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Bowes</title> <meta name="description" content="Search results for: Jeremy Bowes"> <meta name="keywords" content="Jeremy Bowes"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Jeremy Bowes"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 56</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Jeremy Bowes</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">56</span> Theoretical Appraisal of Satisfactory Decision: Uncertainty, Evolutionary Ideas and Beliefs, Satisfactory Time Use</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Okay%20Gunes">Okay Gunes</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Unsatisfactory experiences due to an information shortage regarding the future pay-offs of actual choices, yield satisficing decision-making. This research will examine, for the first time in the literature, the motivation behind suboptimal decisions due to uncertainty by subjecting Adam Smith’s and Jeremy Bentham’s assumptions about the nature of the actions that lead to satisficing behavior, in order to clarify the theoretical background of a “consumption-based satisfactory time” concept. The contribution of this paper with respect to the existing literature is threefold: Firstly, it is showed in this paper that Adam Smith’s uncertainty is related to the problem of the constancy of ideas and not related directly to beliefs. Secondly, possessions, as in Jeremy Bentham’s oeuvre, are assumed to be just as pleasing, as protecting and improving the actual or expected quality of life, so long as they reduce any displeasure due to the undesired outcomes of uncertainty. Finally, each consumption decision incurs its own satisfactory time period, owed to not feeling hungry, being healthy, not having transportation…etc. This reveals that the level of satisfaction is indeed a behavioral phenomenon where its value would depend on the simultaneous satisfaction derived from all activities. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=decision-making" title="decision-making">decision-making</a>, <a href="https://publications.waset.org/abstracts/search?q=idea%20and%20belief" title=" idea and belief"> idea and belief</a>, <a href="https://publications.waset.org/abstracts/search?q=satisficing" title=" satisficing"> satisficing</a>, <a href="https://publications.waset.org/abstracts/search?q=uncertainty" title=" uncertainty"> uncertainty</a> </p> <a href="https://publications.waset.org/abstracts/30199/theoretical-appraisal-of-satisfactory-decision-uncertainty-evolutionary-ideas-and-beliefs-satisfactory-time-use" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30199.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">285</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">55</span> Developing a Sustainable Transit Planning Index Using Analytical Hierarchy Process Method for ZEB Implementation in Canada</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mona%20Ghafouri-Azar">Mona Ghafouri-Azar</a>, <a href="https://publications.waset.org/abstracts/search?q=Sara%20Diamond"> Sara Diamond</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Bowes"> Jeremy Bowes</a>, <a href="https://publications.waset.org/abstracts/search?q=Grace%20Yuan"> Grace Yuan</a>, <a href="https://publications.waset.org/abstracts/search?q=Aimee%20Burnett"> Aimee Burnett</a>, <a href="https://publications.waset.org/abstracts/search?q=Michelle%20Wyndham-West"> Michelle Wyndham-West</a>, <a href="https://publications.waset.org/abstracts/search?q=Sara%20Wagner"> Sara Wagner</a>, <a href="https://publications.waset.org/abstracts/search?q=Anand%20Pariyarath"> Anand Pariyarath</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Transportation is the fastest growing source of greenhouse gas emissions worldwide. In Canada, it is responsible for 23% of total CO2emissions from fuel combustion, and emissions from the transportation sector are the second largest source of emissions after the oil and gas sector. Currently, most Canadian public transportation systems rely on buses that operateon fossil fuels.Canada is currently investing billions of dollars to replacediesel buses with electric busesas this isperceived to have a significant impact on climate mitigation. This paper focuses on the possible impacts of zero emission buses (ZEB) on sustainable development, considering three dimensions of sustainability; environmental quality, economic growth, and social development.A sustainable transportation system is one that is safe, affordable, accessible, efficient, and resilient and that contributes minimal emissions of carbon and other pollutants.To enable implementation of these goals, relevant indicators were selected and defined that measure progress towards a sustainable transportation system. These were drawn from Canadian and international examples. Studies compare different European cities in terms of development, sustainability, and infrastructures, by using transport performance indicators. A Normalized Transport Sustainability index measures and compares policies in different urban areas and allows fine-tuning of policies. Analysts use a number ofmethods for sustainable analysis, like cost-benefit analysis (CBA) toassess economic benefit, life-cycle assessment (LCA) to assess social, economic, and environment factors and goals, and multi-criteria decision making (MCDM) analysis which can comparediffering stakeholder preferences.A multi criteria decision making approach is an appropriate methodology to plan and evaluate sustainable transit development and to provide insights and meaningful information for decision makers and transit agencies. It is essential to develop a system thataggregates specific discrete indices to assess the sustainability of transportation systems.Theseprioritize indicators appropriate for the differentCanadian transit system agencies and theirpreferences and requirements. This studywill develop an integrating index that alliesexistingdiscrete indexes to supporta reliable comparison between the current transportation system (diesel buses) and the new ZEB system emerging in Canada. As a first step, theindexes for each category are selected, and the index matrix constructed. Second, the selected indicators arenormalized to remove anyinconsistency between them. Next, the normalized matrix isweighted based on the relative importance of each index to the main domains of sustainability using the analytical hierarchy process (AHP) method. This is accomplished through expert judgement around the relative importance of different attributes with respect to the goals through apairwise comparison matrix. The considerationof multiple environmental, economic, and social factors (including equity and health) is integrated intoa sustainable transit planning index (STPI) which supportsrealistic ZEB implementation in Canada and beyond and is useful to different stakeholders, agencies, and ministries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=zero%20emission%20buses" title="zero emission buses">zero emission buses</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainable%20transit" title=" sustainable transit"> sustainable transit</a>, <a href="https://publications.waset.org/abstracts/search?q=transportation" title=" transportation"> transportation</a>, <a href="https://publications.waset.org/abstracts/search?q=analytical%20hierarchy%20process" title=" analytical hierarchy process"> analytical hierarchy process</a>, <a href="https://publications.waset.org/abstracts/search?q=environment" title=" environment"> environment</a>, <a href="https://publications.waset.org/abstracts/search?q=economy" title=" economy"> economy</a>, <a href="https://publications.waset.org/abstracts/search?q=social" title=" social"> social</a> </p> <a href="https://publications.waset.org/abstracts/147418/developing-a-sustainable-transit-planning-index-using-analytical-hierarchy-process-method-for-zeb-implementation-in-canada" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147418.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">54</span> A Computational Analysis of Flow and Acoustics around a Car Wing Mirror</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aidan%20J.%20Bowes">Aidan J. Bowes</a>, <a href="https://publications.waset.org/abstracts/search?q=Reaz%20Hasan"> Reaz Hasan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The automotive industry is continually aiming to develop the aerodynamics of car body design. This may be for a variety of beneficial reasons such as to increase speed or fuel efficiency by reducing drag. However recently there has been a greater amount of focus on wind noise produced while driving. Designers in this industry seek a combination of both simplicity of approach and overall effectiveness. This combined with the growing availability of commercial CFD (Computational Fluid Dynamics) packages is likely to lead to an increase in the use of RANS (Reynolds Averaged Navier-Stokes) based CFD methods. This is due to these methods often being simpler than other CFD methods, having a lower demand on time and computing power. In this investigation the effectiveness of turbulent flow and acoustic noise prediction using RANS based methods has been assessed for different wing mirror geometries. Three different RANS based models were used, standard k-ε, realizable k-ε and k-ω SST. The merits and limitations of these methods are then discussed, by comparing with both experimental and numerical results found in literature. In general, flow prediction is fairly comparable to more complex LES (Large Eddy Simulation) based methods; in particular for the k-ω SST model. However acoustic noise prediction still leaves opportunities for more improvement using RANS based methods. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acoustics" title="acoustics">acoustics</a>, <a href="https://publications.waset.org/abstracts/search?q=aerodynamics" title=" aerodynamics"> aerodynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=RANS%20models" title=" RANS models"> RANS models</a>, <a href="https://publications.waset.org/abstracts/search?q=turbulent%20flow" title=" turbulent flow"> turbulent flow</a> </p> <a href="https://publications.waset.org/abstracts/17099/a-computational-analysis-of-flow-and-acoustics-around-a-car-wing-mirror" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17099.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">446</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">53</span> Hybrid Knowledge Approach for Determining Health Care Provider Specialty from Patient Diagnoses</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Erin%20Lynne%20Plettenberg">Erin Lynne Plettenberg</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Vickery"> Jeremy Vickery</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In an access-control situation, the role of a user determines whether a data request is appropriate. This paper combines vetted web mining and logic modeling to build a lightweight system for determining the role of a health care provider based only on their prior authorized requests. The model identifies provider roles with 100% recall from very little data. This shows the value of vetted web mining in AI systems, and suggests the impact of the ICD classification on medical practice. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electronic%20medical%20records" title="electronic medical records">electronic medical records</a>, <a href="https://publications.waset.org/abstracts/search?q=information%20extraction" title=" information extraction"> information extraction</a>, <a href="https://publications.waset.org/abstracts/search?q=logic%20modeling" title=" logic modeling"> logic modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=ontology" title=" ontology"> ontology</a>, <a href="https://publications.waset.org/abstracts/search?q=vetted%20web%20mining" title=" vetted web mining"> vetted web mining</a> </p> <a href="https://publications.waset.org/abstracts/81256/hybrid-knowledge-approach-for-determining-health-care-provider-specialty-from-patient-diagnoses" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/81256.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">172</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">52</span> Exploring the Feasibility of Introducing Particular Polyphenols into Cow Milk Naturally through Animal Feeding</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Steve%20H.%20Y.%20Lee">Steve H. Y. Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20P.%20E.%20Spencer"> Jeremy P. E. Spencer</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the present study was to explore the feasibility of enriching polyphenols in cow milk via addition of flavanone-rich citrus pulp to existing animal feed. 8 Holstein lactating cows were enrolled onto the 4 week feeding study. 4 cows were fed the standard farm diet (control group), with another 4 (treatment group) which are fed a standard farm diet mixed with citrus pulp diet. Milk was collected twice a day, 3 times a week. The resulting milk yield and its macronutrient composition as well as lactose content were measured. The milk phenolic compounds were analysed using electrochemical detection (ECD). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=milk" title="milk">milk</a>, <a href="https://publications.waset.org/abstracts/search?q=polyphenol" title=" polyphenol"> polyphenol</a>, <a href="https://publications.waset.org/abstracts/search?q=animal%20feeding" title=" animal feeding"> animal feeding</a>, <a href="https://publications.waset.org/abstracts/search?q=lactating%20cows" title=" lactating cows"> lactating cows</a> </p> <a href="https://publications.waset.org/abstracts/11683/exploring-the-feasibility-of-introducing-particular-polyphenols-into-cow-milk-naturally-through-animal-feeding" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11683.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">298</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">51</span> On the Move: Factors Impacting the Migratory Decision-Making Capabilities of Gambians Relocating to Europe</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Goldsmith">Jeremy Goldsmith</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Gambia, the smallest country in mainland Africa and one of the poorest countries on Earth, is currently experiencing historically unprecedented levels of out-migration to Europe. As a result, Gambians are currently among the top four nationalities emigrating to Europe. The central question that this thesis will address is: what factors impact the migration-related decision-making capabilities of Gambians? Based on interviews with NGOs, as well as those who have migrated and returned, are planning to migrate, and their friends and families, a pattern will emerge. This pattern will be woven into first person narratives which will explore the politico-economic, environmental, and socio-cultural factors that inform individual decision-making with regards to migration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=migration" title="migration">migration</a>, <a href="https://publications.waset.org/abstracts/search?q=The%20Gambia" title=" The Gambia"> The Gambia</a>, <a href="https://publications.waset.org/abstracts/search?q=Africa" title=" Africa"> Africa</a>, <a href="https://publications.waset.org/abstracts/search?q=politico-economic" title=" politico-economic"> politico-economic</a>, <a href="https://publications.waset.org/abstracts/search?q=sociocultural" title=" sociocultural"> sociocultural</a>, <a href="https://publications.waset.org/abstracts/search?q=environmental" title=" environmental"> environmental</a> </p> <a href="https://publications.waset.org/abstracts/60771/on-the-move-factors-impacting-the-migratory-decision-making-capabilities-of-gambians-relocating-to-europe" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60771.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">324</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">50</span> How Tattoos and Brands Impact the Recovery of Sex Trafficking Victim: An Exploratory Study of Sex Trafficking Survivors.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Berry">Jeremy Berry</a>, <a href="https://publications.waset.org/abstracts/search?q=Shannon%20Rodrigue"> Shannon Rodrigue</a>, <a href="https://publications.waset.org/abstracts/search?q=Caroline%20Norris"> Caroline Norris</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study explores the impact of tattoos and/or brands on the recovery of sex trafficking survivors. Many victims of sex trafficking are forced or coerced to take markings of ownership while in the sex trafficking trade in the form of painful tattoos or brands. As a result, victims who are rescued and in recovery often must live with permanent reminders of their traumatic experiences or are left to resort to expensive cosmetic or cover-up jobs, which for many are out of reach. As is often true of domestic violence victims who are left with scars from their abusers, the impact of these permanent markers can delay the healing process and contribute to post-traumatic stress. This study tells the story from the perspectives of the survivors of sex trafficking, how these specific permanent reminders impacted their healing. The study employs a thematic analysis of interviews with sex trafficking victims via focus group interviews. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sex%20trafficking" title="sex trafficking">sex trafficking</a>, <a href="https://publications.waset.org/abstracts/search?q=tattoos" title=" tattoos"> tattoos</a>, <a href="https://publications.waset.org/abstracts/search?q=trauma" title=" trauma"> trauma</a>, <a href="https://publications.waset.org/abstracts/search?q=healing" title=" healing"> healing</a> </p> <a href="https://publications.waset.org/abstracts/135947/how-tattoos-and-brands-impact-the-recovery-of-sex-trafficking-victim-an-exploratory-study-of-sex-trafficking-survivors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/135947.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">191</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">49</span> Open Educational Resources (OER): Deciding upon Openness</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eunice%20H.%20Li">Eunice H. Li</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This e-poster explores some of the issues that are linked to Open Educational Resources (OER). It describes how OER is explained by experts in the field and relates its value in attaining and using knowledge. ‘Open', 'open pedagogy', self-direction, freedom, and autonomy are the main issues identified for the discussion. All of these issues make essential contributions to OER in one way or another. Nevertheless, there are seemingly areas of contentions with regard to applying these concepts in teaching and learning practices. For this e-Poster, it is the teaching-learning aspects of OER that it is primarily concerned with. The basis for the discussion comes from a 2013 critique of OER presented by Jeremy Knox of the University of Edinburgh, tutor of the MSc in Digital Education Programme. This discussion is also supported by the analysis of other research work and papers in this area. The general view on OER is that it is a useful tool for the advancement of learner-centred models of education, but in whatever context, pedagogy cannot be diminished and overlooked. It should take into consideration how to deal with the issues identified above in order to allow learners to gain full benefit from OER. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=open" title="open">open</a>, <a href="https://publications.waset.org/abstracts/search?q=pedagogy" title=" pedagogy"> pedagogy</a>, <a href="https://publications.waset.org/abstracts/search?q=e-learning%20technologies" title=" e-learning technologies"> e-learning technologies</a>, <a href="https://publications.waset.org/abstracts/search?q=autonomy" title=" autonomy"> autonomy</a>, <a href="https://publications.waset.org/abstracts/search?q=knowledge" title=" knowledge"> knowledge</a> </p> <a href="https://publications.waset.org/abstracts/25134/open-educational-resources-oer-deciding-upon-openness" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25134.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">399</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">48</span> Safety System Design and Overfill Protection for Loading Asphalt onto Trucks</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Wendy%20Ampadu">Wendy Ampadu</a>, <a href="https://publications.waset.org/abstracts/search?q=Ray%20Diezmos"> Ray Diezmos</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassan%20Malik"> Hassan Malik</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Hyslob"> Jeremy Hyslob </a> </p> <p class="card-text"><strong>Abstract:</strong></p> There are several technologies out there for use as high-level switches as part of a system for shutting down flow to a vessel. Given that the asphalt truck loading poses issues such as poor visibility, coating, condensation, and fumes, a solution that is robust enough to last in these conditions is often needed in industries. Furthermore, the design of the loading arm, rack, and process equipment should allow for the safety of workers. The objective of this report includes the redesign of structures for use at loading facilities and selecting an overflow technology protection from hot bitumen. The report is based on loading facilities at a Canadian bitumen production company. The engineering design approach was used to create multiple redesign concepts for the loading dock system. Research on overfill systems was also completed by surveying the existing market for technologies and securing quotes from over 20 Canadian and United States instrumentation companies. A final loading dock redesign and level transmitter for overfill protection solution were chosen. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bitumen" title="bitumen">bitumen</a>, <a href="https://publications.waset.org/abstracts/search?q=reliability%20engineering" title=" reliability engineering"> reliability engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=safety%20system" title=" safety system"> safety system</a>, <a href="https://publications.waset.org/abstracts/search?q=process%20safety%20management" title=" process safety management"> process safety management</a>, <a href="https://publications.waset.org/abstracts/search?q=asphalt" title=" asphalt"> asphalt</a>, <a href="https://publications.waset.org/abstracts/search?q=loading%20docks" title=" loading docks"> loading docks</a>, <a href="https://publications.waset.org/abstracts/search?q=tanker%20trucks" title=" tanker trucks"> tanker trucks</a> </p> <a href="https://publications.waset.org/abstracts/128923/safety-system-design-and-overfill-protection-for-loading-asphalt-onto-trucks" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128923.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">47</span> Bio-Mimetic Foot Design for Legged Locomotion over Unstructured Terrain</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hannah%20Kolano">Hannah Kolano</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20Nadan"> Paul Nadan</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Ryan"> Jeremy Ryan</a>, <a href="https://publications.waset.org/abstracts/search?q=Sophia%20Nielsen"> Sophia Nielsen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The hooves of goats and other ruminants, or the family Ruminantia, are uniquely structured to adapt to rough terrain. Their hooves possess a hard outer shell and a soft interior that allow them to both conform to uneven surfaces and hook onto prominent features. In an effort to apply this unique mechanism to a robotics context, artificial feet for a hexapedal robot have been designed based on the hooves of ruminants to improve the robot’s ability to traverse unstructured environments such as those found on a rocky planet or asteroid, as well as in earth-based environments such as rubble, caves, and mountainous regions. The feet were manufactured using a combination of 3D printing and polyurethane casting techniques and attached to a commercially available hexapedal robot. The robot was programmed with a terrain-adaptive gait and proved capable of traversing a variety of uneven surfaces and inclines. This development of more adaptable robotic feet allows legged robots to operate in a wider range of environments and expands their possible applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomimicry" title="biomimicry">biomimicry</a>, <a href="https://publications.waset.org/abstracts/search?q=legged%20locomotion" title=" legged locomotion"> legged locomotion</a>, <a href="https://publications.waset.org/abstracts/search?q=robotic%20foot%20design" title=" robotic foot design"> robotic foot design</a>, <a href="https://publications.waset.org/abstracts/search?q=ruminant%20feet" title=" ruminant feet"> ruminant feet</a>, <a href="https://publications.waset.org/abstracts/search?q=unstructured%20terrain%20navigation" title=" unstructured terrain navigation"> unstructured terrain navigation</a> </p> <a href="https://publications.waset.org/abstracts/123946/bio-mimetic-foot-design-for-legged-locomotion-over-unstructured-terrain" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/123946.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">46</span> Prophet and Philosopher Mohammed: A Precursor of Feminism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Mozammel%20Haque">Mohammad Mozammel Haque</a> </p> <p class="card-text"><strong>Abstract:</strong></p> That feminism is nothing but the name of a belief that women should have the same rights as men needs no telling. The history of modern western feminism is divided into three waves and each is described as dealing with different aspects of the same feminist issues. The first wave refers to the movement of the 19th through early 20th centuries, which dealt mainly with suffrage, working conditions and educational rights for women. The second wave (1960s-1980s) dealt with the inequality of laws and the role of women in society. The third wave (late 1980s-early 2000s) is seen as both a continuation of the second wave and a response to the perceived failures. Mary Wollstonecraft struggled for the emancipation and freedom of the women of Europe, Begum Rokeya brought about revolution for the women of the East and West Bengal, Jeremy Bentham wrote for the independence of women in England. But if feminism refers to the movement of giving women what they deserve, then it won’t be an overstatement to state that Mohammad is the precursor of what we call feminism. This paper investigates the background of official starting of feminism, and also the backdrop of the women of Muhammad’s time. The article, besides showing that this great prophet and philosopher firstly brought about a movement for the education and rights of women and took them out of grave where they were buried alive, also delineates Mohammedan endeavours he attempted to give the women what they ought to have. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=equality" title=" equality"> equality</a>, <a href="https://publications.waset.org/abstracts/search?q=feminism" title=" feminism"> feminism</a>, <a href="https://publications.waset.org/abstracts/search?q=precursor" title=" precursor"> precursor</a> </p> <a href="https://publications.waset.org/abstracts/22734/prophet-and-philosopher-mohammed-a-precursor-of-feminism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22734.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">498</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">45</span> Digital Activism and the Individual: A Utilitarian Perspective</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tania%20Mitra">Tania Mitra</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Digital Activism or Cyber Activism uses digital media as a means to disseminate information and mobilize masses towards a specific goal. When digital activism was first born in the early 1990s, it was primarily used by groups of organized political activists. However, with the advent of social media, online activism has filtered down to the individual- one who does not necessarily belong to or identify with an agenda, group, or political party. A large part of digital activism today stems from the individual’s notion of what is right and wrong. This gives rise to a discourse around descriptive ethics and the implications of the independent digital activist. Although digital activism has paved the way for and bolstered support for causes like the MeToo Movement and Black Lives Matter, the lack of a unified, organized body has led to counterintuitive progressions and suspicions regarding the movements. The paper introduces the ideas of 'clout' culture, click baits, and clicktivism (the phenomenon where activism is reduced to a blind following of the online trends), to discuss the impacts of exclusive digital activism. By using Jeremy Bentham's utilitarian approach to ethics, that places emphasis on the best possible outcome for a society, the paper will show how individual online activism reaching for a larger, more common end can sometimes lead to an undermining of that end, not only in the online space but also how it manifests in the real world. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=digital%20activism" title="digital activism">digital activism</a>, <a href="https://publications.waset.org/abstracts/search?q=ethics" title=" ethics"> ethics</a>, <a href="https://publications.waset.org/abstracts/search?q=independent%20digital%20activist" title=" independent digital activist"> independent digital activist</a>, <a href="https://publications.waset.org/abstracts/search?q=utilitarianism" title=" utilitarianism"> utilitarianism</a> </p> <a href="https://publications.waset.org/abstracts/127981/digital-activism-and-the-individual-a-utilitarian-perspective" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/127981.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">125</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">44</span> Health Promoting Properties of Phytochemicals from Rosemary (Rosmarinus officinalis) for Cancer and Inflammatory Bowel Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20J.%20Johnson">Jeremy J. Johnson</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mediterranean herbs including rosemary (Rosmarinus officinalis) contain a variety of phytochemicals including diterpenes that possess extensive biological activity. Applications of diterpenes, including the more abundant forms carnosol and carnosic acid, have been shown to possess anti-cancer, anti-inflammatory, anti-oxidant, and anti-proliferation properties. To confirm these properties, we have evaluated rosemary extract and selected diterpenes for biological activity in cancer and inflammatory models. Our preliminary data have revealed that select diterpenes can disrupt androgen receptor functionality in prostate and breast cancer cells. This property is unique among natural products for hormone-responsive cancers. The second area of interest has been evaluating rosemary extract and selected diterpenes for activation of sestrin-2, an antioxidant protein, in colon cancer cells. A combination of in vitro and in vivo approaches have been utilized to characterize the activity of rosemary diterpenes in rosemary. Taken together, these results suggest that phytochemicals found in rosemary have distinct pharmacological actions for disrupting cell-signaling pathways in cancer and inflammatory bowel disease. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=rosemary" title="rosemary">rosemary</a>, <a href="https://publications.waset.org/abstracts/search?q=diterpene" title=" diterpene"> diterpene</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer" title=" cancer"> cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammation" title=" inflammation"> inflammation</a> </p> <a href="https://publications.waset.org/abstracts/106363/health-promoting-properties-of-phytochemicals-from-rosemary-rosmarinus-officinalis-for-cancer-and-inflammatory-bowel-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/106363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">146</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">43</span> Deep Learning and Accurate Performance Measure Processes for Cyber Attack Detection among Web Logs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noureddine%20Mohtaram">Noureddine Mohtaram</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Patrix"> Jeremy Patrix</a>, <a href="https://publications.waset.org/abstracts/search?q=Jerome%20Verny"> Jerome Verny</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As an enormous number of online services have been developed into web applications, security problems based on web applications are becoming more serious now. Most intrusion detection systems rely on each request to find the cyber-attack rather than on user behavior, and these systems can only protect web applications against known vulnerabilities rather than certain zero-day attacks. In order to detect new attacks, we analyze the HTTP protocols of web servers to divide them into two categories: normal attacks and malicious attacks. On the other hand, the quality of the results obtained by deep learning (DL) in various areas of big data has given an important motivation to apply it to cybersecurity. Deep learning for attack detection in cybersecurity has the potential to be a robust tool from small transformations to new attacks due to its capability to extract more high-level features. This research aims to take a new approach, deep learning to cybersecurity, to classify these two categories to eliminate attacks and protect web servers of the defense sector which encounters different web traffic compared to other sectors (such as e-commerce, web app, etc.). The result shows that by using a machine learning method, a higher accuracy rate, and a lower false alarm detection rate can be achieved. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anomaly%20detection" title="anomaly detection">anomaly detection</a>, <a href="https://publications.waset.org/abstracts/search?q=HTTP%20protocol" title=" HTTP protocol"> HTTP protocol</a>, <a href="https://publications.waset.org/abstracts/search?q=logs" title=" logs"> logs</a>, <a href="https://publications.waset.org/abstracts/search?q=cyber%20attack" title=" cyber attack"> cyber attack</a>, <a href="https://publications.waset.org/abstracts/search?q=deep%20learning" title=" deep learning"> deep learning</a> </p> <a href="https://publications.waset.org/abstracts/136582/deep-learning-and-accurate-performance-measure-processes-for-cyber-attack-detection-among-web-logs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/136582.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">211</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">42</span> Religious Cognition and Intergroup Bias in the Trolley Dilemma: Experimental Fieldwork in Fiji</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Crystal%20Shackleford">Crystal Shackleford</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Pasek"> Michael Pasek</a>, <a href="https://publications.waset.org/abstracts/search?q=Julia%20%20Smith"> Julia Smith</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Ginges"> Jeremy Ginges</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There is extensive debate about the causal role of religion in intergroup conflict. It is commonly accepted that religious beliefs promote in-group cohesion, but religion is often believed to exacerbate inter-group conflict. Fiji is religiously diverse and has a lengthy history of ethno-religious conflict. In a preregistered field experiment using a modified version of the trolley problem dilemma, Christian and Muslim Fijians were asked, first from their own perspective, and then from their God’s perspective, whether a religious ingroup member should sacrifice their life to save five children who were ingroup or outgroup members. Almost all Muslim participants believed that the person should always sacrifice themselves to save the children. Amongst Christian participants, thinking from God’s perspective increased their likelihood of saying the children should be saved by 35% and removed a 27% gap between responses to saving ingroup versus outgroup children. These results replicate previous findings from a Palestinian sample and demonstrate, in another cross-cultural context with a history of violent conflict, that religious cognition can decrease bias and promote the application of universal moral principles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=conflict" title="conflict">conflict</a>, <a href="https://publications.waset.org/abstracts/search?q=moral%20dilemma" title=" moral dilemma"> moral dilemma</a>, <a href="https://publications.waset.org/abstracts/search?q=psychology" title=" psychology"> psychology</a>, <a href="https://publications.waset.org/abstracts/search?q=religion" title=" religion"> religion</a>, <a href="https://publications.waset.org/abstracts/search?q=thought%20experiments" title=" thought experiments"> thought experiments</a> </p> <a href="https://publications.waset.org/abstracts/108774/religious-cognition-and-intergroup-bias-in-the-trolley-dilemma-experimental-fieldwork-in-fiji" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/108774.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">154</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">41</span> Field Deployment of Corrosion Inhibitor Developed for Sour Oil and Gas Carbon Steel Pipelines</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Moloney">Jeremy Moloney</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A major oil and gas operator in western Canada producing approximately 50,000 BOE per day of sour fluids was experiencing increased water production along with decreased oil production over several years. The higher water volumes being produced meant an increase in the operator’s incumbent corrosion inhibitor (CI) chemical requirements but with reduced oil production revenues. Thus, a cost-effective corrosion inhibitor solution was sought to deliver enhanced corrosion mitigation of the carbon steel pipeline infrastructure but at reduced chemical injection dose rates. This paper presents the laboratory work conducted on the development of a corrosion inhibitor under the operator’s simulated sour operating conditions and then subsequent field testing of the product. The new CI not only provided extremely good levels of general and localized corrosion inhibition and outperformed the incumbent CI under the laboratory test conditions but did so at vastly lower concentrations. In turn, the novel CI product facilitated field chemical injection rates to be optimized and reduced by 40% compared with the incumbent whilst maintaining superior corrosion protection resulting in significant cost savings and associated sustainability benefits for the operator. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbon%20steel" title="carbon steel">carbon steel</a>, <a href="https://publications.waset.org/abstracts/search?q=sour%20gas" title=" sour gas"> sour gas</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogen%20sulphide" title=" hydrogen sulphide"> hydrogen sulphide</a>, <a href="https://publications.waset.org/abstracts/search?q=localized%20corrosion" title=" localized corrosion"> localized corrosion</a>, <a href="https://publications.waset.org/abstracts/search?q=pitting" title=" pitting"> pitting</a>, <a href="https://publications.waset.org/abstracts/search?q=corrosion%20inhibitor" title=" corrosion inhibitor"> corrosion inhibitor</a> </p> <a href="https://publications.waset.org/abstracts/169648/field-deployment-of-corrosion-inhibitor-developed-for-sour-oil-and-gas-carbon-steel-pipelines" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169648.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">85</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">40</span> TomoTherapy® System Repositioning Accuracy According to Treatment Localization</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Veronica%20Sorgato">Veronica Sorgato</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Belhassen"> Jeremy Belhassen</a>, <a href="https://publications.waset.org/abstracts/search?q=Philippe%20Chartier"> Philippe Chartier</a>, <a href="https://publications.waset.org/abstracts/search?q=Roddy%20Sihanath"> Roddy Sihanath</a>, <a href="https://publications.waset.org/abstracts/search?q=Nicolas%20Docquiere"> Nicolas Docquiere</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Yves%20Giraud"> Jean-Yves Giraud</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We analyzed the image-guided radiotherapy method used by the TomoTherapy® System (Accuray Corp.) for patient repositioning in clinical routine. The TomoTherapy® System computes X, Y, Z and roll displacements to match the reference CT, on which the dosimetry has been performed, with the pre-treatment MV CT. The accuracy of the repositioning method has been studied according to the treatment localization. For this, a database of 18774 treatment sessions, performed during 2 consecutive years (2016-2017 period) has been used. The database includes the X, Y, Z and roll displacements proposed by TomoTherapy® System as well as the manual correction of these proposals applied by the radiation therapist. This manual correction aims to further improve the repositioning based on the clinical situation and depends on the structures surrounding the target tumor tissue. The statistical analysis performed on the database aims to define repositioning limits to be used as security and guiding tool for the manual adjustment implemented by the radiation therapist. This tool will participate not only to notify potential repositioning errors but also to further improve patient positioning for optimal treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=accuracy" title="accuracy">accuracy</a>, <a href="https://publications.waset.org/abstracts/search?q=IGRT%20MVCT" title=" IGRT MVCT"> IGRT MVCT</a>, <a href="https://publications.waset.org/abstracts/search?q=image-guided%20radiotherapy%20megavoltage%20computed%20tomography" title=" image-guided radiotherapy megavoltage computed tomography"> image-guided radiotherapy megavoltage computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=statistical%20analysis" title=" statistical analysis"> statistical analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=tomotherapy" title=" tomotherapy"> tomotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=localization" title=" localization"> localization</a> </p> <a href="https://publications.waset.org/abstracts/96757/tomotherapy-system-repositioning-accuracy-according-to-treatment-localization" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96757.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">226</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">39</span> Investigation of the IL23R Psoriasis/PsA Susceptibility Locus</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shraddha%20Rane">Shraddha Rane</a>, <a href="https://publications.waset.org/abstracts/search?q=Richard%20Warren"> Richard Warren</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephen%20Eyre"> Stephen Eyre</a> </p> <p class="card-text"><strong>Abstract:</strong></p> L-23 is a pro-inflammatory molecule that signals T cells to release cytokines such as IL-17A and IL-22. Psoriasis is driven by a dysregulated immune response, within which IL-23 is now thought to play a key role. Genome-wide association studies (GWAS) have identified a number of genetic risk loci that support the involvement of IL-23 signalling in psoriasis; in particular a robust susceptibility locus at a gene encoding a subunit of the IL-23 receptor (IL23R) (Stuart et al., 2015; Tsoi et al., 2012). The lead psoriasis-associated SNP rs9988642 is located approximately 500 bp downstream of IL23R but is in tight linkage disequilibrium (LD) with a missense SNP rs11209026 (R381Q) within IL23R (r2 = 0.85). The minor (G) allele of rs11209026 is present in approximately 7% of the population and is protective for psoriasis and several other autoimmune diseases including IBD, ankylosing spondylitis, RA and asthma. The psoriasis-associated missense SNP R381Q causes an arginine to glutamine substitution in a region of the IL23R protein between the transmembrane domain and the putative JAK2 binding site in the cytoplasmic portion. This substitution is expected to affect the receptor’s surface localisation or signalling ability, rather than IL23R expression. Recent studies have also identified a psoriatic arthritis (PsA)-specific signal at IL23R; thought to be independent from the psoriasis association (Bowes et al., 2015; Budu-Aggrey et al., 2016). The lead PsA-associated SNP rs12044149 is intronic to IL23R and is in LD with likely causal SNPs intersecting promoter and enhancer marks in memory CD8+ T cells (Budu-Aggrey et al., 2016). It is therefore likely that the PsA-specific SNPs affect IL23R function via a different mechanism compared with the psoriasis-specific SNPs. It could be hypothesised that the risk allele for PsA located within the IL23R promoter causes an increase IL23R expression, relative to the protective allele. An increased expression of IL23R might then lead to an exaggerated immune response. The independent genetic signals identified for psoriasis and PsA in this locus indicate that different mechanisms underlie these two conditions; although likely both affecting the function of IL23R. It is very important to further characterise these mechanisms in order to better understand how the IL-23 receptor and its downstream signalling is affected in both diseases. This will help to determine how psoriasis and PsA patients might differentially respond to therapies, particularly IL-23 biologics. To investigate this further we have developed an in vitro model using CD4 T cells which express either wild type IL23R and IL12Rβ1 or mutant IL23R (R381Q) and IL12Rβ1. Model expressing different isotypes of IL23R is also underway to investigate the effects on IL23R expression. We propose to further investigate the variants for Ps and PsA and characterise key intracellular processes related to the variants. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IL23R" title="IL23R">IL23R</a>, <a href="https://publications.waset.org/abstracts/search?q=psoriasis" title=" psoriasis"> psoriasis</a>, <a href="https://publications.waset.org/abstracts/search?q=psoriatic%20arthritis" title=" psoriatic arthritis"> psoriatic arthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=SNP" title=" SNP "> SNP </a> </p> <a href="https://publications.waset.org/abstracts/128643/investigation-of-the-il23r-psoriasispsa-susceptibility-locus" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128643.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">168</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">38</span> Wine Tourism in Rural Russia: Perceptions of Vineyard Managers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Schultz">Jeremy Schultz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this study was to understand the perceptions of vineyard managers in the Krasnodar Region of Southern Russia located between the city of Kransnodar and the Black Sea. In recent years, wine tourism throughout the region has seen tremendous growth due in part to the concurrent growth in the number of tourists vacationing at the Black Sea. This trend has contributed to the development of large-scale wine operations developing in numerous rural locations along the tourists’ travel path. Niche areas of tourism, such as wine tourism, have proven to provide economic viability for rural communities all around the world. Understanding their shared group characteristics while honoring their unique qualities as individuals aids in responsible wine tourism development that provides a sense of well-being for the communities and stakeholders involved. Semi-structured interviews and lived experience methodologies were used in locations that were associated with wine food tourism operations. By understanding management perspectives, it lends insight into sustainable destination management and wine tourism product development, furthering our progress toward ethical, responsible, and financially feasible operations. This research also represents a collaborative effort between Russia and the United States that supports an agenda of sustainable destination development and management. As a global community, we need to continue to investigate stakeholder perceptions and strategic management techniques that best support the pillars upon which responsible tourism was founded. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=wine%20tourism" title="wine tourism">wine tourism</a>, <a href="https://publications.waset.org/abstracts/search?q=tourism%20development" title=" tourism development"> tourism development</a>, <a href="https://publications.waset.org/abstracts/search?q=Russia" title=" Russia"> Russia</a>, <a href="https://publications.waset.org/abstracts/search?q=rural%20tourism" title=" rural tourism"> rural tourism</a> </p> <a href="https://publications.waset.org/abstracts/121456/wine-tourism-in-rural-russia-perceptions-of-vineyard-managers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/121456.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">136</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">37</span> Beliefs about the God of the Other in Intergroup Conflict: Experimental Results from Israel and Palestine</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Crystal%20Shackleford">Crystal Shackleford</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Pasek"> Michael Pasek</a>, <a href="https://publications.waset.org/abstracts/search?q=Allon%20Vishkin"> Allon Vishkin</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Ginges"> Jeremy Ginges</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the Middle East, conflict is often viewed as religiously motivated. In this context, an important question is how we think the religion of the other drives their behavior. If people see conflicts as religious, they may expect the belief of the other to motivate intergroup bias. Beliefs about the motivations of the other impact how we engage with them. Conflict may result if actors believe the other’s religion promotes parochialism. To examine how actors on the ground in Israel-Palestine think about the God of the other as it relates to the other’s behavior towards them, we ran two studies in winter 2019 with an online sample of Jewish Israelis and fieldwork with Palestinians in the West Bank. We asked participants to predict the behavior of an outgroup member participating in an economic game task, dividing the money between themselves and another person, who is either an ingroup or outgroup member. Our experimental manipulation asks participants to predict the behavior of the other when the other is thinking of their God. Both Israelis and Palestinians believed outgroup members would show in-group favoritism, and that group members would give more to their in-group when thinking of their God. We also found that participants thought outgroup members would give more to their own ingroup when thinking of God. In other words, Palestinians predicted that Israelis would give more to fellow Israelis when thinking of God, but also more to Palestinians. Our results suggest that religious belief is seen to promote universal moral reasoning, even in a context with over 70 years of intense conflict. More broadly, this challenges the narrative that religion necessarily motivates intractable conflict. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=conflict" title="conflict">conflict</a>, <a href="https://publications.waset.org/abstracts/search?q=psychology" title=" psychology"> psychology</a>, <a href="https://publications.waset.org/abstracts/search?q=religion" title=" religion"> religion</a>, <a href="https://publications.waset.org/abstracts/search?q=meta-cognition" title=" meta-cognition"> meta-cognition</a>, <a href="https://publications.waset.org/abstracts/search?q=morality" title=" morality"> morality</a> </p> <a href="https://publications.waset.org/abstracts/108806/beliefs-about-the-god-of-the-other-in-intergroup-conflict-experimental-results-from-israel-and-palestine" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/108806.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">138</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">36</span> The Risk of Hyperglycemia Associated with Use of Dolutegravir among Adults Living with HIV in Kampala, Uganda: A Case Control Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Daphine%20Namara">Daphine Namara</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20I.%20Schwartz"> Jeremy I. Schwartz</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20K.%20Tusubira"> Andrew K. Tusubira</a>, <a href="https://publications.waset.org/abstracts/search?q=Willi%20McFarland"> Willi McFarland</a>, <a href="https://publications.waset.org/abstracts/search?q=Caroline%20Birungi"> Caroline Birungi</a>, <a href="https://publications.waset.org/abstracts/search?q=Fred%20C.%20Semitala"> Fred C. Semitala</a>, <a href="https://publications.waset.org/abstracts/search?q=Martin%20Muddu"> Martin Muddu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Emerging evidence suggests a possible association between hyperglycemia and dolutegravir (DTG), a preferred first-line antiretroviral agent in sub-Saharan Africa (SSA). There is a need for rigorous studies to validate this association in the face of increasing DTG use and the burden of non-communicable diseases among people living with HIV (PLHIV). We conducted a case-control study to assess the risk of hyperglycemia associated with the use of DTG among PLHIV attending Mulago ISS Clinic in Kampala. Cases had hyperglycemia, while controls had no hyperglycemia, as confirmed by fasting plasma glucose and oral glucose tolerance tests. Demographic, laboratory, and clinical data were collected using interviewer-administered questionnaires and medical record abstraction. The analysis compared cases and controls on DTG use prior to diagnosis of hyperglycemia while controlling for potential confounders using multivariable logistic regression. We included 204 cases and 231 controls. In multivariable analysis, patients with prior DTG use had seven times greater odds of subsequent diagnosis of hyperglycemia compared to those who had non-DTG-based regimens (adjusted odds ratio [aOR] 7.01, 95% CI 1.96-25.09). The odds of hyperglycemia also increased with age (56 years and above vs. 18-35, aOR 12.38, 95% CI 3.79-40.50) and hypertension (aOR 5.78, 95% CI 2.53-13.21). Our study demonstrates a strong association between prior DTG exposure and subsequent diagnosis of hyperglycemia. Given the benefits of DTG, wide-scale use, and the growing burden of diabetes mellitus (DM) in SSA, there is a need for systematic screening for hyperglycemia and consideration of alternate regimens for those at risk for DM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=HIV" title="HIV">HIV</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperglycemia" title=" hyperglycemia"> hyperglycemia</a>, <a href="https://publications.waset.org/abstracts/search?q=doluteravir" title=" doluteravir"> doluteravir</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes" title=" diabetes"> diabetes</a> </p> <a href="https://publications.waset.org/abstracts/164554/the-risk-of-hyperglycemia-associated-with-use-of-dolutegravir-among-adults-living-with-hiv-in-kampala-uganda-a-case-control-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/164554.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">86</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">35</span> Material Choice Driving Sustainability of 3D Printing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Faludi">Jeremy Faludi</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhongyin%20Hu"> Zhongyin Hu</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahd%20Alrashed"> Shahd Alrashed</a>, <a href="https://publications.waset.org/abstracts/search?q=Christopher%20Braunholz"> Christopher Braunholz</a>, <a href="https://publications.waset.org/abstracts/search?q=Suneesh%20Kaul"> Suneesh Kaul</a>, <a href="https://publications.waset.org/abstracts/search?q=Leulekal%20Kassaye"> Leulekal Kassaye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Environmental impacts of six 3D printers using various materials were compared to determine if material choice drove sustainability, or if other factors such as machine type, machine size, or machine utilization dominate. Cradle-to-grave life-cycle assessments were performed, comparing a commercial-scale FDM machine printing in ABS plastic, a desktop FDM machine printing in ABS, a desktop FDM machine printing in PET and PLA plastics, a polyjet machine printing in its proprietary polymer, an SLA machine printing in its polymer, and an inkjet machine hacked to print in salt and dextrose. All scenarios were scored using ReCiPe Endpoint H methodology to combine multiple impact categories, comparing environmental impacts per part made for several scenarios per machine. Results showed that most printers’ ecological impacts were dominated by electricity use, not materials, and the changes in electricity use due to different plastics was not significant compared to variation from one machine to another. Variation in machine idle time determined impacts per part most strongly. However, material impacts were quite important for the inkjet printer hacked to print in salt: In its optimal scenario, it had up to 1/38th the impacts coreper part as the worst-performing machine in the same scenario. If salt parts were infused with epoxy to make them more physically robust, then much of this advantage disappeared, and material impacts actually dominated or equaled electricity use. Future studies should also measure DMLS and SLS processes / materials. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=3D%20printing" title="3D printing">3D printing</a>, <a href="https://publications.waset.org/abstracts/search?q=additive%20manufacturing" title=" additive manufacturing"> additive manufacturing</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=life-cycle%20assessment" title=" life-cycle assessment"> life-cycle assessment</a>, <a href="https://publications.waset.org/abstracts/search?q=design%20for%20environment" title=" design for environment"> design for environment</a> </p> <a href="https://publications.waset.org/abstracts/16363/material-choice-driving-sustainability-of-3d-printing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">495</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">34</span> Analysis of a Differential System to Get Insights on the Potential Establishment of Microsporidia MB in the Mosquito Population for Malaria Control</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Charlene%20N.%20T.%20Mfangnia">Charlene N. T. Mfangnia</a>, <a href="https://publications.waset.org/abstracts/search?q=Henri%20E.%20Z.%20Tonnang"> Henri E. Z. Tonnang</a>, <a href="https://publications.waset.org/abstracts/search?q=Berge%20Tsanou"> Berge Tsanou</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Herren"> Jeremy Herren</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Microsporidia MB is a recently discovered symbiont capable of blocking the transmission of Plasmodium from mosquitoes to humans. The symbiont can spread both horizontally and vertically among the mosquito population. This dual transmission gives the symbiont the ability to invade the mosquito population. The replacement of the mosquito population by the population of symbiont-infected mosquitoes then appears as a promising strategy for malaria control. In this context, the present study uses differential equations to model the transmission dynamics of Microsporidia MB in the population of female Anopheles mosquitoes. Long-term propagation scenarios of the symbiont, such as extinction, persistence or total infection, are obtained through the determination of the target and basic reproduction numbers, the equilibria, and the study of their stability. The stability is illustrated numerically, and the contribution of vertical and horizontal transmission in the spread of the symbiont is assessed. Data obtained from laboratory experiments are then used to explain the low prevalence observed in nature. The study also shows that the male death rate, the mating rate and the attractiveness of MB-positive mosquitoes are the factors that most influence the transmission of the symbiont. In addition, the introduction of temperature and the study of bifurcations show the significant influence of the environmental condition in the propagation of Microsporidia MB. This finding proves the necessity of taking into account environmental variables for the potential establishment of the symbiont in a new area. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=differential%20equations" title="differential equations">differential equations</a>, <a href="https://publications.waset.org/abstracts/search?q=stability%20analysis" title=" stability analysis"> stability analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=malaria" title=" malaria"> malaria</a>, <a href="https://publications.waset.org/abstracts/search?q=microsporidia%20MB" title=" microsporidia MB"> microsporidia MB</a>, <a href="https://publications.waset.org/abstracts/search?q=horizontal%20transmission" title=" horizontal transmission"> horizontal transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=vertical%20transmission" title=" vertical transmission"> vertical transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=numerical%20illustration" title=" numerical illustration"> numerical illustration</a> </p> <a href="https://publications.waset.org/abstracts/161391/analysis-of-a-differential-system-to-get-insights-on-the-potential-establishment-of-microsporidia-mb-in-the-mosquito-population-for-malaria-control" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161391.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">113</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">33</span> Analysis of the Dynamics of Transmission of Microsporidia MB Inside the Population of Anopheles Mosquitoes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Charlene%20N.%20T.%20Mfangnia">Charlene N. T. Mfangnia</a>, <a href="https://publications.waset.org/abstracts/search?q=Henri%20Tonnang"> Henri Tonnang</a>, <a href="https://publications.waset.org/abstracts/search?q=Berge%20Tsanou"> Berge Tsanou</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Herren"> Jeremy Herren</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Microsporidia MB found in the populations of anopheles is a recently discovered symbiont responsible for the Plasmodium transmission blocking. From early studies, it was established that the symbiont can be transmitted vertically and horizontally. The present study uses compartmental mathematical modelling approach to investigate the dynamics of Microsporidia transmission in the mosquito population with the mindset of establishing a mechanism for use to control malaria. Data and information obtained from laboratory experiments are used to estimate the model parameters with and without temperature dependency of mosquito traits. We carry out the mathematical analysis focusing on the equilibria states and their stability for the autonomous model. Through the modelling experiments, we are able to assess and confirm the contribution of vertical and horizontal transmission in the proliferation of Microsporidia MB in the mosquito population. In addition, the basic and target reproductions are computed, and some long-term behaviours of the model, such as the local (and global) stability of equilibrium points, are rigorously analysed and illustrated numerically. We establish the conditions responsible for the low prevalence of the symbiont-infected mosquitoes observed in nature. Moreover, we identify the male death rate, the mating rate and the attractiveness of MB-positive mosquitoes as mosquito traits that significantly influence the spread of Microsporidia MB. Furthermore, we highlight the influence of temperature in the establishment and persistence of MB-infected mosquitoes in a given area. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=microsporidia%20MB" title="microsporidia MB">microsporidia MB</a>, <a href="https://publications.waset.org/abstracts/search?q=vertical%20transmission" title=" vertical transmission"> vertical transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=horizontal%20transmission" title=" horizontal transmission"> horizontal transmission</a>, <a href="https://publications.waset.org/abstracts/search?q=compartmental%20modelling%20approach" title=" compartmental modelling approach"> compartmental modelling approach</a>, <a href="https://publications.waset.org/abstracts/search?q=temperature-dependent%20mosquito%20traits" title=" temperature-dependent mosquito traits"> temperature-dependent mosquito traits</a>, <a href="https://publications.waset.org/abstracts/search?q=malaria" title=" malaria"> malaria</a>, <a href="https://publications.waset.org/abstracts/search?q=plasmodium-transmission%20blocking" title=" plasmodium-transmission blocking"> plasmodium-transmission blocking</a> </p> <a href="https://publications.waset.org/abstracts/161357/analysis-of-the-dynamics-of-transmission-of-microsporidia-mb-inside-the-population-of-anopheles-mosquitoes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161357.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">130</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">32</span> Deciphering the Action of Neuraminidase in Glioblastoma Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nathalie%20Baeza-Kallee">Nathalie Baeza-Kallee</a>, <a href="https://publications.waset.org/abstracts/search?q=Rapha%C3%ABl%20Berg%C3%A8s"> Raphaël Bergès</a>, <a href="https://publications.waset.org/abstracts/search?q=Victoria%20Hein"> Victoria Hein</a>, <a href="https://publications.waset.org/abstracts/search?q=St%C3%A9phanie%20Cabaret"> Stéphanie Cabaret</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Garcia"> Jeremy Garcia</a>, <a href="https://publications.waset.org/abstracts/search?q=Abiga%C3%ABlle%20Gros"> Abigaëlle Gros</a>, <a href="https://publications.waset.org/abstracts/search?q=Emeline%20Tabouret"> Emeline Tabouret</a>, <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Tchoghandjian"> Aurélie Tchoghandjian</a>, <a href="https://publications.waset.org/abstracts/search?q=Carole%20Colin"> Carole Colin</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominique%20Figarella-Branger"> Dominique Figarella-Branger</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Glioblastoma (GBM) contains cancer stem cells that are resistant to treatment. GBM cancer stem cell expresses glycolipids recognized by the A2B5 antibody. A2B5, induced by the enzyme ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyl transferase 3 (ST8Sia3), plays a crucial role in the proliferation, migration, clonogenicity, and tumorigenesis of GBM cancer stem cells. Our aim was to characterize the resulting effects of neuraminidase that remove A2B5 in order to target GBM cancer stem cells. To this end, we set up a GBM organotypic slice model; quantified A2B5 expression by flow cytometry in U87-MG, U87-ST8Sia3, and GBM cancer stem cell lines, treated or not by neuraminidase; performed RNAseq and DNA methylation profiling; and analyzed the ganglioside expression by liquid chromatography-mass spectrometry in these cell lines, treated or not with neuraminidase. Results demonstrated that neuraminidase decreased A2B5 expression, tumor size, and regrowth after surgical removal in the organotypic slice model but did not induce a distinct transcriptomic or epigenetic signature in GBM CSC lines. RNAseq analysis revealed that OLIG2, CHI3L1, TIMP3, TNFAIP2, and TNFAIP6 transcripts were significantly overexpressed in U87-ST8Sia3 compared to U87-MG. RT-qPCR confirmed these results and demonstrated that neuraminidase decreased gene expression in GBM cancer stem cell lines. Moreover, neuraminidase drastically reduced ganglioside expression in GBM cancer stem cell lines. Neuraminidase, by its pleiotropic action, is an attractive local treatment against GBM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cancer%20stem%20cell" title="cancer stem cell">cancer stem cell</a>, <a href="https://publications.waset.org/abstracts/search?q=ganglioside" title=" ganglioside"> ganglioside</a>, <a href="https://publications.waset.org/abstracts/search?q=glioblastoma" title=" glioblastoma"> glioblastoma</a>, <a href="https://publications.waset.org/abstracts/search?q=targeted%20treatment" title=" targeted treatment"> targeted treatment</a> </p> <a href="https://publications.waset.org/abstracts/171854/deciphering-the-action-of-neuraminidase-in-glioblastoma-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171854.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">31</span> Ethnic Entrepreneurships: Minority Ethnic Students in UiTM Sabah and UMS Perceptions towards Entrepreneurialism Business Interest </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lizinis%20Cassendra%20Frederick%20Dony">Lizinis Cassendra Frederick Dony</a>, <a href="https://publications.waset.org/abstracts/search?q=Dewi%20Binti%20Tajuddin"> Dewi Binti Tajuddin</a>, <a href="https://publications.waset.org/abstracts/search?q=Jirom%20Jeremy%20Frederick%20Dony"> Jirom Jeremy Frederick Dony</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20Nicholas"> Andrew Nicholas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Unemployed graduates have become among the world major concerns lately. 70% of Malaysian graduates are jobless. Due to this concerns, this paper aims to identify major factors influencing Sabah minority ethnic favorable in the entrepreneurialism business interest. Hence, extensive introductory entrepreneurship syllabus clusters development beginning from the early childhood, primary, secondary and university students. This may induce interest appeal and to develop focus group of self-employment. The study focus on 7 indicators consist of demographic profiles variable (DP), social norms (SN), attitude (A), self-efficacy (SE) and business management skills (BMS) with reference to university students’ entrepreneurial intention. This study also partially mediates the relationship between product attractiveness (PA) and the minority ethnic entrepreneurialism business interest (MEEBI), by testifying their direct and indirect relationships. Hence, this study provides new perception towards improving the graduates’ characteristic, capabilities to exploit the business opportunities in the market. Furthermore, this paper will assess the relationship with the product attractiveness(PA) as a mediator. The study encompasses on the type of Sabah minority ethnic (ME) and nature of family own business (FOB) background with the 280 samples students in UiTM Sabah and UMS. The descriptive and random sampling method of research which revealed that majority of the respondents agreed that FOB and entrepreneurship education had positively influenced the ethnic students’ involvement in the entrepreneurial process and career development either full-time or part-time basis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Demographic%20profile%20%28DP%29" title="Demographic profile (DP)">Demographic profile (DP)</a>, <a href="https://publications.waset.org/abstracts/search?q=soci" title=" soci"> soci</a>, <a href="https://publications.waset.org/abstracts/search?q=unemployed%20graduates" title=" unemployed graduates"> unemployed graduates</a>, <a href="https://publications.waset.org/abstracts/search?q=Malaysian%20minority" title=" Malaysian minority"> Malaysian minority</a> </p> <a href="https://publications.waset.org/abstracts/30685/ethnic-entrepreneurships-minority-ethnic-students-in-uitm-sabah-and-ums-perceptions-towards-entrepreneurialism-business-interest" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30685.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">421</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">30</span> Sustainable Adaptation: Social Equity and Local-Level Climate Adaptation Planning in U.S. Cities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Duran%20Fiack">Duran Fiack</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Cumberbatch"> Jeremy Cumberbatch</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Sutherland"> Michael Sutherland</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadine%20Zerphey"> Nadine Zerphey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Civic leaders have increasingly relied upon local climate adaptation plans to identify vulnerabilities, prioritize goals, and implement actions in order to prepare cities for the present and projected effects of global climate change. The concept of sustainability is central to these efforts, as climate adaptation discussions are often framed within the context of economic resilience, environmental protection, and the distribution of climate change impacts across various socioeconomic groups. For urban centers, the climate change issue presents unique challenges for each of these dimensions; however, its potential impacts on marginalized populations are extensive. This study draws from the ‘just sustainabilities’ framework to perform a qualitative analysis of climate adaptation plans prepared by 22 of the 100 largest U.S. cities and examine whether, and to what extent, such initiatives prioritize social equity improvements. Past research has found that the integration of sustainability in urban policy and planning often produces outcomes that favor environmental and economic objectives over social equity improvements. We find that social equity is a particularly prominent theme in local-level climate adaptation efforts, relative to environmental quality and economic development. The findings contribute to the literature on climate adaptation and sustainability within the urban context and offer practical insight for local-level stakeholders concerning potential obstacles and opportunities for the integration of social equity initiatives into climate adaptation planning. Given the likelihood that climate changes will continue to impose unique challenges for marginalized communities in urban areas, advancing our understanding of how social equity concerns are integrated into adaptation efforts is likely to become an increasingly critical area of inquiry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=climate%20adaptation%20plan" title="climate adaptation plan">climate adaptation plan</a>, <a href="https://publications.waset.org/abstracts/search?q=climate%20change" title=" climate change"> climate change</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20equity" title=" social equity"> social equity</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a> </p> <a href="https://publications.waset.org/abstracts/130485/sustainable-adaptation-social-equity-and-local-level-climate-adaptation-planning-in-us-cities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/130485.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">151</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">29</span> Electrochemical Biosensor for the Detection of Botrytis spp. in Temperate Legume Crops</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marzia%20Bilkiss">Marzia Bilkiss</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20J.%20A.%20Shiddiky"> Muhammad J. A. Shiddiky</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20K.%20Masud"> Mostafa K. Masud</a>, <a href="https://publications.waset.org/abstracts/search?q=Prabhakaran%20Sambasivam"> Prabhakaran Sambasivam</a>, <a href="https://publications.waset.org/abstracts/search?q=Ido%20Bar"> Ido Bar</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Brownlie"> Jeremy Brownlie</a>, <a href="https://publications.waset.org/abstracts/search?q=Rebecca%20Ford"> Rebecca Ford</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A greater achievement in the Integrated Disease Management (IDM) to prevent the loss would result from early diagnosis and quantitation of the causal pathogen species for accurate and timely disease control. This could significantly reduce costs to the growers and reduce any flow on impacts to the environment from excessive chemical spraying. Necrotrophic fungal disease botrytis grey mould, caused by Botrytis cinerea and Botrytis fabae, significantly reduce temperate legume yield and grain quality during favourable environmental condition in Australia and worldwide. Several immunogenic and molecular probe-type protocols have been developed for their diagnosis, but these have varying levels of species-specificity, sensitivity, and consequent usefulness within the paddock. To substantially improve speed, accuracy, and sensitivity, advanced nanoparticle-based biosensor approaches have been developed. For this, two sets of primers were designed for both Botrytis cinerea and Botrytis fabae which have shown the species specificity with initial sensitivity of two genomic copies/µl in pure fungal backgrounds using multiplexed quantitative PCR. During further validation, quantitative PCR detected 100 spores on artificially infected legume leaves. Simultaneously an electro-catalytic assay was developed for both target fungal DNA using functionalised magnetic nanoparticles. This was extremely sensitive, able to detect a single spore within a raw total plant nucleic acid extract background. We believe that the translation of this technology to the field will enable quantitative assessment of pathogen load for future accurate decision support of informed botrytis grey mould management. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biosensor" title="biosensor">biosensor</a>, <a href="https://publications.waset.org/abstracts/search?q=botrytis%20grey%20mould" title=" botrytis grey mould"> botrytis grey mould</a>, <a href="https://publications.waset.org/abstracts/search?q=sensitive" title=" sensitive"> sensitive</a>, <a href="https://publications.waset.org/abstracts/search?q=species%20specific" title=" species specific"> species specific</a> </p> <a href="https://publications.waset.org/abstracts/111221/electrochemical-biosensor-for-the-detection-of-botrytis-spp-in-temperate-legume-crops" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/111221.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28</span> Thriving Private-Community Partnerships in Ecotourism: Perspectives from Fiji’s Upper Navua Conservation Area</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Schultz">Jeremy Schultz</a>, <a href="https://publications.waset.org/abstracts/search?q=Kelly%20Bricker"> Kelly Bricker</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ecotourism has proven itself to be a forerunner in the advancement of environmental conservation all the while supporting cultural tradition, uniqueness, and pride among indigenous communities. Successful private-community partnerships associated with ecotourism operations are vital to the overall prosperity of both the businesses and the local communities. Such accomplishments can be seen through numerous livelihood goals including income, food security, health, reduced vulnerability, governance, and empowerment. Private-community partnerships also support global initiatives such as the sustainable development goals and sustainable development frameworks including those proposed by the United Nations World Tourism Organization (WTO). Understanding such partnerships assists not only large organizations such as the WTO, but it also benefits smaller ecotourism operators and entrepreneurs who are trying to achieve their sustainable tourism development goals. This study examined the partnership between an ecotourism company (Rivers Fiji) and two rural villages located in Fiji’s Upper Navua Conservation Area. Focus groups were conducted in each village. Observation journals were also used to record conversations outside of the focus groups. Data were thematically organized and analyzed to offer researcher interpretations and understandings. This research supported the notion that respectful and emboldening partnerships between communities and private enterprise are vital to the composition of successful ecotourism operations that support sustainable development protocol. Understanding these partnerships can assist in shaping future ecotourism development and re-molding existing businesses. This study has offered an example of a thriving partnership through community input and critical researcher analysis. Research has identified six contributing factors to successful ecotourism partnerships, and this study provides additional support to that framework. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=community%20partnerships" title="community partnerships">community partnerships</a>, <a href="https://publications.waset.org/abstracts/search?q=conservation%20areas" title=" conservation areas"> conservation areas</a>, <a href="https://publications.waset.org/abstracts/search?q=ecotourism" title=" ecotourism"> ecotourism</a>, <a href="https://publications.waset.org/abstracts/search?q=Fiji" title=" Fiji"> Fiji</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a> </p> <a href="https://publications.waset.org/abstracts/107902/thriving-private-community-partnerships-in-ecotourism-perspectives-from-fijis-upper-navua-conservation-area" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/107902.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">135</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">27</span> Stroke Rehabilitation via Electroencephalogram Sensors and an Articulated Robot</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Winncy%20Du">Winncy Du</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Nguyen"> Jeremy Nguyen</a>, <a href="https://publications.waset.org/abstracts/search?q=Harpinder%20Dhillon"> Harpinder Dhillon</a>, <a href="https://publications.waset.org/abstracts/search?q=Reinardus%20Justin%20Halim"> Reinardus Justin Halim</a>, <a href="https://publications.waset.org/abstracts/search?q=Clayton%20Haske"> Clayton Haske</a>, <a href="https://publications.waset.org/abstracts/search?q=Trent%20Hughes"> Trent Hughes</a>, <a href="https://publications.waset.org/abstracts/search?q=Marissa%20Ortiz"> Marissa Ortiz</a>, <a href="https://publications.waset.org/abstracts/search?q=Rozy%20Saini"> Rozy Saini</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Stroke often causes death or cerebro-vascular (CV) brain damage. Most patients with CV brain damage lost their motor control on their limbs. This paper focuses on developing a reliable, safe, and non-invasive EEG-based robot-assistant stroke rehabilitation system to help stroke survivors to rapidly restore their motor control functions for their limbs. An electroencephalogram (EEG) recording device (EPOC Headset) and was used to detect a patient’s brain activities. The EEG signals were then processed, classified, and interpreted to the motion intentions, and then converted to a series of robot motion commands. A six-axis articulated robot (AdeptSix 300) was employed to provide the intended motions based on these commends. To ensure the EEG device, the computer, and the robot can communicate to each other, an Arduino microcontroller is used to physically execute the programming codes to a series output pins’ status (HIGH or LOW). Then these “hardware” commends were sent to a 24 V relay to trigger the robot’s motion. A lookup table for various motion intensions and the associated EEG signal patterns were created (through training) and installed in the microcontroller. Thus, the motion intention can be direct determined by comparing the EEG patterns obtaibed from the patient with the look-up table’s EEG patterns; and the corresponding motion commends are sent to the robot to provide the intended motion without going through feature extraction and interpretation each time (a time-consuming process). For safety sake, an extender was designed and attached to the robot’s end effector to ensure the patient is beyond the robot’s workspace. The gripper is also designed to hold the patient’s limb. The test results of this rehabilitation system show that it can accurately interpret the patient’s motion intension and move the patient’s arm to the intended position. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=brain%20waves" title="brain waves">brain waves</a>, <a href="https://publications.waset.org/abstracts/search?q=EEG%20sensor" title=" EEG sensor"> EEG sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=motion%20control" title=" motion control"> motion control</a>, <a href="https://publications.waset.org/abstracts/search?q=robot-assistant%20stroke%20rehabilitation" title=" robot-assistant stroke rehabilitation"> robot-assistant stroke rehabilitation</a> </p> <a href="https://publications.waset.org/abstracts/63586/stroke-rehabilitation-via-electroencephalogram-sensors-and-an-articulated-robot" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/63586.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">383</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Jeremy%20Bowes&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Jeremy%20Bowes&page=2" rel="next">&rsaquo;</a></li> </ul> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a 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