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Sebai</title> <meta name="description" content="Search results for: Essia Sebai"> <meta name="keywords" content="Essia Sebai"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Essia Sebai"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 8</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Essia Sebai</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Nematocidal Effects of Laurus Nobilis Essential Oil against Gastrointestinal Nematodes.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Essia%20Sebai">Essia Sebai</a>, <a href="https://publications.waset.org/abstracts/search?q=Amel%20Abidi"> Amel Abidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hayet%20benyeddem"> Hayet benyeddem</a>, <a href="https://publications.waset.org/abstracts/search?q=Akkari%20Hafidh"> Akkari Hafidh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Herbal extracts are of particular interest to the drug industry; essential oil with significant anthelmintic activity has the potential to be used as an alternative to conventional chemical drugs. In the present study, we describe the chemical profile of Laurus nobilis essential oil (EO), the in vitro anthelmintic activity of laurel oil against Haemonchus contortus and its in vivo anthelmintic effect against the murine helminth parasite model Heligmosomoides polygyrus. The chromatographic profile of L. nobilis (EO) extracted from the leaves of L. nobilis has shown the presence of monoterpenes 1,8-cineol (Eucalyptol) (29.47%), D-Limonène (18.51%) and Linalool (10.84%) in high fractions. The in vitro anthelmintic potential was expressed by an ovicidal effect against H. contortus egg hatching with an inhibition value of 3.23 mg/mL and 87.5% of immobility of adult worms after 8 hours of exposure to 8 mg/mL of L. nobilis EO. Regarding the in vivo anthelmintic potential, L. nobilis (EO) at 2400 mg/kg completely eliminated the egg output of H. polygyrus after seven days of oral treatment, together with a 79.2% of reduction in total worm counts. Based on the obtained funding, L. nobilis EO showed promising in vitro and in vivo anthelmintic capacities against gastrointestinal parasites. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lauris%20nobilis" title="lauris nobilis">lauris nobilis</a>, <a href="https://publications.waset.org/abstracts/search?q=anthelmintic" title=" anthelmintic"> anthelmintic</a>, <a href="https://publications.waset.org/abstracts/search?q=haemonchus" title=" haemonchus"> haemonchus</a>, <a href="https://publications.waset.org/abstracts/search?q=pylogyrus" title=" pylogyrus"> pylogyrus</a> </p> <a href="https://publications.waset.org/abstracts/161804/nematocidal-effects-of-laurus-nobilis-essential-oil-against-gastrointestinal-nematodes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161804.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">104</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Microstructure and Excess Conductivity of Bulk, Ag-Added FeSe Superconductors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michael%20Koblischka">Michael Koblischka</a>, <a href="https://publications.waset.org/abstracts/search?q=Yassine%20Slimani"> Yassine Slimani</a>, <a href="https://publications.waset.org/abstracts/search?q=Thomas%20%20Karwoth"> Thomas Karwoth</a>, <a href="https://publications.waset.org/abstracts/search?q=Anjela%20Koblischka-Veneva"> Anjela Koblischka-Veneva</a>, <a href="https://publications.waset.org/abstracts/search?q=Essia%20%20Hannachi"> Essia Hannachi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> On bulk FeSe superconductors containing different additions of Ag, a thorough investigation of the microstructures was performed using optical microscopy, SEM and TEM. The electrical resistivity was measured using four-point measurements in the temperature range 2 K ≤ T ≤ 150 K. The data obtained are analyzed in the framework of the excess conductivity approach using the Aslamazov-Larkin (AL) model. The investigated samples comprised of five distinct fluctuation regimes, namely short-wave (SWF), onedimensional (1D), two-dimensional (2D), three-dimensional (3D), and critical (CR) fluctuation regimes. The coherence length along the c-axis at zero-temperature (ξc(0)), the lower and upper critical magnetic fields (Bc1 and Bc2), the critical current density (Jc) and numerous other superconducting parameters were estimated with respect to the Ag content in the samples. The data reveal a reduction of the resistivity and a strong decrease of ξc(0) when doping the 11-samples with silver. The optimum content of the Ag-addition is found at 4 wt.-% Ag, yielding the highest critical current density. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=iron-based%20superconductors" title="iron-based superconductors">iron-based superconductors</a>, <a href="https://publications.waset.org/abstracts/search?q=FeSe" title=" FeSe"> FeSe</a>, <a href="https://publications.waset.org/abstracts/search?q=Ag-addition" title=" Ag-addition"> Ag-addition</a>, <a href="https://publications.waset.org/abstracts/search?q=excess%20conductivity" title=" excess conductivity"> excess conductivity</a>, <a href="https://publications.waset.org/abstracts/search?q=microstructure" title=" microstructure"> microstructure</a> </p> <a href="https://publications.waset.org/abstracts/120148/microstructure-and-excess-conductivity-of-bulk-ag-added-fese-superconductors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/120148.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">145</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Dimensionality and Superconducting Parameters of YBa2Cu3O7 Foams </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michael%20Koblischka">Michael Koblischka</a>, <a href="https://publications.waset.org/abstracts/search?q=Anjela%20%20Koblischka-Veneva"> Anjela Koblischka-Veneva</a>, <a href="https://publications.waset.org/abstracts/search?q=XianLin%20%20Zeng"> XianLin Zeng</a>, <a href="https://publications.waset.org/abstracts/search?q=Essia%20%20Hannachi"> Essia Hannachi</a>, <a href="https://publications.waset.org/abstracts/search?q=Yassine%20%20Slimani"> Yassine Slimani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Superconducting foams of YBa2Cu3O7 (abbreviated Y-123) were produced using the infiltration growth (IG) technique from Y2BaCuO5 (Y-211) foams. The samples were investigated by SEM (scanning electron microscopy) and electrical resistivity measurements. SEM observations indicated the specific microstructure of the foam struts with numerous tiny Y-211 particles (50-100 nm diameter) embedded in channel-like structures between the Y-123 grains. The investigation of the excess conductivity of different prepared composites was analyzed using Aslamazov-Larkin (AL) model. The investigated samples comprised of five distinct fluctuation regimes, namely short-wave (SWF), one-dimensional (1D), two-dimensional (2D), three-dimensional (3D), and critical (CR) fluctuations regimes. The coherence length along the c-axis at zero-temperature (ξc(0)), lower and upper critical magnetic fields (Bc1 and Bc2), critical current density (Jc) and numerous other superconducting parameters were estimated from the data. The analysis reveals that the presence of the tiny Y-211 particles alters the excess conductivity and the fluctuation behavior observed in standard YBCO samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Excess%20conductivity" title="Excess conductivity">Excess conductivity</a>, <a href="https://publications.waset.org/abstracts/search?q=Foam" title=" Foam"> Foam</a>, <a href="https://publications.waset.org/abstracts/search?q=Microstructure" title=" Microstructure"> Microstructure</a>, <a href="https://publications.waset.org/abstracts/search?q=Superconductor%20YBa2Cu3Oy" title=" Superconductor YBa2Cu3Oy "> Superconductor YBa2Cu3Oy </a> </p> <a href="https://publications.waset.org/abstracts/123872/dimensionality-and-superconducting-parameters-of-yba2cu3o7-foams" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/123872.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">169</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Enhancement of Rice Straw Composting Using UV Induced Mutants of Penicillium Strain</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T.%20N.%20M.%20El%20Sebai">T. N. M. El Sebai</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20A.%20Khattab"> A. A. Khattab</a>, <a href="https://publications.waset.org/abstracts/search?q=Wafaa%20M.%20Abd-El%20Rahim"> Wafaa M. Abd-El Rahim</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Moawad"> H. Moawad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Fungal mutant strains have produced cellulase and xylanase enzymes, and have induced high hydrolysis with enhanced of rice straw. The mutants were obtained by exposing Penicillium strain to UV-light treatments. Screening and selection after treatment with UV-light were carried out using cellulolytic and xylanolytic clear zones method to select the hypercellulolytic and hyperxylanolytic mutants. These mutants were evaluated for their cellulase and xylanase enzyme production as well as their abilities for biodegradation of rice straw. The mutant 12 UV/1 produced 306.21% and 209.91% cellulase and xylanase, respectively, as compared with the original wild type strain. This mutant showed high capacity of rice straw degradation. The effectiveness of tested mutant strain and that of wild strain was compared in relation to enhancing the composting process of rice straw and animal manures mixture. The results obtained showed that the compost product of inoculated mixture with mutant strain (12 UV/1) was the best compared to the wild strain and un-inoculated mixture. Analysis of the composted materials showed that the characteristics of the produced compost were close to those of the high quality standard compost. The results obtained in the present work suggest that the combination between rice straw and animal manure could be used for enhancing the composting process of rice straw and particularly when applied with fungal decomposer accelerating the composting process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=rice%20straw" title="rice straw">rice straw</a>, <a href="https://publications.waset.org/abstracts/search?q=composting" title=" composting"> composting</a>, <a href="https://publications.waset.org/abstracts/search?q=UV%20mutants" title=" UV mutants"> UV mutants</a>, <a href="https://publications.waset.org/abstracts/search?q=Penicillium" title=" Penicillium"> Penicillium</a> </p> <a href="https://publications.waset.org/abstracts/7467/enhancement-of-rice-straw-composting-using-uv-induced-mutants-of-penicillium-strain" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7467.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">283</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Hydrodynamic Modeling of the Hydraulic Threshold El Haouareb</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sebai%20Amal">Sebai Amal</a>, <a href="https://publications.waset.org/abstracts/search?q=Massuel%20Sylvain"> Massuel Sylvain</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Groundwater is the key element of the development of most of the semi-arid areas where water resources are increasingly scarce due to an irregularity of precipitation, on the one hand, and an increasing demand on the other hand. This is the case of the watershed of the Central Tunisia Merguellil, object of the present study, which focuses on an implementation of an underground flows hydrodynamic model to understand the recharge processes of the Kairouan’s plain groundwater by aquifers boundary through the hydraulic threshold of El Haouareb. The construction of a conceptual geological 3D model by the Hydro GeoBuilder software has led to a definition of the aquifers geometry in the studied area thanks to the data acquired by the analysis of geologic sections of drilling and piezometers crossed shells partially or in full. Overall analyses of the piezometric Chronicles of different piezometers located at the level of the dam indicate that the influence of the dam is felt especially in the aquifer carbonate which confirms that the dynamics of this aquifer are highly correlated to the dam’s dynamic. Groundwater maps, high and low-water dam, show a flow that moves towards the threshold of El Haouareb to the discharge of the waters of Ain El Beidha discharge towards the plain of Kairouan. Software FEFLOW 5.2 steady hydrodynamic modeling to simulate the hydraulic threshold at the level of the dam El Haouareb in a satisfactory manner. However, the sensitivity study to the different parameters shows equivalence problems and a fix to calibrate the limestones’ permeability. This work could be improved by refining the timing steady and amending the representation of limestones in the model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hydrodynamic%20modeling" title="Hydrodynamic modeling">Hydrodynamic modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=lithological%20modeling" title=" lithological modeling"> lithological modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=hydraulic" title=" hydraulic"> hydraulic</a>, <a href="https://publications.waset.org/abstracts/search?q=semi-arid" title=" semi-arid"> semi-arid</a>, <a href="https://publications.waset.org/abstracts/search?q=merguellil" title=" merguellil"> merguellil</a>, <a href="https://publications.waset.org/abstracts/search?q=central%20Tunisia" title=" central Tunisia"> central Tunisia</a> </p> <a href="https://publications.waset.org/abstracts/27992/hydrodynamic-modeling-of-the-hydraulic-threshold-el-haouareb" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27992.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">764</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> In vitro Inhibitory Action of an Aqueous Extract of Carob on the Release of Myeloperoxidase by Human Neutrophils</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kais%20Rtibi">Kais Rtibi</a>, <a href="https://publications.waset.org/abstracts/search?q=Slimen%20Selmi"> Slimen Selmi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jamel%20El-Benna"> Jamel El-Benna</a>, <a href="https://publications.waset.org/abstracts/search?q=Lamjed%20Marzouki"> Lamjed Marzouki</a>, <a href="https://publications.waset.org/abstracts/search?q=Hichem%20Sebai"> Hichem Sebai </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Myeloperoxidase (MPO) is a hemic enzyme found in high concentrations in the primary neutrophils granules. In addition to its peroxidase activity, it has a chlorination activity, using hydrogen peroxide and chloride ions to form hypochlorous acid, a strong oxidant, capable of chlorinating molecules. Bioactive compounds contained in medicinal plants could limit the action of this enzyme to reduce the reactive oxygen species production and its chlorination activity. The purpose of this study is to evaluate the effect of the carob aqueous extract (CAE) on the release of MPO by human neutrophils in vitro and its activity following stimulation of these cells by PMA. Methods: Neutrophils were isolated by simple sedimentation using the Dextran/Ficoll method. After stimulation with phorbol 12-myristate 13-acetate (PMA), neutrophils release the MPO by degranulation. The effect of CAE on the release of MPO was analyzed by the Western blot technique, while, its activity was determined by biochemical method using the method of 3,3', 5,5'- Tetramethylbenzidine (TMB) and hydrogen peroxide. The data were expressed as mean ± SEM. Results: The carob aqueous extract causes a decrease in MPO quantity and activity in a concentration-dependent manner which leads to a reduction of the production of the ROS (reactive oxygen species) and the protection of the molecules against oxidation and chlorination mechanisms. Conclusion: Thanks to its richness in bioactive compounds, the aqueous extract of carob could limit the development of damages related to the uncontrolled activity of MPO. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carob" title="carob">carob</a>, <a href="https://publications.waset.org/abstracts/search?q=MPO" title=" MPO"> MPO</a>, <a href="https://publications.waset.org/abstracts/search?q=myeloperoxidase" title=" myeloperoxidase"> myeloperoxidase</a>, <a href="https://publications.waset.org/abstracts/search?q=neutrophils" title=" neutrophils"> neutrophils</a>, <a href="https://publications.waset.org/abstracts/search?q=PMA" title=" PMA"> PMA</a>, <a href="https://publications.waset.org/abstracts/search?q=phorbol%2012-myristate%2013-acetate" title=" phorbol 12-myristate 13-acetate"> phorbol 12-myristate 13-acetate</a> </p> <a href="https://publications.waset.org/abstracts/96290/in-vitro-inhibitory-action-of-an-aqueous-extract-of-carob-on-the-release-of-myeloperoxidase-by-human-neutrophils" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96290.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">157</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Implication of Oxidative Stress and Intracellular Mediators in the Protective Effect of Artemisia campestris against Aspirin-Induced Gastric Lesions in Rat Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hichem%20Sebai">Hichem Sebai</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Amine%20Jabri"> Mohamed Amine Jabri</a>, <a href="https://publications.waset.org/abstracts/search?q=Kais%20Rtibi"> Kais Rtibi</a>, <a href="https://publications.waset.org/abstracts/search?q=Haifa%20Tounsi"> Haifa Tounsi</a>, <a href="https://publications.waset.org/abstracts/search?q=Lamjed%20Marzouki"> Lamjed Marzouki</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Artemisia campestris has been widely used in Tunisian traditional medicine for its health beneficial effects. However, the present study aims at evaluating the antiulcer effects of Artemisia campestris aqueous extract (ACAE) as well as the mechanism of action involved in such gastroprotection. In this respect, male Wistar rats were divided into seven groups: control, aspirin (ASPR), ASPR + various doses of ACAE (100, 200 and 400 mg/kg, b.w.), ASPR+ famotidine and ASPR+ caffeic acid. Animals were pre-treated with ACAE extract during 10 days. We firstly showed that aspirin administration was accompanied by an oxidative stress status assessed by an increase of malondialdehyde (MDA) level, a decrease of sulfhydryl -(SH) groups content and depletion of antioxidant enzyme activities such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). Pre-treatment with ACAE protected against aspirin-induced gastric oxidative stress. More importantly, aspirin administration increased plasma and tissue hydrogen peroxide (H₂O₂), free iron and calcium levels while the ACAE pre-treatment reversed all aspirin-induced intracellular mediators disturbance. The results of the present study clearly indicated that AEAC gastroprotection might be related, at least in part, to its antioxidant properties as well as to various gastric mucosal defense mechanisms, including the protection of gastric sulfhydryls and an opposite effect on some intracellular mediators such as free iron, hydrogen peroxide, and calcium. However, our data confirm the use of Artemisia campestris extracts in the Tunisian traditional folk medicine for the treatment of gastrointestinal diseases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=gastric%20ulcer" title="gastric ulcer">gastric ulcer</a>, <a href="https://publications.waset.org/abstracts/search?q=Artemisia%20campestris" title=" Artemisia campestris"> Artemisia campestris</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20stress" title=" oxidative stress"> oxidative stress</a>, <a href="https://publications.waset.org/abstracts/search?q=sulfhydryl%20groups" title=" sulfhydryl groups"> sulfhydryl groups</a>, <a href="https://publications.waset.org/abstracts/search?q=Fenton%20reaction" title=" Fenton reaction"> Fenton reaction</a>, <a href="https://publications.waset.org/abstracts/search?q=rat" title=" rat"> rat</a> </p> <a href="https://publications.waset.org/abstracts/108034/implication-of-oxidative-stress-and-intracellular-mediators-in-the-protective-effect-of-artemisia-campestris-against-aspirin-induced-gastric-lesions-in-rat-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/108034.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">146</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Antioxydant Properties and Gastroprotective Effect of Rosa canina Aqueous Extract against Alcohol-Induced Ulceration and Oxidative Stress in Rat Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Sebai">H. Sebai</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Jabria"> M. A. Jabria</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Wannes"> D. Wannes</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Tounsi"> H. Tounsi</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Marzouki"> L. Marzouki</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We aimed in the present study to investigate the protective effects of Tunisian Rosa canina aqueous extract (RCAE) against ethanol-induced gastric ulceration and oxidative stress in a rat model. In this respect, adult male Wistar rats were used and divided into six groups of ten each: control, EtOH, EtOH plus various doses of RCAE, EtOH plus famotidine and EtOH + gallic acid. Phytochemical and biochemical analysis were performed using colorimetric methods. We found that RCAE is rich in total polyphenols, total flavonoids, and condensed tannins, and exhibited an importance in vitro antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. In vivo, the results showed that oral administration of EtOH caused macroscopic and histological changes in gastric mucosa. These injuries are accompanied by an oxidative stress status as assessed by an increase of lipid peroxidation as well as a decrease of antioxidant enzyme activities such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). Alcohol intoxication also induced intracellular mediators deregulation as assessed by an increase of hydrogen peroxide (H2O2), calcium and free iron levels in gastric mucosa. More, importantly, RCAE pretreatment reversed all macroscopic, histological and biochemical changes induced by EtOH administration. In conclusion, we suggest that RCAE has potent protective effects on acute ethanol-induced gastric ulceration related in part in part its antioxidant properties and its opposite effect on intracellular mediators. Indeed, Rosa canina can be offered as a food additive to protect against alcohol consumption-induced gastric and oxidative damage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alcohol" title="alcohol">alcohol</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20properties" title=" antioxidant properties"> antioxidant properties</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20additive" title=" food additive"> food additive</a>, <a href="https://publications.waset.org/abstracts/search?q=gastric%20ulceration" title=" gastric ulceration"> gastric ulceration</a>, <a href="https://publications.waset.org/abstracts/search?q=rat%20model" title=" rat model"> rat model</a>, <a href="https://publications.waset.org/abstracts/search?q=Rosa%20canina" title=" Rosa canina"> Rosa canina</a> </p> <a href="https://publications.waset.org/abstracts/98978/antioxydant-properties-and-gastroprotective-effect-of-rosa-canina-aqueous-extract-against-alcohol-induced-ulceration-and-oxidative-stress-in-rat-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98978.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">197</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET 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