CINXE.COM

OptiGel® DR Softgel Technology - Catalent Consumer Health

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type="button" data-bs-offset="-70,0" class="btn dropdown-toggle" data-bs-toggle="dropdown" aria-expanded="false" aria-label="Show items in Nutritional Supplements"> <span class="ch-icon-chevron-down" aria-hidden="true"></span> </button> <ul class="dropdown-menu"> <li> <div class="btn-group sub dropdown"> <a class="dropdown-item" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/" title="Dose Forms" >Dose Forms</a> <button type="button" data-bs-offset="15,-73" class="btn dropdown-toggle" data-bs-toggle="dropdown" aria-expanded="false" aria-label="Show items in Dose Forms"> <span class="ch-icon-chevron-down" aria-hidden="true"></span> </button> <ul class="submenu dropdown-menu"> <li> <a class="dropdown-item" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/gummy/" title="Gummy" >Gummy</a> </li> <li> <a class="dropdown-item" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/soft-chew/" title="Soft Chew" 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href="https://consumerhealth.catalent.com/nutritional-supplements/new-to-market/" title="New-to-Market" >New-to-Market</a> <button type="button" data-bs-offset="15,-73" class="btn dropdown-toggle" data-bs-toggle="dropdown" aria-expanded="false" aria-label="Show items in New-to-Market"> <span class="ch-icon-chevron-down" aria-hidden="true"></span> </button> <ul class="submenu dropdown-menu"> <li> <a class="dropdown-item" href="https://consumerhealth.catalent.com/nutritional-supplements/new-to-market/blue-light-vegicaps-capsules/" title="Blue Light VEGICAPS® Capsules" >Blue Light VEGICAPS® Capsules</a> </li> <li> <a class="dropdown-item" href="https://consumerhealth.catalent.com/nutritional-supplements/new-to-market/joint-comfort-softgel/" title="Joint Comfort Softgel" >Joint Comfort Softgel</a> </li> <li> <a class="dropdown-item" href="https://consumerhealth.catalent.com/nutritional-supplements/new-to-market/cognitive-support-softgel/" title="Cognitive Support Softgel" >Cognitive 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href="https://consumerhealth.catalent.com/about-us/" title="About Us" >About Us</a> <button type="button" data-bs-offset="-70,0" class="btn dropdown-toggle" data-bs-toggle="dropdown" aria-expanded="false" aria-label="Show items in About Us"> <span class="ch-icon-chevron-down" aria-hidden="true"></span> </button> <ul class="dropdown-menu"> <li> <div class="btn-group"> <a class="dropdown-item" href="https://consumerhealth.catalent.com/about-us/overview/" title="Overview" >Overview</a> </div> </li> <li> <div class="btn-group"> <a class="dropdown-item" href="https://www.catalent.com/about-us/our-leadership/" title="Our Leadership" >Our Leadership</a> </div> </li> <li> <div class="btn-group"> <a class="dropdown-item" href="https://consumerhealth.catalent.com/our-locations/" title="Locations" >Locations</a> </div> </li> <li> <div class="btn-group"> <a class="dropdown-item" href="https://www.catalent.com/site-tours/" title="Site Tours" >Site Tours</a> </div> </li> <li> <div class="btn-group"> 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class="btn-icon-only" aria-label="Close menu" data-bs-dismiss="offcanvas"> <span class="ch-icon-close" aria-hidden="true"></span> </button> </div> <div class="offcanvas-body"> <ul class="mobile-menu-layout"> <li class="level1"> <div class="btn-group"> <a class="btn btn-menu " href="https://consumerhealth.catalent.com/over-the-counter/" title="OTC" >OTC</a> <button type="button" class="btn collapse-toggle collapsed" data-bs-toggle="collapse" data-bs-target="#main-menu-0" aria-expanded="false" aria-controls="main-menu-0" aria-label="Show items in OTC"> <span class="ch-icon-chevron-up" aria-hidden="true"></span> </button> </div> <ul class="collapse" id="main-menu-0"> <li class="level2"> <div class="btn-group"> <a class="btn btn-menu " href="https://consumerhealth.catalent.com/over-the-counter/softgel/" title="Softgel" >Softgel</a> <button type="button" class="btn collapse-toggle collapsed" data-bs-toggle="collapse" data-bs-target="#main-menu-0-sub-0" aria-expanded="false" aria-controls="main-menu-0-sub-0" aria-label="Show items in Softgel"> <span class="ch-icon-chevron-up" aria-hidden="true"></span> </button> </div> <ul class="collapse" id="main-menu-0-sub-0"> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/rp-scherer-softgel/" title="RP Scherer Softgel" >RP Scherer Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/optishell-technology/" title="Plant Based Softgel" >Plant Based Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/optigel-mini-technology/" title="Smaller Softgel" >Smaller Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/easyburst-chewable-softgels/" title="Chewable Softgel" >Chewable Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/optigel-micro-technology/" title="Seamless Softgel" >Seamless Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/enteric-coated-softgels/" title="Coated Softgel" >Coated Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/graphicaps-inline-printing/" title="Inline Printing" >Inline Printing</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/softgel/softgel-sizes-and-shapes/" title="Sizes And Shapes" >Sizes And Shapes</a> </div> </li> </ul> </li> <li class="level2"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/zydis-odt-technology/" title="Zydis® ODT Technology" >Zydis® ODT Technology</a> </div> </li> <li class="level2"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/flexdose-solutions/" title="FlexDose℠ Solutions" >FlexDose℠ Solutions</a> </div> </li> <li class="level2"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/over-the-counter/other-advanced-dose-forms/" title="Other Advanced Dose Forms" >Other Advanced Dose Forms</a> </div> </li> <li class="level2"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/product-library/step-2-otc/" title="Product Library" >Product Library</a> </div> </li> </ul> </li> <li class="level1"> <div class="btn-group"> <a class="btn btn-menu " href="https://consumerhealth.catalent.com/nutritional-supplements/" title="Nutritional Supplements" >Nutritional Supplements</a> <button type="button" class="btn collapse-toggle collapsed" data-bs-toggle="collapse" data-bs-target="#main-menu-1" aria-expanded="false" aria-controls="main-menu-1" aria-label="Show items in Nutritional Supplements"> <span class="ch-icon-chevron-up" aria-hidden="true"></span> </button> </div> <ul class="collapse" id="main-menu-1"> <li class="level2"> <div class="btn-group"> <a class="btn btn-menu " href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/" title="Dose Forms" >Dose Forms</a> <button type="button" class="btn collapse-toggle collapsed" data-bs-toggle="collapse" data-bs-target="#main-menu-1-sub-0" aria-expanded="false" aria-controls="main-menu-1-sub-0" aria-label="Show items in Dose Forms"> <span class="ch-icon-chevron-up" aria-hidden="true"></span> </button> </div> <ul class="collapse" id="main-menu-1-sub-0"> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/gummy/" title="Gummy" >Gummy</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/soft-chew/" title="Soft Chew" >Soft Chew Delivery Technology</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/lozenge/" title="Lozenge" >Lozenge Delivery Technology</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/vegicaps-capsules/" title="Vegicaps® Capsules" >Vegicaps® Capsules</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/easyburst-chewable-softgels/" title="EasyBurst® Chewable Softgels" >EasyBurst® Chewable Softgels</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/new-omegazero-microemulsion-technology/" title="OmegaZero® Microemulsion Technology" >OmegaZero® Microemulsion Technology</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/optigel-micro-technology/" title="OptiGel® Micro Technology" >OptiGel® Micro Technology</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/enteric-coated-softgels/" title="Coated Softgels" >Coated Softgels</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/graphicaps-inline-printing/" title="Graphicaps™ Inline Printing" >Graphicaps™ Inline Printing</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/rp-scherer-softgel/" title="RP Scherer Softgel" >RP Scherer Softgel</a> </div> </li> <li class="level3"> <div class="btn-group"> <a class="btn btn-menu no-child" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/optigel-dr-softgel-technology/" title="OptiGel® DR Softgel Technology" >OptiGel® DR Softgel Technology</a> </div> </li> 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class="et_builder_inner_content et_pb_gutters3"> <div class="et_pb_section et_pb_section_0 et_section_regular" > <div class="et_pb_row et_pb_row_0"> <div class="et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child"> <div class="et_pb_module et_pb_code et_pb_code_0"> <div class="et_pb_code_inner"><a name="top"></a></div> </div><div class="et_pb_module et_pb_dcsbcm_divi_breadcrumbs_module et_pb_dcsbcm_divi_breadcrumbs_module_0"> <div class="et_pb_module_inner"> <ol class="dcsbcm_divi_breadcrumbs" vocab="http://schema.org/" typeof="BreadcrumbList"><li class="dcsbcm_divi_breadcrumb" property="itemListElement" typeof="ListItem"><a property="item" typeof="WebPage" href="https://consumerhealth.catalent.com/"><span property="name">Home</span></a><meta property="position" content="1"></li><span class="dcsbcm_separator">&nbsp;&raquo;&nbsp;</span><li class="dcsbcm_divi_breadcrumb" property="itemListElement" typeof="ListItem"><a property="item" typeof="WebPage" href="https://consumerhealth.catalent.com/nutritional-supplements/"><span property="name">Nutritional Supplements</span></a><meta property="position" content="3"></li><span class="dcsbcm_separator">&nbsp;&raquo;&nbsp;</span><li class="dcsbcm_divi_breadcrumb" property="itemListElement" typeof="ListItem"><a property="item" typeof="WebPage" href="https://consumerhealth.catalent.com/nutritional-supplements/dose-forms/"><span property="name">Dose Forms</span></a><meta property="position" content="2"></li><span class="dcsbcm_separator">&nbsp;&raquo;&nbsp;</span><span class="dcsbcm_divi_breadcrumb dcsbcm_divi_breadcrumb-active">OptiGel® DR Softgel Technology</span></ol> </div> </div> </div> </div> </div><div class="et_pb_section et_pb_section_1 et_section_regular" > <div class="et_pb_row et_pb_row_1"> <div class="et_pb_column et_pb_column_3_4 et_pb_column_1 et_pb_css_mix_blend_mode_passthrough"> <div class="et_pb_module mugo_catalent_title mugo_catalent_title_0"> <div class="et_pb_module_inner"> <div class="ctl-title"> <div class="title-image image-large"> <img decoding="async" src="https://consumerhealth.catalent.com/wp-content/uploads/sites/4/2020/10/OptigelDR_59x59.png" alt="An optigel pill with an hour glass next to it" /> </div> <div class="title-content" style="color:#332a86 !important;"> <h1>OptiGel® DR Softgel Technology</h1> </div> </div> </div> </div> </div><div class="et_pb_column et_pb_column_1_4 et_pb_column_2 et_pb_css_mix_blend_mode_passthrough et-last-child et_pb_column_empty"> </div> </div> </div><div class="et_pb_section et_pb_section_2 et_section_specialty" > <div class="et_pb_row"> <div class="et_pb_column et_pb_column_3_4 et_pb_column_3 et_pb_specialty_column et_pb_css_mix_blend_mode_passthrough"> <div class="et_pb_row_inner et_pb_row_inner_0"> <div class="et_pb_column et_pb_column_4_4 et_pb_column_inner et_pb_column_inner_0 et-last-child"> <div class="et_pb_module et_pb_text et_pb_text_0 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><h5><a style="color: #000000;text-decoration: underline" href="#how-it-works">How it Works</a>&nbsp; &nbsp; &nbsp;<a style="color: #000000;text-decoration: underline" href="#features">Technical Features</a>&nbsp; &nbsp; &nbsp;<a style="color: #000000;text-decoration: underline" href="#benefits">Benefits</a>&nbsp; &nbsp; &nbsp;<a style="color: #000000;text-decoration: underline" href="#facilities">Facilities</a></h5></div> </div><div class="et_pb_module et_pb_divider et_pb_divider_0 et_pb_divider_position_ et_pb_space"><div class="et_pb_divider_internal"></div></div><div class="et_pb_module et_pb_text et_pb_text_1 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p>OptiGel® DR is a softgel technology that is formulated with the naturally derived polymer pectin which combines with gelatin to deliver an enteric release profile in a single-step manufacturing process without the need for coating.</p></div> </div><div class="et_pb_module et_pb_divider et_pb_divider_1 et_pb_divider_position_ et_pb_space"><div class="et_pb_divider_internal"></div></div> </div> </div><div class="et_pb_row_inner et_pb_row_inner_1"> <div class="et_pb_column et_pb_column_3_8 et_pb_column_inner et_pb_column_inner_1"> <div class="et_pb_module et_pb_image et_pb_image_0"> <span class="et_pb_image_wrap "><img fetchpriority="high" decoding="async" width="500" height="269" src="https://consumerhealth.catalent.com/wp-content/uploads/sites/4/2020/10/OptiGel-DR.jpg" alt="Graphic indicating that OptiGel DR is created by a combination of Pectin and Gelatin" title="OptiGel DR" srcset="https://consumerhealth.catalent.com/wp-content/uploads/sites/4/2020/10/OptiGel-DR.jpg 500w, https://consumerhealth.catalent.com/wp-content/uploads/sites/4/2020/10/OptiGel-DR-480x258.jpg 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) 500px, 100vw" class="wp-image-220087" /></span> </div> </div><div class="et_pb_column et_pb_column_3_8 et_pb_column_inner et_pb_column_inner_2 et-last-child"> <div class="et_pb_module et_pb_text et_pb_text_2 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p><a name="how-it-works"></a><a class="back-to-top" href="#top">Back to top</a></p> <h4>HOW IT WORKS</h4></div> </div><div class="et_pb_module et_pb_text et_pb_text_3 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><ul style="padding-bottom:0"> <li>Pectin and gelatin interact to form complex coacervates through covalent bonding</li> <li>The pectin/gelatin interaction is responsible for the enteric/delayed release properties of pectin Softgel capsules in acidic pH conditions</li> </ul></div> </div> </div> </div><div class="et_pb_row_inner et_pb_row_inner_2"> <div class="et_pb_column et_pb_column_4_4 et_pb_column_inner et_pb_column_inner_3 et-last-child"> <div class="et_pb_module et_pb_divider et_pb_divider_2 et_pb_divider_position_ et_pb_space"><div class="et_pb_divider_internal"></div></div><div class="et_pb_module et_pb_text et_pb_text_4 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p><a name="features"></a><a class="back-to-top" href="#top">Back to top</a></p> <h4>TECHNICAL FEATURES</h4></div> </div><div class="et_pb_module et_pb_text et_pb_text_5 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><ul style="padding-bottom:0px"> <li>Utilizes pectin, a biopolymer derived from fruits and vegetables</li> <li>Shell retains integrity in low pH environments such as the stomach</li> <li>Enteric release profile can be delivered without a separate coating step</li> <li>Enteric profile can be easily modified</li> <li>Capsule shell is clear and smooth</li> <li>Compatible with all ingredients suitable for gelatin softgels and potential more</li> </ul></div> </div><div class="et_pb_module et_pb_divider et_pb_divider_3 et_pb_divider_position_ et_pb_space"><div class="et_pb_divider_internal"></div></div><div class="et_pb_module et_pb_text et_pb_text_6 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p><a name="benefits"></a><a class="back-to-top" href="#top">Back to top</a></p> <h4>CONSUMER BENEFITS</h4></div> </div><div class="et_pb_module et_pb_text et_pb_text_7 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><ul style="padding-bottom:0px"> <li>Protects acid sensitive ingredients from degradation in the stomach</li> <li>May eliminate reflux and negative aftertaste from odiferous oils (e.g. fish, garlic, etc)</li> <li>Product friendly manufacturing process unlike coated softgels which expose the active to high temperature and humidity that can degrade the active</li> <li>Expands formulation capabilities vs coated softgels by removing heat degradation concerns</li> <li>Improves quality by eliminating flaking and cracking that nullify enteric properties of coated softgels</li> <li>Meets consumer expectations of softgels with smooth, easy to swallow capsules</li> <li>Shell can be crystal clear or opacified, colored, and is in-line printing compatible</li> <li>Pectin is a naturally derived GRAS and IID-listed ingredient</li> </ul></div> </div><div class="et_pb_module et_pb_divider et_pb_divider_4 et_pb_divider_position_ et_pb_space"><div class="et_pb_divider_internal"></div></div><div class="et_pb_module et_pb_text et_pb_text_8 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p><a name="facilities"></a><a class="back-to-top" href="#top">Back to top</a></p> <h4>FACILITIES</h4></div> </div><div class="et_pb_module et_pb_text et_pb_text_9 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p style="padding-bottom:1em">OptiGel DR is the latest technology from Catalent RP Scherer® Softgel – the inventors and innovators of softgel technology. We are ready to offer OptiGel DR from the facilities below to help you develop new and exciting products and bring them to market faster.</p> <ul style="padding-bottom:0px"> <li><a href="https://consumerhealth.catalent.com/our-locations/north-america/st-petersburg-usa/">St. Petersberg, FL</a></li> <li><a href="https://consumerhealth.catalent.com/our-locations/europe/aprilia-italy/">Aprilia, Italy (Coming 2022)</a></li> <li><a href="https://consumerhealth.catalent.com/our-locations/north-america/strathroy-canada/">Ontario, Canada (Coming 2022)</a></li> <li><a href="https://consumerhealth.catalent.com/our-locations/latin-america/sorocaba-brazil/">Sorocaba, Brazil (Coming 2022)</a></li> </ul></div> </div><div class="et_pb_module et_pb_divider et_pb_divider_5 et_pb_divider_position_ et_pb_space"><div class="et_pb_divider_internal"></div></div><div class="et_pb_module et_pb_text et_pb_text_10 et_pb_text_align_left et_pb_bg_layout_light"> <div class="et_pb_text_inner"><p>* These statements have not been evaluated by the Food and Drug Administration. 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