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cellspacing="0" border="0" width="649"><tr><td height="36" bgcolor="#26386B" class="ff1 cDEF p12"><span class="f65"><a href="/web/20060620061743/http://www.msnbc.msn.com/" class="lk1">MSNBC Home</a></span><span class="cFC0 b f70"> » </span><span class="f65"><a href="/web/20060620061743/http://www.msnbc.msn.com/id/3032076/" class="lk1">Health</a></span><span class="cFC0 b f70"> » </span><span class="f65"><a href="/web/20060620061743/http://www.msnbc.msn.com/id/3152832/" class="lk1">Addictions</a></span></td></tr></table><div class="clr"></div><a name="skipnav"></a><h1>Wrinkly smokers more likely to get lung disease</h1><h2>Premature aging could be a warning sign, researchers say</h2><div class="p14"><div id="finalPos"></div><div class="WCCol w300 fR clrR"><div style="padding-bottom:20px;"><script>getCSS("3088867")</script><div class="box_3088867" style="width:300;"><script></script><table width="300" cellspacing="0" cellpadding="0" class="boxH_3088867"><tr><td width="1%" 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So researchers at the Royal Devon & Exeter NHS Foundation in southwest England studied whether there was a link between the two.</p><div class="aC"><div class="textSmallGrey w320"><a href="#storyContinued">Story continues below ↓</a><hr noshade size="1"> advertisement <div style="padding:0 10 10 10;"><script>ad_dap(250,300,'&PG=NBCMSH&AP=1089');</script></div><hr noshade size="1"></div></div><a name="storyContinued"></a><p class="textBodyBlack"><span id="byLine"></span>“This data suggests that if you are a smoker and you are wrinkled you are more likely to have lung disease,” said Dr Bipen Patel who conducted the study published in the journal Thorax.</p><p class="textBodyBlack"><span id="byLine"></span>“We found that cigarette smokers who had a large amount of facial wrinkling were five times more likely to have COPD than smokers who were less wrinkled.”</p><p class="textBodyBlack"><span id="byLine"></span>COPD begins with a persistent cough and increased mucous. It eventually leads to fatigue, shortness of breath and difficulty breathing as the lungs are destroyed.</p><p class="textBodyBlack"><span id="byLine"></span>Because the disease develops gradually, Patel and his team believe facial wrinkling could be an a sign of the illness before it is diagnosed.</p><p class="textBodyBlack"><span id="byLine"></span><div class="box_brl" style="width:100%;;"><script></script><table width="100%;" cellspacing="0" cellpadding="0" class="boxH_brl"><tr><td width="*" nowrap="true" class="boxHC_brl"><div class="textSmallBold"> Click for related content</div></td></tr></table><table width="100%;" cellspacing="0" cellpadding="0" class="boxB_brl"><tr valign="top"><td class="boxBI_brl"><div class="bigRedLink"><p><a href="/web/20060620061743/http://www.msnbc.msn.com/id/12738516/">New anti-smoking drug could be available soon</a></p></div></td></tr></table></div></p><p class="textBodyBlack"><span id="byLine"></span>The researchers studied 149 former and current middle-aged smokers and compared how much they smoked during their lifetime and their sun exposure, which also damages the skin.</p><p class="textBodyBlack"><span id="byLine"></span>Two dermatologists scored the severity of wrinkling from photographs of the smokers. Breathing tests and scans were also done to detect any signs of COPD.</p><p class="textBodyBlack"><span id="byLine"></span><b><strong>Unknown link<br></strong></b>The smokers who were the most wrinkled were far more likely to have changes in their lungs suggesting COPD, according to the scientists.</p><p class="textBodyBlack"><span id="byLine"></span>They suspect there could be an unknown common mechanism linking COPD and wrinkling.</p><p class="textBodyBlack"><span id="byLine"></span>“This is the first time that it has been shown that the two are more likely to occur together,” he added.</p><p class="textBodyBlack"><span id="byLine"></span>Deaths from COPD are increasing in most countries. The World Health Organization (WHO) estimates it will become the third-biggest cause of death worldwide by 2020.</p><p class="textBodyBlack"><span id="byLine"></span>The illness afflicts people over 40 who have been smoking for many years. It contributes to other disorders such as pneumonia, heart disease and stroke. There is no cure for COPD but treatment can relieve the symptoms and therapies to slow its progression are being tested.</p><div class="textBodyBlack"><i><em>Copyright 2006 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content is expressly prohibited without the prior written consent of Reuters.</em></i></div><div class="userRating t1 b f11 c000" style="margin-top:20px;"><nobr> Rate this story </nobr><span style="white-space:wrap;"></span><nobr> Low <span id="URplace"></span> High </nobr></div><span class="t1 f11 c000" style="display:none" id="userRatingTotal"></span><span> </span><span class="bulletRedSmall"> • </span><a href="/web/20060620061743/http://www.msnbc.msn.com/id/7468311/" class="t1 b f11 c000">View Top Rated stories</a><br><script>moveURCode();</script><br><div class="textMedBlack doThis" style="text-align:center"><span class="dSp"><a href="javascript:printThis('13316488')"><img border="0" class="dIc" src="/web/20060620061743im_/http://www.msnbc.msn.com/images/msnbc/print02.gif"></a> <a href="javascript:printThis('13316488')">Print this</a></span><span class="dSp"><a href="javascript:emThis('13316488')"><img border="0" class="dIc" 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