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Independentei, No. 202, sector 6, 060021 Bucharest, Romania, director proiect Florin Oancea</p> <p>P1, Universitatea de ?tiin?e Agronomice ?i Medicin? Veterinar?.Bd. Marasti nr. 59, sector 1, 011464 Bucharest, responsabil proiect Prof. dr. Petru?a C?lina Cornea,</p> <p>P2, PolitechnikaWroc?awska, WybrzezeWyspanskiego 27, 50-370 Wroclaw, Poland, dr. KarolLeluk, AssistantProfessor, responsabil proiect</p> <p>P3, NorGenoTech AS, dr. Sergey Shaposhnikov, responsabil proiect</p> <p>P4, Laboratoarele Medica Srl, str. Frasinului nr. 11, 075100 Otopeni, Ilfov, Romania, dr. Ionu? Moraru, responsabil proiect</p> <p>P5, MKF-Ergis Sp. z o.o., ul. Tamka 16, 00-349 Warsaw, Poland, dr. Krzysztof Garman, responsabil proiect</p> </div> </div> </div> <div class="accordion-group"> <div class="accordion-heading"> <a href="#demoaccordion2" data-parent="#demoaccordion" data-toggle="collapse" class="accordion-toggle"> Obiective</a> </div> <div class=" collapse" id="demoaccordion2"> <div class="accordion-inner" align="justify"> <p>Dezvoltarea modelelor experimentale pentru:</p> <p>(a) consor?ii microbiene multifunc?ionale cu rol &icirc;n ob?inerea de componente cu valoare ad?ugat? mare din subprodusele agro-alimentare bogate &icirc;n fitosiliciu;</p> <p>(b) recuperarea ingredientelor bioactive din subprodusele alimentare ?i formularea lor "smart", cu r?spuns specific la factorii de mediu;</p> <p>(c) ob?inerea nanocelulozei ?i caracterizarea acesteia;</p> <p>Protejarea drepturilor de proprietate pentru solu?iile tehnice noi, referitoare la consor?iile multifunc?ionale, inclusiv cele simbiotice de bacterii ?i drojdii (SCOBY) ?i la formularea &rdquo;smart&rdquo; a ingredientelor active recuperate din subprodusele alimentare;</p> <p>Diseminarea rezultatelor ob?inute.</p> </div> </div> </div> <div class="accordion-group"> <div class="accordion-heading"> <a href="#demoaccordion3" data-parent="#demoaccordion" data-toggle="collapse" class="accordion-toggle"> Rezultate</a> </div> <div class=" collapse" id="demoaccordion3"> <div class="accordion-inner" align="justify"> <p>S-au selectat 2 tulpini fungice care solubilizeaz? fitosiliciul ?i au ac?iune de biostimulant de cre?tere, pe baza c?rora s-au realizat dou? consor?ii fugi &ndash; bacterii care au fost brevetate</p> <p>S-a demonstrat cre?terea biodisponibilit??ii fitosiliciului din diferite materiale vegetale bogate &icirc;n fitosiliciu prin fermentare cu Kombucha &ndash; consor?ii simbiotice de drojdii ?i bacterii.&nbsp;</p> <p>Ob?inerea nanocelulozei bacteriene din membrane de Kombucha: a) purificare alcalina, m?run?ire cu blender, urmata de m?run?ire avansata cu moara coloidala; b) purificare urmata de atomizare pentru ob?inerea de BNC in forma uscata; c) purificare, urmata de microfluidizare la presiune ridicata (1300 bar).</p> <p><img src="../uploads/images/untitled_5c0686afefea6.jpg" alt="" width="691" height="518" /></p> </div> </div> </div> <div class="accordion-group"> <div class="accordion-heading"> <a href="#demoaccordion4" data-parent="#demoaccordion" data-toggle="collapse" class="accordion-toggle"> Indicatori de rezultat</a> </div> <div class=" collapse" id="demoaccordion4"> <div class="accordion-inner" align="justify"> <p><strong>4 articole publicate</strong></p> <ol> <li><em>Synthesis of non-toxic silica particlesstabilizedby molecular complex oleic-acid/sodium oleate</em>, C. I. Sp?taru, R. Ianchi?, C. Petcu, C. L. Nistor *, V. Purcar, B. Trica, S. G. Nitu, R. Somoghi, E. Alexandrescu, F. Oancea, D. Donescu, <em>International Journal of Molecular Sciences</em>, 17(11), 1936; doi:10.3390/ijms17111936 (faIF = 3,257).</li> <li><em>The Influence of New Hydrophobic Silica Nanoparticles on the SurfaceProperties of the FilmsObtained from BilayerHybrids</em>.Petcu, C., Purcar, V., Sp?taru, C. I., Alexandrescu, E., ?omoghi, R., Tric?, B., Ni?u, S.G., Panaitescu, D.M, Donescu, D.&nbsp; &amp; Jecu, M. L. (2017). Nanomaterials, 7(2), 47. (IF=3,553),</li> <li><em>BacterialNanocellulose from Side-Streams of Kombucha Beverages Production: Preparation and Physical-Chemical Properties</em>, Dima, S. O., Panaitescu, D. M., Orban, C., Ghiurea, M., Doncea, S. M., Fierascu, R. C., Nistor, C.L, Alexandrescu, E., Nicolae, C.A., Tric?, B., Moraru, A. &amp; Oancea F. (2017).Polymers, 9(8), 374. (IF=3,364)</li> <li><em>Bee collectedpollen with enhanced healthbenefits, producedbyfermentation with a Kombucha consortium</em>, E. U?oiu, F. Matei, A. Toma, C. F. Digu??, L M. ?tefan, S. M?noiu, V. V. Vr?jma?u, I. Moraru, A. Oancea, F. Israel-Roming, C. P. Cornea, D. Constantinescu-Aruxandei, A. Moraru ?i F. Oancea, Nutrients, 10 (10), 1365 (IF&nbsp; = 4,196)</li> </ol> <p><strong>6 Cereri de brevet depuse</strong></p> <p>Au fost depuse&nbsp; cinci cereri de brevet na?ionale (OSIM) ?i o cerere de brevet interna?ional? (PCT/WIPO). Cererile de brevet na?ionale depuse se refer? la: procedeu pentru selec?ia consor?iilor de microorganisme, care produc amestecuri de enzime ?i/sau (poli)peptide care amplific? ac?iunea enzimelor, destinate etapelor ini?iale de biorafinare a materialului vegetal cu un con?inut ridicat de fito-siliciu (Activitatea AI.1, cerere de brevet a00948/29.11.2016, titular USAMV Bucure?ti); procedeu prin care se solubilizeaz? fitosiliciul din materialul vegetal (Activitate AI.2., cerere de brevete a00893/24.11.2016, titular INCDCP-ICECHIM); procedeu care include solu?ii originale de cultivare consor?ii SCOBY pentru cre?terea biodisponibilit??ii ingredientelor active din materialul vegetal cu un con?inut ridicat de siliciu (Activitate AI.3., cerere de brevet a00822/14.11.2016, titular Laboratoarele Medica); Cererea de brevet A 1010 din 29.11.20017, Compozi?ie sinbiotic? con?in&acirc;nd un consor?iu&nbsp; de microorganisme probiotice ?i procedeu de ob?inere, titular Laboratoare Medica, prin care se protejeaz? procedeul prin caeconsor?iul simbiotic de bacterii&nbsp; ?i drojdii, fermenteaz? glucidele extrase din material silicios cu producere de&nbsp; membran? de Kombucha din care se extrage nanoceluloza; Cererea de brevet A1015 din 04.12.2017, Consor?iu microbian multifunc?ional pentru solubilizarea fitosiliciului ?i procedeu pentru utilizarea acestuia, co-titulari INCDCP-ICECHIM ?i USAMVCererea de brevet interna?ional? se refer? la un procedeu de &icirc;ncapsulare a unor ingrediente active recuperate din materialul vegetal, &icirc;n sisteme pe baz? de particule de silice mezoporoas? ob?inut? din fito-siliciu, pentru realizarea unor produse&nbsp; care r?spund specific la factorii de mediu (cerere de brevet PCT/RO2016/000025 din 23.11.2016, titular INCDCP-ICECHIM).</p> </div> </div> </div> </div><!-- end accordion --> </div><!-- end .span7 --> </div><!-- end .row --> </div><!-- end .content_section --> </section> </div><!-- end #page --> <!-- // FOOTER // --> <div class="footer"> <div class="container"> <div class="row"> <div class="span9"> <br /><br /><br /> </div></div> <p align=center><font color="#CCCCCC">&nbsp;&nbsp;&copy; ICECHIM - All Rights Reserved</font></p> <center><a href="https://icechim.ro">https://icechim.ro</a></center> <br /><br /><br /> </div> </div><!-- end .footer --> </body> </html>

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