Nijagal Lab - Homepage | UCSF Department of Surgery

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<ul class="menu"> <li class="menu-item"> <a href="https://acutecaresurgery.ucsf.edu/">Acute Care Surgery</a> </li> <li class="menu-item"> <a href="https://ctsurgery.ucsf.edu/">Cardiothoracic Surgery</a> </li> <li class="menu-item"> <a href="https://bariatricsurgery.ucsf.edu/">Bariatric Surgery</a> </li> <li class="menu-item"> <a href="https://breastcaresurgery.ucsf.edu/">Breast Care Surgery</a> </li> <li class="menu-item"> <a href="https://cardiacsurgery.ucsf.edu/">Cardiac Surgery</a> </li> <li class="menu-item"> <a href="https://herniacenter.ucsf.edu/">Center for Hernia Repair & Abdominal Wall Reconstruction</a> </li> <li class="menu-item"> <a href="https://limbpreservation.ucsf.edu/">Center for Limb Preservation & Diabetic Foot</a> </li> <li class="menu-item"> <a href="https://geriatricsurgery.ucsf.edu/">Center for Surgery in Older Adults</a> </li> <li class="menu-item"> <a href="https://colorectalsurgery.ucsf.edu/">Colorectal Surgery</a> </li> <li class="menu-item"> <a 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<a href="https://surgeryeducation.ucsf.edu/">Surgery Education Portal</a> </li> <li class="menu-item"> <a href="https://surgeryresearch.ucsf.edu/">Surgery Research Portal</a> </li> <li class="menu-item"> <a href="https://surgicalskillslab.ucsf.edu/">Surgical Skills Center</a> </li> <li class="menu-item"> <a href="https://thoracicsurgeryresidency.ucsf.edu/">Thoracic Surgery Residency</a> </li> <li class="menu-item"> <a href="https://t32surgicaloncology.ucsf.edu/">T32 Surgical Oncology</a> </li> <li class="menu-item"> <a href="https://t32transplantsurgery.ucsf.edu/">T32 Research Training in Transplant Surgery</a> </li> <li class="menu-item"> <a href="https://ucsf-eastbay.squarespace.com/">UCSF-East Bay General Surgery Residency</a> </li> <li class="menu-item"> <a href="https://vascularsurgeryresidency.ucsf.edu/">Vascular Surgery Integrated Residency Program</a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded"> <div role="group" aria-labelledby="ResearchWebsites" class="col"> <h2 id="ResearchWebsites" class="col-head" tabindex="0"> <span>Research Websites</span> </h2> <ul class="menu"> <li class="menu-item"> <a href="https://raffailab.ucsf.edu/">Atherosclerosis Research Lab</a> </li> <li class="menu-item"> <a href="https://surgerybiostat.ucsf.edu/">Biostatistics Core</a> </li> <li class="menu-item"> <a href="https://cardiacbiomechanicslab.ucsf.edu/">Cardiac Biomechanics Lab</a> </li> <li class="menu-item"> <a href="https://mindfulsurgeon.ucsf.edu/">Center for Mindfulness in Surgery</a> </li> <li class="menu-item"> <a href="https://livertissueengineering.ucsf.edu/">Chang Laboratory for Liver Tissue Engineering</a> </li> <li class="menu-item"> <a href="https://contelab.ucsf.edu/">Conte Lab</a> </li> <li class="menu-item"> <a href="https://endocrineneoplasialab.ucsf.edu/">Endocrine Neoplasia Research Lab</a> </li> <li class="menu-item"> <a href="https://itl.ucsf.edu/">Immunogenetics & Transplantation Lab</a> </li> <li class="menu-item"> <a 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36.5055C731.859 31.9703 699.904 31.62 640.079 29.427C538.688 25.7093 499.769 35.9695 395.448 39.8299C367.758 41.0886 325.915 34.1723 266.187 37.8121C206.459 41.4455 176.113 28.5776 114.057 30.5389C52 32.5003 35.5 37.8121 1 40.6103" stroke="#CACED2" stroke-miterlimit="10"/> <path d="M1441 74.8783C1323.58 74.8783 1257.6 69.6813 1172.61 61.0586C1104.74 54.1747 943.973 25.069 875.684 22.8695C685.557 16.7317 673.121 76.085 424.847 74.8783C213.911 68.1778 184.5 36.5007 116 15.5004C47.5 -5.5 1 3.12031 1 3.12031" stroke="#CACED2" stroke-miterlimit="10"/> </svg> </div> </div> <div class="content-carousel-card-content"> <div class="heading"> <div class="field field--name-field-heading field--type-string field--label-hidden field__item">Nijagal Lab</div> </div> </div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div class="columns text-vert-align--top remove-top-padding columns--layout-sidebar-left paragraph paragraph--type--kan-columns paragraph--view-mode--default no-decor"> <div class="columns__wrap"> <div class="columns__item-list"> <div class="columns__item columns-col1"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <article class="media media--type-image media--view-mode-rounded-overlay" aria-label="Image about amar nijagal 354x210"> <div class="corner-detail mobile"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="50px" height="50px" viewBox="0 0 50 50" style="enable-background:new 0 0 50 50;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,50 2.5,2.5 50,2.5 " /> </svg> </div> <div class="corner-detail desktop"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="100px" height="100px" viewBox="0 0 100 100" style="enable-background:new 0 0 100 100;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,100 2.5,2.5 100,2.5 " /> </svg> </div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/rounded_overlay/public/2024-10/amar-nijagal-md.webp?itok=30IwF2Uj" width="354" height="210" alt="amar nijagal 354x210" class="image-style-rounded-overlay"> </div> </article> <h3><a href="/bio/amar-nijagal-md" data-entity-type="node" data-entity-uuid="8583e53b-27dd-4064-bbb3-552092c0a156" data-entity-substitution="canonical">Amar Nijagal, MD</a></h3><p style="font-size:1rem;">Associate Professor of Surgery<br>Division of Pediatric Surgery<br>UCSF Benioff Children's Hospital, San Francisco</p> </div> </div> </div></div> <div class="columns__item columns-col2"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <h2 style="margin-top:0px;">Investigating How Immune Cells Regulate the Development and Repair of Fetal Organs</h2><div class="lab_content_textarea_top"><p>We study how immune cells may regulate the development and repair of fetal organs. Our research is currently focused on the development of the liver and bile ducts as the fetal liver is ripe with interactions between developing hepatocytes/cholangiocytes and the hematopoietic system. We are interested in identifying key relationships and interactions between immune cells and developing tissues in both the steady state and during fetal injury. Using advanced surgical techniques in mouse models, we are able to manipulate and induce injury in fetal organs. We also use “discovery”-based transcriptomic approaches and innovative bioengineering techniques to identify novel cell types and pathways that may serve as a link between the immune system and fetal liver development.</p><h3>Affiliations</h3><ul><li><a href="https://cancer.ucsf.edu/research/programs/pediatric-malignancies" target="_blank">HDFCC Pediatric Malignancies Program</a></li><li><a href="https://stemcell.ucsf.edu/" target="_blank">Broad Stem Cell Center</a></li></ul></div> </div> </div> </div></div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div class="columns text-vert-align--top remove-top-padding columns--layout-column-wider-right paragraph paragraph--type--kan-columns paragraph--view-mode--default"> <div class="field field--name-field-heading field--type-string field--label-hidden field__item">News Highlight</div> <div class="columns__wrap"> <div class="columns__item-list"> <div class="columns__item columns-col1"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <article class="media media--type-image media--view-mode-rounded-overlay" aria-label="Image about AASLD Foundation Logo with padding"> <div class="corner-detail mobile"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="50px" height="50px" viewBox="0 0 50 50" style="enable-background:new 0 0 50 50;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,50 2.5,2.5 50,2.5 " /> </svg> </div> <div class="corner-detail desktop"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="100px" height="100px" viewBox="0 0 100 100" style="enable-background:new 0 0 100 100;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,100 2.5,2.5 100,2.5 " /> </svg> </div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/rounded_overlay/public/2024-10/aasld-foundation-logo-padding.webp?itok=YiQy6TkV" width="1500" height="1000" alt="AASLD Foundation Logo with padding" class="image-style-rounded-overlay"> </div> </article> </div> </div> </div></div> <div class="columns__item columns-col2"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <div class="lab-fp-middle-content"><div dir="ltr"><p>We are pleased to announce that <a href="/bio/amar-nijagal-md" title="Amar Nijagal, M.D.">Amar Nijagal, MD</a> has been selected for the AASLD CTORA Award (American Association for the Study of Liver Diseases Foundation) for his proposal & work focused on hepatoblastoma. The award provides Dr. Nijagal with $200K of funding for 2 years and is intended to fund his research project entitled “Defining the role of tumor associated myeloid cells in pediatric hepatoblastoma.” This is a vital stepping stone for his lab & continuing science. For more information on the ASSLD CTORA Award, please visit <a href="http://www.aasldfoundation.org/" target="_blank">http://www.aasldfoundation.org/</a> </p></div></div> </div> </div> </div></div> </div> </div> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--small-cta paragraph--view-mode--default"> <div class="field field--name-field-title field--type-text field--label-hidden field__item"><h2>Twitter</h2></div> <div class="clearfix text-formatted field field--name-field-paragraph field--type-text-long field--label-hidden field__item"><div class="flex-items"><div class="twitter-copy">Please follow the link to Twitter to view the @UCSFPedSurgery Twitter site.</div><div class="twitter-icon"><img src="/sites/default/files/2024-08/twitter-icon_0.png"></div></div></div> <div class="field--name-field-link"> <a href="https://twitter.com/UCSFPedSurgery" aria-label="Follow us on Twitter">Follow us on Twitter</a> </div> </div> </div> <div class="field__item news-for-lab"> <div > <div class="columns text-vert-align--top remove-top-padding columns--layout-equal paragraph paragraph--type--kan-columns paragraph--view-mode--default"> <div class="columns__wrap"> <div class="columns__item-list"> <div class="columns__item columns-col1"> <div > <div class="filtered-list paragraph paragraph--type--kan-filtered-list paragraph--view-mode--default"> <div class="filtered-list__header"> <div class="filtered-list__title"> <h2>Featured News</h2> </div> </div> <div class="filtered-list__view"> <div class="field field--name-kan-field-views field--type-viewsreference field--label-hidden field__item"><div class="views-element-container"><div class="news-with-readmore view view-news-events view-id-news_events view-display-id-block_3 js-view-dom-id-b8975917a5d08652d23a0c23a6f098977cb11c8ddb045a0a63ba044494e62af1"> <div class="view-header"> <style> .news-with-readmore .more-link { margin-top: 18px; border: 2px solid #ccc; transition: all 0.6s ease 0s; display: inline-block; border-radius: 6.375rem; padding: 5px 10px; border-color: #052049; font-family: "Helvetica Neue Medium", "HelveticaNeue", "Helvetica", "Arial", sans-serif; line-height: 1.25; letter-spacing: 0; transition: all 0.6s ease 0s; display: inline-block; border-radius: 6.375rem; color: #fff; border: 0.125rem solid transparent; border-top-color: transparent; border-right-color: transparent; border-bottom-color: transparent; border-left-color: transparent; text-align: center; cursor: pointer; -webkit-user-select: none; -moz-user-select: none; user-select: none; text-decoration: none; -webkit-appearance: none; -moz-appearance: none; appearance: none; position: relative; font-size: 1rem; padding: 0.625rem 1.25rem; background-color: transparent; color: #14828c; border-color: #14828c; } .news-with-readmore .more-link:hover { color: #052049; border-color: #052049; } .news-with-readmore .more-link a { text-decoration:none;} .news-with-readmore .more-link a::before { content: ""; width: 100%; height: 100%; outline: 0.25rem solid transparent; position: absolute; top: 0; left: 0; border-radius: 30px; } .news-with-readmore .more-link a:hover::before { outline-color: #052049; } .row-with-icon .news-icon { width: 24px !important; display: inline-block; } .row-with-icon.views-row a { display: inline !important; padding-left: 7px; vertical-align: 4px; } </style> </div> <div class="view-content"> <div class="row-with-icon views-row"><img src='/sites/default/files/2024-10/news-icon-2.png' class='news-icon' /><a href="/news/dr-amar-nijagal-and-dr-adam-abate-have-received-funding-ucsf-program-breakthrough-biomedical" hreflang="en">Dr. Amar Nijagal and Dr. Adam Abate have received funding from the UCSF Program for Breakthrough Biomedical Research</a> </div> <div class="row-with-icon views-row"><img src='/sites/default/files/2024-10/news-icon-2.png' class='news-icon' /><a href="/news/department-surgery-faculty-recipients-academy-medical-educators-excellence-mentoring-award" hreflang="en">Department of Surgery Faculty Recipients of Academy of Medical Educators Excellence in Mentoring Award</a> </div> <div class="row-with-icon views-row"><img src='/sites/default/files/2024-10/news-icon-2.png' class='news-icon' /><a href="/news/dr-amar-nijagal-has-secured-two-prestigious-awards" hreflang="en">Dr. Amar Nijagal has secured two prestigious awards</a> </div> <div class="row-with-icon views-row"><img src='/sites/default/files/2024-10/news-icon-2.png' class='news-icon' /><a href="/news/department-surgery-staff-and-faculty-receive-2022-chancellor-awards-diversity" hreflang="en">Department of Surgery staff and faculty receive 2022 Chancellor Awards for Diversity</a> </div> </div> <div class="more-link"><a href="/news">View All News</a></div> </div> </div> </div> </div> </div> </div></div> <div class="columns__item columns-col2"> <div > <div class="filtered-list paragraph paragraph--type--kan-filtered-list paragraph--view-mode--default"> <div class="filtered-list__header"> <div class="filtered-list__title"> <h2>Featured Publications</h2> </div> </div> <div class="filtered-list__view"> <div class="field field--name-kan-field-views field--type-viewsreference field--label-hidden field__item"><div class="views-element-container"><div class="node--content node__content view view-publications-for-lab view-id-publications_for_lab view-display-id-block_2 js-view-dom-id-f5ed2bcc33cccf517cccce73c7b8c9e7ebbc8f373474d0d1137b965831ffb85a"> <div class="view-header"> <style> .node--content-pubs.node__content-pubs { margin: auto !important; width: 70% !important; } .node--content-pubs.node__content-pubs .item-list ol li { padding-bottom:.8rem; } .smal-size-font {font-size:11px;} .author-color {color:#0f388a;} </style><style> .item-list.pubs-outerlist { max-height: 560px; overflow: scroll; overflow-x: hidden; padding-right: 10px; overflow-y: auto; } .item-list.pubs-outerlist ol { margin-top: 0; } .view-publications-for-lab .more-link { margin-top: 18px; border: 2px solid #ccc; transition: all 0.6s ease 0s; display: inline-block; border-radius: 6.375rem; padding: 5px 10px; border-color: #052049; font-family: "Helvetica Neue Medium", "HelveticaNeue", "Helvetica", "Arial", sans-serif; line-height: 1.25; letter-spacing: 0; transition: all 0.6s ease 0s; display: inline-block; border-radius: 6.375rem; color: #fff; border: 0.125rem solid transparent; border-top-color: transparent; border-right-color: transparent; border-bottom-color: transparent; border-left-color: transparent; text-align: center; cursor: pointer; -webkit-user-select: none; -moz-user-select: none; user-select: none; text-decoration: none; -webkit-appearance: none; -moz-appearance: none; appearance: none; position: relative; font-size: 1rem; padding: 0.625rem 1.25rem; background-color: transparent; color: #14828c; border-color: #14828c; } .view-publications-for-lab .more-link:hover { color: #052049; border-color: #052049; } .view-publications-for-lab .more-link a { text-decoration:none;} .view-publications-for-lab .more-link a::before { content: ""; width: 100%; height: 100%; outline: 0.25rem solid transparent; position: absolute; top: 0; left: 0; border-radius: 30px; } .view-publications-for-lab .more-link a:hover::before { outline-color: #052049; } </style> </div> <div class="view-content"> <div class="item-list pubs-outerlist"> <ol> <li><span class="views-field views-field-title"><span class="field-content"><b>Immunology of Biliary Atresia.</b><br /></span></span><span class="views-field views-field-field-kup-publication-year"><span class="field-content">2025 | </span></span><span class="views-field views-field-field-kup-publication-id"><span class="field-content"> <a href="https://pubmed.ncbi.nlm.nih.gov/39862687">PubMed</a> </span></span></li> <li><span class="views-field views-field-title"><span class="field-content"><b>Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors.</b><br /></span></span><span class="views-field views-field-field-kup-publication-year"><span class="field-content">2024 | </span></span><span class="views-field views-field-field-kup-publication-id"><span class="field-content"> <a href="https://pubmed.ncbi.nlm.nih.gov/39229070">PubMed</a> </span></span></li> <li><span class="views-field views-field-title"><span class="field-content"><b>Index admission cholecystectomy for acute cholecystitis reduces 30-day readmission rates in pediatric patients.</b><br /></span></span><span class="views-field views-field-field-kup-publication-year"><span class="field-content">2023 | </span></span><span class="views-field views-field-field-kup-publication-id"><span class="field-content"> <a href="https://pubmed.ncbi.nlm.nih.gov/38114877">PubMed</a> </span></span></li> <li><span class="views-field views-field-title"><span class="field-content"><b>Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice.</b><br /></span></span><span class="views-field views-field-field-kup-publication-year"><span class="field-content">2023 | </span></span><span class="views-field views-field-field-kup-publication-id"><span class="field-content"> <a href="https://pubmed.ncbi.nlm.nih.gov/36615137">PubMed</a> </span></span></li> <li><span class="views-field views-field-title"><span class="field-content"><b>Advances in the Treatment of Neonatal Biliary Disease.</b><br /></span></span><span class="views-field views-field-field-kup-publication-year"><span class="field-content">2022 | </span></span><span class="views-field views-field-field-kup-publication-id"><span class="field-content"> <a href="https://pubmed.ncbi.nlm.nih.gov/36328612">PubMed</a> </span></span></li> </ol> </div> </div> <div class="more-link"><a href="/nijagal-lab-publications">View All Publications</a></div> </div> </div> </div> </div> </div> </div></div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div 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