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人类蛋白质组计划 - 维基百科,自由的百科全书

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href="/w/index.php?title=Special:%E5%88%9B%E5%BB%BA%E8%B4%A6%E6%88%B7&amp;returnto=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" title="我们推荐您创建账号并登录,但这不是强制性的"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>创建账号</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E7%94%A8%E6%88%B7%E7%99%BB%E5%BD%95&amp;returnto=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" title="建议你登录,尽管并非必须。[o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>登录</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> 未登录编辑者的页面 <a href="/wiki/Help:%E6%96%B0%E6%89%8B%E5%85%A5%E9%97%A8" aria-label="了解有关编辑的更多信息"><span>了解详情</span></a> </div> <div class="vector-menu-content"> <ul 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class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#历史"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>历史</span> </div> </a> <ul id="toc-历史-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-项目和工作组" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#项目和工作组"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>项目和工作组</span> </div> </a> <ul id="toc-项目和工作组-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-计算资源" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#计算资源"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>计算资源</span> </div> </a> <ul id="toc-计算资源-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-现状" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#现状"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>现状</span> </div> </a> <ul id="toc-现状-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-参阅" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#参阅"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>参阅</span> </div> </a> <ul id="toc-参阅-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-参考资料" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#参考资料"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>参考资料</span> </div> </a> <ul id="toc-参考资料-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部链接" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部链接"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>外部链接</span> </div> </a> <ul id="toc-外部链接-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">人类蛋白质组计划</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。8种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-8" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">8种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Projecte_Proteoma_Hum%C3%A0" title="Projecte Proteoma Humà – 加泰罗尼亚语" lang="ca" hreflang="ca" data-title="Projecte Proteoma Humà" data-language-autonym="Català" data-language-local-name="加泰罗尼亚语" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Human_Proteome_Project" title="Human Proteome Project – 英语" lang="en" hreflang="en" data-title="Human Proteome Project" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Proyecto_proteoma_humano" title="Proyecto proteoma humano – 西班牙语" lang="es" hreflang="es" data-title="Proyecto proteoma humano" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%D8%B1%D9%88%DA%98%D9%87_%D9%BE%D8%B1%D9%88%D8%AA%D8%A6%D9%88%D9%85_%D8%A7%D9%86%D8%B3%D8%A7%D9%86" title="پروژه پروتئوم انسان – 波斯语" lang="fa" hreflang="fa" data-title="پروژه پروتئوم انسان" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Projet_prot%C3%A9ome_humain" title="Projet protéome humain – 法语" lang="fr" hreflang="fr" data-title="Projet protéome humain" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Progetto_Proteoma_Umano" title="Progetto Proteoma Umano – 意大利语" lang="it" hreflang="it" data-title="Progetto Proteoma Umano" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9F%D1%80%D0%BE%D0%B5%D0%BA%D1%82_%C2%AB%D0%9F%D1%80%D0%BE%D1%82%D0%B5%D0%BE%D0%BC_%D1%87%D0%B5%D0%BB%D0%BE%D0%B2%D0%B5%D0%BA%D0%B0%C2%BB" title="Проект «Протеом человека» – 俄语" lang="ru" hreflang="ru" data-title="Проект «Протеом человека»" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/%C4%B0nsan_Proteom_Projesi" title="İnsan Proteom Projesi – 土耳其语" lang="tr" hreflang="tr" data-title="İnsan Proteom Projesi" data-language-autonym="Türkçe" data-language-local-name="土耳其语" class="interlanguage-link-target"><span>Türkçe</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3813754#sitelinks-wikipedia" title="编辑跨语言链接" class="wbc-editpage">编辑链接</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="命名空间"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" title="浏览条目正文[c]" accesskey="c"><span>条目</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" rel="discussion" title="关于此页面的讨论[t]" accesskey="t"><span>讨论</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="更改语言变体" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">不转换</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-varlang-0" class="selected ca-variants-zh mw-list-item"><a href="/zh/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh" hreflang="zh"><span>不转换</span></a></li><li id="ca-varlang-1" class="ca-variants-zh-Hans mw-list-item"><a href="/zh-hans/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hans" hreflang="zh-Hans"><span>简体</span></a></li><li id="ca-varlang-2" class="ca-variants-zh-Hant mw-list-item"><a href="/zh-hant/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hant" hreflang="zh-Hant"><span>繁體</span></a></li><li id="ca-varlang-3" class="ca-variants-zh-Hans-CN mw-list-item"><a href="/zh-cn/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hans-CN" hreflang="zh-Hans-CN"><span>大陆简体</span></a></li><li id="ca-varlang-4" class="ca-variants-zh-Hant-HK mw-list-item"><a href="/zh-hk/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hant-HK" hreflang="zh-Hant-HK"><span>香港繁體</span></a></li><li id="ca-varlang-5" class="ca-variants-zh-Hant-MO mw-list-item"><a href="/zh-mo/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hant-MO" hreflang="zh-Hant-MO"><span>澳門繁體</span></a></li><li id="ca-varlang-6" class="ca-variants-zh-Hans-MY mw-list-item"><a href="/zh-my/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hans-MY" hreflang="zh-Hans-MY"><span>大马简体</span></a></li><li id="ca-varlang-7" class="ca-variants-zh-Hans-SG mw-list-item"><a href="/zh-sg/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hans-SG" hreflang="zh-Hans-SG"><span>新加坡简体</span></a></li><li id="ca-varlang-8" class="ca-variants-zh-Hant-TW mw-list-item"><a href="/zh-tw/%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92" lang="zh-Hant-TW" hreflang="zh-Hant-TW"><span>臺灣正體</span></a></li> </ul> </div> </div> </div> </div> </nav> 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class="infobox-title summary">人类蛋白质组计划<br />HUMAN PROTEOME PROJECT</caption><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">内容</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E7%94%9F%E7%89%A9" title="生物">有機體</a></th><td class="infobox-data" style="">智人</td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">相關信息</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E7%A0%94%E7%A9%B6%E4%B8%AD%E5%BF%83" class="mw-redirect" title="研究中心">研究中心</a></th><td class="infobox-data" style=""><a href="/wiki/%E4%BA%BA%E9%A1%9E%E8%9B%8B%E7%99%BD%E8%B3%AA%E7%B5%84%E7%B5%84%E7%B9%94" title="人類蛋白質組組織">人类蛋白质组组织</a>(HUPO)</td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E5%AE%9E%E9%AA%8C%E5%AE%A4" title="实验室">实验室</a></th><td class="infobox-data" style="">多个</td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">访问入口</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;">网站</th><td class="infobox-data" style=""><span class="url"><a rel="nofollow" class="external text" href="http://www.thehpp.org/">www<wbr />.thehpp<wbr />.org</a></span><br /><span class="url"><a rel="nofollow" class="external text" href="http://www.c-hpp.org/">www<wbr />.c-hpp<wbr />.org</a></span></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/Web%E6%9C%8D%E5%8A%A1" title="Web服务">網絡服務</a>地址</th><td class="infobox-data" style=""><span class="url"><a rel="nofollow" class="external text" href="http://www.nextprot.org/rest/">NextProt REST</a></span><br /><span class="url"><a rel="nofollow" class="external text" href="http://wiki.thegpm.org/wiki/GPMDB_REST">GPMDB REST</a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">工具</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">其他</th></tr></tbody></table> <p><b>人类蛋白质组计划</b>(<span lang="en">Human proteome project</span>,缩写:HPP)<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup>是由<a href="/wiki/%E4%BA%BA%E9%A1%9E%E8%9B%8B%E7%99%BD%E8%B3%AA%E7%B5%84%E7%B5%84%E7%B9%94" title="人類蛋白質組組織">人类蛋白质组组织</a>(HUPO)<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup>协调的合作计划,目标是通过<a href="/wiki/%E5%AE%9E%E9%AA%8C" title="实验">实验</a>观察所有从<a href="/wiki/%E4%BA%BA%E9%A1%9E%E5%9F%BA%E5%9B%A0%E7%B5%84" title="人類基因組">人类基因组</a><a href="/wiki/%E7%BF%BB%E8%AD%AF_(%E7%94%9F%E7%89%A9%E5%AD%B8)" title="翻譯 (生物學)">翻译</a>序列产生的<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8" title="蛋白质">蛋白质</a>。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="历史"><span id=".E5.8E.86.E5.8F.B2"></span>历史</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=1" title="编辑章节:历史"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>人类蛋白质组组织已成为许多长期运行的蛋白质组学研究项目的协调机构,这些研究项目与临床兴趣的特定人体组织有关,如<a href="/wiki/%E8%A1%80%E6%B5%86" title="血浆">血浆</a><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup>,<a href="/wiki/%E8%82%9D" class="mw-redirect" title="肝">肝</a><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup>,<a href="/wiki/%E8%84%91" title="脑">脑</a><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup>,和<a href="/wiki/%E5%B0%BF" title="尿">尿</a><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup>。它还负责与蛋白质大规模研究相关的具体技术<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup>和标准<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup>。 </p><p>在科学文献中,将平行于<a href="/wiki/%E4%BA%BA%E7%B1%BB%E5%9F%BA%E5%9B%A0%E7%BB%84%E8%AE%A1%E5%88%92" title="人类基因组计划">人类基因组计划</a>的一个更大项目的结构和目标被辩论<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">&#91;</span>10<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">&#91;</span>12<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup>。经过2009年、2010年和2011年世界大会和一系列会议,人类蛋白质组组织将人类蛋白质组计划分为两个子项目C-HPP和B/D-HPP进行<sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup>。其中C-HPP将分成25工作组,每个<a href="/wiki/%E4%BA%BA%E9%A1%9E%E6%9F%93%E8%89%B2%E9%AB%94" class="mw-redirect" title="人類染色體">人类染色体</a>1个工作组。而B/D-HPP将按照蛋白质的生物学和疾病相关性进行分组<sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="项目和工作组"><span id=".E9.A1.B9.E7.9B.AE.E5.92.8C.E5.B7.A5.E4.BD.9C.E7.BB.84"></span>项目和工作组</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=2" title="编辑章节:项目和工作组"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>当前设定的工作组列举如下(取自<a rel="nofollow" class="external text" href="http://www.c-hpp.org/">www.c-hpp.org</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20200526041041/http://www.c-hpp.org/">页面存档备份</a>,存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>)),按照<a href="/wiki/%E6%9F%93%E8%89%B2%E4%BD%93" title="染色体">染色体</a>顺序排序。 </p> <table class="wikitable"> <tbody><tr> <th align="center">染色体 </th> <th align="center">组长 </th> <th align="center">所属机构国家或地区 </th></tr> <tr> <td align="center">1 </td> <td align="center">Fuchu He </td> <td align="center">中国 </td></tr> <tr> <td align="center">2 </td> <td align="center">Lydie Lane </td> <td align="center">瑞士 </td></tr> <tr> <td align="center">3 </td> <td align="center">Toshihide Nishimura </td> <td align="center">日本 </td></tr> <tr> <td align="center">4 </td> <td align="center">Yu Ju Chen </td> <td align="center">台湾 </td></tr> <tr> <td align="center">5 </td> <td align="center">Rainer Bischoff </td> <td align="center">荷兰 </td></tr> <tr> <td align="center">6 </td> <td align="center">Paul Keown </td> <td align="center">加拿大 </td></tr> <tr> <td align="center">7 </td> <td align="center">Mark Baker </td> <td align="center">澳大利亚、新西兰 </td></tr> <tr> <td align="center">8 </td> <td align="center">Pengyuan Yang </td> <td align="center">中国 </td></tr> <tr> <td align="center">9 </td> <td align="center">Je-Yoel Cho </td> <td align="center">韩国,汉城 </td></tr> <tr> <td align="center">10 </td> <td align="center">Joshua Labaer </td> <td align="center">美国 </td></tr> <tr> <td align="center">11 </td> <td align="center">Jong Shin Yoo </td> <td align="center">韩国 </td></tr> <tr> <td align="center">12 </td> <td align="center">Visith Thongboonkerd </td> <td align="center">印度、新加坡、台湾、泰国 </td></tr> <tr> <td align="center">13 </td> <td align="center">Young Ki Paik </td> <td align="center">韩国 </td></tr> <tr> <td align="center">14 </td> <td align="center">Jérôme Garin </td> <td align="center">法国 </td></tr> <tr> <td align="center">15 </td> <td align="center">Gilberto B Domont </td> <td align="center">巴西 </td></tr> <tr> <td align="center">16 </td> <td align="center">Fernando Corrales </td> <td align="center">西班牙 </td></tr> <tr> <td align="center">17 </td> <td align="center">Bill Hancock </td> <td align="center">美国 </td></tr> <tr> <td align="center">18 </td> <td align="center">Alex Archakov </td> <td align="center">俄国 </td></tr> <tr> <td align="center">19 </td> <td align="center">Gyorgy Marko Varga </td> <td align="center">瑞典 </td></tr> <tr> <td align="center">20 </td> <td align="center">Siqiu Liu </td> <td align="center">中国 </td></tr> <tr> <td align="center">21 </td> <td align="center">Daniel Figeys </td> <td align="center">加拿大 </td></tr> <tr> <td align="center">22 </td> <td align="center">Charles Lee </td> <td align="center">美国 </td></tr> <tr> <td align="center">X </td> <td align="center">Tadashi Yamamoto </td> <td align="center">日本 </td></tr> <tr> <td align="center">Y </td> <td align="center">Hosseini Salekdeh </td> <td align="center">伊朗 </td></tr> <tr> <td align="center">MT </td> <td align="center">Andrea Urbani </td> <td align="center">意大利 </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="计算资源"><span id=".E8.AE.A1.E7.AE.97.E8.B5.84.E6.BA.90"></span>计算资源</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=3" title="编辑章节:计算资源"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>由Eric Deutsch领导的、美国西雅图系统生物研究所(<span class="ilh-all" data-orig-title="PeptideAtlas" data-lang-code="en" data-lang-name="英语" data-foreign-title="PeptideAtlas"><span class="ilh-page"><a href="/w/index.php?title=PeptideAtlas&amp;action=edit&amp;redlink=1" class="new" title="PeptideAtlas(页面不存在)">PeptideAtlas</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/PeptideAtlas" class="extiw" title="en:PeptideAtlas"><span lang="en" dir="auto">PeptideAtlas</span></a></span>)</span></span>)的小组正在提供基于MS/MS的蛋白质组学结果的数据简化、分析和验证。与<a href="/wiki/%E6%8A%97%E4%BD%93" title="抗体">抗体</a>方法相关的数据处理由在瑞典斯德哥尔摩的Kalle von Feilitzen(Human Protein Atlas)进行协调。在瑞士日内瓦SIB的Lydie Lane负责整体整合和报告信息(<span class="ilh-all" data-orig-title="NeXtProt" data-lang-code="en" data-lang-name="英语" data-foreign-title="NeXtProt"><span class="ilh-page"><a href="/w/index.php?title=NeXtProt&amp;action=edit&amp;redlink=1" class="new" title="NeXtProt(页面不存在)">NeXtProt</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/NeXtProt" class="extiw" title="en:NeXtProt"><span lang="en" dir="auto">NeXtProt</span></a></span>)</span></span>)。生成的所有数据都存入<span class="ilh-all" data-orig-title="ProteomeXchange" data-lang-code="en" data-lang-name="英语" data-foreign-title="ProteomeXchange"><span class="ilh-page"><a href="/w/index.php?title=ProteomeXchange&amp;action=edit&amp;redlink=1" class="new" title="ProteomeXchange(页面不存在)">ProteomeXchange</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/ProteomeXchange" class="extiw" title="en:ProteomeXchange"><span lang="en" dir="auto">ProteomeXchange</span></a></span>)</span></span>数据库,作为HPP贡献的一部分。 </p> <div class="mw-heading mw-heading2"><h2 id="现状"><span id=".E7.8E.B0.E7.8A.B6"></span>现状</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=4" title="编辑章节:现状"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>正在进行的按照染色体为基础的人类蛋白质组计划是《蛋白质组研究杂志》(Journal of Proteome Research)特刊(2014年1月3日,第13卷,第1期)的主题。整个项目的状态是在该期上的社论讨论<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup>。 </p><p>一个单独的<a rel="nofollow" class="external text" href="http://c-hpp.webhosting.rug.nl/tiki-index.php?page=HomePage">CHPP-维基</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20201031044814/http://c-hpp.webhosting.rug.nl/tiki-index.php?page=HomePage">页面存档备份</a>,存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>)已经被该项目的生物信息学组建立维护当前项目的信息,包括会议、活动、标准操作程序和其他特殊资源的个体染色体团队。 </p><p>与蛋白质观察相关的置信水平的指标是本项目的关键组成部分。如何定义对所使用的各种实验协议有意义的指标是正在进行的辩论的主题:目前的共识度量已经被发布<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup>。 </p><p>描述项目最新状况的杂志文章,并宣布推出“Missing ProteinPedia”可以在这里被发现<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="参阅"><span id=".E5.8F.82.E9.98.85"></span>参阅</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=5" title="编辑章节:参阅"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84" title="蛋白质组">蛋白质组</a></li> <li><a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E5%AD%A6" title="蛋白质组学">蛋白质组学</a></li> <li><span class="ilh-all" data-orig-title="BioPlex" data-lang-code="en" data-lang-name="英语" data-foreign-title="BioPlex"><span class="ilh-page"><a href="/w/index.php?title=BioPlex&amp;action=edit&amp;redlink=1" class="new" title="BioPlex(页面不存在)">BioPlex</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/BioPlex" class="extiw" title="en:BioPlex"><span lang="en" dir="auto">BioPlex</span></a></span>)</span></span></li></ul> <div class="mw-heading mw-heading2"><h2 id="参考资料"><span id=".E5.8F.82.E8.80.83.E8.B5.84.E6.96.99"></span>参考资料</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=6" title="编辑章节:参考资料"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text">Legrain, P. et al. The human proteome project: Current state and future direction. Mol Cell Proteomics. 10:M111.009993 (2011).</span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text">HUPO (Human Proteome Organization) 1st World Congress. Mol Cell Proteomics. 9:651-752 (2002).</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text">Omenn, G.S. et al. Overview of the HUPO Plasma Proteome Project. <i>Proteomics</i>. 5, 3226-45 (2005).</span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text">He, F. Human liver proteome project: plan, progress, and perspectives. Mol Cell Proteomics. 4, 1841-8 (2005).</span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text">Hamacher, M. et al. HUPO Brain Proteome Project: toward a code of conduct. Mol Cell Proteomics. 7, 457 (2008).</span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text">Yamamoto, T., Langham, R.G., Ronco, P., Knepper, M.A. &amp; Thongboonkerd, V. Towards standard protocols and guidelines for urine proteomics. <i>Proteomics</i>. 8, 2156-9 (2008).</span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text">Uhlen, M. &amp; Ponten, F. Antibody-based proteomics for human tissue profiling. Mol Cell Proteomics. 4, 384-93 (2005).</span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text">Orchard, S. et al. Current status of proteomic standards development. Expert Rev Proteomics. 1, 179-83 (2005).</span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text">Archakov A, et al. The Moscow HUPO Human Proteome Project workshop. Mol Cell Proteomics. 8:2199-200 (2009).</span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text">Baker MS. Building the 'practical' human proteome project - the next big thing in basic and clinical proteomics. Curr Opin Mol Ther. 2009 11:600-2 (2009).</span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-11">^</a></b></span> <span class="reference-text">Editorial, The call of the human proteome. Nat Methods. 7:661 (2010).</span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text">Rabilloud T., et al. Is a gene-centric human proteome project the best way for proteomics to serve biology? <i>Proteomics</i>. 10:3067-72 (2010).</span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-13">^</a></b></span> <span class="reference-text">Editorial. A Gene-centric Human Proteome Project. Mol Cell Proteomics. 9:427-429 (2010).</span> </li> <li id="cite_note-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-14">^</a></b></span> <span class="reference-text">Paik, Y-K., et al. A Chromosome-Centric Human Proteome Project to Characterize the Sets of Proteins Encoded in the Genome. Nature Biotech.30: 221–3(2012).</span> </li> <li id="cite_note-15"><span class="mw-cite-backlink"><b><a href="#cite_ref-15">^</a></b></span> <span class="reference-text">Aebersold R., et al. The Biology/Disease-driven Human Proteome Project (B/D-HPP): Enabling Protein Research for the Life Sciences Community. <i>J. Proteome Res</i>. 12:23–27 (2013).</span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text">Paik Y-K., et al. Genome-wide Proteomics, Chromosome-centric Human Proteome Project (C-HPP), Part II. <i>J. Proteome Res</i>. 13:1–4 (2014).</span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-17">^</a></b></span> <span class="reference-text">Omenn GS., et al. Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification. J Proteome Res. 14:3452-60 (2015).</span> </li> <li id="cite_note-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-18">^</a></b></span> <span class="reference-text">Horvatovich P., et al. A Quest for Missing Proteins: update 2015 on Chromosome-Centric Human Proteome Project. J Proteome Res. Jun 15 (2015).</span> </li> <li id="cite_note-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-19">^</a></b></span> <span class="reference-text"><cite class="citation journal">Baker, MS; et al. Accelerating the search for the missing proteins in the human proteome. Nature Communications. 2017, <b>8</b>. <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fncomms14271"><span title="數位物件識別號">doi:10.1038/ncomms14271</span></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;rft.atitle=Accelerating+the+search+for+the+missing+proteins+in+the+human+proteome&amp;rft.aufirst=MS&amp;rft.aulast=Baker&amp;rft.date=2017&amp;rft.genre=article&amp;rft.jtitle=Nature+Communications&amp;rft.volume=8&amp;rft_id=info%3Adoi%2F10.1038%2Fncomms14271&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span><span class="citation-comment" style="display:none; color:#33aa33"> 引文格式1维护:显式使用等标签 (<a href="/wiki/Category:%E5%BC%95%E6%96%87%E6%A0%BC%E5%BC%8F1%E7%BB%B4%E6%8A%A4%EF%BC%9A%E6%98%BE%E5%BC%8F%E4%BD%BF%E7%94%A8%E7%AD%89%E6%A0%87%E7%AD%BE" title="Category:引文格式1维护:显式使用等标签">link</a>)</span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="外部链接"><span id=".E5.A4.96.E9.83.A8.E9.93.BE.E6.8E.A5"></span>外部链接</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E4%BA%BA%E7%B1%BB%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E8%AE%A1%E5%88%92&amp;action=edit&amp;section=7" title="编辑章节:外部链接"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ol><li><span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="英語">(英文)</span><a rel="nofollow" class="external text" href="https://hupo.org/human-proteome-project/">HPP project page (www.hupo.org)</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20210207150221/https://hupo.org/human-proteome-project/">页面存档备份</a>,存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>)</li> <li><span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="英語">(英文)</span><a rel="nofollow" class="external text" href="http://www.thehpp.org/">HPP web site (www.thehpp.org)</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20170720131734/http://www.thehpp.org/">页面存档备份</a>,存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>)</li> <li><span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="英語">(英文)</span><a rel="nofollow" class="external text" href="http://www.c-hpp.org/">Chromosome-centric HPP web site (www.c-hpp.org)</a> (<a rel="nofollow" class="external text" href="//web.archive.org/web/20200526041041/http://www.c-hpp.org/">页面存档备份</a>,存于<a 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href="https://en.wikipedia.org/wiki/Cognitive_genomics" class="extiw" title="en:Cognitive genomics"><span lang="en" dir="auto">Cognitive genomics</span></a></span>)</span></span></li> <li><span class="ilh-all" data-orig-title="计算基因组学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Computational genomics"><span class="ilh-page"><a href="/w/index.php?title=%E8%AE%A1%E7%AE%97%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="计算基因组学(页面不存在)">计算基因组学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Computational_genomics" class="extiw" title="en:Computational genomics"><span lang="en" dir="auto">Computational genomics</span></a></span>)</span></span></li> <li><a href="/wiki/%E6%AF%94%E8%BE%83%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6" title="比较基因组学">比较基因组学</a></li> <li><a href="/wiki/%E5%9F%BA%E5%9B%A0%E7%BB%84%E8%AE%A1%E5%88%92" title="基因组计划">基因组计划</a> <ul><li><a href="/wiki/%E4%BA%BA%E7%B1%BB%E5%9F%BA%E5%9B%A0%E7%BB%84%E8%AE%A1%E5%88%92" title="人类基因组计划">人类基因组计划</a></li></ul></li> <li><span class="ilh-all" data-orig-title="古多倍性" data-lang-code="en" data-lang-name="英语" data-foreign-title="Paleopolyploidy"><span class="ilh-page"><a href="/w/index.php?title=%E5%8F%A4%E5%A4%9A%E5%80%8D%E6%80%A7&amp;action=edit&amp;redlink=1" class="new" title="古多倍性(页面不存在)">古多倍性</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Paleopolyploidy" class="extiw" title="en:Paleopolyploidy"><span lang="en" dir="auto">Paleopolyploidy</span></a></span>)</span></span></li> <li><a href="/wiki/%E5%AE%8F%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6" title="宏基因组学">宏基因组学</a> <ul><li><a href="/wiki/%E4%BA%BA%E7%B1%BB%E5%BE%AE%E7%94%9F%E7%89%A9%E7%BB%84%E8%AE%A1%E5%88%92" title="人类微生物组计划">人类微生物组计划</a></li></ul></li> <li><span class="ilh-all" data-orig-title="功能基因组学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Functional genomics"><span class="ilh-page"><a href="/w/index.php?title=%E5%8A%9F%E8%83%BD%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="功能基因组学(页面不存在)">功能基因组学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Functional_genomics" class="extiw" title="en:Functional genomics"><span lang="en" dir="auto">Functional genomics</span></a></span>)</span></span></li> <li><a href="/wiki/%E6%B3%9B%E5%9F%BA%E5%9B%A0%E7%BB%84" title="泛基因组">泛基因组学</a></li> <li><a href="/wiki/%E4%B8%AA%E4%BA%BA%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6" title="个人基因组学">个人基因组学</a></li> <li><span class="ilh-all" data-orig-title="社会基因组学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Social genomics"><span class="ilh-page"><a href="/w/index.php?title=%E7%A4%BE%E4%BC%9A%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="社会基因组学(页面不存在)">社会基因组学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Social_genomics" class="extiw" title="en:Social genomics"><span lang="en" dir="auto">Social genomics</span></a></span>)</span></span></li> <li><a href="/wiki/%E7%BB%93%E6%9E%84%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6" title="结构基因组学">结构基因组学</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%9F%E7%89%A9%E4%BF%A1%E6%81%AF%E5%AD%A6" title="生物信息学">生物信息学</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E7%94%9F%E7%89%A9%E6%99%B6%E7%89%87" title="生物晶片">生物芯片</a></li> <li><a href="/wiki/%E5%8C%96%E5%AD%A6%E4%BF%A1%E6%81%AF%E5%AD%A6" title="化学信息学">化学信息学</a></li> <li><span class="ilh-all" data-orig-title="化学基因组学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Chemogenomics"><span class="ilh-page"><a href="/w/index.php?title=%E5%8C%96%E5%AD%A6%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="化学基因组学(页面不存在)">化学基因组学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Chemogenomics" class="extiw" title="en:Chemogenomics"><span lang="en" dir="auto">Chemogenomics</span></a></span>)</span></span></li> <li><a href="/wiki/%E5%85%8D%E7%96%AB%E7%BB%84%E5%AD%A6" title="免疫组学">免疫组学</a></li> <li><a href="/wiki/%E8%BF%9E%E6%8E%A5%E7%BB%84%E5%AD%A6" title="连接组学">连接组学</a> <ul><li><span class="ilh-all" data-orig-title="人类连接组计划" data-lang-code="en" data-lang-name="英语" data-foreign-title="Human Connectome Project"><span class="ilh-page"><a href="/wiki/%E4%BA%BA%E9%A1%9E%E9%80%A3%E6%8E%A5%E7%B5%84%E8%A8%88%E5%8A%83" title="人類連接組計劃">人类连接组计划</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Human_Connectome_Project" class="extiw" title="en:Human Connectome Project"><span lang="en" dir="auto">Human Connectome Project</span></a></span>)</span></span></li></ul></li> <li><a href="/wiki/%E8%A1%A8%E8%A7%80%E9%81%BA%E5%82%B3%E5%AD%B8" title="表觀遺傳學">表觀遺傳學</a> <ul><li><a href="/wiki/%E4%BA%BA%E7%B1%BB%E5%A4%96%E5%9F%BA%E5%9B%A0%E7%BB%84%E8%AE%A1%E5%88%92" title="人类外基因组计划">人类外基因组计划</a></li></ul></li> <li><a href="/wiki/%E7%B3%96%E7%BB%84%E5%AD%A6" title="糖组学">糖组学</a></li> <li><a href="/wiki/%E8%84%82%E7%B1%BB%E7%BB%84%E5%AD%A6" title="脂类组学">脂类组学</a></li> <li><a href="/wiki/%E4%BB%A3%E8%B0%A2%E7%89%A9%E7%BB%84%E5%AD%A6" title="代谢物组学">代谢物组学</a></li> <li><span class="ilh-all" data-orig-title="多肽組學" data-lang-code="en" data-lang-name="英语" data-foreign-title="Peptidomics"><span class="ilh-page"><a href="/w/index.php?title=%E5%A4%9A%E8%82%BD%E7%B5%84%E5%AD%B8&amp;action=edit&amp;redlink=1" class="new" title="多肽組學(页面不存在)">多肽組學</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Peptidomics" class="extiw" title="en:Peptidomics"><span lang="en" dir="auto">Peptidomics</span></a></span>)</span></span></li> <li><span class="ilh-all" data-orig-title="药物遗传学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Pharmacogenetics"><span class="ilh-page"><a href="/w/index.php?title=%E8%8D%AF%E7%89%A9%E9%81%97%E4%BC%A0%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="药物遗传学(页面不存在)">药物遗传学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Pharmacogenetics" class="extiw" title="en:Pharmacogenetics"><span lang="en" dir="auto">Pharmacogenetics</span></a></span>)</span></span></li> <li><a href="/wiki/%E8%8D%AF%E7%89%A9%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6" title="药物基因组学">药物基因组学</a></li></ul> <ul><li><span class="ilh-all" data-orig-title="影像组学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Radiomics"><span class="ilh-page"><a href="/w/index.php?title=%E5%BD%B1%E5%83%8F%E7%BB%84%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="影像组学(页面不存在)">影像组学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Radiomics" class="extiw" title="en:Radiomics"><span lang="en" dir="auto">Radiomics</span></a></span>)</span></span></li> <li><a href="/wiki/%E7%B3%BB%E7%BB%9F%E7%94%9F%E7%89%A9%E5%AD%A6" title="系统生物学">系统生物学</a></li> <li><span class="ilh-all" data-orig-title="毒理基因组学" data-lang-code="en" data-lang-name="英语" data-foreign-title="Toxicogenomics"><span class="ilh-page"><a href="/w/index.php?title=%E6%AF%92%E7%90%86%E5%9F%BA%E5%9B%A0%E7%BB%84%E5%AD%A6&amp;action=edit&amp;redlink=1" class="new" title="毒理基因组学(页面不存在)">毒理基因组学</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Toxicogenomics" class="extiw" title="en:Toxicogenomics"><span lang="en" dir="auto">Toxicogenomics</span></a></span>)</span></span></li> <li><a href="/wiki/%E8%BD%AC%E5%BD%95%E7%BB%84" title="转录组">转录物组学</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%BB%93%E6%9E%84%E7%94%9F%E7%89%A9%E5%AD%A6" title="结构生物学">结构生物学</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8%E7%BB%84%E5%AD%A6" title="蛋白质组学">蛋白质组学</a> <ul><li><a class="mw-selflink selflink">人类蛋白质组计划</a></li></ul></li> <li><a href="/wiki/%E8%8D%AF%E7%89%A9%E8%AE%BE%E8%AE%A1" class="mw-redirect" title="药物设计">结构药物设计</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">研究工具</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E5%8F%8C%E5%90%91%E7%94%B5%E6%B3%B3" title="双向电泳">双向电泳</a></li> <li><a href="/wiki/%E8%B4%A8%E8%B0%B1%E6%B3%95" title="质谱法">质谱法</a></li> <li><span class="ilh-all" data-orig-title="电喷雾离子法" data-lang-code="en" data-lang-name="英语" data-foreign-title="Electrospray ionization"><span class="ilh-page"><a href="/w/index.php?title=%E7%94%B5%E5%96%B7%E9%9B%BE%E7%A6%BB%E5%AD%90%E6%B3%95&amp;action=edit&amp;redlink=1" class="new" title="电喷雾离子法(页面不存在)">电喷雾离子法</a></span><span class="noprint ilh-comment">(<span class="ilh-lang">英语</span><span class="ilh-colon">:</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Electrospray_ionization" class="extiw" title="en:Electrospray ionization"><span lang="en" dir="auto">Electrospray ionization</span></a></span>)</span></span>(ESI)</li> <li><a href="/wiki/%E5%9F%BA%E8%B4%A8%E8%BE%85%E5%8A%A9%E6%BF%80%E5%85%89%E8%A7%A3%E5%90%B8/%E7%94%B5%E7%A6%BB" title="基质辅助激光解吸/电离">基质辅助激光解吸/电离</a>(MALDI)</li> <li><a href="/wiki/%E5%BE%AE%E6%B5%81%E6%8E%A7" title="微流控">微流控</a></li> <li><a href="/wiki/%E5%90%8C%E4%BD%8D%E7%B4%A0%E6%A0%87%E8%AE%B0" title="同位素标记">同位素标记</a></li> <li><a href="/wiki/%E6%9F%93%E8%89%B2%E4%BD%93%E6%9E%84%E8%B1%A1%E6%8D%95%E8%8E%B7" title="染色体构象捕获">染色体构象捕获</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">机构</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E5%9B%BD%E7%AB%8B%E5%8D%AB%E7%94%9F%E7%A0%94%E7%A9%B6%E9%99%A2_(%E7%BE%8E%E5%9B%BD)" class="mw-redirect" title="国立卫生研究院 (美国)">国立卫生研究院 (美国)</a></li> <li><a href="/wiki/%E6%97%A5%E6%9C%ACDNA%E6%95%B0%E6%8D%AE%E5%BA%93" title="日本DNA数据库">日本DNA数据库</a>(日本)</li> <li><a href="/wiki/%E6%AC%A7%E6%B4%B2%E5%88%86%E5%AD%90%E7%94%9F%E7%89%A9%E5%AD%A6%E5%AE%9E%E9%AA%8C%E5%AE%A4" title="欧洲分子生物学实验室">欧洲分子生物学实验室</a>(欧盟)</li> <li><a href="/wiki/%E7%BB%B4%E5%BA%B7%E6%A1%91%E6%A0%BC%E7%A0%94%E7%A9%B6%E6%89%80" title="维康桑格研究所">维康桑格研究所</a>(英国)</li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><span typeof="mw:File"><span title="分类"><img alt="分类" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, 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