Indena | Quality System

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role="button"> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> <span class="label">Back</span> </a> <div class="left-zone"> <h2>Innovation</h2> <p>Discover the Indena’s way to Innovation</p> <a class="simple-cta menu-cta " data-parent="Innovation" href="https://www.indena.com/us/innovation/"> <span class="label">Go to section</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </div> <div class="links-row"> <div class="links-col"> <ul class="submenu"> <li> <a class="menu-button " data-parent="Innovation" href="https://www.indena.com/us/innovation/rd/" > <span>Research & Development</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button current" data-parent="Innovation" 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Search for them.</p> <a class="simple-cta menu-cta " data-parent="Products" href="https://www.indena.com/us/products/"> <span class="label">Go to section</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </div> <div class="links-row"> <div class="links-col"> <ul class="submenu"> <li> <a class="menu-button " data-parent="Products" href="https://www.indena.com/us/products/pharmaceuticals/" > <span>Pharmaceuticals</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button " data-parent="Products" href="https://www.indena.com/us/products/nutraceuticals/" > <span>Nutraceuticals</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button children " data-parent="Products" href="https://www.indena.com/us/products/phytosome/" > <span>Phytosome<sup>®</sup> Technology</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> </ul> </div> </div> </div> </div> </div> <div class="wd-megamenu" id="item-4262"> <div class="megamenu-overlay"> <div class="megamenu-content center-grid no-h-padding "> <a class="back-menu d-lg-none" role="button"> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> <span class="label">Back</span> </a> <div class="left-zone"> <h2>CDMO Service</h2> <p></p> <a class="simple-cta menu-cta " data-parent="CDMO" href="https://www.indena.com/us/cdmo/"> <span class="label">Go to section</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </div> <div class="links-row"> <div class="links-col"> <ul class="submenu"> </ul> </div> </div> </div> </div> </div> <div class="wd-megamenu" id="item-9265"> <div class="megamenu-overlay"> <div class="megamenu-content center-grid no-h-padding "> <a class="back-menu d-lg-none" role="button"> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> <span class="label">Back</span> </a> <div class="left-zone"> <h2>Things to watch</h2> <p></p> <a class="simple-cta menu-cta " data-parent="Things to watch" href="https://www.indena.com/us/things-to-watch/"> <span class="label">Go to section</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </div> <div class="links-row"> <div class="links-col"> <ul class="submenu"> </ul> </div> </div> </div> </div> </div> <div class="wd-megamenu" id="item-4263"> <div class="megamenu-overlay"> <div class="megamenu-content center-grid no-h-padding half-bottom"> <a class="back-menu d-lg-none" role="button"> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> <span class="label">Back</span> </a> <div class="left-zone"> <h2>Media and news</h2> <p>Here is the right place where you can read all the latest news and information about Indena’s world.</p> </div> <div class="links-row"> <div class="links-col col-25"> <ul class="submenu"> <li> <a class="menu-button " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/news/"> <span>News</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/press-releases/"> <span>Press Releases</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/ad-campaigns/"> <span>AD Campaigns</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/presskit/"> <span>Presskit</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> </ul> </div> <div class="right-zone col-25"> <h2>Events</h2> <p>Take a look on Indena’s Calendar. You will always be aware of our upcoming events.</p> </div> <div class="links-col col-25"> <ul class="submenu"> <li> <a class="menu-button " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/events-calendar/"> <span>Events Calendar</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> <li> <a class="menu-button " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/events-advisory-board/"> <span>Advisory Board</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </li> </ul> </div> </div> </div> </div> <div class="mega-footer"> <div class="megafooter-content center-grid no-h-padding"> <div class="left"> <h2>Indena’s Filestore</h2> </div> <div class="text"> <p>Browse all Indena’s documents about products, events, company information and so much more.</p> <a class="simple-cta menu-cta " data-parent="Media and Events" href="https://www.indena.com/us/media-and-events/indenas-filestore/"> <span class="label">Go to section</span> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </a> </div> </div> </div> </div> </header> <main id="main"> <div class="color-change-wrapper">  <section class="hero-page positive white" data-bg="white"> <div class="hero-page-wrapper"> <div class="hero-page-viewport hero-variation hero-page-gradient"> <div class="img-wrapper"> <div class="padding-ratio"> <picture class="img-fill"> <source srcset="https://www.indena.com/indena_files/2020/12/quality-hero-lg-1.jpg" media="(min-width: 992px)"> <source srcset="https://www.indena.com/indena_files/2021/02/quality-hero-sm-2.jpg" media="(min-width: 320px)"> <img class="fill" src="https://www.indena.com/indena_files/2020/12/quality-hero-lg-1.jpg" alt="QUALITY"> </picture> </div> </div> <div class="hero-page-text"> <div class="hero-page-title "> <nav class="breadcrumbs"> <ul class="page-tree"><li><a href="https://www.indena.com/us/">Home</a></li> <li>Innovation</li> <li>Quality</li></ul> </nav> <p class="category">QUALITY</p> <h1 class="">Quality Never Stops</h1> </div> <div class="hero-page-content"> <p class="text-big">Quality Never Stops</p> </div> <div class="hero-page-scroll"> <p> <svg class="icon sm"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> <span class="label">Scroll to see more</span> </p> </div> </div> </div> <div class="hero-page-search-share"> <form class="free-search " method="get" action="https://www.indena.com/us/innovation/quality/" id="freeSearchForm"> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-search"></use></svg> <input id="free_search" type="text" name="s" placeholder="Search" value=""> <button type="submit"> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-arrow-r"></use></svg> </button> </form> </div> </div> </section> <section id="part_0" class="complete-text-block offset-left offset-right white " data-bg="white" > <div class="complete-text-block-wrapper"> <div class="br-wrapper" data-aos="fade-up" data-aos-duration="1000"> <nav class="breadcrumbs"><ul class="page-tree"><li><a href="https://www.indena.com/us/">Home</a></li> <li>Innovation</li> <li>Quality</li></ul></nav> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000"> <div class="text-row"> <div class="left"> <h2><strong>We believe that quality must be for everyone</strong></h2> </div> <div class="right"> <p><b>With our exciting and engaging work, we want to bring the widest possible awareness about this paramount value to the world of phytochemistry.<br></b>For us, quality is not a special side project. It is an inclination, a daily practice, a constant, an unavoidable requirement for products, processes, technologies, services and solutions. We always strive to dissect, analyze and constantly evolve our quality system, ensuring even more fairness in the system itself.<br></p> </div> </div> </div> </div> </section> <div id="part_1" class="h2-anchor-wrapper small-padding-bottom-desk offset-left offset-right" data-bg="white"> <h2 class="js-anchor" id="section_1">Quality</h2> </div> <section id="part_2" class="complete-text-block padding-bottom offset-left offset-right white bg-grid " data-bg="white" > <div class="complete-text-block-wrapper"> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000"> <p class="pre-title">Our approach</p> <div class="text-row"> <div class="left"> <h2><strong>21st -Century Quality Management</strong></h2> </div> <div class="right"> <p>Quality gurus predicted this will be remembered as the century of quality.<br>At Indena, we have always placed quality at the very core of our business, tackling the complexities it presents for natural substances, active ingredients and extracts to always operate at the best level possible, based on our knowledge.<br><b>To us, quality is not simply the brilliant implementation of a standard applied to individual parts and components, but a comprehensive design approach to business as a whole.</b><br><a>Because today, one of the basic principles in quality management states quality cannot be merely tested in the final result, but should be built into products since the very beginning of manufacturing process.</a><br></p> </div> </div> </div> </div> </section> <section id="part_3" class="text-image-block padding-bottom offset-left offset-right grey " data-bg="grey" > <div class="text-image-block-wrapper"> <div class="text negative"> <div class="text-content" data-aos="fade-up" data-aos-duration="1000"> <div class="pre-title">Our mindset</div> <h3>Quality Pathway Unlocked</h3> <p><b>How do we define quality?</b><br /> The term “quality” is more complicated than it may appear: literature shows even experts give a wide range of somewhat different definitions for it.<br /> One way to describe quality is “customer satisfaction" or "meeting customer expectations” - but this usually refers to final users who are often not able to independently assess the quality of the products they use.<br /> A more solid and modern definition of quality is <i>“fitness for intended use”</i> or <i>“fitness for purpose”</i>.<br /> In other words, a high-quality product is expected to deliver the benefits and performance at the levels conveyed by its label claims, and to continue to do so throughout its lifetime. This is the definition that guides our quality system, and inspires us at every step of the production process, from R&D to packaging.<br /> </b><br /> </p> </div> </div> <div class="image"> <div class="image-wrapper"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/quality-management-and-the-21st-century-lg.jpg" alt="Quality Pathway Unlocked"> <div class="img-loader"></div> </div> </div> </div> </section> <section id="part_4" class="img-responsive-section offset-left offset-right grey" data-bg="grey" > <div class="img-responsive-section-wrapper"> <div class="img-wrapper"> <div class="padding-ratio "> <picture class="img-fill"> <img class="lazy fill" data-src="https://www.indena.com/indena_files/2020/12/quality-you-can-count-on-lg.jpg" alt="quality-you-can-count-on-lg"> <div class="img-loader"></div> </picture> </div> </div> </div> </section> <section id="part_5" class="complete-text-block offset-left offset-right grey " data-bg="grey" > <div class="complete-text-block-wrapper"> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000"> <p class="pre-title">Indena's Expertise</p> <div class="text-row"> <div class="left"> <h2><strong>Quality You Can Count On</strong></h2> </div> <div class="right"> <p>As a leading manufacturer of active Ingredients, mainly of botanical origin, Indena plays a key role in the production and control of many products for different global markets including pharmaceuticals, nutraceuticals, medical devices and excipients.</p><p>We guarantee customers outstanding quality throughout the development and manufacturing of all of our active ingredients: <strong><br>- APIs for pharmaceutical use <br>- Ingredients for medical devices <br>- Nutraceuticals <br>- Cosmetic ingredients <br>- Excipients for pharmaceutical or other use</strong></p><p>Depending on the manufacturing process, our active ingredients belong to the following categories:<br><strong>- Purified isolated products from vegetable origin</strong><br><strong>- Synthetic products</strong><br><strong>- Semi-synthetic products (where an isolated product of vegetable origin undergoes a subsequent synthetic transformation)<br><strong>- Herbal extracts / Botanical extracts (Pharmaceuticals/ Nutraceuticals)</strong> </strong></p><p><strong>Indena is fully committed to compliance with all current laws and relevant regulations and guidelines, to assure the adequate quality of the products it delivers to customers.</strong></p><p></p> </div> </div> </div> </div> </section> <div id="part_6" class="h2-anchor-wrapper padding-bottom offset-left offset-right" data-bg="grey"> <h2 class="js-anchor" id="section_6">The Active Pharmaceutical Ingredients</h2> </div> <section id="part_7" class="text-image-block padding-bottom grey specular " data-bg="grey" > <div class="text-image-block-wrapper"> <div class="text positive"> <div class="text-content" data-aos="fade-up" data-aos-duration="1000"> <h3>Active Pharmaceutical Ingredients (APIs)</h3> <p>On top of Italian (AIFA) and European regulations, Indena complies with all International Harmonized Pharmaceutical Guidelines (ICH) and follows the relevant harmonized cGMP recommendations.<br /> <br /> In addition, Indena is routinely inspected by all the main worldwide authorities and makes GMP Certificates available to customers. <br /> As regards APIs from vegetable origin in particular, quality controls are carried out starting from plant cultivation in order to ensure full traceability of the plant material and comply with all limits on potential contaminants. <br /> <br /> For herbal extracts and herbal drug preparations, Indena follows all the indications contained within the EMA’s guidelines, including the EU’s GMP Annex 7, “Guideline for the Manufacture of Herbal Medicines”.</p> </div> </div> <div class="image"> <div class="image-wrapper"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/active-pharmaceutical-ingredients-api-1-lg.jpg" alt="Active Pharmaceutical Ingredients (APIs)"> <div class="img-loader"></div> </div> </div> </div> </section> <section id="part_8" class="card-3-col padding-bottom offset-left offset-right grey" data-bg="grey" > <div class="card-3-col-wrapper"> <div class="card-row"> <div class="card-col"> <div class="card-bg"> <div class="card-bg-wrapper"> <div class="img-zone"> <div class="img-wrapper"> <div class="img-mask"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/label.jpg" alt="NUTRACEUTICALS OF BOTANICAL ORIGIN"> </div> </div> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000" > <h2>NUTRACEUTICALS OF BOTANICAL ORIGIN</h2> <div class="paragraph"> <p>Botanical extracts and isolated substances are some of the main ingredients used in nutraceuticals. As such, they are subject to food legislation, including: regulations based on the US’ Food Safety Modernization Act (FSMA) to contribute to the safety of finished nutraceuticals; specific EU food safety requirements (FSMS), a holistic system of prevention based on a specific Prerequisite Program (PRP), represented by Good Health Practices (GHP) and Good Manufacturing Practices (GMP); and specific procedures based on the Hazard Analysis of Critical Control Points (HACCP).</p> </div> </div> </div> </div> </div> <div class="card-col"> <div class="card-bg"> <div class="card-bg-wrapper"> <div class="img-zone"> <div class="img-wrapper"> <div class="img-mask"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/label.jpg" alt="EXCIPIENTS"> </div> </div> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000" > <h2>EXCIPIENTS</h2> <div class="paragraph"> <p><br>It is mandatory to produce excipients for pharmaceutical use according to cGMPs, based on the specific product class (e.g. botanical extracts, semi-synthetic products, isolated from natural source, etc.) and intended use (e.g. parenteral, oral, etc.).</p> </div> </div> </div> </div> </div> <div class="card-col"> <div class="card-bg"> <div class="card-bg-wrapper"> <div class="img-zone"> <div class="img-wrapper"> <div class="img-mask"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/label.jpg" alt="INGREDIENTS FOR MEDICAL DEVICES"> </div> </div> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000" > <h2>INGREDIENTS FOR MEDICAL DEVICES</h2> <div class="paragraph"> <p>Used for different classes of medical devices, they can perform complex functions to assist in the diagnosis, prevention, monitoring or alleviation of distinct medical conditions. They are classified following specific regulations set up in different countries and, according to a “risk-based” system centered on the vulnerability of the human body, taking into account the potential risks associated with devices. Quality standards as strict as those for pharmaceuticals are established for ingredients used for the preparation of injectables or stent devices (e.g. Paclitaxel), while requirements for oral or topical preparations range from pharmaceutical to excipient standards or food guidelines. Quality level is always agreed upon with customers, who set their own demands in line with the intended use of the ingredient.</p> </div> </div> </div> </div> </div> </div> </div> </section> <section id="part_9" class="data-columns small-padding-bottom-desk offset-left offset-right white" data-bg="white" > <div class="data-columns-wrapper"> <div class="data-columns-content"> <div class="data-column-col"> <div class="h2-anchor-wrapper"> <h2 class="js-anchor" id="section_9">THE 10 DIMENSIONS OF QUALITY</h2> </div> <div class="content" data-aos="fade-up" data-aos-duration="1000"> <h3>Quality result from a combination of different aspects, also known as dimensions. <br>They can be listed as follows:</h3> <p><br></p> </div> </div> <div class="data-column-double"> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">1. COMPLIANCE WITH LAWS AND REGULATIONS</span> <p>This is the main basic requirement to comply with, and it is linked to the national and regional regulations applied where the product is marketed.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">2. LABEL PERFORMANCE</span> <p>A product should be able to satisfy as intended the rational for its use: it must maintain the efficacy or the physiological effect it was designed to have during clinical trials, according to its class. Label performance refers to a product’s primary operating features, and involves measurable attributes – so brands can usually be ranked objectively according to individual aspects of performance.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">3. CONFORMANCE</span> <p>Conformance is the degree to which a product’s design and operating characteristics meet established standards. One of the most common measures of failure in conformance are defect rates.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">4. LACK OF CONTAMINATION</span> <p>Product must be free of toxic contaminants deriving from the manufacturing process, environment or degradants.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">5. RELIABILITY</span> <p>This dimension reflects the probability of a product failing within a specified time period. Among the most common measures of reliability are the mean time to first failure, the mean time between failures, and the failure rate per unit time.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">6. DURABILITY</span> <p>A measure of product life, durability has both economic and technical implications. Technically, it can be defined as the amount of use one gets from a product before it deteriorates.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">7. AVAILABILITY</span> <p>The product should be readily available for use. It is mainly linked to the process capability and production capacity.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">8. FEATURES</span> <p>Features are usually secondary aspects of performance, as characteristics that supplement products’ and services’ basic functioning. The line separating primary performance characteristics from secondary features is often difficult to draw.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">9. SERVICEABILITY</span> <p>Consumers are concerned not only about a product breaking down but also about the time before service is restored, the timeliness with which service appointments are kept, the nature of interactions with service personnel and the frequency with which service calls or repairs fail to correct outstanding problems. When problems are not immediately resolved and complaints are filed, the procedure a company follows in handling the situation is also likely to affect customers’ ultimate evaluation of product and service quality.</p> </div> </div> </div> <div class="content"> <div class="data-column-block"> <div class="text-wrapper" data-aos="fade-up" data-aos-duration="1000"> <span class="num">10. PERCEIVED QUALITY</span> <p>Consumers don’t always have complete information about a product’s or service’s attributes: indirect measures may be their only basis for comparing brands. A product’s durability, for example, can seldom be observed directly and is usually inferred from its various tangible and intangible aspects. In such circumstances, images, advertising, and brand names – inferences about quality, rather than the reality itself – can be critical.</p> </div> </div> </div> </div> </div> </div> </section> <section id="part_10" class="complete-text-block white bg-grid " data-bg="white" > <div class="complete-text-block-wrapper"> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000"> <p class="pre-title">Our mindful innovation</p> <div class="text-row"> <div class="left"> <h2><strong>Tools Toward Total Quality</strong></h2> </div> <div class="right"> <p><b>FROM PRODUCT TESTING TO QUALITY BY DESIGN</b></p><p><b>Indena pursues innovation also in the field of quality, towards a Total Quality Management System aimed at preventing, rather than detecting, defects.</b><br>Although the responsibilities for assuring product quality belong primarily to quality assurance personnel<b>, they encompass many departments and disciplines in all the fields in which Indena is involved - starting from R&D, regulatory, chemistry, agronomy, botanical, manufacturing and statistics teams, up to final quality control and product release for customers.</b><br>Many new analytical tools are currently being developed and validated to improve the quality of the final products during the manufacturing phase and final controls.<br>Examples of innovations in the field of quality control are the use of genomic tools for the quick and secure classification/confirmation of plant species, and the development of biosensors to assess the quick identification of contaminants from environmental, process and botanical sources.</p> </div> </div> </div> </div> </section> <div id="part_11" class="h2-anchor-wrapper padding-top small-padding-bottom-desk offset-left offset-right" data-bg="white"> <h2 class="js-anchor" id="section_11">IN DNA</h2> </div> <section id="part_12" class="text-image-block padding-top padding-bottom offset-left offset-right grey specular " data-bg="grey" > <div class="text-image-block-wrapper"> <div class="text negative"> <div class="text-content" data-aos="fade-up" data-aos-duration="1000"> <div class="pre-title"> Making an even better product</div> <h3>DNA BARCODING </h3> <p>Indena successfully faced a market need for regulation by investing in technology: following a scandal in the supplement industry, the American market decided to develop genomic identification tests for natural products.<br /> This challenge led to an innovative intuition: genomic analysis as an easy tool to directly verify a plant’s authenticity. Today, Indena identifies every plant coming into the company using genomic technology.</p> </div> </div> <div class="image"> <div class="image-wrapper"> <img class="lazy" data-src="https://www.indena.com/indena_files/2021/01/InDna-verifiedPlant_Q.jpg" alt="DNA BARCODING "> <div class="img-loader"></div> </div> </div> </div> </section> <section id="part_13" class="banner-download padding-bottom offset-left offset-right grey" data-bg="grey" > <div class="banner-download-wrapper"> <div class="container-fluid"> <div class="row"> <div class="col-12 col-md-3 image-wrapper"> <img src="https://www.indena.com/indena_files/2021/01/catalogo-generico.png" alt="DNA BARCODING Whitepaper"> </div> <div class="col-12 col-md-9 col-lg-8 content-wrapper"> <div class="content"> <div class="text" data-aos="fade-up" data-aos-duration="1000"> <h2>DNA BARCODING Whitepaper</h2> </div> <div class="cta"> <div class="btn-wrapper" data-aos="fade-up" data-aos-duration="1000"> <div class="wd-button-wrapper"> <a id="open-filebanner-13-1" role="link" class="wd-button primary" href="https://www.indena.com/indena_files/2021/01/DNA_Barcoding.pdf" target="_blank"> <span class="button-label">Download</span> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-download"></use></svg> </a> </div> </div> </div> </div> </div> </div> </div> </div> </section> <section id="part_14" class="card-3-col small-padding-bottom-desk offset-left offset-right grey" data-bg="grey" > <div class="card-3-col-wrapper"> <div class="card-row"> <div class="card-col"> <div class="card-bg"> <div class="card-bg-wrapper"> <div class="img-zone"> <div class="img-wrapper"> <div class="img-mask"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/label.jpg" alt="The potential pitfall "> </div> </div> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000" > <h2>The potential pitfall </h2> <p>BOTANICAL DNA ID</p> <div class="paragraph"> <p>There is no check for origin in the DNA genomic data deposited in public databases (e.g. Genbank): the system lacks “reference” DNA profiles deriving from the analysis of plant samples of known, certified origin such as herbariums and taxonomically identified specimens.Therefore, it is of paramount importance to have certified, pure samples in order to derive reference DNA sequences. Building a solid genomic database is essential for us to produce species-specific methods, which can distinguish one particular plant from another and thus from adulterants.</p> </div> </div> </div> </div> </div> <div class="card-col"> <div class="card-bg"> <div class="card-bg-wrapper"> <div class="img-zone"> <div class="img-wrapper"> <div class="img-mask"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/label.jpg" alt="The six points of proof "> </div> </div> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000" > <h2>The six points of proof </h2> <p>INDENA’S APPROACH TO GENOMIC IDENTIFICATION</p> <div class="paragraph"> <p>DNA barcoding is <b>orthogonal</b>: a single technique may not be enough. <b> A strong botanical background</b> to structure DNA methodologies. <b>Leverage the ability to use the whole range of available DNA techniques.</b> Use authenticated plant material to develop highly reliable DNA tests.</b> Carefully define where, when and how to collect the reference species to be used as “certified” controls to validate DNA methods. <b> Develop the ability to identify unknown species.</b></p> </div> </div> </div> </div> </div> <div class="card-col"> <div class="card-bg"> <div class="card-bg-wrapper"> <div class="img-zone"> <div class="img-wrapper"> <div class="img-mask"> <img class="lazy" data-src="https://www.indena.com/indena_files/2020/12/label.jpg" alt="The Indena DNA label"> </div> </div> </div> <div class="text-zone" data-aos="fade-up" data-aos-duration="1000" > <h2>The Indena DNA label</h2> <p>INDENA GENETICALLY CERTIFIES THE PLANTS IT USES</p> <div class="paragraph"> <p>In consideration of the importance of plant DNA testing within the Indena quality system, and in order to communicate such analyses in a way that is more immediate and easy to use by clients, Indena developed the specific IN-DNA logo</p> </div> </div> </div> </div> </div> </div> </div> </section> <section id="part_15" class="text-image-block padding-top padding-bottom offset-left offset-right grey specular " data-bg="grey" > <div class="text-image-block-wrapper"> <div class="text negative"> <div class="text-content" data-aos="fade-up" data-aos-duration="1000"> <h3>DNA BARCODING: Plants & Extracts</h3> </div> </div> <div class="image"> <div class="image-wrapper"> <img class="lazy" data-src="https://www.indena.com/indena_files/2021/01/Dna-verified_extra_Q.jpg" alt="DNA BARCODING: Plants & Extracts"> <div class="img-loader"></div> </div> </div> </div> </section> <section id="part_16" class="banner-download padding-bottom offset-left offset-right white" data-bg="white" > <div class="banner-download-wrapper"> <div class="container-fluid"> <div class="row"> <div class="col-12 col-md-3 image-wrapper"> <img src="https://www.indena.com/indena_files/2021/01/catalogo-generico.png" alt="VERIFIED PLANT & EXTRACT Whitepaper"> </div> <div class="col-12 col-md-9 col-lg-8 content-wrapper"> <div class="content"> <div class="text" data-aos="fade-up" data-aos-duration="1000"> <h2>VERIFIED PLANT & EXTRACT Whitepaper</h2> </div> <div class="cta"> <div class="btn-wrapper" data-aos="fade-up" data-aos-duration="1000"> <div class="wd-button-wrapper"> <a id="open-filebanner-16-1" role="link" class="wd-button primary" href="https://www.indena.com/indena_files/2021/01/Verified_plant_extract.pdf" target="_blank"> <span class="button-label">Download</span> <svg class="icon"><use xlink:href="https://www.indena.com/indena_theme/assets/svg/wd-sprite.svg#wd-download"></use></svg> </a> </div> </div> </div> </div> </div> </div> </div> </div> </section> <section id="part_17" class="text-image-block small-padding-bottom-desk offset-left offset-right white " data-bg="white" > <div class="text-image-block-wrapper"> <div class="text positive"> <div class="text-content" data-aos="fade-up" data-aos-duration="1000"> <div class="pre-title">THE CHALLENGE</div> <h3>DNA Testing Of Extracts</h3> <p>First application: MIRTOSELECT® - Bilberry Extract<br /> The key to our method's success is that the amplified region must be univocal for Vaccinium myrtillus.<br /> <br /> </p> </div> </div> <div class="image"> <div class="image-wrapper"> <img class="lazy" data-src="https://www.indena.com/indena_files/2021/01/DNA-box-lg.jpg" alt="DNA Testing Of Extracts"> <div class="img-loader"></div> </div> </div> </div> </section> <section id="part_18" class="video padding-top offset-left offset-right grey" data-bg="grey" > <div class="video-wrapper"> <div class="wd-video"> <div class="video-wrapper"> <iframe src="https://www.youtube-nocookie.com/embed/LCTjXlRjbLA?rel=0&fs=1" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe> </div> </div> </div> </section> <div id="part_19" class="h2-anchor-wrapper padding-top small-padding-bottom-desk offset-left offset-right" data-bg="white"> <h2 class="js-anchor" id="section_19">bCUBE</h2> </div> <section id="part_20" class="text-image-block small-padding-bottom-desk offset-left offset-right white " data-bg="white" > <div class="text-image-block-wrapper"> <div class="text positive"> <div class="text-content" data-aos="fade-up" data-aos-duration="1000"> <div class="pre-title">One step beyond</div> <h3>On-Site DNA Analysis</h3> <p><p>Indena holds preferential access to breakthrough technology <br /> for the on-site identification of botanical species, exclusively for the food supplement ingredient industry.<br /> <br>The device that makes this possible is the bCUBE®*, made by Hyris Ltd.<br>Through an exclusive agreement, <strong>and drawing from the solid Indena database of references Indena has compiled over decades, DNA fingerprint analysis on plant samples can be carried out <br /> in the field, even by unskilled personnel.</strong></p><br /> <br /> <br /> <p><i>*bCUBE® courtesy of Hyris Ltd</i><p></p> </div> </div> <div class="image"> <div class="image-wrapper"> <img class="lazy" data-src="https://www.indena.com/indena_files/2021/01/bCUBE-CC-box-lg.jpg" alt="On-Site DNA Analysis"> <div class="img-loader"></div> </div> </div> </div> </section> <section id="part_21" class="banner padding-top negative-bottom offset-left offset-right white" data-bg="white" > <div class="banner-wrapper"> <div class="banner-content"> <div class="img-wrapper"> <img class="lozad" src="https://www.indena.com/indena_files/2020/12/banner-footer-theverde-lg.jpg" alt="On-Site DNA Analysis"> </div> <div class="container banner-text"> <div class="row"> <div class="col-10 offset-1 col-lg-6 offset-lg-6" data-aos="fade-up" data-aos-duration="1000"> <img class="banner-logo" src="https://www.indena.com/indena_files/2019/12/indena_logo-w.svg" alt="indena_logo-w"> <h2>Do you need to get in touch?</h2> <p>We are always happy to help with any queries on our products, services or general enquiries. 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data-validation-error-msg-required="Please insert an email" data-validation-error-msg-email="Please insert a valid email"> </div> <div class="col-12 mb-4"> <label for="about">Business Area*</label> <select class="select-custom" name="area_file" id="area_file" aria-required="true" aria-invalid="false" data-validation="required" data-validation-error-msg-required="This field is required"> <option value="" selected="selected" disabled>Select area of interest</option> <option value="1">Sales</option> <option value="2">Marketing</option> <option value="3">Custom Development</option> <option value="4">R&D / Scientific</option> <option value="5">Procurement</option> </select> </div> <div class="col-12 col-lg-6 mb-4"> <label for="f-role">Company Role*</label> <select class="select-custom searchable" name="role_file" id="role_file" aria-required="true" aria-invalid="false" data-validation="required" data-validation-error-msg-required="This field is required"> <option value="" selected="selected" disabled>Select your company role</option> <option value="Z010">Journalist</option> <option value="Z011">Media/Adv Sales</option> <option value="Z012">Researcher</option> <option value="Z013">College/University rep</option> <option value="Z014">Student</option> <option value="Z015">Employee</option> <option value="Z016">AD</option> </select> </div> <div class="col-12 col-lg-6 mb-4"> <label for="f-country">Country*</label> <select class="select-custom searchable" name="country_file" id="country_file" aria-required="true" aria-invalid="false" data-validation="required" data-validation-error-msg-required="This field is required"> <option value="" selected="selected" disabled>Select the country/region</option> <optgroup label="AFRICA"> <option value="ALGERIA" data-receiver="frank.cescon@indena.com">ALGERIA</option> <option value="ANGOLA" data-receiver="marco.lattanzi@indena.com">ANGOLA</option> <option value="CAMERUN" data-receiver="marco.lattanzi@indena.com">CAMERUN</option> <option value="CONGO REP.DEM." data-receiver="marco.lattanzi@indena.com">CONGO REP.DEM.</option> <option value="COTE D'IVOIRE" data-receiver="marco.lattanzi@indena.com">COTE D'IVOIRE</option> <option value="EGYPT" data-receiver="marco.lattanzi@indena.com">EGYPT</option> <option value="ETIOPIA" data-receiver="marco.lattanzi@indena.com">ETIOPIA</option> <option value="KENYA" data-receiver="marco.lattanzi@indena.com">KENYA</option> <option value="LIBIA" data-receiver="marco.lattanzi@indena.com">LIBIA</option> <option value="MADAGASCAR" data-receiver="marco.lattanzi@indena.com">MADAGASCAR</option> <option value="MOROCCO" data-receiver="frank.cescon@indena.com">MOROCCO</option> <option value="MAURITIUS" data-receiver="edwin.heavisides@indena.com">MAURITIUS</option> <option value="MOZAMBIQUE" data-receiver="marco.lattanzi@indena.com">MOZAMBIQUE</option> <option value="NAMIBIA" data-receiver="marco.lattanzi@indena.com">NAMIBIA</option> <option value="SIERRA LEONE" data-receiver="marco.lattanzi@indena.com">SIERRA LEONE</option> <option value="SOMALIA" data-receiver="marco.lattanzi@indena.com">SOMALIA</option> <option value="SRI LANKA" data-receiver="edwin.heavisides@indena.com">SRI LANKA</option> <option value="SUDAN" data-receiver="marco.lattanzi@indena.com">SUDAN</option> <option value="TANZANIA" data-receiver="marco.lattanzi@indena.com">TANZANIA</option> <option value="TOGO" data-receiver="marco.lattanzi@indena.com">TOGO</option> <option value="TUNISIA" data-receiver="frank.cescon@indena.com">TUNISIA</option> <option value="ZAMBIA" data-receiver="marco.lattanzi@indena.com">ZAMBIA</option> <option value="ZIMBAWE" data-receiver="marco.lattanzi@indena.com">ZIMBAWE</option> </optgroup> <optgroup label="ASIA"> <option value="AFGHANISTAN" data-receiver="marco.lattanzi@indena.com">AFGHANISTAN</option> <option value="ARABIA SAUDITA" data-receiver="diego.barral@indena.com">ARABIA SAUDITA</option> <option value="ARMENIA" data-receiver="diego.barral@indena.com">ARMENIA</option> <option value="BANGLADESH" data-receiver="edwin.heavisides@indena.com">BANGLADESH</option> <option value="CAMBODIA" data-receiver="edwin.heavisides@indena.com">CAMBODIA</option> <option value="CHINA" data-receiver="federico.debattista@indena.com">CHINA</option> <option value="ARAB EMIRATES" data-receiver="diego.barral@indena.com">ARAB EMIRATES</option> <option value="PHILIPPINES" data-receiver="edwin.heavisides@indena.com">PHILIPPINES</option> <option value="JAPAN" data-receiver="federico.debattista@indena.com">JAPAN</option> <option value="JORDAN" data-receiver="diego.barral@indena.com">JORDAN</option> <option value="HONG KONG (CHINA)" data-receiver="federico.debattista@indena.com">HONG KONG (CHINA)</option> <option value="INDIA" data-receiver="diego.barral@indena.com">INDIA</option> <option value="INDONESIA" data-receiver="edwin.heavisides@indena.com">INDONESIA</option> <option value="IRAN" data-receiver="diego.barral@indena.com">IRAN</option> <option value="IRAQ" data-receiver="diego.barral@indena.com">IRAQ</option> <option value="ISRAEL" data-receiver="diego.barral@indena.com">ISRAEL</option> <option value="KUWAIT" data-receiver="diego.barral@indena.com">KUWAIT</option> <option value="LAOS" data-receiver="edwin.heavisides@indena.com">LAOS</option> <option value="LEBANON" data-receiver="diego.barral@indena.com">LEBANON</option> <option value="MALESIA" data-receiver="martina.aisoni@indena.com">MALESIA</option> <option value="MONGOLIA" data-receiver="edwin.heavisides@indena.com">MONGOLIA</option> <option value="MYANMAR" data-receiver="edwin.heavisides@indena.com">MYANMAR</option> <option value="NEPAL" data-receiver="edwin.heavisides@indena.com">NEPAL</option> <option value="PAKISTAN" data-receiver="diego.barral@indena.com">PAKISTAN</option> <option value="PALESTINIAN TERRITORY" data-receiver="diego.barral@indena.com">PALESTINIAN TERRITORY</option> <option value="RUSSIAN FEDERATION" data-receiver="diego.barral@indena.com">RUSSIAN FEDERATION</option> <option value="SINGAPORE" data-receiver="edwin.heavisides@indena.com">SINGAPORE</option> <option value="SYRIA" data-receiver="diego.barral@indena.com">SYRIA</option> <option value="SOUTH KOREA" data-receiver="diego.barral@indena.com">SOUTH KOREA</option> <option value="SWEDEN" data-receiver="marco.lattanzi@indena.com">SWEDEN</option> <option value="THAILAND" data-receiver="martina.aisoni@indena.com">THAILAND</option> <option value="TAIWAN" data-receiver="edwin.heavisides@indena.com">TAIWAN</option> <option value="TAJIKISTAN" data-receiver="diego.barral@indena.com">TAJIKISTAN</option> <option value="TURKMENISTAN" data-receiver="diego.barral@indena.com">TURKMENISTAN</option> <option value="UZBEKISTAN" data-receiver="diego.barral@indena.com">UZBEKISTAN</option> <option value="VIETNAM" data-receiver="martina.aisoni@indena.com">VIETNAM</option> <option value="YEMEN" data-receiver="diego.barral@indena.com">YEMEN</option> <option value="BAHREIN" data-receiver="diego.barral@indena.com">BAHREIN</option> </optgroup> <optgroup label="CENTRAL AMERICA"> <option value="COSTA RICA" data-receiver="diego.barral@indena.com">COSTA RICA</option> <option value="CUBA" data-receiver="diego.barral@indena.com">CUBA</option> <option value="EL SALVADOR" data-receiver="diego.barral@indena.com">EL SALVADOR</option> <option value="JAMAICA" data-receiver="diego.barral@indena.com">JAMAICA</option> <option value="MEXICO" data-receiver="diego.barral@indena.com">MEXICO</option> <option value="NICARAGUA" data-receiver="diego.barral@indena.com">NICARAGUA</option> <option value="PANAMA " data-receiver="diego.barral@indena.com">PANAMA </option> <option value="DOMINICANAN REPUBLIC" data-receiver="diego.barral@indena.com">DOMINICANAN REPUBLIC</option> </optgroup> <optgroup label="EUROPE"> <option 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