Section of Sensory Science, and Metabolism | National Institute on Alcohol Abuse and Alcoholism (NIAAA)

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and Metabolism logo" loading="lazy" /> </div> </div> </article> </div> </div> <div class="lab-info row"> <div class="col-12 col-tablet-8 lab-info-chief"> <div> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/SSSM_PauleJoseph.png?itok=B2QMyUdF" width="220" height="220" alt="Dr. Paule Joseph" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Lasker Clinical Research Scholar</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/paule-v-joseph-phd" rel="bookmark">Paule Valery Joseph, CRNP, Ph.D.</a></h3> <p class="profile-item-email"> <a href="mailto:paule.joseph@nih.gov">paule.joseph@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> </div> <div class="col-12 col-tablet-4 lab-info-contact"> <div class="contact-labs "> <h3 class="h3">Contact Information</h3> <ul class="contact-labs-list"> <li class="contact-labs-list-item">Office: <a href="tel:301-827-5234">301-827-5234</a></li> <li class="contact-labs-list-item">Lab: <a href="tel:301-339-4869">301-339-4869</a></li> <li class="contact-labs-list-item">Fax: <a href="tel:301-480-1413">301- 480-1413</a></li> <li class="contact-labs-list-item"><div class="mail-address" aria-expanded="false">Mailing Address <i class="fas fa-sort-down fa-pull-right" aria-hidden="true" title="See more info" aria-label="Sort down"></i></div> <div class="mail-address-content contact-labs-address-panel" aria-hidden="true"> <p> Section of Sensory Science, and Metabolism (SenSMet) <br/> 10 Center Drive<br/> Building 10, Room 2A07 <br/> Bethesda, MD 20892 </p> </div> </li> </ul> </div>  </div> </div> <div class="content-river"> <div class="drawer-wrapper"> <h3>Overview of the Lab</h3> <div class="drawer-peek"> <div class="drawer-expand"> <div class="content-field "> <p>Our senses are essential for us to interact with the world. Our five senses–sight, hearing, touch, taste, and smell work closely to enable the mind to understand its surroundings better. In humans, chemical senses mediate safety, nutrition, the sensation of pleasure, and general well-being. Taste, olfaction, and chemesthesis (refers to chemical irritation from the burning of chili peppers, the cooling of menthol, and the tingling of soda) are involved in the perception of flavor for food and beverages. Chemosensory perceptions, which can influence food/beverage choices and consumption, may be altered and differ in individuals with obesity and alcohol use disorder. Given that both obesity and excessive alcohol consumption are major public health issues, our lab focuses on these two disorders to further characterize how the chemical senses may be contributing to the mechanism of alcohol consumption and overeating. Currently, little is known about the underlying neurobiological and molecular mechanisms causing variations in the chemosensory systems in individuals with obesity and alcohol use disorder, limiting the interventions currently available to address these critical issues.</p> <h2>Mission Statement</h2> <p>The Section of Sensory Science and Metabolism (SenSMet) aims to understand neuronal and molecular mechanisms underlying chemosensation (taste, smell & chemesthesis), in addition to understanding motivational and reward pathways of ingestive behaviors and how they might differ in individuals with obesity and alcohol and substance use disorders. We are particularly interested in studying how the brain incorporates chemosensory information from the external environment and its internal states to guide eating/ingestive behavior. To achieve this goal, our laboratory conducts clinical-translational inpatient and outpatient studies. We use a combination of biobehavioral and innovative validated psychophysical methods for human studies. We also use imaging brain techniques, such as fMRI for olfaction and gustation. To provide mechanistic insight into our clinical research, we are also conducting preclinical studies using rodent models to understand cellular and molecular mechanisms that influence how the brain perceives the chemical senses (taste, smell, chemesthesis) and feeding behavior in a state of disease (e.g., obesity and substance use disorders). The SenSMet lab is currently investigating the interplay among biological and behavioral components of chemosensation in the context of diseases, with a particular emphasis on metabolic disorders like obesity and brain diseases, particularly alcohol and substance use disorders, given that both obesity and alcohol and substance use disorders share common brain mechanisms associated with the chemical senses. Besides, due to reports of taste and smell loss from individuals affected by COVID-19, our lab began investigating chemosensation and COVID-19. We want to understand the effects of the SARS-CoV-2 virus on the chemical senses.</p> </div>  </div> <div class="drawer-peek-foot"> <button class="button " aria-expanded="false" aria-label="More infomation"> <span> Read More <i class="fas fa-long-arrow-alt-down" aria-hidden="true" title="More infomation" role="img"></i> </span> <span class="hidden">Close <i class="fas fa-long-arrow-alt-up" title="long arrow up" aria-labelledby="long arrow up"></i> </span> </button> </div> </div>  </div>  <div class="drawer-wrapper"> <h3>Research Projects</h3> <div class="drawer-peek"> <div class="drawer-expand"> <div class="content-field "> <p>We are addressing the following questions:</p> <ul> <li>How is chemosensation altered in AUD and obesity and what molecular pathways are perturbated associated with chemosensation?</li> <li>How processing of taste (fat, salt, umami, bitter, and sour) and smell in the brain influences hedonic responses, eating and alcohol seeking behaviors?</li> <li>What are mechanisms by which SARS-CoV-2 affects the chemical senses?</li> </ul> </div>  </div> <div class="drawer-peek-foot"> <button class="button " aria-expanded="false" aria-label="More infomation"> <span> Read More <i class="fas fa-long-arrow-alt-down" aria-hidden="true" title="More infomation" role="img"></i> </span> <span class="hidden">Close <i class="fas fa-long-arrow-alt-up" title="long arrow up" aria-labelledby="long arrow up"></i> </span> </button> </div> </div>  </div>  <div class="drawer-wrapper"> <h3>Clinical Protocol</h3> <div class="drawer-peek"> <div class="drawer-expand"> <div class="content-field "> <p><strong>SenSmet Protocols</strong></p> <ol> <li><a href="https://clinicaltrials.gov/ct2/show/NCT04714892?recrs=ab&cond=Taste+smell+obesity&draw=2&rank=1">Mechanisms Underlying Individual Variations of Taste and Smell in Obesity</a></li> <li><a href="https://www.clinicaltrials.gov/study/NCT05677321?locStr=Bethesda,%20MD,%20USA&country=United%20States&state=Maryland&city=Bethesda&distance=50&cond=Alcohol%20Use%20Disorder&rank=1">Individual Variations of Taste and Smell Perception in</a><a href="https://clinicaltrials.gov/ct2/show/NCT04714892?recrs=ab&cond=Taste+smell+obesity&draw=2&rank=1"> </a><a href="https://www.clinicaltrials.gov/study/NCT05677321?locStr=Bethesda,%20MD,%20USA&country=United%20States&state=Maryland&city=Bethesda&distance=50&cond=Alcohol%20Use%20Disorder&rank=1">Alcohol Use Disorder (AUD)</a></li> </ol> <p><strong>Collaborative Protocols:</strong></p> <ol> <li><a href="https://clinicalstudies.info.nih.gov/ProtocolDetails.aspx?A_2014-AA-0181.html">Unit and Clinic Evaluation, Screening, Assessment and Management (14-AA-0181) </a></li> <li><a href="https://clinicalstudies.info.nih.gov/ProtocolDetails.aspx?A_2017-AA-0093.html">Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder via Microbiota Investigations: A Pilot Study (17-AA-0093) </a></li> <li><a href="https://clinicaltrials.gov/ct2/show/NCT04391816">COVID-19 Pandemic Impact on Alcohol and Related Outcomes</a></li> <li><a href="https://clinicaltrials.gov/ct2/show/NCT04348240">Transmissibility and viral load of SARS-COV2 through oral secretions</a></li> <li><a href="https://clinicalstudies.info.nih.gov/ProtocolDetails.aspx?A_18-DK-0132.html%20@External@healthy">Brain Dopamine Function in Human Obesity (18-DK-0132)</a></li> <li><a href="https://clinicalstudies.info.nih.gov/ProtocolDetails.aspx?A_2014-HG-0048.html">GENE-FORECASTSM: Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (14-HG-0048)</a></li> </ol> </div>  </div> <div class="drawer-peek-foot"> <button class="button " aria-expanded="false" aria-label="More infomation"> <span> Read More <i class="fas fa-long-arrow-alt-down" aria-hidden="true" title="More infomation" role="img"></i> </span> <span class="hidden">Close <i class="fas fa-long-arrow-alt-up" title="long arrow up" aria-labelledby="long arrow up"></i> </span> </button> </div> </div>  </div>  <div class="drawer-wrapper"> <h3>Lab Members</h3> <div class="drawer-peek drawer-peek-member"> <div class="drawer-expand"> <div class="content-field "> <div class="content-field-member"> <div class="row"> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Carolyn%20Allen.jpg?itok=31f6IwOV" width="200" height="200" alt="Carolyn Allen" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Family Nurse Practitioner</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/carolyn-allen-dnp" rel="bookmark">Carolyn Allen, M.S., CRNP</a></h3> <p class="profile-item-email"> <a href="mailto:carolyn.allen@nih.gov">carolyn.allen@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Headshoot_NIAAA%20-%20Colina-Prisco.png?itok=fGd65PGN" width="176" height="220" alt="Dr. Claudia Colina-Prisco" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Scientist</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/claudia-colina-prisco-phd" rel="bookmark">Claudia Colina-Prisco, Ph.D.</a></h3> <p class="profile-item-email"> <a href="mailto:claudia.colina-prisco@mail.nih.gov">claudia.colina-prisco@mail.nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Rosario%20Jaime-Lara.jpg?itok=FtXd7Guf" width="220" height="220" alt="image of Rosario Jaime-Lara" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Special Volunteer</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/rosario-jaime-lara" rel="bookmark">Rosario Jaime-Lara, CRNP, Ph.D.</a></h3> <p class="profile-item-email"> <a href="mailto:rosario.jaime-lara@nih.gov">rosario.jaime-lara@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Khushbu%20Agarwal.jpg?itok=gEsOPI4O" width="220" height="220" alt="image of Khushbu Agarwal" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Post-Doctoral Visiting Fellow</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/khushbu-agarwal" rel="bookmark">Khushbu Agarwal, Ph.D.</a></h3> <p class="profile-item-email"> <a href="mailto:khushbu.agarwal@nih.gov">khushbu.agarwal@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Ana%20Diallo.png?itok=TTeJB8CI" width="179" height="179" alt="Image of Ana Diallo" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Volunteer</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/ana-diallo" rel="bookmark">Ana Diallo, M.S., Ph.D., M.P.H</a></h3> <p class="profile-item-email"> <a href="mailto:ana.diallo@nih.gov">ana.diallo@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Yupeng%20Wang.jpg?itok=XrC-fybz" width="220" height="220" alt="image of Yupeng Wang" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Bioinformatician (Contractor)</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/yupeng-wang" rel="bookmark">Yupeng Wang, Ph.D.</a></h3> <p class="profile-item-email"> <a href="mailto:Yupeng.wang@nih.gov">Yupeng.wang@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Nafisa%20Nawal.png?itok=u0cNMP1s" width="220" height="212" alt="Nafisa Nawal Post bac IRTA" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title"> Postbaccalaureate IRTA</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/nafisa-nawal" rel="bookmark">Nafisa Nawal</a></h3> <p class="profile-item-email"> <a href="mailto:nafisa.nawal@nih.gov">nafisa.nawal@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/Photo-Meaghan%20S..png?itok=VpZxOejT" width="179" height="220" alt="Meaghan S post bac IRTA" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title"> Postbaccalaureate IRTA</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/meaghan-steck" rel="bookmark">Meaghan Steck</a></h3> <p class="profile-item-email"> <a href="mailto:meaghan.steck@nih.gov">meaghan.steck@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> <div class="col-12 col-tablet-6"> <article> <div class="profile-item-small "> <div class="profile-item-image"> <div> <img loading="lazy" src="/sites/default/files/styles/medium/public/headshot%20Marinza%20M_png.png?itok=raYfmjwF" width="210" height="220" alt="Marinza M post bac IRTA" /> </div> </div> <div class="profile-item-content"> <p class="profile-item-title">Post-baccalaureate fellow</p> <h3 class="profile-item-name"><a href="/about-niaaa/our-staff/marinza-marzouk" rel="bookmark">Marinza Marzouk</a></h3> <p class="profile-item-email"> <a href="mailto:marinza.marzouk@nih.gov">marinza.marzouk@nih.gov</a> <i class="fas fa-envelope" aria-hidden="true" title="email link" aria-label="email icon"></i> </p> </div> </div>  </article> </div> </div> </div> </div>  </div> <div class="drawer-peek-foot"> <button class="button " aria-expanded="false" aria-label="More infomation"> <span> Read More <i class="fas fa-long-arrow-alt-down" aria-hidden="true" title="More infomation" role="img"></i> </span> <span class="hidden">Close <i class="fas fa-long-arrow-alt-up" title="long arrow up" aria-labelledby="long arrow up"></i> </span> </button> </div> </div>  </div>  <div class="drawer-wrapper"> <h3>Selected Publications</h3> <div class="drawer-peek drawer-peek-large"> <div class="drawer-expand"> <div class="content-field large-content-field"> <div><p>Joseph PV, Reed DR, Mennella JA. Individual Differences Among Children in Sucrose Detection Thresholds: Relationship With Age, Gender, and Bitter Taste Genotype. Nurs Res. 2016 Jan-Feb;65(1):3-12. doi: 10.1097/NNR.0000000000000138. PMID: 26633761; PMCID: PMC4679349.<br>  <br> Cooper KW, Brann DH, Farruggia MC, Bhutani S, Pellegrino R, Tsukahara T, Weinreb C, Joseph PV, Larson ED, Parma V, Albers MW, Barlow LA, Datta SR, Di Pizio A. COVID-19 and the Chemical Senses: Supporting Players Take Center Stage. Neuron. 2020 Jul 22;107(2):219-233. doi: 10.1016/j.neuron.2020.06.032. Epub 2020 Jul 1. PMID: 32640192; PMCID: PMC7328585.</p> <p>Gerkin RC, Ohla K, Veldhuizen MG, Joseph PV, et al. Recent smell loss is the best predictor of COVID-19: a preregistered, cross-sectional study. Chemical Senses, bjaa081, doi: 10.1093/chemse/bjaa081 PMID: 32743605; PMCID: PMC7386529. </p> <p>Joseph PV, Nolden A, Kober KM, Paul SM, Cooper BA, Conley YP, Hammer MJ, Wright F, Levine JD, Miaskowski C. Fatigue, Stress, and Functional Status are Associated With Taste Changes in Oncology Patients Receiving Chemotherapy. J Pain Symptom Manage. 2020 Nov 28:S0885-3924(20)30899-X. doi: 10.1016/j.jpainsymman.2020.11.029. Epub ahead of print. PMID: 33259906.<br>  <br> Joseph PV, Wang Y, Fourie NH, Henderson WA. A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles. PLoS One. 2018 May 24;13(5):e0197843. doi: 10.1371/journal.pone.0197843. PMID: 29795655; PMCID: PMC5993110.<br>  <br> Joseph PV, Davidson HR, Boulineaux CM, Fourie NH, Franks AT, Abey SK, Henderson WA. Eating Behavior, Stress, and Adiposity: Discordance Between Perception and Physiology. Biol Res Nurs. 2018 Oct;20(5):531-540. doi: 10.1177/1099800418779460. Epub 2018 May 31. PMID: 29852756; PMCID: PMC6346320.<br>  <br> Joseph PV, Jaime-Lara RB, Wang Y, Xiang L, Henderson WA. Comprehensive and Systematic Analysis of Gene Expression Patterns Associated with Body Mass Index. Sci Rep. 2019 May 15;9(1):7447. doi: 10.1038/s41598-019-43881-5. PMID: 31092860; PMCID: PMC6520409.<br>  <br> Hall KD, Ayuketah A, Brychta R, Cai H, Cassimatis T, Chen KY, Chung ST, Costa E, Courville A, Darcey V, Fletcher LA, Forde CG, Gharib AM, Guo J, Howard R, Joseph PV, McGehee S, Ouwerkerk R, Raisinger K, Rozga I, Stagliano M, Walter M, Walter PJ, Yang S, Zhou M. Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake. Cell Metab. 2019 Jul 2;30(1):67-77.e3. doi: 10.1016/j.cmet.2019.05.008. Epub 2019 May 16. Erratum in: Cell Metab. 2019 Jul 2;30(1):226. Erratum in: Cell Metab. 2020 Oct 6;32(4):690. PMID: 31105044.<br>  <br> Kure Liu C, Joseph PV, Feldman DE, Kroll DS, Burns JA, Manza P, Volkow ND, Wang GJ. Brain Imaging of Taste Perception in Obesity: a Review. Curr Nutr Rep. 2019 Jun;8(2):108-119. doi: 10.1007/s13668-019-0269-y. PMID: 30945140; PMCID: PMC6486899.<br>  </p> </div> </div>  </div> <div class="drawer-peek-foot"> <button class="button " aria-expanded="false" aria-label="More infomation"> <span> Read More <i class="fas fa-long-arrow-alt-down" aria-hidden="true" title="More infomation" role="img"></i> </span> <span class="hidden">Close <i class="fas fa-long-arrow-alt-up" title="long arrow up" aria-labelledby="long arrow up"></i> </span> </button> </div> </div>  </div>  <div class="drawer-wrapper"> <h3>Other Lab Resources</h3> <div class="drawer-peek"> <div class="drawer-expand"> <div class="content-field "> <p><strong>Alumni </strong></p> <p>Postdoctoral Fellows</p> <ul> <li>Carlotta Vizioli, PhD, Postdoctoral Visiting Fellow 2019-2021, Research Fellow, NIH National Institute of Neurological Disorders and Stroke (NINDS)</li> <li>Markos Tesfaye, MD, PhD, Postdoctoral Visiting Fellow 2019-2021, Associate Professor of Psychiatry at<br> Jimma University, Ethiopia</li> </ul> <p>Postbaccalaurate Fellows </p> <ul> <li>Alexis Franks, BS., Post -Bac IRTA Fellow 2017-2020, Doctor of Physical Therapy student at Duke University </li> <li>Abhrarup (Abe) Roy, BS., Post -Bac IRTA Fellow 2017-2019, Medical Student, Cooper Hospital</li> <li>Brianna Brooks, BA, Postbaccalaureate IRTA, 2019-2021, PhD Student in Nutrition, Columbia University</li> <li>Rodrigo Ortiz, BS, Postbaccalaureate IRTA, NIH Academy 2019-2021, Medical Student at Ponce Health<br> Sciences University</li> <li>Leann To, BS, Postbaccalaureate IRTA, NIH Academy 2021-2022, University of Pittsburgh, Pittsburgh,<br> PA, Master of Science in Genetic Counseling</li> <li>Christian McDuffie, BS, Postbaccalaureate IRTA, NIH Academy 2020-2022, Masters in Public Health, George<br> Washington University</li> </ul> <p><strong>Summer Fellows </strong></p> <ul> <li>Emma Butturini, AMGEN Scholar, Summer Internship Program 2017 </li> <li>Miriam Weiss, BSN., Summer Internship Program 2018, PhD student University of Maryland </li> <li>Kavisha Silva, Summer Internship Program 2018</li> <li>Natalia Iannarino, BS, Summer Internship Program 2019</li> <li>Erica Holland, Summer Internship Program 2019<br>  </li> </ul> <p><strong>Device Design for Emesis Collection During Taste Studies</strong></p> <p>Photos depict an adjustable metal device that allows for hands-free collection of taste testing expectorants in emesis bags. The device attaches to the tabletop with a clamp and has one arm holding the emesis bag open. The height of the bag from the floor is adjustable.</p> <article class="align-center media-image"> <div> <div class="visually-hidden">Image</div> <div> <img src="/sites/default/files/styles/medium__350x350_/public/Patent_SensMet4.jpg?itok=jGOcrBs5" width="350" height="467" alt="Photos depict an adjustable metal device that allows for hands-free collection of taste testing expectorants in emesis bags. The device attaches to the tabletop with a clamp and has one arm holding the emesis bag open. The height of the bag from the floor is adjustable." loading="lazy"> </div> </div> </article> <article class="align-center media-image"> <div> <div class="visually-hidden">Image</div> <div> <img src="/sites/default/files/styles/medium__350x350_/public/Patent_SensMet3.jpg?itok=ZFUIkWdD" width="350" height="467" alt="Photos depict an adjustable metal device that allows for hands-free collection of taste testing expectorants in emesis bags. The device attaches to the tabletop with a clamp and has one arm holding the emesis bag open. The height of the bag from the floor is adjustable." loading="lazy"> </div> </div> </article> <article class="align-center media-image"> <div> <div class="visually-hidden">Image</div> <div> <img src="/sites/default/files/styles/medium__350x350_/public/Patent_SensMet2.jpg?itok=QwEwB0cD" width="350" height="467" alt="Photos depict an adjustable metal device that allows for hands-free collection of taste testing expectorants in emesis bags. The device attaches to the tabletop with a clamp and has one arm holding the emesis bag open. The height of the bag from the floor is adjustable." loading="lazy"> </div> </div> </article> <article class="align-center media-image"> <div> <div class="visually-hidden">Image</div> <div> <img src="/sites/default/files/styles/medium__350x350_/public/Patent_SensMet1.jpg?itok=umMbJozW" width="350" height="467" alt="Photos depict an adjustable metal device that allows for hands-free collection of taste testing expectorants in emesis bags. The device attaches to the tabletop with a clamp and has one arm holding the emesis bag open. The height of the bag from the floor is adjustable." loading="lazy"> </div> </div> </article> </div>  </div> <div class="drawer-peek-foot"> <button class="button " aria-expanded="false" aria-label="More infomation"> <span> Read More <i class="fas fa-long-arrow-alt-down" aria-hidden="true" title="More infomation" role="img"></i> </span> <span class="hidden">Close <i class="fas fa-long-arrow-alt-up" title="long arrow up" aria-labelledby="long arrow up"></i> </span> </button> </div> </div>  </div>  </div>  </div> </div> </article> </div> </main> </div> </div> </div> <footer class="usa-footer usa-footer--big" role="contentinfo"> <div class="usa-footer__return-to-top return-to-top-stick"> <a href="#">Return to top</a> </div> <div class="usa-footer__primary-section"> <div class="usa-footer__primary-content"> <div class="grid-container"> <div class="grid-row grid-gap"> <div class="tablet:grid-col-8"> <nav class="usa-footer__nav" aria-label="Footer navigation"> <div class="grid-row 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