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</nav> <header class="container py-3"> <div class="row align-items-start"> <div class="col-lg-1 col-md-1 d-none d-sm-block"> <img src="https://www.hilarispublisher.com/admin/flyers/journal-of-genetics-and-dna-research-flyer.jpg" alt=".." title="haga clic aqu铆" class="img-fluid"> </div> <div class="col-lg col-md"> <h1 class="h2 text-primary">Revista de genética e investigación del ADN.</h1> <div class="row"> <div class="col"> <p class="mb-1">ISSN: 2684-6039 </p> </div> <div class="col"> Acceso abierto </div> <div class="nav-item dropdown multi_lang j_multi_lang"> <a class="nav-link dropdown-toggle" href="#" id="multi_lang" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">Language</a> <div class="dropdown-menu" aria-labelledby=""> <a class="dropdown-item" href="https://www.hilarispublisher.com/scholarly/epigenetics-journals-articles-ppts-list-1960.html" title="English"> <img src="https://www.hilarispublisher.com/admin/flags/usa.png">English </a> <a 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<h2 class="heading-1">Epigenética</h2> <p><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">La epigenética es el estudio de los cambios hereditarios en la expresión genética (genes activos versus inactivos) que no implican cambios en la secuencia de ADN subyacente (un cambio en el fenotipo sin un cambio en el genotipo), lo que a su vez afecta la forma en que las células leen los genes. </font><font style="vertical-align: inherit;">El cambio epigenético es un fenómeno regular y natural, pero también puede verse influido por varios factores, como la edad, el entorno/estilo de vida y el estado de la enfermedad. </font><font style="vertical-align: inherit;">Las modificaciones epigenéticas pueden manifestarse tan comúnmente como la forma en que las células se diferencian terminalmente para terminar como células de la piel, células del hígado, células del cerebro, etc. O bien, el cambio epigenético puede tener efectos más dañinos que pueden resultar en enfermedades como el cáncer. </font><font style="vertical-align: inherit;">Actualmente se considera que al menos tres sistemas, incluida la metilación del ADN, la modificación de histonas y el silenciamiento de genes asociados con ARN no codificante (ARNnc), inician y mantienen el cambio epigenético. </font></font><sup><a href="https://www.whatisepigenetics.com/fundamentals/#fn-12-1" id="fnref-12-1" onclick="return fdfootnote_show(12)"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">1</font></font></a></sup><font style="vertical-align: inherit;"><font style="vertical-align: inherit;"> Investigaciones nuevas y en curso descubren continuamente el papel de la epigenética en una variedad de trastornos humanos y enfermedades mortales.</font></font><img src="https://www.whatisepigenetics.com/wp-content/uploads/2013/07/dna-chromatin-histone.jpg" /></p> </div> <div class="col-12 col-sm-3"> <!--==========relevant topics==================--> <div class="mb-3"> 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