CINXE.COM

<!doctype html> <html lang="en-US"> <head>  <script src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="aca6df89-9bdc-416c-83d3-a654a702e9a4" ></script> <script type="text/javascript"> function OptanonWrapper() { } </script>  <meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1"> <meta charset="UTF-8"> <meta name="copyright" content="SomaLogic"> <meta content="initial-scale=1,width=device-width" name="viewport"> <title>COVID-19: Use case 6 - SomaLogic</title> <link href="https://somalogic.com/wp-content/themes/soma/css/fontello.css" rel="stylesheet" /> <link href="https://somalogic.com/wp-content/themes/soma/css/owl.carousel.min.css" rel="stylesheet" /> <link href="https://somalogic.com/wp-content/themes/soma/css/styles.css" rel="stylesheet" /> <link rel="shortcut icon" href="https://somalogic.com/wp-content/themes/soma/img/favicon.png" type="image/png"> <link href="https://somalogic.com/wp-content/themes/soma/css/password-form.css" rel="stylesheet" /> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' /> <style>img:is([sizes="auto" i], [sizes^="auto," i]) { contain-intrinsic-size: 3000px 1500px }</style>  <link rel="canonical" href="https://somalogic.com/covid-19/covid19-use-case-6/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="COVID-19: Use case 6 - SomaLogic" /> <meta property="og:url" content="https://somalogic.com/covid-19/covid19-use-case-6/" /> <meta property="og:site_name" content="SomaLogic" /> <meta property="article:modified_time" content="2022-07-25T15:58:53+00:00" /> <meta name="twitter:card" content="summary_large_image" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://somalogic.com/covid-19/covid19-use-case-6/","url":"https://somalogic.com/covid-19/covid19-use-case-6/","name":"COVID-19: Use case 6 - SomaLogic","isPartOf":{"@id":"https://somalogic.com/#website"},"datePublished":"2022-06-17T15:43:29+00:00","dateModified":"2022-07-25T15:58:53+00:00","breadcrumb":{"@id":"https://somalogic.com/covid-19/covid19-use-case-6/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://somalogic.com/covid-19/covid19-use-case-6/"]}]},{"@type":"BreadcrumbList","@id":"https://somalogic.com/covid-19/covid19-use-case-6/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://somalogic.com/"},{"@type":"ListItem","position":2,"name":"COVID-19","item":"https://somalogic.com/covid-19/"},{"@type":"ListItem","position":3,"name":"COVID-19: Use case 6"}]},{"@type":"WebSite","@id":"https://somalogic.com/#website","url":"https://somalogic.com/","name":"SomaLogic","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://somalogic.com/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}</script>  <link rel='dns-prefetch' href='//code.jquery.com' /> <script type="text/javascript"> /* <![CDATA[ */ window._wpemojiSettings = {"baseUrl":"https:\/\/s.w.org\/images\/core\/emoji\/15.0.3\/72x72\/","ext":".png","svgUrl":"https:\/\/s.w.org\/images\/core\/emoji\/15.0.3\/svg\/","svgExt":".svg","source":{"concatemoji":"https:\/\/somalogic.com\/wp-includes\/js\/wp-emoji-release.min.js?ver=6.7.1"}}; /*! This file is auto-generated */ !function(i,n){var o,s,e;function c(e){try{var t={supportTests:e,timestamp:(new Date).valueOf()};sessionStorage.setItem(o,JSON.stringify(t))}catch(e){}}function p(e,t,n){e.clearRect(0,0,e.canvas.width,e.canvas.height),e.fillText(t,0,0);var t=new Uint32Array(e.getImageData(0,0,e.canvas.width,e.canvas.height).data),r=(e.clearRect(0,0,e.canvas.width,e.canvas.height),e.fillText(n,0,0),new Uint32Array(e.getImageData(0,0,e.canvas.width,e.canvas.height).data));return t.every(function(e,t){return e===r[t]})}function u(e,t,n){switch(t){case"flag":return n(e,"\ud83c\udff3\ufe0f\u200d\u26a7\ufe0f","\ud83c\udff3\ufe0f\u200b\u26a7\ufe0f")?!1:!n(e,"\ud83c\uddfa\ud83c\uddf3","\ud83c\uddfa\u200b\ud83c\uddf3")&&!n(e,"\ud83c\udff4\udb40\udc67\udb40\udc62\udb40\udc65\udb40\udc6e\udb40\udc67\udb40\udc7f","\ud83c\udff4\u200b\udb40\udc67\u200b\udb40\udc62\u200b\udb40\udc65\u200b\udb40\udc6e\u200b\udb40\udc67\u200b\udb40\udc7f");case"emoji":return!n(e,"\ud83d\udc26\u200d\u2b1b","\ud83d\udc26\u200b\u2b1b")}return!1}function f(e,t,n){var r="undefined"!=typeof WorkerGlobalScope&&self instanceof WorkerGlobalScope?new OffscreenCanvas(300,150):i.createElement("canvas"),a=r.getContext("2d",{willReadFrequently:!0}),o=(a.textBaseline="top",a.font="600 32px Arial",{});return e.forEach(function(e){o[e]=t(a,e,n)}),o}function t(e){var t=i.createElement("script");t.src=e,t.defer=!0,i.head.appendChild(t)}"undefined"!=typeof Promise&&(o="wpEmojiSettingsSupports",s=["flag","emoji"],n.supports={everything:!0,everythingExceptFlag:!0},e=new Promise(function(e){i.addEventListener("DOMContentLoaded",e,{once:!0})}),new Promise(function(t){var n=function(){try{var e=JSON.parse(sessionStorage.getItem(o));if("object"==typeof e&&"number"==typeof e.timestamp&&(new Date).valueOf()<e.timestamp+604800&&"object"==typeof e.supportTests)return e.supportTests}catch(e){}return null}();if(!n){if("undefined"!=typeof Worker&&"undefined"!=typeof OffscreenCanvas&&"undefined"!=typeof URL&&URL.createObjectURL&&"undefined"!=typeof Blob)try{var e="postMessage("+f.toString()+"("+[JSON.stringify(s),u.toString(),p.toString()].join(",")+"));",r=new Blob([e],{type:"text/javascript"}),a=new Worker(URL.createObjectURL(r),{name:"wpTestEmojiSupports"});return void(a.onmessage=function(e){c(n=e.data),a.terminate(),t(n)})}catch(e){}c(n=f(s,u,p))}t(n)}).then(function(e){for(var t in e)n.supports[t]=e[t],n.supports.everything=n.supports.everything&&n.supports[t],"flag"!==t&&(n.supports.everythingExceptFlag=n.supports.everythingExceptFlag&&n.supports[t]);n.supports.everythingExceptFlag=n.supports.everythingExceptFlag&&!n.supports.flag,n.DOMReady=!1,n.readyCallback=function(){n.DOMReady=!0}}).then(function(){return e}).then(function(){var e;n.supports.everything||(n.readyCallback(),(e=n.source||{}).concatemoji?t(e.concatemoji):e.wpemoji&&e.twemoji&&(t(e.twemoji),t(e.wpemoji)))}))}((window,document),window._wpemojiSettings); /* ]]> */ </script> <style id='wp-emoji-styles-inline-css' type='text/css'> img.wp-smiley, img.emoji { display: inline !important; border: none !important; box-shadow: none !important; height: 1em !important; width: 1em !important; margin: 0 0.07em !important; vertical-align: -0.1em !important; background: none !important; padding: 0 !important; } </style> <link rel='stylesheet' id='wp-block-library-css' href='https://somalogic.com/wp-includes/css/dist/block-library/style.min.css?ver=6.7.1' type='text/css' media='all' /> <style id='classic-theme-styles-inline-css' type='text/css'> /*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} </style> <style id='global-styles-inline-css' type='text/css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:where(.is-layout-flex){gap: 0.5em;}:where(.is-layout-grid){gap: 0.5em;}body .is-layout-flex{display: flex;}.is-layout-flex{flex-wrap: wrap;align-items: center;}.is-layout-flex > :is(*, div){margin: 0;}body .is-layout-grid{display: grid;}.is-layout-grid > :is(*, div){margin: 0;}:where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;}:where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} :where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;} :where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;} :root :where(.wp-block-pullquote){font-size: 1.5em;line-height: 1.6;} </style> <style id='highcharts-custom-styles-inline-css' type='text/css'> div[class^='highstock_'], .highcharts-root, .highcharts-container { overflow: visible !important; } </style> <link rel="https://api.w.org/" href="https://somalogic.com/wp-json/" /><link rel="alternate" title="JSON" type="application/json" href="https://somalogic.com/wp-json/wp/v2/pages/593" /><link rel="EditURI" type="application/rsd+xml" title="RSD" href="https://somalogic.com/xmlrpc.php?rsd" /> <meta name="generator" content="WordPress 6.7.1" /> <link rel='shortlink' href='https://somalogic.com/?p=593' /> <link rel="alternate" title="oEmbed (JSON)" type="application/json+oembed" href="https://somalogic.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fsomalogic.com%2Fcovid-19%2Fcovid19-use-case-6%2F" /> <link rel="alternate" title="oEmbed (XML)" type="text/xml+oembed" href="https://somalogic.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fsomalogic.com%2Fcovid-19%2Fcovid19-use-case-6%2F&format=xml" /> <style type="text/css" id="wp-custom-css"> .wrap.pt-0 { padding-top: 0px; } .transparent-cards-on-black h3 { color: #59cfdb !important; } .transparent-cards-on-black p { color: white !important; } .wp-block-editor-content.wrap { padding-top: 0px; } .white-border-table table td { border-bottom: 2px solid white; border-left: 2px solid #fff; } .wrap.references-wrap { margin-top: 60px !important; } .pt-30 { padding-top: 30px; } @media (max-width: 767px){ .subgrid-item { grid-template-columns: .8fr 4fr !important; } } .subgrid-item.subgrid-6col { grid-template-columns: .8fr 5fr; align-items: center; } .subgrid-item { display: grid; grid-template-columns: subgrid; gap: 30px; grid-template-columns: .3fr 4fr; } .grid-parent { display: grid; } .secondary-level-link a:hover { cursor:pointer; color:#4067e2; font-weight:500; } div.subpages-nav-container > div { justify-content: center; } .oEmbed-reverse-order-container { display:grid; } .oEmbed-reverse-order-container .oEmbed-container-bottom-item { order:1; } .oEmbed-reverse-order-container .wistia_responsive_padding { order:0; margin-bottom:30px !important; } .video-with-border .wistia_responsive_padding { border:1px solid lightgray; } .mb-120 { margin-bottom: 120px; } .owl-carousel button { min-width: 8px; } @media only screen and (max-width: 992px) { .mobile-left-align p, .mobile-left-align h2 { text-align:left !important; } } .bynder-widget-media-link { border:0px !important; box-shadow:none !important; } div.media-item a .bynder-widget-mediaholder { background:transparent !important; } .wrap-low-bottom-padding { padding-bottom:30px !important; } #testsMenu .card img { width: 160px; height: 160px; } #platformIcons .card img { width: 110px; } .user-groups-location-cards .cards-block .card { background-size: auto 300px !important; } .nav-preview-text a { padding: 0px !important; } header { background: rgba(0,0,0, 100); } #menu-top-global li a { color:white; min-width:10px; padding: 0px 0px 0px 4px; line-height:-2em; margin-left:20px; cursor:default; } #menu-top-global li:last-child { background-image: url('https://somalogic.com/wp-content/uploads/2023/10/globeIcon.svg'); vertical-align: middle; background-repeat: no-repeat; padding:3px 10px; margin:0px; } @media (max-width: 991px){ #menu-top-global-1 > li:last-child { background-image: url('https://somalogic.com/wp-content/uploads/2023/10/globeIconBlack.svg') !important; vertical-align: middle; background-repeat: no-repeat; padding:0px 0px 0px 35px; margin:0px; } #menu-top-global-1 > li a { min-width:10px; padding-top:3px; } } .nav-primary-link > a { color: #59cfdb !important; } .nav-primary-link:before { background-color:#59cfdb !important; } .staticBlackCards>div:nth-child(2) { max-height: calc(100% + 60px); height: 523px; margin-top: -30px; margin-bottom: -30px; padding-bottom: 40px; } .consortium-tabs { margin-top:0px !important; } .user-manuals-tabs { margin-top:30px !important; } .user-manuals-tabs .tabs-nav > div, .consortium-tabs .tabs-nav > div { font-size: 14px; line-height: 21px; width: 16%; } ul.download { margin: 0 0 30px; padding: 0; list-style: none; } ul.download.small > li { padding-left: 44px; margin-bottom: 24px; } ul.download > li { position: relative; padding: 0 0 0 60px; margin: 0 0 40px; } ul.download.small > li:before { width: 30px; height: 30px; top: -4px; } ul.download > li:before { content: ""; display: block; background: url(https://somalogic.com/wp-content/uploads/2023/08/download-icon.png) no-repeat center/cover; position: absolute; left: 0; } .user-groups-speaker-cards .cards .card.white > div > h3 { font-size:18px; color:black; margin-bottom:5px; } .speaker-carousel .cards .card.transparent > div img { width:250px; } .speaker-carousel .cards .card.transparent > div h3 { display:none; } .full-width-img-cards .cards .card div p img { width:250px !important; } .full-width-ceros-row .container { width:100%; max-width: 100%; padding:0px; } .full-width-ceros .container { width:100%; max-width: 100%; padding: 0px; } .full-width-ceros, .full-width-ceros-row { padding: 0px; } .disabledComponent { display: none; } /* margin top on main page headline for side by side alignment */ @media only screen and (min-width: 992px) { .dropTitle { margin-top:90px; } } /* Begin embedded columns styling */ .embeddedCols { display:flex; align-items: flex-start; } .embeddedCols > div { width: 45%; } .embeddedCols > div > img { width:100%; } @media only screen and (max-width: 992px) { .embeddedCols { display:block; margin-bottom:30px; } .embeddedCols > div { width: 100%; } .split-bg .container .grid div::before { background-image: none !important; background-color:black; } .light-split-bg .container .grid div::before { background-image: url('https://somalogic.com/wp-content/uploads/2023/10/lightPinkBkgd.jpg') !important; } .light-split-bg .container .grid div:nth-child(2)::before { background-image:url('https://somalogic.com/wp-content/uploads/2023/10/lightTealBkgd.jpg') !important; } } @media only screen and (max-width:767px) { .desktopPhone { display:none; } .mobilePhone { display:block; } } @media only screen and (min-width:768px) { .desktopPhone { display:block; } .mobilePhone { display:none; } } </style>  <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-TJ6NK6RQ');</script>  <style> #wpadminbar{ z-index: 9999999 !important; } </style> </head> <body class="page-template-default page page-id-593 page-child parent-pageid-564 covid19-use-case-6" id="top">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-TJ6NK6RQ" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>  <header> <div class="nav-top"> <div class="container"> <div class="grid"> <div class="cell-md-4 cell-sm-12"> <div class="logo"> <a href="/"><img src="https://somalogic.com/wp-content/themes/soma/img/Somalogic-Logo.svg" alt="Somalogic logo" /></a> </div> <span class="burger"><span></span></span> </div> <div class="cell-md-8 cell-sm-12"> <ul id="menu-top-global" class="btns-menu"><li class="menu-item search-form"><form role="search" method="get" class="search-form" action="https://somalogic.com/"> <label> <div class="search-bar"> <div class="icon"></div> <div class="input"> <span class="screen-reader-text">Search for:</span> <input type="search" class="search-field" placeholder="Search …" value="" name="s" /> </div> </div> </label> <button type="submit" class="search-submit">Search</button> </form> </li><li id="menu-item-6067" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-6067"><a href="#">Global</a></li> </ul> </div> </div> </div> </div> <div class="navigation"> <div class="container"> <div class="grid"> <div class="cell-md-12 cell-sm-12"> <ul id="menu-primary" class="menu"><li id="menu-item-9526" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-9526"><a target="_blank" rel="noopener" href="https://biology.standardbio.com">Our Biology</a><div></li> <li id="menu-item-5999" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-5999"><a href="#">Platform</a><div><div class="sub"></div><div class="nav-visual"><img src="/wp-content/uploads/2022/07/Nav_Platform.jpeg" alt="Zoom in of a microscopic protein"> <p>11,000 protein measurements from a 55-µL sample.</p> <p><a href="/platform/">Explore our platform</a></p></div> <ul class="sub-menu"> <li id="menu-item-6006" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6006"><a href="#">Our Science</a><div> <ul class="sub-menu"> <li id="menu-item-6021" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6021"><a href="https://somalogic.com/somascan-platform/">SomaScan Platform</a><div></li> <li id="menu-item-8812" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-8812"><a href="https://somalogic.com/somascan-11k-assay/">SomaScan 11K Assay</a><div></li> <li id="menu-item-9544" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-9544"><a target="_blank" rel="noopener" href="https://sengenics.com/technology/">KREX® Precision Antibody Profiling</a><div></li> </ul> </li> <li id="menu-item-7862" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-7862"><a href="#">Features</a><div> <ul class="sub-menu"> <li id="menu-item-6022" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6022"><a href="https://somalogic.com/menu-size/">Menu Size</a><div></li> <li id="menu-item-9111" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-9111"><a href="https://somalogic.com/somascan-unique-scale/">Scalability</a><div></li> <li id="menu-item-6023" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6023"><a href="https://somalogic.com/dynamic-range/">Sensitivity</a><div></li> <li id="menu-item-6024" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6024"><a href="https://somalogic.com/specificity/">Specificity</a><div></li> <li id="menu-item-6025" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6025"><a href="https://somalogic.com/coefficients-of-variation/">Reproducibility</a><div></li> <li id="menu-item-7863" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-7863"><a href="https://somalogic.com/versatility/">Versatility</a><div></li> </ul> </li> </ul> </li> <li id="menu-item-6000" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6000"><a href="#">Products</a><div><div class="sub"></div><div class="nav-visual"><img src="/wp-content/uploads/2023/10/navImage_Products.jpg" alt="Scientist with a microscope"> <p class="nav-preview-text">We provide our fee-for-service proteomics platform <a href="/somascan-assay-services/">SomaScan® Assay Services</a> at our CLIA-certified, CAP-accredited laboratory.</p> <p class="nav-preview-text">SomaScan Assay Services are also accessible at all <a href="/authorized-sites-worldwide/">SomaLogic Authorized Sites worldwide.</a></p></div> <ul class="sub-menu"> <li id="menu-item-6007" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6007"><a href="#">Services</a><div> <ul class="sub-menu"> <li id="menu-item-6026" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6026"><a href="https://somalogic.com/somascan-assay-services/">SomaScan Assay Services</a><div></li> <li id="menu-item-6027" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6027"><a href="https://somalogic.com/somascan-panels/">SomaScan Panels</a><div></li> <li id="menu-item-6147" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6147"><a href="https://somalogic.com/somasignal-tests-for-research-use/">SomaSignal Tests</a><div></li> <li id="menu-item-6029" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6029"><a href="https://somalogic.com/pre-analytical-variation/">Pre-Analytical Variation</a><div></li> <li id="menu-item-9543" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-9543"><a target="_blank" rel="noopener" href="https://sengenics.com/">KREX® Precision Antibody Profiling</a><div></li> </ul> </li> <li id="menu-item-8231" class="secondary-level-link menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-8231"><a href="https://somalogic.com/authorized-sites-overview/">Authorized Sites</a><div> <ul class="sub-menu"> <li id="menu-item-8230" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-8230"><a href="https://somalogic.com/authorized-sites-overview/authorized-sites-resources/">Authorized Sites Resources</a><div></li> <li id="menu-item-6030" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6030"><a href="https://somalogic.com/authorized-sites-overview/authorized-sites/">Become a SomaLogic Authorized Site</a><div></li> <li id="menu-item-6031" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6031"><a href="https://somalogic.com/authorized-sites-worldwide/">Authorized Sites Worldwide</a><div></li> </ul> </li> <li id="menu-item-6009" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6009"><a href="#">Software and Tools</a><div> <ul class="sub-menu"> <li id="menu-item-6153" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6153"><a href="https://somalogic.com/somascan-menu/">SomaScan Menu</a><div></li> <li id="menu-item-6032" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6032"><a href="https://somalogic.com/datadelve-statistics/">DataDelve<sup>TM</sup> Statistics</a><div></li> <li id="menu-item-6033" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6033"><a href="https://somalogic.com/life-sciences-portal/">Life Sciences Customer Portal</a><div></li> <li id="menu-item-7959" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-7959"><a href="https://somalogic.com/open-source-bioinformatics-tools-for-proteomics/">Open-source Tools</a><div></li> </ul> </li> </ul> </li> <li id="menu-item-6001" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6001"><a href="#">Education</a><div><div class="sub"></div><div class="nav-visual"><img src="https://somalogic.com/wp-content/uploads/2022/10/Nav_Events.jpg" alt="Image of Stephen Williams, MD giving discussion in group setting" /> <p>See on-demand webinars highlighting proteomics.</p> <a href="https://somalogic.com/webinars/">View more</a></div> <ul class="sub-menu"> <li id="menu-item-6010" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6010"><a href="#">Webinars and Presentations</a><div> <ul class="sub-menu"> <li id="menu-item-6034" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6034"><a href="https://somalogic.com/webinars/">On-demand Webinars</a><div></li> <li id="menu-item-6050" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6050"><a href="https://somalogic.com/lab-spotlight/">Lab Spotlight – Washington University</a><div></li> </ul> </li> <li id="menu-item-6011" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6011"><a href="#">Resources</a><div> <ul class="sub-menu"> <li id="menu-item-6035" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6035"><a href="https://somalogic.com/publications/">Publications</a><div></li> <li id="menu-item-6154" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-6154"><a target="_blank" rel="noopener" href="https://menu.somalogic.com/">Menu Tool</a><div></li> <li id="menu-item-6036" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6036"><a href="https://somalogic.com/white-papers/">White Papers</a><div></li> <li id="menu-item-6037" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6037"><a href="https://somalogic.com/tech-notes/">Tech Notes</a><div></li> <li id="menu-item-6038" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6038"><a href="https://somalogic.com/posters/">Posters</a><div></li> <li id="menu-item-6039" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6039"><a href="https://somalogic.com/blog/">Blog</a><div></li> <li id="menu-item-9104" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-9104"><a href="https://somalogic.com/somascan-assay-case-study-advancing-biomarker-discovery-in-neurological-diseases-through-csf-proteomics/">Case Study: CSF Proteomics</a><div></li> <li id="menu-item-9513" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-9513"><a href="https://somalogic.com/eyeing-thousands-of-proteins-for-biomarker-discovery/">Case Study: Liquid-biopsy Proteomics</a><div></li> </ul> </li> <li id="menu-item-6012" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6012"><a href="#">Disease Spotlight</a><div> <ul class="sub-menu"> <li id="menu-item-6040" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6040"><a href="https://somalogic.com/cancer/">Cancer</a><div></li> <li id="menu-item-6041" class="menu-item menu-item-type-post_type menu-item-object-page current-page-ancestor menu-item-6041"><a href="https://somalogic.com/covid-19/">COVID-19</a><div></li> <li id="menu-item-6042" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6042"><a href="https://somalogic.com/cvd/">CVD</a><div></li> <li id="menu-item-6043" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6043"><a href="https://somalogic.com/diabetes/">Diabetes</a><div></li> <li id="menu-item-6044" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6044"><a href="https://somalogic.com/mash-nash/">MASH/NASH</a><div></li> <li id="menu-item-6045" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6045"><a href="https://somalogic.com/neurology/">Neurology</a><div></li> <li id="menu-item-6046" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6046"><a href="https://somalogic.com/rare-disease/">Rare Disease</a><div></li> </ul> </li> <li id="menu-item-6013" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6013"><a href="#">Complementary<br />Multi-omics</a><div> <ul class="sub-menu"> <li id="menu-item-6047" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6047"><a href="https://somalogic.com/why-proteins/">Why Measure Proteins?</a><div></li> <li id="menu-item-6048" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6048"><a href="https://somalogic.com/proteomics-for-genomic-analysis/">Proteomics for Genomics Analysis</a><div></li> <li id="menu-item-6049" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6049"><a href="https://somalogic.com/mass-spectrometry/">Mass Spectrometry</a><div></li> </ul> </li> <li id="menu-item-6014" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6014"><a href="#">Biobank and Cohort Research</a><div> <ul class="sub-menu"> <li id="menu-item-6051" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6051"><a href="https://somalogic.com/proteomics-consortium/">Proteomics Consortium</a><div></li> <li id="menu-item-8547" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-8547"><a href="https://somalogic.com/somascan-assay-biobanks/">SomaScan Assay Biobanks</a><div></li> </ul> </li> <li id="menu-item-6936" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6936"><a href="#">Quality and Regulatory</a><div> <ul class="sub-menu"> <li id="menu-item-6056" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6056"><a href="https://somalogic.com/quality-regulatory-a-total-quality-management-approach/">Quality Practices</a><div></li> </ul> </li> <li id="menu-item-7372" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-7372"><a href="#">Research Grants</a><div> <ul class="sub-menu"> <li id="menu-item-7373" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-7373"><a href="https://somalogic.com/uk-research-grant/">UK Research Grant</a><div></li> <li id="menu-item-8813" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-8813"><a href="https://somalogic.com/somascan-assay-australia-research-grant-award/">Australia Research Grant Award</a><div></li> </ul> </li> </ul> </li> <li id="menu-item-6002" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6002"><a href="#">About Us</a><div><div class="sub"></div><div class="nav-visual"><img src="/wp-content/uploads/2022/07/Nav_Company.jpeg" alt="Two scientists looking at a computer screen"> <p>Revolutionizing life sciences and healthcare by understanding the human proteome.</p> <p><a href="/company-overview/">See how</a></p></div> <ul class="sub-menu"> <li id="menu-item-6015" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6015"><a href="#">Company</a><div> <ul class="sub-menu"> <li id="menu-item-6052" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6052"><a href="https://somalogic.com/company-overview/">Company Overview</a><div></li> <li id="menu-item-6057" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6057"><a href="https://somalogic.com/partner-with-us/">Partner With Us</a><div></li> </ul> </li> <li id="menu-item-6016" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6016"><a href="#">Events</a><div> <ul class="sub-menu"> <li id="menu-item-6058" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6058"><a href="https://somalogic.com/conferences/">2024 Conference List</a><div></li> </ul> </li> <li id="menu-item-6017" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6017"><a href="#">Intellectual Property</a><div> <ul class="sub-menu"> <li id="menu-item-6059" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6059"><a href="https://somalogic.com/list-of-patents/">Patents</a><div></li> </ul> </li> <li id="menu-item-6018" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6018"><a href="#">Global Operations</a><div> <ul class="sub-menu"> <li id="menu-item-6060" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6060"><a href="https://somalogic.com/emea/">Europe, Middle East and Africa</a><div></li> <li id="menu-item-6061" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6061"><a href="https://somalogic.com/apac/">Asia and Pacific</a><div></li> <li id="menu-item-6062" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6062"><a href="https://somalogic.com/the-americas/">The Americas</a><div></li> </ul> </li> <li id="menu-item-6019" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6019"><a href="#">Latest News</a><div> <ul class="sub-menu"> <li id="menu-item-6064" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6064"><a href="https://somalogic.com/in-the-news/">In the News</a><div></li> </ul> </li> <li id="menu-item-6020" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-6020"><a href="#">Careers</a><div> <ul class="sub-menu"> <li id="menu-item-6065" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-6065"><a href="https://somalogic.com/work-with-us/">Work with Us</a><div></li> </ul> </li> </ul> </li> <li id="menu-item-6003" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-6003"><a target="_blank" rel="noopener" href="https://investors.standardbio.com/">Investors</a><div></li> <li id="menu-item-6004" class="nav-primary-link menu-item menu-item-type-post_type menu-item-object-page menu-item-6004"><a href="https://somalogic.com/contact-us/">Contact Us</a><div></li> <li id="menu-item-6005" class="nav-primary-link menu-item menu-item-type-post_type menu-item-object-page menu-item-6005"><a href="https://somalogic.com/portal-logins/">Login</a><div></li> </ul> <ul id="menu-top-global-1" class="btns-menu"><li class="menu-item search-form"><form role="search" method="get" class="search-form" action="https://somalogic.com/"> <label> <div class="search-bar"> <div class="icon"></div> <div class="input"> <span class="screen-reader-text">Search for:</span> <input type="search" class="search-field" placeholder="Search …" value="" name="s" /> </div> </div> </label> <button type="submit" class="search-submit">Search</button> </form> </li><li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-6067"><a href="#">Global</a></li> </ul> </div> </div> </div> </div> </div> </header> <main class="page-content"> <div class="hero" style="background-image: url(https://somalogic.com/wp-content/uploads/2022/07/Hero_Texture-10-scaled.jpeg);" title="Splash of teal and pink color"> <div class="container"> <div class="grid"> <div class="cell-md-9"> <p class="breadcrumbs"><a href="/">Home</a> / Life Science Research / Disease Spotlight / COVID-19 / <span class="blue">Facilitate Vaccine Development</span></p> <h1>COVID-19:<br /> <em class="blue">6. Facilitate vaccine development</em></h1> </div> </div> </div> </div><div class="wrap grey " id="wrap_0" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-5 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class=""><h2><em class="blue">Find</em> COVID-19 protein expression patterns to accelerate COVID-19 vaccine development</h2> </div> </div><div class="text-block cell-md-6 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class=""><ul class="blue-check"> <li>Find/monitor proteins that reflect clinical response to vaccines</li> <li>Identify immune proteins that reflect long-term clinical effect</li> <li>Accelerate vaccine development and evaluation</li> </ul> </div> </div></div> </div> </div><div class="wrap white " id="wrap_1" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class=""><h2 class="a-center">Infectious disease researchers are increasingly turning to the SomaScan® assay to monitor immune response</h2> <h3>Monitoring changes in protein levels following Swine Flu and Bird Flu infection</h3> <p>Influenza A viruses are a constant threat to public health, causing both seasonal epidemics and global pandemics. Designing safe and effective drugs is difficult because type A flu viruses can mutate quickly and because they can infect animals (such as pigs, birds, bats and horses), evolve and then reemerge in humans. Viruses use the host’s cells to replicate and spread, so identifying host factors that are affected by infection is important for developing anti-viral strategies. In this article, scientists at the University of Manitoba and the Public Health Agency of Canada examined the effects of influenza type A infection on the levels of 1310 host proteins using the SomaScan assay. They infected human lung cells with five different influenza type A viruses: three H1N1 strains (including the 2009 pandemic strain) and two avian strain (the H5N1 “Bird flu” and an H7N9 strain with low pathogenicity in birds, but high pathogenicity in humans). Compared to mock-infected cells, the levels of more than 500 proteins were changed significantly by one or more of the viruses, although no protein was changed significantly by all five. The two avian strains showed the largest effects, decreasing the levels of many proteins involved in important cell functions. These results warrant further investigation as they may help explain why the avian flu strains have such high pathogenicity in humans.</p> <p><a class="btn blue" href="https://www.ncbi.nlm.nih.gov/pubmed/31694171" target="_blank" rel="noopener">Viruses 2019</a></p> <hr /> </div> </div><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class=""><h3>Measuring proteins important for fighting lung infections</h3> <p>The body produces antimicrobial peptides and proteins (APPs) that can directly kill foreign pathogens and modulate the immune response. To better understand how APPs work in fighting lung infections, researchers at the University of Manitoba used the SomaScan assay to measure the levels of 39 APPs produced by bronchial cells before and after being stimulated by either interleukin-17 (IL-17), tumor necrosis factor (TNF), or interferon-gamma (IFN-g); three proteins that enhance airway inflammation. TNF and IL-17 caused similar responses, but IFN-g was quite distinct. These results suggest that the presence of different inflammatory proteins can affect APP production and infection control.</p> <p><a class="btn blue" href="https://www.ncbi.nlm.nih.gov/pubmed/30087279" target="_blank" rel="noopener">Vaccines 2018</a></p> <hr /> </div> </div><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class=""><h3>Assessing the effects of an antiretroviral therapy in HIV</h3> <p>HIV-infected individuals take antiretroviral therapies to help keep the virus at bay, but still suffer from systemic inflammation and immune dysfunction, which affects their quality of life and ability to survive. In this article, researchers at the Children’s Hospital of Philadelphia Research Institute and the Perelman School of Medicine at the University of Pennsylvania describe a dose and time escalation clinical trial of the anti-inflammatory drug aprepitant on 12 HIV-positive patients. The goal was to see if co-administration of aprepitant with ritonavir (an antiretroviral medication) would safely reduce residual inflammation. The SomaScan assay was used to assess the global effects of aprepitant and identified 176 plasma proteins whose levels changed after drug treatment. These included proteins involved in inflammation and immune regulation as well as blood, lipid and cholesterol metabolism, which warrant caution and further investigation.</p> <p><a class="btn blue" href="https://www.ncbi.nlm.nih.gov/pubmed/28978797" target="_blank" rel="noopener">JCI Insight 2017</a></p> </div> </div></div> </div> </div><div class="wrap black " id="wrap_2" style="background-image: url(https://somalogic.com/wp-content/uploads/2022/07/Breaker-4-scaled.jpeg)" title="Splash of teal and pink color"> <div class="container"> <div class="grid"></div> </div> </div><div class="wrap white " id="wrap_3" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><h2>Additional u<em class="blue">se cases</em></h2> </div> </div><div class="cards-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0"> <div class=" cards owl-carousel" data-items="3"><div class="card white owl-block" title="hexagon icon with number 1 inside"> <div> <p><img src="https://somalogic.com/wp-content/uploads/2022/06/covid1.png" alt="hexagon icon with number 1 inside" /></p> <h3>Predict progression</h3> <div class="content"><p>Predict which COVID-19 patients will progress and develop severe illness</p> </div> <p class="a-center"><a href="/covid-19/covid19-use-case-1" class="btn blue on-white" target="">See more</a></p> </div> </div><div class="card white owl-block" title="hexagon icon with #2 inside"> <div> <p><img src="https://somalogic.com/wp-content/uploads/2022/06/covid2.png" alt="hexagon icon with #2 inside" /></p> <h3>Identify disease subtypes</h3> <div class="content"><p>Identify COVID-19 disease complication sub-types in those at risk for severe illness</p> </div> <p class="a-center"><a href="/covid-19/covid19-use-case-2" class="btn blue on-white" target="">See more</a></p> </div> </div><div class="card white owl-block" title="hexagon icon with #3 inside"> <div> <p><img src="https://somalogic.com/wp-content/uploads/2022/06/covid3.png" alt="hexagon icon with #3 inside" /></p> <h3>Repurpose existing drugs</h3> <div class="content"><p>Repurpose existing drugs by matching them with drivers of COVID-19 progression</p> </div> <p class="a-center"><a href="/covid-19/covid19-use-case-3" class="btn blue on-white" target="">See more</a></p> </div> </div><div class="card white owl-block" title=""> <div> <p><img src="https://somalogic.com/wp-content/uploads/2022/06/covid4.png" alt="" /></p> <h3>Identify new drug candidates</h3> <div class="content"><p>Rapidly identify protein targets for new drug candidates for COVID-19</p> </div> <p class="a-center"><a href="/covid-19/covid19-use-case-4" class="btn blue on-white" target="">See more</a></p> </div> </div><div class="card white owl-block" title=""> <div> <p><img src="https://somalogic.com/wp-content/uploads/2022/06/covid5.png" alt="" /></p> <h3>Accelerate clinical trials</h3> <div class="content"><p>Accelerate clinical trials for COVID-19 drug candidates</p> </div> <p class="a-center"><a href="/covid-19/covid19-use-case-5" class="btn blue on-white" target="">See more</a></p> </div> </div></div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mt-60"><p><a class="btn blue" href="https://share.hsforms.com/1p7B2Vi0yR2avaxij5jhkug3zbc6" target="_blank" rel="noopener">Inquire about having your COVID-19 samples analyzed</a></p> </div> </div></div> </div> </div></main> <footer> <div class="footer-top"> <div class="container"> <div class="grid"> <div class="cell-md-6"> <img src="https://somalogic.com/wp-content/themes/soma/img/SomaLogic-SBI-Dual-Logo-White.svg" alt="Somalogic logo" class="footer-logo" /> <p>SomaLogic Operating Co., Inc.<br /> 2945 Wilderness Pl. Boulder, CO 80301</p> <p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-6071" src="https://somalogic.com/wp-content/uploads/2023/10/footerGlobalStatement.svg" alt="This site is intended for a global audience" width="323" height="21" /></p> </div> <div class="cell-md-6"> <div class="connect"> <div>Connect with us</div> <ul> <Li><a href="https://www.facebook.com/SomaLogicInc" aria-label="facebook_link" target="_blank"><span class="icon-facebook"></span></a></li> <Li><a href="https://twitter.com/somalogic" aria-label="twitter_link" target="_blank"><span class="icon-twitter"></span></a></li> <Li><a href="https://www.linkedin.com/company/somalogic/" aria-label="linkedin_link" target="_blank"><span class="icon-linkedin"></span></a></li> </ul> </div> </div> </div> </div> </div> <div class="footer-bottom"> <div class="container"> <div class="grid"> <div class="cell-md-4"> <ul id="menu-footer" class="menu"><li id="menu-item-735" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-735"><a href="https://somalogic.com/terms-of-use/">Terms of Use</a></li> <li id="menu-item-734" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-734"><a href="https://somalogic.com/privacy-policy/">Privacy</a></li> <li id="menu-item-733" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-733"><a href="https://somalogic.com/cookie-policy/">Cookie Policy</a></li> <li id="menu-item-732" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-732"><a href="https://somalogic.com/site-map/">Site Map</a></li> </ul> </div> <div class="cell-md-8"> For Research Use Only. Not for use in diagnostic procedures. <br class="desktop" />Limited Use Label License and other terms may apply: <a style="color:white !important" href="https://www.standardbio.com/legal/salesterms" target="_blank">www.standardbio.com/legal/salesterms</a>. Patent and License <br class="desktop" />Information: <a style="color:white !important" href="https://www.standardbio.com/legal/notices" target="_blank">www.standardbio.com/legal/notices</a>. Trademarks: <a style="color:white !important" href="https://www.standardbio.com/legal/trademarks" target="_blank">www.standardbio.com/legal/trademarks</a>. <br class="desktop" /> <br />SomaLogic, SomaScan, SOMAmer, SomaSignal, DataDelve and associated logos are trademarks of SomaLogic Operating Co., Inc., a wholly owned subsidiary of Standard BioTools Inc. Patent and Trademarks: <a style="color:white !important" href="https://somalogic.com/list-of-patents/">https://somalogic.com/list-of-patents/</a>. Any other trademarks are the sole property of their respective owners. ©2024 Standard BioTools Inc. (f.k.a. Fluidigm Corporation). All rights reserved. </div> </div> </div> </div> </footer> <script type="text/javascript" src="https://code.jquery.com/jquery-3.7.0.js" id="jquery-js"></script> <script type="text/javascript" src="https://somalogic.com/wp-content/themes/soma/js/webinar-search.js?ver=1.0.0" id="webinar-search-js"></script> <script type="text/javascript" id="webinar-search-js-after"> /* <![CDATA[ */ var webinarSearch = {"ajax_url":"https:\/\/somalogic.com\/wp-admin\/admin-ajax.php"}; /* ]]> */ </script> <script type="text/javascript" id="wdt-custom-avada-js-js-extra"> /* <![CDATA[ */ var wdt_ajax_object = {"ajaxurl":"https:\/\/somalogic.com\/wp-admin\/admin-ajax.php"}; /* ]]> */ </script> <script type="text/javascript" src="https://somalogic.com/wp-content/plugins/wpdatatables/integrations/starter/page-builders/avada/assets/js/wdt-custom-avada-js.js?ver=7.0.1" id="wdt-custom-avada-js-js"></script>  <script type="text/javascript" id="hs-script-loader" async defer src="//js.hs-scripts.com/6686502.js"></script>   <script> (function(w,q){w['QualifiedObject']=q;w[q]=w[q]||function(){ (w[q].q=w[q].q||[]).push(arguments)};})(window,'qualified') </script> <script async src="https://js.qualified.com/qualified.js?token=gfC69yQhe5A9dVMT"></script>  <script src="https://somalogic.com/wp-content/themes/soma/js/owl.carousel.min.js"></script> <script src="https://somalogic.com/wp-content/themes/soma/js/iframeResizer.min.js"></script> <script src="https://somalogic.com/wp-content/themes/soma/js/main.min.js"></script> <script type="text/javascript"> _linkedin_partner_id = "3418146"; window._linkedin_data_partner_ids = window._linkedin_data_partner_ids || []; window._linkedin_data_partner_ids.push(_linkedin_partner_id); </script><script type="text/javascript"> (function(l) { if (!l){window.lintrk = function(a,b){window.lintrk.q.push([a,b])}; window.lintrk.q=[]} var s = document.getElementsByTagName("script")[0]; var b = document.createElement("script"); b.type = "text/javascript";b.async = true; b.src = "https://snap.licdn.com/li.lms-analytics/insight.min.js"; s.parentNode.insertBefore(b, s);})(window.lintrk); </script> <noscript> <img height="1" width="1" style="display:none;" alt="" src="https://px.ads.linkedin.com/collect/?pid=3418146&fmt=gif" /> </noscript> </body> </html>