Biomarkers · 360biolabs

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Biomarker assays can also validate targets and identify potential toxicity. We use LC-MS/MS, single or multiplex ligand-binding assays and have a range of instruments to allow analysis of absorbance, fluorescence, and chemiluminescence output (MSD, Simoa, Tecan, and Luminex).</p> </div> </div> </div> <img src="https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/hero-shape.svg" alt="Decorative image" class="bottom-decoration" data-neruda-anim="hero-shape"> <div class="icon-bg" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-biodistribution-default.svg')" data-neruda-anim="fade-left"></div> </section> <div class="services-page-anchor"> <div class="button-page-scroll-container"> <a href="#page-content" class="button-page-scroll"> <span aria-hidden="false">Scroll to page content</span> </a> </div> <a id="page-content"></a> </div> <section class="content-block block-pill-image-text"> <div class="container is-wide"> <div class="columns"> <div class="column-content"> <div class="inner-padding"> <h2>Expertise With  Biomarkers:</h2> <div class="features-container"> <div class="feature" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-measuring-cylinder-circle.svg');"> <h3>Extensive Experience </h3> <p>We have experience with 500+ biomarkers in singleplex and multiplex formats for a wide range of disease states.</p> </div> <div class="feature" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-ideas-circle.svg');"> <h3>Custom Assay Solutions</h3> <p>360biolabs provides a diverse range of simple to highly complex biomarker assays for use across various technologies and multiple matrices, including serum, plasma, ex-vivo stimulated whole blood, urine, CSF, and tissue homogenates.</p> </div> <div class="feature" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-science-driven-circle.svg');"> <h3>Modalities </h3> <p>Biomarker analysis to support large-molecule, small-molecule, cell-based, and advanced therapies throughout the drug development and clinical testing process.</p> </div> <div class="feature" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-quality-circle.svg');"> <h3>Quality Compliance </h3> <p>Our expert team is knowledgeable in regulatory expectations for biomarker analytical validations based on the context of use.</p> </div> </div> </div> </div> <div class="column-image"> <div class="image-container" > <figure> <img width="1920" height="1280" src="https://www.360biolabs.com/wp-content/uploads/Biomarkers_6653.webp" class="attachment-full size-full" alt="Scientists in lab pipetting samples for biomarker testing on The MesoScale Discovery platform (MSD)" decoding="async" fetchpriority="high" srcset="https://www.360biolabs.com/wp-content/uploads/Biomarkers_6653.webp 1920w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_6653-600x400.webp 600w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_6653-1400x933.webp 1400w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_6653-768x512.webp 768w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_6653-1536x1024.webp 1536w" sizes="(max-width: 1920px) 100vw, 1920px" /> </figure> <div class="shape has-cyan-fair-bg" ></div> </div> <div class="section-action"> <a href="https://www.360biolabs.com/contact/" target="_self">Make the right bioanalytical method selection with our help</a> </div> </div> </div> </div> </section> <section class="content-block block-services-x3"> <div class="container"> <h2 class="is-centered">360biolabs Bioanalytical Services</h2> <div class="services-container"> <div class="service" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-soluble-biomarkers-colour.svg')"> <div class="service-top"> <h3>Soluble Biomarkers</h3> <div class="description"> <p>Assess biological indicators of normal biological processes, disease progression, or responses to treatment interventions via our diverse platforms. </p> </div> </div> <a href="https://www.360biolabs.com/contact/" target="_self" class="button"> <span>Discuss Clinical Study</span> </a> </div> <div class="service" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-molecular-assays-colour.svg')"> <div class="service-top"> <h3>Molecular Biomarkers</h3> <div class="description"> <p>Qualitatively or quantitatively measure the presence, amount, or functional activity of a target entity using qPCR or digital PCR. </p> </div> </div> <a href="https://www.360biolabs.com/molecular-assays/" target="_self" class="button"> <span>Explore Assay</span> </a> </div> <div class="service" style="background-image:url('https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/icons-library/icon-biodistribution-colour.svg')"> <div class="service-top"> <h3>Cellular Biomarkers</h3> <div class="description"> <p>Our advanced platforms and extensive expertise can assess any cellular response that can be done with flow cytometry.</p> </div> </div> <a href="https://www.360biolabs.com/flow-cytometry/" target="_self" class="button"> <span>Explore Assay</span> </a> </div> </div> </div> </section> <section class="content-block block-checklist has-steel-fair-bg"> <div class="container"> <div class="columns flex-justify-md"> <div class="column column-heading"> <h2>360biolabs has a <br /> wide-variety of<br /> <strong>advanced platforms</strong>.</h2> </div> <div class="column column-list"> <ul class="list-unformatted"> <li>ELISA</li> <li>MSD-ECL</li> <li>Quanterix</li> <li>SIMOA®</li> <li>Luminex™</li> <li>Flow Cytometry</li> <li>LC-MS/MS</li> <li>qPCR</li> <li>dPCR</li> <li>ELISpot</li> </ul> </div> </div> </div> <div class="hero-image content-block block-hero-image has-half-bg"> <div class="container is-default"> <figure> <img width="1920" height="1280" src="https://www.360biolabs.com/wp-content/uploads/Biomarkers_Simoa_9643.webp" class="attachment-full size-full" alt="Scientists in lab using Quanterix Simoa for sensitive detection of analytes in biomarker samples" decoding="async" srcset="https://www.360biolabs.com/wp-content/uploads/Biomarkers_Simoa_9643.webp 1920w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_Simoa_9643-600x400.webp 600w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_Simoa_9643-1400x933.webp 1400w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_Simoa_9643-768x512.webp 768w, https://www.360biolabs.com/wp-content/uploads/Biomarkers_Simoa_9643-1536x1024.webp 1536w" sizes="(max-width: 1920px) 100vw, 1920px" /> </figure> </div> </div> </section> <section class="content-block block-related-content"> <div class="container"> <h2 class="is-centered">Related Content</h2> <div class="columns"> <div class="column"> <figure> <img width="600" height="400" src="https://www.360biolabs.com/wp-content/uploads/PK_ADA_9575-600x400.webp" class="attachment-medium size-medium" alt="Scientists in biosafety cabinet accurately pipetting samples for an immunogenicity assay" decoding="async" srcset="https://www.360biolabs.com/wp-content/uploads/PK_ADA_9575-600x400.webp 600w, https://www.360biolabs.com/wp-content/uploads/PK_ADA_9575-1400x933.webp 1400w, https://www.360biolabs.com/wp-content/uploads/PK_ADA_9575-768x512.webp 768w, https://www.360biolabs.com/wp-content/uploads/PK_ADA_9575-1536x1024.webp 1536w, https://www.360biolabs.com/wp-content/uploads/PK_ADA_9575.webp 1920w" sizes="(max-width: 600px) 100vw, 600px" /> </figure> <div class="text-container"> <h3>Pharmacodynamics</h3> <div class="column-blurb"> <p>PD biomarkers are used in preclinical and clinical investigations to establish optimal dosing schedules & assess therapeutic effectiveness. </p> </div> <p class="column-action"> <a href="https://www.360biolabs.com/pharmacodynamics/"> Learn more</a> </p> </div> </div> <div class="column"> <figure> <img width="600" height="400" src="https://www.360biolabs.com/wp-content/uploads/Photo-Feature_Biomarkers-detail-600x400.webp" class="attachment-medium size-medium" alt="Pipetting for accurate, precise and robust sample analysis" decoding="async" loading="lazy" srcset="https://www.360biolabs.com/wp-content/uploads/Photo-Feature_Biomarkers-detail-600x400.webp 600w, https://www.360biolabs.com/wp-content/uploads/Photo-Feature_Biomarkers-detail-1400x933.webp 1400w, https://www.360biolabs.com/wp-content/uploads/Photo-Feature_Biomarkers-detail-768x512.webp 768w, https://www.360biolabs.com/wp-content/uploads/Photo-Feature_Biomarkers-detail-1536x1024.webp 1536w, https://www.360biolabs.com/wp-content/uploads/Photo-Feature_Biomarkers-detail.webp 1920w" sizes="(max-width: 600px) 100vw, 600px" /> </figure> <div class="text-container"> <h3>Blog: Biomarkers</h3> <div class="column-blurb"> <p>Read about our experience with biomarkers in our latest blog: Biomarkers as Tools to Assess and Predict Clinical Efficacy.</p> </div> <p class="column-action"> <a href="https://www.360biolabs.com/biomarkers-as-tools-to-assess-and-predict-clinical-efficacy/"> Learn more</a> </p> </div> </div> <div class="column"> <figure> <img width="600" height="400" src="https://www.360biolabs.com/wp-content/uploads/exteriors-20-of-20.dng-1-600x400.webp" class="attachment-medium size-medium" alt="BioAgilytix Durham bioanalytical facility" decoding="async" loading="lazy" srcset="https://www.360biolabs.com/wp-content/uploads/exteriors-20-of-20.dng-1-600x400.webp 600w, https://www.360biolabs.com/wp-content/uploads/exteriors-20-of-20.dng-1-768x512.webp 768w, https://www.360biolabs.com/wp-content/uploads/exteriors-20-of-20.dng-1.webp 1024w" sizes="(max-width: 600px) 100vw, 600px" /> </figure> <div class="text-container"> <h3>BioAgilytix Global Team</h3> <div class="column-blurb"> <p>Our global team provides comprehensive end-to-end bioanalytical support for all your clinical trial phases. </p> </div> <p class="column-action"> <a href="https://www.360biolabs.com/bioagilytix/"> Learn more</a> </p> </div> </div> </div> </div> </section> </main> <section class="block-footer-cta"> <div class="container is-default"> <div class="columns"> <div class="column-text"> <p>Enabling future medicine together. Contact our team today to start your next early-phase clinical trial.</p> </div> <div class="column-cta"> <p> <a href="https://www.360biolabs.com/contact/" target="_self" class="button"> <span>Connect With Us</span> </a> </p> </div> </div> </div> </section> <footer id="main-footer"> <div class="container"> <div class="columns-top"> <div class="column-contact"> <a href="https://www.360biolabs.com" class="biolabs-footer-logo hover-default"> <img src="https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/360biolabs-logo-reversed.webp" loading="lazy" alt="360biolabs logo"> </a> <h5>General Inquires</h5> <p><a href="https://www.360biolabs.com/contact/">Send us a message</a></p> <a href="https://www.bioagilytix.com/" target="_blank" rel="noopener" class="bioagilytix-footer-logo hover-default"> <img src="https://www.360biolabs.com/wp-content/themes/cc-360biolabs/assets/images/bioagilytix-logo-reversed.svg" loading="lazy" alt="BioAgilytix logo"> </a> </div> <div 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