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Cell Therapy | BioAgilytix
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-webkit-transition-property: border-color; -o-transition-property: border-color; transition-property: border-color; } /* Style new checked item */ ul.inputs-list.multi-container li.hs-form-checkbox label span::after, .hs-form-booleancheckbox-display span::after { content: ""; border: 2px solid #d9d9d9; border-radius: 3px; height: 20px; left: 0px; position: absolute; top: 0px; width: 20px; background: #fff; z-index: 0; display: block; transition-property: background-color, border-color, -webkit-box-shadow; -o-transition-property: background-color, border-color, box-shadow; transition-property: background-color, border-color, box-shadow; transition-property: background-color, border-color, box-shadow, -webkit-box-shadow; } /* Show when checked */ ul.inputs-list.multi-container li.hs-form-checkbox label input:checked + span::after, .hs-form-booleancheckbox-display input:checked + span::after, ul.inputs-list.multi-container li.hs-form-checkbox label input:checked + span::before, .hs-form-booleancheckbox-display input:checked + span::before{ opacity: 1; } .hs-form-booleancheckbox-display input:checked+label:after, .hs-form-booleancheckbox-display input:checked+label:after { background: #fff; border-color: #157479; } /* Style when focused */ ul.inputs-list.multi-container li.hs-form-checkbox label input:focus + span::after, .hs-form-booleancheckbox-display input:focus + span::after { outline: 3px solid transparent; /* For Windows high contrast mode. */ box-shadow: 0 0 .3125rem rgba(0, 0, 0, .3); border-color: #157479; } .hs_contact_country{ clear: both; } .hs-button { border-radius: 65px !important; font-size: 14px; line-height: 1.3; letter-spacing: 1.12px; font-family: "Roboto Slab", helvetica, arial, sans-serif; font-weight: 700 !important; padding: 19px 23px !important; border: 2px solid; display: inline-block; text-decoration: none; text-transform: uppercase; -webkit-appearance: none !important; -moz-appearance: none !important; appearance: none !important; } .hbspt-form textarea{max-width: 100% !important; height: 186px !important; resize: none;} .hbspt-form textarea:focus{border: 1px solid #74cbc8 !important;} .hs-fieldtype-textarea .invalid.error{border: 2px solid #E74949 !important;} .hbspt-form fieldset{max-width: 100% !important; margin-bottom: 60px;} .hbspt-form .field {margin-bottom: 27px} .hs_recaptcha{ margin-top: 23px !important; margin-bottom: 27px !important; } .hs-button, .hs-form-field input[type=text], .hs-form-field input[type=email], .hs-form-field input[type=phone], .hs-form-field input[type=number], .hs-form-field input[type=tel], .hs-form-field input[type=date], .hs-form-field textarea { appearance: none; -webkit-appearance: none; -moz-appearance: none; } .hs-default-font-element, .hs-main-font-element { font-family: "Roboto Slab", helvetica, arial, sans-serif; } .hbspt-form .hs-button { white-space: pre-wrap } .hbspt-form .hs-richtext { word-break: break-word } .hbspt-form.submitted-message { overflow: auto } .hbspt-form fieldset.form-columns-1 .hs-input { width: 95% } .hbspt-form fieldset.form-columns-1 .input { margin-right: 0px !important } .hbspt-form fieldset.form-columns-1 input[type=checkbox], .hbspt-form fieldset.form-columns-1 input[type=radio] { width: auto } .hbspt-form fieldset.form-columns-2 .hs-form-field { width: 50%; float: left } .hbspt-form fieldset.form-columns-2 .input { margin-right: 0px !important; } .hbspt-form fieldset.form-columns-3 .hs-form-field { width: 32.7%; float: left } .hbspt-form fieldset.form-columns-3 .input { margin-right: 8px } .hbspt-form label.hs-hidden { visibility: hidden } .hbspt-form .hs-field-desc { width: 100% } .hs-custom-style .hs-input, .hs-custom-style fieldset { max-width: 100% } .hs-custom-style>div.form-columns-3 .hs-form-field, .hs-custom-style fieldset.form-columns-3 .hs-form-field { width: 33.3% } .hs-custom-style>div>div:last-of-type .hs-input:not([type=checkbox]):not([type=radio]), .hs-custom-style fieldset>div:last-of-type .hs-input:not([type=checkbox]):not([type=radio]) { width: 100%; max-width: 100% } .hs-custom-style>div input:not([type=image]):not([type=submit]):not([type=button]):not([type=radio]):not([type=checkbox]):not([type=file]), .hs-custom-style fieldset input:not([type=image]):not([type=submit]):not([type=button]):not([type=radio]):not([type=checkbox]):not([type=file]) { box-sizing: border-box; padding: 0 15px; min-height: 27px } .hs-custom-style>div textarea, .hs-custom-style fieldset textarea { padding: 10px 15px } .hs-custom-style .hs-dependent-field>div .hs-input:not([type=checkbox]):not([type=radio]) { width: 100% } .legal-consent-container .field.hs-form-field { margin-bottom: 8px } .legal-consent-container .hs-field-desc.checkbox-desc { margin: -12px 0 0 21px } .legal-consent-container .hs-form-booleancheckbox-display input { float: left } .legal-consent-container .hs-form-booleancheckbox-display>span { display: block !important; margin-left: 30px !important; } .legal-consent-container .hs-form-booleancheckbox-display p { margin: 0; display: inline } .legal-consent-container .hs-error-msgs label { color: #f2545b } .legal-consent-container~.hs_recaptcha { margin-top: 18px } .cookie-reset-container { font-size: 14px; margin-bottom: 10px; text-align: right } #hs-outer-captcha-target, #hs-outer-captcha-target * { display: none; height: 0; width: 0 } .hubspot-link__container { font-size: 14px; padding-bottom: 40px; position: relative; color: #9fa0a2; font-family: "Roboto Slab", helvetica, arial, sans-serif; } .hubspot-link-text { color: #00a4bd; font-weight: 400 } .hubspot-link__container.sproket { color: #9fa0a2 } .hubspot-link { color: #9fa0a2 } .hubspot-link, .hubspot-link:hover { text-decoration: none } .hubspot-link:hover .hubspot-link-text { text-decoration: underline } .hubspot-link__icon { margin-bottom: -1px; margin-right: 5px } .hubspot-link__container.sproket .hubspot-link__icon { width: 30px; margin-right: 0; float: left; margin-top: -9px; margin-left: -5px } .hubspot_signup_form .hs_email{margin-bottom: 0px !important; width: 80% !important; float: left !important;} .hubspot_signup_form .hs_submit{width: 20% !important; float: left !important; } .hubspot_signup_form .hs-button{padding: 12.5px 15px !important;} .hubspot_signup_form .hs_email label{display: none !important;} .hubspot_signup_form ul.no-list{position: absolute !important; top: 48px !important;} .hubspot_signup_form {position: relative !important;} .hubspot_signup_form .submitted-message{color: #ab8940 !important; font-size: 22px !important; } .hubspot_white .hbspt-form label, .hubspot_white .hs-form-required { color: #fff; } .hubspot_white .hs-input, .hubspot_white ul.inputs-list.multi-container li.hs-form-checkbox label span::before, .hubspot_white .hs-form-booleancheckbox-display span::before{ background-color: #fff !important; } .hubspot_white .hs_submit { text-align: center; } .hubspot_white .hs-form select.is-placeholder { opacity: 1; } .hubspot_white ul.inputs-list.multi-container li.hs-form-checkbox label span::after, .hubspot_white .hs-form-booleancheckbox-display span::after { border-color: #3f4852; } input[type=submit].hs-button.primary.large{ color: #fff; background: #00181e; border-color: #00181e !important; } input[type=submit].hs-button.primary.large:hover { background: #74cbc8 !important; border-color: #74cbc8 !important; } /***/ .hbspt-form .hs-input[type=checkbox]{ cursor: pointer; } .hs-form-booleancheckbox-display input:checked + span::after{ background: #fff; border-color: #157479; } .hbspt-form .form-columns-2 { display: flex; flex-flow: row wrap; -webkit-box-direction: normal; } .hbspt-form .hs_firstname { flex: 1; -webkit-box-flex: 1; } .hbspt-form .hs_submit{ margin-top: 60px; } .newsletter-form .hs_submit{margin-top: 45px;} .newsletter-form form .gfield_consent_description { border: none !important; } /*New Landing page*/ .landing-middle-section{ padding-right: 0px !important; } .left-col{max-width:93%} .left-col-para{padding-right:30px;} .left-col video{border-radius:4px;} /* Kit asssesment */ .kits_form_col .hbspt-form .hs-input[type=checkbox] { height: 20px !important; width: 20px !important; } .kits_form_col {padding-bottom: 45px;} .hs-richtext h4 {margin-bottom: 15px !important;} .kits_form_col label.hs-form-checkbox-display {margin-bottom: 15px;} .kits_form_col .hbspt-form li.hs-form-checkbox label span{ margin-left: 0px !important; padding-left: 31px; } .hbspt-form label.hs-form-radio-display { position: relative; padding: 4px 31px; } .hbspt-form .hs-form-radio-display span, .hbspt-form .hs-form-checkbox-display span { position: relative; cursor: pointer; font-size: 15px; font-weight: 300; } .hbspt-form .hs-input[type=radio] { position: absolute; left: 0; z-index: 2; width: 20px !important; height: 20px !important; outline: none; cursor: pointer; background-color: transparent !important; border-radius: 50%; } .hbspt-form .hs_protocol_synopsis_upload .input{position: relative;} .hbspt-form input[type="file"]::-webkit-file-upload-button { cursor: pointer; background-color: #157479; padding: 10px 20px !important; border: 1px solid #157479; border-top-left-radius: 0px; border-bottom-left-radius: 0px; border-top-right-radius: 6px; border-bottom-right-radius: 6px; color: #fff; position: absolute; top: 0; bottom: 0; right: 0; } .hbspt-form input[type="file"] { cursor: pointer; padding: 10px 20px !important; position: relative; top: 0; bottom: 0; right: 0; } /*Form Responsive CSS*/ @media only screen and (min-width: 1024px) and (max-width: 1366px){ .hs_email, .hs_contact_country { clear: both; } } @media only screen and (min-width: 992px) and (max-width: 1024px){ .hs_email, .hs_contact_country { clear: both; } } @media (min-width: 640px) and (max-width: 1120px) { .hbspt-form h1{font-size: 36px !important;} } @media screen and (min-width: 1120px) { .hbspt-form h1{font-size: 45px !important;margin-bottom: 17px !important;} .hbspt-form .gform_heading p{font-size: 17px !important;} } @media only screen and (min-width: 768px) and (max-width: 992px){ .hs_email, .hs_contact_country{ clear: both; } } @media (min-width: 767px) and (max-width: 1024px) { body .hubspot_signup_form .hs_email{width: 66% !important; float: left !important;} } @media screen and (max-width: 992px){ .assay-kit-hbspt-form .fl-col { width: 100%; } } @media screen and (max-width:812px){ .assay-kit-hbspt-form .fl-col { max-width: 100%; } .hbspt-form .hs-fieldtype-select .input:before{ right: 20px !important; } } @media screen and (max-width: 767px){ .hs_submit .actions{padding-top: 0px !important; margin-top: 0px !important;} body .hbspt-form fieldset.form-columns-2 .input {margin-right: 0px !important;} body fieldset.form-columns-3 .input{margin-right: 0px !important;} .hs-form-field .hs-input { width: 100% !important; } .hs-fieldtype-textarea .input{margin-right: 0px !important;} .hs_firstname, .hs_phone, .hs_development_area{ width: 100% !important; } } @media screen and (min-width: 640px){ .hbspt-form .hs_firstname, .kits_form_col .hs_email{ padding-right: 10px; } .hbspt-form .hs-lastname, .kits_form_col .hs_confirm_email{ padding-left: 10px; } .kits_form_col {padding-bottom: 108px;} .hs-richtext h4 {margin-bottom: 30px !important;} .kits_form_col label.hs-form-checkbox-display {margin-bottom: 20px;} } @media screen and (max-width: 640px){ .hbspt-form h1{font-size: 32px !important;} .hbspt-form .gform_heading p{font-size: 16px !important;} .hbspt-form .form-columns-2 .field{ -webkit-box-flex: 0; -ms-flex: 0 0 100%; flex: 0 0 100%; margin-bottom: .5rem; padding-left: 0; } } @media screen and (max-width: 540px){ .event-hero-section > div{ justify-items: flex-start !important; } } @media screen and (max-width: 414px){ body .hubspot_signup_form .hs_email {width: 66% !important;} body .hubspot_signup_form ul.no-list{top: 65px !important;} } @media screen and (max-width: 320px){ body .hubspot_signup_form .hs_email {width: 61% !important;} }</style> <style type="text/css">.about-presenter-section{display:none;} .space-hero-section{margin-bottom:0px !important;} .partner_bioAgilytix {padding-right: 2.5rem !important;} @media screen and (max-width: 540px){ .event-hero-section > div{ justify-items: flex-start !important; } }</style> <style type="text/css">/* Add your CSS code here. 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class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/solutions/">Solutions</a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/solutions/modalities/">Modalities</a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/solutions/modalities/atmp-bioanalysis/">Advanced Therapies (ATMP)</a></span> <span class="breadcrumb-separator"></span> <span class="breadcrumb_last" aria-current="page">Cell Therapy</span></span></div></div></section><div class="wp-block-group alignwide is-layout-constrained wp-container-core-group-is-layout-1 wp-block-group-is-layout-constrained"><p class="has-text-align-center has-large-font-size">Cell Therapy products are a novel approach to therapeutic intervention which use living cells to treat diseases and conditions. Bioanalytical support strategies for this modality are continuing to evolve as we gain an improved understanding of their unique considerations and as new regulatory guidelines are released around this novel drug modality. </p></div><div class="wp-block-emagine-background alignfull has-gray-xxl-background-color em-pt--xl em-pb--xl em-mb--none"><picture><source data-srcset="https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-640x1137.jpg" media="(max-width: 640px)"/><source data-srcset="https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-1120x840.jpg" media="(max-width: 1120px)"/><img fetchpriority="high" decoding="async" width="2000" height="1125" class="wp-block-emagine-background__media wp-image-6644" alt="" src="https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-2000x1125.jpg" style="object-position:0% 49%" srcset="https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-2000x1125.jpg 2000w, https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-1380x776.jpg 1380w, https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-1120x630.jpg 1120w, https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-850x478.jpg 850w, https://www.bioagilytix.com/wp-content/uploads/2024/05/option1_bg-640x360.jpg 640w" sizes="(max-width: 2000px) 100vw, 2000px" /></picture><div class="wp-block-emagine-background__content"><div class="wp-block-emagine-background__content-inner"><div class="wp-block-emagine-grid alignwide wp-block-emagine-grid--halves"><div class="wp-block-emagine-grid__inner em-grid-2_sm-1-equalHeight-left"><div class="wp-block-emagine-column em-col"><h2 class="h2 em-mt--xs" id="gene-therapy-role"><strong>BioAgilytix鈥檚 Cell Therapy Experience</strong></h2><p class="">BioAgilytix has significant scientific expertise and resources for supporting cell therapy products. As of 2023, BioAgilytix has partnered with our clients to support bioanalytical testing for over 80 individual cell therapy programs, including two that have received FDA-approval. We have expertise with a variety of cell therapy programs including:</p><ul class="wp-block-list"><li class=""><a href="https://www.bioagilytix.com/solutions/modalities/atmp-bioanalysis/car-t-cell-therapies/">Chimeric Antigen Receptor T Cell (CAR-T)</a></li><li class="">Chimeric Antigen Receptor NK Cell (CAR-NK) </li><li class="">Tumor-Infiltrating Lymphocyte (TIL) Therapy</li><li class="">Modified B-Cell Therapy</li><li class="">Other modified immune or blood cell types</li></ul></div></div></div></div></div></div><div id="block_aa2212f723f7853779a5babfb59286bc" class="wp-block em-media-content em-mt--none em-mb--none alignfull"><div class="em-media-content__inner em-media-content__inner--media-right has-none-background-color em-media-content__inner--content-has-padding"><div class="em-media-content__media em-media-content__media--right"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2024/05/iStock-1380451602-1254x776.jpg" alt="" class="object-fit--cover" srcset="" width="1254" height="776"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%201254%20776%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2024/05/iStock-1380451602-1254x776.jpg" alt="" class="lazyload object-fit--cover" data-srcset="" width="1254" height="776"></div><div class="em-media-content__content em-media-content__content--left em-media-content__content--add-padding"><h2 class="h2 em-mt--xs" id="gene-services"><strong>Bioanalytical Assay Services for Cell Therapy Programs </strong></h2><p class="">Our scientific teams design and implement analytical methods in support of cell therapy programs with the appropriate level of regulatory oversight from nonregulated to GxP compliant methods for <a href="https://www.bioagilytix.com/solutions/phases/preclinical-research-drug-development/">preclinical </a>and <a href="https://www.bioagilytix.com/solutions/phases/clinical-drug-development-process/">clinical</a> testing. Some of the services commonly provided for our cell therapy clients are:</p><ul class="wp-block-list"><li class="">Nonclinical Biodistribution <a href="https://www.bioagilytix.com/techniques/instrumentation/qpcr-ddpcr-assay/">(PCR)</a></li><li class="">Pharmacokinetics/Persistence (Flow cytometry or PCR)</li><li class="">Anti-CAR Antibody Detection (ADA or NAb)</li><li class="">Anti-Cas9 Antibody Detection</li><li class="">Replication Competent Lentivirus (RCL; PCR-based) </li><li class="">Cellular Immunogenicity (<a href="https://www.bioagilytix.com/techniques/instrumentation/elispot-assay/">ELISpot</a> and/or <a href="https://www.bioagilytix.com/techniques/instrumentation/flow-cytometers/">Flow cytometry</a>)</li><li class=""><a href="https://www.bioagilytix.com/solutions/bioanalytical-laboratory-services/biomarker-testing/">Biomarkers</a></li></ul></div></div></div><div id="block_45b11a14b91c2da7aab23e9aad18be48" class="wp-block em-media-content em-mt--none em-mb--none alignfull"><div class="em-media-content__inner em-media-content__inner--media-left has-none-background-color em-media-content__inner--content-has-padding"><div class="em-media-content__media em-media-content__media--left"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue-.jpeg" alt="" class="object-fit--cover" srcset="https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue-.jpeg 1380w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--300x169.jpeg 300w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--1024x576.jpeg 1024w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--768x432.jpeg 768w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--1120x630.jpeg 1120w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--850x478.jpeg 850w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--640x360.jpeg 640w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--100x56.jpeg 100w" width="1380" height="776"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%201380%20776%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue-.jpeg" alt="" class="lazyload object-fit--cover" data-srcset="https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue-.jpeg 1380w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--300x169.jpeg 300w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--1024x576.jpeg 1024w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--768x432.jpeg 768w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--1120x630.jpeg 1120w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--850x478.jpeg 850w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--640x360.jpeg 640w, https://www.bioagilytix.com/wp-content/uploads/2024/05/Car-T-Blue--100x56.jpeg 100w" width="1380" height="776"></div><div class="em-media-content__content em-media-content__content--right em-media-content__content--add-padding"><h3 class="h3 em-mt--xs" id="gene-services"><strong><strong>Our Expertise in Cell Therapy Bioanalysis </strong></strong></h3><p class="">BioAgilytix continues to stay at the forefront of this ever changing bioanalytical landscape. Visit our scientific insights to view content related to cell therapy from blogs and publications to webinars and videos:</p></div></div></div><div id="block_97bf194e569efce5babbd400b3f0e5d9" class="wp-block em-call-to-action em-mb--none alignfull"><div class="em-call-to-action--align-center has-primary-l-background-color has-background-opacity-- em-pt--lg em-pb--lg em-pl--md em-pr--md"><div class="em-call-to-action__inner"><h2 class="">Speak to a scientist today</h2><p class="has-em-white-color has-text-color">Learn more about how BioAgilytix can help you reach your discovery drug development goals</p><div class="wp-block-emagine-button has-text-align-left is-style-arrow-right"><a class="btn btn--size-md btn--style-primary has-quaternary-background-color" href="https://www.bioagilytix.com/speak-to-scientist/" rel=""><span>Contact <span class="btn__last-word">Bioagilytix</span></span></a></div></div></div></div></article></main><footer class="site-footer site-footer--has-logo 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