="M6 7c0 .55.45 1 1 1h7.59l-8.88 8.88a.996.996 0 1 0 1.41 1.41L16 9.41V17c0 .55.45 1 1 1s1-.45 1-1V7c0-.55-.45-1-1-1H7c-.55 0-1 .45-1 1"></path></svg></div></a></nav></div><div data-hover="false" data-delay="200" data-w-id="6ce5613a-a398-6459-54a8-c1335306637d" class="navbar-main_menu-dropdown w-dropdown"><div class="navbar_dropdown-toggle w-dropdown-toggle"><div>服务行业</div><div class="dropdown-chevron w-embed"><svg width=" 100%" height=" 100%" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M2.55806 6.29544C2.46043 6.19781 2.46043 6.03952 2.55806 5.94189L3.44195 5.058C3.53958 4.96037 3.69787 4.96037 3.7955 5.058L8.00001 9.26251L12.2045 5.058C12.3021 4.96037 12.4604 4.96037 12.5581 5.058L13.4419 5.94189C13.5396 6.03952 13.5396 6.19781 13.4419 6.29544L8.17678 11.5606C8.07915 11.6582 7.92086 11.6582 7.82323 11.5606L2.55806 6.29544Z" fill="currentColor"/> </svg></div></div><nav class="navbar-main_dropdown-list navbar-column-2_width navbar_industries w-dropdown-list"><div class="navbar-main_dropdown-content navbar-column-2"><div class="navbar_dropdown-link-list"><div id="w-node-_6ce5613a-a398-6459-54a8-c13353066388-f9289f4b" class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/industries/agriculture" class="nav__dropdown-link w-inline-block"><div>农业</div></a><a href="/zh-hans/industries/batteries" class="nav__dropdown-link w-inline-block"><div>电池</div></a><a href="/zh-hans/industries/business-of-science" class="nav__dropdown-link w-inline-block"><div>商业</div></a><a href="/zh-hans/industries/coatings-and-inks" class="nav__dropdown-link w-inline-block"><div>涂料与墨水</div></a></div></div></div><div class="navbar_dropdown-link-list"><div class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/industries/drug-discovery" class="nav__dropdown-link w-inline-block"><div>药物研发</div></a><a href="/zh-hans/industries/electronics-and-materials" class="nav__dropdown-link w-inline-block"><div>电子材料</div></a><a href="/zh-hans/industries/plastics-and-polymers" class="nav__dropdown-link w-inline-block"><div>塑料与聚合物</div></a><a href="/zh-hans/industries/sustainability" class="nav__dropdown-link w-inline-block"><div>可持续性发展</div></a></div></div></div></div><a href="/zh-hans/industries/industries" class="navbar_button-full-width w-inline-block"><div>View all industries</div><div class="button-icon-small w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--ic" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 24 24"><path fill="currentColor" d="M6 7c0 .55.45 1 1 1h7.59l-8.88 8.88a.996.996 0 1 0 1.41 1.41L16 9.41V17c0 .55.45 1 1 1s1-.45 1-1V7c0-.55-.45-1-1-1H7c-.55 0-1 .45-1 1"></path></svg></div></a></nav></div><div data-hover="false" data-delay="200" data-w-id="f8145756-c9d7-6b6d-891c-40f169ec6d18" class="navbar-main_menu-dropdown w-dropdown"><div class="navbar_dropdown-toggle w-dropdown-toggle"><div>CAS 数据</div><div class="dropdown-chevron w-embed"><svg width=" 100%" height=" 100%" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M2.55806 6.29544C2.46043 6.19781 2.46043 6.03952 2.55806 5.94189L3.44195 5.058C3.53958 4.96037 3.69787 4.96037 3.7955 5.058L8.00001 9.26251L12.2045 5.058C12.3021 4.96037 12.4604 4.96037 12.5581 5.058L13.4419 5.94189C13.5396 6.03952 13.5396 6.19781 13.4419 6.29544L8.17678 11.5606C8.07915 11.6582 7.92086 11.6582 7.82323 11.5606L2.55806 6.29544Z" fill="currentColor"/> </svg></div></div><nav class="navbar-main_dropdown-list navbar-column-2_width w-dropdown-list"><div class="navbar-main_dropdown-content navbar-column-2"><div class="navbar_dropdown-link-list"><div id="w-node-f8145756-c9d7-6b6d-891c-40f169ec6d20-f9289f4b" class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/cas-data/cas-registry" class="nav__dropdown-link w-inline-block"><div>CAS REGISTRY®</div></a><a href="/zh-hans/cas-data/cas-reactions" class="nav__dropdown-link w-inline-block"><div>CAS Reactions</div></a><a href="/zh-hans/cas-data/cas-references" class="nav__dropdown-link w-inline-block"><div>CAS References</div></a></div></div></div><div class="navbar_dropdown-link-list"><div class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/cas-data/cas-patents" class="nav__dropdown-link w-inline-block"><div>CAS Patents</div></a><a href="/zh-hans/cas-data/cas-commercial-sources" class="nav__dropdown-link w-inline-block"><div>CAS Commercial Sources</div></a><a href="/zh-hans/cas-data/cas-formulations" class="nav__dropdown-link w-inline-block"><div>CAS Formulations</div></a><a href="/zh-hans/cas-data/life-sciences-data" class="nav__dropdown-link w-inline-block"><div>CAS Life Sciences</div></a></div></div></div></div><a href="/zh-hans/cas-data" class="navbar_button-full-width w-inline-block"><div>View all CAS Data</div><div class="button-icon-small w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--ic" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 24 24"><path fill="currentColor" d="M6 7c0 .55.45 1 1 1h7.59l-8.88 8.88a.996.996 0 1 0 1.41 1.41L16 9.41V17c0 .55.45 1 1 1s1-.45 1-1V7c0-.55-.45-1-1-1H7c-.55 0-1 .45-1 1"></path></svg></div></a></nav></div><div data-hover="false" data-delay="200" data-w-id="73ecd304-4e29-38f3-18bb-b8cd3eb6ac2b" class="navbar-main_menu-dropdown w-dropdown"><div class="navbar_dropdown-toggle w-dropdown-toggle"><div>资源</div><div class="dropdown-chevron w-embed"><svg width=" 100%" height=" 100%" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M2.55806 6.29544C2.46043 6.19781 2.46043 6.03952 2.55806 5.94189L3.44195 5.058C3.53958 4.96037 3.69787 4.96037 3.7955 5.058L8.00001 9.26251L12.2045 5.058C12.3021 4.96037 12.4604 4.96037 12.5581 5.058L13.4419 5.94189C13.5396 6.03952 13.5396 6.19781 13.4419 6.29544L8.17678 11.5606C8.07915 11.6582 7.92086 11.6582 7.82323 11.5606L2.55806 6.29544Z" fill="currentColor"/> </svg></div></div><nav class="navbar-main_dropdown-list navbar-column-2_width navbar_resources w-dropdown-list"><div class="navbar-main_dropdown-content navbar-column-2 navbar_resources"><div class="navbar_dropdown-link-list"><div id="w-node-_2f9fe6c6-c578-de26-c4e8-58c417e8eb54-f9289f4b" class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/resources/cas-insights" class="nav__dropdown-link w-inline-block"><div>CAS Insights</div></a><a href="/zh-hans/cas-events" class="nav__dropdown-link w-inline-block"><div>活动</div></a><a href="/zh-hans/cas-webinars" class="nav__dropdown-link w-inline-block"><div>网络研讨会</div></a><a href="/zh-hans/resources/white-papers" class="nav__dropdown-link w-inline-block"><div>白皮书</div></a></div></div></div><div class="navbar_dropdown-link-list"><div id="w-node-_2f9fe6c6-c578-de26-c4e8-58c417e8eb63-f9289f4b" class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/resources/case-studies" class="nav__dropdown-link w-inline-block"><div>案例研究</div></a><a href="https://commonchemistry.cas.org/" class="nav__dropdown-link w-inline-block"><div>CAS Common Chemistry</div></a><a href="/zh-hans/resources/chemical-safety-library" class="nav__dropdown-link w-inline-block"><div>皮斯托亚化学品安全数据库</div></a><a href="https://cassi.cas.org/" class="nav__dropdown-link w-inline-block"><div>CAS 来源索引 (CASSI)</div></a></div></div></div></div><a href="/zh-hans/resources" class="navbar_button-full-width w-inline-block"><div>View all resources</div><div class="button-icon-small w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--ic" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 24 24"><path fill="currentColor" d="M6 7c0 .55.45 1 1 1h7.59l-8.88 8.88a.996.996 0 1 0 1.41 1.41L16 9.41V17c0 .55.45 1 1 1s1-.45 1-1V7c0-.55-.45-1-1-1H7c-.55 0-1 .45-1 1"></path></svg></div></a></nav></div><div data-hover="false" data-delay="200" data-w-id="7cad82f7-9dad-9ea8-65e5-8a505736f212" class="navbar-main_menu-dropdown w-dropdown"><div class="navbar_dropdown-toggle w-dropdown-toggle"><div>关于</div><div class="dropdown-chevron w-embed"><svg width=" 100%" height=" 100%" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M2.55806 6.29544C2.46043 6.19781 2.46043 6.03952 2.55806 5.94189L3.44195 5.058C3.53958 4.96037 3.69787 4.96037 3.7955 5.058L8.00001 9.26251L12.2045 5.058C12.3021 4.96037 12.4604 4.96037 12.5581 5.058L13.4419 5.94189C13.5396 6.03952 13.5396 6.19781 13.4419 6.29544L8.17678 11.5606C8.07915 11.6582 7.92086 11.6582 7.82323 11.5606L2.55806 6.29544Z" fill="currentColor"/> </svg></div></div><nav class="navbar-main_dropdown-list navbar-column-2_width navbar_about w-dropdown-list"><div class="navbar-main_dropdown-content navbar-column-2"><div class="navbar_dropdown-link-list"><div id="w-node-_257986f8-6154-22b2-c35d-1ceffe0d3de8-f9289f4b" class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/about-us" class="nav__dropdown-link w-inline-block"><div>关于 CAS</div></a><a href="/zh-hans/about/cas-history" class="nav__dropdown-link w-inline-block"><div>CAS 故事</div></a><a href="/zh-hans/careers" class="nav__dropdown-link w-inline-block"><div>招贤纳士</div></a><a href="/zh-hans/about/futureleaders" class="nav__dropdown-link w-inline-block"><div>未来领袖</div></a></div></div></div><div class="navbar_dropdown-link-list"><div id="w-node-_257986f8-6154-22b2-c35d-1ceffe0d3df4-f9289f4b" class="nav_dropdown-link-wrap"><div class="nav__link-list"><a href="/zh-hans/cas-innovation-incubator" class="nav__dropdown-link w-inline-block"><div>CAS 创新孵化器</div></a><a href="/zh-hans/about/faqs" class="nav__dropdown-link w-inline-block"><div>常见问题</div></a><a href="/zh-hans/press-releases" class="nav__dropdown-link w-inline-block"><div>新闻发布</div></a></div></div></div></div></nav></div><div class="mobile-utility-nav_wrapper"><a href="/zh-hans/training" class="mobile__training-link">训练</a><a href="/zh-hans/cas-solutions-login" class="mobile__training-link">日志登录</a><a href="/zh-hans/contact" class="mobile__training-link">联系我们</a></div><div class="mobile-locales_wrapper w-locales-list"><div data-hover="false" data-delay="0" class="mobile-locales_dropdown w-dropdown"><div class="mobile-locales_dropdown-toggle w-dropdown-toggle"><div class="w-icon-dropdown-toggle"></div><div>Chinese</div></div><nav class="mobile-locales_dropdown-list w-dropdown-list"><div role="list" class="locales-list w-locales-items"><div role="listitem" class="locale_link w-locales-item"><a hreflang="en" href="/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="locale_link">English</a></div><div role="listitem" class="locale_link w-locales-item"><a hreflang="pt-BR" href="/pt-br/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="locale_link">Portuguese</a></div><div role="listitem" class="locale_link w-locales-item"><a hreflang="ko-KR" href="/ko/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="locale_link">Korean</a></div><div role="listitem" class="locale_link w-locales-item"><a hreflang="es-ES" href="/es-es/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="locale_link">Spanish</a></div><div role="listitem" class="locale_link w-locales-item"><a hreflang="zh-CN" href="/zh-hans/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" aria-current="page" class="locale_link w--current">Chinese</a></div><div role="listitem" class="locale_link w-locales-item"><a hreflang="ja" href="/ja/resources/cas-insights/defining-the-path-to-tbk1-inhibition-with-qsar-modeling" class="locale_link">Japanese</a></div></div></nav></div></div></nav><div class="navbar12_menu-button w-nav-button"><div class="menu-icon1"><div class="menu-icon1_line-top"></div><div class="menu-icon1_line-middle"><div class="menu-icon_line-middle-inner"></div></div><div class="menu-icon1_line-bottom"></div></div></div></div></div></header><div class="insights_conversation-hero-wrapper w-condition-invisible"><section class="insights-hero_component"><div class="insights-hero_overlay"><img width="1920" height="1080" alt="Hexagon shaped overlay" src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/65b9650b65450d7eb246fc09_promo-hero.svg" loading="eager" class="insights-hero_overlay-image"/></div><div class="insights-hero_container"><div class="insights-hero_content-wrapper"><div id="w-node-_1e6498af-c968-0c07-a42f-0232e8382a88-33851ef6" class="insights-hero_content"><h1 id="w-node-_1e6498af-c968-0c07-a42f-0232e8382a89-33851ef6" class="insights-hero_title">Defining the path to TBK1 inhibition with QSAR modeling</h1><h2 class="heading-style-h3 text-color-white text-weight-semibold w-dyn-bind-empty"></h2></div><div id="w-node-_4e6c23ef-b675-b790-e868-147ea0673ae4-33851ef6" class="insights-hero_author-image-wrapper"><img src="https://cdn.prod.website-files.com/plugins/Basic/assets/placeholder.60f9b1840c.svg" loading="lazy" alt="Adam Sanford" class="w-dyn-bind-empty"/></div></div></div><div class="insights-hero_background-overlay"></div></section></div><div class="insights_default-hero-wrapper"><section class="insights-hero-default_component"><div class="insights-hero_overlay"><img width="1920" height="1080" alt="Hexagon shaped overlay" src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/65b9650b65450d7eb246fc09_promo-hero.svg" loading="eager" class="insights-hero_overlay-image"/></div><div class="insights-hero_container"><div class="insights-hero_content-wrapper"><div id="w-node-_2ead41d4-c550-37c6-9635-a9e1ceea87aa-33851ef6" class="insights-hero_content"><h1 id="w-node-_2ead41d4-c550-37c6-9635-a9e1ceea87ab-33851ef6" class="insights-hero_title">Defining the path to TBK1 inhibition with QSAR modeling</h1><h2 class="heading-style-h3 text-color-white text-weight-semibold w-condition-invisible w-dyn-bind-empty"></h2></div></div></div></section></div><nav aria-label="Breadcrumb" class="section__breadcrumbs"><div class="container-breadcrumbs"><ol typeof="BreadcrumbList" vocab="https://schema.org/" role="list" class="breadcrumbs w-list-unstyled"><li typeof="ListItem" property="itemListElement" class="breadcrumbs__list-item"><a href="/zh-hans" typeof="WebPage" property="item" class="breadcrumbs__item-link w-inline-block"><div property="name" class="breadcrumbs__list-item--text">主页</div></a><meta property="position" content="1"/><div class="breadcrumbs__separator w-embed"><svg width="32" height="32" viewBox="0 0 32 32" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M20 8L11 23.5885" stroke="currentColor" stroke-width="1.5"/> </svg></div></li><li typeof="ListItem" property="itemListElement" class="breadcrumbs__list-item"><a href="/zh-hans/resources" typeof="WebPage" property="item" class="breadcrumbs__item-link w-inline-block"><div property="name" class="breadcrumbs__list-item--text">Resources</div></a><meta property="position" content="2"/><div class="breadcrumbs__separator w-embed"><svg width="32" height="32" viewBox="0 0 32 32" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M20 8L11 23.5885" stroke="currentColor" stroke-width="1.5"/> </svg></div></li><li typeof="ListItem" property="itemListElement" class="breadcrumbs__list-item"><a href="/zh-hans/resources/cas-insights" typeof="WebPage" property="item" class="breadcrumbs__item-link w-inline-block"><div property="name" class="breadcrumbs__list-item--text">CAS Insights</div></a><meta property="position" content="3"/><div class="breadcrumbs__separator w-embed"><svg width="32" height="32" viewBox="0 0 32 32" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M20 8L11 23.5885" stroke="currentColor" stroke-width="1.5"/> </svg></div></li><li typeof="ListItem" property="itemListElement" class="breadcrumbs__list-item"><div property="name" class="breadcrumbs__list-item--text">Defining the path to TBK1 inhibition with QSAR modeling</div><meta property="position" content="4"/></li></ol></div></nav><div class="background_neutral"><div class="article__layout-container"><main class="article__main-content"><article typeof="Article" id="w-node-_2eefa787-b0ef-b4f6-fa25-16633433b001-33851ef6" class="article__wrapper"><div class="article__image-container"><img src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image.jpg" loading="eager" alt="Male medical worker pipetting chemical in test tube while working in laboratory " sizes="(max-width: 991px) 100vw, (max-width: 1279px) 75vw, (max-width: 1439px) 78vw, 1120px" srcset="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image-p-500.jpg 500w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image-p-800.jpg 800w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image-p-1080.jpg 1080w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb44baaec2d965abc8a429_GettyImages-1395711633_CAS-Insights-Hero-Image.jpg 1920w" class="article__image"/></div><div class="article__byline-wrapper"><div class="article__category-wrapper"><a href="/zh-hans/resources/topic/digital-r-d" class="article-category__link-block w-inline-block"><div class="article__category-list-title">Digital R&D</div><div>,</div></a><a href="/zh-hans/resources/topic/drug-discovery" class="article-category__link-block w-inline-block"><div class="article__category-list-title">Drug Discovery</div><div>,</div></a><a href="/zh-hans/resources/topic/emerging-science" class="article__category-list-title">Emerging Science</a></div><div class="article__share-block"><div class="insights__share-text">Share:</div><a aria-label="facebook" fs-socialshare-element="facebook" href="#" class="social-share-link w-inline-block"><div class="insights-share-icon w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--bx" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 24 24"><path d="M13.397 20.997v-8.196h2.765l.411-3.209h-3.176V7.548c0-.926.258-1.56 1.587-1.56h1.684V3.127A22.336 22.336 0 0 0 14.201 3c-2.444 0-4.122 1.492-4.122 4.231v2.355H7.332v3.209h2.753v8.202h3.312z" fill="currentColor"></path></svg></div></a><a aria-label="Link to X" fs-socialshare-element="twitter" href="#" class="social-share-link w-inline-block"><div class="insights-share-icon w-embed"><svg width="100%" height="100%" viewBox="0 0 24 24" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M17.1761 4H19.9362L13.9061 10.7774L21 20H15.4456L11.0951 14.4066L6.11723 20H3.35544L9.80517 12.7508L3 4H8.69545L12.6279 9.11262L17.1761 4ZM16.2073 18.3754H17.7368L7.86441 5.53928H6.2232L16.2073 18.3754Z" fill="CurrentColor"/> </svg></div></a><a aria-label="Link to LinkedIn" fs-socialshare-element="linkedin" href="#" class="social-share-link w-inline-block"><div class="insights-share-icon w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--bx" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 24 24"><circle cx="4.983" cy="5.009" r="2.188" fill="currentColor"></circle><path d="M9.237 8.855v12.139h3.769v-6.003c0-1.584.298-3.118 2.262-3.118c1.937 0 1.961 1.811 1.961 3.218v5.904H21v-6.657c0-3.27-.704-5.783-4.526-5.783c-1.835 0-3.065 1.007-3.568 1.96h-.051v-1.66H9.237zm-6.142 0H6.87v12.139H3.095z" fill="currentColor"></path></svg></div></a><a aria-label="Link to article" fs-socialshare-element="url" href="#" class="social-share-link w-inline-block"><div class="insights-share-icon w-embed"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" class="iconify iconify--ph" width="100%" height="100%" preserveAspectRatio="xMidYMid meet" viewBox="0 0 256 256"><path fill="currentColor" d="m212.9 122.3l-30.3 30.3a56 56 0 0 1-79.2 0a12 12 0 1 1 16.9-16.9a32.2 32.2 0 0 0 45.3 0l30.3-30.3a32 32 0 0 0-45.3-45.3l-9.6 9.7a12 12 0 0 1-17-17l9.7-9.7a56 56 0 1 1 79.2 79.2ZM115 186.2l-9.6 9.7a32 32 0 0 1-45.3-45.3l30.3-30.3a32.2 32.2 0 0 1 45.3 0a12 12 0 0 0 16.9-16.9a55.9 55.9 0 0 0-79.2 0l-30.3 30.3a56 56 0 0 0 79.2 79.2l9.7-9.7a12 12 0 0 0-17-17Z"></path></svg></div></a></div></div><div class="article__byline-headline">Written by:</div><div class="insights__post-author-block"><a href="/zh-hans/author/cas-science-team" class="insights__post-byline w-inline-block"><div class="insights__post-avatar-wrapper w-condition-invisible"><img loading="lazy" alt="CAS Science Team" src="" class="insights__post-author__avatar w-dyn-bind-empty"/></div><div class="insights__post-author-credit"><div class="insights__post-author-name">CAS Science Team</div><div class="insights__post-author-title w-dyn-bind-empty"></div></div></a><a href="#" class="insights__post-byline w-inline-block w-condition-invisible"><div class="insights__post-avatar-wrapper w-condition-invisible"><img loading="lazy" width="180" height="180" src="" alt="" class="insights__post-author__avatar w-dyn-bind-empty"/></div><div class="insights__post-author-credit"><div class="insights__post-author-name w-dyn-bind-empty"></div><div class="insights__post-author-title w-dyn-bind-empty"></div></div></a><a href="#" class="insights__post-byline w-inline-block w-condition-invisible"><div class="insights__post-avatar-wrapper w-condition-invisible"><img loading="lazy" width="180" height="180" src="" alt="" class="insights__post-author__avatar w-dyn-bind-empty"/></div><div class="insights__post-author-credit"><div class="insights__post-author-name w-dyn-bind-empty"></div><div class="insights__post-author-title w-dyn-bind-empty"></div></div></a><a href="#" class="insights__post-byline w-inline-block w-condition-invisible"><div class="insights__post-avatar-wrapper w-condition-invisible"><img loading="lazy" width="180" height="180" src="" alt="" class="insights__post-author__avatar w-dyn-bind-empty"/></div><div class="insights__post-author-credit"><div class="insights__post-author-name w-dyn-bind-empty"></div><div class="insights__post-author-title w-dyn-bind-empty"></div></div></a></div><div><time class="article__post-publish-date">September 19, 2024</time></div><div fs-toc-element="contents" fs-richtext-element="rich-text" class="article__rich-content w-richtext"><p>TANK-binding kinase 1 (TBK1) plays a key role in various cellular processes and, consequentially, in the pathophysiology of many diseases, from autoimmune diseases to viral infections. While TBK1 has seen increasing amounts of research in the past two decades, there are currently no available FDA-approved TBK1 inhibitors on the market due to safety, efficacy, and resource concerns. </p><p>In this CAS Insights<sup>TM</sup> report, we study the landscape of TBK1 through the lens of the CAS Content Collection<sup>TM</sup> and investigate whether QSAR computer modeling – using chemical structures, the experimental activity of existing chemicals, and mathematical tools to predict the activity of new chemicals — can accelerate the development of effective TBK1 inhibitors.</p><figure class="w-richtext-align-center w-richtext-figure-type-image"><div><img src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66eb135fb4bb9d76205b82e4_66eb1306d7e75c71c7229a51_INSGENENGWHP102219-TBK1-Protein-Kinase-Inhibitors-Insight-Report-fanned%2520image.png" loading="lazy" alt="TBK1 Fanned image"/></div></figure><p> </p></div><a href="https://web.cas.org/marketing/pdf/INSGENENGWHP102219-TBK1-Protein-Kinase-Inhibitors-Insight-Report_A4-Digital.pdf" class="button is-medium w-button">Download the insights report</a><a href="#" class="button w-condition-invisible w-dyn-bind-empty w-button"></a><div class="w-layout-vflex article__post-cta-wrapper"><div class="cta__dark"><div class="cta__dark-content"><h2 class="cta__dark-title">Gain new perspectives for faster progress directly to your inbox.</h2><div class="cta__button-wrapper"><a href="/zh-hans/cas-insights-subscribe" class="button is-medium w-button">Subscribe to CAS Insights</a></div></div><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/655cf3c831d55db466d467e6_long-hex-left__bottom.svg" loading="lazy" width="141.5" alt="" class="cta__dark-accent_bottom-left"/><img src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/655cf3c83233bc880f83e322_long-hex-right__top.svg" loading="lazy" width="145" alt="" class="cta__dark-accent_bottom-right"/></div></div></article></main><aside id="w-node-_2eefa787-b0ef-b4f6-fa25-16633433afc5-33851ef6" class="article__post-sidebar"><div class="w-layout-vflex article__sidebar-signup"><h2 class="article__sidebar-signup-title">Gain new perspectives for faster progress directly to your inbox.</h2><a href="/zh-hans/cas-insights-subscribe" class="button is-medium w-button">Subscribe to CAS Insights</a></div><div class="w-layout-vflex article__sidebar--table-of-contents"><h3 class="heading-style-h4">Article contents</h3><div class="article__sidebar--toc-link-wrapper"><a fs-toc-element="link" href="#" class="article__sidebar--toc-link">Text Link</a><div class="article__sidebar--toc-link-wrapper"><a fs-toc-element="link" href="#" class="article__sidebar--toc-link sub-1-toc">Text Link</a><div class="article__sidebar--toc-link-wrapper"><a fs-toc-element="link" href="#" class="article__sidebar--toc-link sub-2-toc">Text Link</a><div class="article__sidebar--toc-link-wrapper"><a fs-toc-element="link" href="#" class="article__sidebar--toc-link sub-3-toc">Text Link</a></div></div></div></div></div><div class="w-layout-vflex article__related-posts-wrapper"><h2 class="article__sidebar-title">Related CAS Insights</h2><div><div class="w-dyn-list"><div role="list" class="w-dyn-items"><div role="listitem" class="article__sidebar-related-item w-dyn-item"><div itemtype="http://schema.org/Article" itemscope="" id="w-node-a20cb0dd-b9df-6a0b-dbc5-c6732757fde8-2757fde8" class="card"><img src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/668d8bbaa064220eb346c3aa_665630178896a5c734fae00f_GettyImages-1194829395_CAS-Insights-Hero-Image.jpeg" loading="lazy" width="1024" height="576" alt="" property="image" class="card__image"/><div property="articleSection" fs-cmsfilter-field="resource" class="card__eyebrow">Digital R&D</div><div class="card__body"><div class="card__webinar-block"></div><a itemprop="url" href="/zh-hans/resources/cas-insights/scientific-search-engines-why-designing-them-takes-art-plus-science" class="card__title-link w-inline-block"><h2 property="headline" class="card__title">科学搜索引擎：为什么设计它们需要艺术和科学</h2></a><div class="card__date-meta-block"><time property=""datePublished"" datetime="">June 28, 2024</time></div><div class="card__feature-solution--wrapper"></div></div><div class="button-wrapper button-wrapper-full-width"><a href="/zh-hans/resources/cas-insights/scientific-search-engines-why-designing-them-takes-art-plus-science" class="button is-medium w-button">Read article</a></div></div></div><div role="listitem" class="article__sidebar-related-item w-dyn-item"><div itemtype="http://schema.org/Article" itemscope="" id="w-node-a20cb0dd-b9df-6a0b-dbc5-c6732757fde8-2757fde8" class="card"><img class="card__image" src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image.jpg" width="1024" height="576" alt="" sizes="(max-width: 1439px) 33vw, 480px" property="image" loading="lazy" srcset="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image-p-500.webp 500w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image-p-800.webp 800w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image.jpg 1920w"/><div property="articleSection" fs-cmsfilter-field="resource" class="card__eyebrow">Digital R&D</div><div class="card__body"><div class="card__webinar-block"></div><a itemprop="url" href="/zh-hans/resources/cas-insights/emerging-trends-global-biothreat-detection" class="card__title-link w-inline-block"><h2 property="headline" class="card__title">Emerging trends in global biothreat detection</h2></a><div class="card__date-meta-block"><time property=""datePublished"" datetime="">May 3, 2024</time></div><div class="card__feature-solution--wrapper"></div></div><div class="button-wrapper button-wrapper-full-width"><a href="/zh-hans/resources/cas-insights/emerging-trends-global-biothreat-detection" class="button is-medium w-button">Read article</a></div></div></div><div role="listitem" class="article__sidebar-related-item w-dyn-item"><div itemtype="http://schema.org/Article" itemscope="" id="w-node-a20cb0dd-b9df-6a0b-dbc5-c6732757fde8-2757fde8" class="card"><img class="card__image" src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image.webp" width="1024" height="576" alt="" sizes="(max-width: 1439px) 33vw, 480px" property="image" loading="lazy" srcset="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-500.webp 500w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-800.webp 800w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-1080.webp 1080w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-1600.webp 1600w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image.webp 1920w"/><div property="articleSection" fs-cmsfilter-field="resource" class="card__eyebrow">Digital R&D</div><div class="card__body"><div class="card__webinar-block"></div><a itemprop="url" href="/zh-hans/resources/cas-insights/predicting-and-countering-chemical-threats" class="card__title-link w-inline-block"><h2 property="headline" class="card__title">Predicting and countering chemical threats: The strategic role of data-driven technologies</h2></a><div class="card__date-meta-block"><time property=""datePublished"" datetime="">March 12, 2024</time></div><div class="card__feature-solution--wrapper"></div></div><div class="button-wrapper button-wrapper-full-width"><a href="/zh-hans/resources/cas-insights/predicting-and-countering-chemical-threats" class="button is-medium w-button">Read article</a></div></div></div></div></div></div><div class="w-condition-invisible"><div class="w-dyn-list"><div role="list" class="w-dyn-items"><div role="listitem" class="w-dyn-item"><div class="article__related-posts"><div class="w-layout-vflex article__related-post"><div class="w-layout-vflex article__related-post-image-wrapper"><a href="/zh-hans/resources/cas-insights/scientific-search-engines-why-designing-them-takes-art-plus-science" class="insights__related-post-link w-inline-block"><img loading="lazy" width="500" height="282" src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/668d8bbaa064220eb346c3aa_665630178896a5c734fae00f_GettyImages-1194829395_CAS-Insights-Hero-Image.jpeg" alt="科学家在实验室中使用计算机" class="insights__related-post-image"/></a></div><div class="insights__related-post-category_wrapper"><div class="insights__related-post-category">Digital R&D</div><div class="insights__related-post-category">Intellectual Property</div><div class="insights__related-post-category w-condition-invisible w-dyn-bind-empty"></div></div><a href="/zh-hans/resources/cas-insights/scientific-search-engines-why-designing-them-takes-art-plus-science" class="article__related-posts-link-block w-inline-block"><h3 class="insights__related-post-title">科学搜索引擎：为什么设计它们需要艺术和科学</h3></a><div><div class="article__related-posts-publish-date">June 28, 2024</div></div></div></div></div><div role="listitem" class="w-dyn-item"><div class="article__related-posts"><div class="w-layout-vflex article__related-post"><div class="w-layout-vflex article__related-post-image-wrapper"><a href="/zh-hans/resources/cas-insights/emerging-trends-global-biothreat-detection" class="insights__related-post-link w-inline-block"><img loading="lazy" width="500" height="282" src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image.jpg" alt="Human cell and virus cells" sizes="100vw" srcset="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image-p-500.webp 500w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image-p-800.webp 800w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image.jpg 1920w" class="insights__related-post-image"/></a></div><div class="insights__related-post-category_wrapper"><div class="insights__related-post-category">Digital R&D</div><div class="insights__related-post-category w-condition-invisible w-dyn-bind-empty"></div><div class="insights__related-post-category w-condition-invisible w-dyn-bind-empty"></div></div><a href="/zh-hans/resources/cas-insights/emerging-trends-global-biothreat-detection" class="article__related-posts-link-block w-inline-block"><h3 class="insights__related-post-title">Emerging trends in global biothreat detection</h3></a><div><div class="article__related-posts-publish-date">May 3, 2024</div></div></div></div></div><div role="listitem" class="w-dyn-item"><div class="article__related-posts"><div class="w-layout-vflex article__related-post"><div class="w-layout-vflex article__related-post-image-wrapper"><a href="/zh-hans/resources/cas-insights/predicting-and-countering-chemical-threats" class="insights__related-post-link w-inline-block"><img loading="lazy" width="500" height="282" src="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image.webp" alt="Particles data wave" sizes="100vw" srcset="https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-500.webp 500w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-800.webp 800w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-1080.webp 1080w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image-p-1600.webp 1600w, https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image.webp 1920w" class="insights__related-post-image"/></a></div><div class="insights__related-post-category_wrapper"><div class="insights__related-post-category">Digital R&D</div><div class="insights__related-post-category w-condition-invisible w-dyn-bind-empty"></div><div class="insights__related-post-category w-condition-invisible w-dyn-bind-empty"></div></div><a href="/zh-hans/resources/cas-insights/predicting-and-countering-chemical-threats" class="article__related-posts-link-block w-inline-block"><h3 class="insights__related-post-title">Predicting and countering chemical threats: The strategic role of data-driven technologies</h3></a><div><div class="article__related-posts-publish-date">March 12, 2024</div></div></div></div></div></div></div></div></div></aside></div></div><div class="scroll-to-top-wrapper"><a href="#page-anchor" class="button button-scroll w-button">Scroll to top</a></div><footer class="site-footer_component"><section class="section"><div class="container-2-2"><div class="grid-column-5"><div class="site-footer_link-list"><div class="margin-bottom margin-xsmall"><div class="site-footer_heading">解决方案</div></div><a href="/zh-hans/solutions/biofinder-discovery-platform" class="site-footer_link">CAS BioFinder Discovery Platform™</a><a href="/zh-hans/solutions/cas-scifinder-discovery-platform" class="site-footer_link">CAS SciFinder Discovery Platform™</a><a href="/zh-hans/solutions/stn-ip-protection-suite" class="site-footer_link">STN IP Protection Suite™</a><a href="/zh-hans/solutions/cas-custom-services" class="site-footer_link">CAS 定制服务</a><a href="/zh-hans/solutions/other-solutions" class="site-footer_link">其他解决方案</a></div><div class="site-footer_link-list"><div class="margin-bottom margin-xsmall"><div class="site-footer_heading">资源</div></div><a href="/zh-hans/resources/cas-insights" class="site-footer_link">CAS 见解</a><a href="/zh-hans/cas-events" class="site-footer_link">活动</a><a href="/zh-hans/cas-webinars" class="site-footer_link">网络研讨会</a><a href="/zh-hans/resources/white-papers" class="site-footer_link">白皮书</a><a href="/zh-hans/resources/case-studies" class="site-footer_link">案例研究</a><a href="https://commonchemistry.cas.org/" class="site-footer_link">CAS Common Chemistry</a><a href="https://cassi.cas.org/" class="site-footer_link">CAS 来源索引 (CASSI)</a></div><div class="site-footer_link-list"><div class="margin-bottom margin-xsmall"><div class="site-footer_heading">CAS 数据</div></div><a href="/zh-hans/cas-data/cas-registry" class="site-footer_link">CAS REGISTRY®</a><a href="/zh-hans/cas-data/cas-reactions" class="site-footer_link">CAS Reactions</a><a href="/zh-hans/cas-data/cas-references" class="site-footer_link">CAS References</a><a href="/zh-hans/cas-data/cas-patents" class="site-footer_link">CAS Patents</a><a href="/zh-hans/cas-data/cas-commercial-sources" class="site-footer_link">CAS Commercial Sources</a><a href="/zh-hans/cas-data/cas-formulations" class="site-footer_link">CAS Formulations</a></div><div class="site-footer_link-list"><div class="margin-bottom margin-xsmall"><div class="site-footer_heading">关于 CAS</div></div><a href="/zh-hans/about-us" class="site-footer_link">我们的故事</a><a href="/zh-hans/careers" class="site-footer_link">招贤纳士</a><a href="/zh-hans/about/futureleaders" class="site-footer_link">CAS Future Leaders</a><a href="/zh-hans/cas-innovation-incubator" class="site-footer_link">CAS 创新孵化器</a><a href="/zh-hans/press-releases" class="site-footer_link">新闻发布</a></div><div class="site-footer_right-wrapper"><div class="margin-bottom margin-xsmall"><div class="site-footer_heading">CAS 客户中心</div></div><div class="margin-bottom margin-xsmall is-small-mobile"><div class="text-size-small"><a href="mailto:help@cas.org" class="site-footer_link">help@cas.org</a></div><div class="text-size-small"><a href="tel:+1-800-753-4227" class="site-footer_link">800.753.4227（北美）</a></div><div class="text-size-small"><a href="tel:+1-614-447-3731" class="site-footer_link">614.447.3731 (全球)</a></div><div class="text-size-small"><a href="https://goo.gl/maps/y7K2gChT9TDv61SQ6" class="site-footer_link">2540 Olentangy River RoadColumbus, Ohio 43202 U.S.A</a></div></div><a href="/zh-hans/contact" class="button is-medium w-button">联系我们</a></div></div><div class="site-footer_divider"></div><div class="footer_bottom-wrapper"><div class="w-layout-grid footer_legal-list"><div id="w-node-_9015492a-b7f3-be43-cf28-dfe12f081ccc-2f081c75" class="footer10_credit-text">版权所有 © 2024 American Chemical Society</div><a href="/zh-hans/legal" class="site-footer_legal-link">合法</a><a href="/zh-hans/legal/privacy" class="site-footer_legal-link">隐私</a><a href="https://solutions.cas.org/Manage-Preferences" class="site-footer_legal-link">电子邮件偏好</a><a href="https://www.acs.org/accessibility-statement.html" class="site-footer_legal-link">可访问性</a><a id="w-node-a2b696ea-1601-ffae-3b03-3766d928fd0d-2f081c75" class="site-footer_legal-link" href="#">Cookie 偏好</a></div><div class="w-layout-grid footer_social-list"><a href="https://www.facebook.com/CAS" target="_blank" class="site-footer_social-link w-inline-block"><div class="icon-embed-xsmall w-embed"><svg width="100%" height="100%" viewBox="0 0 24 24" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M22 12.0611C22 6.50451 17.5229 2 12 2C6.47715 2 2 6.50451 2 12.0611C2 17.0828 5.65684 21.2452 10.4375 22V14.9694H7.89844V12.0611H10.4375V9.84452C10.4375 7.32296 11.9305 5.93012 14.2146 5.93012C15.3088 5.93012 16.4531 6.12663 16.4531 6.12663V8.60261H15.1922C13.95 8.60261 13.5625 9.37822 13.5625 10.1739V12.0611H16.3359L15.8926 14.9694H13.5625V22C18.3432 21.2452 22 17.083 22 12.0611Z" fill="CurrentColor"/> </svg></div></a><a href="https://www.twitter.com/CASChemistry" target="_blank" class="site-footer_social-link w-inline-block"><div class="icon-embed-xsmall w-embed"><svg width="100%" height="100%" viewBox="0 0 24 24" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M17.1761 4H19.9362L13.9061 10.7774L21 20H15.4456L11.0951 14.4066L6.11723 20H3.35544L9.80517 12.7508L3 4H8.69545L12.6279 9.11262L17.1761 4ZM16.2073 18.3754H17.7368L7.86441 5.53928H6.2232L16.2073 18.3754Z" fill="CurrentColor"/> </svg></div></a><a href="https://www.linkedin.com/company/cas" target="_blank" class="site-footer_social-link w-inline-block"><div class="icon-embed-xsmall w-embed"><svg width="100%" height="100%" viewBox="0 0 24 24" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M4.5 3C3.67157 3 3 3.67157 3 4.5V19.5C3 20.3284 3.67157 21 4.5 21H19.5C20.3284 21 21 20.3284 21 19.5V4.5C21 3.67157 20.3284 3 19.5 3H4.5ZM8.52076 7.00272C8.52639 7.95897 7.81061 8.54819 6.96123 8.54397C6.16107 8.53975 5.46357 7.90272 5.46779 7.00413C5.47201 6.15897 6.13998 5.47975 7.00764 5.49944C7.88795 5.51913 8.52639 6.1646 8.52076 7.00272ZM12.2797 9.76176H9.75971H9.7583V18.3216H12.4217V18.1219C12.4217 17.742 12.4214 17.362 12.4211 16.9819V16.9818V16.9816V16.9815V16.9812C12.4203 15.9674 12.4194 14.9532 12.4246 13.9397C12.426 13.6936 12.4372 13.4377 12.5005 13.2028C12.7381 12.3253 13.5271 11.7586 14.4074 11.8979C14.9727 11.9864 15.3467 12.3141 15.5042 12.8471C15.6013 13.1803 15.6449 13.5389 15.6491 13.8863C15.6605 14.9339 15.6589 15.9815 15.6573 17.0292V17.0294C15.6567 17.3992 15.6561 17.769 15.6561 18.1388V18.3202H18.328V18.1149C18.328 17.6629 18.3278 17.211 18.3275 16.7591V16.759V16.7588C18.327 15.6293 18.3264 14.5001 18.3294 13.3702C18.3308 12.8597 18.276 12.3563 18.1508 11.8627C17.9638 11.1286 17.5771 10.5211 16.9485 10.0824C16.5027 9.77019 16.0133 9.5691 15.4663 9.5466C15.404 9.54401 15.3412 9.54062 15.2781 9.53721L15.2781 9.53721L15.2781 9.53721C14.9984 9.52209 14.7141 9.50673 14.4467 9.56066C13.6817 9.71394 13.0096 10.0641 12.5019 10.6814C12.4429 10.7522 12.3852 10.8241 12.2991 10.9314L12.2991 10.9315L12.2797 10.9557V9.76176ZM5.68164 18.3244H8.33242V9.76733H5.68164V18.3244Z" fill="CurrentColor"/> </svg></div></a><a href="https://www.youtube.com/user/ChemAbstractsService/featured" target="_blank" class="site-footer_social-link w-inline-block"><div class="icon-embed-xsmall w-embed"><svg width="100%" height="100%" viewBox="0 0 24 24" fill="none" xmlns="http://www.w3.org/2000/svg"> <path fill-rule="evenodd" clip-rule="evenodd" d="M20.5686 4.77345C21.5163 5.02692 22.2555 5.76903 22.5118 6.71673C23.1821 9.42042 23.1385 14.5321 22.5259 17.278C22.2724 18.2257 21.5303 18.965 20.5826 19.2213C17.9071 19.8831 5.92356 19.8015 3.40294 19.2213C2.45524 18.9678 1.71595 18.2257 1.45966 17.278C0.827391 14.7011 0.871044 9.25144 1.44558 6.73081C1.69905 5.78311 2.44116 5.04382 3.38886 4.78753C6.96561 4.0412 19.2956 4.282 20.5686 4.77345ZM9.86682 8.70227L15.6122 11.9974L9.86682 15.2925V8.70227Z" fill="CurrentColor"/> </svg></div></a></div></div></div></section></footer></div><script src="https://d3e54v103j8qbb.cloudfront.net/js/jquery-3.5.1.min.dc5e7f18c8.js?site=650861f00f97fe8153979335" type="text/javascript" integrity="sha256-9/aliU8dGd2tb6OSsuzixeV4y/faTqgFtohetphbbj0=" crossorigin="anonymous"></script><script src="https://cdn.prod.website-files.com/650861f00f97fe8153979335/js/cas-org.196e15fb.24a0141b2aa72f7b.js" type="text/javascript"></script><script>var UTMTracker=function(){function t(t){void 0===t&&(t={}),this.cookieExpDays=t.cookieExpDays||90,this.cookieName="urlParameters",this.requiredParams=["utm_source","utm_medium","utm_campaign"],this.optionalParams=["utm_term","utm_content"],this.adPlatformParams=["gclid","msclkid","fbclid"]}return t.prototype.init=function(){"undefined"!=typeof Osano&&Osano.cm.getConsent("analytics")?(this.saveParamsCookie(),this.pushToForms()):"undefined"!=typeof Osano&&document.addEventListener("osano-cm-consent-changed",function(t){!0===t.detail.analytics&&(this.saveParamsCookie(),this.pushToForms())}.bind(this))},t.prototype.getCookieExpiration=function(){var t=new Date;return t.setDate(t.getDate()+this.cookieExpDays),t.toUTCString()},t.prototype.sanitizeValue=function(t){try{return decodeURIComponent(t).replace(/[<>{}]/g,"").substring(0,255)}catch(t){return console.error("Error sanitizing value:",t),""}},t.prototype.parseURLParams=function(){var t={};try{var e=new URLSearchParams(window.location.search);this.requiredParams.forEach(function(r){var a=e.get(r);a&&(t[r]=this.sanitizeValue(a))}.bind(this)),this.optionalParams.forEach(function(r){var a=e.get(r);a&&(t[r]=this.sanitizeValue(a))}.bind(this)),this.adPlatformParams.forEach(function(r){var a=e.get(r);a&&(t[r]=this.sanitizeValue(a),t.lta=this.getAttributionSource(r))}.bind(this)),!t.lta&&document.referrer&&(t.lta=new URL(document.referrer).hostname)}catch(t){console.error("Error parsing URL parameters:",t)}return t},t.prototype.getAttributionSource=function(t){return{gclid:"Google Ads",msclkid:"Bing Ads",fbclid:"Facebook Ads"}[t]||"Unknown"},t.prototype.saveParamsCookie=function(){var t=this.parseURLParams();if(Object.keys(t).length>0)try{var e=JSON.stringify(t);document.cookie=this.cookieName+"="+e+"; expires="+this.getCookieExpiration()+"; path=/; SameSite=Strict"}catch(t){console.error("Error saving cookie:",t)}},t.prototype.getSavedParams=function(){try{var t=document.cookie.split("; ").find(function(t){return t.startsWith(this.cookieName+"=")}.bind(this));if(t){var e=t.split("=")[1];return JSON.parse(e)}}catch(t){console.error("Error reading cookie:",t)}return null},t.prototype.pushToForms=function(){var t=this.getSavedParams();if(t){var e={utm_source:"hiddenCampaignsource",utm_medium:"hiddenCampaignmedium",utm_campaign:"hiddenCampaignname",utm_content:"hiddenCampaigncontent",utm_term:"utm_term",lta:"last_touch_attribution"};Object.entries(e).forEach(function(e){var r=e[0],a=e[1];if(t[r]){document.querySelectorAll("."+a+' input[type="text"]').forEach(function(e){e.value=t[r]})}})}},t}(); document.addEventListener("DOMContentLoaded",function(){(new UTMTracker({cookieExpDays:90})).init()}); </script><script type="text/javascript" src="/_Incapsula_Resource?SWJIYLWA=719d34d31c8e3a6e6fffd425f7e032f3&ns=2&cb=261456613" async></script></body></html>