CINXE.COM

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recombinant-DNA", the other half jointly to Walter Gilbert and Frederick Sanger "for their contributions concerning the determination of base sequences in nucleic acids""> <meta itemprop="description" content="The Nobel Prize in Chemistry 1980 was divided, one half awarded to Paul Berg "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA", the other half jointly to Walter Gilbert and Frederick Sanger "for their contributions concerning the determination of base sequences in nucleic acids"" /> <meta property="og:description" content="The Nobel Prize in Chemistry 1980 was divided, one half awarded to Paul Berg "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA", the other half jointly to Walter Gilbert and Frederick Sanger "for their contributions concerning the determination of base sequences in nucleic acids"" />   <meta name="twitter:card" content="summary_large_image" /> 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<article class="page-content facts"> <header class="section-header border-top"> <h1> Frederick Sanger </h1> <h2>Facts</h2> </header> <select class="aside-navigation aside-navigation--mobile js-aside-navigation--mobile" name="Go to laureate page"> <option value="" selected disabled>Navigate to:</option> <option value="https://www.nobelprize.org/prizes/chemistry/1980/summary/"> Summary</option><optgroup label=" Laureates"><option value="https://www.nobelprize.org/prizes/chemistry/1980/berg/facts/">- Paul Berg</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/gilbert/facts/">- Walter Gilbert</option><optgroup label="- Frederick Sanger"><option value="https://www.nobelprize.org/prizes/chemistry/1980/sanger/facts/" disabled selected>-- Facts</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/sanger/biographical/">-- Biographical</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/sanger/lecture/">-- Nobel Lecture</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/sanger/speech/">-- Banquet speech</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/sanger/interview/">-- Interview</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/sanger/other-resources/">-- Other resources</option><option value="https://www.nobelprize.org/prizes/chemistry/1958/sanger/facts/">-- The Nobel Prize in Chemistry 1958</option></optgroup></optgroup><option value="https://www.nobelprize.org/prizes/chemistry/1980/press-release/"> Press release</option><option value="https://www.nobelprize.org/prizes/chemistry/1980/ceremony-speech/"> Award ceremony speech</option></select> <div class="image"> <picture ><source data-srcset="https://www.nobelprize.org/images/sanger-13323-portrait-mini-2x.jpg" media="(min-width: 220px)" /><source data-srcset="https://www.nobelprize.org/images/sanger-13323-portrait-small-2x.jpg" media="(min-width: 900px)" /><source data-srcset="https://www.nobelprize.org/images/sanger-13323-portrait-medium-2x.jpg" media="(min-width: 1400px)" /><img class="lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" alt="Frederick Sanger" /><noscript><img src="https://www.nobelprize.org/images/sanger-13323-portrait-medium.jpg" alt="Frederick Sanger" /></noscript></picture><figcaption class="figcaption"><p class="figcaption__attribution">Photo from the Nobel Foundation archive.</p></figcaption> </div> <div class="content"> <p> Frederick Sanger<br> The Nobel Prize in Chemistry 1980 </p> <p class="born-date">Born: 13 August 1918, Rendcombe, United Kingdom </p> <p class="dead-date">Died: 19 November 2013, Cambridge, United Kingdom </p> <p> Affiliation at the time of the award: MRC Laboratory of Molecular Biology, Cambridge, United Kingdom </p> <p> Prize motivation: “for their contributions concerning the determination of base sequences in nucleic acids” </p> <p> Prize share: 1/4 </p> <p> Also awarded: <a href="https://www.nobelprize.org/prizes/chemistry/1958/summary/">The Nobel Prize in Chemistry 1958</a> </p> </div> <div class="description border-top"> <h3> Life </h3> <p> <p>Frederick Sanger was born in the small village of Rendcomb, England. His father was a doctor. After having converted to quakerism he brought up his sons as quakers. Frederick Sanger studied and received his PhD at the University of Cambridge in 1943. He remained in Cambridge for the rest of his career. Frederick Sanger was married with three children.</p> </p> </div> <div class="description border-top"> <h3> Work </h3> <p> <p>An organism's genome is stored in the form of long rows of building blocks, known as nucleotides, which form DNA molecules. An organism's genome can be mapped by establishing the order of the nucleotides within the DNA molecule. In 1977, Frederick Sanger developed a method based on using small amounts of what are known as dideoxynucleotides. These can be inserted into the DNA chain, but at a certain nucleotide they stop growth of the chain so that fragments of different lengths are created. After undergoing what is known as electrophoresis, the nucleotide sequences in a DNA sample can be identified.</p> </p> </div> <footer class="border-top pagecite" itemscope itemtype="http://schema.org/citation"> <p> To cite this section <br> MLA style: Frederick Sanger – Facts. NobelPrize.org. Nobel Prize Outreach AB 2024. 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