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type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_21"); </script> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_22"); </script>  <script data-inline-file-name='utilitybarbase.min.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/utilitybarbase.min.js */ var utilitybarBase=function(e){return 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as a Method * define function as object methods * @type {Object} */ window.digitalData = { user: {}, page: {}, merchandising: {}, getQueryParam : function (param) { var index, key, value, hash; var hashes = window.location.href.slice(window.location.href.indexOf('?') + 1).split('&'); for (index = 0; index < hashes.length; index++) { hash = hashes[index].split('='); key = hash[0]; value = hash[1]; if (key.toUpperCase() === param.toUpperCase()) return value; } return ''; }, getValOnce: function (value, cookieName, expiry, timeUnit) { var currentDate = new Date; var currentCookieValue; // timeUnit of 'm' is minutes represented in milliseconds // thus 86400000 = 24 hours = 1 day var interval = timeUnit == 'm' ? 60000 : 86400000; cookieName = cookieName ? cookieName : 'digitaldata_gvo'; value = value ? value : ''; expiry = expiry ? expiry : 0; currentCookieValue = this.getCookie(cookieName); if (value) { currentDate.setTime(currentDate.getTime() + expiry * interval); this.setCookie(cookieName, value, expiry == 0 ? 0 : currentDate); } return value == currentCookieValue ? '' : value; }, getCookie: function (key) { var result = ""; var cookies = document.cookie ? document.cookie.split('; ') : []; for (var i = 0; i < cookies.length; i++) { var parts = cookies[i].split('='); var name = decodeURIComponent(parts.shift()); var cookie = parts ? parts.join('=') : []; // Prevent storing or parsing of a cookie that we couldn't decode. if (cookie && key === name) { // removes surrounding quotes if (cookie.indexOf('"') === 0) { // This is a quoted cookie as according to RFC2068, unescape... cookie = cookie.slice(1, -1).replace(/\\"/g, '"').replace(/\\\\/g, '\\'); } // parse utf8 characters try { cookie = decodeURIComponent(cookie); } catch (e) {} result = cookie; // we found it, don't bother looking at other cookies break; } } return result; }, setCookie : function(name, value, numDays){ if ( !numDays ) numDays = 31; var expires = new Date(); expires.setTime(expires.getTime() + (1000 * 60 * 60 * 24 * numDays)); document.cookie = name+ '=' + escape(value) + '; path=/; expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }, /** * get the master domain based on business rules */ getMasterDomain : function () { // default the master domain var masterDomain = 'thermofisher.com'; // check for alternate domain portion of URL var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }, /** * Check if init has been initiated once * @type {Boolean} */ initted: false, /** * @return {Array} method returns an array of a given object's key properties */ init: function () { this.page.country = this.getCookie("CK_ISO_CODE") || 'us'; this.page.language = this.getCookie('CK_LANG_CODE') || 'en'; this.page.siteName = 'thermo'; //hard coded this.initMerchandisingData(); this.initUserData(); this.displayDigitalData(); this.formSubmitEvent(); }, //specific function to set type of the page // need specific function to keep page type separate from other page attributes setPageType: function (type) { this.setPageAttribute('type', type); }, // generic function to set page attributes setPageAttribute: function (key, value) { this.page[key] = value; }, // display digitalData object displayDigitalData: function () { }, // specific function to add an object to digitalData addDigitDataObject: function (key, object) { this[key] = object; }, addChildObjectAttribute: function(child, key, value){ this[child][key] = value; }, initUserData: function(){ var gigyaCookie = this.getCookie("identity_uid"); this.user.gigyaId = ""; this.user.loginStatus = "anonymous"; if( gigyaCookie != ""){ this.user.gigyaId = gigyaCookie; this.user.loginStatus = "logged in"; } }, /** * Check if init has been initiated once * @type {Boolean} */ merchandisingDataInitted: false, initMerchandisingData: function () { // read cid and icid value from session cookie this.merchandising.icid = this.getCookie('s_ev21_tc'); this.merchandising.cid = this.getCookie('s_cmp_tc'); // EMID value this.merchandising.emid = this.getQueryParam("emid"); // referrer by domain if (typeof document.referrer !== 'undefined' && document.referrer.length > 0) { var masterDomain = this.getMasterDomain(); var refReg = document.referrer; var referrerDomain = refReg.match(/:\/\/([^/]+)\//); if (referrerDomain !== null && referrerDomain[1].indexOf(masterDomain) == -1) { this.merchandising.referrer = referrerDomain; } } document.addEventListener('registerMerchandisingData', function (event) { for (var key in event.detail) { console.log("Listener data copied", key, event.detail[key] ); digitalData.merchandising[key] = event.detail[key]; } // Map some analytics attributes to merchandising session attributes digitalData.merchandising.sessionId = digitalData.merchandising.analyticsVisitorID; digitalData.merchandising.s_vi_low = digitalData.merchandising.analyticsVisitorIDLow; digitalData.merchandising.s_vi_high = digitalData.merchandising.analyticsVisitorIDHigh; console.log("digitalData: Captured registerMerchandisingData event"); digitalData.merchandisingDataInitted = true; // Call emailCampaignRecord if the digitalDataAnalyticsListener object is loaded if (typeof digitalDataAnalyticsListener != "undefined") { console.log("digitalData: Calling email campaign record"); digitalDataAnalyticsListener.emailCampaignRecord(); } }); }, formSubmitEvent: function () { var formId = this.getQueryParam("form-submit-id"); if ((formId) && formId !== "" && formId !== null) { var eventDetail = { detail: { form: { id: formId } } }; var formSubmitEvent = new CustomEvent('formSubmit', eventDetail); console.log('form submit event started'); document.dispatchEvent(formSubmitEvent); console.log('form submit event fired', eventDetail); //flush grepToken from Session Storage sessionStorage.removeItem('grepTokenSO'); } }, modalVideoEvent: function (videoId) { if (((videoId) && videoId !== "" && videoId !== null)) { var eventDetail = { detail: { video: { playerId: videoId } } }; var modalVideoEvent = new CustomEvent('videoPlayerLoaded', eventDetail); document.dispatchEvent(modalVideoEvent); } }, customClickEvent: function (clickDetail) { if (((clickDetail) && clickDetail !== "" && clickDetail !== null)) { var eventDetail = { detail: { CustomLink: { linkName: clickDetail } } } var customClickEvent = new CustomEvent('customLinkClicks', eventDetail); document.dispatchEvent(customClickEvent); } } } })(); window.digitalData.init(); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_25"); </script> <script type="text/javascript"> var localizedStrings = { "ACCEPTANCE": "Acceptance of Terms of Use", "BTN_AGREE": "Agree", "BTN_DISAGREE": "Disagree", "PROCESSING_MESSAGE" :"processing ... please wait ...", "ADD_TO_CART_QUANTITY_ERROR":"You must provide a quantity to add an item to the cart", "ADD_TO_CART_VALID_QUANTITY_ERROR":"You must provide a valid quantity to add an item to the cart", "VIEW_CART" :"View cart & checkout", "VIEW_CONTACT_DETAIL" :"View Contact Details", "ADD_TO_CART_NOTIFICATION":"Add to Cart Notification", "UPDATE_CART" :"Update Cart", "PRINCIPAL_INVESTIGATOR":"Principal Investigator", "PRINCIPAL_INVESTIGATOR_TEAM_LEADER":"Principal Investigator or Team Leader", "PRINCIPAL_INVESTIGATOR_CHIEF":"Principal Investigator or Chief", "EMAIL_ERROR_1" :"Please Provide Collegues Email", "EMAIL_ERROR_2" :"Please enter a valid colleague email address", "EMAIL_ERROR_3" :"Please Provide Your Email", "EMAIL_ERROR_4" :"Please enter a valid email address", "ERROR_OCCURED_MESSAGE" :"The following errors occured", "NEXT" :"Next", "PREVIOUS" :"Prev", "IMAGE" :"Image", "SAVE_TO_LIST_ERROR_1" :"Please enter a list name.", "SAVE_TO_LIST_ERROR_2" :"Please enter a different list name that does not include the following: ?,/,\\,%,^,!", "MINICART_ERROR_1" :"Unable to connect to eCommerce system. 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Please try again later.", "MINICART_MESSAGE_1" :"Adding item(s) to cart...", "MINICART_MESSAGE_2" :"Removing item(s) from cart...", "MINICART_CART_NAME_LABEL_1" :"Recently added to the", "MINICART_NOTE_1" : "Your total price and product details can be viewed in the cart.", MINICART_SUMMARY : "Cart summary", MINICART_PRICE : "Price", MINICART_PRODUCT : "Product", LIST_PRICE : "Price", YOUR_PRICE : "Your price", WEB_PRICE: "Online offer", PRICE_ENDS: "ends", SIGN_IN: "Sign in", //New mini cart CATALOG_NUMBER: "Catalog number:", CONTACT_US: "Contact us", RFQ: "Request quote", LEARN_WHERE_TO_BUY: "Learn where to buy", CURRENCY: "USD", //End new mini cart "CHANGE_CART" :"Change cart", "VIEW_ALL" :"View All", "ITEM" :"item", "ITEMS" :"items", "CLOSE" :"Close", "SUBTOTAL" :"Subtotal", "TOTAL" :"Total", "MANAGE_CART" :"Manage Cart", "FIELD" :"field", "GLOBAL_ERROR_1" :"Please choose one or both of the options for", "GLOBAL_ERROR_2" :"is not a valid e-mail address.", "GLOBAL_ERROR_3" :"Unsupported character(s) were found in field", "GLOBAL_ERROR_4" :"and will be replaced with plain text equivalents (where available). Please review the changes and try again.", "GLOBAL_ERROR_5" :"Please fill in the", "GLOBAL_ERROR_6" :"Quantities must be whole numbers greater than or equal to zero.", "GLOBAL_ERROR_7" :"is either not a number or a number less than zero, please provide a numerical quantity", "GLOBAL_ERROR_8" :"Reserved character | not allowed. Please remove and try again.", "required" : "One or more required fields are missing", "requireOneOfMany" : "At least one field in the group must be filled out", "password" : "Password does not conform to the password policy", "passwordConfirm" : "Password and Confirm Password do not match", "emailConfirm" : "Email and Confirm Email do not match", "secretConfirm" : "Secret Answer and Confirm Secret Answer do not match", "alphanumeric" : "Value must be alphanumeric", "phone" : "Phone number or Fax number provided were non-numeric values", "email" : "Email address provided is in an invalid format", "date" : "Date is in an invalid format (ex. 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var localizedLink = { "B2B_CHECK_OUT_LINK":"/en/US/procurement/lt?cmd=ViewCart&ShoppingCartKey=", "B2B_MANAGE_CART_LINK":"/en/US/procurement/lt?cmd=OILDataDisplay&ShoppingCartKey=", "B2B_VIEW_ALL_LINK":"/en/US/procurement/lt?cmd=ViewCart&ShoppingCartKey=", "LIGGED_IN_CHECKOUT_LINK":"/en/US/direct/lt?cmd=ViewCart&ShoppingCartKey=", "LOGGED_IN_MANAGE_CART_LINK":"/en/US/direct/lt?cmd=OILDataDisplay&ShoppingCartKey=", "LOGGED_IN_VIEW_ALL_LINK":"/en/US/direct/lt?cmd=ViewCart&ShoppingCartKey=", "ANONYMOUS_CHECKOUT_LINK":"/en/US/adirect/lt?cmd=ViewCart&ShoppingCartKey=", "ANONYMOUS_MANAGE_CART_LINK":"/en/US/adirect/lt?cmd=OILDataDisplay&ShoppingCartKey=", "ANONYMOUS_VIEW_ALL_LINK":"/en/US/adirect/lt?cmd=ViewCart&ShoppingCartKey=", "PRODUCT_DETAIL_URL_B2B":"/en/US/procurement/lt?cmd=catProductDetail&productID=", "PRODUCT_DETAIL_URL_ANONYMOUS":"/en/US/adirect/lt?cmd=catProductDetail&productID=", "PRODUCT_DETAIL_URL_LOGGED_IN":"/en/US/direct/lt?cmd=catProductDetail&productID=", "MY_ACCOUNT_LINK_CSR":"/en/US/enterpriseMgr/lt?cmd=HomeDataDisplay", "QUICK_ORDER_ANONYMOUS":"/en/US/adirect/lt?cmd=IVGNQuickOrderLanding", "MY_ACCOUNT_LINK_B2B":"/en/US/procurement/lt?cmd=PartnerSysUserMyAccount", "ORDER_STATUS_LINK_B2B":"/en/US/procurement/lt?cmd=WorkspaceDataDisplay&_Tab=Ordered", "MY_ACCOUNT_LINK":"/en/US/direct/lt?cmd=PartnerSysUserMyAccount", "ORDER_STATUS_LINK":"/en/US/direct/lt?cmd=WorkspaceDataDisplay&_Tab=Ordered", "COMERGENT_CLOSE_SESSION_LINK":"/en/US/procurement/lt?cmd=PunchInOrder&mode=Cancel", "REGISTRATION_URL":"/en/US/adirect/lt?cmd=FullRegistrationData&GroupKey=103&Command=updateExecute&anonymousHomePageMsg=OnlineOrderingPageDisplay", "LIGGED_IN_CHECKOUT_LINK_SCMS":"/en/US/direct/lt?cmd=ViewCart&ShoppingCartKey=", "SCMS_CHECKOUT_SC":"/en/US/procurement/lt?cmd=SetSCMSAddress", "SCMS_CHECKOUT":"/en/US/procurement/lt?cmd=ViewCart&ShoppingCartKey=", "PSCMS_CHECKOUT_SC":"/en/US/procurement/lt?cmd=PSCMSCheckout", "GUEST_USER_AUTH_REDIRECT":"/en/US/procurement/lt?cmd=B2BMasterUserRegistration&operation=identifyUser", "GUEST_USER_AJAX_AUTH":"/en/US/procurement/lt?cmd=B2BMasterUserRegistration&operation=validateNLogin", "GUEST_USER_AJAX_AUTH_UNIQUE_EXPRESS":"/en/US/procurement/lt?cmd=ExpressUniqueUserEmailUpdate", "GUEST_USER_SEARCH_TOOL":"/en/US/direct/lt?cmd=WorkspaceDataDisplay&_Tab=Ordered" }; 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Or, you can <a href="#" class="link_search_tool">use the search tool</a> to look for individual orders.</p>', html:true, trigger:'manual', template: '<div class="popover" style="width: 300px; max-width: none;"><div class="arrow"></div><div class="popover-inner"><h3 class="popover-title"></h3><div class="popover-content"><p></p></div></div></div>' }; </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_26"); </script>   <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("globalHeader:renderEnd"); </script> <div class="full-bg" id="full-bg"></div> <div class="search-bg" id="search-bg"></div> </div> </header> <div id="modal"></div> <div id="root"><div class="pdp-main"><div class="pdp-header"><div class="pdp-header__breadcrumbs-element-structure-container"><div class="pdp-breadcrumbs"><div><core-breadcrumb><core-breadcrumb-item url="/" text="Home" 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class="short-description">Speed up and enhance continuous processing in pharmaceutical research, development or production with the Pharma 24 Twin-Screw Extruder.</div></div><div class="pdp-promos"></div><div class="pdp-product-selector"><div class="pdp-product-selector__icons-options-container"><div class="pdp-product-selector__contact-us-popup"><span class="pdp-product-selector__contact-us-text">Have Questions?</span><div class="pdp-contact-us"></div></div><div class="pdp-product-selector__icons"><span class="pdp-product-selector__text">Change view</span><core-segmentedbuttons><core-segmentedbuttons-item nopadding="true" selected="false" slot="segment"><img slot="content" 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class="pdp-table-product-selector__catalog-number">553-2037</span></td><td>Pharma 24 Twin-Screw Extruder - TSG Application Set</td></tr><tr class=""><td class=""><span class="pdp-table-product-selector__catalog-number">553-2039</span></td><td>Pharma 24 Extruder processes pharmaceutical formulations at feed rates up to 20 kg/h (HME) and 70 kg/h (TSG)</td></tr></tbody></table></div><div class="pdp-options" style="bottom:0px;width:100%;visibility:hidden"> 3 Options </div></div></div></div><div class="pdp-commerce-box col-lg-3 col-md-12"><div class="commerce-box-inner"><div class="pdp-card"><div class="pdp-commerce-box-content" slot="content"><div class="pdp-commerce-box--first-row"><span class="pdp-commerce-box--first-row--catalog-number-wrapper"><span class="pdp-commerce-box--catalog-number">Catalog number </span><span class="pdp-commerce-box--catalog-number-value">553-2038</span></span><div data-testid="favorites-component"><span data-testid="favorites-icon" 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Select to save this product to a list." alignment="end" placement="bottom"><span class="icon-24-rating-mono"></span></core-tooltip></span></div></div><div class="pdp-divider"></div><div class="pdp-price"><span class="pdp-price__price-label">Price (SGD)</span><span class="pdp-price__productSize">/ Each</span><div> - </div><core-button type="button" variant="primary" fullspace="true" size="medium"><span slot="content">Request A Quote</span></core-button></div><div class="pdp-divider"></div><div class="pdp-ordering-attributes"><div class="pdp-ordering-attribute"><div class="pdp-ordering-attribute__label">Description:</div><div class="pdp-ordering-attribute__value">Pharma 24 Twin-Screw Extruder - HME Application Set</div></div></div></div></div><div class="pdp-recurring-order"></div><div class="pdp-custom-forms"></div></div></div></div></div><div class="pdp-details"><div class="pdp-nav" style="top:0px"><core-navigationbar variant="horizontal"><core-navigationbar-item slot="nav-item" selected="true" variant="horizontal" label="Product Overview" href="/" target="_top"></core-navigationbar-item><core-navigationbar-item slot="nav-item" selected="false" variant="horizontal" label="Documents" href="/" target="_top"></core-navigationbar-item></core-navigationbar></div><div class="pdp-nav-containers"><div class="pdp-nav-container pdp-product-overview row" id="productOverview"><div class="pdp-product-description col-md-12 col-lg-7 "><div class="pdp-product-description-inner" id="product-description">The Thermo Scientific™ Pharma 24 Twin-Screw Extruder, with avaialble HME and Twin-Screw Granulation (TSG) Application Sets, is ideal for continuous processing in research, development or production in the pharmaceutical industry. The Pharma 24 extruder drives reduced clean room area, consistent and controllable processing, reduced product changeover time, on-demand production, minimized scale-up risk and reliable cleaning. It is suitable for process analytical technology (PAT).</div><div class="pdp-product-description-inner">The Pharma 24 Twin-Screw Extruder features: <ul> <li>A small footprint to take up less space in clean rooms</li> <li>Continuous operation which consumes fewer utilities than traditional batch processes</li> <li>High free volume screw design</li> <li>A small process inventory</li> <li>Lower ingredient consumption which reduces handling and operator exposure</li> <li>Segmented screws and barrel</li> <li>Removable screws and liners</li> </ul> <b>PAT Compatibility:</b> PAT can be applied to your process to monitor parts of theprocess such as homogeneity of mixing or moisture content to assure required product quality. The Pharma 24 Extruder can be used with a range of PAT instruments such as Thermo Scientific™ FT-NIR system. <br /><br /> <b>Options:</b> We offer a full range of GMP compliant ancillaries which are matched to the extruder performance. This downstream equipment can be integrated into the extruder control system.<br /><br /> <b>For TSG configurations:</b> available ancillaries include volumetric or gravimetric dosing feeders and liquid injection pumps.<br /><br /> In addition, self-contained units of either configuration can be operated with recirculating chillers to reduce water consumption.<br /><br /> TSG configuration recommended for: <ul> <li>Wet granulation</li><li>Dry/melt granulation</li></ul> <b>For HME configurations</b>: available ancillaries include volumetric or gravimetric dosing feeders, air cooled conveyors for product cooling, strand and face-cut pelletizers to make pellets, or chill roll/flaker units for rapid product cooling and flaking. <br /><br /> HME configuration recommended for: <ul> <li>Solubility enhancement</li> <li>Modified release</li> <li>Co-extrusion</li> <li>Drug delivery systems</li> <li>Biomedical products</li> </ul></div></div><div class="col-lg-5 col-md-12"><div class="pdp-specifications"><div class="pdp-card pdp-specifications-card nopadding"><div class="pdp-specifications__wrapper" slot="content"><div class="pdp-specifications__title"><span class="pdp-specifications__text">Specifications</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Interface</span><span class="pdp-specification-row__value">Touch screen control panel, Siemens PLC, Standard HMI languages: German and English (optional languages on request), 21 CFR part 11 compliance, Four different user levels with predefined access rights</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Power Connections</span><span class="pdp-specification-row__value">400 V 3PH+N+PE, 50/60 Hz</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Power Consumption</span><span class="pdp-specification-row__value">50 A</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Max. Torque</span><span class="pdp-specification-row__value">52.5 Nm/Screw</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Barrel Bore Diameter</span><span class="pdp-specification-row__value">24 mm</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Dimensions (L x W x H)</span><span class="pdp-specification-row__value">2075 x 875 x 1630 mm</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Description</span><span class="pdp-specification-row__value">Pharma 24 Twin-Screw Extruder - HME Application Set</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Extruder Design</span><span class="pdp-specification-row__value">Barrel designed with removable top and bottom liners made from pharma grade steel, horizontally split, with top half lifting upward. Main feed port (cooled) plus 7 multi-purpose top feed/vent/injection ports</span></div><div class="pdp-specification-row"><span class="pdp-specification-row__name">Unit Size</span><span class="pdp-specification-row__value">Each</span></div></div></div></div><div class="offers-wrapper"></div></div></div></div></div></div></div> <script src="/store/v3/products/static/main.cc5dd2ca25cc5de0116b.js" async></script> <style> .no-logo{ min-height: 80px; } </style> <script> window.showGlobalFooter = function() { var footer = document.getElementById("tf-global-footer"); if (footer) { footer.style.display = 'block'; } } </script> <footer id="tf-global-footer" style="display: none;"> <div class="globalFooter" data-orig="tfpt-header-footer" data-app-env="prod" data-site="tf" data-hostname="www.thermofisher.com" data-x-host="www.thermofisher.com" data-env="prod" data-hash="468bd07150dbbf" data-version="4.03.29" data-analytics-section="header" data-aem-syndication-info="(sg:en-sg:anonymous:https-tf)" 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