CINXE.COM

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and Gene Therapy Research</h1> <p>Cell and Gene therapies are a rapidly expanding area of research, with wide reaching therapeutic applications. Cell therapy refers to the introduction of cellular materials to treat a disease while gene therapy refers to the delivery of nucleic acid into cells to treat a disease.</p> <p>Find out more about Bio-techne's GMP Capabilities and how we can support your <a href='https://www.bio-techne.com/gmp-products/gmp-capabilities' class='a___link-external' target='_blank'>Cell and Gene Therapy</a> development program by visiting <a href='https://www.bio-techne.com/gmp-products/gmp-capabilities' class='a___link-external' target='_blank'>bio-techne.com</a>.</p> <div class="tabbed_content"> <div class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="products" id="pharm_tabs_products"> <span>Research Areas</span></div> <div class="tab tab_4" data-tab="4" data-tabname="literature" id="pharm_tabs_literature"><span>Literature (4)</span> </div> </div> <div class="tab_content tab_1 tab_open" data-tab="1"> <div class="pharm_sub_cats"><h3>Cell and Gene Therapy Research Product Areas</h3><ul class="tile_column_1"><li><a href="/research-area/gene-therapy" title="Browse products for Gene Therapy">Gene Therapy</a></li><li><a href="/research-area/immune-cell-therapy" title="Browse products for Immune Cell Therapy">Immune Cell Therapy</a></li></ul><ul class="tile_column_2"><li><a href="/research-area/stem-cell-therapy" title="Browse products for Stem Cell Therapy">Stem Cell Therapy</a></li></ul></div> </div> <div class="tab_content tab_2" data-tab="2"> </div> <div class="tab_content tab_3" data-tab="3"> </div> <div class="tab_content tab_4" data-tab="4"> <h3>Literature for Cell and Gene Therapy Research</h3><p>Tocris offers the following scientific literature for Cell and Gene Therapy Research to showcase our products. We invite you to request* or download your copy today!</p><p class="small">*Please note that Tocris will only send literature to established scientific business / institute addresses.</p><hr/><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/product-guides/fullsize/683696.jpg?v=4" data-toggle="lightbox" data-title="Stem Cell Research Product Guide" data-footer="<a href='/literature/literature-request/683696' rel='nofollow' title='Request copy of the Stem Cell'>Request copy</a> or <a href='/literature/literature-request/p683696' rel='nofollow' title='Request PDF of the Stem Cell'>Request PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/product-guides/regular/683696.jpg?v=4" alt="Stem Cell Research Product Guide" class="img-fluid"></a></div> <h4>Stem Cell Research Product Guide</h4> <p>This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:</p> <ul class='bullet_list'> <li>Self-renewal and Maintenance</li> <li>Differentiation</li> <li>Reprogramming</li> <li>Organoid Generation</li> <li>GMP and Ancillary Material Grade Products </li> </ul> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/683696" rel="nofollow" title="Request copy of the Stem Cell Research Product Guide">Request copy</a> </li><li> <a class="btn btn-quinary request-pdf" href="/literature/literature-request/p683696" rel="nofollow" title="Request PDF of the Stem Cell Research Product Guide">Request PDF<div class="lit_request_pdf"></div></a> </li> <li><a class="btn btn-quinary" href="/literature/product-guides" title="View all Product Guides & Listings">View all Product Guides & Listings</a></li> </ul> </div></div><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/reviews/fullsize/298320.jpg?v=2" data-toggle="lightbox" data-title="Stem Cells Scientific Review" data-footer="<a href='/literature/literature-request/298320' rel='nofollow' title='Request copy of the Stem Cells'>Request copy</a> or <a href='/literature/literature-request/p298320' rel='nofollow' title='Request PDF of the Stem Cells'>Request PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/reviews/regular/298320.jpg?v=2" alt="Stem Cells Scientific Review" class="img-fluid"></a></div> <h4>Stem Cells Scientific Review</h4> <p>Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.</p> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/298320" rel="nofollow" title="Request copy of the Stem Cells Scientific Review">Request copy</a> </li><li> <a class="btn btn-quinary request-pdf" href="/literature/literature-request/p298320" rel="nofollow" title="Request PDF of the Stem Cells Scientific Review">Request PDF<div class="lit_request_pdf"></div></a> </li> <li><a class="btn btn-quinary" href="/literature/scientific-reviews" title="View all Scientific Reviews">View all Scientific Reviews</a></li> </ul> </div></div><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/630620.jpg" data-toggle="lightbox" data-title="Stem Cell Workflow Poster" data-footer="<a href='/literature/literature-request/630620' rel='nofollow' title='Request copy of the Stem Cell Workflow'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf' download='https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf' rel='nofollow' title='Download PDF of the Stem Cell Workflow' data-title='Stem Cell Workflow Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/630620.jpg" alt="Stem Cell Workflow Poster" class="img-fluid"></a></div> <h4>Stem Cell Workflow Poster</h4> <p>Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.</p> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/630620" rel="nofollow" title="Request copy of the Stem Cell Workflow Poster">Request copy</a> </li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cell Workflow Poster" data-title="Stem Cell Workflow Poster">Download PDF<div class="lit_pdf"></div></a></li> <li><a class="btn btn-quinary" href="/literature/life-science-posters" title="View all Life Science Posters">View all Life Science Posters</a></li> </ul> </div></div><div class="lit_item"> <div class="lit_content"> <div class="lit_image"> <a href="https://resources.tocris.com/images/literature/posters/fullsize/571184.jpg?v=2" data-toggle="lightbox" data-title="Stem Cells Poster" data-footer="<a href='/literature/literature-request/571184' rel='nofollow' title='Request copy of the Stem Cells'>Request copy</a> or <a class=' pdf-download' href='https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf' download='https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf' rel='nofollow' title='Download PDF of the Stem Cells' data-title='Stem Cells Poster'>Download PDF</a> today"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/571184.jpg?v=2" alt="Stem Cells Poster" class="img-fluid"></a></div> <h4>Stem Cells Poster</h4> <p>Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.</p> <ul class="pb_lit_buttons"><li> <a class="btn btn-quinary" href="/literature/literature-request/571184" rel="nofollow" title="Request copy of the Stem Cells Poster">Request copy</a> </li> <li><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cells Poster" data-title="Stem Cells Poster">Download PDF<div class="lit_pdf"></div></a></li> <li><a class="btn btn-quinary" href="/literature/life-science-posters" title="View all Life Science Posters">View all Life Science Posters</a></li> </ul> </div></div> </div> <div class="tab_content tab_5" data-tab="5"> </div> <div class="tab_content tab_6" data-tab="6"> </div> </div> </div> <div id="sidebar" class="col-xs-12 col-sm-4 col-md-3 col-lg-3 col-xl-3"> <div class="resources_sidebar_container"> <div class="fp_four_box"> <div class="fp_box_wrapper"><h3>Featured New Products</h3> <div class="fp_featured_product"><a href="/products/vu-0542270_8151">8151 | VU 0542270</a><br /> Selective inhibitor of K<sub>ir</sub>6.1 K<sub>ATP</sub> channels</div> <div class="fp_featured_product"><a href="/products/rna-imaging-probe-1c_8813">8813 | RNA Imaging Probe 1c</a><br /> Fluorogenic RNA imaging probe</div> <div class="fp_featured_product"><a href="/products/lsn-3318839_7959">7959 | LSN 3318839</a><br /> Glucagon-like peptide-1 receptor <br />(GLP1-R) positive allosteric modulator</div> <div class="fp_featured_product"><a href="/products/chir-99021-in-solution_8170">8170 | CHIR 99021 in solution</a><br /> Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO</div> <div class="fp_featured_product"><a href="/products/bi-3231_8039">8039 | BI 3231</a><br /> Potent and selective hydroxysteroid 17尾 dehydrogenase 13 (HSD17B13) inhibitor</div> </div> </div> </div> <div class="distributor_region"></div> <div class="widget"> <div class="widget_title">Literature in this Area</div> <div class="widget_content carousel slide" id="ds_literature_scroller" data-ride="carousel" data-interval="8000">  <div class="carousel-inner"><div class="item active"><div class="highlight">Stem Cell Research Product Guide</div> <a href="/literature/product-guides/stem-cell"><img loading="lazy" src="https://resources.tocris.com/images/literature/product-guides/regular/683696.jpg?v=4" alt="Stem Cell Research Product Guide"></a><p class="small">Our guide highlights the use of small molecules in stem cell research and cell therapy and lists relevant products.</p><a class="btn btn-quinary" href="/literature/literature-request/683696" rel="nofollow" title="Request copy of the Stem Cell Research Product Guide">Request copy</a><a class="btn btn-quinary request-pdf" href="/literature/literature-request/p683696" rel="nofollow" title="Request PDF of the Stem Cell Research Product Guide">Request PDF<div class="lit_request_pdf"></div></a></div><div class="item"><div class="highlight">Stem Cells Scientific Review</div> <a href="/literature/scientific-reviews/stem-cells"><img loading="lazy" src="https://resources.tocris.com/images/literature/reviews/regular/298320.jpg?v=2" alt="Stem Cells Scientific Review"></a><p class="small">Our Stem Cells review gives an overview of the use of small molecules in the control of stem cell growth & differentiation and somatic cell reprogramming.</p><a class="btn btn-quinary" href="/literature/literature-request/298320" rel="nofollow" title="Request copy of the Stem Cells Scientific Review">Request copy</a><a class="btn btn-quinary request-pdf" href="/literature/literature-request/p298320" rel="nofollow" title="Request PDF of the Stem Cells Scientific Review">Request PDF<div class="lit_request_pdf"></div></a></div><div class="item"><div class="highlight">Stem Cell Workflow Life Science Poster</div> <a href="/literature/life-science-posters/stem-cell-workflow"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/630620.jpg" alt="Stem Cell Workflow Poster"></a><p class="small">Developed in-house, this poster summarizes how small molecules have been used in protocols across the stem cell workflow.</p><a class="btn btn-quinary" href="/literature/literature-request/630620" rel="nofollow" title="Request copy of the Stem Cell Workflow Poster">Request copy</a><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cell Workflow Poster" data-title="Stem Cell Workflow Poster">Download PDF<div class="lit_pdf"></div></a></div><div class="item"><div class="highlight">Stem Cells Life Science Poster</div> <a href="/literature/life-science-posters/stem-cells"><img loading="lazy" src="https://resources.tocris.com/images/literature/posters/regular/571184.jpg?v=2" alt="Stem Cells Poster"></a><p class="small">Written by Rebecca Quelch and Stefan Przyborski, this poster summarizes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and potential uses.</p><a class="btn btn-quinary" href="/literature/literature-request/571184" rel="nofollow" title="Request copy of the Stem Cells Poster">Request copy</a><a class="btn btn-quinary pdf-download" href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" rel="nofollow" target="_blank" title="Download PDF of the Stem Cells Poster" data-title="Stem Cells Poster">Download PDF<div class="lit_pdf"></div></a></div></div>  <a class="left carousel-control" 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