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(PDF) Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids–La(III) complexes | Mustafa Özyürek - Academia.edu
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0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z"></path></svg></button></li></ul></li></ul></div> <script src="//a.academia-assets.com/assets/webpack_bundles/fast_loswp-bundle-97865a4b41eebf6819eddc4c76d29598fe6b0336be57e9b6cde63060c39bfa02.js" defer="defer"></script><script>window.loswp = {}; window.loswp.author = 7771893; window.loswp.bulkDownloadFilterCounts = {}; window.loswp.hasDownloadableAttachment = true; window.loswp.hasViewableAttachments = true; // TODO: just use routes for this window.loswp.loginUrl = "https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F5506156%2FSpectrophotometric_determination_of_ascorbic_acid_by_the_modified_CUPRAC_method_with_extractive_separation_of_flavonoids_La_III_complexes%3Fauto%3Ddownload"; window.loswp.translateUrl = "https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F5506156%2FSpectrophotometric_determination_of_ascorbic_acid_by_the_modified_CUPRAC_method_with_extractive_separation_of_flavonoids_La_III_complexes%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":37385991,"identifier":"Attachment_37385991","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":5506156,"created_at":"2013-12-22T18:33:50.556-08:00","from_world_paper_id":121583968,"updated_at":"2024-11-17T00:34:56.268-08:00","_data":{"grobid_abstract":"The proposed method for ascorbic acid: AA (Vitamin C) determination is based on the oxidation of AA to dehydroascorbic acid with the CUPRAC reagent of total antioxidant capacity assay, i.e., Cu(II)-neocuproine (Nc), in ammonium acetate-containing medium at pH 7, where the absorbance of the formed bis(Nc)-copper(I) chelate is measured at 450 nm. The flavonoids (essentially flavones and flavonols) normally interfering with the CUPRAC procedure were separated with preliminary extraction as their La(III) chelates into ethylacetate (EtAc). The Cu(I)-Nc chelate responsible for color development was formed immediately with AA oxidation. Beer's law was obeyed between 8.0 × 10 −6 and 8.0 × 10 −5 M concentration range, with the equation of the linear calibration curve: A 450 nm = 1.60 × 10 4 C (mol dm −3 ) − 0.0596. The relative standard deviation (R.S.D.) in the analysis of N = 45 synthetic mixtures containing 1.25 × 10 −2 mM AA with flavonoids was 5.3%. The Cu(II)-Nc reagent is a lower redox-potential and therefore more selective oxidant than the Fe(III)-1,10-phenanthroline reagent conventionally used for the same assay. This feature makes the proposed method superior for real samples such as fruit juices containing weak reductants such as citrate, oxalate and tartarate that may otherwise produce positive errors in the Fe(III)-phen method when equilibrium is achieved. The developed method was applied to some commercial fruit juices and pharmaceutical preparations containing Vitamin C + bioflavonoids. The findings of the developed method for fruit juices and pharmaceuticals were statistically alike with those of HPLC. The proposed spectrophotometric method was practical, low-cost, rapid, and could reliably assay AA in the presence of flavonoids without enzymatic procedures open to interferences by enzyme inhibitors.","publication_date":"2007,,","publication_name":"Analytica Chimica Acta","grobid_abstract_attachment_id":"37385991"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids–La(III) complexes","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [7771893]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":37385991,"attachmentType":"pdf"}"><img alt="First page of “Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids–La(III) complexes”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/37385991/mini_magick20190302-15996-j2f9gz.png?1551567440" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids–La(III) complexes</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="7771893" href="https://independent.academia.edu/Mustafa%C3%96zy%C3%BCrek"><img alt="Profile image of Mustafa Özyürek" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/7771893/11041442/12321471/s65_mustafa._zy_rek.jpg" />Mustafa Özyürek</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2007, Analytica Chimica Acta</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">8 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 5506156; 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data-collection-position="2" data-entity-id="92662047" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92662047/Development_of_HPTLC_method_for_the_simultaneous_estimation_of_quercetin_curcumin_and_ascorbic_acid_in_herbal_formulations">Development of HPTLC method for the simultaneous estimation of quercetin, curcumin, and ascorbic acid in herbal formulations</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="40776677" href="https://marwadieducation.academia.edu/NasirVadia">Nasir Vadia</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of the Iranian Chemical Society</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Development of HPTLC method for the 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data-entity-id="16348136" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/16348136/Potentiometric_determination_of_ascorbic_acid_Estimation_of_its_contribution_to_the_total_antioxidant_capacity_of_plant_materials">Potentiometric determination of ascorbic acid: Estimation of its contribution to the total antioxidant capacity of plant materials</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35469858" href="https://kpfu.academia.edu/GuzelZiyatdinova">Guzel Ziyatdinova</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2002</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Potentiometric determination of ascorbic acid: Estimation of its contribution to the total antioxidant capacity of plant materials","attachmentId":42514780,"attachmentType":"pdf","work_url":"https://www.academia.edu/16348136/Potentiometric_determination_of_ascorbic_acid_Estimation_of_its_contribution_to_the_total_antioxidant_capacity_of_plant_materials","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/16348136/Potentiometric_determination_of_ascorbic_acid_Estimation_of_its_contribution_to_the_total_antioxidant_capacity_of_plant_materials"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="49309276" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/49309276/Rapid_qualitative_and_quantitative_HPLC_MS_analysis_of_an_antioxidant_couple_consisted_of_glutathione_and_ascorbic_acid_in_a_pharmaceutical_product">Rapid qualitative and quantitative HPLC/MS analysis of an antioxidant couple consisted of glutathione and ascorbic acid in a pharmaceutical product</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="13838875" href="https://independent.academia.edu/JournalPharmacyPharmacognosyResJPPRes">Journal Pharmacy Pharmacognosy Res JPPRes</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Pharmacy & Pharmacognosy Research, 2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Context: In pharmacy products, glutathione and vitamin C are often present together. Both components not only enhance each other’s action but also protect each other from oxidation, forming an antioxidant couple. The work is devoted to the development of an HPLC method for determining the activity of pharmaceutical preparations containing the antioxidant couple as an active substance. Aims: Develop and validate an HPLC/MS method for the determination of an antioxidant couple of glutathione and ascorbic acid in pharmaceutical products. The method should be fast and simple, that is, analyze both components in one run without derivatization and any preliminary sample preparation. Methods: The Agilent 6125 C SQ LS/DAD/MS instrument was used to detect the two active components simultaneously. MSD was used to detect glutathione; DAD was used to detect ascorbic acid. Results: The run time was 2.0 min. Glutathione was eluted with a retention time of 1.48 min. Its limit of detection was 0.03 μg. Ascorbic acid was eluted with a retention time of 1.02 min. Its limit of detection was 0.01 μg. Recovery of glutathione varied from 92 to 105%, and the recovery of ascorbic acid varied from 99 to 100%. In positive electrospray ionization mode, the spectra of glutathione (Glut.) showed the predominant signals at m/z+ of 308.2, which corresponds to cation (Glut.-H+). Ascorbic acid(AA) is converted into several cations, including AA-H+ and 2AA-Na+, m/z+= 177 and 375. Conclusions: The developed HPLC/MS method for the determination of antioxidant couple consisted of glutathione and ascorbic acid in nasal spray and injection solution was validated for accuracy/recovery, precision, and selectivity. The use of a tandem of a mass spectrometric detector and a diode-array detector is substantiated. The method is fast, simple, sensitive and reproducible, and is suitable for the determination of the antioxidant couple in pharmaceutical products without derivatization or any preliminary sample preparation.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Rapid qualitative and quantitative HPLC/MS analysis of an antioxidant couple consisted of glutathione and ascorbic acid in a pharmaceutical product","attachmentId":67688356,"attachmentType":"pdf","work_url":"https://www.academia.edu/49309276/Rapid_qualitative_and_quantitative_HPLC_MS_analysis_of_an_antioxidant_couple_consisted_of_glutathione_and_ascorbic_acid_in_a_pharmaceutical_product","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/49309276/Rapid_qualitative_and_quantitative_HPLC_MS_analysis_of_an_antioxidant_couple_consisted_of_glutathione_and_ascorbic_acid_in_a_pharmaceutical_product"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="48357345" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/48357345/Electrochemical_and_Spectrophotometric_Methods_for_Polyphenol_and_Ascorbic_Acid_Determination_in_Fruit_and_Vegetable_Extracts">Electrochemical and Spectrophotometric Methods for Polyphenol and Ascorbic Acid Determination in Fruit and Vegetable Extracts</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="61972278" href="https://independent.academia.edu/Mar%C3%ADaLauraLemos">María Laura Lemos</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Food technology and biotechnology</p><p class="ds-related-work--abstract ds2-5-body-sm">Research background. Fresh-cut fruits and vegetables are considered sources of antioxidant compounds. However, their shelf life is limited due to nutritional, quality and safety deterioration. Therefore, in recent decades, various methods have been reported for food processing and preservation, as well as for the determination of antioxidant compounds, due to their many benefits when consumed. The aim of the present work is to compare the performance of electrochemical and spectrophotometric methods in the analysis of the content of polyphenolic compounds and ascorbic acid in extracts from fruits (eggplant), edible roots (carrot) and leaves (rocket, lettuce and chard), and evaluate their capability to detect small changes in the antioxidant content in the eggplant extracts previously irradiated with different UV-C light intensities. Experimental approach. Polyphenolic compounds and ascorbic acid were determined by electrochemical and spectrophotometric methods. An enzymatic biosenso...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Electrochemical and Spectrophotometric Methods for Polyphenol and Ascorbic Acid Determination in Fruit and Vegetable Extracts","attachmentId":67012708,"attachmentType":"pdf","work_url":"https://www.academia.edu/48357345/Electrochemical_and_Spectrophotometric_Methods_for_Polyphenol_and_Ascorbic_Acid_Determination_in_Fruit_and_Vegetable_Extracts","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/48357345/Electrochemical_and_Spectrophotometric_Methods_for_Polyphenol_and_Ascorbic_Acid_Determination_in_Fruit_and_Vegetable_Extracts"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="87602751" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/87602751/A_new_method_for_determination_of_ascorbic_acid_in_fruit_juices_pharmaceuticals_and_biological_samples">A new method for determination of ascorbic acid in fruit juices, pharmaceuticals and biological samples</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="215226724" href="https://independent.academia.edu/EteshJanghel">Etesh Janghel</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A new method for determination of ascorbic acid in fruit juices, pharmaceuticals and biological samples","attachmentId":91766977,"attachmentType":"pdf","work_url":"https://www.academia.edu/87602751/A_new_method_for_determination_of_ascorbic_acid_in_fruit_juices_pharmaceuticals_and_biological_samples","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/87602751/A_new_method_for_determination_of_ascorbic_acid_in_fruit_juices_pharmaceuticals_and_biological_samples"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="117546800" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/117546800/Antioxidant_Activity_of_Flavonoids_of_Different_Polarity_Assayed_by_Modified_ABTS_Cation_Radical_Decolorization_and_EPR_Technique">Antioxidant Activity of Flavonoids of Different Polarity, Assayed by Modified ABTS Cation Radical Decolorization and EPR Technique</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="163392724" href="https://independent.academia.edu/WieslawaBylka">Wieslawa Bylka</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Acta Biologica Cracoviensia Series Botanica, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Antioxidant Activity of Flavonoids of Different Polarity, Assayed by Modified ABTS Cation Radical Decolorization and EPR Technique","attachmentId":114197783,"attachmentType":"pdf","work_url":"https://www.academia.edu/117546800/Antioxidant_Activity_of_Flavonoids_of_Different_Polarity_Assayed_by_Modified_ABTS_Cation_Radical_Decolorization_and_EPR_Technique","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/117546800/Antioxidant_Activity_of_Flavonoids_of_Different_Polarity_Assayed_by_Modified_ABTS_Cation_Radical_Decolorization_and_EPR_Technique"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="4447405" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/4447405/A_selective_catalytic_voltammetric_determination_of_vitamin_C_in_pharmaceutical_preparations_and_complex_matrices_of_fresh_fruit_juices">A selective catalytic voltammetric determination of vitamin C in pharmaceutical preparations and complex matrices of fresh fruit juices</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5476389" href="https://independent.academia.edu/RezaOjani">Reza Ojani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Talanta, 1997</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A selective catalytic voltammetric determination of vitamin C in pharmaceutical preparations and complex matrices of fresh fruit juices","attachmentId":49854177,"attachmentType":"pdf","work_url":"https://www.academia.edu/4447405/A_selective_catalytic_voltammetric_determination_of_vitamin_C_in_pharmaceutical_preparations_and_complex_matrices_of_fresh_fruit_juices","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/4447405/A_selective_catalytic_voltammetric_determination_of_vitamin_C_in_pharmaceutical_preparations_and_complex_matrices_of_fresh_fruit_juices"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="80665827" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/80665827/A_new_UHPLC_MS_MS_method_for_the_determination_of_flavonoids_in_supplements_and_DPPH_UHPLC_UV_method_for_the_evaluation_of_the_radical_scavenging_activity_of_flavonoids">A new UHPLC-MS/MS method for the determination of flavonoids in supplements and DPPH -UHPLC-UV method for the evaluation of the radical scavenging activity of flavonoids</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="178745179" href="https://independent.academia.edu/SylwiaBajkacz">Sylwia Bajkacz</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Food Chemistry, 2018</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A new UHPLC-MS/MS method for the determination of flavonoids in supplements and DPPH -UHPLC-UV method for the evaluation of the radical scavenging activity of flavonoids","attachmentId":86973118,"attachmentType":"pdf","work_url":"https://www.academia.edu/80665827/A_new_UHPLC_MS_MS_method_for_the_determination_of_flavonoids_in_supplements_and_DPPH_UHPLC_UV_method_for_the_evaluation_of_the_radical_scavenging_activity_of_flavonoids","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" 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You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="6083503" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/6083503/The_pro_oxidant_chemistry_of_the_natural_antioxidants_vitamin_C_vitamin_E_carotenoids_and_flavonoids">The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="9166581" href="https://independent.academia.edu/GAlink">Gerrit Alink</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Environmental 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href="https://www.academia.edu/18992958/Flavonoids_as_Analytical_Reagents"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="4" data-entity-id="90123298" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/90123298/Quantitation_of_the_Hydroxycinnamic_Acid_Derivatives_and_the_Glycosides_of_Flavonols_and_Flavones_by_UV_Absorbance_after_Identification_by_LC_MS">Quantitation of the Hydroxycinnamic Acid Derivatives and the Glycosides of Flavonols and Flavones by UV Absorbance after Identification by LC-MS</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="110846" href="https://independent.academia.edu/JamesHarnly">James Harnly</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Agricultural and Food Chemistry, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Quantitation of the Hydroxycinnamic Acid Derivatives and the Glycosides of Flavonols and Flavones by UV Absorbance after Identification by LC-MS","attachmentId":93772638,"attachmentType":"pdf","work_url":"https://www.academia.edu/90123298/Quantitation_of_the_Hydroxycinnamic_Acid_Derivatives_and_the_Glycosides_of_Flavonols_and_Flavones_by_UV_Absorbance_after_Identification_by_LC_MS","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline 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data-author-id="1256050" href="https://utp-my.academia.edu/MuhammadSagir">Muhammad Sagir</a></div><p class="ds-related-work--metadata ds2-5-body-xs">AAPS PharmSci, 2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Evaluation of the antioxidant activity of different flavonoids by the chemiluminescence method","attachmentId":50584333,"attachmentType":"pdf","work_url":"https://www.academia.edu/30123726/Evaluation_of_the_antioxidant_activity_of_different_flavonoids_by_the_chemiluminescence_method","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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class="ds-related-work--metadata ds2-5-body-xs">Talanta, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Flavonoids electrochemical detection in fruit extracts and total antioxidant capacity evaluation","attachmentId":113391503,"attachmentType":"pdf","work_url":"https://www.academia.edu/117568204/Flavonoids_electrochemical_detection_in_fruit_extracts_and_total_antioxidant_capacity_evaluation","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/117568204/Flavonoids_electrochemical_detection_in_fruit_extracts_and_total_antioxidant_capacity_evaluation"><span 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