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type-post status-publish format-standard has-post-thumbnail hentry category-nanotechnology tag-cancer-treatment tag-chemotherapy tag-combination-therapy tag-drug-delivery tag-gold-nanoparticles tag-immunotherapy tag-lipid-based-nanoparticles tag-nanoparticles tag-nanotechnology tag-polymeric-nanoparticles tag-silver-nanoparticles tag-targeted-therapy" itemtype="https://schema.org/CreativeWork" itemscope> <div class="inside-article"> <div class="featured-image page-header-image-single "> <img width="1200" height="628" src="https://cancerscience.net/archive/wp-content/uploads/2024/09/image-20-min-scaled-e1725949546812.jpg" class="attachment-full size-full" alt="" itemprop="image" decoding="async" fetchpriority="high" /> </div> <header class="entry-header"> <h1 class="entry-title" itemprop="headline">Nanotechnology in Cancer Treatment: The Future is Now</h1> <div class="entry-meta"> <span class="posted-on"><time class="updated" datetime="2024-09-10T12:06:19+05:30" itemprop="dateModified">September 10, 2024</time><time class="entry-date published" datetime="2024-09-10T11:29:19+05:30" itemprop="datePublished">September 10, 2024</time></span> <span class="byline">by <span class="author vcard" itemprop="author" itemtype="https://schema.org/Person" itemscope><a class="url fn n" href="https://cancerscience.net/archive/author/cancerscience/" title="View all posts by cancerscience" rel="author" itemprop="url"><span class="author-name" itemprop="name">cancerscience</span></a></span></span> </div> </header> <div class="entry-content" itemprop="text"> <p><span style="font-weight: 400;">Despite the advances in the field of molecular biology, cancer continues to be one of the most significant problems in contemporary medicine due to the relatively simple and still not fully understood biological nature of cancer and its variety. Conventional treatments of cancer, including chemotherapy and radiotherapy, are notorious for being associated with hostile effects and small effectiveness, particularly at later stages of growth. However, there are new trends in the development of nanotechnologies that are changing the appearance of cancer treatment flows. Taking advantage of the characteristics of nanoparticles, new therapies are being designed that are more effective, less toxic, and therefore beneficial to the patient. The present article focuses on the advanced uses of nanotechnology in cancer therapy and the ability of this technology to revolutionize therapy for one of humanity’s top killers.</span></p> <h3><b>The Promise of Nanoparticles in Cancer Therapy</b></h3> <p><span style="font-weight: 400;">Nanoparticles are simply very small particles with sizes varying from 1 to 100 nanometers. Nanoparticles are very small in size, and they possess specific physical and chemical characteristics; thus, they can be designed to release pharmaceuticals specifically to cancer cells. This targeted delivery decreases the harm to the normal tissues, thus lessening the side effects inherent to most traditional cancer treatments.</span></p> <p><span style="font-weight: 400;">Nanoparticulate drug delivery systems have some advantages, among which one of the most important is improving the solubility and stability of the anticancer drugs. Most chemotherapeutic agents are lipophilic, and this presents problems in their preparation for administration. The drugs can be encapsulated in nanoparticles such that they enhance their bioavailability and get to the tumor site in an active state.</span></p> <h3><b>Metallic Nanoparticles: Gold and Silver</b></h3> <p><span style="font-weight: 400;">Both gold and silver nanoparticles have been used widely in cancer research because of the biocompatibility of the metal and the ease with which functional groups can be attached to them. These nanoparticles can be made in such a way that they can home in on cancer cells and deliver the desired dose of medication. Scholars have looked into the probability of increasing cancer chemotherapeutic drugs’ efficiency and creating new phototherapeutic approaches based on gold nanoparticles. Photothermal therapy utilizes nanoparticles of gold; on illumination with light, these particles convert light energy into heat, which destroys cancerous cells without damaging the adjacent healthy tissues.</span></p> <p><span style="font-weight: 400;">Silver nanoparticles, on the other hand, show different strong antimicrobial activities and have been studied with different combination therapies. Multi-modal treatments are planned by incorporating silver nanoparticles as a drug delivery system with other anticancer agents to overcome drug resistance.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Yearwise Publication Trend on <b>“<a href="https://cancerscience.net/publication-trends/index/nanotechnology" target="_blank" title="nanotechnology - yearwise publication trends">nanotechnology</a>”</b></h2> </div> </div><div class="results-container"><div class="chart-block" style="padding:15px;"> <div class="left"> <div id="results" class="results"></div> </div> <div class="right"> <div class="chart-container"><canvas id="publicationChart"></canvas></div> </div> <div class="keywordsdiv"> <div style="text-align:center;"><b>Find publication trends on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-stats"></span> </div> </div></div></div><div class="inside-article"><style> table { margin: 0 0 1.5em; 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if (!statistics || Object.keys(statistics).length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var tableHTML = `<div class='pub-scroll'> <table class='tablediv' border='1' cellspacing='0' cellpadding='0'> <tr> <th>Year</th> <th>Publication Count</th> </tr>`; Object.entries(statistics).sort(([yearA], [yearB]) => yearB - yearA).forEach(([year, count]) => { const displayCount = count === 0 ? 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Liposomes are small, round structures with phospholipid bilayers through which either hydrophilic or hydrophobic drugs can be surrounded. These virtues make them suitable for transporting a broad spectrum of anticancer drugs to the tumor site and destroying malignant cells efficiently. Contrary to cancer cells, liposomes can be functionalized with targeting ligands to increase their interaction and binding to the tumor cells, hence improving the therapeutic ratio.</span></p> <p><span style="font-weight: 400;">SLNs are spherical particles formed and stabilized with a solid lipophilic core surrounded by a phospholipid monolayer. They have interesting features like the ability to deliver a controlled amount of a drug slowly, they have a large loading capacity for the drug, and they are stable. SLNs have been investigated for the delivery of diversified chemotherapeutic agents, like paclitaxel and doxorubicin, where it has even been seen that there is increased effectiveness and reduced side effects as compared to other formulations.</span></p> <h3><b>Polymeric Nanoparticles</b></h3> <p><span style="font-weight: 400;">Polymeric nanoparticles are prepared from biocompatible and biodegradable polymers, which makes them ideal for long-term and regulated release of the drug. These nanoparticles can be designed to be sensitive to particular changes in the physiological environment, for instance, pH or the activity of a certain enzyme, and the drug will only be released at the tumor site. This specific distribution system minimizes the general toxic effects when intervening with the treatment’s curative effects.</span></p> <p><span style="font-weight: 400;">Several studies have shown that polymeric nanoparticles can be effective in combating this issue of MDRA, which is a major concern in cancer treatments. Polymeric nanoparticles can be </span><span style="font-weight: 400;">designed to co-deliver both chemotherapeutic drugs and gene-silencing agents that, when internalized by the cancer cells, will block the drug efflux mechanism and, at the same time, induce cancer cell apoptosis thus overcoming drug-resistant tumors.</span></p> <h3><b>Nanoparticle-Based Combination Therapies</b></h3> <p><span style="font-weight: 400;">The use of more than one therapeutic modality at the same time or using products that have established therapeutic properties is regarded as combination therapy, and this strategy occupies an important position in the current model of cancer treatment. Multi-drug encapsulation is also possible using nanoparticles, due to their ability to release the drugs with different modes of action all at once. This approach goes further to improve the effectiveness of the therapy and lessen the chances of medication resistance.</span></p> <p><span style="font-weight: 400;">A case in point is the employment of nanoparticles for the co-delivery of docetaxel as well as doxorubicin, two effective chemotherapeutic drugs. When these drugs are incorporated in a single nanoparticle, the researchers have found a way of achieving the desired synergistic ratio, hence enhancing the targeting of tumors and minimizing the side effects. Also, targeted drug delivery can be attained through the incorporation of targeting ligands into the nanoparticles, thus increasing the nanoparticle’s specificity to the cancer cells, which is very convenient since it ensures that the therapeutic agents are delivered only to the intended area.</span></p> <h3><b>Nanoparticles in Immunotherapy</b></h3> <p><span style="font-weight: 400;">Immunotherapy is one of the developing approaches in the treatment of cancer that involves the use of the immune system of the body to identify and eliminate cancerous cells. Immunotherapy can be made more effective by the use of nanoparticles to boost the delivery and presentation of the antigens to the immune cells. For example, they can be designed to deliver tumor antigens and adjuvants, which trigger a powerful response against cancer cells.</span></p> <p><span style="font-weight: 400;">The innovations in cancer treatment have involved designing nanoparticles that can alter the tumor microenvironment in a manner that is favorable for the infiltration and effectiveness of immune cells. Nanoparticle-based immunotherapies take strategic approaches of targeting immune checkpoints to release immune-stimulatory agents to reverse the immunosuppressive tumor microenvironment of cancer to improve the efficacy of cancer immunotherapy.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Recent Publications on <b>“<a href="https://cancerscience.net/recent-publications/index/nanotechnology" target="_blank" rel="noopener" title="nanotechnology - yearwise publication list">nanotechnology</a>”</b></h2> </div> </div> <div class="pb-main"><div class="article-scroll"><div id="results_recent" class="results"></div></div><div class="keywordsdiv" style="margin: 0px 15px;margin-top:20px;"> <div style="text-align:center;"><b>Find publications on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-papers"></span> </div></div></div><div class="inside-article"> <style> .pb-main{ border: solid 1px #ccc; border-top: none; margin-bottom: 20px; padding-bottom: 25px; background:#fff; } .author-main { border: solid 1px #ccc; border-top: none; margin-bottom: 20px; padding-bottom: 25px; background:#fff; } .publication-block { padding: 10px; margin-bottom: 10px; background-color: #f9f9f9; text-align: left; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .publication-block h3 { margin: 0 0 10px; color: #000!important; } .publication-block a { font-size: 16px !important; line-height: 1em; font-weight: 600; text-transform: none; color: #000; padding: 0px; } .publication-block a:hover{ color: #227cdc; text-decoration:underline; } .article-scroll { max-height: 445px; overflow-y: auto; overflow-x: hidden; } ::-webkit-scrollbar-track { -webkit-box-shadow: inset 0 0 6px rgba(0,0,0,0.3); background-color: #efefef; border-radius:30px; } ::-webkit-scrollbar { width: 6px; background-color: #efefef; border-radius:30px; } ::-webkit-scrollbar-thumb { background-color: #ababab; border-radius:30px; } .publication-block p { margin-bottom: .5em; font-size: 15px; color: #000; } h3 { font-size: 18px !important; margin-bottom: 20px; line-height: 1.2em; font-weight: 600; text-transform: none; } a { padding: 5px; color: #a71c49; } #keyword-papers{ margin-top: 20px; text-align: center; } </style> <script> function displayResults_recent(papers) { var resultsContainer = document.getElementById('results_recent'); if (!papers || papers.length === 0) { resultsContainer.innerHTML = '<p>No recent publications found.</p>'; return; } papers.forEach(paper => { var publicationBlock = document.createElement('div'); publicationBlock.className = 'publication-block'; var publicationHTML = ` <div style="margin-bottom: 10px;line-height: 24px;"><a href="${paper.url}" target="_blank" title="${paper.title}">${paper.title}</a></div> <p><strong>Issue Release:</strong> ${paper.publishedDate}</p> `; publicationBlock.innerHTML = publicationHTML; resultsContainer.appendChild(publicationBlock); }); } function displayKeywordPapers(keywords) { var resultsContainer = document.getElementById('keyword-papers'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach((key, index) => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://cancerscience.net/recent-publications/index/${key_replace}" target="_blank" title="${key} - publication list">${key}</a>`; if (index < keywords.length - 1) { keywordHTML += ', '; } }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var recent_papers = [ { "title": "An overview of the contemporary diagnosis and management approaches for anaplastic thyroid carcinoma.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38946831", "publishedDate": "2024" }, { "title": "Bio-gel nanoarchitectonics in tissue engineering.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38953604", "publishedDate": "2024" }, { "title": "Recent advances in gene delivery nanoplatforms based on spherical nucleic acids.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38951806", "publishedDate": "2024" }, { "title": "Nanomaterials in plant physiology: main effects in normal and under temperature stress.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38838991", "publishedDate": "2024" }, { "title": "The draft genome of Nitzschia closterium f. minutissima and transcriptome analysis reveals novel insights into diatom biosilicification.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38840265", "publishedDate": "2024" }, { "title": "Adsorption and solar light activity of noble metal adatoms (Au and Zn) on Fe(111) surface: a first-principles study.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38845366", "publishedDate": "2024" }, { "title": "The influence of Au-based nanoparticles on some physiological, biochemical and molecular characteristics of wheat plants during low temperature hardening.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38878389", "publishedDate": "2024" }, { "title": "Starch-based biodegradable films amended with nano-starch and tannic acid-coated nano-starch exhibit enhanced mechanical and functional attributes with antimicrobial activity.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38876723", "publishedDate": "2024" }, { "title": "Magnetic nanostructured agents for the mitigation of mycotoxins and cyanotoxins in the food chain.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38870813", "publishedDate": "2024" }, { "title": "Metal and metal oxide nanoparticles-induced reactive oxygen species: Phytotoxicity and detoxification mechanisms in plant cell.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38889532", "publishedDate": "2024" }, { "title": "Advancements in nanomedicine: Precision delivery strategies for male pelvic malignancies - Spotlight on prostate and colorectal cancer.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38788248", "publishedDate": "2024" }, { "title": "Bionanocomposites comprising mesoporous metal organic framework (ZIF-8) phytofabricated with Allium sativum as alternative nanomaterials to combat antimicrobial drug resistance.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38767741", "publishedDate": "2024" }, { "title": "Antibiotic resistance and Nanotechnology: A narrative review.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38871198", "publishedDate": "2024" }, { "title": "Therapeutic potential of Phycocyanin in gastrointestinal cancers and related disorders.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38874869", "publishedDate": "2024" }, { "title": "Nanomaterial-related hemoglobin-based oxygen carriers, with emphasis on liposome and nano-capsules, for biomedical applications: current status and future perspectives.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38880905", "publishedDate": "2024" }, { "title": "RNA nanotechnology on the horizon: Self-assembly, chemical modifications, and functional applications.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38889473", "publishedDate": "2024" }, { "title": "A detailed study of the electronic and optical properties of germanium nanotubes.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38884298", "publishedDate": "2024" }, { "title": "In vitro biological evaluation of a novel folic acid-targeted receptor quantum dot-\u03b2-cyclodextrin carrier for C-2028 unsymmetrical bisacridine in the treatment of human lung and prostate cancers.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38888724", "publishedDate": "2024" }, { "title": "Hydrochars as a bio-based adsorbent for heavy metals removal: A review of production processes, adsorption mechanisms, kinetic models, regeneration and reusability of hydrochar.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38897477", "publishedDate": "2024" }, { "title": "Clinical translation of nanomedicine with integrated digital medicine and machine learning interventions.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38897022", "publishedDate": "2024" } ]; var keywordsArray = ["Nanotechnology","Cancer treatment","Nanoparticles","Drug delivery","Chemotherapy","Immunotherapy","Targeted therapy","Gold nanoparticles","Silver nanoparticles","Lipid-based nanoparticles","Polymeric nanoparticles","Combination therapy"]; displayResults_recent(recent_papers); displayKeywordPapers(keywordsArray); </script></p> <h3><b>Challenges and Future Directions</b></h3> <p><span style="font-weight: 400;">However, there are several challenges regarding the clinical application of nanoparticle-mediated cancer therapeutic strategies. The biology of the cancer is relatively intricate, combined with the difficulties that arise when designing a standard regimen given the differences in the patient’s response to the treatment cycles. Furthermore, the chronic safety and genotoxicity properties of nanoparticles need to be assessed through extensive in vitro and in vivo research tests.</span></p> <p><span style="font-weight: 400;">In future investigations, the details of the nanoparticle design and its sentimental action will be on the rise to enhance the targeting ability and the therapeutic action of the nanoparticles. Combined with image-guided therapies such as nanoparticle-based therapies, patients can have a real-time outlook on the progression of the disease and make desirable changes in the course of the therapy. Furthermore, researchers have identified the possibilities of using multifunctional nanoparticles for the targeted delivery of drugs, genes, and imaging agents for cancer therapy.</span></p> <h3><b>Conclusion</b></h3> <p><span style="font-weight: 400;">Nanotechnology has the potential to dramatically transform the approach to cancer care through the application of advanced therapies that are precise, effective, and tailored to an individual’s needs. The characteristics of nanoparticles have the potential to accurately target the therapeutic agents to the affected areas with reduced side effects and improved results. As discoveries for new uses for nanoparticles are made and applications are fine-tuned, it is envisioned that targeted cancer therapies involving nanoparticles would be one of the basic facets of most comprehensive cancer management for patients around the globe.</span></p> <p></p> <h3><b>References</b></h3> <ol> <li> <div class="citation-text">Neha Desai, Momin M, Khan T, Gharat S, Ningthoujam RS, Omri A. <a href="https://pubmed.ncbi.nlm.nih.gov/33793359/">Metallic nanoparticles as drug delivery system for the treatment of cancer.</a> Expert Opin Drug Deliv. 2021 Sep;18(9):1261-1290. doi: 10.1080/17425247.2021.1912008. Epub 2021 Apr 14. PMID: 33793359.</div> </li> <li> <div class="citation-text">Yao Y, Zhou Y, Liu L, Xu Y, Chen Q, Wang Y, Wu S, Deng Y, Zhang J, Shao A. <a href="https://pubmed.ncbi.nlm.nih.gov/32974385/">Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance.</a> Front Mol Biosci. 2020 Aug 20;7:193. doi: 10.3389/fmolb.2020.00193. 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PMID: 32907621; PMCID: PMC7488324.</div> <div class="citation-actions"></div> </li> </ol> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Top Experts on “<b style="color:#000;font-size:22px;">nanotechnology</b>“</h2> </div> </div><div class="author-main"><div id="results_author"></div><div style="text-align: center;"><a class="register-button" href="https://cancerscience.net/expert-search" target="_blank" rel="noopener">Find experts on any field</a></div></div><div class="inside-article" style="background: none;border: none;box-shadow: none;margin-top: -70px;"> <style> .author-block { padding: 15px; margin-bottom: 10px; text-align: left; font-size: 15px; line-height: 1.2; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .author-block h3 { margin: 0 0 10px; color: #227cdc; } .author-block p { margin: 5px 0; } .author-b { display: flex; justify-content: space-between; flex-wrap: wrap; margin-bottom:10px; } .author-b .ainfo { flex: 1 1 30%; box-sizing: border-box; text-align: left; background: #dcdcdc; padding: 7px 14px; border-radius: 5px; margin-top: 3px; margin-right: 10px; } @media (max-width: 768px) { .author-b .ainfo { flex: 1 1 100%; margin: 10px 0; } } </style> <script> function displayResults_author(authors) { var resultsContainer = document.getElementById('results_author'); resultsContainer.innerHTML = ''; if (!authors || Object.keys(authors).length === 0) { resultsContainer.innerHTML = '<p>No authors found.</p>'; return; } Object.values(authors).slice(0, 10).forEach(author => { var authorBlock = document.createElement('div'); authorBlock.className = 'author-block'; var author_name=author.name; let key_replace = author_name.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); var authorHTML = ` <h3><a href="https://cancerscience.net/author/index/${key_replace}\/${author.aid}" target="_blank" title="${author.name}">${author.name}</a></h3> <div class="author-b"> <div class="ainfo"><strong>H-Index:</strong> ${author.hindex}</div> <div class="ainfo"><strong>Publication Count:</strong> ${author.paper_count}</div> <div class="ainfo"><strong>Citation Count:</strong> ${author.citation_count}</div> </div> <p><strong>Affiliation:</strong> ${author.affiliation}</p> `; authorBlock.innerHTML = authorHTML; resultsContainer.appendChild(authorBlock); }); } function displayKeywordAuthors(keywords) { var resultsContainer = document.getElementById('keyword-authors'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach(key => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://cancerscience.net/expert-search/index/${key_replace}" target="_blank" title="${key}">${key}</a>`; }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var authors_data = { "1wmvK4wBWBy50K-r-HH0": { "aid": "1wmvK4wBWBy50K-r-HH0", "name": "O. 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