Congresses & Publications

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It is not intended to serve as a comprehensive list of all congress and publications resources.</p><p>If you would like to discover more educational content, please use the “<a href="/search" data-entity-type="node" data-entity-uuid="9f486a97-df17-4aa0-a594-f7e1b0f74c35" data-entity-substitution="canonical"><strong>Search</strong></a>” feature.</p></div> </div> </div> <div class="bundle-general-text-section field__item"> <div class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--solar"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><blockquote><p>The material below is provided to support scientific exchange. Any content about investigational therapeutics or investigational uses of FDA-approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of FDA approval.</p><p>Alnylam does not recommend or suggest use of its products in any manner inconsistent with the approved Prescribing Information.</p></blockquote></div> </div> </div> <div class="bundle-accordion field__item"> <div class="paragraph paragraph--type--accordion paragraph--view-mode--default accordion-wrapper"> <div class="expand-wrapper"> <a href="#" class="expand-all" role="button">Expand All</a> <a href="#" class="collapse-all" style="display:none;" role="button">Collapse All</a> </div> <div class="accordion"> <div class="paragraph paragraph--type--accordion-section paragraph--view-mode--default accordion-item"> <div id="AHP"> <p class="accordion-header" id="panelsStayOpen-headingOne-534"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#panelsStayOpen-collapseOne-534" aria-expanded="false" aria-controls="panelsStayOpen-collapseOne"> <div class="clearfix text-formatted field field--name-field-heading field--type-text-long field--label-hidden field__item"><h2>Acute hepatic porphyria (AHP)</h2></div> </button> </p> </div> <div id="panelsStayOpen-collapseOne-534" class="accordion-collapse collapse" aria-labelledby="panelsStayOpen-headingOne-534"> <div class="accordion-body"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-tabs field__item"> <div class="paragraph paragraph--type--tabs paragraph--view-mode--default accordion-tabs" role="tablist"> <div class="two-tabs"> <div class="tab-wrapper"> <input checked type="radio" id="tab-530" name="tab-group-533" role="tab" aria-controls="content-530" tabindex="0" > <label for="tab-530" role="tab" tabindex="0" aria-selected="true" aria-controls="content-530" > Congress Resources </label> </div> <div class="tab-wrapper"> <input type="radio" id="tab-532" name="tab-group-533" role="tab" aria-controls="content-532" tabindex="0" > <label for="tab-532" role="tab" tabindex="0" aria-selected="false" aria-controls="content-532" > Publications </label> </div> </div> <div class="tab-content visible" id="content-530" role="tabpanel" aria-labelledby="tab-530" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-card-grid field__item"> <div class="paragraph paragraph--type--card-grid paragraph--view-mode--default tabs" role="tablist"> <div class="field__item"> <a href=/congresses-publications/american-association-study-liver-diseases-aasld-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AASLD 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>San Diego, CA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 15-19, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/international-congress-porphyrins-porphyrias-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ICPP 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Pamplona, Spain</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>September 21-25, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-association-study-liver-easl-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>EASL 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Milan, Italy</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>June 5-8, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-association-study-liver-diseases-aasld-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AASLD 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Boston, MA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 10-14, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/international-porphyrias-symposium-ips-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>IPS 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Bethesda, MD, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>October 26-29, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-association-study-liver-easl-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>EASL 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Vienna, Austria</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>June 21-24, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/academy-managed-care-pharmacy-amcp-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AMCP 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>San Antonio, TX, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>March 21-24, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/hemostasis-and-thrombosis-research-society-htrs-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>HTRS 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Orlando, FL, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>March 10-12, 2023</p></div> </div> </div> </div> </a> </div> </div> </div> </div> </div> </div> <div class="tab-content hidden" id="content-532" role="tabpanel" aria-labelledby="tab-532" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=780> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/153" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1186/s13023-024-03284-w" target="_blank" class="information-link"> Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>October 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Orphanet Journal of Rare Diseases</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Eliane Sardh, Manisha Balwani, David C Rees, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=771> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/150" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1111/liv.16037" target="_blank" class="information-link"> High disease burden and healthcare resource usage in patients with acute porphyria—A population-based analysis </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>October 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Liver International</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Ulrich Stölzel, Bjoern Ambrosius, Brun S, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1016/j.jfma.2023.10.016 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>A randomized, placebo-controlled study of givosiran in patients with acute hepatic porphyrias (ENVISION): Final (36-month) analysis of the Taiwan Cohort</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>June 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Journal of the Formosan Medical Association</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Ming-Jen Lee, Hung-Chou Kuo, Lin-Na Chou, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1002/jmd2.12416 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Elevated homocysteine is negatively correlated with plasma cystathionine β ‐synthase activity in givosiran‐treated patients</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>March 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Journal of Inherited Metabolic Disease</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Mark A. Keibler, Gautham V. Sridharan, Marianne T. Sweetser, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1186/s13023-023-02913-0 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Clinical features of acute attacks, chronic symptoms, and long-term complications among patients with acute hepatic porphyria in Japan: a real-world claims database study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>December 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Orphanet Journal of Rare Diseases</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Yutaka Horie, Yuka Yasuoka & Tomohide Adachi</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1002/jmd2.12343 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Quantifying the Impact of Acute Hepatic Porphyria on Well-Being via Patient-Reported Outcomes: Results from the Porphyria Worldwide Patient Experience Research (POWER) Study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>October 2022</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>JIMD Reports</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Amy Dickey, Kristen Wheeden, Desiree Lyon, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--accordion-section paragraph--view-mode--default accordion-item"> <div id="ATTR"> <p class="accordion-header" id="panelsStayOpen-headingOne-84"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#panelsStayOpen-collapseOne-84" aria-expanded="false" aria-controls="panelsStayOpen-collapseOne"> <div class="clearfix text-formatted field field--name-field-heading field--type-text-long field--label-hidden field__item"><h2>Transthyretin (ATTR) amyloidosis</h2></div> </button> </p> </div> <div id="panelsStayOpen-collapseOne-84" class="accordion-collapse collapse" aria-labelledby="panelsStayOpen-headingOne-84"> <div class="accordion-body"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-tabs field__item"> <div class="paragraph paragraph--type--tabs paragraph--view-mode--default accordion-tabs" role="tablist"> <div class="two-tabs"> <div class="tab-wrapper"> <input checked type="radio" id="tab-81" name="tab-group-83" role="tab" aria-controls="content-81" tabindex="0" > <label for="tab-81" role="tab" tabindex="0" aria-selected="true" aria-controls="content-81" > Congress Resources </label> </div> <div class="tab-wrapper"> <input type="radio" id="tab-82" name="tab-group-83" role="tab" aria-controls="content-82" tabindex="0" > <label for="tab-82" role="tab" tabindex="0" aria-selected="false" aria-controls="content-82" > Publications </label> </div> </div> <div class="tab-content visible" id="content-81" role="tabpanel" aria-labelledby="tab-81" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-card-grid field__item"> <div class="paragraph paragraph--type--card-grid paragraph--view-mode--default tabs" role="tablist"> <div class="field__item"> <a href=/congresses-publications/ISPOR-EU-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ISPOR Europe 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Barcelona, Spain</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 17-20, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-heart-association-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AHA 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Chicago, IL, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 16-18, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-association-neuromuscular-electrodiagnostic-medicine-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AANEM 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Savannah, GA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>October 15-18, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/heart-failure-society-america-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>HFSA 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Atlanta, GA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>September 27-30, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-society-cardiology-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ESC 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>London, United Kingdom</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>August 30 - September 2, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/peripheral-nerve-society-pns-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>PNS 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Montréal, Quebec, Canada</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>June 22–25, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/international-society-amyloidosis-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ISA 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Rochester, MN, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 26–30, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-college-cardiology-2024-ttr> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ACC 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Atlanta, GA, USA </p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>April 6–8, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/aahs-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AAHS 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Nassau, Bahamas</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>January 9–13, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-heart-association-2023-ttr> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AHA 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Philadelphia, PA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 11–13, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-attr-amyloidosis-meeting-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>EU-ATTR 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Madrid, Spain</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 2–3, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/heart-failure-society-america-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>HFSA 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Cleveland, OH, USA </p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>October 6–9, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-society-cardiology-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ESC 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Amsterdam, Netherlands</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>August 25–28, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/peripheral-nerve-society-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>PNS 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Copenhagen, Denmark</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>June 17–20, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/italian-association-study-peripheral-nervous-system-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ASNP 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Naples, Italy</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 25–27, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-federation-national-associations-orthopaedics-and-traumatology-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>EFORT 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Vienna, Austria</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 24–26, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-society-cardiology-heart-failure-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ESC-HF 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Prague, Czechia</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 20–23, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-academy-neurology-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AAN 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Boston, MA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>April 22–27, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-college-cardiology-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ACC 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>New Orleans, LA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>March 4–6, 2023</p></div> </div> </div> </div> </a> </div> </div> </div> </div> </div> </div> <div class="tab-content hidden" id="content-82" role="tabpanel" aria-labelledby="tab-82" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=781> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/155" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1016/j.jacc.2024.11.015" target="_blank" class="information-link"> Outpatient Worsening Heart Failure in Patients with Transthyretin Amyloidosis with Cardiomyopathy in the HELIOS-B Trial </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>November 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Journal of the American College of Cardiology</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Marianna Fontana, Mathew S. Maurer, Julian D. Gillmore, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=782> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/154" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1186/s13023-024-03407-3" target="_blank" class="information-link"> The journey to diagnosis of wild-type transthyretin-mediated (ATTRwt) amyloidosis: a path with multisystem involvement </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>November 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Orphanet Journal of Rare Diseases</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Chafic Karam, Colleen Moffit, Catherine Summers, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=772> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/148" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1080/13506129.2024.2409760" target="_blank" class="information-link"> Neurofilament light chain as a biomarker for hereditary ATTR amyloidosis - correlation between neurofilament light chain and nerve conduction study </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>October 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Amyloid</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Masateru Tajiri, Mitsuto Sato, Minori Kodaira, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=2024> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/149" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://www.nejm.org/stoken/default+domain/REPRINTS_36492/full?redirectUri=/doi/full/10.1056/NEJMoa2409134" target="_blank" class="information-link"> Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>August 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>New England Journal of Medicine</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Marianna Fontana, John L. Berk, Julian D. Gillmore, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=783> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/publication/152" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1111/ene.16384" target="_blank" class="information-link"> Effectiveness of patisiran after switching from tafamidis for the treatment of hereditary transthyretin-mediated amyloidosis with polyneuropathy </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2024</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>European Journal of Neurology</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Celine Labeyrie, Madeline Merkel, Sakshi Sethi, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.57264/cer-2023-0158 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Six-minute walk test as clinical end point in cardiomyopathy clinical trials, including ATTR-CM: a systematic literature review</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>June 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Journal of Comparative Effectiveness Research</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Jose Nativi-Nicolau, Ali Yilmaz, Noel Dasgupta, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1016/j.jfma.2024.03.008 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Patisiran, an RNAi therapeutic for hereditary transthyretin-mediated amyloidosis: Sub-analysis in Taiwanese patients from the APOLLO study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>March 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>J Formos Med Assoc</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Lin KP, Yang CC, Lee YC, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1007/s40120-024-00595-9 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Impact of Baseline Neuropathy Severity on Vutrisiran Treatment Response in the Phase 3 HELIOS-A Study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>March 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Neurol Ther</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Marco Luigetti, Dianna Quan, John L. Berk, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1002/ejhf.3138 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Impact of vutrisiran on exploratory cardiac parameters in hereditary transthyretin-mediated amyloidosis with polyneuropathy</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>February 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>European Journal of Heart Failure</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Pablo Garcia-Pavia, Martha Grogan, Parag Kale, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1056/NEJMoa2300757 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>October 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>The New England Journal of Medicine</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Mathew Maurer, Parag Kale, Marianna Fontana,  et al</p> </div> </div> </div> </div> </div> <div class="footer"> <div class="clearfix text-formatted field field--name-field-information-footer field--type-text-long field--label-hidden field__item"><p><em>Alnylam Pharmaceuticals submitted a supplemental New Drug Application (sNDA) to the FDA for patisiran for the treatment of the cardiomyopathy of ATTR amyloidosis based on data from the APOLLO-B study. The FDA subsequently completed their review of the application in 2023 and issued a complete response letter (CRL).</em></p></div> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1007/s40262-023-01292-w class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Pharmacokinetics and Pharmacodynamics of Patisiran in Patients with hATTR Amyloidosis and with Polyneuropathy After Liver Transplantation</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>August 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Clinical Pharmacokinetics</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Prajakta Badri, Bahru Habtemariam, Megan Melch, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1080/13506129.2023.2232520 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Treatment response and neurofilament light chain levels with long-term patisiran in hereditary transthyretin-mediated amyloidosis with polyneuropathy: 24-month results of an open-label extension study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Amyloid</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Simina Ticau, Emre Aldinc, Michael Polydefkis, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1007/s40120-023-00522-4 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Impact of Vutrisiran on Quality of Life and Physical Function in Patients with Hereditary Transthyretin-Mediated Amyloidosis with Polyneuropathy</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Neurology and Therapy</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Laura Obici, Senda Ajroud-Driss, Kon-Ping Lin, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1080/14656566.2023.2215925 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Indirect treatment comparison (ITC) of the efficacy of vutrisiran and tafamidis for hereditary transthyretin-mediated amyloidosis with polyneuropathy</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>May 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Expert Opinion on Pharmacotherapy</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Madeline Merkel, David Danese, Chongshu Chen, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1002/ejhf.2783 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Effect of patisiran on stroke volume in hereditary transthyretin-mediated amyloidosis: insights from pressure–volume analysis of the APOLLO study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>January 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>European Journal of Heart Failure</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Hannah Rosenblum, Jan Griffin, Masatoshi Minamisawa, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.36660/ijcs.20200306 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Gene Silencing Therapeutics in Cardiology: A Review Article</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>September 2022</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>International Journal of Cardiovascular Sciences</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Patrick Jay, Martin Maier, Laura Saltonstall, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1080/13506129.2022.2118043 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Impact of baseline polyneuropathy severity on patisiran treatment outcomes in the APOLLO trial</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>September 2022</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Amyloid</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Dianna Quan, Laura Obici, John Ber, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1080/13506129.2022.2091985 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Efficacy and safety of vutrisiran for patients with hereditary transthyretin-mediated amyloidosis with<br>polyneuropathy: a randomized clinical trial</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2022</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Amyloid</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>David Adams, Ivailo Tournev, Mark Taylor, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1111/ajt.17009 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Patisiran treatment in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy after liver transplantation</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>June 2022</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>American Journal of Transplantation</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Hartmut Schmidt, Jonas Wixner, Violaine Planté-Bordeneuve, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1161/circgen.121.003466 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Presence of the V122I Variant of Hereditary Transthyretin-Mediated Amyloidosis Among Self-Reported White Individuals in a Sponsored Genetic Testing Program</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p dir="ltr">Aug 31, 2021</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p dir="ltr"><em>Circ Genom Precis Med</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p dir="ltr">Trachtenberg BH, Shah SK, Nussbaum RL, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1016/S1474-4422(20)30368-9 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>November 2020</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>The Lancet Neurology</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>David Adams, Michael Polydefkis, Alejandra González-Duarte, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1080/13506129.2020.1830272 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">DISCOVERY: prevalence of transthyretin (TTR) mutations in a US-centric patient population suspected of having cardiac amyloidosis</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>Oct 12, 2020</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Amyloid</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p dir="ltr">Roteta Unceta Barrenechea A, Lahuerta Pueyo C, Melero Polo J, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-publication field__item"> <div class="paragraph paragraph--type--publication paragraph--view-mode--default publication" id=484> <div class="field field--name-field-publication field--type-entity-reference field--label-hidden field__item"> <article about="/node/86" class="node node--type-publication node--view-mode-module information"> <div class="text"> <a href="https://doi.org/10.1080/13506129.2020.1758658" target="_blank" class="information-link"> Transthyretin-stabilising mutation T119M is not associated with protection against vascular disease or death in the UK Biobank </a> </div> <div class="information-lines"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>September 2020</p> </div> </div> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Amyloid</em></p> </div> </div> <div class="information-line last"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Margaret M Parker, Simina Ticau, James Butler, et al</p> </div> </div> </div> </article> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1002/jcph.1480 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure-Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin-Mediated (hATTR) Amyloidosis</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2019</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>The Journal of Clinical Pharmacology</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Xiaoping Zhang, Varun Goel, Husain Attarwala, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1001/jamacardio.2019.0849 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial<br>Strain in Hereditary Transthyretin Amyloidosis: The APOLLO Study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>March 2019</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Jama Cardiology</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Masatoshi Minamisawa, Brian Claggett, David Adams, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1161/CIRCULATIONAHA.118.035831 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Effects of Patisiran, an RNA Interference Therapeutic, on Cardiac Parameters in Patients with Hereditary Transthyretin-Mediated Amyloidosis: An Analysis of the APOLLO study</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>January 2019</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Circulation </em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Scott Solomon, David Adams, Arnt Kristen, et al <br> </p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1056/NEJMoa1716153 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2018</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>The New England Journal of Medicine</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>David Adams, Alejandra Gonzalez-Duarte, William O’Riordan, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--accordion-section paragraph--view-mode--default accordion-item"> <div id="CV"> <p class="accordion-header" id="panelsStayOpen-headingOne-88"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#panelsStayOpen-collapseOne-88" aria-expanded="false" aria-controls="panelsStayOpen-collapseOne"> <div class="clearfix text-formatted field field--name-field-heading field--type-text-long field--label-hidden field__item"><h2>Cardiovascular (CV)</h2></div> </button> </p> </div> <div id="panelsStayOpen-collapseOne-88" class="accordion-collapse collapse" aria-labelledby="panelsStayOpen-headingOne-88"> <div class="accordion-body"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-tabs field__item"> <div class="paragraph paragraph--type--tabs paragraph--view-mode--default accordion-tabs" role="tablist"> <div class="two-tabs"> <div class="tab-wrapper"> <input checked type="radio" id="tab-85" name="tab-group-87" role="tab" aria-controls="content-85" tabindex="0" > <label for="tab-85" role="tab" tabindex="0" aria-selected="true" aria-controls="content-85" > Congress Resources </label> </div> <div class="tab-wrapper"> <input type="radio" id="tab-86" name="tab-group-87" role="tab" aria-controls="content-86" tabindex="0" > <label for="tab-86" role="tab" tabindex="0" aria-selected="false" aria-controls="content-86" > Publications </label> </div> </div> <div class="tab-content visible" id="content-85" role="tabpanel" aria-labelledby="tab-85" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-card-grid field__item"> <div class="paragraph paragraph--type--card-grid paragraph--view-mode--default tabs" role="tablist"> <div class="field__item"> <a href=/congresses-publications/american-heart-association-2024-cv> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AHA 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Chicago, IL, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 16-18, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-society-cardiology-2024-htn> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ESC 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>London, United Kingdom</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>August 30 - September 2, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-society-hypertension-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ESH 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Berlin, Germany</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 31–June 3, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-college-cardiology-2024-htn> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ACC 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Atlanta, GA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>April 6–8, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-heart-association-2023-htn> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>AHA 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Philadelphia, PA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 11–13, 2023</p></div> </div> </div> </div> </a> </div> </div> </div> </div> </div> </div> <div class="tab-content hidden" id="content-86" role="tabpanel" aria-labelledby="tab-86" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1001/jama.2024.0728 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">RNA Interference With Zilebesiran for Mild to Moderate Hypertension: The KARDIA-1 Randomized Clinical Trial</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>February 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p>JAMA</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>George L Bakris, Manish Saxena, Anil Gupta, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1056/NEJMoa2208391 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Zilebesiran, an RNA interference therapeutic agent for hypertension</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>July 2023</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p>NEJM</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Akshay Desai, David Webb, Jorg Taubel, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1161/HYPERTENSIONAHA.120.16876 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Renoprotective effects of small interfering RNA targeting liver angiotensinogen in experimental chronic kidney disease</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>March 2021</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p>Hypertension</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Dominique Bovée, Liwei Ren, Estrellita Uijl, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1042/CS20201239 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>January 2021</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p>Clinical Science</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Estrellita Uijl, Liwei Ren, Katrina Mirabito Colafella, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1172/JCI99417 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>April 2020</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p>The Journal of Clinical Investigation</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Nadine Haase, Donald Foster, Mark Cunningham, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1161/HYPERTENSIONAHA.119.12703 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p dir="ltr">Strong and sustained antihypertensive effect of small interfering RNA targeting liver angiotensinogen</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>April 2019</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p>Hypertension</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Estrellita Uijl, Katrina Mirabito Colafella, Yuan Sun, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--accordion-section paragraph--view-mode--default accordion-item"> <div id="Metabolic"> <p class="accordion-header" id="panelsStayOpen-headingOne-749"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#panelsStayOpen-collapseOne-749" aria-expanded="false" aria-controls="panelsStayOpen-collapseOne"> <div class="clearfix text-formatted field field--name-field-heading field--type-text-long field--label-hidden field__item"><h2>Metabolic</h2></div> </button> </p> </div> <div id="panelsStayOpen-collapseOne-749" class="accordion-collapse collapse" aria-labelledby="panelsStayOpen-headingOne-749"> <div class="accordion-body"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-tabs field__item"> <div class="paragraph paragraph--type--tabs 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class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--default"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><p>Content coming soon</p></div> </div> </div> </div> </div> </div> <div class="tab-content hidden" id="content-758" role="tabpanel" aria-labelledby="tab-758" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-general-text-section field__item"> <div class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--default"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><p>Content coming soon</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--accordion-section paragraph--view-mode--default accordion-item"> <div id="Neurologic"> <p class="accordion-header" id="panelsStayOpen-headingOne-756"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#panelsStayOpen-collapseOne-756" aria-expanded="false" aria-controls="panelsStayOpen-collapseOne"> <div class="clearfix text-formatted field field--name-field-heading field--type-text-long field--label-hidden field__item"><h2>Neurologic</h2></div> </button> </p> </div> <div id="panelsStayOpen-collapseOne-756" class="accordion-collapse collapse" aria-labelledby="panelsStayOpen-headingOne-756"> <div class="accordion-body"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-tabs field__item"> <div class="paragraph paragraph--type--tabs paragraph--view-mode--default accordion-tabs" role="tablist"> <div class="two-tabs"> <div class="tab-wrapper"> <input checked type="radio" id="tab-754" name="tab-group-755" role="tab" aria-controls="content-754" tabindex="0" > <label for="tab-754" role="tab" tabindex="0" aria-selected="true" aria-controls="content-754" > Congress Resources </label> </div> <div class="tab-wrapper"> <input type="radio" id="tab-760" name="tab-group-755" role="tab" aria-controls="content-760" tabindex="0" > <label for="tab-760" role="tab" tabindex="0" aria-selected="false" aria-controls="content-760" > Publications </label> </div> </div> <div class="tab-content visible" id="content-754" role="tabpanel" aria-labelledby="tab-754" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-card-grid field__item"> <div class="paragraph paragraph--type--card-grid paragraph--view-mode--default tabs" role="tablist"> <div class="field__item"> <a href=/congresses-publications/clinical-trials-on-alzheimers-disease-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>CTAD 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Madrid, Spain</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>October 29 - November 1, 2024</p></div> </div> </div> </div> </a> </div> </div> </div> </div> </div> </div> <div class="tab-content hidden" id="content-760" role="tabpanel" aria-labelledby="tab-760" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-general-text-section field__item"> <div class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--default"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><p>Content coming soon</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--accordion-section paragraph--view-mode--default accordion-item"> <div id="PH1"> <p class="accordion-header" id="panelsStayOpen-headingOne-540"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#panelsStayOpen-collapseOne-540" aria-expanded="false" aria-controls="panelsStayOpen-collapseOne"> <div class="clearfix text-formatted field field--name-field-heading field--type-text-long field--label-hidden field__item"><h2>Primary hyperoxaluria type 1 (PH1)</h2></div> </button> </p> </div> <div id="panelsStayOpen-collapseOne-540" class="accordion-collapse collapse" aria-labelledby="panelsStayOpen-headingOne-540"> <div class="accordion-body"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-tabs field__item"> <div class="paragraph paragraph--type--tabs paragraph--view-mode--default accordion-tabs" role="tablist"> <div class="two-tabs"> <div class="tab-wrapper"> <input checked type="radio" id="tab-536" name="tab-group-539" role="tab" aria-controls="content-536" tabindex="0" > <label for="tab-536" role="tab" tabindex="0" aria-selected="true" aria-controls="content-536" > Congress Resources </label> </div> <div class="tab-wrapper"> <input type="radio" id="tab-538" name="tab-group-539" role="tab" aria-controls="content-538" tabindex="0" > <label for="tab-538" role="tab" tabindex="0" aria-selected="false" aria-controls="content-538" > Publications </label> </div> </div> <div class="tab-content visible" id="content-536" role="tabpanel" aria-labelledby="tab-536" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-card-grid field__item"> <div class="paragraph paragraph--type--card-grid paragraph--view-mode--default tabs" role="tablist"> <div class="field__item"> <a href=/congresses-publications/ph1-american-society-nephrology-asn-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ASN 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>San Diego, CA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>October 24-27, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-renal-association-era-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ERA 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Stockholm, Sweden</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 23-26, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/national-kidney-foundation-nkf-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>NKF 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Long Beach, CA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 14-18, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-society-pediatric-nephrology-aspnpediatric-academic-societies-pas-2024> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ASPN-PAS 2024</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Toronto, Canada</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>May 2-6, 2024</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/ph1-american-society-nephrology-asn-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ASN 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Philadelphia, PA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 11-13, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/american-society-nephrology-asn-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ASN 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Philadelphia, PA, USA</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>November 2-5, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/oxalosis-hyperoxaluria-foundation-ohf-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>OHF 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Perugia, Italy</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>June 23–25, 2023</p></div> </div> </div> </div> </a> </div> <div class="field__item"> <a href=/congresses-publications/european-renal-association-era-2023> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="card-content-wrapper"> <div class="title"> <div class="clearfix text-formatted field field--name-field-title field--type-text-long field--label-hidden field__item"><p>ERA 2023</p></div> <span class="link-icon"><img class="arrow-icon" src="/themes/custom/alnylam/assets/dist/images/arrow.svg" alt="link-icon"/></span> </div> <div class="subtitle"> <div class="clearfix text-formatted field field--name-field-subtitle field--type-text-long field--label-hidden field__item"><p>Milan, Italy</p></div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>June 15-18, 2023</p></div> </div> </div> </div> </a> </div> </div> </div> </div> </div> </div> <div class="tab-content hidden" id="content-538" role="tabpanel" aria-labelledby="tab-538" > <div class="paragraph paragraph--type--tabbed-section paragraph--view-mode--default"> <div class="field field--name-field-accordion-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1016/j.ekir.2024.04.048 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Efficacy and Safety of Lumasiran in Patients With Primary Hyperoxaluria Type 1: Results from a Phase III Clinical Trial</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>April 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Kidney International Reports</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Jeffrey M. Saland, John C. Lieske, Jaap W. Groothoff, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1016/j.jpurol.2023.10.001 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Distinguishing characteristics of pediatric patients with primary hyperoxaluria type 1 in PEDSnet</p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>February 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Journal of Pediatric Urology</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Gregory E. Tasian, Kimberley Dickinson, Grace Park, et al</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> <div class="bundle-information field__item"> <div class="information paragraph paragraph--type--information paragraph--view-mode--default"> <div class="content"> <div class="text"> <a href=https://doi.org/10.1007/s40265-023-01987-1 class="information-link"> <div class="clearfix text-formatted field field--name-field-information-text field--type-text-long field--label-hidden field__item"><p>Lumasiran: A Review in Primary Hyperoxaluria Type 1 </p></div> </a> </div> <div class="information-lines"> <div class="field field--name-field-information-lines field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Publication Date</p> </div> <div class="right"> <p>January 2024</p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Journal</p> </div> <div class="right"> <p><em>Drugs</em></p> </div> </div> </div> <div class="bundle-information-line field__item"> <div class="information-line"> <div class="left"> <p>Authors</p> </div> <div class="right"> <p>Connie Kang</p> </div> </div> </div> </div> </div> <div class="footer"> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </article> </div> </div> </div> <footer class="desktop-footer col-12 d-none d-xl-block" role="contentinfo"> <div class="block-content block-content--type-footer-content block-content--9 block-content--view-mode-full"> <div class="block-content__content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>This site is intended for US healthcare professionals.<br>© 2024 Alnylam Pharmaceuticals, Inc. 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