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<div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><p><br /> <b>Bert L. Vallee</b> (1919-2010) was an Edgar M. Bronfman Distinguished Senior Professor at the <a href="/wiki/Harvard_Medical_School" title="Harvard Medical School">Harvard Medical School</a>. He was the founder and president of the Endowment and the CBBSM (Center for Biochemical & Biophysical Sciences & Medicine). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Early_life_and_career">Early life and career</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bert_L._Vallee&action=edit&section=1" title="Edit section: Early life and career"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vallee received his M.D degree from <a href="/wiki/New_York_University" title="New York University">New York University</a> in 1943 and subsequently held positions at <a href="/wiki/Massachusetts_Institute_of_Technology" title="Massachusetts Institute of Technology">Massachusetts Institute of Technology</a> and Harvard Medical School in Medicine and Biochemistry. Vallee was a member of the Medical and Science Faculty of Harvard University since 1948. He was the Founding Director of the Biophysics Research Laboratory at Harvard (predecessor to the CBBSM), which was established in 1954 by <a href="/wiki/The_Rockefeller_Foundation" class="mw-redirect" title="The Rockefeller Foundation">The Rockefeller Foundation</a>. From 1964 to 1989, Vallee held the Paul C. Cabot Professorship of Biochemistry, and since 1980 he held the Edgar M. Bronfman Distinguished Senior Professorship at Harvard. </p> <div class="mw-heading mw-heading3"><h3 id="Research">Research</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bert_L._Vallee&action=edit&section=2" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>His primary research was in zinc <a href="/wiki/Enzymology" class="mw-redirect" title="Enzymology">enzymology</a>,<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> a field he is credited with establishing and for which he received the Raulin Award. His work on alcohol <a href="/wiki/Dehydrogenase" title="Dehydrogenase">dehydrogenase</a>, a zinc enzyme, led to his interest in the study of the molecular basis of alcohol use and abuse. Dr. Vallee was an expert on emission spectroscopy and the author of more than 600 scientific publications including books. </p><p>He was an Honorary Professor of <a href="/wiki/Tsinghua_University" title="Tsinghua University">Tsinghua University</a>, Beijing, China, the <a href="/wiki/Shanghai_Institute_of_Biochemistry" class="mw-redirect" title="Shanghai Institute of Biochemistry">Shanghai Institute of Biochemistry</a>, the <a href="/wiki/Chinese_Academy_of_Sciences" title="Chinese Academy of Sciences">Chinese Academy of Sciences</a>, <a href="/wiki/Shanghai" title="Shanghai">Shanghai</a>, China, and the <a href="/wiki/Stellenbosch_University" title="Stellenbosch University">Stellenbosch University</a>, Stellenbosch, South Africa. He was a member of the National Academy of Sciences of the US and of the Royal Danish Academy of Science and Letters. He held Honorary Degrees from the <a href="/wiki/Karolinska_Institute" title="Karolinska Institute">Karolinska Institute</a>, Stockholm, the University Degli Studi Di Napoli Federico II, Naples, and the <a href="/wiki/University_of_Munich" class="mw-redirect" title="University of Munich">Ludwig Maximilian University</a>, Munich. </p> <div class="mw-heading mw-heading2"><h2 id="Awards_and_recognitions">Awards and recognitions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bert_L._Vallee&action=edit&section=3" title="Edit section: Awards and recognitions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>He was awarded the Order of Andres Bello, First Class of the Republic of <a href="/wiki/Venezuela" title="Venezuela">Venezuela</a>, and the <a href="/wiki/Gibbs_Medal" class="mw-redirect" title="Gibbs Medal">Gibbs</a>, <a href="/wiki/Kaj_Ulrik_Linderstr%C3%B8m-Lang" title="Kaj Ulrik Linderstrøm-Lang">Linderstrom-Lang</a>, and Rose Medals. </p> <div class="mw-heading mw-heading2"><h2 id="The_Bert_L._&_N._Kuggie_Vallee_Foundation"><span id="The_Bert_L._.26_N._Kuggie_Vallee_Foundation"></span>The Bert L. & N. Kuggie Vallee Foundation</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bert_L._Vallee&action=edit&section=4" title="Edit section: The Bert L. & N. Kuggie Vallee Foundation"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org">The Bert L. and N. Kuggie Vallee Foundation</a> was established in 1996 by Bert L and N. Kuggie Vallee to promote a collegial community of international scientists, to enhance scientific collaboration and communication, and to advance medical education and biomedical research.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>In its initial years, the Foundation's mission to promote dialogue between active and prominent biomedical scientists around the world was achieved by sponsoring visiting professorships at institutions with which Bert Vallee had developed close collaborations and by organizing biennial meetings of this group of biomedical scientists. More recently, the programs have grown and include scientists worldwide. </p><p>The Foundation's programs include: </p> <ul><li>Month-long <a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org/programs/vvp">Vallee Visiting Professorships</a>, which pair senior scientists with premier biomedical research institutes worldwide</li> <li><a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org/programs/yia">Young Investigator Awards</a> providing funding for junior faculty carrying out basic biomedical research</li> <li><a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org/programs/asbmb-award">The Bert and Natalie Vallee Award in Biomedical Science</a> to recognize international achievements in the sciences basic to medicine</li> <li><a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org/programs/lindau">Vallee Fellowships</a> to the <a href="/wiki/Lindau_Nobel_Laureate_Meetings" title="Lindau Nobel Laureate Meetings">Lindau Nobel Laureate Meetings</a> for gifted young post-docs</li> <li><a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org/meetings">Symposia and meetings</a> for Vallee Visiting Professors and Young Investigators to interact in a collegial environment, report on their scientific interests, and address current issues in biomedical science.</li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bert_L._Vallee&action=edit&section=5" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://nobelprize.org/nobel_prizes/medicine/laureates/1992/fischer-autobio.html">"Edmond H. Fischer. The Nobel Prize in Physiology or Medicine 1992"</a>. <a href="/wiki/The_Nobel_Foundation" class="mw-redirect" title="The Nobel Foundation">The Nobel Foundation</a>. <q>In collaboration with Bert Vallee, we were able to demonstrate that these enzymes were in reality calcium-containing metalloproteins.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Edmond+H.+Fischer.+The+Nobel+Prize+in+Physiology+or+Medicine+1992&rft.pub=The+Nobel+Foundation&rft_id=http%3A%2F%2Fnobelprize.org%2Fnobel_prizes%2Fmedicine%2Flaureates%2F1992%2Ffischer-autobio.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ABert+L.+Vallee" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.thevalleefoundation.org/">"Home"</a>. <i>thevalleefoundation.org</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=thevalleefoundation.org&rft.atitle=Home&rft_id=http%3A%2F%2Fwww.thevalleefoundation.org%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ABert+L.+Vallee" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bert_L._Vallee&action=edit&section=6" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://molinterv.aspetjournals.org/content/4/1/10.full">Michael Gottesman: Purely Academic</a> Interview with <a href="/wiki/Michael_M._Gottesman" title="Michael M. Gottesman">Michael Gottesman</a> who studied at Vallee's laboratory.</li> <li><a rel="nofollow" class="external free" href="http://news.harvard.edu/gazette/story/2013/06/bert-lester-vallee/">http://news.harvard.edu/gazette/story/2013/06/bert-lester-vallee/</a> Memorial Minute - Harvard Medical School</li> <li><a rel="nofollow" class="external free" href="http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=8688">http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=8688</a> ASBMB Today, August 2010</li> <li><a rel="nofollow" class="external free" href="http://www.thevalleefoundation.org">http://www.thevalleefoundation.org</a> The Bert L. and N Kuggie Vallee Foundation, Inc.</li> <li><a rel="nofollow" class="external text" href="http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/vallee-bert.pdf">S. James Adelstein and James F. Riordan, "Bert L. Vallee", Biographical Memoirs of the National Academy of Sciences (2014)</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · 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