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ERCIM News 104

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Roeland Merks, CWI, The Netherlands<br /> - Marie-France Sagot, Inria</p> <p>This issue in <a href="/images/stories/EN104/EN104-web.pdf" title="ERCIM News 104" >pdf</a>(56 pages)</p> </div> </div> </div></div></div> </div> <div class=" col-lg-9 col-md-9 col-sm-12 col-xs-12"> <div class="t3-module module " id="Mod276"><div class="module-inner"><div class="module-ct"><div class="swiper-container swiper-layout-over " id="sliderck276" dir="ltr" data-effect="slide"> <div class="swiper-wrapper"> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/en140-short.jpg')"> <img class="swiper-img" alt="" src="/images/stories/en140-short.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en140"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN139-short.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN139-short.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en139"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN138-short.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN138-short.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en138"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN137-short.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN137-short.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en137"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN136-short.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN136-short.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en136"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN135/cover.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN135/cover.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en135"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN134/cover.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN134/cover.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en134"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/EN133/cover.jpg')"> <img class="swiper-img" alt="" src="/images/stories/EN133/cover.jpg" /> </figure> <a aria-label="" class=" swiper-link" href="/en133"></a> </div> <div class="swiper-slide"> <figure class="swiper-img-cont" style="background-image:url('/images/stories/past-issues.png')"> <img class="swiper-img" alt="Back Issues Online" src="/images/stories/past-issues.png" /> </figure> <div class="swiper-caption"> <div class="swiper-title"> Back Issues Online </div> </div> <a aria-label="Back Issues Online" class=" swiper-link" href="/back-issues-online"></a> </div> </div> <div class="swiper-button-next"></div> <div class="swiper-button-prev"></div> </div> </div></div></div><div class="t3-module module " id="Mod165"><div class="module-inner"><h3 class="module-title "><span>Contents</span></h3><div class="module-ct"><ul class="nav nav-pills nav-stacked menusubmenu"> <li class="item-2198 parent"><a href="/en104/r-s" class="">Research and Society</a></li><li class="item-2177 parent"><a href="/en104/special" class="">Special Theme</a></li><li class="item-2206 parent"><a href="/en104/r-i" class="">Research and Innovation</a></li><li class="item-2214 parent"><a href="/en104/jea" class="">Joint ERCIM Actions</a></li><li class="item-2217 parent"><a href="/en104/books" class="">Books</a></li><li class="item-2219 parent"><a href="/en104/ib" class="">In Brief</a></li></ul> </div></div></div> </div> </div> <!-- SPOTLIGHT --> </div> </div> <!-- //SPOTLIGHT 1 --> <div id="t3-mainbody" class="container t3-mainbody"> <div class="row"> <!-- MAIN CONTENT --> <div id="t3-content" class="t3-content col-xs-12 col-sm-8 col-sm-push-4 col-md-9 col-md-push-3"> <div class="blog-featured" itemscope itemtype="https://schema.org/Blog"> <div class="items-leading clearfix "> <div class="leading leading-0" itemprop="blogPost" itemscope itemtype="https://schema.org/BlogPosting"> <!-- Article --> <article> <header class="article-header clearfix"> <h2 class="article-title" itemprop="headline"> <a href="/en104/special/tackling-big-data-in-the-life-sciences-introduction-to-the-special-theme" itemprop="url" title="Tackling Big Data in the Life Sciences - Introduction to the Special Theme"> Tackling Big Data in the Life Sciences - Introduction to the Special Theme</a> </h2> </header> <!-- Aside --> <aside class="article-aside clearfix"> <dl class="article-info muted"> <dt class="article-info-term"> Details </dt> <dd class="category-name hasTooltip" title="Category: "> <i class="fa fa-folder-open"></i> <a href="/en104/special" ><span itemprop="genre">Special Theme</span></a> </dd> <dd class="published hasTooltip" title="Published: "> <i class="icon-calendar"></i> <time datetime="2016-01-13T14:46:17+00:00" itemprop="datePublished"> 13 January 2016 </time> </dd> <dd class="modified"> <i class="fa fa-clock-o"></i> <time datetime="2016-01-14T10:12:35+00:00" itemprop="dateModified"> Last Updated: 14 January 2016 </time> </dd> <dd class="hits"> <i class="fa fa-eye"></i> <meta itemprop="interactionCount" content="UserPageVisits:6735" /> Hits: 6735 </dd> </dl> </aside> <!-- //Aside --> <section class="article-intro clearfix"> <p><img src="/images/stories/EN104/special.jpg" border="0" alt="special theme" width="207" height="128" style="float: left; margin: 0px 10px 10px 0px;" /></p> <p>by the guest editors Roeland Merks and Marie-France Sagot</p> <p>The Life Sciences are traditionally a descriptive science, in which both data collection and data analysis both play a central role. The latest decennia have seen major technical advances, which have made it possible to collect biological data at an unprecedented scale. Even more than the speed at which new data are acquired, the very complexity of what they represent makes it particularly difficult to make sense of them. Ultimately, biological data science should further the understanding of biological mechanisms and yield useful predictions, to improve individual health care or public health or to predict useful environmental interferences.</p> </section> <!-- footer --> <!-- //footer --> <section class="readmore"> <a class="btn btn-default" href="/en104/special/tackling-big-data-in-the-life-sciences-introduction-to-the-special-theme"> <span> Read more &hellip; </span> </a> </section> </article> <!-- //Article --> </div> <div class="leading leading-1" itemprop="blogPost" itemscope itemtype="https://schema.org/BlogPosting"> <!-- Article --> <article> <header class="article-header clearfix"> <h2 class="article-title" itemprop="headline"> <a href="/en104/r-s/because-it-s-2016-introduction-to-the-section-women-in-ict-research-and-education" itemprop="url" title="“Because it’s 2016” - Introduction to the section &quot;Women in ICT Research and Education&quot;"> “Because it’s 2016” - Introduction to the section &quot;Women in ICT Research and Education&quot;</a> </h2> </header> <!-- Aside --> <aside class="article-aside clearfix"> <dl class="article-info muted"> <dt class="article-info-term"> Details </dt> <dd class="category-name hasTooltip" title="Category: "> <i class="fa fa-folder-open"></i> <a href="/en104/r-s" ><span itemprop="genre">Research and Society</span></a> </dd> <dd class="published hasTooltip" title="Published: "> <i class="icon-calendar"></i> <time datetime="2016-01-13T15:14:33+00:00" itemprop="datePublished"> 13 January 2016 </time> </dd> <dd class="modified"> <i class="fa fa-clock-o"></i> <time datetime="2016-01-14T10:09:36+00:00" itemprop="dateModified"> Last Updated: 14 January 2016 </time> </dd> <dd class="hits"> <i class="fa fa-eye"></i> <meta itemprop="interactionCount" content="UserPageVisits:6852" /> Hits: 6852 </dd> </dl> </aside> <!-- //Aside --> <section class="article-intro clearfix"> <p><img src="/images/stories/EN104/berg3.jpg" border="0" alt="Lynda Hardman" width="207" height="128" style="float: left; margin: 0px 10px 10px 0px;" /></p> <p>by the guest editor Lynda Hardman</p> <p>The informatics and mathematics communities suffer from an affliction common to many technical and scientific fields, that fewer than 30% of those who choose to study and continue their profession in the field are women. This leads to a masculine-oriented culture that unwittingly discriminates against women.</p> </section> <!-- footer --> <!-- //footer --> <section class="readmore"> <a class="btn btn-default" href="/en104/r-s/because-it-s-2016-introduction-to-the-section-women-in-ict-research-and-education"> <span> Read more &hellip; </span> </a> </section> </article> <!-- //Article --> </div> </div> <div class="items-row cols-1 row-0 row"> <div class="item column-1 col-md-12"> <!-- Article --> <article> <header class="article-header clearfix"> <h2 class="article-title" itemprop="headline"> <a href="/en104/special/networks-to-the-rescue-from-big-omics-data-to-targeted-hypotheses" itemprop="url" title="Networks to the Rescue – From Big “Omics” Data to Targeted Hypotheses"> Networks to the Rescue – From Big “Omics” Data to Targeted Hypotheses</a> </h2> </header> <!-- Aside --> <aside class="article-aside clearfix"> <dl class="article-info muted"> <dt class="article-info-term"> Details </dt> <dd class="category-name hasTooltip" title="Category: "> <i class="fa fa-folder-open"></i> <a href="/en104/special" ><span itemprop="genre">Special Theme</span></a> </dd> <dd class="published hasTooltip" title="Published: "> <i class="icon-calendar"></i> <time datetime="2016-01-13T14:45:10+00:00" itemprop="datePublished"> 13 January 2016 </time> </dd> <dd class="modified"> <i class="fa fa-clock-o"></i> <time datetime="2016-01-14T09:53:05+00:00" itemprop="dateModified"> Last Updated: 14 January 2016 </time> </dd> <dd class="hits"> <i class="fa fa-eye"></i> <meta itemprop="interactionCount" content="UserPageVisits:6632" /> Hits: 6632 </dd> </dl> </aside> <!-- //Aside --> <section class="article-intro clearfix"> <p>by Gunnar Klau</p> <p>CWI researchers are developing the Heinz family of algorithms to explore big life sciences data in the context of biological networks. Their methods recently pointed to a novel hypothesis about how viruses hijack signalling pathways.</p> </section> <!-- footer --> <!-- //footer --> <section class="readmore"> <a class="btn btn-default" href="/en104/special/networks-to-the-rescue-from-big-omics-data-to-targeted-hypotheses"> <span> Read more &hellip; </span> </a> </section> </article> <!-- //Article --> </div> </div> <div class="items-row cols-1 row-1 row"> <div class="item column-1 col-md-12"> <!-- Article --> <article> <header class="article-header clearfix"> <h2 class="article-title" itemprop="headline"> <a href="/en104/special/interactive-pay-as-you-go-integration-of-life-science-data-the-humit-approach" itemprop="url" title="Interactive Pay-As-You-Go-Integration of Life Science Data: The HUMIT Approach"> Interactive Pay-As-You-Go-Integration of Life Science Data: The HUMIT Approach</a> </h2> </header> <!-- Aside --> <aside class="article-aside clearfix"> <dl class="article-info muted"> <dt class="article-info-term"> Details </dt> <dd class="category-name hasTooltip" title="Category: "> <i class="fa fa-folder-open"></i> <a href="/en104/special" ><span itemprop="genre">Special Theme</span></a> </dd> <dd class="published hasTooltip" title="Published: "> <i class="icon-calendar"></i> <time datetime="2016-01-13T14:42:35+00:00" itemprop="datePublished"> 13 January 2016 </time> </dd> <dd class="modified"> <i class="fa fa-clock-o"></i> <time datetime="2016-01-14T09:54:12+00:00" itemprop="dateModified"> Last Updated: 14 January 2016 </time> </dd> <dd class="hits"> <i class="fa fa-eye"></i> <meta itemprop="interactionCount" content="UserPageVisits:6890" /> Hits: 6890 </dd> </dl> </aside> <!-- //Aside --> <section class="article-intro clearfix"> <p>by Christoph Quix, Thomas Berlage and Matthias Jarke</p> <p>Biomedical research applies data-intensive methods for drug discovery, such as high-content analysis, in which a huge amount of substances are investigated in a completely automated way. The increasing amount of data generated by such methods poses a major challenge for the integration and detailed analysis of the data, since, in order to gain new insights, the data need to be linked to other datasets from previous studies, similar experiments, or external data sources. Owing to its heterogeneity and complexity, however, the integration of research data is a long and tedious task. The HUMIT project aims to develop an innovative methodology for the integration of life science data, which applies an interactive and incremental approach.</p> </section> <!-- footer --> <!-- //footer --> <section class="readmore"> <a class="btn btn-default" href="/en104/special/interactive-pay-as-you-go-integration-of-life-science-data-the-humit-approach"> <span> Read more &hellip; </span> </a> </section> </article> <!-- //Article --> </div> </div> <section class="items-more"> <h3>More Articles &hellip;</h3> <ol class="nav"> <li> <a href="/en104/special/eliminating-blind-spots-in-genetic-variant-discovery"> Eliminating Blind Spots in Genetic Variant Discovery</a> </li> <li> <a href="/en104/special/computational-estimation-of-chromosome-structure"> Computational Estimation of Chromosome Structure</a> </li> <li> <a href="/en104/special/modelling-approaches-to-inform-the-control-and-management-of-invasive-seaweeds"> Modelling Approaches to Inform the Control and Management of Invasive Seaweeds</a> </li> <li> <a href="/en104/special/kbdock-searching-and-organising-the-structural-space-of-protein-protein-interactions"> Kbdock – Searching and Organising the Structural Space of Protein-Protein Interactions</a> </li> <li> <a href="/en104/special/the-source-of-the-data-flood-sequencing-technologies"> The Source of the Data Flood: Sequencing Technologies</a> </li> <li> <a href="/en104/special/big-data-in-support-of-the-digital-cancer-patient"> Big Data in Support of the Digital Cancer Patient</a> </li> <li> <a href="/en104/special/towards-an-on-board-personal-data-mining-framework-for-p4-medicine"> Towards an On-board Personal Data Mining Framework For P4 Medicine</a> </li> <li> <a href="/en104/special/can-data-driven-self-management-reduce-low-back-pain"> Can Data-driven Self-Management Reduce Low Back Pain?</a> </li> <li> <a href="/en104/special/twitter-can-help-to-find-adverse-drug-reactions"> Twitter can Help to Find Adverse Drug Reactions</a> </li> <li> <a href="/en104/special/trust-for-the-doctor-in-the-loop"> Trust for the “Doctor in the Loop”</a> </li> <li> <a href="/en104/special/big-data-takes-on-prostate-cancer"> Big Data Takes on Prostate Cancer</a> </li> <li> <a href="/en104/special/mining-electronic-health-records-to-validate-knowledge-in-pharmacogenomics"> Mining Electronic Health Records to Validate Knowledge in Pharmacogenomics</a> </li> <li> <a href="/en104/special/modelling-the-growth-of-blood-vessels-in-health-and-disease"> Modelling the Growth of Blood Vessels in Health and Disease</a> </li> <li> <a href="/en104/special/modelling-using-standards-can-help-you"> Modelling? 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